2EFLA

Crystal structure of the efc domain of formin-binding protein 17
Total Genus 116

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
288
structure length
281
Chain Sequence
MSWGTELWDQFDNLEKHTQWGIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQPKEYKYTSCKAFISNLNEMNDYAGQHEVISENMASQIIVDLARYVQELKQERKSNFHDGRKAQQHIETCWKQLESSKRRFERDCKEADRAQQYFEKMDADINVTKADVEKARQQAQIRHQMAEDSKADYSSILQKFNHEQHEYYHTHIPNIFQKIQEMEERRIVRMGESMKTYAEVDRQVIPIIGKCLDGIVKAAESIDQKNDSQLVIEAYKSGFEPPGDIEFEDYT

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
AH1 (3-7)TI1 (7-10)AH3 (68-156)AH6 (232-257)EMPTYTI3 (161-164)3H2 (226-229)AH5 (208-225)AH4 (166-206)AH2 (11-53)AH7 (261-272)TI2 (64-67)3H1 (157-160)Updating...
connected with : NaN
molecule tags Endocytosis/exocytosis
source organism Homo sapiens
publication title Curved EFC/F-BAR-Domain Dimers Are Joined End to End into a Filament for Membrane Invagination in Endocytosis
pubmed doi rcsb
molecule keywords Formin-binding protein 1
total genus 116
structure length 281
sequence length 288
ec nomenclature
pdb deposition date 2007-02-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2eflA00
5C5BB 3QE6A 2RAJA 1X03A 2Z0OA 2X3XA 4DCNC 4BNEA 1I4LA 3Q0KA 3HAIA 1URUA 2Q12A 3G9GA 3SYVA 3QNIA 2D1LA 4NSWA 3SOGA 2EFLA 3M3WA 4DYLA 3ACOA 3I2WA 2Z0NA 3LLLA 1X04A 4WPEA 3CAZA 3Q84A 3HAJA 3QWEA 3PLTA 4H8SA 2EFKA 4I1QA 4FZSA 2YKTA 2Q13A 1I49A 2ELBA 3DYTA 2RAIA 2FICA 4NQIA 3OK8A 1WDZA 1I4DA 2Z0VA 4WPCA 5C5BA 4ATMA 2D4CA 2X3VA 3ABHA 4AVMA 2RAKA 2V0OA 1I4TA 3HAHA 4AKVA 2C08A 2X3WA 1Y2OA 1ZWWA
chains in the Genus database with same CATH superfamily
4H6IA 4HR1B 4R5JA 3SYVA 1TQUA 1TQTA 3CKDA 2WINM 4DYLA 1U00A 3ACOA 3I2WA 3EJQA 1X04A 4IM0A 2YIVX 3KAWA 2ZXQA 4IM3A 4E3CA 3D4ZA 1GNTA 1TQVA 4FM3A 3QE6A 1E2UA 3D4YA 2QFFA 4IWOA 2D1LA 2QKWA 2F18A 3EJUA 4R5IA 4R5KA 2F7QA 3D50A 4JWEA 2ELBA 3T48A 4AZCA 2KHOA 2GF4A 3HAIA 1QX1A 2OBMA 3BVWA 2YLAA 2EX3B 3BUPA 1DKYA 3PLTA 2EFKA 3A98A 4JWCA 3I04A 4KIKA 3T49A 2GA9D 4WPCA 4EZSA 4HR1A 4AZHA 2RAJA 4IM2A 1HXKA 2N3KA 3BUIA 2ND1A 4UDYX 2JNSA 3DX3A 4H8SA 3DX2A 2WYHA 3D51A 4AVMA 3EJTA 3F7WA 2X3WA 2O0I1 1R5EA 2X3XA 4JNEA 3KDRA 4NSWA 3UITA 2EFLA 3D2EA 4PO2A 4EZYA 3QA8A 3BUQA 4HYBA 4KIKB 4JNFA 1MJGA 2ALWA 2YI8A 3BVVA 1R33A 3BVUA 1GN9A 3CAZA 3Q84A 4JN4A 2YLLA 3O3MB 3EJRA 2MI7A 1QWNA 2OW6A 3HAHA 3B52X 2JNKA 1URUA 2YIBA 2WYIA 3I39X 4JL9A 1ZYLA 4EZPA 4EZRA 4EZXA 3RPMA 2Q13A 1I49A 2GAFD 3ER8C 1HTYA 3T47A 2Q12A 2PY6A 2F7PA 2OW7A 3DPOA 3QWEA 4F01A 3T46A 3ZEDA 2F1BA 2OBLA 4AZ5A 1JQKA 1GNLA 2C08A 1SU7A 4AZBA 4IWQA 4D8JA 1OAOA 5FLEX 3L3PA 3EJPA 3DX4A 2PMRA 2Z0NA 3OWGA 3DX0A 2OZNB 4JWIA 3OK8A 2Z0VA 2YL6A 4EZQA 4WPEA 2D4CA 3FD9A 3DPPA 3CZNA 3D52A 2QXLA 3DDGA 4FZOA 3C7NA 2YIAA 2RAIA 2FICA 2X3VA 4EZOA 1I4TA 3CZSA 3RV1A 2F1AA 2F7OA 3CVRA 2YL9A 4AZ6A 2F7RA 2Z0OA 3BUBA 3DDFA 3ERCC 1O7DC 3M3WA 1DKXA 2NCZA 5TKYA 4E81A 4EZZA 3VEBA 4R5GA 4ATMA 4AZGA 2RAKA 1UPXA 1SU6A 4EZTA 4BNEA 1E1DA 3D2FA 3CV5A 3DX1A 3I01A 2YL5A 3LVTA 3HAJA 4M0MA 1YWMA 5KBPA 1WDZA 3VKHA 4AZIA 2V0OA 4AKVA 4HY9A 4IWPA 1Y2OA 1HWWA 1OA0A 3G9GA 4EZVA 3BVTA 4AZ7A 2FYVA 3QNJA 4JLCA 1LQ7A 3LLLA 4F00A 2RT6A 2X5CA 4EZNA 4G6QA 3RV0A 3VEAA 3DYTA 4NPHA 4NQIA 1DKZA 1TQWA 5C5BB 3T4AG 3Q0KA 3BVXA 1W9MA 4FZPA 3SOGA 4JWDA 3EJSA 1O7DB 4H6HA 4I1QA 1OA1A 4EZUA 1I4DA 4DCNC 2LM0A 1I4LA 3ER9B 2EWFA 3L3OM 1SU8A 2LXYA 1PS3A 2YL8A 3OHXM 5FIGA 3GI7A 1E9VA 2Z8YA 3BLBA 5E84A 3B53X 4FZSA 3LMFA 2YKTA 1QWUA 3KAVA 1TQSA 4R5LA 3ABHA 2YI9A 1ZWWA 1X03A 1R34A 4AZCB 3QNIA 3B51X 4EZWA 4IW0A 4B9QA 3BUDA 2ND0A 3O3NB 2OO2A 4UDXX 5C5BA 3O3OB 3DPQA 1SUFA
chains in the Genus database with same CATH topology
5C5BB 3QE6A 2RAJA 1X03A 2Z0OA 2X3XA 4DCNC 4BNEA 1I4LA 3Q0KA 3HAIA 1URUA 2Q12A 3G9GA 3SYVA 3QNIA 2D1LA 4NSWA 3SOGA 2EFLA 3M3WA 4DYLA 3ACOA 3I2WA 2Z0NA 3LLLA 1X04A 4WPEA 3CAZA 3Q84A 3HAJA 3QWEA 3PLTA 4H8SA 2EFKA 4I1QA 4FZSA 2YKTA 2Q13A 1I49A 2ELBA 3DYTA 2RAIA 2FICA 4NQIA 3OK8A 1WDZA 1I4DA 2Z0VA 4WPCA 5C5BA 4ATMA 2D4CA 2X3VA 3ABHA 4AVMA 2RAKA 2V0OA 1I4TA 3HAHA 4AKVA 2C08A 2X3WA 1Y2OA 1ZWWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5C5B B;  3QE6 A;  2RAJ A;  1X03 A;  2Z0O A;  2X3X A;  4DCN C;  4BNE A;  1I4L A;  3Q0K A;  3HAI A;  1URU A;  2Q12 A;  3G9G A;  3SYV A;  3QNI A;  2D1L A;  4NSW A;  3SOG A;  2EFL A;  3M3W A;  4DYL A;  3ACO A;  3I2W A;  2Z0N A;  3LLL A;  1X04 A;  4WPE A;  3CAZ A;  3Q84 A;  3HAJ A;  3QWE A;  3PLT A;  4H8S A;  2EFK A;  4I1Q A;  4FZS A;  2YKT A;  2Q13 A;  1I49 A;  2ELB A;  3DYT A;  2RAI A;  2FIC A;  4NQI A;  3OK8 A;  1WDZ A;  1I4D A;  2Z0V A;  4WPC A;  5C5B A;  4ATM A;  2D4C A;  2X3V A;  3ABH A;  4AVM A;  2RAK A;  2V0O A;  1I4T A;  3HAH A;  4AKV A;  2C08 A;  2X3W A;  1Y2O A;  1ZWW A; 
#chains in the Genus database with same CATH topology
 4H6I A;  4HR1 B;  4R5J A;  3SYV A;  1TQU A;  1TQT A;  3CKD A;  2WIN M;  4DYL A;  1U00 A;  3ACO A;  3I2W A;  3EJQ A;  1X04 A;  4IM0 A;  2YIV X;  3KAW A;  2ZXQ A;  4IM3 A;  4E3C A;  3D4Z A;  1GNT A;  1TQV A;  4FM3 A;  3QE6 A;  1E2U A;  3D4Y A;  2QFF A;  4IWO A;  2D1L A;  2QKW A;  2F18 A;  3EJU A;  4R5I A;  4R5K A;  2F7Q A;  3D50 A;  4JWE A;  2ELB A;  3T48 A;  4AZC A;  2KHO A;  2GF4 A;  3HAI A;  1QX1 A;  2OBM A;  3BVW A;  2YLA A;  2EX3 B;  3BUP A;  1DKY A;  3PLT A;  2EFK A;  3A98 A;  4JWC A;  3I04 A;  4KIK A;  3T49 A;  2GA9 D;  4WPC A;  4EZS A;  4HR1 A;  4AZH A;  2RAJ A;  4IM2 A;  1HXK A;  2N3K A;  3BUI A;  2ND1 A;  4UDY X;  2JNS A;  3DX3 A;  4H8S A;  3DX2 A;  2WYH A;  3D51 A;  4AVM A;  3EJT A;  3F7W A;  2X3W A;  2O0I 1;  1R5E A;  2X3X A;  4JNE A;  3KDR A;  4NSW A;  3UIT A;  2EFL A;  3D2E A;  4PO2 A;  4EZY A;  3QA8 A;  3BUQ A;  4HYB A;  4KIK B;  4JNF A;  1MJG A;  2ALW A;  2YI8 A;  3BVV A;  1R33 A;  3BVU A;  1GN9 A;  3CAZ A;  3Q84 A;  4JN4 A;  2YLL A;  3O3M B;  3EJR A;  2MI7 A;  1QWN A;  2OW6 A;  3HAH A;  3B52 X;  2JNK A;  1URU A;  2YIB A;  2WYI A;  3I39 X;  4JL9 A;  1ZYL A;  4EZP A;  4EZR A;  4EZX A;  3RPM A;  2Q13 A;  1I49 A;  2GAF D;  3ER8 C;  1HTY A;  3T47 A;  2Q12 A;  2PY6 A;  2F7P A;  2OW7 A;  3DPO A;  3QWE A;  4F01 A;  3T46 A;  3ZED A;  2F1B A;  2OBL A;  4AZ5 A;  1JQK A;  1GNL A;  2C08 A;  1SU7 A;  4AZB A;  4IWQ A;  4D8J A;  1OAO A;  5FLE X;  3L3P A;  3EJP A;  3DX4 A;  2PMR A;  2Z0N A;  3OWG A;  3DX0 A;  2OZN B;  4JWI A;  3OK8 A;  2Z0V A;  2YL6 A;  4EZQ A;  4WPE A;  2D4C A;  3FD9 A;  3DPP A;  3CZN A;  3D52 A;  2QXL A;  3DDG A;  4FZO A;  3C7N A;  2YIA A;  2RAI A;  2FIC A;  2X3V A;  4EZO A;  1I4T A;  3CZS A;  3RV1 A;  2F1A A;  2F7O A;  3CVR A;  2YL9 A;  4AZ6 A;  2F7R A;  2Z0O A;  3BUB A;  3DDF A;  3ERC C;  1O7D C;  3M3W A;  1DKX A;  2NCZ A;  5TKY A;  4E81 A;  4EZZ A;  3VEB A;  4R5G A;  4ATM A;  4AZG A;  2RAK A;  1UPX A;  1SU6 A;  4EZT A;  4BNE A;  1E1D A;  3D2F A;  3CV5 A;  3DX1 A;  3I01 A;  2YL5 A;  3LVT A;  3HAJ A;  4M0M A;  1YWM A;  5KBP A;  1WDZ A;  3VKH A;  4AZI A;  2V0O A;  4AKV A;  4HY9 A;  4IWP A;  1Y2O A;  1HWW A;  1OA0 A;  3G9G A;  4EZV A;  3BVT A;  4AZ7 A;  2FYV A;  3QNJ A;  4JLC A;  1LQ7 A;  3LLL A;  4F00 A;  2RT6 A;  2X5C A;  4EZN A;  4G6Q A;  3RV0 A;  3VEA A;  3DYT A;  4NPH A;  4NQI A;  1DKZ A;  1TQW A;  5C5B B;  3T4A G;  3Q0K A;  3BVX A;  1W9M A;  4FZP A;  3SOG A;  4JWD A;  3EJS A;  1O7D B;  4H6H A;  4I1Q A;  1OA1 A;  4EZU A;  1I4D A;  4DCN C;  2LM0 A;  1I4L A;  3ER9 B;  2EWF A;  3L3O M;  1SU8 A;  2LXY A;  1PS3 A;  2YL8 A;  3OHX M;  5FIG A;  3GI7 A;  1E9V A;  2Z8Y A;  3BLB A;  5E84 A;  3B53 X;  4FZS A;  3LMF A;  2YKT A;  1QWU A;  3KAV A;  1TQS A;  4R5L A;  3ABH A;  2YI9 A;  1ZWW A;  1X03 A;  1R34 A;  4AZC B;  3QNI A;  3B51 X;  4EZW A;  4IW0 A;  4B9Q A;  3BUD A;  2ND0 A;  3O3N B;  2OO2 A;  4UDX X;  5C5B A;  3O3O B;  3DPQ A;  1SUF A; 
#chains in the Genus database with same CATH homology
 5C5B B;  3QE6 A;  2RAJ A;  1X03 A;  2Z0O A;  2X3X A;  4DCN C;  4BNE A;  1I4L A;  3Q0K A;  3HAI A;  1URU A;  2Q12 A;  3G9G A;  3SYV A;  3QNI A;  2D1L A;  4NSW A;  3SOG A;  2EFL A;  3M3W A;  4DYL A;  3ACO A;  3I2W A;  2Z0N A;  3LLL A;  1X04 A;  4WPE A;  3CAZ A;  3Q84 A;  3HAJ A;  3QWE A;  3PLT A;  4H8S A;  2EFK A;  4I1Q A;  4FZS A;  2YKT A;  2Q13 A;  1I49 A;  2ELB A;  3DYT A;  2RAI A;  2FIC A;  4NQI A;  3OK8 A;  1WDZ A;  1I4D A;  2Z0V A;  4WPC A;  5C5B A;  4ATM A;  2D4C A;  2X3V A;  3ABH A;  4AVM A;  2RAK A;  2V0O A;  1I4T A;  3HAH A;  4AKV A;  2C08 A;  2X3W A;  1Y2O A;  1ZWW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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