2X3XA

Structure of mouse syndapin i (crystal form 1)
Total Genus 112
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
291
structure length
291
Chain Sequence
DSFWEVGNYKRTVKRIDDGHRLCNDLMSCVQERAKIEKAYAQQLTDWAKRWRQLIEKGPQYGSLERAWGAMMTEADKVSELHQEVKNSLLNEDLEKVKNWQKDAYHKQIMGGFKETKEAEDGFRKAQKPWAKKMKELEAAKKAYHLACKEERLAMTREMNSKTEQSVTPEQQKKLVDKVDKCRQDVQKTQEKYEKVLEDVGKTTPQYMEGMEQVFEQCQQFEEKRLVFLKEVLLDIKRHLNLAENSSYMHVYRELEQAIRGADAQEDLRWFRSTSGPGMPMNWPQFEEWNP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular Basis for SH3 Domain Regulation of F-Bar-Mediated Membrane Deformation.
pubmed doi rcsb
molecule tags Endocytosis
source organism Mus musculus
molecule keywords PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROT
total genus 112
structure length 291
sequence length 291
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2010-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2x3xA01
2Z0NA 1X04A 3ABHA 4H8SA 2X3VA 2X3WA 1ZWWA 3G9GA 3QNIA 3OK8A 4ATMA 2ELBA 3SYVA 2D4CA 4DYLA 3DYTA 4NQIA 3HAIA 3HAJA 3ACOA 2D1LA 1Y2OA 2EFLA 3QWEA 5C5BB 1I4DA 3QE6A 2FICA 4FZSA 1I4LA 2V0OA 2RAKA 1I4TA 1WDZA 2RAIA 2C08A 4NSWA 2Q13A 3PLTA 5C5BA 3CAZA 1X03A 4AKVA 4AVMA 4BNEA 3Q84A 4DCNC 2YKTA 2Z0OA 1I49A 2EFKA 2X3XA 3M3WA 4WPCA 3SOGA 2Z0VA 3LLLA 2Q12A 3HAHA 3I2WA 3Q0KA 2RAJA 4I1QA 1URUA 4WPEA
chains in the Genus database with same CATH superfamily
1X04A 3ERCC 1O7DB 2YL6A 3UITA 3I39X 2OW7A 3KDRA 2GA9D 2X3XA 3RV0A 2N3KA 4E3CA 3HAJA 3OHXM 1YWMA 1U00A 2YI9A 4HR1B 4IM0A 3L3PA 4AKVA 2KHOA 4EZZA 4AZIA 4KIKA 3M3WA 2WINM 3F7WA 4UDXX 1OA1A 2EX3B 3L3OM 2ND1A 4JN4A 2RT6A 2Z8YA 2MI7A 3EJSA 4AZCB 4AZ7A 2RAIA 3BUIA 2FYVA 4AZ6A 1GNTA 3B51X 3BUPA 3BUDA 4H6HA 3QWEA 2OBMA 2YL5A 4EZYA 3G9GA 2YL9A 4JWDA 1JQKA 4NQIA 2FICA 1SU8A 4R5LA 2Q13A 3T4AG 3QA8A 2ALWA 2EWFA 3BUQA 5E84A 3C7NA 4R5GA 4JNEA 3BVUA 3VEAA 3I04A 1Y2OA 1E9VA 2GAFD 3D4ZA 1HWWA 2F1BA 2C08A 2F7QA 1HXKA 3A98A 1TQVA 1QWNA 2Z0VA 1E2UA 3Q0KA 3DDGA 1GNLA 2X3WA 2F7OA 3SYVA 4EZTA 3ACOA 1UPXA 5C5BB 2YIAA 2F18A 1I4LA 2RAKA 4EZNA 1W9MA 2O0I1 2YI8A 3BVTA 2X3VA 3QNIA 3BVXA 3BUBA 4F00A 5KBPA 1OA0A 3O3MB 2ND0A 3PLTA 5TKYA 2YLLA 3Q84A 4AZ5A 4EZSA 1DKXA 4JWIA 3QE6A 2QKWA 5FIGA 1ZWWA 3OK8A 4D8JA 3EJQA 2GF4A 3T46A 3D51A 1TQUA 2OZNB 2LM0A 4M0MA 3LMFA 1R33A 3DX3A 3ER9B 4IM2A 3KAWA 3CV5A 4UDYX 4R5IA 3B53X 3DDFA 3CZSA 2D4CA 4EZUA 1DKYA 3EJRA 2JNKA 1TQSA 4HR1A 2QXLA 4JLCA 4EZQA 2YKTA 3D50A 2RAJA 4I1QA 3DX0A 2Z0NA 2QFFA 3DPQA 3T47A 4AZGA 3QNJA 1QX1A 1I4TA 3D2EA 1R34A 1DKZA 4HYBA 1SU7A 4AZCA 4EZVA 4IW0A 1SUFA 4H6IA 4AZHA 3BVWA 3T49A 3DX2A 1GN9A 2PY6A 3HAIA 2D1LA 3DPPA 1E1DA 2X5CA 3D4YA 2F1AA 3DX4A 4JWCA 3CKDA 4KIKB 2ZXQA 2Z0OA 2EFKA 4IWQA 5FLEX 3LLLA 1OAOA 3HAHA 1URUA 2YLAA 3ZEDA 1MJGA 3BLBA 4AZBA 4EZRA 3RPMA 4EZPA 1QWUA 1X03A 2OBLA 4EZXA 3T48A 1SU6A 3O3NB 3CVRA 4IWPA 4FM3A 4R5KA 2NCZA 3I2WA 4WPEA 4NPHA 3GI7A 4FZSA 3ER8C 5C5BA 4E81A 2F7PA 4BNEA 3BVVA 2YIVX 1I49A 4HY9A 3FD9A 1HTYA 2EFLA 2YIBA 3DX1A 3EJUA 4R5JA 1I4DA 3B52X 3D52A 2V0OA 1WDZA 4PO2A 4EZOA 4IWOA 4JWEA 3DPOA 3EJPA 3VKHA 3ABHA 3LVTA 1LQ7A 4IM3A 2ELBA 2YL8A 2WYHA 1TQTA 2JNSA 3I01A 3EJTA 2PMRA 1R5EA 1O7DC 3KAVA 1ZYLA 4NSWA 2F7RA 3VEBA 4AVMA 2LXYA 4G6QA 4DCNC 4JL9A 3RV1A 3D2FA 4FZPA 2OW6A 4H8SA 2WYIA 4EZWA 4JNFA 4ATMA 4DYLA 3DYTA 3OWGA 2OO2A 4FZOA 3CZNA 1TQWA 4B9QA 3CAZA 3O3OB 4F01A 1PS3A 3SOGA 4WPCA 2Q12A
chains in the Genus database with same CATH topology
2Z0NA 1X04A 3ABHA 4H8SA 2X3VA 2X3WA 1ZWWA 3G9GA 3QNIA 3OK8A 4ATMA 2ELBA 3SYVA 2D4CA 4DYLA 3DYTA 4NQIA 3HAIA 3HAJA 3ACOA 2D1LA 1Y2OA 2EFLA 3QWEA 5C5BB 1I4DA 3QE6A 2FICA 4FZSA 1I4LA 2V0OA 2RAKA 1I4TA 1WDZA 2RAIA 2C08A 4NSWA 2Q13A 3PLTA 5C5BA 3CAZA 1X03A 4AKVA 4AVMA 4BNEA 3Q84A 4DCNC 2YKTA 2Z0OA 1I49A 2EFKA 2X3XA 3M3WA 4WPCA 3SOGA 2Z0VA 3LLLA 2Q12A 3HAHA 3I2WA 3Q0KA 2RAJA 4I1QA 1URUA 4WPEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Z0N A;  1X04 A;  3ABH A;  4H8S A;  2X3V A;  2X3W A;  1ZWW A;  3G9G A;  3QNI A;  3OK8 A;  4ATM A;  2ELB A;  3SYV A;  2D4C A;  4DYL A;  3DYT A;  4NQI A;  3HAI A;  3HAJ A;  3ACO A;  2D1L A;  1Y2O A;  2EFL A;  3QWE A;  5C5B B;  1I4D A;  3QE6 A;  2FIC A;  4FZS A;  1I4L A;  2V0O A;  2RAK A;  1I4T A;  1WDZ A;  2RAI A;  2C08 A;  4NSW A;  2Q13 A;  3PLT A;  5C5B A;  3CAZ A;  1X03 A;  4AKV A;  4AVM A;  4BNE A;  3Q84 A;  4DCN C;  2YKT A;  2Z0O A;  1I49 A;  2EFK A;  2X3X A;  3M3W A;  4WPC A;  3SOG A;  2Z0V A;  3LLL A;  2Q12 A;  3HAH A;  3I2W A;  3Q0K A;  2RAJ A;  4I1Q A;  1URU A;  4WPE A; 
#chains in the Genus database with same CATH topology
 1X04 A;  3ERC C;  1O7D B;  2YL6 A;  3UIT A;  3I39 X;  2OW7 A;  3KDR A;  2GA9 D;  2X3X A;  3RV0 A;  2N3K A;  4E3C A;  3HAJ A;  3OHX M;  1YWM A;  1U00 A;  2YI9 A;  4HR1 B;  4IM0 A;  3L3P A;  4AKV A;  2KHO A;  4EZZ A;  4AZI A;  4KIK A;  3M3W A;  2WIN M;  3F7W A;  4UDX X;  1OA1 A;  2EX3 B;  3L3O M;  2ND1 A;  4JN4 A;  2RT6 A;  2Z8Y A;  2MI7 A;  3EJS A;  4AZC B;  4AZ7 A;  2RAI A;  3BUI A;  2FYV A;  4AZ6 A;  1GNT A;  3B51 X;  3BUP A;  3BUD A;  4H6H A;  3QWE A;  2OBM A;  2YL5 A;  4EZY A;  3G9G A;  2YL9 A;  4JWD A;  1JQK A;  4NQI A;  2FIC A;  1SU8 A;  4R5L A;  2Q13 A;  3T4A G;  3QA8 A;  2ALW A;  2EWF A;  3BUQ A;  5E84 A;  3C7N A;  4R5G A;  4JNE A;  3BVU A;  3VEA A;  3I04 A;  1Y2O A;  1E9V A;  2GAF D;  3D4Z A;  1HWW A;  2F1B A;  2C08 A;  2F7Q A;  1HXK A;  3A98 A;  1TQV A;  1QWN A;  2Z0V A;  1E2U A;  3Q0K A;  3DDG A;  1GNL A;  2X3W A;  2F7O A;  3SYV A;  4EZT A;  3ACO A;  1UPX A;  5C5B B;  2YIA A;  2F18 A;  1I4L A;  2RAK A;  4EZN A;  1W9M A;  2O0I 1;  2YI8 A;  3BVT A;  2X3V A;  3QNI A;  3BVX A;  3BUB A;  4F00 A;  5KBP A;  1OA0 A;  3O3M B;  2ND0 A;  3PLT A;  5TKY A;  2YLL A;  3Q84 A;  4AZ5 A;  4EZS A;  1DKX A;  4JWI A;  3QE6 A;  2QKW A;  5FIG A;  1ZWW A;  3OK8 A;  4D8J A;  3EJQ A;  2GF4 A;  3T46 A;  3D51 A;  1TQU A;  2OZN B;  2LM0 A;  4M0M A;  3LMF A;  1R33 A;  3DX3 A;  3ER9 B;  4IM2 A;  3KAW A;  3CV5 A;  4UDY X;  4R5I A;  3B53 X;  3DDF A;  3CZS A;  2D4C A;  4EZU A;  1DKY A;  3EJR A;  2JNK A;  1TQS A;  4HR1 A;  2QXL A;  4JLC A;  4EZQ A;  2YKT A;  3D50 A;  2RAJ A;  4I1Q A;  3DX0 A;  2Z0N A;  2QFF A;  3DPQ A;  3T47 A;  4AZG A;  3QNJ A;  1QX1 A;  1I4T A;  3D2E A;  1R34 A;  1DKZ A;  4HYB A;  1SU7 A;  4AZC A;  4EZV A;  4IW0 A;  1SUF A;  4H6I A;  4AZH A;  3BVW A;  3T49 A;  3DX2 A;  1GN9 A;  2PY6 A;  3HAI A;  2D1L A;  3DPP A;  1E1D A;  2X5C A;  3D4Y A;  2F1A A;  3DX4 A;  4JWC A;  3CKD A;  4KIK B;  2ZXQ A;  2Z0O A;  2EFK A;  4IWQ A;  5FLE X;  3LLL A;  1OAO A;  3HAH A;  1URU A;  2YLA A;  3ZED A;  1MJG A;  3BLB A;  4AZB A;  4EZR A;  3RPM A;  4EZP A;  1QWU A;  1X03 A;  2OBL A;  4EZX A;  3T48 A;  1SU6 A;  3O3N B;  3CVR A;  4IWP A;  4FM3 A;  4R5K A;  2NCZ A;  3I2W A;  4WPE A;  4NPH A;  3GI7 A;  4FZS A;  3ER8 C;  5C5B A;  4E81 A;  2F7P A;  4BNE A;  3BVV A;  2YIV X;  1I49 A;  4HY9 A;  3FD9 A;  1HTY A;  2EFL A;  2YIB A;  3DX1 A;  3EJU A;  4R5J A;  1I4D A;  3B52 X;  3D52 A;  2V0O A;  1WDZ A;  4PO2 A;  4EZO A;  4IWO A;  4JWE A;  3DPO A;  3EJP A;  3VKH A;  3ABH A;  3LVT A;  1LQ7 A;  4IM3 A;  2ELB A;  2YL8 A;  2WYH A;  1TQT A;  2JNS A;  3I01 A;  3EJT A;  2PMR A;  1R5E A;  1O7D C;  3KAV A;  1ZYL A;  4NSW A;  2F7R A;  3VEB A;  4AVM A;  2LXY A;  4G6Q A;  4DCN C;  4JL9 A;  3RV1 A;  3D2F A;  4FZP A;  2OW6 A;  4H8S A;  2WYI A;  4EZW A;  4JNF A;  4ATM A;  4DYL A;  3DYT A;  3OWG A;  2OO2 A;  4FZO A;  3CZN A;  1TQW A;  4B9Q A;  3CAZ A;  3O3O B;  4F01 A;  1PS3 A;  3SOG A;  4WPC A;  2Q12 A; 
#chains in the Genus database with same CATH homology
 2Z0N A;  1X04 A;  3ABH A;  4H8S A;  2X3V A;  2X3W A;  1ZWW A;  3G9G A;  3QNI A;  3OK8 A;  4ATM A;  2ELB A;  3SYV A;  2D4C A;  4DYL A;  3DYT A;  4NQI A;  3HAI A;  3HAJ A;  3ACO A;  2D1L A;  1Y2O A;  2EFL A;  3QWE A;  5C5B B;  1I4D A;  3QE6 A;  2FIC A;  4FZS A;  1I4L A;  2V0O A;  2RAK A;  1I4T A;  1WDZ A;  2RAI A;  2C08 A;  4NSW A;  2Q13 A;  3PLT A;  5C5B A;  3CAZ A;  1X03 A;  4AKV A;  4AVM A;  4BNE A;  3Q84 A;  4DCN C;  2YKT A;  2Z0O A;  1I49 A;  2EFK A;  2X3X A;  3M3W A;  4WPC A;  3SOG A;  2Z0V A;  3LLL A;  2Q12 A;  3HAH A;  3I2W A;  3Q0K A;  2RAJ A;  4I1Q A;  1URU A;  4WPE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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