3QNIA

Crystal structure of human pacsin 1 f-bar domain
Total Genus 110
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
110
sequence length
293
structure length
273
Chain Sequence
TTDSFWEVGNYKRTVKRIDDGHRLCNDLMNCVQERAKIEKAYGQQLTDWAKRWRQLIEKGPQYGSLERAWGAIMTEADKVSELHQEVKNNLLNEDLEKVKNWQKDAYHKQIMGGFKETKEAEDGFRKAQKPWAKKMKELEAAKKAYHLACKEEKLAMQDKVDKCKQDVQKTQEKYEKVLEDVGKTTPQYMENMEQVFEQCQQFEEKRLVFLKEVLLDIKRHLNLAENSSYIHVYRELEQAIRGADAQEDLRWFRSTSGPGMPMNWPQFEEWNP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of human PACSIN 1 F-BAR domain
rcsb
molecule tags Endocytosis
source organism Homo sapiens
molecule keywords Protein kinase C and casein kinase substrate in neurons prot
total genus 110
structure length 273
sequence length 293
chains with identical sequence B
ec nomenclature
pdb deposition date 2011-02-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3qniA01
3Q0KA 1ZWWA 4I1QA 3SOGA 4NSWA 3SYVA 2FICA 3Q84A 3HAIA 2X3WA 3CAZA 3ACOA 3LLLA 4AVMA 1Y2OA 2Z0NA 2X3VA 2V0OA 3HAHA 4BNEA 3I2WA 2RAKA 3OK8A 2X3XA 4NQIA 2EFKA 4AKVA 1WDZA 5C5BB 3ABHA 2EFLA 3QE6A 1I4TA 4DCNC 3PLTA 4FZSA 3QNIA 1URUA 2Q13A 2D1LA 2C08A 3DYTA 3G9GA 4WPCA 2D4CA 4ATMA 4DYLA 1I4LA 2ELBA 2Q12A 1X03A 2RAIA 2Z0VA 1I4DA 3HAJA 2YKTA 5C5BA 3M3WA 2RAJA 2Z0OA 4WPEA 1I49A 3QWEA 1X04A 4H8SA
chains in the Genus database with same CATH superfamily
2F7QA 4IM0A 2YI9A 3C7NA 1SU7A 4EZXA 3EJRA 3RV0A 2WYHA 3QE6A 1GN9A 4AZGA 1HWWA 1I4LA 3FD9A 1OAOA 4B9QA 2NCZA 4R5IA 2WYIA 1TQSA 3ERCC 3O3MB 5FLEX 3KAWA 4HR1B 2N3KA 4IM2A 4E3CA 2RAIA 4H6IA 4NSWA 3HAIA 4JN4A 3T46A 4UDYX 3CV5A 2QXLA 1SUFA 2EFKA 4R5KA 1U00A 1MJGA 1TQTA 1X04A 4H8SA 3Q0KA 3SYVA 4JWDA 4AVMA 2F1BA 3BVTA 3DX1A 3D52A 4FZPA 2C08A 3QA8A 2F7OA 3OWGA 3B51X 4R5GA 1X03A 1E1DA 4WPEA 1O7DC 3EJTA 3SOGA 1E2UA 1R33A 3BUBA 1QX1A 4EZNA 3KDRA 3OK8A 4NQIA 3D51A 4EZOA 1TQWA 1YWMA 3CKDA 3PLTA 2EX3B 1OA0A 2O0I1 2WINM 1ZWWA 2FICA 3D2EA 1DKZA 1O7DB 1DKYA 1HTYA 4EZYA 3I39X 2OW6A 3T48A 4M0MA 3BUIA 4R5JA 4JWCA 4IM3A 2JNSA 4EZPA 2OO2A 3VKHA 4EZRA 2Q13A 2ELBA 3CZSA 3DDFA 1W9MA 1DKXA 4IW0A 3DX3A 4I1QA 2YLAA 3ACOA 3RPMA 4IWPA 2RAKA 4JWIA 2PMRA 2ZXQA 1SU6A 3ABHA 1TQUA 1URUA 3D4ZA 1GNTA 1R5EA 3BVVA 5KBPA 4E81A 1E9VA 3L3PA 3GI7A 2OBLA 2GA9D 4AZHA 1HXKA 3QNJA 3LVTA 3LLLA 2OBMA 2X5CA 3F7WA 1QWNA 4JL9A 2FYVA 4AKVA 1WDZA 4R5LA 3EJUA 2F1AA 1OA1A 4AZBA 3T4AG 2Q12A 3DX2A 5C5BA 3DPOA 4PO2A 2ALWA 3D4YA 2F18A 3Q84A 2GAFD 2GF4A 2X3WA 2YL9A 4KIKA 3BUPA 1LQ7A 4AZCA 2X3VA 2OZNB 2LXYA 4FM3A 3OHXM 3O3OB 3ZEDA 4FZSA 4WPCA 2F7RA 1TQVA 4DCNC 2ND0A 1Y2OA 3DPPA 4BNEA 3B52X 2JNKA 5C5BB 3BVWA 2QKWA 2YLLA 4AZ6A 2D4CA 3I01A 3A98A 3D2FA 2RAJA 4UDXX 4EZWA 1JQKA 2YIVX 3O3NB 3KAVA 3BUDA 2ND1A 3EJSA 2V0OA 3LMFA 2X3XA 3L3OM 4JNEA 1I4TA 3DPQA 4EZSA 2YIAA 4FZOA 4DYLA 2F7PA 2Z0VA 1I4DA 2RT6A 1I49A 5TKYA 4F01A 4IWQA 4NPHA 3EJPA 3CVRA 1R34A 3QNIA 3G9GA 3VEBA 3BLBA 1SU8A 2YL8A 3DDGA 3BUQA 2YKTA 2Z0OA 3UITA 4EZQA 2YIBA 3RV1A 2Z0NA 3CZNA 3DYTA 3BVUA 4JWEA 2KHOA 2PY6A 1PS3A 3QWEA 3D50A 3DX0A 3DX4A 2YL6A 2Z8YA 3VEAA 4JNFA 2EWFA 4G6QA 4HYBA 4ATMA 5FIGA 3M3WA 2MI7A 1ZYLA 2OW7A 4EZUA 3ER9B 4HY9A 2LM0A 4AZ7A 4EZVA 3EJQA 5E84A 4AZIA 3T49A 2QFFA 2YL5A 4EZZA 4D8JA 4H6HA 4AZ5A 1UPXA 3HAJA 4KIKB 4AZCB 3T47A 4IWOA 3ER8C 4F00A 3B53X 3I04A 3CAZA 1QWUA 4JLCA 3HAHA 3I2WA 2EFLA 3BVXA 2D1LA 4EZTA 2YI8A 1GNLA 4HR1A
chains in the Genus database with same CATH topology
3Q0KA 1ZWWA 4I1QA 3SOGA 4NSWA 3SYVA 2FICA 3Q84A 3HAIA 2X3WA 3CAZA 3ACOA 3LLLA 4AVMA 1Y2OA 2Z0NA 2X3VA 2V0OA 3HAHA 4BNEA 3I2WA 2RAKA 3OK8A 2X3XA 4NQIA 2EFKA 4AKVA 1WDZA 5C5BB 3ABHA 2EFLA 3QE6A 1I4TA 4DCNC 3PLTA 4FZSA 3QNIA 1URUA 2Q13A 2D1LA 2C08A 3DYTA 3G9GA 4WPCA 2D4CA 4ATMA 4DYLA 1I4LA 2ELBA 2Q12A 1X03A 2RAIA 2Z0VA 1I4DA 3HAJA 2YKTA 5C5BA 3M3WA 2RAJA 2Z0OA 4WPEA 1I49A 3QWEA 1X04A 4H8SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3Q0K A;  1ZWW A;  4I1Q A;  3SOG A;  4NSW A;  3SYV A;  2FIC A;  3Q84 A;  3HAI A;  2X3W A;  3CAZ A;  3ACO A;  3LLL A;  4AVM A;  1Y2O A;  2Z0N A;  2X3V A;  2V0O A;  3HAH A;  4BNE A;  3I2W A;  2RAK A;  3OK8 A;  2X3X A;  4NQI A;  2EFK A;  4AKV A;  1WDZ A;  5C5B B;  3ABH A;  2EFL A;  3QE6 A;  1I4T A;  4DCN C;  3PLT A;  4FZS A;  3QNI A;  1URU A;  2Q13 A;  2D1L A;  2C08 A;  3DYT A;  3G9G A;  4WPC A;  2D4C A;  4ATM A;  4DYL A;  1I4L A;  2ELB A;  2Q12 A;  1X03 A;  2RAI A;  2Z0V A;  1I4D A;  3HAJ A;  2YKT A;  5C5B A;  3M3W A;  2RAJ A;  2Z0O A;  4WPE A;  1I49 A;  3QWE A;  1X04 A;  4H8S A; 
#chains in the Genus database with same CATH topology
 2F7Q A;  4IM0 A;  2YI9 A;  3C7N A;  1SU7 A;  4EZX A;  3EJR A;  3RV0 A;  2WYH A;  3QE6 A;  1GN9 A;  4AZG A;  1HWW A;  1I4L A;  3FD9 A;  1OAO A;  4B9Q A;  2NCZ A;  4R5I A;  2WYI A;  1TQS A;  3ERC C;  3O3M B;  5FLE X;  3KAW A;  4HR1 B;  2N3K A;  4IM2 A;  4E3C A;  2RAI A;  4H6I A;  4NSW A;  3HAI A;  4JN4 A;  3T46 A;  4UDY X;  3CV5 A;  2QXL A;  1SUF A;  2EFK A;  4R5K A;  1U00 A;  1MJG A;  1TQT A;  1X04 A;  4H8S A;  3Q0K A;  3SYV A;  4JWD A;  4AVM A;  2F1B A;  3BVT A;  3DX1 A;  3D52 A;  4FZP A;  2C08 A;  3QA8 A;  2F7O A;  3OWG A;  3B51 X;  4R5G A;  1X03 A;  1E1D A;  4WPE A;  1O7D C;  3EJT A;  3SOG A;  1E2U A;  1R33 A;  3BUB A;  1QX1 A;  4EZN A;  3KDR A;  3OK8 A;  4NQI A;  3D51 A;  4EZO A;  1TQW A;  1YWM A;  3CKD A;  3PLT A;  2EX3 B;  1OA0 A;  2O0I 1;  2WIN M;  1ZWW A;  2FIC A;  3D2E A;  1DKZ A;  1O7D B;  1DKY A;  1HTY A;  4EZY A;  3I39 X;  2OW6 A;  3T48 A;  4M0M A;  3BUI A;  4R5J A;  4JWC A;  4IM3 A;  2JNS A;  4EZP A;  2OO2 A;  3VKH A;  4EZR A;  2Q13 A;  2ELB A;  3CZS A;  3DDF A;  1W9M A;  1DKX A;  4IW0 A;  3DX3 A;  4I1Q A;  2YLA A;  3ACO A;  3RPM A;  4IWP A;  2RAK A;  4JWI A;  2PMR A;  2ZXQ A;  1SU6 A;  3ABH A;  1TQU A;  1URU A;  3D4Z A;  1GNT A;  1R5E A;  3BVV A;  5KBP A;  4E81 A;  1E9V A;  3L3P A;  3GI7 A;  2OBL A;  2GA9 D;  4AZH A;  1HXK A;  3QNJ A;  3LVT A;  3LLL A;  2OBM A;  2X5C A;  3F7W A;  1QWN A;  4JL9 A;  2FYV A;  4AKV A;  1WDZ A;  4R5L A;  3EJU A;  2F1A A;  1OA1 A;  4AZB A;  3T4A G;  2Q12 A;  3DX2 A;  5C5B A;  3DPO A;  4PO2 A;  2ALW A;  3D4Y A;  2F18 A;  3Q84 A;  2GAF D;  2GF4 A;  2X3W A;  2YL9 A;  4KIK A;  3BUP A;  1LQ7 A;  4AZC A;  2X3V A;  2OZN B;  2LXY A;  4FM3 A;  3OHX M;  3O3O B;  3ZED A;  4FZS A;  4WPC A;  2F7R A;  1TQV A;  4DCN C;  2ND0 A;  1Y2O A;  3DPP A;  4BNE A;  3B52 X;  2JNK A;  5C5B B;  3BVW A;  2QKW A;  2YLL A;  4AZ6 A;  2D4C A;  3I01 A;  3A98 A;  3D2F A;  2RAJ A;  4UDX X;  4EZW A;  1JQK A;  2YIV X;  3O3N B;  3KAV A;  3BUD A;  2ND1 A;  3EJS A;  2V0O A;  3LMF A;  2X3X A;  3L3O M;  4JNE A;  1I4T A;  3DPQ A;  4EZS A;  2YIA A;  4FZO A;  4DYL A;  2F7P A;  2Z0V A;  1I4D A;  2RT6 A;  1I49 A;  5TKY A;  4F01 A;  4IWQ A;  4NPH A;  3EJP A;  3CVR A;  1R34 A;  3QNI A;  3G9G A;  3VEB A;  3BLB A;  1SU8 A;  2YL8 A;  3DDG A;  3BUQ A;  2YKT A;  2Z0O A;  3UIT A;  4EZQ A;  2YIB A;  3RV1 A;  2Z0N A;  3CZN A;  3DYT A;  3BVU A;  4JWE A;  2KHO A;  2PY6 A;  1PS3 A;  3QWE A;  3D50 A;  3DX0 A;  3DX4 A;  2YL6 A;  2Z8Y A;  3VEA A;  4JNF A;  2EWF A;  4G6Q A;  4HYB A;  4ATM A;  5FIG A;  3M3W A;  2MI7 A;  1ZYL A;  2OW7 A;  4EZU A;  3ER9 B;  4HY9 A;  2LM0 A;  4AZ7 A;  4EZV A;  3EJQ A;  5E84 A;  4AZI A;  3T49 A;  2QFF A;  2YL5 A;  4EZZ A;  4D8J A;  4H6H A;  4AZ5 A;  1UPX A;  3HAJ A;  4KIK B;  4AZC B;  3T47 A;  4IWO A;  3ER8 C;  4F00 A;  3B53 X;  3I04 A;  3CAZ A;  1QWU A;  4JLC A;  3HAH A;  3I2W A;  2EFL A;  3BVX A;  2D1L A;  4EZT A;  2YI8 A;  1GNL A;  4HR1 A; 
#chains in the Genus database with same CATH homology
 3Q0K A;  1ZWW A;  4I1Q A;  3SOG A;  4NSW A;  3SYV A;  2FIC A;  3Q84 A;  3HAI A;  2X3W A;  3CAZ A;  3ACO A;  3LLL A;  4AVM A;  1Y2O A;  2Z0N A;  2X3V A;  2V0O A;  3HAH A;  4BNE A;  3I2W A;  2RAK A;  3OK8 A;  2X3X A;  4NQI A;  2EFK A;  4AKV A;  1WDZ A;  5C5B B;  3ABH A;  2EFL A;  3QE6 A;  1I4T A;  4DCN C;  3PLT A;  4FZS A;  3QNI A;  1URU A;  2Q13 A;  2D1L A;  2C08 A;  3DYT A;  3G9G A;  4WPC A;  2D4C A;  4ATM A;  4DYL A;  1I4L A;  2ELB A;  2Q12 A;  1X03 A;  2RAI A;  2Z0V A;  1I4D A;  3HAJ A;  2YKT A;  5C5B A;  3M3W A;  2RAJ A;  2Z0O A;  4WPE A;  1I49 A;  3QWE A;  1X04 A;  4H8S A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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