3LLLA

Crystal structure of mouse pacsin2 f-bar domain
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
287
structure length
287
Chain Sequence
DSFWEVGNYKRTVKRIDDGHRLCGDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWIAVMSEAERVSELHLEVKASLMNEDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHTACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKDKYEKSLKELDQTTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVASYKTIYRELEQSIKAADAVEDLRWFRANHGPGMAMNWPQFE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A hinge in the distal end of the PACSIN 2 F-BAR domain may contribute to membrane-curvature sensing.
pubmed doi rcsb
molecule tags Endocytosis
source organism Mus musculus
molecule keywords Protein kinase C and casein kinase substrate in neurons prot
total genus 105
structure length 287
sequence length 287
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-01-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3lllA01
3HAIA 4WPCA 4FZSA 3HAJA 3OK8A 1Y2OA 2Z0VA 2RAJA 3G9GA 1X03A 2X3WA 4I1QA 2Z0NA 2EFLA 1I4TA 3CAZA 3PLTA 3SYVA 3Q0KA 4BNEA 4H8SA 3ABHA 3QNIA 2ELBA 2YKTA 4WPEA 3DYTA 2X3VA 3I2WA 1I4DA 2FICA 3HAHA 4AKVA 1ZWWA 1I49A 2D1LA 2D4CA 2RAKA 2V0OA 1URUA 2X3XA 3Q84A 2RAIA 4NQIA 4AVMA 5C5BB 4DYLA 2Q13A 1X04A 2C08A 3QE6A 1WDZA 2EFKA 4ATMA 5C5BA 1I4LA 3LLLA 3M3WA 4DCNC 4NSWA 3ACOA 3QWEA 2Z0OA 2Q12A 3SOGA
chains in the Genus database with same CATH superfamily
1QWUA 3DPPA 4JNFA 3DX1A 3ERCC 1SU7A 4BNEA 4EZXA 1R33A 1GNLA 2OZNB 3BUBA 2FICA 2GA9D 4AVMA 4EZUA 3ACOA 2YLLA 2PMRA 1YWMA 3Q0KA 4UDYX 2YI8A 3BUIA 2F18A 4EZRA 3OWGA 4IWOA 4E3CA 1E1DA 3BVVA 3HAIA 4FZSA 4JWEA 3T49A 2ELBA 4JWCA 3T46A 1I4DA 5FLEX 3HAHA 4AKVA 5KBPA 1I49A 3BVUA 3A98A 3D51A 2EX3B 1X04A 4R5IA 3VEAA 3ER9B 4IW0A 1DKXA 2GAFD 4WPCA 2X3WA 2ND0A 1I4TA 3OHXM 4B9QA 4EZVA 3BVXA 4AZBA 3EJTA 2OBMA 1URUA 2ALWA 2N3KA 3D4YA 3DDFA 3LVTA 4G6QA 2YL5A 1R34A 3BUDA 3D52A 4JNEA 1Y2OA 2RAJA 3T4AG 1SU8A 3BVWA 2GF4A 1TQWA 2D4CA 5FIGA 3L3PA 2Q13A 4AZHA 4EZPA 3T48A 4EZYA 3RV0A 3DPQA 2D1LA 1HTYA 3DPOA 1TQUA 2WINM 4IM0A 4R5KA 2EWFA 1ZWWA 4IM3A 4R5GA 2F1BA 4IWPA 4FM3A 1WDZA 4R5LA 3EJQA 4JLCA 3KAVA 3EJUA 3HAJA 3D2FA 1TQTA 3EJRA 2YIAA 3DX4A 4EZTA 3QA8A 4EZQA 2RAIA 4KIKB 4AZCB 2LXYA 3CV5A 1E2UA 3O3NB 2Z0OA 1UPXA 1QX1A 1X03A 4HR1B 1JQKA 5E84A 4HYBA 3QNJA 3BLBA 3UITA 3EJPA 2OW7A 2F7OA 4NQIA 3T47A 1SUFA 1W9MA 3LLLA 1U00A 3BUPA 2LM0A 4AZCA 5TKYA 4JWIA 4AZ6A 2WYHA 4HR1A 2ND1A 2ZXQA 3D4ZA 1QWNA 3KDRA 1HXKA 1I4LA 4EZWA 4NSWA 3GI7A 2Q12A 3DX2A 2YLAA 1TQVA 4F01A 3OK8A 2YIVX 2YI9A 2YKTA 1OA1A 3CVRA 3ZEDA 2OBLA 5C5BB 3BVTA 3F7WA 3QE6A 3C7NA 2MI7A 1GN9A 2YL9A 3QWEA 4UDXX 2QFFA 4E81A 2YL8A 3ABHA 3VKHA 4M0MA 1OA0A 4AZ7A 4HY9A 2X3XA 2F1AA 3DX3A 3LMFA 3DX0A 4NPHA 3O3OB 3B53X 2YL6A 5C5BA 3B51X 2O0I1 2QXLA 2OW6A 3I01A 1DKZA 4JN4A 4H6HA 2Z8YA 4AZIA 1LQ7A 1OAOA 2OO2A 2V0OA 4DYLA 1TQSA 2C08A 3CKDA 4EZOA 2FYVA 4D8JA 2F7QA 4PO2A 2Z0VA 1ZYLA 2Z0NA 3CAZA 3I04A 3PLTA 3CZNA 2X3VA 3RPMA 4EZNA 2RAKA 3CZSA 3I39X 2NCZA 2EFKA 2WYIA 1SU6A 2KHOA 4DCNC 3VEBA 3SOGA 4EZZA 1GNTA 4KIKA 3G9GA 4I1QA 1O7DB 4H8SA 3QNIA 3DYTA 3O3MB 3RV1A 3B52X 1HWWA 3L3OM 3M3WA 1E9VA 2F7RA 2F7PA 3FD9A 2JNSA 2X5CA 1PS3A 2EFLA 3SYVA 4FZOA 4JWDA 4JL9A 3ER8C 3I2WA 4FZPA 3KAWA 4AZGA 4IWQA 2PY6A 3DDGA 4AZ5A 4EZSA 3BUQA 4R5JA 4H6IA 1R5EA 4IM2A 1MJGA 2QKWA 2YIBA 3EJSA 4WPEA 3D50A 3Q84A 2JNKA 2RT6A 1DKYA 4ATMA 1O7DC 3D2EA 4F00A
chains in the Genus database with same CATH topology
3HAIA 4WPCA 4FZSA 3HAJA 3OK8A 1Y2OA 2Z0VA 2RAJA 3G9GA 1X03A 2X3WA 4I1QA 2Z0NA 2EFLA 1I4TA 3CAZA 3PLTA 3SYVA 3Q0KA 4BNEA 4H8SA 3ABHA 3QNIA 2ELBA 2YKTA 4WPEA 3DYTA 2X3VA 3I2WA 1I4DA 2FICA 3HAHA 4AKVA 1ZWWA 1I49A 2D1LA 2D4CA 2RAKA 2V0OA 1URUA 2X3XA 3Q84A 2RAIA 4NQIA 4AVMA 5C5BB 4DYLA 2Q13A 1X04A 2C08A 3QE6A 1WDZA 2EFKA 4ATMA 5C5BA 1I4LA 3LLLA 3M3WA 4DCNC 4NSWA 3ACOA 3QWEA 2Z0OA 2Q12A 3SOGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HAI A;  4WPC A;  4FZS A;  3HAJ A;  3OK8 A;  1Y2O A;  2Z0V A;  2RAJ A;  3G9G A;  1X03 A;  2X3W A;  4I1Q A;  2Z0N A;  2EFL A;  1I4T A;  3CAZ A;  3PLT A;  3SYV A;  3Q0K A;  4BNE A;  4H8S A;  3ABH A;  3QNI A;  2ELB A;  2YKT A;  4WPE A;  3DYT A;  2X3V A;  3I2W A;  1I4D A;  2FIC A;  3HAH A;  4AKV A;  1ZWW A;  1I49 A;  2D1L A;  2D4C A;  2RAK A;  2V0O A;  1URU A;  2X3X A;  3Q84 A;  2RAI A;  4NQI A;  4AVM A;  5C5B B;  4DYL A;  2Q13 A;  1X04 A;  2C08 A;  3QE6 A;  1WDZ A;  2EFK A;  4ATM A;  5C5B A;  1I4L A;  3LLL A;  3M3W A;  4DCN C;  4NSW A;  3ACO A;  3QWE A;  2Z0O A;  2Q12 A;  3SOG A; 
#chains in the Genus database with same CATH topology
 1QWU A;  3DPP A;  4JNF A;  3DX1 A;  3ERC C;  1SU7 A;  4BNE A;  4EZX A;  1R33 A;  1GNL A;  2OZN B;  3BUB A;  2FIC A;  2GA9 D;  4AVM A;  4EZU A;  3ACO A;  2YLL A;  2PMR A;  1YWM A;  3Q0K A;  4UDY X;  2YI8 A;  3BUI A;  2F18 A;  4EZR A;  3OWG A;  4IWO A;  4E3C A;  1E1D A;  3BVV A;  3HAI A;  4FZS A;  4JWE A;  3T49 A;  2ELB A;  4JWC A;  3T46 A;  1I4D A;  5FLE X;  3HAH A;  4AKV A;  5KBP A;  1I49 A;  3BVU A;  3A98 A;  3D51 A;  2EX3 B;  1X04 A;  4R5I A;  3VEA A;  3ER9 B;  4IW0 A;  1DKX A;  2GAF D;  4WPC A;  2X3W A;  2ND0 A;  1I4T A;  3OHX M;  4B9Q A;  4EZV A;  3BVX A;  4AZB A;  3EJT A;  2OBM A;  1URU A;  2ALW A;  2N3K A;  3D4Y A;  3DDF A;  3LVT A;  4G6Q A;  2YL5 A;  1R34 A;  3BUD A;  3D52 A;  4JNE A;  1Y2O A;  2RAJ A;  3T4A G;  1SU8 A;  3BVW A;  2GF4 A;  1TQW A;  2D4C A;  5FIG A;  3L3P A;  2Q13 A;  4AZH A;  4EZP A;  3T48 A;  4EZY A;  3RV0 A;  3DPQ A;  2D1L A;  1HTY A;  3DPO A;  1TQU A;  2WIN M;  4IM0 A;  4R5K A;  2EWF A;  1ZWW A;  4IM3 A;  4R5G A;  2F1B A;  4IWP A;  4FM3 A;  1WDZ A;  4R5L A;  3EJQ A;  4JLC A;  3KAV A;  3EJU A;  3HAJ A;  3D2F A;  1TQT A;  3EJR A;  2YIA A;  3DX4 A;  4EZT A;  3QA8 A;  4EZQ A;  2RAI A;  4KIK B;  4AZC B;  2LXY A;  3CV5 A;  1E2U A;  3O3N B;  2Z0O A;  1UPX A;  1QX1 A;  1X03 A;  4HR1 B;  1JQK A;  5E84 A;  4HYB A;  3QNJ A;  3BLB A;  3UIT A;  3EJP A;  2OW7 A;  2F7O A;  4NQI A;  3T47 A;  1SUF A;  1W9M A;  3LLL A;  1U00 A;  3BUP A;  2LM0 A;  4AZC A;  5TKY A;  4JWI A;  4AZ6 A;  2WYH A;  4HR1 A;  2ND1 A;  2ZXQ A;  3D4Z A;  1QWN A;  3KDR A;  1HXK A;  1I4L A;  4EZW A;  4NSW A;  3GI7 A;  2Q12 A;  3DX2 A;  2YLA A;  1TQV A;  4F01 A;  3OK8 A;  2YIV X;  2YI9 A;  2YKT A;  1OA1 A;  3CVR A;  3ZED A;  2OBL A;  5C5B B;  3BVT A;  3F7W A;  3QE6 A;  3C7N A;  2MI7 A;  1GN9 A;  2YL9 A;  3QWE A;  4UDX X;  2QFF A;  4E81 A;  2YL8 A;  3ABH A;  3VKH A;  4M0M A;  1OA0 A;  4AZ7 A;  4HY9 A;  2X3X A;  2F1A A;  3DX3 A;  3LMF A;  3DX0 A;  4NPH A;  3O3O B;  3B53 X;  2YL6 A;  5C5B A;  3B51 X;  2O0I 1;  2QXL A;  2OW6 A;  3I01 A;  1DKZ A;  4JN4 A;  4H6H A;  2Z8Y A;  4AZI A;  1LQ7 A;  1OAO A;  2OO2 A;  2V0O A;  4DYL A;  1TQS A;  2C08 A;  3CKD A;  4EZO A;  2FYV A;  4D8J A;  2F7Q A;  4PO2 A;  2Z0V A;  1ZYL A;  2Z0N A;  3CAZ A;  3I04 A;  3PLT A;  3CZN A;  2X3V A;  3RPM A;  4EZN A;  2RAK A;  3CZS A;  3I39 X;  2NCZ A;  2EFK A;  2WYI A;  1SU6 A;  2KHO A;  4DCN C;  3VEB A;  3SOG A;  4EZZ A;  1GNT A;  4KIK A;  3G9G A;  4I1Q A;  1O7D B;  4H8S A;  3QNI A;  3DYT A;  3O3M B;  3RV1 A;  3B52 X;  1HWW A;  3L3O M;  3M3W A;  1E9V A;  2F7R A;  2F7P A;  3FD9 A;  2JNS A;  2X5C A;  1PS3 A;  2EFL A;  3SYV A;  4FZO A;  4JWD A;  4JL9 A;  3ER8 C;  3I2W A;  4FZP A;  3KAW A;  4AZG A;  4IWQ A;  2PY6 A;  3DDG A;  4AZ5 A;  4EZS A;  3BUQ A;  4R5J A;  4H6I A;  1R5E A;  4IM2 A;  1MJG A;  2QKW A;  2YIB A;  3EJS A;  4WPE A;  3D50 A;  3Q84 A;  2JNK A;  2RT6 A;  1DKY A;  4ATM A;  1O7D C;  3D2E A;  4F00 A; 
#chains in the Genus database with same CATH homology
 3HAI A;  4WPC A;  4FZS A;  3HAJ A;  3OK8 A;  1Y2O A;  2Z0V A;  2RAJ A;  3G9G A;  1X03 A;  2X3W A;  4I1Q A;  2Z0N A;  2EFL A;  1I4T A;  3CAZ A;  3PLT A;  3SYV A;  3Q0K A;  4BNE A;  4H8S A;  3ABH A;  3QNI A;  2ELB A;  2YKT A;  4WPE A;  3DYT A;  2X3V A;  3I2W A;  1I4D A;  2FIC A;  3HAH A;  4AKV A;  1ZWW A;  1I49 A;  2D1L A;  2D4C A;  2RAK A;  2V0O A;  1URU A;  2X3X A;  3Q84 A;  2RAI A;  4NQI A;  4AVM A;  5C5B B;  4DYL A;  2Q13 A;  1X04 A;  2C08 A;  3QE6 A;  1WDZ A;  2EFK A;  4ATM A;  5C5B A;  1I4L A;  3LLL A;  3M3W A;  4DCN C;  4NSW A;  3ACO A;  3QWE A;  2Z0O A;  2Q12 A;  3SOG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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