3ABHA

Crystal structure of the efc/f-bar domain of human pacsin2/syndapin ii (2.0 a)
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
288
structure length
288
Chain Sequence
DSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQFEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mapping of the basic amino-acid residues responsible for tubulation and cellular protrusion by the EFC/F-BAR domain of pacsin2/Syndapin II
pubmed doi rcsb
molecule tags Endocytosis
source organism Homo sapiens
molecule keywords Protein kinase C and casein kinase substrate in neurons prot
total genus 114
structure length 288
sequence length 288
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-12-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3abhA01
4I1QA 1I49A 3M3WA 2EFLA 5C5BA 4DCNC 3LLLA 3HAJA 3QWEA 4WPEA 1I4DA 2Z0NA 1I4LA 3HAIA 3Q84A 2Q12A 2C08A 2Z0OA 2V0OA 3SOGA 3G9GA 3PLTA 3QE6A 2X3XA 1X04A 2X3WA 2Z0VA 3ABHA 2D1LA 4BNEA 3I2WA 4NSWA 1WDZA 3HAHA 4NQIA 2FICA 3DYTA 4DYLA 2EFKA 3ACOA 5C5BB 3Q0KA 1X03A 4AKVA 3SYVA 1URUA 3OK8A 1Y2OA 1I4TA 2ELBA 2YKTA 4WPCA 4H8SA 1ZWWA 3CAZA 2RAKA 4ATMA 2RAIA 4FZSA 2RAJA 3QNIA 2D4CA 4AVMA 2Q13A 2X3VA
chains in the Genus database with same CATH superfamily
5C5BA 3DPPA 3F7WA 1TQTA 2V0OA 4JWIA 2EWFA 1PS3A 4HYBA 2D1LA 1DKXA 4JWDA 3OK8A 3T4AG 4IWPA 2JNKA 3O3NB 3HAJA 3OWGA 3Q84A 2C08A 3DX4A 3QE6A 4EZRA 4HR1B 2F18A 4BNEA 4DYLA 4AKVA 3CVRA 3VEAA 4IM2A 1ZWWA 4ATMA 1HTYA 4KIKA 4G6QA 4WPEA 2N3KA 1OA1A 1TQWA 4EZVA 2QXLA 2Q12A 3G9GA 2WINM 3BUPA 2EFKA 5FIGA 3O3MB 1O7DC 1TQVA 1I4TA 5FLEX 3LLLA 3I01A 3BVUA 3DDFA 1TQUA 3PLTA 1X04A 2YL5A 2F7PA 1LQ7A 2OZNB 4D8JA 1YWMA 3ER8C 2ELBA 4WPCA 2EX3B 1E2UA 4EZXA 2OW6A 3CV5A 1I49A 4AZHA 4DCNC 3D52A 3QWEA 2YIVX 2ND1A 3I04A 4AZCB 3D2FA 5C5BB 1Y2OA 2YKTA 2QKWA 2RAJA 1W9MA 3D4YA 4H6IA 4EZUA 2NCZA 3T49A 3DX1A 3VKHA 2X3WA 4UDYX 2QFFA 2GA9D 4F01A 3QNJA 2RAIA 3GI7A 2GF4A 3L3PA 3CZNA 2Z8YA 4AZ7A 4IM0A 4KIKB 3HAHA 4FZPA 3T48A 3ZEDA 2YIAA 1X03A 2MI7A 3EJUA 2D4CA 2Q13A 3LVTA 3CZSA 3D4ZA 4H6HA 5E84A 2YIBA 1R33A 3BUQA 3SOGA 1GN9A 1WDZA 2YI8A 3B51X 3RPMA 4IWQA 4NQIA 4B9QA 3Q0KA 3FD9A 2X5CA 3EJTA 3QNIA 1SU7A 4I1QA 3EJSA 2PMRA 2JNSA 2YLLA 3DX0A 3BVVA 3BUIA 3QA8A 2X3XA 3EJPA 2OW7A 3ACOA 4PO2A 4JWCA 4R5LA 4AVMA 2F7QA 2YL8A 2Z0NA 3EJQA 3A98A 4R5GA 2Z0OA 1QWUA 4IWOA 2YI9A 4JLCA 1R34A 2ALWA 3CKDA 3DDGA 4HY9A 1E1DA 1O7DB 4AZIA 2OO2A 1QWNA 2KHOA 3DPOA 4JL9A 1R5EA 4AZ6A 1HWWA 2YLAA 4AZGA 3VEBA 2YL9A 2F1AA 3ER9B 1OA0A 4IM3A 4AZ5A 3DYTA 3D51A 3B52X 4EZWA 4H8SA 4EZTA 4FM3A 2YL6A 5TKYA 3M3WA 3BUBA 1U00A 2EFLA 2FYVA 2OBMA 4EZZA 2LM0A 1DKZA 2O0I1 1SU6A 1SUFA 3BVXA 3D50A 3OHXM 2WYIA 2RT6A 3C7NA 4IW0A 1OAOA 4EZOA 3EJRA 2WYHA 3L3OM 3CAZA 2LXYA 2RAKA 4FZSA 4EZSA 1TQSA 4F00A 2X3VA 3BVTA 2GAFD 1GNTA 3ABHA 4JWEA 4AZBA 2F7RA 3SYVA 3BVWA 4HR1A 1HXKA 3KDRA 4JNEA 3O3OB 1I4DA 1DKYA 2PY6A 3HAIA 3ERCC 3DX2A 3D2EA 4EZYA 3I2WA 4JNFA 4NSWA 4R5KA 3LMFA 3RV1A 1JQKA 4UDXX 4JN4A 3I39X 1E9VA 2F7OA 3KAWA 1QX1A 1GNLA 1I4LA 3KAVA 1UPXA 4EZPA 1ZYLA 2ND0A 2Z0VA 3T46A 2OBLA 2FICA 3DPQA 3B53X 1URUA 2F1BA 4NPHA 4R5JA 4E81A 3UITA 1MJGA 4R5IA 1SU8A 2ZXQA 4E3CA 5KBPA 4EZQA 3T47A 4EZNA 4M0MA 3BUDA 4AZCA 3RV0A 4FZOA 3DX3A 3BLBA
chains in the Genus database with same CATH topology
4I1QA 1I49A 3M3WA 2EFLA 5C5BA 4DCNC 3LLLA 3HAJA 3QWEA 4WPEA 1I4DA 2Z0NA 1I4LA 3HAIA 3Q84A 2Q12A 2C08A 2Z0OA 2V0OA 3SOGA 3G9GA 3PLTA 3QE6A 2X3XA 1X04A 2X3WA 2Z0VA 3ABHA 2D1LA 4BNEA 3I2WA 4NSWA 1WDZA 3HAHA 4NQIA 2FICA 3DYTA 4DYLA 2EFKA 3ACOA 5C5BB 3Q0KA 1X03A 4AKVA 3SYVA 1URUA 3OK8A 1Y2OA 1I4TA 2ELBA 2YKTA 4WPCA 4H8SA 1ZWWA 3CAZA 2RAKA 4ATMA 2RAIA 4FZSA 2RAJA 3QNIA 2D4CA 4AVMA 2Q13A 2X3VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4I1Q A;  1I49 A;  3M3W A;  2EFL A;  5C5B A;  4DCN C;  3LLL A;  3HAJ A;  3QWE A;  4WPE A;  1I4D A;  2Z0N A;  1I4L A;  3HAI A;  3Q84 A;  2Q12 A;  2C08 A;  2Z0O A;  2V0O A;  3SOG A;  3G9G A;  3PLT A;  3QE6 A;  2X3X A;  1X04 A;  2X3W A;  2Z0V A;  3ABH A;  2D1L A;  4BNE A;  3I2W A;  4NSW A;  1WDZ A;  3HAH A;  4NQI A;  2FIC A;  3DYT A;  4DYL A;  2EFK A;  3ACO A;  5C5B B;  3Q0K A;  1X03 A;  4AKV A;  3SYV A;  1URU A;  3OK8 A;  1Y2O A;  1I4T A;  2ELB A;  2YKT A;  4WPC A;  4H8S A;  1ZWW A;  3CAZ A;  2RAK A;  4ATM A;  2RAI A;  4FZS A;  2RAJ A;  3QNI A;  2D4C A;  4AVM A;  2Q13 A;  2X3V A; 
#chains in the Genus database with same CATH topology
 5C5B A;  3DPP A;  3F7W A;  1TQT A;  2V0O A;  4JWI A;  2EWF A;  1PS3 A;  4HYB A;  2D1L A;  1DKX A;  4JWD A;  3OK8 A;  3T4A G;  4IWP A;  2JNK A;  3O3N B;  3HAJ A;  3OWG A;  3Q84 A;  2C08 A;  3DX4 A;  3QE6 A;  4EZR A;  4HR1 B;  2F18 A;  4BNE A;  4DYL A;  4AKV A;  3CVR A;  3VEA A;  4IM2 A;  1ZWW A;  4ATM A;  1HTY A;  4KIK A;  4G6Q A;  4WPE A;  2N3K A;  1OA1 A;  1TQW A;  4EZV A;  2QXL A;  2Q12 A;  3G9G A;  2WIN M;  3BUP A;  2EFK A;  5FIG A;  3O3M B;  1O7D C;  1TQV A;  1I4T A;  5FLE X;  3LLL A;  3I01 A;  3BVU A;  3DDF A;  1TQU A;  3PLT A;  1X04 A;  2YL5 A;  2F7P A;  1LQ7 A;  2OZN B;  4D8J A;  1YWM A;  3ER8 C;  2ELB A;  4WPC A;  2EX3 B;  1E2U A;  4EZX A;  2OW6 A;  3CV5 A;  1I49 A;  4AZH A;  4DCN C;  3D52 A;  3QWE A;  2YIV X;  2ND1 A;  3I04 A;  4AZC B;  3D2F A;  5C5B B;  1Y2O A;  2YKT A;  2QKW A;  2RAJ A;  1W9M A;  3D4Y A;  4H6I A;  4EZU A;  2NCZ A;  3T49 A;  3DX1 A;  3VKH A;  2X3W A;  4UDY X;  2QFF A;  2GA9 D;  4F01 A;  3QNJ A;  2RAI A;  3GI7 A;  2GF4 A;  3L3P A;  3CZN A;  2Z8Y A;  4AZ7 A;  4IM0 A;  4KIK B;  3HAH A;  4FZP A;  3T48 A;  3ZED A;  2YIA A;  1X03 A;  2MI7 A;  3EJU A;  2D4C A;  2Q13 A;  3LVT A;  3CZS A;  3D4Z A;  4H6H A;  5E84 A;  2YIB A;  1R33 A;  3BUQ A;  3SOG A;  1GN9 A;  1WDZ A;  2YI8 A;  3B51 X;  3RPM A;  4IWQ A;  4NQI A;  4B9Q A;  3Q0K A;  3FD9 A;  2X5C A;  3EJT A;  3QNI A;  1SU7 A;  4I1Q A;  3EJS A;  2PMR A;  2JNS A;  2YLL A;  3DX0 A;  3BVV A;  3BUI A;  3QA8 A;  2X3X A;  3EJP A;  2OW7 A;  3ACO A;  4PO2 A;  4JWC A;  4R5L A;  4AVM A;  2F7Q A;  2YL8 A;  2Z0N A;  3EJQ A;  3A98 A;  4R5G A;  2Z0O A;  1QWU A;  4IWO A;  2YI9 A;  4JLC A;  1R34 A;  2ALW A;  3CKD A;  3DDG A;  4HY9 A;  1E1D A;  1O7D B;  4AZI A;  2OO2 A;  1QWN A;  2KHO A;  3DPO A;  4JL9 A;  1R5E A;  4AZ6 A;  1HWW A;  2YLA A;  4AZG A;  3VEB A;  2YL9 A;  2F1A A;  3ER9 B;  1OA0 A;  4IM3 A;  4AZ5 A;  3DYT A;  3D51 A;  3B52 X;  4EZW A;  4H8S A;  4EZT A;  4FM3 A;  2YL6 A;  5TKY A;  3M3W A;  3BUB A;  1U00 A;  2EFL A;  2FYV A;  2OBM A;  4EZZ A;  2LM0 A;  1DKZ A;  2O0I 1;  1SU6 A;  1SUF A;  3BVX A;  3D50 A;  3OHX M;  2WYI A;  2RT6 A;  3C7N A;  4IW0 A;  1OAO A;  4EZO A;  3EJR A;  2WYH A;  3L3O M;  3CAZ A;  2LXY A;  2RAK A;  4FZS A;  4EZS A;  1TQS A;  4F00 A;  2X3V A;  3BVT A;  2GAF D;  1GNT A;  3ABH A;  4JWE A;  4AZB A;  2F7R A;  3SYV A;  3BVW A;  4HR1 A;  1HXK A;  3KDR A;  4JNE A;  3O3O B;  1I4D A;  1DKY A;  2PY6 A;  3HAI A;  3ERC C;  3DX2 A;  3D2E A;  4EZY A;  3I2W A;  4JNF A;  4NSW A;  4R5K A;  3LMF A;  3RV1 A;  1JQK A;  4UDX X;  4JN4 A;  3I39 X;  1E9V A;  2F7O A;  3KAW A;  1QX1 A;  1GNL A;  1I4L A;  3KAV A;  1UPX A;  4EZP A;  1ZYL A;  2ND0 A;  2Z0V A;  3T46 A;  2OBL A;  2FIC A;  3DPQ A;  3B53 X;  1URU A;  2F1B A;  4NPH A;  4R5J A;  4E81 A;  3UIT A;  1MJG A;  4R5I A;  1SU8 A;  2ZXQ A;  4E3C A;  5KBP A;  4EZQ A;  3T47 A;  4EZN A;  4M0M A;  3BUD A;  4AZC A;  3RV0 A;  4FZO A;  3DX3 A;  3BLB A; 
#chains in the Genus database with same CATH homology
 4I1Q A;  1I49 A;  3M3W A;  2EFL A;  5C5B A;  4DCN C;  3LLL A;  3HAJ A;  3QWE A;  4WPE A;  1I4D A;  2Z0N A;  1I4L A;  3HAI A;  3Q84 A;  2Q12 A;  2C08 A;  2Z0O A;  2V0O A;  3SOG A;  3G9G A;  3PLT A;  3QE6 A;  2X3X A;  1X04 A;  2X3W A;  2Z0V A;  3ABH A;  2D1L A;  4BNE A;  3I2W A;  4NSW A;  1WDZ A;  3HAH A;  4NQI A;  2FIC A;  3DYT A;  4DYL A;  2EFK A;  3ACO A;  5C5B B;  3Q0K A;  1X03 A;  4AKV A;  3SYV A;  1URU A;  3OK8 A;  1Y2O A;  1I4T A;  2ELB A;  2YKT A;  4WPC A;  4H8S A;  1ZWW A;  3CAZ A;  2RAK A;  4ATM A;  2RAI A;  4FZS A;  2RAJ A;  3QNI A;  2D4C A;  4AVM A;  2Q13 A;  2X3V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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