2KMGA

The structure of the klca and ardb proteins show a novel fold and antirestriction activity against type i dna restriction systems in vivo but not in vitro
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
142
structure length
142
Chain Sequence
MNTEEQPVTASLVAEAQRLDFLPTYFGPRLMMRGEALVYAWMRRLCERYNGAYWHYYALSDGGFYMAPDLAGRLEIEVNGNGFRGELSADAAGIVATLFALGQLAAEIADTDAADALIDRYHFLRGFAAGHPEAAAIYRAID
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of the KlcA and ArdB proteins reveals a novel fold and antirestriction activity against Type I DNA restriction systems in vivo but not in vitro
pubmed doi rcsb
molecule tags Gene regulation
source organism Bordetella pertussis
molecule keywords KlcA
total genus 31
structure length 142
sequence length 142
ec nomenclature
pdb deposition date 2009-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03230 Antirestrict Antirestriction protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.472.120 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin A; domain 1 2kmgA00
2KMGA 2WJ9A
chains in the Genus database with same CATH superfamily
2UZBB 4ZGJB 4QSHA 3WVEB 4ZGEB 4ROCA 1OI9B 4EONB 4BCOB 2PK2A 2DD4B 1JOWA 3A8GB 3BG5A 2WEVB 4OB2B 4EOPB 2UZEB 4TTHA 4HNUA 1O9KB 2C5XB 1UGPB 2QDJA 4JX6A 4F7JB 3NDQA 1P5EB 2WXVB 4F7NB 4ELJA 1GUXA 4FX3B 4IMYB 2BS3A 1G3NC 4CFUB 4BCQD 4MFEA 2WMAB 1H26B 2DXCB 4NC6A 1VYWB 3X24B 4JX4A 2EUFA 5CEIB 1E7PA 5HNBB 4BCHB 3TW6A 3VYGB 5ICPB 1FINB 3MIAB 3VYHB 5IDNB 3O0GD 1OIUB 5EFQB 2UZDB 3MY5B 2KMGA 4F6SB 1OKWB 2QGSA 4BCND 1H1SB 2CZ6B 1W98B 1UGSB 2WJ9A 3M03A 1ENWA 3QHRB 2ZPFB 5EJCA 1QMZB 4BCMB 3TNIB 4ROEA 3QYBA 1H27B 1URCB 3PO3S 5IDPB 2PJQA 2W9ZA 3DDPB 3A8MB 3F5XB 1AD6A 4CFUD 1UGQB 4EOSB 1UNGD 3TNHB 4MIMA 4BCGB 4KRCB 4F6WB 1OL2B 1PKDB 2DXBB 4EOLB 2ZPBB 2ZPEB 3BLQB 4NSTB 3VKHA 3QZ5B 1H1QB 4BXXX 1VINA 2DPPB 4F6UB 3HHTB 3QYGB 4KRDB 4OB3B 1H28B 4MFDA 3QZ9B 2I40B 1TFBA 1JSTB 2KR6A 4BCMD 4BBRM 5CYIB 4FM4B 2CZ1B 5DQVA 2W2HA 2BPMB 2QQ8A 5IF1B 1V29B 2C5OB 4ELLA 3X25B 2DD5B 1GH6B 3HB9A 4EOMB 3MY1B 3BG9A 2CCHB 4EC9B 2V22B 2ZCFB 1IREB 3KHIA 5LMKB 4OB0B 2D0QB 3X28B 3EJ1B 4EORB 1UGRB 1KXUA 2PMIB 2W9FA 4CRLB 4BCJB 4Z6YA 4RODA 4BBSM 2ZZDB 4JX5A 4AKGA 4OGRB 2C4GB 2QDYB 3DDQB 4CFXB 1GY3B 4G6LB 3MI9B 2C6TB 2W96A 2F2CA 1H25B 3K7AM 5BNJB 2WIHB 1OKVB 2WIPB 2ZPGB 1H1RB 3QXEB 5HQ0B 5HVYB 3DOGB 4OR5B 3DTOA 1OL1B 3B57A 3POMA 3QYEA 3X20B 4OB1B 5I5ZB 3QWLA 5ACBA 4YOOA 2X1NB 3BLHB 4BCQB 4ZGDB 2WHBB 3G33B 4EOIB 3BHVB 2BS2A 2IW8B 4YOSA 3EIDB 2PHGA 1H24B 2R7GA 3HO8A 4HLQA 1ZP2A 2DMEA 2CZ0B 1H1PB 4HNVA 4M6VA 4BCNB 1D3UB 3BHUB 4UN0A 2CJMB 4BCFB 4EOJB 1JSUB 4CFNB 4AI6A 5L2WB 1C9BA 3QHWB 4BCIB 2ZPIB 3DJBA 3A8HB 1UNLD 2G9XB 4F7LB 3BHTB 4EOOB 3BLRB 4BY1X 3BG3A 3X26B 4HNTA 4BCKB 2W99A 3RGFB 4YOZA 3VKGA 2UZLB 4F7SB 5HBJB 2C5NB 3H4CA 4Y72B 3LQ5B 2BKZB 4F70B 2CYZB 3TNWB 4CFMB 5HBEB 1FKMA 4LOCA 4EOQB 3A8LB 1GUXB 2QF7A 1UNHD 2LW4A 5IHYA 4I3ZB 1F5QB 5DQWA 4EOKB 2WPAB 1E9HB 3TW7A 2WFYB 4BY7X 3A8OB 2B9RA 1AISB 1OIYB 3TN8B 2UUEB 3DL1A 1AHJB 2PK9B 5FGKB 4CFVB 1TD6A 2WMBB 1H4LD 2CZ7B 2I53A 4YC3B 3WVDB 1OGUB 2AHJB 4BCPB 3GTMS 1FVVB 1VOLA 3HZJA 4CXAB 2QFZA 4AKHA 4HL4A 4II5B 3HBLA 1JKWA 5LQFB 2CCIB 4AKIA 2ZPHB 2IW9B 1XO2A 2IVXA 2JGZB 2IN3A 4CFWB 4EC8B 1QLBA 2BS4A 2C5VB 3EOCB 3QYHB 5HBHB 2G77A 1O9KA 2IW6B 1N4MA 1BU2A
chains in the Genus database with same CATH topology
4ZGJB 4QSHA 1UGQB 3WVEB 4Z6YA 4ZGEB 4BBSM 3VKGA 2ZZDB 4JX5A 4MIMA 4AKGA 3H4CA 2DD4B 3A8GB 2CYZB 3BG5A 2DXBB 2ZPBB 2ZPEB 4OB2B 3VKHA 2QDYB 3QZ5B 1FKMA 2DPPB 4LOCA 3HHTB 4HNUA 3QYGB 1UGPB 2QDJA 4JX6A 3A8LB 4OB3B 4ELJA 2QF7A 2ZPGB 3QXEB 2BS3A 4MFDA 3QZ9B 3TW7A 2KR6A 3A8OB 4MFEA 3QYEA 3X20B 4BBRM 4OB1B 4FM4B 2CZ1B 2DXCB 4NC6A 3X24B 3QWLA 3DL1A 1AHJB 4JX4A 2QQ8A 1V29B 1E7PA 4ZGDB 3TW6A 3VYGB 2CZ7B 3X25B 2DD5B 3VYHB 2BS2A 3HB9A 3WVDB 2KMGA 3BG9A 2AHJB 3HO8A 4HLQA 2CZ6B 3HZJA 1UGSB 2QFZA 2ZCFB 2WJ9A 2CZ0B 4AKHA 2ZPFB 4HNVA 5EJCA 4M6VA 1IREB 3KHIA 4HL4A 3HBLA 4AKIA 4OB0B 2D0QB 2ZPHB 3X28B 3QYBA 4AI6A 1UGRB 2ZPIB 1QLBA 3A8HB 2BS4A 3QYHB 3BG3A 2G77A 3X26B 3A8MB 4HNTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KMG A;  2WJ9 A; 
#chains in the Genus database with same CATH topology
 2UZB B;  4ZGJ B;  4QSH A;  3WVE B;  4ZGE B;  4ROC A;  1OI9 B;  4EON B;  4BCO B;  2PK2 A;  2DD4 B;  1JOW A;  3A8G B;  3BG5 A;  2WEV B;  4OB2 B;  4EOP B;  2UZE B;  4TTH A;  4HNU A;  1O9K B;  2C5X B;  1UGP B;  2QDJ A;  4JX6 A;  4F7J B;  3NDQ A;  1P5E B;  2WXV B;  4F7N B;  4ELJ A;  1GUX A;  4FX3 B;  4IMY B;  2BS3 A;  1G3N C;  4CFU B;  4BCQ D;  4MFE A;  2WMA B;  1H26 B;  2DXC B;  4NC6 A;  1VYW B;  3X24 B;  4JX4 A;  2EUF A;  5CEI B;  1E7P A;  5HNB B;  4BCH B;  3TW6 A;  3VYG B;  5ICP B;  1FIN B;  3MIA B;  3VYH B;  5IDN B;  3O0G D;  1OIU B;  5EFQ B;  2UZD B;  3MY5 B;  2KMG A;  4F6S B;  1OKW B;  2QGS A;  4BCN D;  1H1S B;  2CZ6 B;  1W98 B;  1UGS B;  2WJ9 A;  3M03 A;  1ENW A;  3QHR B;  2ZPF B;  5EJC A;  1QMZ B;  4BCM B;  3TNI B;  4ROE A;  3QYB A;  1H27 B;  1URC B;  3PO3 S;  5IDP B;  2PJQ A;  2W9Z A;  3DDP B;  3A8M B;  3F5X B;  1AD6 A;  4CFU D;  1UGQ B;  4EOS B;  1UNG D;  3TNH B;  4MIM A;  4BCG B;  4KRC B;  4F6W B;  1OL2 B;  1PKD B;  2DXB B;  4EOL B;  2ZPB B;  2ZPE B;  3BLQ B;  4NST B;  3VKH A;  3QZ5 B;  1H1Q B;  4BXX X;  1VIN A;  2DPP B;  4F6U B;  3HHT B;  3QYG B;  4KRD B;  4OB3 B;  1H28 B;  4MFD A;  3QZ9 B;  2I40 B;  1TFB A;  1JST B;  2KR6 A;  4BCM D;  4BBR M;  5CYI B;  4FM4 B;  2CZ1 B;  5DQV A;  2W2H A;  2BPM B;  2QQ8 A;  5IF1 B;  1V29 B;  2C5O B;  4ELL A;  3X25 B;  2DD5 B;  1GH6 B;  3HB9 A;  4EOM B;  3MY1 B;  3BG9 A;  2CCH B;  4EC9 B;  2V22 B;  2ZCF B;  1IRE B;  3KHI A;  5LMK B;  4OB0 B;  2D0Q B;  3X28 B;  3EJ1 B;  4EOR B;  1UGR B;  1KXU A;  2PMI B;  2W9F A;  4CRL B;  4BCJ B;  4Z6Y A;  4ROD A;  4BBS M;  2ZZD B;  4JX5 A;  4AKG A;  4OGR B;  2C4G B;  2QDY B;  3DDQ B;  4CFX B;  1GY3 B;  4G6L B;  3MI9 B;  2C6T B;  2W96 A;  2F2C A;  1H25 B;  3K7A M;  5BNJ B;  2WIH B;  1OKV B;  2WIP B;  2ZPG B;  1H1R B;  3QXE B;  5HQ0 B;  5HVY B;  3DOG B;  4OR5 B;  3DTO A;  1OL1 B;  3B57 A;  3POM A;  3QYE A;  3X20 B;  4OB1 B;  5I5Z B;  3QWL A;  5ACB A;  4YOO A;  2X1N B;  3BLH B;  4BCQ B;  4ZGD B;  2WHB B;  3G33 B;  4EOI B;  3BHV B;  2BS2 A;  2IW8 B;  4YOS A;  3EID B;  2PHG A;  1H24 B;  2R7G A;  3HO8 A;  4HLQ A;  1ZP2 A;  2DME A;  2CZ0 B;  1H1P B;  4HNV A;  4M6V A;  4BCN B;  1D3U B;  3BHU B;  4UN0 A;  2CJM B;  4BCF B;  4EOJ B;  1JSU B;  4CFN B;  4AI6 A;  5L2W B;  1C9B A;  3QHW B;  4BCI B;  2ZPI B;  3DJB A;  3A8H B;  1UNL D;  2G9X B;  4F7L B;  3BHT B;  4EOO B;  3BLR B;  4BY1 X;  3BG3 A;  3X26 B;  4HNT A;  4BCK B;  2W99 A;  3RGF B;  4YOZ A;  3VKG A;  2UZL B;  4F7S B;  5HBJ B;  2C5N B;  3H4C A;  4Y72 B;  3LQ5 B;  2BKZ B;  4F70 B;  2CYZ B;  3TNW B;  4CFM B;  5HBE B;  1FKM A;  4LOC A;  4EOQ B;  3A8L B;  1GUX B;  2QF7 A;  1UNH D;  2LW4 A;  5IHY A;  4I3Z B;  1F5Q B;  5DQW A;  4EOK B;  2WPA B;  1E9H B;  3TW7 A;  2WFY B;  4BY7 X;  3A8O B;  2B9R A;  1AIS B;  1OIY B;  3TN8 B;  2UUE B;  3DL1 A;  1AHJ B;  2PK9 B;  5FGK B;  4CFV B;  1TD6 A;  2WMB B;  1H4L D;  2CZ7 B;  2I53 A;  4YC3 B;  3WVD B;  1OGU B;  2AHJ B;  4BCP B;  3GTM S;  1FVV B;  1VOL A;  3HZJ A;  4CXA B;  2QFZ A;  4AKH A;  4HL4 A;  4II5 B;  3HBL A;  1JKW A;  5LQF B;  2CCI B;  4AKI A;  2ZPH B;  2IW9 B;  1XO2 A;  2IVX A;  2JGZ B;  2IN3 A;  4CFW B;  4EC8 B;  1QLB A;  2BS4 A;  2C5V B;  3EOC B;  3QYH B;  5HBH B;  2G77 A;  1O9K A;  2IW6 B;  1N4M A;  1BU2 A; 
#chains in the Genus database with same CATH homology
 4ZGJ B;  4QSH A;  1UGQ B;  3WVE B;  4Z6Y A;  4ZGE B;  4BBS M;  3VKG A;  2ZZD B;  4JX5 A;  4MIM A;  4AKG A;  3H4C A;  2DD4 B;  3A8G B;  2CYZ B;  3BG5 A;  2DXB B;  2ZPB B;  2ZPE B;  4OB2 B;  3VKH A;  2QDY B;  3QZ5 B;  1FKM A;  2DPP B;  4LOC A;  3HHT B;  4HNU A;  3QYG B;  1UGP B;  2QDJ A;  4JX6 A;  3A8L B;  4OB3 B;  4ELJ A;  2QF7 A;  2ZPG B;  3QXE B;  2BS3 A;  4MFD A;  3QZ9 B;  3TW7 A;  2KR6 A;  3A8O B;  4MFE A;  3QYE A;  3X20 B;  4BBR M;  4OB1 B;  4FM4 B;  2CZ1 B;  2DXC B;  4NC6 A;  3X24 B;  3QWL A;  3DL1 A;  1AHJ B;  4JX4 A;  2QQ8 A;  1V29 B;  1E7P A;  4ZGD B;  3TW6 A;  3VYG B;  2CZ7 B;  3X25 B;  2DD5 B;  3VYH B;  2BS2 A;  3HB9 A;  3WVD B;  2KMG A;  3BG9 A;  2AHJ B;  3HO8 A;  4HLQ A;  2CZ6 B;  3HZJ A;  1UGS B;  2QFZ A;  2ZCF B;  2WJ9 A;  2CZ0 B;  4AKH A;  2ZPF B;  4HNV A;  5EJC A;  4M6V A;  1IRE B;  3KHI A;  4HL4 A;  3HBL A;  4AKI A;  4OB0 B;  2D0Q B;  2ZPH B;  3X28 B;  3QYB A;  4AI6 A;  1UGR B;  2ZPI B;  1QLB A;  3A8H B;  2BS4 A;  3QYH B;  3BG3 A;  2G77 A;  3X26 B;  3A8M B;  4HNT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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