3LLLA

Crystal structure of mouse pacsin2 f-bar domain
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
287
structure length
287
Chain Sequence
DSFWEVGNYKRTVKRIDDGHRLCGDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWIAVMSEAERVSELHLEVKASLMNEDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHTACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKDKYEKSLKELDQTTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVASYKTIYRELEQSIKAADAVEDLRWFRANHGPGMAMNWPQFE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A hinge in the distal end of the PACSIN 2 F-BAR domain may contribute to membrane-curvature sensing.
pubmed doi rcsb
molecule tags Endocytosis
source organism Mus musculus
molecule keywords Protein kinase C and casein kinase substrate in neurons prot
total genus 105
structure length 287
sequence length 287
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-01-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3lllA01
2RAIA 1X03A 2D1LA 4ATMA 2Z0OA 3Q84A 4WPCA 2EFKA 4H8SA 3QWEA 3M3WA 3HAIA 4NSWA 4NQIA 3Q0KA 3QNIA 3DYTA 4AKVA 3OK8A 3ABHA 2RAJA 3SYVA 1I4TA 1WDZA 2X3XA 1ZWWA 2C08A 2Q13A 3HAJA 4AVMA 2RAKA 5C5BB 2Z0NA 4DYLA 2D4CA 2FICA 4FZSA 2V0OA 4I1QA 2EFLA 3QE6A 1I49A 2YKTA 2ELBA 3HAHA 3LLLA 4WPEA 4BNEA 2Z0VA 2X3WA 3ACOA 3I2WA 2Q12A 1X04A 4DCNC 1URUA 1I4DA 3CAZA 1I4LA 2X3VA 5C5BA 1Y2OA 3SOGA 3PLTA 3G9GA
chains in the Genus database with same CATH superfamily
2RAIA 5TKYA 4M0MA 4JNFA 2F7OA 3CV5A 3LVTA 3T48A 3BLBA 3T49A 1GNTA 5C5BB 3D52A 3BVTA 2QXLA 4KIKB 1HXKA 3I39X 4JN4A 2OO2A 5KBPA 2OBLA 4IM0A 4HR1B 3Q84A 4E81A 4HY9A 1U00A 2MI7A 2WYIA 2Q13A 1DKZA 3DPQA 1HWWA 3QE6A 4PO2A 2OZNB 3C7NA 4B9QA 3CVRA 3G9GA 2D1LA 3EJQA 3BUPA 3CKDA 4NSWA 3CZSA 3SYVA 1OA1A 4I1QA 2FICA 3O3OB 2EFLA 4FZPA 3DPOA 3DX4A 3D2EA 4EZXA 4R5IA 2EWFA 3FD9A 3PLTA 4KIKA 3HAIA 3DX2A 3Q0KA 3KDRA 2YIVX 2F7PA 2RAKA 4R5KA 4HR1A 2FYVA 4UDXX 4FZSA 1YWMA 2WYHA 2GF4A 4BNEA 4F00A 3ER8C 2YL6A 4R5LA 4JL9A 3BUDA 2YI8A 4AZCA 4JLCA 4ATMA 1QX1A 3M3WA 3EJSA 3ER9B 2X3XA 3HAJA 4AZGA 4EZYA 4DYLA 2ALWA 4AZIA 4EZPA 1OA0A 2F18A 1R34A 3B52X 3QNIA 4AZ6A 1O7DC 2RAJA 2JNSA 3LLLA 2O0I1 2F7RA 2OBMA 2YLLA 3O3NB 3I2WA 4EZZA 3L3OM 2NCZA 2F1AA 3EJUA 2OW7A 2GAFD 4IWOA 4EZWA 2PY6A 3BUIA 4H6HA 1TQTA 1E2UA 3ACOA 3ERCC 4DCNC 2YIBA 1E9VA 2X3VA 4JWIA 4H8SA 2YL5A 2ND1A 1R5EA 3EJRA 3RV0A 4EZRA 1E1DA 4HYBA 3I04A 3D51A 2D4CA 3BUQA 4EZQA 3D4YA 3D4ZA 3T46A 2X3WA 1LQ7A 5C5BA 1X03A 4EZSA 4JWEA 3DYTA 4AKVA 3RPMA 2Z8YA 1I4TA 3VEAA 3EJPA 4IW0A 4WPEA 3O3MB 2N3KA 1HTYA 3VEBA 2GA9D 1Y2OA 2Z0OA 1SU6A 1TQVA 3BVXA 3ZEDA 4R5JA 2ZXQA 1I49A 2YI9A 2OW6A 4IWPA 1I4DA 3QNJA 2ND0A 1OAOA 3DX0A 1PS3A 1GNLA 3DX3A 2RT6A 4WPCA 3UITA 2YL8A 1TQUA 1WDZA 4AVMA 1DKYA 1QWNA 2X5CA 4D8JA 5FLEX 3L3PA 1R33A 4AZ7A 2WINM 3OHXM 4E3CA 3QA8A 2LXYA 1TQWA 4H6IA 2F1BA 4F01A 2YL9A 4JWDA 3GI7A 3EJTA 3HAHA 3CZNA 4IWQA 3B51X 3I01A 4R5GA 4FM3A 2EFKA 4FZOA 1W9MA 2KHOA 3BVUA 4NPHA 3DDFA 3T4AG 2C08A 4AZCB 2V0OA 3D50A 4AZ5A 2ELBA 4G6QA 3BVWA 3DPPA 4JWCA 3DDGA 3BUBA 3LMFA 4AZBA 1URUA 3CAZA 4UDYX 3DX1A 1UPXA 1TQSA 4EZVA 1SUFA 3T47A 2QKWA 2QFFA 4NQIA 3A98A 3OK8A 1JQKA 2Z0NA 1SU7A 4IM2A 1GN9A 2Z0VA 2F7QA 3B53X 2Q12A 5FIGA 4AZHA 1I4LA 1O7DB 2JNKA 3QWEA 1QWUA 4EZTA 3RV1A 3ABHA 4JNEA 3F7WA 4EZNA 3OWGA 2EX3B 1ZYLA 2YKTA 5E84A 1MJGA 2YLAA 3BVVA 4IM3A 2LM0A 3VKHA 2PMRA 2YIAA 1ZWWA 1DKXA 3KAWA 4EZOA 3KAVA 1SU8A 4EZUA 1X04A 3D2FA 3SOGA
chains in the Genus database with same CATH topology
2RAIA 1X03A 2D1LA 4ATMA 2Z0OA 3Q84A 4WPCA 2EFKA 4H8SA 3QWEA 3M3WA 3HAIA 4NSWA 4NQIA 3Q0KA 3QNIA 3DYTA 4AKVA 3OK8A 3ABHA 2RAJA 3SYVA 1I4TA 1WDZA 2X3XA 1ZWWA 2C08A 2Q13A 3HAJA 4AVMA 2RAKA 5C5BB 2Z0NA 4DYLA 2D4CA 2FICA 4FZSA 2V0OA 4I1QA 2EFLA 3QE6A 1I49A 2YKTA 2ELBA 3HAHA 3LLLA 4WPEA 4BNEA 2Z0VA 2X3WA 3ACOA 3I2WA 2Q12A 1X04A 4DCNC 1URUA 1I4DA 3CAZA 1I4LA 2X3VA 5C5BA 1Y2OA 3SOGA 3PLTA 3G9GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RAI A;  1X03 A;  2D1L A;  4ATM A;  2Z0O A;  3Q84 A;  4WPC A;  2EFK A;  4H8S A;  3QWE A;  3M3W A;  3HAI A;  4NSW A;  4NQI A;  3Q0K A;  3QNI A;  3DYT A;  4AKV A;  3OK8 A;  3ABH A;  2RAJ A;  3SYV A;  1I4T A;  1WDZ A;  2X3X A;  1ZWW A;  2C08 A;  2Q13 A;  3HAJ A;  4AVM A;  2RAK A;  5C5B B;  2Z0N A;  4DYL A;  2D4C A;  2FIC A;  4FZS A;  2V0O A;  4I1Q A;  2EFL A;  3QE6 A;  1I49 A;  2YKT A;  2ELB A;  3HAH A;  3LLL A;  4WPE A;  4BNE A;  2Z0V A;  2X3W A;  3ACO A;  3I2W A;  2Q12 A;  1X04 A;  4DCN C;  1URU A;  1I4D A;  3CAZ A;  1I4L A;  2X3V A;  5C5B A;  1Y2O A;  3SOG A;  3PLT A;  3G9G A; 
#chains in the Genus database with same CATH topology
 2RAI A;  5TKY A;  4M0M A;  4JNF A;  2F7O A;  3CV5 A;  3LVT A;  3T48 A;  3BLB A;  3T49 A;  1GNT A;  5C5B B;  3D52 A;  3BVT A;  2QXL A;  4KIK B;  1HXK A;  3I39 X;  4JN4 A;  2OO2 A;  5KBP A;  2OBL A;  4IM0 A;  4HR1 B;  3Q84 A;  4E81 A;  4HY9 A;  1U00 A;  2MI7 A;  2WYI A;  2Q13 A;  1DKZ A;  3DPQ A;  1HWW A;  3QE6 A;  4PO2 A;  2OZN B;  3C7N A;  4B9Q A;  3CVR A;  3G9G A;  2D1L A;  3EJQ A;  3BUP A;  3CKD A;  4NSW A;  3CZS A;  3SYV A;  1OA1 A;  4I1Q A;  2FIC A;  3O3O B;  2EFL A;  4FZP A;  3DPO A;  3DX4 A;  3D2E A;  4EZX A;  4R5I A;  2EWF A;  3FD9 A;  3PLT A;  4KIK A;  3HAI A;  3DX2 A;  3Q0K A;  3KDR A;  2YIV X;  2F7P A;  2RAK A;  4R5K A;  4HR1 A;  2FYV A;  4UDX X;  4FZS A;  1YWM A;  2WYH A;  2GF4 A;  4BNE A;  4F00 A;  3ER8 C;  2YL6 A;  4R5L A;  4JL9 A;  3BUD A;  2YI8 A;  4AZC A;  4JLC A;  4ATM A;  1QX1 A;  3M3W A;  3EJS A;  3ER9 B;  2X3X A;  3HAJ A;  4AZG A;  4EZY A;  4DYL A;  2ALW A;  4AZI A;  4EZP A;  1OA0 A;  2F18 A;  1R34 A;  3B52 X;  3QNI A;  4AZ6 A;  1O7D C;  2RAJ A;  2JNS A;  3LLL A;  2O0I 1;  2F7R A;  2OBM A;  2YLL A;  3O3N B;  3I2W A;  4EZZ A;  3L3O M;  2NCZ A;  2F1A A;  3EJU A;  2OW7 A;  2GAF D;  4IWO A;  4EZW A;  2PY6 A;  3BUI A;  4H6H A;  1TQT A;  1E2U A;  3ACO A;  3ERC C;  4DCN C;  2YIB A;  1E9V A;  2X3V A;  4JWI A;  4H8S A;  2YL5 A;  2ND1 A;  1R5E A;  3EJR A;  3RV0 A;  4EZR A;  1E1D A;  4HYB A;  3I04 A;  3D51 A;  2D4C A;  3BUQ A;  4EZQ A;  3D4Y A;  3D4Z A;  3T46 A;  2X3W A;  1LQ7 A;  5C5B A;  1X03 A;  4EZS A;  4JWE A;  3DYT A;  4AKV A;  3RPM A;  2Z8Y A;  1I4T A;  3VEA A;  3EJP A;  4IW0 A;  4WPE A;  3O3M B;  2N3K A;  1HTY A;  3VEB A;  2GA9 D;  1Y2O A;  2Z0O A;  1SU6 A;  1TQV A;  3BVX A;  3ZED A;  4R5J A;  2ZXQ A;  1I49 A;  2YI9 A;  2OW6 A;  4IWP A;  1I4D A;  3QNJ A;  2ND0 A;  1OAO A;  3DX0 A;  1PS3 A;  1GNL A;  3DX3 A;  2RT6 A;  4WPC A;  3UIT A;  2YL8 A;  1TQU A;  1WDZ A;  4AVM A;  1DKY A;  1QWN A;  2X5C A;  4D8J A;  5FLE X;  3L3P A;  1R33 A;  4AZ7 A;  2WIN M;  3OHX M;  4E3C A;  3QA8 A;  2LXY A;  1TQW A;  4H6I A;  2F1B A;  4F01 A;  2YL9 A;  4JWD A;  3GI7 A;  3EJT A;  3HAH A;  3CZN A;  4IWQ A;  3B51 X;  3I01 A;  4R5G A;  4FM3 A;  2EFK A;  4FZO A;  1W9M A;  2KHO A;  3BVU A;  4NPH A;  3DDF A;  3T4A G;  2C08 A;  4AZC B;  2V0O A;  3D50 A;  4AZ5 A;  2ELB A;  4G6Q A;  3BVW A;  3DPP A;  4JWC A;  3DDG A;  3BUB A;  3LMF A;  4AZB A;  1URU A;  3CAZ A;  4UDY X;  3DX1 A;  1UPX A;  1TQS A;  4EZV A;  1SUF A;  3T47 A;  2QKW A;  2QFF A;  4NQI A;  3A98 A;  3OK8 A;  1JQK A;  2Z0N A;  1SU7 A;  4IM2 A;  1GN9 A;  2Z0V A;  2F7Q A;  3B53 X;  2Q12 A;  5FIG A;  4AZH A;  1I4L A;  1O7D B;  2JNK A;  3QWE A;  1QWU A;  4EZT A;  3RV1 A;  3ABH A;  4JNE A;  3F7W A;  4EZN A;  3OWG A;  2EX3 B;  1ZYL A;  2YKT A;  5E84 A;  1MJG A;  2YLA A;  3BVV A;  4IM3 A;  2LM0 A;  3VKH A;  2PMR A;  2YIA A;  1ZWW A;  1DKX A;  3KAW A;  4EZO A;  3KAV A;  1SU8 A;  4EZU A;  1X04 A;  3D2F A;  3SOG A; 
#chains in the Genus database with same CATH homology
 2RAI A;  1X03 A;  2D1L A;  4ATM A;  2Z0O A;  3Q84 A;  4WPC A;  2EFK A;  4H8S A;  3QWE A;  3M3W A;  3HAI A;  4NSW A;  4NQI A;  3Q0K A;  3QNI A;  3DYT A;  4AKV A;  3OK8 A;  3ABH A;  2RAJ A;  3SYV A;  1I4T A;  1WDZ A;  2X3X A;  1ZWW A;  2C08 A;  2Q13 A;  3HAJ A;  4AVM A;  2RAK A;  5C5B B;  2Z0N A;  4DYL A;  2D4C A;  2FIC A;  4FZS A;  2V0O A;  4I1Q A;  2EFL A;  3QE6 A;  1I49 A;  2YKT A;  2ELB A;  3HAH A;  3LLL A;  4WPE A;  4BNE A;  2Z0V A;  2X3W A;  3ACO A;  3I2W A;  2Q12 A;  1X04 A;  4DCN C;  1URU A;  1I4D A;  3CAZ A;  1I4L A;  2X3V A;  5C5B A;  1Y2O A;  3SOG A;  3PLT A;  3G9G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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