3Q84A

Crystal structure of human pacsin 1 f-bar domain
Total Genus 112
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
293
structure length
285
Chain Sequence
TDSFWEVGNYKRTVKRIDDGHRLCNDLMNCVQERAKIEKAYGQQLTDWAKRWRQLIEKGPQYGSLERAWGAIMTEADKVSELHQEVKNNLLNEDLEKVKNWQKDAYHKQIMGGFKETKEAEDGFRKAQKPWAKKMKELEAAKKAYHLACKEEKLAMTREMTEVPQKKLQDKVDKCKQDVQKTQEKYEKVLEDVGKTTPQYMENMEQVFEQCQQFEEKRLVFLKEVLLDIKRHLNLAENSSYIHVYRELEQAIRGADAQEDLRWFRSTSGPGMPMNWPQFEEWNPD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of human PACSIN 1 F-BAR domain
rcsb
molecule tags Endocytosis
molecule keywords Protein kinase C and casein kinase substrate in neurons prot
total genus 112
structure length 285
sequence length 293
chains with identical sequence B, G, H, M, N
ec nomenclature
pdb deposition date 2011-01-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3q84A01
1I4LA 2Z0OA 4BNEA 2RAIA 3OK8A 3HAIA 4H8SA 4NQIA 4ATMA 4DYLA 1Y2OA 1URUA 2RAJA 3QWEA 2X3VA 2V0OA 3DYTA 3PLTA 2C08A 2RAKA 4I1QA 1WDZA 4WPEA 2X3XA 3ABHA 4NSWA 2X3WA 1I4TA 2YKTA 2D4CA 2EFLA 5C5BB 1X03A 3Q0KA 3SOGA 3SYVA 3ACOA 4DCNC 2Z0NA 3QE6A 1I49A 3Q84A 2FICA 3HAJA 3LLLA 2Q12A 4AVMA 3G9GA 4WPCA 4AKVA 2Q13A 4FZSA 3M3WA 2EFKA 1I4DA 3I2WA 3CAZA 5C5BA 2ELBA 1X04A 2Z0VA 3QNIA 1ZWWA 3HAHA 2D1LA
chains in the Genus database with same CATH superfamily
1O7DB 4IM0A 4E81A 2GA9D 1URUA 2RAJA 2X3VA 4G6QA 3ABHA 5KBPA 4F01A 1QX1A 3Q0KA 4AZCA 3QE6A 1PS3A 4HY9A 1MJGA 4WPCA 2Z8YA 3DX3A 4EZQA 1YWMA 4B9QA 3CV5A 2OO2A 4AZ5A 2F7PA 2Q12A 4EZRA 2YIAA 2OW7A 3RPMA 3ER9B 4R5LA 4WPEA 1TQUA 2GAFD 2D4CA 2ND1A 3DX4A 4JN4A 3T46A 3DPQA 2O0I1 3A98A 4DCNC 2ND0A 3OHXM 4NPHA 4AZHA 3Q84A 4EZOA 4EZYA 4FZSA 2YL5A 1ZWWA 3HAHA 2EWFA 2MI7A 3HAIA 3RV0A 3L3OM 2PY6A 3T49A 4AZBA 3KAVA 2ZXQA 1SU7A 4EZPA 3BVUA 2ELBA 1X04A 4UDXX 3CZNA 4H8SA 2QFFA 4KIKA 4UDYX 1W9MA 4R5KA 2YI9A 2X3WA 3D4YA 2PMRA 3T47A 4AKVA 3D4ZA 5FIGA 4JWEA 2QXLA 2GF4A 3SOGA 1SUFA 4H6HA 4NQIA 4ATMA 1TQTA 2YKTA 4EZVA 1GNTA 1TQVA 2OW6A 3EJQA 3ACOA 1QWUA 4EZXA 3CZSA 1GNLA 1E1DA 4D8JA 2NCZA 2EX3B 3O3NB 5FLEX 3DX2A 2YI8A 1JQKA 2RAIA 3RV1A 3VEAA 3DDFA 4HR1B 1ZYLA 4R5JA 4AZIA 2F1BA 2FICA 3LLLA 1E2UA 4R5GA 3PLTA 2V0OA 3L3PA 1R5EA 3VKHA 3QWEA 3D51A 5TKYA 3VEBA 3LVTA 5C5BB 1X03A 3SYVA 3KAWA 2F1AA 3EJUA 4AVMA 2YIVX 3M3WA 3EJTA 2Z0VA 3QNIA 2D1LA 4FZOA 1I4LA 4EZNA 2YL8A 3DX0A 4AZ7A 2WYHA 3BUBA 4JWCA 1I4TA 3I39X 1HWWA 3BUPA 2Z0NA 3BUQA 3UITA 4AZ6A 2Q13A 1O7DC 2YL9A 1U00A 4R5IA 3O3MB 3DYTA 1TQWA 2RAKA 3BVVA 1HTYA 3ER8C 1OA1A 2OBLA 3QNJA 2WINM 4HYBA 3B51X 3BUIA 3CAZA 3KDRA 1LQ7A 2Z0OA 2YLAA 1SU8A 1Y2OA 2RT6A 1QWNA 3EJSA 3D52A 3BVWA 4EZZA 3BLBA 1R34A 2KHOA 3DDGA 3D50A 3EJRA 3I2WA 2YL6A 3DPPA 2JNKA 4BNEA 2JNSA 4E3CA 2N3KA 4JWDA 1WDZA 2X3XA 1GN9A 4F00A 1HXKA 1UPXA 2YLLA 1SU6A 3GI7A 4IM3A 4FZPA 3D2FA 1I49A 3HAJA 3G9GA 2WYIA 4KIKB 4IWQA 2EFKA 4IWPA 3EJPA 3ERCC 4JNFA 3B52X 3DPOA 4JNEA 4AZGA 3DX1A 4NSWA 2OBMA 4PO2A 3OWGA 3BUDA 1E9VA 4IM2A 3D2EA 3T48A 4EZWA 4JL9A 4AZCB 2LXYA 3FD9A 4FM3A 1OAOA 4JLCA 2X5CA 2F7QA 1DKYA 2YIBA 1I4DA 4H6IA 2OZNB 4M0MA 3C7NA 4IWOA 2QKWA 1OA0A 3OK8A 4EZTA 1DKXA 4I1QA 2C08A 2FYVA 3LMFA 2EFLA 1DKZA 3CKDA 1TQSA 3T4AG 4HR1A 4IW0A 3BVXA 5E84A 2F7RA 3ZEDA 3CVRA 3F7WA 2F18A 2LM0A 3B53X 4DYLA 3I04A 4JWIA 3O3OB 4EZUA 2ALWA 4EZSA 3I01A 3QA8A 3BVTA 2F7OA 5C5BA 1R33A
chains in the Genus database with same CATH topology
1I4LA 2Z0OA 4BNEA 2RAIA 3OK8A 3HAIA 4H8SA 4NQIA 4ATMA 4DYLA 1Y2OA 1URUA 2RAJA 3QWEA 2X3VA 2V0OA 3DYTA 3PLTA 2C08A 2RAKA 4I1QA 1WDZA 4WPEA 2X3XA 3ABHA 4NSWA 2X3WA 1I4TA 2YKTA 2D4CA 2EFLA 5C5BB 1X03A 3Q0KA 3SOGA 3SYVA 3ACOA 4DCNC 2Z0NA 3QE6A 1I49A 3Q84A 2FICA 3HAJA 3LLLA 2Q12A 4AVMA 3G9GA 4WPCA 4AKVA 2Q13A 4FZSA 3M3WA 2EFKA 1I4DA 3I2WA 3CAZA 5C5BA 2ELBA 1X04A 2Z0VA 3QNIA 1ZWWA 3HAHA 2D1LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I4L A;  2Z0O A;  4BNE A;  2RAI A;  3OK8 A;  3HAI A;  4H8S A;  4NQI A;  4ATM A;  4DYL A;  1Y2O A;  1URU A;  2RAJ A;  3QWE A;  2X3V A;  2V0O A;  3DYT A;  3PLT A;  2C08 A;  2RAK A;  4I1Q A;  1WDZ A;  4WPE A;  2X3X A;  3ABH A;  4NSW A;  2X3W A;  1I4T A;  2YKT A;  2D4C A;  2EFL A;  5C5B B;  1X03 A;  3Q0K A;  3SOG A;  3SYV A;  3ACO A;  4DCN C;  2Z0N A;  3QE6 A;  1I49 A;  3Q84 A;  2FIC A;  3HAJ A;  3LLL A;  2Q12 A;  4AVM A;  3G9G A;  4WPC A;  4AKV A;  2Q13 A;  4FZS A;  3M3W A;  2EFK A;  1I4D A;  3I2W A;  3CAZ A;  5C5B A;  2ELB A;  1X04 A;  2Z0V A;  3QNI A;  1ZWW A;  3HAH A;  2D1L A; 
#chains in the Genus database with same CATH topology
 1O7D B;  4IM0 A;  4E81 A;  2GA9 D;  1URU A;  2RAJ A;  2X3V A;  4G6Q A;  3ABH A;  5KBP A;  4F01 A;  1QX1 A;  3Q0K A;  4AZC A;  3QE6 A;  1PS3 A;  4HY9 A;  1MJG A;  4WPC A;  2Z8Y A;  3DX3 A;  4EZQ A;  1YWM A;  4B9Q A;  3CV5 A;  2OO2 A;  4AZ5 A;  2F7P A;  2Q12 A;  4EZR A;  2YIA A;  2OW7 A;  3RPM A;  3ER9 B;  4R5L A;  4WPE A;  1TQU A;  2GAF D;  2D4C A;  2ND1 A;  3DX4 A;  4JN4 A;  3T46 A;  3DPQ A;  2O0I 1;  3A98 A;  4DCN C;  2ND0 A;  3OHX M;  4NPH A;  4AZH A;  3Q84 A;  4EZO A;  4EZY A;  4FZS A;  2YL5 A;  1ZWW A;  3HAH A;  2EWF A;  2MI7 A;  3HAI A;  3RV0 A;  3L3O M;  2PY6 A;  3T49 A;  4AZB A;  3KAV A;  2ZXQ A;  1SU7 A;  4EZP A;  3BVU A;  2ELB A;  1X04 A;  4UDX X;  3CZN A;  4H8S A;  2QFF A;  4KIK A;  4UDY X;  1W9M A;  4R5K A;  2YI9 A;  2X3W A;  3D4Y A;  2PMR A;  3T47 A;  4AKV A;  3D4Z A;  5FIG A;  4JWE A;  2QXL A;  2GF4 A;  3SOG A;  1SUF A;  4H6H A;  4NQI A;  4ATM A;  1TQT A;  2YKT A;  4EZV A;  1GNT A;  1TQV A;  2OW6 A;  3EJQ A;  3ACO A;  1QWU A;  4EZX A;  3CZS A;  1GNL A;  1E1D A;  4D8J A;  2NCZ A;  2EX3 B;  3O3N B;  5FLE X;  3DX2 A;  2YI8 A;  1JQK A;  2RAI A;  3RV1 A;  3VEA A;  3DDF A;  4HR1 B;  1ZYL A;  4R5J A;  4AZI A;  2F1B A;  2FIC A;  3LLL A;  1E2U A;  4R5G A;  3PLT A;  2V0O A;  3L3P A;  1R5E A;  3VKH A;  3QWE A;  3D51 A;  5TKY A;  3VEB A;  3LVT A;  5C5B B;  1X03 A;  3SYV A;  3KAW A;  2F1A A;  3EJU A;  4AVM A;  2YIV X;  3M3W A;  3EJT A;  2Z0V A;  3QNI A;  2D1L A;  4FZO A;  1I4L A;  4EZN A;  2YL8 A;  3DX0 A;  4AZ7 A;  2WYH A;  3BUB A;  4JWC A;  1I4T A;  3I39 X;  1HWW A;  3BUP A;  2Z0N A;  3BUQ A;  3UIT A;  4AZ6 A;  2Q13 A;  1O7D C;  2YL9 A;  1U00 A;  4R5I A;  3O3M B;  3DYT A;  1TQW A;  2RAK A;  3BVV A;  1HTY A;  3ER8 C;  1OA1 A;  2OBL A;  3QNJ A;  2WIN M;  4HYB A;  3B51 X;  3BUI A;  3CAZ A;  3KDR A;  1LQ7 A;  2Z0O A;  2YLA A;  1SU8 A;  1Y2O A;  2RT6 A;  1QWN A;  3EJS A;  3D52 A;  3BVW A;  4EZZ A;  3BLB A;  1R34 A;  2KHO A;  3DDG A;  3D50 A;  3EJR A;  3I2W A;  2YL6 A;  3DPP A;  2JNK A;  4BNE A;  2JNS A;  4E3C A;  2N3K A;  4JWD A;  1WDZ A;  2X3X A;  1GN9 A;  4F00 A;  1HXK A;  1UPX A;  2YLL A;  1SU6 A;  3GI7 A;  4IM3 A;  4FZP A;  3D2F A;  1I49 A;  3HAJ A;  3G9G A;  2WYI A;  4KIK B;  4IWQ A;  2EFK A;  4IWP A;  3EJP A;  3ERC C;  4JNF A;  3B52 X;  3DPO A;  4JNE A;  4AZG A;  3DX1 A;  4NSW A;  2OBM A;  4PO2 A;  3OWG A;  3BUD A;  1E9V A;  4IM2 A;  3D2E A;  3T48 A;  4EZW A;  4JL9 A;  4AZC B;  2LXY A;  3FD9 A;  4FM3 A;  1OAO A;  4JLC A;  2X5C A;  2F7Q A;  1DKY A;  2YIB A;  1I4D A;  4H6I A;  2OZN B;  4M0M A;  3C7N A;  4IWO A;  2QKW A;  1OA0 A;  3OK8 A;  4EZT A;  1DKX A;  4I1Q A;  2C08 A;  2FYV A;  3LMF A;  2EFL A;  1DKZ A;  3CKD A;  1TQS A;  3T4A G;  4HR1 A;  4IW0 A;  3BVX A;  5E84 A;  2F7R A;  3ZED A;  3CVR A;  3F7W A;  2F18 A;  2LM0 A;  3B53 X;  4DYL A;  3I04 A;  4JWI A;  3O3O B;  4EZU A;  2ALW A;  4EZS A;  3I01 A;  3QA8 A;  3BVT A;  2F7O A;  5C5B A;  1R33 A; 
#chains in the Genus database with same CATH homology
 1I4L A;  2Z0O A;  4BNE A;  2RAI A;  3OK8 A;  3HAI A;  4H8S A;  4NQI A;  4ATM A;  4DYL A;  1Y2O A;  1URU A;  2RAJ A;  3QWE A;  2X3V A;  2V0O A;  3DYT A;  3PLT A;  2C08 A;  2RAK A;  4I1Q A;  1WDZ A;  4WPE A;  2X3X A;  3ABH A;  4NSW A;  2X3W A;  1I4T A;  2YKT A;  2D4C A;  2EFL A;  5C5B B;  1X03 A;  3Q0K A;  3SOG A;  3SYV A;  3ACO A;  4DCN C;  2Z0N A;  3QE6 A;  1I49 A;  3Q84 A;  2FIC A;  3HAJ A;  3LLL A;  2Q12 A;  4AVM A;  3G9G A;  4WPC A;  4AKV A;  2Q13 A;  4FZS A;  3M3W A;  2EFK A;  1I4D A;  3I2W A;  3CAZ A;  5C5B A;  2ELB A;  1X04 A;  2Z0V A;  3QNI A;  1ZWW A;  3HAH A;  2D1L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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