2EFLA

Crystal structure of the efc domain of formin-binding protein 17
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
288
structure length
281
Chain Sequence
MSWGTELWDQFDNLEKHTQWGIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQPKEYKYTSCKAFISNLNEMNDYAGQHEVISENMASQIIVDLARYVQELKQERKSNFHDGRKAQQHIETCWKQLESSKRRFERDCKEADRAQQYFEKMDADINVTKADVEKARQQAQIRHQMAEDSKADYSSILQKFNHEQHEYYHTHIPNIFQKIQEMEERRIVRMGESMKTYAEVDRQVIPIIGKCLDGIVKAAESIDQKNDSQLVIEAYKSGFEPPGDIEFEDYT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Curved EFC/F-BAR-Domain Dimers Are Joined End to End into a Filament for Membrane Invagination in Endocytosis
pubmed doi rcsb
molecule tags Endocytosis/exocytosis
source organism Homo sapiens
molecule keywords Formin-binding protein 1
total genus 116
structure length 281
sequence length 288
ec nomenclature
pdb deposition date 2007-02-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2eflA00
1I4TA 3ACOA 3HAIA 3HAHA 4WPCA 4AKVA 5C5BA 3Q84A 2X3WA 2RAJA 3I2WA 2EFLA 1I49A 2X3XA 2FICA 1Y2OA 2RAIA 4DYLA 2Q13A 2X3VA 3ABHA 4FZSA 2D1LA 3G9GA 4NSWA 2RAKA 3SOGA 2ELBA 4AVMA 4BNEA 3HAJA 1ZWWA 4H8SA 2V0OA 2Z0OA 1WDZA 2Z0NA 2D4CA 2EFKA 2Q12A 3OK8A 1I4LA 3LLLA 4DCNC 1URUA 3DYTA 1I4DA 3Q0KA 3QNIA 3QE6A 4WPEA 4NQIA 3SYVA 3M3WA 1X03A 1X04A 4ATMA 2C08A 3PLTA 2YKTA 4I1QA 3QWEA 3CAZA 5C5BB 2Z0VA
chains in the Genus database with same CATH superfamily
4EZRA 1OA0A 3Q84A 3I2WA 2FICA 4AZ7A 4HR1B 4JNEA 2D1LA 2MI7A 3HAJA 2V0OA 2Z0NA 3B51X 3DYTA 1JQKA 2ZXQA 4WPEA 3SYVA 2OBLA 3BVUA 3HAIA 1YWMA 5FIGA 2RAJA 1DKYA 2RAIA 1HWWA 4NSWA 2GAFD 4EZNA 2Q12A 3KDRA 2N3KA 3DX3A 3BVTA 1SUFA 2QFFA 4FZOA 4E3CA 1QX1A 2OZNB 1TQUA 2X3XA 1PS3A 4FZSA 1R33A 3BVVA 4F00A 3LVTA 2F7RA 3DX4A 4AZHA 3B52X 1X04A 3PLTA 4UDYX 2QXLA 3HAHA 3D2EA 3QA8A 3EJPA 2EFLA 4E81A 3VEAA 4FM3A 1ZWWA 4H8SA 4M0MA 4EZVA 1ZYLA 3B53X 3L3PA 2WINM 2O0I1 1E9VA 3EJTA 3T49A 4G6QA 4JWEA 4JWDA 3DDFA 2KHOA 2YI9A 4H6IA 4DCNC 1TQTA 1MJGA 3EJUA 1QWUA 4KIKB 3VKHA 3BUPA 1O7DC 3UITA 1SU6A 4BNEA 3BLBA 2ELBA 2EFKA 3Q0KA 1GNLA 2F7PA 2FYVA 3DPOA 1TQVA 4HY9A 3RV0A 4JL9A 4WPCA 3CV5A 1TQWA 3CVRA 4PO2A 4IWPA 2F7QA 4D8JA 4AVMA 3G9GA 2RAKA 3D4ZA 4EZWA 2WYIA 3BUBA 3O3MB 4H6HA 1DKZA 1X03A 3DX1A 3ACOA 2YL5A 4EZPA 2GF4A 2PMRA 3GI7A 4UDXX 2NCZA 3DX0A 4IWQA 2LXYA 1GNTA 1WDZA 4F01A 4AZ5A 2Z8YA 2OO2A 1E2UA 3FD9A 1W9MA 3ER8C 2F7OA 1OAOA 3ERCC 2YLLA 3D4YA 2YL8A 2OW7A 4EZSA 5FLEX 4AZGA 2JNSA 4AZBA 3OK8A 3OWGA 1I4LA 3RPMA 3BVWA 2LM0A 4R5LA 3D51A 3D50A 3DX2A 4AKVA 2GA9D 3L3OM 2X3WA 2YIBA 3O3OB 1Y2OA 3ER9B 2JNKA 2YL9A 2D4CA 1I4DA 3BVXA 3QE6A 4EZUA 4ATMA 4B9QA 2YKTA 2YIAA 3QWEA 2EWFA 2PY6A 5C5BA 3I04A 4EZYA 2YIVX 3BUIA 2WYHA 1E1DA 2ND1A 3SOGA 3C7NA 1TQSA 3M3WA 3LMFA 3CKDA 3CAZA 4AZCB 5KBPA 1U00A 3EJRA 4IM2A 4AZCA 1I49A 3KAWA 4NPHA 1R34A 3T4AG 4JNFA 4R5KA 4HR1A 3BUDA 3KAVA 3VEBA 4JN4A 3T47A 5E84A 4NQIA 4IWOA 1HXKA 4IM0A 4I1QA 2RT6A 4HYBA 4AZIA 4IW0A 3DDGA 5TKYA 1R5EA 4IM3A 4JWCA 2Z0OA 3BUQA 1URUA 3D52A 3EJQA 4R5IA 3CZSA 4EZZA 3QNJA 4EZXA 4EZQA 2YLAA 2ND0A 2Z0VA 4FZPA 2X3VA 3CZNA 3F7WA 3EJSA 1OA1A 1QWNA 3I01A 2X5CA 2C08A 2F1BA 3OHXM 1I4TA 1O7DB 2ALWA 2YI8A 1SU8A 4DYLA 1SU7A 3O3NB 2OW6A 3T46A 3DPQA 3QNIA 3RV1A 4JLCA 1GN9A 1HTYA 1DKXA 3DPPA 1LQ7A 5C5BB 2YL6A 3I39X 1UPXA 2F1AA 2EX3B 2Q13A 4EZOA 3ABHA 3A98A 2QKWA 4AZ6A 3LLLA 3D2FA 2F18A 2OBMA 4JWIA 4R5GA 4R5JA 3T48A 4KIKA 4EZTA 3ZEDA
chains in the Genus database with same CATH topology
1I4TA 3ACOA 3HAIA 3HAHA 4WPCA 4AKVA 5C5BA 3Q84A 2X3WA 2RAJA 3I2WA 2EFLA 1I49A 2X3XA 2FICA 1Y2OA 2RAIA 4DYLA 2Q13A 2X3VA 3ABHA 4FZSA 2D1LA 3G9GA 4NSWA 2RAKA 3SOGA 2ELBA 4AVMA 4BNEA 3HAJA 1ZWWA 4H8SA 2V0OA 2Z0OA 1WDZA 2Z0NA 2D4CA 2EFKA 2Q12A 3OK8A 1I4LA 3LLLA 4DCNC 1URUA 3DYTA 1I4DA 3Q0KA 3QNIA 3QE6A 4WPEA 4NQIA 3SYVA 3M3WA 1X03A 1X04A 4ATMA 2C08A 3PLTA 2YKTA 4I1QA 3QWEA 3CAZA 5C5BB 2Z0VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I4T A;  3ACO A;  3HAI A;  3HAH A;  4WPC A;  4AKV A;  5C5B A;  3Q84 A;  2X3W A;  2RAJ A;  3I2W A;  2EFL A;  1I49 A;  2X3X A;  2FIC A;  1Y2O A;  2RAI A;  4DYL A;  2Q13 A;  2X3V A;  3ABH A;  4FZS A;  2D1L A;  3G9G A;  4NSW A;  2RAK A;  3SOG A;  2ELB A;  4AVM A;  4BNE A;  3HAJ A;  1ZWW A;  4H8S A;  2V0O A;  2Z0O A;  1WDZ A;  2Z0N A;  2D4C A;  2EFK A;  2Q12 A;  3OK8 A;  1I4L A;  3LLL A;  4DCN C;  1URU A;  3DYT A;  1I4D A;  3Q0K A;  3QNI A;  3QE6 A;  4WPE A;  4NQI A;  3SYV A;  3M3W A;  1X03 A;  1X04 A;  4ATM A;  2C08 A;  3PLT A;  2YKT A;  4I1Q A;  3QWE A;  3CAZ A;  5C5B B;  2Z0V A; 
#chains in the Genus database with same CATH topology
 4EZR A;  1OA0 A;  3Q84 A;  3I2W A;  2FIC A;  4AZ7 A;  4HR1 B;  4JNE A;  2D1L A;  2MI7 A;  3HAJ A;  2V0O A;  2Z0N A;  3B51 X;  3DYT A;  1JQK A;  2ZXQ A;  4WPE A;  3SYV A;  2OBL A;  3BVU A;  3HAI A;  1YWM A;  5FIG A;  2RAJ A;  1DKY A;  2RAI A;  1HWW A;  4NSW A;  2GAF D;  4EZN A;  2Q12 A;  3KDR A;  2N3K A;  3DX3 A;  3BVT A;  1SUF A;  2QFF A;  4FZO A;  4E3C A;  1QX1 A;  2OZN B;  1TQU A;  2X3X A;  1PS3 A;  4FZS A;  1R33 A;  3BVV A;  4F00 A;  3LVT A;  2F7R A;  3DX4 A;  4AZH A;  3B52 X;  1X04 A;  3PLT A;  4UDY X;  2QXL A;  3HAH A;  3D2E A;  3QA8 A;  3EJP A;  2EFL A;  4E81 A;  3VEA A;  4FM3 A;  1ZWW A;  4H8S A;  4M0M A;  4EZV A;  1ZYL A;  3B53 X;  3L3P A;  2WIN M;  2O0I 1;  1E9V A;  3EJT A;  3T49 A;  4G6Q A;  4JWE A;  4JWD A;  3DDF A;  2KHO A;  2YI9 A;  4H6I A;  4DCN C;  1TQT A;  1MJG A;  3EJU A;  1QWU A;  4KIK B;  3VKH A;  3BUP A;  1O7D C;  3UIT A;  1SU6 A;  4BNE A;  3BLB A;  2ELB A;  2EFK A;  3Q0K A;  1GNL A;  2F7P A;  2FYV A;  3DPO A;  1TQV A;  4HY9 A;  3RV0 A;  4JL9 A;  4WPC A;  3CV5 A;  1TQW A;  3CVR A;  4PO2 A;  4IWP A;  2F7Q A;  4D8J A;  4AVM A;  3G9G A;  2RAK A;  3D4Z A;  4EZW A;  2WYI A;  3BUB A;  3O3M B;  4H6H A;  1DKZ A;  1X03 A;  3DX1 A;  3ACO A;  2YL5 A;  4EZP A;  2GF4 A;  2PMR A;  3GI7 A;  4UDX X;  2NCZ A;  3DX0 A;  4IWQ A;  2LXY A;  1GNT A;  1WDZ A;  4F01 A;  4AZ5 A;  2Z8Y A;  2OO2 A;  1E2U A;  3FD9 A;  1W9M A;  3ER8 C;  2F7O A;  1OAO A;  3ERC C;  2YLL A;  3D4Y A;  2YL8 A;  2OW7 A;  4EZS A;  5FLE X;  4AZG A;  2JNS A;  4AZB A;  3OK8 A;  3OWG A;  1I4L A;  3RPM A;  3BVW A;  2LM0 A;  4R5L A;  3D51 A;  3D50 A;  3DX2 A;  4AKV A;  2GA9 D;  3L3O M;  2X3W A;  2YIB A;  3O3O B;  1Y2O A;  3ER9 B;  2JNK A;  2YL9 A;  2D4C A;  1I4D A;  3BVX A;  3QE6 A;  4EZU A;  4ATM A;  4B9Q A;  2YKT A;  2YIA A;  3QWE A;  2EWF A;  2PY6 A;  5C5B A;  3I04 A;  4EZY A;  2YIV X;  3BUI A;  2WYH A;  1E1D A;  2ND1 A;  3SOG A;  3C7N A;  1TQS A;  3M3W A;  3LMF A;  3CKD A;  3CAZ A;  4AZC B;  5KBP A;  1U00 A;  3EJR A;  4IM2 A;  4AZC A;  1I49 A;  3KAW A;  4NPH A;  1R34 A;  3T4A G;  4JNF A;  4R5K A;  4HR1 A;  3BUD A;  3KAV A;  3VEB A;  4JN4 A;  3T47 A;  5E84 A;  4NQI A;  4IWO A;  1HXK A;  4IM0 A;  4I1Q A;  2RT6 A;  4HYB A;  4AZI A;  4IW0 A;  3DDG A;  5TKY A;  1R5E A;  4IM3 A;  4JWC A;  2Z0O A;  3BUQ A;  1URU A;  3D52 A;  3EJQ A;  4R5I A;  3CZS A;  4EZZ A;  3QNJ A;  4EZX A;  4EZQ A;  2YLA A;  2ND0 A;  2Z0V A;  4FZP A;  2X3V A;  3CZN A;  3F7W A;  3EJS A;  1OA1 A;  1QWN A;  3I01 A;  2X5C A;  2C08 A;  2F1B A;  3OHX M;  1I4T A;  1O7D B;  2ALW A;  2YI8 A;  1SU8 A;  4DYL A;  1SU7 A;  3O3N B;  2OW6 A;  3T46 A;  3DPQ A;  3QNI A;  3RV1 A;  4JLC A;  1GN9 A;  1HTY A;  1DKX A;  3DPP A;  1LQ7 A;  5C5B B;  2YL6 A;  3I39 X;  1UPX A;  2F1A A;  2EX3 B;  2Q13 A;  4EZO A;  3ABH A;  3A98 A;  2QKW A;  4AZ6 A;  3LLL A;  3D2F A;  2F18 A;  2OBM A;  4JWI A;  4R5G A;  4R5J A;  3T48 A;  4KIK A;  4EZT A;  3ZED A; 
#chains in the Genus database with same CATH homology
 1I4T A;  3ACO A;  3HAI A;  3HAH A;  4WPC A;  4AKV A;  5C5B A;  3Q84 A;  2X3W A;  2RAJ A;  3I2W A;  2EFL A;  1I49 A;  2X3X A;  2FIC A;  1Y2O A;  2RAI A;  4DYL A;  2Q13 A;  2X3V A;  3ABH A;  4FZS A;  2D1L A;  3G9G A;  4NSW A;  2RAK A;  3SOG A;  2ELB A;  4AVM A;  4BNE A;  3HAJ A;  1ZWW A;  4H8S A;  2V0O A;  2Z0O A;  1WDZ A;  2Z0N A;  2D4C A;  2EFK A;  2Q12 A;  3OK8 A;  1I4L A;  3LLL A;  4DCN C;  1URU A;  3DYT A;  1I4D A;  3Q0K A;  3QNI A;  3QE6 A;  4WPE A;  4NQI A;  3SYV A;  3M3W A;  1X03 A;  1X04 A;  4ATM A;  2C08 A;  3PLT A;  2YKT A;  4I1Q A;  3QWE A;  3CAZ A;  5C5B B;  2Z0V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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