3QE6A

Mouse pacsin 3 f-bar domain structure
Total Genus 117
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
117
sequence length
290
structure length
283
Chain Sequence
GSFWEAGNYRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLADWARKWRGAVEKGPQYGTLEKAWHAFFTAAERLSELHLEVREKLHGPDSERVRTWQRGAFHRPVLGGFRESRAAEDGFRKAQKPWLKRLKEVEASKKSYHTARKDEKTAQTRESHAQEQLRKLQERVGRCTKEAEKMKTQYEQTLAELNRYTPRYMEDMEQAFESCQAAERQRLLFFKDVLLTLHQHLDLSSSDKFHELHRDLQQSIEAASDEEDLRWWRSTHGPGMAMNWPQFEEWS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Rigidity of wedge loop in PACSIN 3 protein is a key factor in dictating diameters of tubules
pubmed doi rcsb
molecule tags Endocytosis
source organism Mus musculus
molecule keywords Protein kinase C and casein kinase II substrate protein 3
total genus 117
structure length 283
sequence length 290
chains with identical sequence B
ec nomenclature
pdb deposition date 2011-01-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3qe6A01
1URUA 2D4CA 2V0OA 2Z0OA 4AKVA 4H8SA 1ZWWA 3Q0KA 3OK8A 2X3WA 3ABHA 5C5BA 1Y2OA 3G9GA 1X03A 1X04A 2ELBA 2X3VA 4WPCA 2Q13A 5C5BB 1I4DA 3QWEA 4DCNC 2EFKA 3HAIA 3SYVA 4NQIA 3LLLA 3QNIA 4NSWA 4AVMA 4WPEA 1I4LA 2C08A 2D1LA 2Z0NA 2Z0VA 3HAHA 3I2WA 4FZSA 4I1QA 2RAKA 2YKTA 2X3XA 3M3WA 2FICA 3PLTA 3HAJA 2RAIA 1I49A 2EFLA 1WDZA 3SOGA 3DYTA 3QE6A 3Q84A 4DYLA 4BNEA 3CAZA 3ACOA 4ATMA 2Q12A 2RAJA 1I4TA
chains in the Genus database with same CATH superfamily
4R5KA 4H8SA 5C5BA 3FD9A 2Z8YA 2F7PA 4KIKB 2F7OA 3T49A 3BVTA 4AZCB 4FZPA 3OWGA 2EX3B 3Q0KA 2FYVA 1GN9A 3BVWA 1PS3A 3BUIA 3RV1A 4EZQA 3I04A 1GNTA 1R33A 3EJSA 2OW6A 4IWQA 3CZNA 3PLTA 2N3KA 1E1DA 1OA1A 4IM2A 3BVVA 2Q12A 1E9VA 1HXKA 3D4YA 3B52X 1DKZA 2ELBA 3DDGA 4DCNC 3SYVA 3ER9B 4F00A 2D1LA 1OA0A 3D51A 3O3NB 2WYHA 2X3XA 1O7DC 3D4ZA 3CV5A 3VEAA 1TQUA 3L3OM 3O3OB 3T4AG 5KBPA 2X3VA 2EFKA 4EZZA 1TQWA 3DPQA 3I2WA 3HAHA 4HY9A 2OZNB 1SUFA 4JNEA 2FICA 4IM3A 3ERCC 2YL8A 3SOGA 1JQKA 2WYIA 2OO2A 2Q13A 1W9MA 2F1AA 4IW0A 2YI8A 4R5JA 4AZIA 1LQ7A 3DX1A 3OK8A 3LVTA 4UDYX 4AZ5A 3A98A 1QWNA 1SU6A 3DX4A 3HAIA 4AZ7A 1TQSA 4NSWA 2MI7A 3B53X 3M3WA 1SU7A 3BUQA 4FZOA 1DKXA 3RV0A 5FLEX 1X03A 3D2FA 4R5LA 3T47A 1QX1A 3QWEA 4EZYA 3LLLA 4HR1A 3EJTA 3BLBA 3KAVA 2X5CA 3D52A 1R34A 3QE6A 4AZBA 1TQTA 3QNJA 4JWCA 2GAFD 2RAJA 1OAOA 2V0OA 3DX2A 4D8JA 4PO2A 4EZTA 4E81A 4M0MA 3EJQA 2LXYA 3QNIA 1O7DB 2PMRA 2RT6A 4AZCA 3B51X 3ZEDA 3HAJA 1QWUA 2YL6A 4IWOA 4AZHA 2LM0A 3VEBA 3D50A 1ZWWA 2X3WA 1Y2OA 3O3MB 1ZYLA 1U00A 4AVMA 3EJPA 2QKWA 1WDZA 1UPXA 2D4CA 4FM3A 3ABHA 3RPMA 4UDXX 3T46A 4EZOA 3L3PA 4JN4A 5C5BB 2JNSA 1I4DA 2ND1A 3BUBA 2YKTA 4EZWA 3CKDA 3BUDA 4E3CA 3DDFA 4ATMA 5E84A 2GA9D 5FIGA 3I01A 3UITA 3DX0A 4EZVA 3EJRA 2EWFA 3ER8C 2YIVX 1E2UA 2PY6A 4EZRA 4WPCA 4JWIA 3BVXA 4FZSA 2YL5A 4I1QA 4JLCA 3Q84A 4BNEA 4JNFA 4JL9A 1URUA 2Z0OA 3QA8A 2F1BA 4EZXA 4EZSA 1R5EA 4R5GA 3OHXM 3GI7A 1GNLA 4WPEA 2NCZA 2RAIA 1I49A 2ZXQA 3BVUA 4JWEA 1YWMA 2OBLA 1TQVA 4G6QA 2F18A 3DPPA 4AZGA 2YI9A 4F01A 4KIKA 1DKYA 4B9QA 2OBMA 3DYTA 4EZPA 1MJGA 2OW7A 1I4TA 4DYLA 2GF4A 3CVRA 3KDRA 3DX3A 3G9GA 3CZSA 1X04A 3D2EA 4AZ6A 4HYBA 1SU8A 2QFFA 2C08A 2F7QA 4H6IA 2Z0NA 3KAWA 2RAKA 4NPHA 2EFLA 3DPOA 3I39X 1HWWA 2YLAA 3ACOA 3C7NA 1HTYA 4AKVA 2YIBA 4R5IA 4IWPA 2O0I1 3LMFA 4NQIA 2QXLA 2Z0VA 3VKHA 3F7WA 2JNKA 2KHOA 3BUPA 4H6HA 4EZNA 2F7RA 4IM0A 2ND0A 2YLLA 5TKYA 1I4LA 2YIAA 3EJUA 4EZUA 3T48A 4HR1B 2YL9A 4JWDA 2ALWA 3CAZA 2WINM
chains in the Genus database with same CATH topology
1URUA 2D4CA 2V0OA 2Z0OA 4AKVA 4H8SA 1ZWWA 3Q0KA 3OK8A 2X3WA 3ABHA 5C5BA 1Y2OA 3G9GA 1X03A 1X04A 2ELBA 2X3VA 4WPCA 2Q13A 5C5BB 1I4DA 3QWEA 4DCNC 2EFKA 3HAIA 3SYVA 4NQIA 3LLLA 3QNIA 4NSWA 4AVMA 4WPEA 1I4LA 2C08A 2D1LA 2Z0NA 2Z0VA 3HAHA 3I2WA 4FZSA 4I1QA 2RAKA 2YKTA 2X3XA 3M3WA 2FICA 3PLTA 3HAJA 2RAIA 1I49A 2EFLA 1WDZA 3SOGA 3DYTA 3QE6A 3Q84A 4DYLA 4BNEA 3CAZA 3ACOA 4ATMA 2Q12A 2RAJA 1I4TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1URU A;  2D4C A;  2V0O A;  2Z0O A;  4AKV A;  4H8S A;  1ZWW A;  3Q0K A;  3OK8 A;  2X3W A;  3ABH A;  5C5B A;  1Y2O A;  3G9G A;  1X03 A;  1X04 A;  2ELB A;  2X3V A;  4WPC A;  2Q13 A;  5C5B B;  1I4D A;  3QWE A;  4DCN C;  2EFK A;  3HAI A;  3SYV A;  4NQI A;  3LLL A;  3QNI A;  4NSW A;  4AVM A;  4WPE A;  1I4L A;  2C08 A;  2D1L A;  2Z0N A;  2Z0V A;  3HAH A;  3I2W A;  4FZS A;  4I1Q A;  2RAK A;  2YKT A;  2X3X A;  3M3W A;  2FIC A;  3PLT A;  3HAJ A;  2RAI A;  1I49 A;  2EFL A;  1WDZ A;  3SOG A;  3DYT A;  3QE6 A;  3Q84 A;  4DYL A;  4BNE A;  3CAZ A;  3ACO A;  4ATM A;  2Q12 A;  2RAJ A;  1I4T A; 
#chains in the Genus database with same CATH topology
 4R5K A;  4H8S A;  5C5B A;  3FD9 A;  2Z8Y A;  2F7P A;  4KIK B;  2F7O A;  3T49 A;  3BVT A;  4AZC B;  4FZP A;  3OWG A;  2EX3 B;  3Q0K A;  2FYV A;  1GN9 A;  3BVW A;  1PS3 A;  3BUI A;  3RV1 A;  4EZQ A;  3I04 A;  1GNT A;  1R33 A;  3EJS A;  2OW6 A;  4IWQ A;  3CZN A;  3PLT A;  2N3K A;  1E1D A;  1OA1 A;  4IM2 A;  3BVV A;  2Q12 A;  1E9V A;  1HXK A;  3D4Y A;  3B52 X;  1DKZ A;  2ELB A;  3DDG A;  4DCN C;  3SYV A;  3ER9 B;  4F00 A;  2D1L A;  1OA0 A;  3D51 A;  3O3N B;  2WYH A;  2X3X A;  1O7D C;  3D4Z A;  3CV5 A;  3VEA A;  1TQU A;  3L3O M;  3O3O B;  3T4A G;  5KBP A;  2X3V A;  2EFK A;  4EZZ A;  1TQW A;  3DPQ A;  3I2W A;  3HAH A;  4HY9 A;  2OZN B;  1SUF A;  4JNE A;  2FIC A;  4IM3 A;  3ERC C;  2YL8 A;  3SOG A;  1JQK A;  2WYI A;  2OO2 A;  2Q13 A;  1W9M A;  2F1A A;  4IW0 A;  2YI8 A;  4R5J A;  4AZI A;  1LQ7 A;  3DX1 A;  3OK8 A;  3LVT A;  4UDY X;  4AZ5 A;  3A98 A;  1QWN A;  1SU6 A;  3DX4 A;  3HAI A;  4AZ7 A;  1TQS A;  4NSW A;  2MI7 A;  3B53 X;  3M3W A;  1SU7 A;  3BUQ A;  4FZO A;  1DKX A;  3RV0 A;  5FLE X;  1X03 A;  3D2F A;  4R5L A;  3T47 A;  1QX1 A;  3QWE A;  4EZY A;  3LLL A;  4HR1 A;  3EJT A;  3BLB A;  3KAV A;  2X5C A;  3D52 A;  1R34 A;  3QE6 A;  4AZB A;  1TQT A;  3QNJ A;  4JWC A;  2GAF D;  2RAJ A;  1OAO A;  2V0O A;  3DX2 A;  4D8J A;  4PO2 A;  4EZT A;  4E81 A;  4M0M A;  3EJQ A;  2LXY A;  3QNI A;  1O7D B;  2PMR A;  2RT6 A;  4AZC A;  3B51 X;  3ZED A;  3HAJ A;  1QWU A;  2YL6 A;  4IWO A;  4AZH A;  2LM0 A;  3VEB A;  3D50 A;  1ZWW A;  2X3W A;  1Y2O A;  3O3M B;  1ZYL A;  1U00 A;  4AVM A;  3EJP A;  2QKW A;  1WDZ A;  1UPX A;  2D4C A;  4FM3 A;  3ABH A;  3RPM A;  4UDX X;  3T46 A;  4EZO A;  3L3P A;  4JN4 A;  5C5B B;  2JNS A;  1I4D A;  2ND1 A;  3BUB A;  2YKT A;  4EZW A;  3CKD A;  3BUD A;  4E3C A;  3DDF A;  4ATM A;  5E84 A;  2GA9 D;  5FIG A;  3I01 A;  3UIT A;  3DX0 A;  4EZV A;  3EJR A;  2EWF A;  3ER8 C;  2YIV X;  1E2U A;  2PY6 A;  4EZR A;  4WPC A;  4JWI A;  3BVX A;  4FZS A;  2YL5 A;  4I1Q A;  4JLC A;  3Q84 A;  4BNE A;  4JNF A;  4JL9 A;  1URU A;  2Z0O A;  3QA8 A;  2F1B A;  4EZX A;  4EZS A;  1R5E A;  4R5G A;  3OHX M;  3GI7 A;  1GNL A;  4WPE A;  2NCZ A;  2RAI A;  1I49 A;  2ZXQ A;  3BVU A;  4JWE A;  1YWM A;  2OBL A;  1TQV A;  4G6Q A;  2F18 A;  3DPP A;  4AZG A;  2YI9 A;  4F01 A;  4KIK A;  1DKY A;  4B9Q A;  2OBM A;  3DYT A;  4EZP A;  1MJG A;  2OW7 A;  1I4T A;  4DYL A;  2GF4 A;  3CVR A;  3KDR A;  3DX3 A;  3G9G A;  3CZS A;  1X04 A;  3D2E A;  4AZ6 A;  4HYB A;  1SU8 A;  2QFF A;  2C08 A;  2F7Q A;  4H6I A;  2Z0N A;  3KAW A;  2RAK A;  4NPH A;  2EFL A;  3DPO A;  3I39 X;  1HWW A;  2YLA A;  3ACO A;  3C7N A;  1HTY A;  4AKV A;  2YIB A;  4R5I A;  4IWP A;  2O0I 1;  3LMF A;  4NQI A;  2QXL A;  2Z0V A;  3VKH A;  3F7W A;  2JNK A;  2KHO A;  3BUP A;  4H6H A;  4EZN A;  2F7R A;  4IM0 A;  2ND0 A;  2YLL A;  5TKY A;  1I4L A;  2YIA A;  3EJU A;  4EZU A;  3T48 A;  4HR1 B;  2YL9 A;  4JWD A;  2ALW A;  3CAZ A;  2WIN M; 
#chains in the Genus database with same CATH homology
 1URU A;  2D4C A;  2V0O A;  2Z0O A;  4AKV A;  4H8S A;  1ZWW A;  3Q0K A;  3OK8 A;  2X3W A;  3ABH A;  5C5B A;  1Y2O A;  3G9G A;  1X03 A;  1X04 A;  2ELB A;  2X3V A;  4WPC A;  2Q13 A;  5C5B B;  1I4D A;  3QWE A;  4DCN C;  2EFK A;  3HAI A;  3SYV A;  4NQI A;  3LLL A;  3QNI A;  4NSW A;  4AVM A;  4WPE A;  1I4L A;  2C08 A;  2D1L A;  2Z0N A;  2Z0V A;  3HAH A;  3I2W A;  4FZS A;  4I1Q A;  2RAK A;  2YKT A;  2X3X A;  3M3W A;  2FIC A;  3PLT A;  3HAJ A;  2RAI A;  1I49 A;  2EFL A;  1WDZ A;  3SOG A;  3DYT A;  3QE6 A;  3Q84 A;  4DYL A;  4BNE A;  3CAZ A;  3ACO A;  4ATM A;  2Q12 A;  2RAJ A;  1I4T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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