2X3WA

Structure of mouse syndapin i (crystal form 2)
Total Genus 126
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
126
sequence length
291
structure length
291
Chain Sequence
DSFWEVGNYKRTVKRIDDGHRLCNDLMSCVQERAKIEKAYAQQLTDWAKRWRQLIEKGPQYGSLERAWGAMMTEADKVSELHQEVKNSLLNEDLEKVKNWQKDAYHKQIMGGFKETKEAEDGFRKAQKPWAKKMKELEAAKKAYHLACKEERLAMTREMNSKTEQSVTPEQQKKLVDKVDKCRQDVQKTQEKYEKVLEDVGKTTPQYMEGMEQVFEQCQQFEEKRLVFLKEVLLDIKRHLNLAENSSYMHVYRELEQAIRGADAQEDLRWFRSTSGPGMPMNWPQFEEWNP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular Basis for SH3 Domain Regulation of F-Bar-Mediated Membrane Deformation.
pubmed doi rcsb
molecule tags Endocytosis
source organism Mus musculus
molecule keywords PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROT
total genus 126
structure length 291
sequence length 291
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2010-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2x3wA01
2Q12A 2X3VA 4FZSA 2RAJA 3HAIA 3G9GA 2D1LA 2X3XA 2RAIA 3CAZA 2EFKA 3QWEA 3DYTA 2YKTA 4NQIA 2Z0NA 2X3WA 2ELBA 2Z0OA 4BNEA 4WPCA 4AVMA 5C5BA 4NSWA 2RAKA 1Y2OA 5C5BB 3ABHA 3ACOA 3Q0KA 2V0OA 3PLTA 3QNIA 3SYVA 4DCNC 4WPEA 3M3WA 1I4DA 2Z0VA 3LLLA 2D4CA 3SOGA 1X04A 4H8SA 1I4TA 1I4LA 1WDZA 2Q13A 2FICA 1I49A 2EFLA 4DYLA 3Q84A 3HAJA 4ATMA 4AKVA 4I1QA 3HAHA 2C08A 3QE6A 1X03A 3OK8A 1URUA 3I2WA 1ZWWA
chains in the Genus database with same CATH superfamily
1ZYLA 3B53X 3QNJA 3D4YA 3O3OB 1QWNA 3SYVA 3BLBA 3M3WA 1DKXA 3VEAA 2F18A 2GAFD 1SU8A 3KDRA 2QFFA 1SU7A 2PMRA 4R5KA 3DPOA 5C5BA 3ABHA 3DDFA 2O0I1 4EZSA 4HR1A 1E1DA 2QXLA 4PO2A 3D2FA 1O7DB 1R5EA 2YI8A 4EZXA 4E3CA 2RAJA 1UPXA 2X3XA 2OBLA 2Z0OA 2X5CA 4EZVA 3D50A 4KIKB 3A98A 4R5JA 4JWDA 2ZXQA 3D52A 2JNSA 3UITA 5KBPA 3HAHA 3I2WA 3LVTA 3EJUA 2D1LA 3D2EA 2EWFA 3DPPA 1GN9A 4IWOA 4JWIA 4JLCA 3SOGA 4B9QA 1I4TA 3EJRA 1W9MA 2EFLA 4JNFA 2F1AA 2F1BA 4JWEA 4FM3A 3D4ZA 2V0OA 3PLTA 4IM3A 2Z8YA 3O3NB 2YLAA 1HWWA 2QKWA 1I4LA 3T4AG 1URUA 3DX2A 1TQTA 3DYTA 3BVVA 3T46A 1OA1A 3ZEDA 4KIKA 1I4DA 1E2UA 3BUBA 1JQKA 3HAJA 2YL9A 1ZWWA 4NPHA 2OO2A 2Q12A 2OW6A 3DX0A 4E81A 1HXKA 3QNIA 3F7WA 3I04A 3CZNA 3DPQA 3CZSA 2D4CA 4AZHA 3RPMA 2EX3B 2YLLA 3KAWA 3ER8C 1I49A 3C7NA 4I1QA 3OK8A 2RAIA 1QX1A 1LQ7A 2NCZA 2YL6A 1OA0A 2F7RA 1TQVA 4IM2A 5E84A 3CV5A 4H6HA 2F7QA 3LLLA 4H6IA 4UDXX 1HTYA 4DYLA 4M0MA 1GNLA 3T49A 3HAIA 4AZGA 5FLEX 2JNKA 3Q0KA 2YIVX 1TQUA 3T47A 2OW7A 3LMFA 2FYVA 4R5IA 3DDGA 4HYBA 4F00A 4AZIA 3FD9A 1DKZA 4D8JA 3QE6A 4FZSA 3RV0A 2RT6A 2X3WA 4NSWA 4BNEA 1Y2OA 4EZUA 4FZPA 4DCNC 4EZNA 2PY6A 3CKDA 3BVXA 1TQWA 4IWQA 4AZCB 2WINM 2ND0A 2GA9D 1PS3A 3BUIA 2YL5A 3GI7A 4EZQA 3ER9B 1R34A 4AZ5A 2ALWA 4HY9A 4EZRA 4JNEA 4JL9A 4AKVA 1U00A 1TQSA 4H8SA 4G6QA 2YL8A 4IWPA 4NQIA 3O3MB 2ELBA 4AVMA 4WPEA 1OAOA 3ACOA 4AZ7A 3VKHA 4R5GA 1QWUA 3BVUA 1SUFA 4IM0A 3BVWA 2GF4A 1DKYA 2C08A 3I39X 3B51X 3I01A 3OHXM 3L3OM 5FIGA 3D51A 4F01A 4AZ6A 1GNTA 2OZNB 3BUDA 1WDZA 3OWGA 2F7PA 4AZCA 4ATMA 4JWCA 4UDYX 1X03A 4EZYA 2YIBA 2LXYA 1O7DC 3DX1A 2Z0NA 3BUQA 2WYHA 2WYIA 4EZTA 2Z0VA 4EZZA 4IW0A 1X04A 3KAVA 4JN4A 4EZOA 1YWMA 2N3KA 3BUPA 2X3VA 3G9GA 3L3PA 3QWEA 3RV1A 2LM0A 3VEBA 4WPCA 5C5BB 1E9VA 3EJTA 4EZPA 4HR1B 4EZWA 2FICA 2Q13A 4AZBA 2YI9A 1R33A 2ND1A 3EJQA 3EJSA 3ERCC 3EJPA 3DX4A 3CAZA 2EFKA 3DX3A 2YKTA 2OBMA 3BVTA 2KHOA 2RAKA 4R5LA 3T48A 5TKYA 2F7OA 2YIAA 4FZOA 2MI7A 3CVRA 1SU6A 3Q84A 3B52X 1MJGA 3QA8A
chains in the Genus database with same CATH topology
2Q12A 2X3VA 4FZSA 2RAJA 3HAIA 3G9GA 2D1LA 2X3XA 2RAIA 3CAZA 2EFKA 3QWEA 3DYTA 2YKTA 4NQIA 2Z0NA 2X3WA 2ELBA 2Z0OA 4BNEA 4WPCA 4AVMA 5C5BA 4NSWA 2RAKA 1Y2OA 5C5BB 3ABHA 3ACOA 3Q0KA 2V0OA 3PLTA 3QNIA 3SYVA 4DCNC 4WPEA 3M3WA 1I4DA 2Z0VA 3LLLA 2D4CA 3SOGA 1X04A 4H8SA 1I4TA 1I4LA 1WDZA 2Q13A 2FICA 1I49A 2EFLA 4DYLA 3Q84A 3HAJA 4ATMA 4AKVA 4I1QA 3HAHA 2C08A 3QE6A 1X03A 3OK8A 1URUA 3I2WA 1ZWWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Q12 A;  2X3V A;  4FZS A;  2RAJ A;  3HAI A;  3G9G A;  2D1L A;  2X3X A;  2RAI A;  3CAZ A;  2EFK A;  3QWE A;  3DYT A;  2YKT A;  4NQI A;  2Z0N A;  2X3W A;  2ELB A;  2Z0O A;  4BNE A;  4WPC A;  4AVM A;  5C5B A;  4NSW A;  2RAK A;  1Y2O A;  5C5B B;  3ABH A;  3ACO A;  3Q0K A;  2V0O A;  3PLT A;  3QNI A;  3SYV A;  4DCN C;  4WPE A;  3M3W A;  1I4D A;  2Z0V A;  3LLL A;  2D4C A;  3SOG A;  1X04 A;  4H8S A;  1I4T A;  1I4L A;  1WDZ A;  2Q13 A;  2FIC A;  1I49 A;  2EFL A;  4DYL A;  3Q84 A;  3HAJ A;  4ATM A;  4AKV A;  4I1Q A;  3HAH A;  2C08 A;  3QE6 A;  1X03 A;  3OK8 A;  1URU A;  3I2W A;  1ZWW A; 
#chains in the Genus database with same CATH topology
 1ZYL A;  3B53 X;  3QNJ A;  3D4Y A;  3O3O B;  1QWN A;  3SYV A;  3BLB A;  3M3W A;  1DKX A;  3VEA A;  2F18 A;  2GAF D;  1SU8 A;  3KDR A;  2QFF A;  1SU7 A;  2PMR A;  4R5K A;  3DPO A;  5C5B A;  3ABH A;  3DDF A;  2O0I 1;  4EZS A;  4HR1 A;  1E1D A;  2QXL A;  4PO2 A;  3D2F A;  1O7D B;  1R5E A;  2YI8 A;  4EZX A;  4E3C A;  2RAJ A;  1UPX A;  2X3X A;  2OBL A;  2Z0O A;  2X5C A;  4EZV A;  3D50 A;  4KIK B;  3A98 A;  4R5J A;  4JWD A;  2ZXQ A;  3D52 A;  2JNS A;  3UIT A;  5KBP A;  3HAH A;  3I2W A;  3LVT A;  3EJU A;  2D1L A;  3D2E A;  2EWF A;  3DPP A;  1GN9 A;  4IWO A;  4JWI A;  4JLC A;  3SOG A;  4B9Q A;  1I4T A;  3EJR A;  1W9M A;  2EFL A;  4JNF A;  2F1A A;  2F1B A;  4JWE A;  4FM3 A;  3D4Z A;  2V0O A;  3PLT A;  4IM3 A;  2Z8Y A;  3O3N B;  2YLA A;  1HWW A;  2QKW A;  1I4L A;  3T4A G;  1URU A;  3DX2 A;  1TQT A;  3DYT A;  3BVV A;  3T46 A;  1OA1 A;  3ZED A;  4KIK A;  1I4D A;  1E2U A;  3BUB A;  1JQK A;  3HAJ A;  2YL9 A;  1ZWW A;  4NPH A;  2OO2 A;  2Q12 A;  2OW6 A;  3DX0 A;  4E81 A;  1HXK A;  3QNI A;  3F7W A;  3I04 A;  3CZN A;  3DPQ A;  3CZS A;  2D4C A;  4AZH A;  3RPM A;  2EX3 B;  2YLL A;  3KAW A;  3ER8 C;  1I49 A;  3C7N A;  4I1Q A;  3OK8 A;  2RAI A;  1QX1 A;  1LQ7 A;  2NCZ A;  2YL6 A;  1OA0 A;  2F7R A;  1TQV A;  4IM2 A;  5E84 A;  3CV5 A;  4H6H A;  2F7Q A;  3LLL A;  4H6I A;  4UDX X;  1HTY A;  4DYL A;  4M0M A;  1GNL A;  3T49 A;  3HAI A;  4AZG A;  5FLE X;  2JNK A;  3Q0K A;  2YIV X;  1TQU A;  3T47 A;  2OW7 A;  3LMF A;  2FYV A;  4R5I A;  3DDG A;  4HYB A;  4F00 A;  4AZI A;  3FD9 A;  1DKZ A;  4D8J A;  3QE6 A;  4FZS A;  3RV0 A;  2RT6 A;  2X3W A;  4NSW A;  4BNE A;  1Y2O A;  4EZU A;  4FZP A;  4DCN C;  4EZN A;  2PY6 A;  3CKD A;  3BVX A;  1TQW A;  4IWQ A;  4AZC B;  2WIN M;  2ND0 A;  2GA9 D;  1PS3 A;  3BUI A;  2YL5 A;  3GI7 A;  4EZQ A;  3ER9 B;  1R34 A;  4AZ5 A;  2ALW A;  4HY9 A;  4EZR A;  4JNE A;  4JL9 A;  4AKV A;  1U00 A;  1TQS A;  4H8S A;  4G6Q A;  2YL8 A;  4IWP A;  4NQI A;  3O3M B;  2ELB A;  4AVM A;  4WPE A;  1OAO A;  3ACO A;  4AZ7 A;  3VKH A;  4R5G A;  1QWU A;  3BVU A;  1SUF A;  4IM0 A;  3BVW A;  2GF4 A;  1DKY A;  2C08 A;  3I39 X;  3B51 X;  3I01 A;  3OHX M;  3L3O M;  5FIG A;  3D51 A;  4F01 A;  4AZ6 A;  1GNT A;  2OZN B;  3BUD A;  1WDZ A;  3OWG A;  2F7P A;  4AZC A;  4ATM A;  4JWC A;  4UDY X;  1X03 A;  4EZY A;  2YIB A;  2LXY A;  1O7D C;  3DX1 A;  2Z0N A;  3BUQ A;  2WYH A;  2WYI A;  4EZT A;  2Z0V A;  4EZZ A;  4IW0 A;  1X04 A;  3KAV A;  4JN4 A;  4EZO A;  1YWM A;  2N3K A;  3BUP A;  2X3V A;  3G9G A;  3L3P A;  3QWE A;  3RV1 A;  2LM0 A;  3VEB A;  4WPC A;  5C5B B;  1E9V A;  3EJT A;  4EZP A;  4HR1 B;  4EZW A;  2FIC A;  2Q13 A;  4AZB A;  2YI9 A;  1R33 A;  2ND1 A;  3EJQ A;  3EJS A;  3ERC C;  3EJP A;  3DX4 A;  3CAZ A;  2EFK A;  3DX3 A;  2YKT A;  2OBM A;  3BVT A;  2KHO A;  2RAK A;  4R5L A;  3T48 A;  5TKY A;  2F7O A;  2YIA A;  4FZO A;  2MI7 A;  3CVR A;  1SU6 A;  3Q84 A;  3B52 X;  1MJG A;  3QA8 A; 
#chains in the Genus database with same CATH homology
 2Q12 A;  2X3V A;  4FZS A;  2RAJ A;  3HAI A;  3G9G A;  2D1L A;  2X3X A;  2RAI A;  3CAZ A;  2EFK A;  3QWE A;  3DYT A;  2YKT A;  4NQI A;  2Z0N A;  2X3W A;  2ELB A;  2Z0O A;  4BNE A;  4WPC A;  4AVM A;  5C5B A;  4NSW A;  2RAK A;  1Y2O A;  5C5B B;  3ABH A;  3ACO A;  3Q0K A;  2V0O A;  3PLT A;  3QNI A;  3SYV A;  4DCN C;  4WPE A;  3M3W A;  1I4D A;  2Z0V A;  3LLL A;  2D4C A;  3SOG A;  1X04 A;  4H8S A;  1I4T A;  1I4L A;  1WDZ A;  2Q13 A;  2FIC A;  1I49 A;  2EFL A;  4DYL A;  3Q84 A;  3HAJ A;  4ATM A;  4AKV A;  4I1Q A;  3HAH A;  2C08 A;  3QE6 A;  1X03 A;  3OK8 A;  1URU A;  3I2W A;  1ZWW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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