3QWEA

Crystal structure of the n-terminal domain of the gem interacting protein
Total Genus 126
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
126
sequence length
273
structure length
260
Chain Sequence
GEELDLRLIRTKGGVDAALEYAKTWSRYAKELLAWTEKRASYELEFAKSTMKIAEAGKVSIQQQSHMPLQYIYTLFLEHDLSLGTLAMETVAQQKRDYYQPLAAKRTEIEKWRKEFKEQWMKEQKRMNEAVQALRRAQLQYVQRSEDLRARSQGSKQQERRRRSREEAQAKAQEAEALYQACVREANARQQDLEIAKQRIVSHVRKLVFQGDEVLRRVTLSLFGLRGAQAERGPRAFAALAECCAPFEPGQRYQEFVRAL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the N-terminal domain of the GEM interacting protein
rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords GEM-interacting protein
total genus 126
structure length 260
sequence length 273
ec nomenclature
pdb deposition date 2011-02-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3qweA00
3QNIA 2Q12A 5C5BB 2Z0OA 2RAIA 4DYLA 4BNEA 2ELBA 4I1QA 1Y2OA 3SYVA 1X04A 2X3XA 4AKVA 4NSWA 4ATMA 2X3WA 2EFLA 3I2WA 3M3WA 4DCNC 2D1LA 2Z0NA 1URUA 1X03A 1I4DA 3ACOA 1WDZA 3CAZA 3PLTA 4NQIA 3HAJA 3Q0KA 2EFKA 3ABHA 3SOGA 3HAIA 4AVMA 2C08A 3HAHA 3Q84A 4H8SA 3QE6A 3QWEA 5C5BA 2Q13A 1I4LA 3G9GA 2X3VA 3OK8A 2D4CA 4WPEA 2YKTA 2V0OA 3DYTA 2FICA 4WPCA 1ZWWA 2RAJA 2Z0VA 1I49A 3LLLA 1I4TA 4FZSA 2RAKA
chains in the Genus database with same CATH superfamily
4D8JA 2OO2A 1JQKA 3DX0A 4EZRA 1TQTA 1OAOA 1R34A 3BUDA 1TQWA 4HR1B 2F7RA 2YI9A 1HTYA 3T48A 2RT6A 4FZPA 4FM3A 2OW7A 2F7PA 3F7WA 3B52X 2OBLA 3BVUA 3RPMA 4JWIA 1OA1A 3DX4A 3BVTA 3BUQA 3T49A 1YWMA 4JNFA 2ND1A 1O7DC 4AZCB 2D4CA 3LLLA 2F1BA 2JNSA 2O0I1 2F7QA 4BNEA 4R5JA 4H6HA 4EZPA 4HY9A 4JWEA 1SU7A 4R5GA 1WDZA 4JNEA 3L3PA 1R33A 3OHXM 2F1AA 2QKWA 2EWFA 3D4YA 2KHOA 2ND0A 1E1DA 3QNIA 4IM0A 4I1QA 3SYVA 4NSWA 4DCNC 4HR1A 1O7DB 3ER9B 3DX3A 2YL9A 3BVVA 3BLBA 2Z8YA 3DX1A 4EZOA 3RV0A 2OW6A 1Y2OA 3O3OB 4ATMA 2EFLA 4R5KA 4AZCA 3CV5A 3FD9A 3CAZA 4M0MA 1HXKA 4EZNA 1HWWA 4IWPA 2JNKA 2YI8A 4AZGA 1U00A 1X04A 2X3XA 3VEBA 3OWGA 4JN4A 1MJGA 2OZNB 2PMRA 3T47A 4AVMA 2F7OA 3O3MB 3DPQA 3ZEDA 3C7NA 3ERCC 4IWOA 3I2WA 3KAVA 4EZYA 1ZYLA 3ACOA 3DPOA 2GF4A 4NPHA 3RV1A 3HAJA 3GI7A 1E9VA 2GA9D 3I04A 3DPPA 1QWNA 4EZQA 4JWCA 4G6QA 4AZ5A 2Z0OA 1SUFA 2Q12A 4DYLA 2F18A 4UDXX 3D2EA 3M3WA 4IWQA 1W9MA 2YLAA 1SU6A 1UPXA 1TQUA 3ABHA 2QXLA 2YL6A 2YKTA 1ZWWA 3D50A 1TQVA 3T4AG 2YL8A 4EZTA 4EZVA 3VEAA 2ALWA 5TKYA 4EZUA 4HYBA 4NQIA 3DDFA 4UDYX 3CVRA 4JLCA 2C08A 1DKYA 2X3VA 2RAJA 3B51X 4EZXA 3A98A 1GN9A 1TQSA 3B53X 3QA8A 5KBPA 1DKZA 3EJPA 4JL9A 2FICA 2YLLA 2N3KA 5C5BB 2WYHA 3BUBA 2X3WA 3ER8C 3BUIA 3BVXA 1X03A 2NCZA 2FYVA 3CKDA 4AZ7A 4IM2A 2EX3B 4KIKB 3D2FA 3I01A 3EJRA 4WPCA 1I4TA 4F01A 4FZSA 3O3NB 2WYIA 1OA0A 3KDRA 2ZXQA 4E3CA 2YIVX 3T46A 5FLEX 1QX1A 4JWDA 3PLTA 3L3OM 2LXYA 3EJTA 3QWEA 1E2UA 2RAKA 5E84A 3D51A 4R5LA 2LM0A 3CZNA 3UITA 2PY6A 4AKVA 4B9QA 3LMFA 3SOGA 4H8SA 5C5BA 1R5EA 2V0OA 2YL5A 4AZHA 4EZWA 3D4ZA 4AZBA 5FIGA 2D1LA 1QWUA 2Z0NA 1URUA 4KIKA 1GNLA 3CZSA 3DX2A 1GNTA 4H6IA 4F00A 3KAWA 1DKXA 4AZIA 4AZ6A 3HAIA 4IM3A 3D52A 2YIBA 4EZZA 4EZSA 1LQ7A 1I4DA 4IW0A 3Q0KA 2GAFD 3EJQA 3Q84A 3G9GA 1I4LA 3OK8A 4WPEA 2YIAA 3EJUA 2Z0VA 1I49A 2X5CA 2OBMA 3DDGA 3VKHA 2WINM 2RAIA 3QNJA 2ELBA 3EJSA 2MI7A 1PS3A 4PO2A 4R5IA 4E81A 2EFKA 4FZOA 3HAHA 3QE6A 3I39X 2Q13A 3LVTA 3BUPA 3DYTA 1SU8A 2QFFA 3BVWA
chains in the Genus database with same CATH topology
3QNIA 2Q12A 5C5BB 2Z0OA 2RAIA 4DYLA 4BNEA 2ELBA 4I1QA 1Y2OA 3SYVA 1X04A 2X3XA 4AKVA 4NSWA 4ATMA 2X3WA 2EFLA 3I2WA 3M3WA 4DCNC 2D1LA 2Z0NA 1URUA 1X03A 1I4DA 3ACOA 1WDZA 3CAZA 3PLTA 4NQIA 3HAJA 3Q0KA 2EFKA 3ABHA 3SOGA 3HAIA 4AVMA 2C08A 3HAHA 3Q84A 4H8SA 3QE6A 3QWEA 5C5BA 2Q13A 1I4LA 3G9GA 2X3VA 3OK8A 2D4CA 4WPEA 2YKTA 2V0OA 3DYTA 2FICA 4WPCA 1ZWWA 2RAJA 2Z0VA 1I49A 3LLLA 1I4TA 4FZSA 2RAKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QNI A;  2Q12 A;  5C5B B;  2Z0O A;  2RAI A;  4DYL A;  4BNE A;  2ELB A;  4I1Q A;  1Y2O A;  3SYV A;  1X04 A;  2X3X A;  4AKV A;  4NSW A;  4ATM A;  2X3W A;  2EFL A;  3I2W A;  3M3W A;  4DCN C;  2D1L A;  2Z0N A;  1URU A;  1X03 A;  1I4D A;  3ACO A;  1WDZ A;  3CAZ A;  3PLT A;  4NQI A;  3HAJ A;  3Q0K A;  2EFK A;  3ABH A;  3SOG A;  3HAI A;  4AVM A;  2C08 A;  3HAH A;  3Q84 A;  4H8S A;  3QE6 A;  3QWE A;  5C5B A;  2Q13 A;  1I4L A;  3G9G A;  2X3V A;  3OK8 A;  2D4C A;  4WPE A;  2YKT A;  2V0O A;  3DYT A;  2FIC A;  4WPC A;  1ZWW A;  2RAJ A;  2Z0V A;  1I49 A;  3LLL A;  1I4T A;  4FZS A;  2RAK A; 
#chains in the Genus database with same CATH topology
 4D8J A;  2OO2 A;  1JQK A;  3DX0 A;  4EZR A;  1TQT A;  1OAO A;  1R34 A;  3BUD A;  1TQW A;  4HR1 B;  2F7R A;  2YI9 A;  1HTY A;  3T48 A;  2RT6 A;  4FZP A;  4FM3 A;  2OW7 A;  2F7P A;  3F7W A;  3B52 X;  2OBL A;  3BVU A;  3RPM A;  4JWI A;  1OA1 A;  3DX4 A;  3BVT A;  3BUQ A;  3T49 A;  1YWM A;  4JNF A;  2ND1 A;  1O7D C;  4AZC B;  2D4C A;  3LLL A;  2F1B A;  2JNS A;  2O0I 1;  2F7Q A;  4BNE A;  4R5J A;  4H6H A;  4EZP A;  4HY9 A;  4JWE A;  1SU7 A;  4R5G A;  1WDZ A;  4JNE A;  3L3P A;  1R33 A;  3OHX M;  2F1A A;  2QKW A;  2EWF A;  3D4Y A;  2KHO A;  2ND0 A;  1E1D A;  3QNI A;  4IM0 A;  4I1Q A;  3SYV A;  4NSW A;  4DCN C;  4HR1 A;  1O7D B;  3ER9 B;  3DX3 A;  2YL9 A;  3BVV A;  3BLB A;  2Z8Y A;  3DX1 A;  4EZO A;  3RV0 A;  2OW6 A;  1Y2O A;  3O3O B;  4ATM A;  2EFL A;  4R5K A;  4AZC A;  3CV5 A;  3FD9 A;  3CAZ A;  4M0M A;  1HXK A;  4EZN A;  1HWW A;  4IWP A;  2JNK A;  2YI8 A;  4AZG A;  1U00 A;  1X04 A;  2X3X A;  3VEB A;  3OWG A;  4JN4 A;  1MJG A;  2OZN B;  2PMR A;  3T47 A;  4AVM A;  2F7O A;  3O3M B;  3DPQ A;  3ZED A;  3C7N A;  3ERC C;  4IWO A;  3I2W A;  3KAV A;  4EZY A;  1ZYL A;  3ACO A;  3DPO A;  2GF4 A;  4NPH A;  3RV1 A;  3HAJ A;  3GI7 A;  1E9V A;  2GA9 D;  3I04 A;  3DPP A;  1QWN A;  4EZQ A;  4JWC A;  4G6Q A;  4AZ5 A;  2Z0O A;  1SUF A;  2Q12 A;  4DYL A;  2F18 A;  4UDX X;  3D2E A;  3M3W A;  4IWQ A;  1W9M A;  2YLA A;  1SU6 A;  1UPX A;  1TQU A;  3ABH A;  2QXL A;  2YL6 A;  2YKT A;  1ZWW A;  3D50 A;  1TQV A;  3T4A G;  2YL8 A;  4EZT A;  4EZV A;  3VEA A;  2ALW A;  5TKY A;  4EZU A;  4HYB A;  4NQI A;  3DDF A;  4UDY X;  3CVR A;  4JLC A;  2C08 A;  1DKY A;  2X3V A;  2RAJ A;  3B51 X;  4EZX A;  3A98 A;  1GN9 A;  1TQS A;  3B53 X;  3QA8 A;  5KBP A;  1DKZ A;  3EJP A;  4JL9 A;  2FIC A;  2YLL A;  2N3K A;  5C5B B;  2WYH A;  3BUB A;  2X3W A;  3ER8 C;  3BUI A;  3BVX A;  1X03 A;  2NCZ A;  2FYV A;  3CKD A;  4AZ7 A;  4IM2 A;  2EX3 B;  4KIK B;  3D2F A;  3I01 A;  3EJR A;  4WPC A;  1I4T A;  4F01 A;  4FZS A;  3O3N B;  2WYI A;  1OA0 A;  3KDR A;  2ZXQ A;  4E3C A;  2YIV X;  3T46 A;  5FLE X;  1QX1 A;  4JWD A;  3PLT A;  3L3O M;  2LXY A;  3EJT A;  3QWE A;  1E2U A;  2RAK A;  5E84 A;  3D51 A;  4R5L A;  2LM0 A;  3CZN A;  3UIT A;  2PY6 A;  4AKV A;  4B9Q A;  3LMF A;  3SOG A;  4H8S A;  5C5B A;  1R5E A;  2V0O A;  2YL5 A;  4AZH A;  4EZW A;  3D4Z A;  4AZB A;  5FIG A;  2D1L A;  1QWU A;  2Z0N A;  1URU A;  4KIK A;  1GNL A;  3CZS A;  3DX2 A;  1GNT A;  4H6I A;  4F00 A;  3KAW A;  1DKX A;  4AZI A;  4AZ6 A;  3HAI A;  4IM3 A;  3D52 A;  2YIB A;  4EZZ A;  4EZS A;  1LQ7 A;  1I4D A;  4IW0 A;  3Q0K A;  2GAF D;  3EJQ A;  3Q84 A;  3G9G A;  1I4L A;  3OK8 A;  4WPE A;  2YIA A;  3EJU A;  2Z0V A;  1I49 A;  2X5C A;  2OBM A;  3DDG A;  3VKH A;  2WIN M;  2RAI A;  3QNJ A;  2ELB A;  3EJS A;  2MI7 A;  1PS3 A;  4PO2 A;  4R5I A;  4E81 A;  2EFK A;  4FZO A;  3HAH A;  3QE6 A;  3I39 X;  2Q13 A;  3LVT A;  3BUP A;  3DYT A;  1SU8 A;  2QFF A;  3BVW A; 
#chains in the Genus database with same CATH homology
 3QNI A;  2Q12 A;  5C5B B;  2Z0O A;  2RAI A;  4DYL A;  4BNE A;  2ELB A;  4I1Q A;  1Y2O A;  3SYV A;  1X04 A;  2X3X A;  4AKV A;  4NSW A;  4ATM A;  2X3W A;  2EFL A;  3I2W A;  3M3W A;  4DCN C;  2D1L A;  2Z0N A;  1URU A;  1X03 A;  1I4D A;  3ACO A;  1WDZ A;  3CAZ A;  3PLT A;  4NQI A;  3HAJ A;  3Q0K A;  2EFK A;  3ABH A;  3SOG A;  3HAI A;  4AVM A;  2C08 A;  3HAH A;  3Q84 A;  4H8S A;  3QE6 A;  3QWE A;  5C5B A;  2Q13 A;  1I4L A;  3G9G A;  2X3V A;  3OK8 A;  2D4C A;  4WPE A;  2YKT A;  2V0O A;  3DYT A;  2FIC A;  4WPC A;  1ZWW A;  2RAJ A;  2Z0V A;  1I49 A;  3LLL A;  1I4T A;  4FZS A;  2RAK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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