3Q0KA

Crystal structure of human pacsin 2 f-bar
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
289
structure length
287
Chain Sequence
DSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKAPSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQEEW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of human PACSIN 2 F-BAR domain
rcsb
molecule tags Endocytosis
source organism Homo sapiens
molecule keywords Protein kinase C and casein kinase substrate in neurons prot
total genus 113
structure length 287
sequence length 289
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2010-12-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3q0kA01
2ELBA 4NQIA 3HAHA 3QWEA 5C5BB 1WDZA 1ZWWA 4ATMA 3HAIA 2X3VA 1I4TA 3OK8A 2EFKA 1X04A 2D1LA 3SYVA 3SOGA 3PLTA 5C5BA 2RAIA 1URUA 4I1QA 4DYLA 2Q13A 1Y2OA 3HAJA 3Q0KA 3Q84A 2X3XA 4AKVA 2FICA 2Q12A 2D4CA 2Z0NA 1I4LA 4DCNC 2C08A 2X3WA 3ACOA 4AVMA 2Z0VA 4H8SA 3DYTA 2V0OA 4WPCA 2Z0OA 3CAZA 4NSWA 2RAJA 3LLLA 3QNIA 4WPEA 4BNEA 4FZSA 3ABHA 2YKTA 2EFLA 1I4DA 3G9GA 3QE6A 3I2WA 3M3WA 1X03A 1I49A 2RAKA
chains in the Genus database with same CATH superfamily
3DX0A 2EWFA 3EJTA 4EZPA 3HAIA 2D1LA 2F1BA 4AZ7A 2OBLA 2X3XA 2RT6A 4UDYX 1SU7A 1QWNA 3QNIA 4JN4A 3T4AG 4EZOA 3CV5A 1ZWWA 3B53X 3BLBA 2ND1A 3O3NB 3DPPA 1MJGA 4F00A 1I4DA 3A98A 1TQTA 1WDZA 3DX3A 4AZGA 4ATMA 1JQKA 4JWDA 5C5BA 2JNKA 3FD9A 1Y2OA 4EZNA 2FICA 2Q12A 2YIBA 3OHXM 4H8SA 1ZYLA 3ER8C 1TQWA 2OW7A 3RPMA 3T47A 3D2EA 2FYVA 2PMRA 1YWMA 2OO2A 5KBPA 4BNEA 3BVWA 1QWUA 2OW6A 1GNLA 2GAFD 3EJQA 3BUBA 4R5LA 2C08A 1R5EA 3CZSA 3KAWA 2F1AA 4WPCA 3T48A 4JL9A 3RV0A 2YL5A 3M3WA 4HR1B 4EZWA 2WYHA 1X04A 2RAIA 4I1QA 4AKVA 4AVMA 3EJPA 2V0OA 2YL8A 3BVVA 3D4ZA 3D51A 2MI7A 1HTYA 4KIKA 3I2WA 2YIAA 3DYTA 2F7QA 1I4TA 3OK8A 3QNJA 1E1DA 4R5KA 3SOGA 3F7WA 2Q13A 3O3OB 3I04A 3EJSA 2NCZA 4IWQA 1TQSA 2EX3B 2OZNB 3KAVA 1TQVA 3G9GA 4R5GA 4F01A 2OBMA 4NQIA 3DDGA 2N3KA 1SU6A 3BUDA 3RV1A 2LXYA 4IM0A 1GN9A 4EZYA 3D52A 3VKHA 2WYIA 3GI7A 4AZBA 2F7OA 2YI9A 3BUPA 4AZCA 3QE6A 1U00A 5C5BB 3KDRA 4JWIA 4AZCB 2D4CA 4M0MA 4R5IA 3LLLA 3B52X 4FZSA 3ABHA 1OAOA 5FLEX 3CKDA 3BVUA 2F18A 3CVRA 1R34A 4EZRA 2O0I1 3UITA 5E84A 1PS3A 4JNFA 3T46A 2YL6A 2Z0NA 4EZUA 4H6HA 4FZPA 3ZEDA 1O7DC 2GA9D 4E81A 3QWEA 3BUQA 2F7PA 3DPOA 4IWOA 4EZXA 5FIGA 4B9QA 3DX4A 4DYLA 3Q84A 3VEAA 4HYBA 4JLCA 4AZ6A 1W9MA 4EZZA 1E9VA 1R33A 3C7NA 1E2UA 2F7RA 4UDXX 1I49A 3HAHA 4IWPA 1O7DB 1DKYA 3PLTA 1URUA 2YL9A 1OA1A 2Z8YA 3Q0KA 1I4LA 3ACOA 4KIKB 4FZOA 2RAJA 4WPEA 2JNSA 4EZTA 4E3CA 2Z0VA 2RAKA 1LQ7A 4IW0A 4NPHA 3BVXA 2EFKA 3B51X 1QX1A 3ER9B 2YI8A 4AZHA 2X3WA 3LMFA 3L3PA 2Z0OA 4D8JA 1OA0A 4IM2A 3EJUA 2YIVX 2KHOA 4EZQA 4AZIA 2WINM 3LVTA 2ND0A 2LM0A 3VEBA 3DPQA 3L3OM 3HAJA 1GNTA 3EJRA 3BVTA 4HY9A 3I39X 4PO2A 5TKYA 3ERCC 3QA8A 3O3MB 2YKTA 2QFFA 2X5CA 4H6IA 2PY6A 3DX1A 3SYVA 1HXKA 1DKXA 1TQUA 1DKZA 4IM3A 2QKWA 4EZSA 1SU8A 3CAZA 4NSWA 2YLAA 2EFLA 2ZXQA 1SUFA 4EZVA 3BUIA 2GF4A 1X03A 3D2FA 2ALWA 3I01A 2ELBA 4JWCA 4JWEA 2QXLA 2X3VA 3DDFA 4HR1A 4JNEA 4R5JA 4DCNC 3CZNA 4AZ5A 3T49A 3OWGA 4G6QA 4FM3A 2YLLA 1UPXA 3D4YA 3DX2A 3D50A 1HWWA
chains in the Genus database with same CATH topology
2ELBA 4NQIA 3HAHA 3QWEA 5C5BB 1WDZA 1ZWWA 4ATMA 3HAIA 2X3VA 1I4TA 3OK8A 2EFKA 1X04A 2D1LA 3SYVA 3SOGA 3PLTA 5C5BA 2RAIA 1URUA 4I1QA 4DYLA 2Q13A 1Y2OA 3HAJA 3Q0KA 3Q84A 2X3XA 4AKVA 2FICA 2Q12A 2D4CA 2Z0NA 1I4LA 4DCNC 2C08A 2X3WA 3ACOA 4AVMA 2Z0VA 4H8SA 3DYTA 2V0OA 4WPCA 2Z0OA 3CAZA 4NSWA 2RAJA 3LLLA 3QNIA 4WPEA 4BNEA 4FZSA 3ABHA 2YKTA 2EFLA 1I4DA 3G9GA 3QE6A 3I2WA 3M3WA 1X03A 1I49A 2RAKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ELB A;  4NQI A;  3HAH A;  3QWE A;  5C5B B;  1WDZ A;  1ZWW A;  4ATM A;  3HAI A;  2X3V A;  1I4T A;  3OK8 A;  2EFK A;  1X04 A;  2D1L A;  3SYV A;  3SOG A;  3PLT A;  5C5B A;  2RAI A;  1URU A;  4I1Q A;  4DYL A;  2Q13 A;  1Y2O A;  3HAJ A;  3Q0K A;  3Q84 A;  2X3X A;  4AKV A;  2FIC A;  2Q12 A;  2D4C A;  2Z0N A;  1I4L A;  4DCN C;  2C08 A;  2X3W A;  3ACO A;  4AVM A;  2Z0V A;  4H8S A;  3DYT A;  2V0O A;  4WPC A;  2Z0O A;  3CAZ A;  4NSW A;  2RAJ A;  3LLL A;  3QNI A;  4WPE A;  4BNE A;  4FZS A;  3ABH A;  2YKT A;  2EFL A;  1I4D A;  3G9G A;  3QE6 A;  3I2W A;  3M3W A;  1X03 A;  1I49 A;  2RAK A; 
#chains in the Genus database with same CATH topology
 3DX0 A;  2EWF A;  3EJT A;  4EZP A;  3HAI A;  2D1L A;  2F1B A;  4AZ7 A;  2OBL A;  2X3X A;  2RT6 A;  4UDY X;  1SU7 A;  1QWN A;  3QNI A;  4JN4 A;  3T4A G;  4EZO A;  3CV5 A;  1ZWW A;  3B53 X;  3BLB A;  2ND1 A;  3O3N B;  3DPP A;  1MJG A;  4F00 A;  1I4D A;  3A98 A;  1TQT A;  1WDZ A;  3DX3 A;  4AZG A;  4ATM A;  1JQK A;  4JWD A;  5C5B A;  2JNK A;  3FD9 A;  1Y2O A;  4EZN A;  2FIC A;  2Q12 A;  2YIB A;  3OHX M;  4H8S A;  1ZYL A;  3ER8 C;  1TQW A;  2OW7 A;  3RPM A;  3T47 A;  3D2E A;  2FYV A;  2PMR A;  1YWM A;  2OO2 A;  5KBP A;  4BNE A;  3BVW A;  1QWU A;  2OW6 A;  1GNL A;  2GAF D;  3EJQ A;  3BUB A;  4R5L A;  2C08 A;  1R5E A;  3CZS A;  3KAW A;  2F1A A;  4WPC A;  3T48 A;  4JL9 A;  3RV0 A;  2YL5 A;  3M3W A;  4HR1 B;  4EZW A;  2WYH A;  1X04 A;  2RAI A;  4I1Q A;  4AKV A;  4AVM A;  3EJP A;  2V0O A;  2YL8 A;  3BVV A;  3D4Z A;  3D51 A;  2MI7 A;  1HTY A;  4KIK A;  3I2W A;  2YIA A;  3DYT A;  2F7Q A;  1I4T A;  3OK8 A;  3QNJ A;  1E1D A;  4R5K A;  3SOG A;  3F7W A;  2Q13 A;  3O3O B;  3I04 A;  3EJS A;  2NCZ A;  4IWQ A;  1TQS A;  2EX3 B;  2OZN B;  3KAV A;  1TQV A;  3G9G A;  4R5G A;  4F01 A;  2OBM A;  4NQI A;  3DDG A;  2N3K A;  1SU6 A;  3BUD A;  3RV1 A;  2LXY A;  4IM0 A;  1GN9 A;  4EZY A;  3D52 A;  3VKH A;  2WYI A;  3GI7 A;  4AZB A;  2F7O A;  2YI9 A;  3BUP A;  4AZC A;  3QE6 A;  1U00 A;  5C5B B;  3KDR A;  4JWI A;  4AZC B;  2D4C A;  4M0M A;  4R5I A;  3LLL A;  3B52 X;  4FZS A;  3ABH A;  1OAO A;  5FLE X;  3CKD A;  3BVU A;  2F18 A;  3CVR A;  1R34 A;  4EZR A;  2O0I 1;  3UIT A;  5E84 A;  1PS3 A;  4JNF A;  3T46 A;  2YL6 A;  2Z0N A;  4EZU A;  4H6H A;  4FZP A;  3ZED A;  1O7D C;  2GA9 D;  4E81 A;  3QWE A;  3BUQ A;  2F7P A;  3DPO A;  4IWO A;  4EZX A;  5FIG A;  4B9Q A;  3DX4 A;  4DYL A;  3Q84 A;  3VEA A;  4HYB A;  4JLC A;  4AZ6 A;  1W9M A;  4EZZ A;  1E9V A;  1R33 A;  3C7N A;  1E2U A;  2F7R A;  4UDX X;  1I49 A;  3HAH A;  4IWP A;  1O7D B;  1DKY A;  3PLT A;  1URU A;  2YL9 A;  1OA1 A;  2Z8Y A;  3Q0K A;  1I4L A;  3ACO A;  4KIK B;  4FZO A;  2RAJ A;  4WPE A;  2JNS A;  4EZT A;  4E3C A;  2Z0V A;  2RAK A;  1LQ7 A;  4IW0 A;  4NPH A;  3BVX A;  2EFK A;  3B51 X;  1QX1 A;  3ER9 B;  2YI8 A;  4AZH A;  2X3W A;  3LMF A;  3L3P A;  2Z0O A;  4D8J A;  1OA0 A;  4IM2 A;  3EJU A;  2YIV X;  2KHO A;  4EZQ A;  4AZI A;  2WIN M;  3LVT A;  2ND0 A;  2LM0 A;  3VEB A;  3DPQ A;  3L3O M;  3HAJ A;  1GNT A;  3EJR A;  3BVT A;  4HY9 A;  3I39 X;  4PO2 A;  5TKY A;  3ERC C;  3QA8 A;  3O3M B;  2YKT A;  2QFF A;  2X5C A;  4H6I A;  2PY6 A;  3DX1 A;  3SYV A;  1HXK A;  1DKX A;  1TQU A;  1DKZ A;  4IM3 A;  2QKW A;  4EZS A;  1SU8 A;  3CAZ A;  4NSW A;  2YLA A;  2EFL A;  2ZXQ A;  1SUF A;  4EZV A;  3BUI A;  2GF4 A;  1X03 A;  3D2F A;  2ALW A;  3I01 A;  2ELB A;  4JWC A;  4JWE A;  2QXL A;  2X3V A;  3DDF A;  4HR1 A;  4JNE A;  4R5J A;  4DCN C;  3CZN A;  4AZ5 A;  3T49 A;  3OWG A;  4G6Q A;  4FM3 A;  2YLL A;  1UPX A;  3D4Y A;  3DX2 A;  3D50 A;  1HWW A; 
#chains in the Genus database with same CATH homology
 2ELB A;  4NQI A;  3HAH A;  3QWE A;  5C5B B;  1WDZ A;  1ZWW A;  4ATM A;  3HAI A;  2X3V A;  1I4T A;  3OK8 A;  2EFK A;  1X04 A;  2D1L A;  3SYV A;  3SOG A;  3PLT A;  5C5B A;  2RAI A;  1URU A;  4I1Q A;  4DYL A;  2Q13 A;  1Y2O A;  3HAJ A;  3Q0K A;  3Q84 A;  2X3X A;  4AKV A;  2FIC A;  2Q12 A;  2D4C A;  2Z0N A;  1I4L A;  4DCN C;  2C08 A;  2X3W A;  3ACO A;  4AVM A;  2Z0V A;  4H8S A;  3DYT A;  2V0O A;  4WPC A;  2Z0O A;  3CAZ A;  4NSW A;  2RAJ A;  3LLL A;  3QNI A;  4WPE A;  4BNE A;  4FZS A;  3ABH A;  2YKT A;  2EFL A;  1I4D A;  3G9G A;  3QE6 A;  3I2W A;  3M3W A;  1X03 A;  1I49 A;  2RAK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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