3M3WA

Crystal strcuture of mouse pacsin3 bar domain mutant
Total Genus 112
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
288
structure length
280
Chain Sequence
GSFWEAGNYRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLADWARKWRGAVEKGPQYGTLEKAWHAFFTAAERLSELHLEVREKLHGPDSERVRTWQRGAFHGFRASRAAEDGFRKAQKPWLKRLKEVEASKKSYHTARKDEKTAQTRESHAKADSSMQLRKLQERVGRCTKEAEKMKTQYEQTLAELNRYTPRYMEDMEQAFESCQAAERQRLLFFKDVLLTLHQHLDLSSSDKFHELHRDLQQSIEAASDEEDLRWWRSTHGPGMAMNWPQFEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Rigidity of wedge loop in PACSIN 3 protein is a key factor in dictating diameters of tubules
pubmed doi rcsb
molecule tags Endocytosis
source organism Mus musculus
molecule keywords Protein kinase C and casein kinase II substrate protein 3
total genus 112
structure length 280
sequence length 288
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-03-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3m3wA01
1URUA 2Q13A 4NSWA 3I2WA 3SYVA 3SOGA 2Z0NA 3ABHA 4WPCA 2C08A 2YKTA 1Y2OA 1I49A 1I4LA 2Q12A 2D1LA 2FICA 1X04A 2EFLA 4ATMA 2Z0VA 4I1QA 3G9GA 4H8SA 3Q0KA 3HAJA 2V0OA 3QNIA 3LLLA 4NQIA 3ACOA 5C5BB 3DYTA 1I4DA 4DYLA 3HAHA 4AKVA 1I4TA 2RAKA 4BNEA 5C5BA 2X3WA 2RAIA 3HAIA 2D4CA 2X3VA 3PLTA 3Q84A 1X03A 4WPEA 3CAZA 3QE6A 2RAJA 4FZSA 3QWEA 3M3WA 1WDZA 2Z0OA 3OK8A 1ZWWA 2X3XA 2EFKA 4AVMA 2ELBA 4DCNC
chains in the Genus database with same CATH superfamily
3B53X 4IWQA 3BVTA 1UPXA 1I49A 3CKDA 4DYLA 2RAIA 3O3NB 2YL8A 1X03A 3CAZA 3CZNA 2KHOA 4FZPA 4IWPA 1R34A 5E84A 1ZYLA 4H6IA 3BUQA 3D50A 3LVTA 3I04A 2YL9A 1SUFA 2ND1A 5TKYA 2F7RA 3BLBA 2OW6A 4WPEA 4JWIA 2OZNB 1W9MA 4IM0A 3DDGA 3T48A 1U00A 4AZCA 2GA9D 4JL9A 3FD9A 2Z8YA 4EZSA 4D8JA 3T4AG 4KIKA 2YLAA 3EJSA 2F7QA 1R5EA 4JWEA 3QE6A 2WYIA 3B52X 3BUIA 4UDXX 1TQWA 3D51A 2ELBA 3DX3A 3EJRA 2Q13A 4NSWA 2FYVA 1I4LA 2Q12A 1GNTA 1O7DB 3GI7A 1LQ7A 2YIVX 1R33A 2X3VA 3ERCC 3DPPA 2NCZA 3VEBA 3I2WA 3CVRA 2N3KA 4IW0A 4EZPA 4F00A 3ACOA 3EJPA 5C5BB 2RAKA 4BNEA 3RPMA 1QX1A 4EZZA 1QWUA 2GF4A 2OBMA 4EZYA 1DKYA 4M0MA 4AZBA 2F18A 1URUA 4IWOA 3BVVA 3ABHA 2F7OA 4I1QA 2X5CA 3QNIA 1HWWA 2ND0A 4R5LA 4EZTA 3ER9B 1HXKA 2LM0A 1GN9A 4NPHA 4JNFA 2WYHA 3QNJA 4EZVA 4IM2A 3RV0A 2O0I1 2RT6A 2PY6A 2YI8A 4H8SA 2QXLA 4AKVA 1E1DA 4AZ7A 1SU6A 2EX3B 4UDYX 4AZ6A 3D4YA 4HR1A 3ER8C 3VEAA 3SYVA 4EZWA 5FIGA 1X04A 2EWFA 1SU8A 3ZEDA 3C7NA 3DYTA 2F1AA 3D2FA 3L3OM 2MI7A 3OWGA 1E9VA 1O7DC 1OAOA 4B9QA 3Q84A 1GNLA 4JLCA 4EZXA 4IM3A 3QWEA 2EFKA 3OHXM 3EJTA 3CZSA 3L3PA 2FICA 3DPQA 3DX1A 5C5BA 2OO2A 4JWCA 3O3OB 3BUBA 4PO2A 2GAFD 4JNEA 2X3XA 4DCNC 4JWDA 2YI9A 3F7WA 4EZNA 4KIKB 2YIAA 2JNSA 3LMFA 3I01A 2WINM 4HYBA 4EZUA 3HAIA 2D4CA 2OW7A 2RAJA 1E2UA 3A98A 2C08A 1Y2OA 1HTYA 2LXYA 3G9GA 3Q0KA 2V0OA 1I4DA 3BVXA 3PLTA 3T46A 4JN4A 1TQSA 3KAVA 2PMRA 3M3WA 3KDRA 3BUPA 1PS3A 3DX0A 3KAWA 3EJUA 4R5IA 4FZOA 4WPCA 4AZGA 2YKTA 3I39X 2F7PA 3CV5A 1I4TA 1DKZA 3T47A 3VKHA 3EJQA 1OA1A 3DX2A 3T49A 4HY9A 4FM3A 2QKWA 2Z0NA 1TQTA 3DPOA 1YWMA 3D52A 4NQIA 1TQVA 4AZIA 3BUDA 2X3WA 3RV1A 3DX4A 4EZRA 4H6HA 2JNKA 1QWNA 3D2EA 1ZWWA 4AVMA 2ALWA 2YLLA 3DDFA 3B51X 1JQKA 4ATMA 2YL6A 4R5KA 4AZ5A 1OA0A 1DKXA 1TQUA 4HR1B 4FZSA 1WDZA 2Z0OA 2ZXQA 4AZCB 4E81A 4R5GA 2QFFA 4E3CA 4EZOA 2D1LA 2EFLA 2Z0VA 3BVWA 3UITA 3HAJA 4R5JA 3LLLA 3HAHA 4AZHA 3D4ZA 4EZQA 2F1BA 1MJGA 5FLEX 3SOGA 1SU7A 5KBPA 3BVUA 2YIBA 4G6QA 2YL5A 2OBLA 4F01A 3O3MB 3OK8A 3QA8A
chains in the Genus database with same CATH topology
1URUA 2Q13A 4NSWA 3I2WA 3SYVA 3SOGA 2Z0NA 3ABHA 4WPCA 2C08A 2YKTA 1Y2OA 1I49A 1I4LA 2Q12A 2D1LA 2FICA 1X04A 2EFLA 4ATMA 2Z0VA 4I1QA 3G9GA 4H8SA 3Q0KA 3HAJA 2V0OA 3QNIA 3LLLA 4NQIA 3ACOA 5C5BB 3DYTA 1I4DA 4DYLA 3HAHA 4AKVA 1I4TA 2RAKA 4BNEA 5C5BA 2X3WA 2RAIA 3HAIA 2D4CA 2X3VA 3PLTA 3Q84A 1X03A 4WPEA 3CAZA 3QE6A 2RAJA 4FZSA 3QWEA 3M3WA 1WDZA 2Z0OA 3OK8A 1ZWWA 2X3XA 2EFKA 4AVMA 2ELBA 4DCNC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1URU A;  2Q13 A;  4NSW A;  3I2W A;  3SYV A;  3SOG A;  2Z0N A;  3ABH A;  4WPC A;  2C08 A;  2YKT A;  1Y2O A;  1I49 A;  1I4L A;  2Q12 A;  2D1L A;  2FIC A;  1X04 A;  2EFL A;  4ATM A;  2Z0V A;  4I1Q A;  3G9G A;  4H8S A;  3Q0K A;  3HAJ A;  2V0O A;  3QNI A;  3LLL A;  4NQI A;  3ACO A;  5C5B B;  3DYT A;  1I4D A;  4DYL A;  3HAH A;  4AKV A;  1I4T A;  2RAK A;  4BNE A;  5C5B A;  2X3W A;  2RAI A;  3HAI A;  2D4C A;  2X3V A;  3PLT A;  3Q84 A;  1X03 A;  4WPE A;  3CAZ A;  3QE6 A;  2RAJ A;  4FZS A;  3QWE A;  3M3W A;  1WDZ A;  2Z0O A;  3OK8 A;  1ZWW A;  2X3X A;  2EFK A;  4AVM A;  2ELB A;  4DCN C; 
#chains in the Genus database with same CATH topology
 3B53 X;  4IWQ A;  3BVT A;  1UPX A;  1I49 A;  3CKD A;  4DYL A;  2RAI A;  3O3N B;  2YL8 A;  1X03 A;  3CAZ A;  3CZN A;  2KHO A;  4FZP A;  4IWP A;  1R34 A;  5E84 A;  1ZYL A;  4H6I A;  3BUQ A;  3D50 A;  3LVT A;  3I04 A;  2YL9 A;  1SUF A;  2ND1 A;  5TKY A;  2F7R A;  3BLB A;  2OW6 A;  4WPE A;  4JWI A;  2OZN B;  1W9M A;  4IM0 A;  3DDG A;  3T48 A;  1U00 A;  4AZC A;  2GA9 D;  4JL9 A;  3FD9 A;  2Z8Y A;  4EZS A;  4D8J A;  3T4A G;  4KIK A;  2YLA A;  3EJS A;  2F7Q A;  1R5E A;  4JWE A;  3QE6 A;  2WYI A;  3B52 X;  3BUI A;  4UDX X;  1TQW A;  3D51 A;  2ELB A;  3DX3 A;  3EJR A;  2Q13 A;  4NSW A;  2FYV A;  1I4L A;  2Q12 A;  1GNT A;  1O7D B;  3GI7 A;  1LQ7 A;  2YIV X;  1R33 A;  2X3V A;  3ERC C;  3DPP A;  2NCZ A;  3VEB A;  3I2W A;  3CVR A;  2N3K A;  4IW0 A;  4EZP A;  4F00 A;  3ACO A;  3EJP A;  5C5B B;  2RAK A;  4BNE A;  3RPM A;  1QX1 A;  4EZZ A;  1QWU A;  2GF4 A;  2OBM A;  4EZY A;  1DKY A;  4M0M A;  4AZB A;  2F18 A;  1URU A;  4IWO A;  3BVV A;  3ABH A;  2F7O A;  4I1Q A;  2X5C A;  3QNI A;  1HWW A;  2ND0 A;  4R5L A;  4EZT A;  3ER9 B;  1HXK A;  2LM0 A;  1GN9 A;  4NPH A;  4JNF A;  2WYH A;  3QNJ A;  4EZV A;  4IM2 A;  3RV0 A;  2O0I 1;  2RT6 A;  2PY6 A;  2YI8 A;  4H8S A;  2QXL A;  4AKV A;  1E1D A;  4AZ7 A;  1SU6 A;  2EX3 B;  4UDY X;  4AZ6 A;  3D4Y A;  4HR1 A;  3ER8 C;  3VEA A;  3SYV A;  4EZW A;  5FIG A;  1X04 A;  2EWF A;  1SU8 A;  3ZED A;  3C7N A;  3DYT A;  2F1A A;  3D2F A;  3L3O M;  2MI7 A;  3OWG A;  1E9V A;  1O7D C;  1OAO A;  4B9Q A;  3Q84 A;  1GNL A;  4JLC A;  4EZX A;  4IM3 A;  3QWE A;  2EFK A;  3OHX M;  3EJT A;  3CZS A;  3L3P A;  2FIC A;  3DPQ A;  3DX1 A;  5C5B A;  2OO2 A;  4JWC A;  3O3O B;  3BUB A;  4PO2 A;  2GAF D;  4JNE A;  2X3X A;  4DCN C;  4JWD A;  2YI9 A;  3F7W A;  4EZN A;  4KIK B;  2YIA A;  2JNS A;  3LMF A;  3I01 A;  2WIN M;  4HYB A;  4EZU A;  3HAI A;  2D4C A;  2OW7 A;  2RAJ A;  1E2U A;  3A98 A;  2C08 A;  1Y2O A;  1HTY A;  2LXY A;  3G9G A;  3Q0K A;  2V0O A;  1I4D A;  3BVX A;  3PLT A;  3T46 A;  4JN4 A;  1TQS A;  3KAV A;  2PMR A;  3M3W A;  3KDR A;  3BUP A;  1PS3 A;  3DX0 A;  3KAW A;  3EJU A;  4R5I A;  4FZO A;  4WPC A;  4AZG A;  2YKT A;  3I39 X;  2F7P A;  3CV5 A;  1I4T A;  1DKZ A;  3T47 A;  3VKH A;  3EJQ A;  1OA1 A;  3DX2 A;  3T49 A;  4HY9 A;  4FM3 A;  2QKW A;  2Z0N A;  1TQT A;  3DPO A;  1YWM A;  3D52 A;  4NQI A;  1TQV A;  4AZI A;  3BUD A;  2X3W A;  3RV1 A;  3DX4 A;  4EZR A;  4H6H A;  2JNK A;  1QWN A;  3D2E A;  1ZWW A;  4AVM A;  2ALW A;  2YLL A;  3DDF A;  3B51 X;  1JQK A;  4ATM A;  2YL6 A;  4R5K A;  4AZ5 A;  1OA0 A;  1DKX A;  1TQU A;  4HR1 B;  4FZS A;  1WDZ A;  2Z0O A;  2ZXQ A;  4AZC B;  4E81 A;  4R5G A;  2QFF A;  4E3C A;  4EZO A;  2D1L A;  2EFL A;  2Z0V A;  3BVW A;  3UIT A;  3HAJ A;  4R5J A;  3LLL A;  3HAH A;  4AZH A;  3D4Z A;  4EZQ A;  2F1B A;  1MJG A;  5FLE X;  3SOG A;  1SU7 A;  5KBP A;  3BVU A;  2YIB A;  4G6Q A;  2YL5 A;  2OBL A;  4F01 A;  3O3M B;  3OK8 A;  3QA8 A; 
#chains in the Genus database with same CATH homology
 1URU A;  2Q13 A;  4NSW A;  3I2W A;  3SYV A;  3SOG A;  2Z0N A;  3ABH A;  4WPC A;  2C08 A;  2YKT A;  1Y2O A;  1I49 A;  1I4L A;  2Q12 A;  2D1L A;  2FIC A;  1X04 A;  2EFL A;  4ATM A;  2Z0V A;  4I1Q A;  3G9G A;  4H8S A;  3Q0K A;  3HAJ A;  2V0O A;  3QNI A;  3LLL A;  4NQI A;  3ACO A;  5C5B B;  3DYT A;  1I4D A;  4DYL A;  3HAH A;  4AKV A;  1I4T A;  2RAK A;  4BNE A;  5C5B A;  2X3W A;  2RAI A;  3HAI A;  2D4C A;  2X3V A;  3PLT A;  3Q84 A;  1X03 A;  4WPE A;  3CAZ A;  3QE6 A;  2RAJ A;  4FZS A;  3QWE A;  3M3W A;  1WDZ A;  2Z0O A;  3OK8 A;  1ZWW A;  2X3X A;  2EFK A;  4AVM A;  2ELB A;  4DCN C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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