2EFLA

Crystal structure of the efc domain of formin-binding protein 17
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
288
structure length
281
Chain Sequence
MSWGTELWDQFDNLEKHTQWGIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQPKEYKYTSCKAFISNLNEMNDYAGQHEVISENMASQIIVDLARYVQELKQERKSNFHDGRKAQQHIETCWKQLESSKRRFERDCKEADRAQQYFEKMDADINVTKADVEKARQQAQIRHQMAEDSKADYSSILQKFNHEQHEYYHTHIPNIFQKIQEMEERRIVRMGESMKTYAEVDRQVIPIIGKCLDGIVKAAESIDQKNDSQLVIEAYKSGFEPPGDIEFEDYT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Endocytosis/exocytosis
molecule keywords Formin-binding protein 1
publication title Curved EFC/F-BAR-Domain Dimers Are Joined End to End into a Filament for Membrane Invagination in Endocytosis
pubmed doi rcsb
source organism Homo sapiens
total genus 116
structure length 281
sequence length 288
ec nomenclature
pdb deposition date 2007-02-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2eflA00
4FZSA 2Q12A 3ABHA 1I4LA 4WPEA 3M3WA 2RAKA 3G9GA 2RAJA 3HAJA 2D1LA 3ACOA 4I1QA 4AVMA 3I2WA 2D4CA 3Q84A 2X3WA 2ELBA 2X3XA 1I49A 2YKTA 2Z0OA 3QE6A 4AKVA 4DYLA 1X04A 2FICA 1WDZA 4ATMA 2Z0NA 3QWEA 1URUA 2X3VA 4NQIA 1ZWWA 4NSWA 2RAIA 2EFLA 1I4DA 3Q0KA 3HAIA 3PLTA 4BNEA 3SYVA 1I4TA 1Y2OA 2C08A 3DYTA 2V0OA 3QNIA 2Q13A 5C5BA 2EFKA 2Z0VA 5C5BB 3CAZA 3SOGA 1X03A 3LLLA 4H8SA 4WPCA 3HAHA 3OK8A 4DCNC
chains in the Genus database with same CATH superfamily
4JWIA 4AZ5A 3O3OB 2X3XA 3O3NB 4NQIA 2X3VA 3D52A 3DX4A 4JLCA 1R33A 2EWFA 3KAWA 1GNTA 3DDFA 2Z0VA 3F7WA 4EZUA 2PMRA 3B53X 2N3KA 3LLLA 2F7OA 4IWOA 2YL6A 4WPEA 2YKTA 3DX1A 5C5BB 3HAHA 3OK8A 3T46A 2LXYA 1QWUA 1E9VA 2WINM 2YL8A 1O7DC 1X04A 3RV1A 4EZZA 3QWEA 1URUA 2WYHA 3DPOA 1Y2OA 2V0OA 2RT6A 3DDGA 3A98A 4M0MA 3ER8C 4AVMA 4EZRA 3BVWA 2FICA 1GNLA 2YI8A 3DYTA 2OZNB 2KHOA 3BVVA 1U00A 4AZ7A 4R5GA 4HR1A 3UITA 4H8SA 3D4YA 2LM0A 4JWDA 1QX1A 3GI7A 3EJUA 2RAKA 2NCZA 2YIAA 3Q84A 2O0I1 3CZSA 3DPPA 2Z0NA 2F18A 3L3OM 3VEBA 3EJSA 4H6IA 4H6HA 1DKZA 4UDXX 3BVUA 2Q12A 3D4ZA 3ACOA 2F1AA 1SU8A 4E81A 2GF4A 1W9MA 3SYVA 4F00A 2YLAA 4EZSA 1TQTA 2ND1A 3EJPA 4JWCA 1TQVA 3BUBA 3OWGA 2F7QA 2X3WA 2F7RA 4AKVA 2JNSA 4KIKA 4JL9A 1ZWWA 3B52X 4EZWA 3BUPA 4EZQA 3EJQA 3KAVA 3T4AG 3L3PA 3D50A 2X5CA 2F1BA 4AZHA 1ZYLA 2YIBA 4F01A 4EZVA 3CV5A 3HAJA 4AZ6A 1WDZA 2EX3B 4JWEA 4IWPA 4JNFA 1I4TA 2C08A 1YWMA 1GN9A 3EJTA 1I4LA 1E2UA 3O3MB 2RAJA 4R5JA 2ZXQA 3I39X 3LVTA 4IWQA 3CVRA 2GAFD 4ATMA 4NPHA 4B9QA 2JNKA 3T48A 4HR1B 1HWWA 5FIGA 3VEAA 4AZCA 3CZNA 1JQKA 1TQUA 3D2FA 2ALWA 3D2EA 2GA9D 4I1QA 3BVXA 1I49A 1SU7A 4E3CA 3RV0A 2F7PA 1HTYA 4FM3A 3VKHA 1I4DA 4EZXA 2OW6A 5E84A 2OBLA 4HY9A 1DKXA 4DCNC 3T49A 1R5EA 2YI9A 3DX3A 3ZEDA 1R34A 3ERCC 3KDRA 4IM3A 3BVTA 3BUIA 3LMFA 4IW0A 1E1DA 2YL5A 2Z8YA 2OO2A 3BUQA 4KIKB 4R5IA 2QKWA 1HXKA 5FLEX 4FZOA 2QXLA 2OW7A 4EZNA 3CKDA 1SU6A 3DX2A 3ABHA 3B51X 5KBPA 3G9GA 4R5KA 1PS3A 4DYLA 3ER9B 2ND0A 4HYBA 3BLBA 3Q0KA 3PLTA 3QA8A 4AZBA 1TQSA 5C5BA 4EZYA 3I01A 4FZSA 3QNJA 4AZIA 2MI7A 3I2WA 2D4CA 3C7NA 2PY6A 3DPQA 2WYIA 4UDYX 1MJGA 1LQ7A 3I04A 4NSWA 2RAIA 4AZCB 4JN4A 2EFKA 1QWNA 1OA1A 5TKYA 3CAZA 3SOGA 3DX0A 3EJRA 1UPXA 2FYVA 3BUDA 2YLLA 3T47A 1OA0A 4IM2A 2ELBA 4D8JA 4G6QA 4IM0A 2EFLA 4BNEA 3QNIA 2YL9A 1DKYA 1OAOA 4WPCA 4AZGA 1O7DB 2YIVX 3D51A 2QFFA 3M3WA 4EZPA 2D1LA 3OHXM 2Z0OA 3QE6A 3FD9A 4JNEA 3RPMA 2OBMA 4R5LA 1TQWA 4FZPA 3HAIA 2Q13A 4EZOA 4EZTA 4PO2A 1X03A 1SUFA
chains in the Genus database with same CATH topology
4FZSA 2Q12A 3ABHA 1I4LA 4WPEA 3M3WA 2RAKA 3G9GA 2RAJA 3HAJA 2D1LA 3ACOA 4I1QA 4AVMA 3I2WA 2D4CA 3Q84A 2X3WA 2ELBA 2X3XA 1I49A 2YKTA 2Z0OA 3QE6A 4AKVA 4DYLA 1X04A 2FICA 1WDZA 4ATMA 2Z0NA 3QWEA 1URUA 2X3VA 4NQIA 1ZWWA 4NSWA 2RAIA 2EFLA 1I4DA 3Q0KA 3HAIA 3PLTA 4BNEA 3SYVA 1I4TA 1Y2OA 2C08A 3DYTA 2V0OA 3QNIA 2Q13A 5C5BA 2EFKA 2Z0VA 5C5BB 3CAZA 3SOGA 1X03A 3LLLA 4H8SA 4WPCA 3HAHA 3OK8A 4DCNC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FZS A;  2Q12 A;  3ABH A;  1I4L A;  4WPE A;  3M3W A;  2RAK A;  3G9G A;  2RAJ A;  3HAJ A;  2D1L A;  3ACO A;  4I1Q A;  4AVM A;  3I2W A;  2D4C A;  3Q84 A;  2X3W A;  2ELB A;  2X3X A;  1I49 A;  2YKT A;  2Z0O A;  3QE6 A;  4AKV A;  4DYL A;  1X04 A;  2FIC A;  1WDZ A;  4ATM A;  2Z0N A;  3QWE A;  1URU A;  2X3V A;  4NQI A;  1ZWW A;  4NSW A;  2RAI A;  2EFL A;  1I4D A;  3Q0K A;  3HAI A;  3PLT A;  4BNE A;  3SYV A;  1I4T A;  1Y2O A;  2C08 A;  3DYT A;  2V0O A;  3QNI A;  2Q13 A;  5C5B A;  2EFK A;  2Z0V A;  5C5B B;  3CAZ A;  3SOG A;  1X03 A;  3LLL A;  4H8S A;  4WPC A;  3HAH A;  3OK8 A;  4DCN C; 
#chains in the Genus database with same CATH topology
 4JWI A;  4AZ5 A;  3O3O B;  2X3X A;  3O3N B;  4NQI A;  2X3V A;  3D52 A;  3DX4 A;  4JLC A;  1R33 A;  2EWF A;  3KAW A;  1GNT A;  3DDF A;  2Z0V A;  3F7W A;  4EZU A;  2PMR A;  3B53 X;  2N3K A;  3LLL A;  2F7O A;  4IWO A;  2YL6 A;  4WPE A;  2YKT A;  3DX1 A;  5C5B B;  3HAH A;  3OK8 A;  3T46 A;  2LXY A;  1QWU A;  1E9V A;  2WIN M;  2YL8 A;  1O7D C;  1X04 A;  3RV1 A;  4EZZ A;  3QWE A;  1URU A;  2WYH A;  3DPO A;  1Y2O A;  2V0O A;  2RT6 A;  3DDG A;  3A98 A;  4M0M A;  3ER8 C;  4AVM A;  4EZR A;  3BVW A;  2FIC A;  1GNL A;  2YI8 A;  3DYT A;  2OZN B;  2KHO A;  3BVV A;  1U00 A;  4AZ7 A;  4R5G A;  4HR1 A;  3UIT A;  4H8S A;  3D4Y A;  2LM0 A;  4JWD A;  1QX1 A;  3GI7 A;  3EJU A;  2RAK A;  2NCZ A;  2YIA A;  3Q84 A;  2O0I 1;  3CZS A;  3DPP A;  2Z0N A;  2F18 A;  3L3O M;  3VEB A;  3EJS A;  4H6I A;  4H6H A;  1DKZ A;  4UDX X;  3BVU A;  2Q12 A;  3D4Z A;  3ACO A;  2F1A A;  1SU8 A;  4E81 A;  2GF4 A;  1W9M A;  3SYV A;  4F00 A;  2YLA A;  4EZS A;  1TQT A;  2ND1 A;  3EJP A;  4JWC A;  1TQV A;  3BUB A;  3OWG A;  2F7Q A;  2X3W A;  2F7R A;  4AKV A;  2JNS A;  4KIK A;  4JL9 A;  1ZWW A;  3B52 X;  4EZW A;  3BUP A;  4EZQ A;  3EJQ A;  3KAV A;  3T4A G;  3L3P A;  3D50 A;  2X5C A;  2F1B A;  4AZH A;  1ZYL A;  2YIB A;  4F01 A;  4EZV A;  3CV5 A;  3HAJ A;  4AZ6 A;  1WDZ A;  2EX3 B;  4JWE A;  4IWP A;  4JNF A;  1I4T A;  2C08 A;  1YWM A;  1GN9 A;  3EJT A;  1I4L A;  1E2U A;  3O3M B;  2RAJ A;  4R5J A;  2ZXQ A;  3I39 X;  3LVT A;  4IWQ A;  3CVR A;  2GAF D;  4ATM A;  4NPH A;  4B9Q A;  2JNK A;  3T48 A;  4HR1 B;  1HWW A;  5FIG A;  3VEA A;  4AZC A;  3CZN A;  1JQK A;  1TQU A;  3D2F A;  2ALW A;  3D2E A;  2GA9 D;  4I1Q A;  3BVX A;  1I49 A;  1SU7 A;  4E3C A;  3RV0 A;  2F7P A;  1HTY A;  4FM3 A;  3VKH A;  1I4D A;  4EZX A;  2OW6 A;  5E84 A;  2OBL A;  4HY9 A;  1DKX A;  4DCN C;  3T49 A;  1R5E A;  2YI9 A;  3DX3 A;  3ZED A;  1R34 A;  3ERC C;  3KDR A;  4IM3 A;  3BVT A;  3BUI A;  3LMF A;  4IW0 A;  1E1D A;  2YL5 A;  2Z8Y A;  2OO2 A;  3BUQ A;  4KIK B;  4R5I A;  2QKW A;  1HXK A;  5FLE X;  4FZO A;  2QXL A;  2OW7 A;  4EZN A;  3CKD A;  1SU6 A;  3DX2 A;  3ABH A;  3B51 X;  5KBP A;  3G9G A;  4R5K A;  1PS3 A;  4DYL A;  3ER9 B;  2ND0 A;  4HYB A;  3BLB A;  3Q0K A;  3PLT A;  3QA8 A;  4AZB A;  1TQS A;  5C5B A;  4EZY A;  3I01 A;  4FZS A;  3QNJ A;  4AZI A;  2MI7 A;  3I2W A;  2D4C A;  3C7N A;  2PY6 A;  3DPQ A;  2WYI A;  4UDY X;  1MJG A;  1LQ7 A;  3I04 A;  4NSW A;  2RAI A;  4AZC B;  4JN4 A;  2EFK A;  1QWN A;  1OA1 A;  5TKY A;  3CAZ A;  3SOG A;  3DX0 A;  3EJR A;  1UPX A;  2FYV A;  3BUD A;  2YLL A;  3T47 A;  1OA0 A;  4IM2 A;  2ELB A;  4D8J A;  4G6Q A;  4IM0 A;  2EFL A;  4BNE A;  3QNI A;  2YL9 A;  1DKY A;  1OAO A;  4WPC A;  4AZG A;  1O7D B;  2YIV X;  3D51 A;  2QFF A;  3M3W A;  4EZP A;  2D1L A;  3OHX M;  2Z0O A;  3QE6 A;  3FD9 A;  4JNE A;  3RPM A;  2OBM A;  4R5L A;  1TQW A;  4FZP A;  3HAI A;  2Q13 A;  4EZO A;  4EZT A;  4PO2 A;  1X03 A;  1SUF A; 
#chains in the Genus database with same CATH homology
 4FZS A;  2Q12 A;  3ABH A;  1I4L A;  4WPE A;  3M3W A;  2RAK A;  3G9G A;  2RAJ A;  3HAJ A;  2D1L A;  3ACO A;  4I1Q A;  4AVM A;  3I2W A;  2D4C A;  3Q84 A;  2X3W A;  2ELB A;  2X3X A;  1I49 A;  2YKT A;  2Z0O A;  3QE6 A;  4AKV A;  4DYL A;  1X04 A;  2FIC A;  1WDZ A;  4ATM A;  2Z0N A;  3QWE A;  1URU A;  2X3V A;  4NQI A;  1ZWW A;  4NSW A;  2RAI A;  2EFL A;  1I4D A;  3Q0K A;  3HAI A;  3PLT A;  4BNE A;  3SYV A;  1I4T A;  1Y2O A;  2C08 A;  3DYT A;  2V0O A;  3QNI A;  2Q13 A;  5C5B A;  2EFK A;  2Z0V A;  5C5B B;  3CAZ A;  3SOG A;  1X03 A;  3LLL A;  4H8S A;  4WPC A;  3HAH A;  3OK8 A;  4DCN C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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