3QWEA

Crystal structure of the n-terminal domain of the gem interacting protein
Total Genus 126
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
126
sequence length
273
structure length
260
Chain Sequence
GEELDLRLIRTKGGVDAALEYAKTWSRYAKELLAWTEKRASYELEFAKSTMKIAEAGKVSIQQQSHMPLQYIYTLFLEHDLSLGTLAMETVAQQKRDYYQPLAAKRTEIEKWRKEFKEQWMKEQKRMNEAVQALRRAQLQYVQRSEDLRARSQGSKQQERRRRSREEAQAKAQEAEALYQACVREANARQQDLEIAKQRIVSHVRKLVFQGDEVLRRVTLSLFGLRGAQAERGPRAFAALAECCAPFEPGQRYQEFVRAL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the N-terminal domain of the GEM interacting protein
rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords GEM-interacting protein
total genus 126
structure length 260
sequence length 273
ec nomenclature
pdb deposition date 2011-02-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3qweA00
3QWEA 4I1QA 3HAJA 4H8SA 4BNEA 2Q12A 3G9GA 3CAZA 1I4DA 2FICA 2D4CA 3QNIA 4WPEA 1URUA 4DCNC 3ABHA 2Q13A 1I49A 2X3VA 2Z0OA 2RAKA 3ACOA 3PLTA 2RAIA 2X3XA 2Z0VA 3HAIA 3I2WA 3OK8A 2D1LA 3M3WA 3QE6A 4NSWA 5C5BB 3SYVA 4DYLA 2ELBA 4AVMA 2X3WA 4ATMA 4FZSA 2V0OA 5C5BA 3DYTA 4WPCA 1ZWWA 2C08A 2EFKA 2YKTA 1Y2OA 1I4LA 2Z0NA 3Q0KA 3Q84A 1I4TA 3LLLA 1X03A 1WDZA 1X04A 3HAHA 4NQIA 4AKVA 3SOGA 2EFLA 2RAJA
chains in the Genus database with same CATH superfamily
3O3OB 1HWWA 2LM0A 4PO2A 3BUIA 3L3PA 2FICA 1GNTA 4DCNC 4F01A 2YI8A 1MJGA 3BVUA 1TQUA 4AVMA 3T49A 2YKTA 3OWGA 4R5LA 4R5GA 3L3OM 3QWEA 4EZOA 2PMRA 3EJQA 3OHXM 1SU7A 3G9GA 3BUBA 4AZCA 4JLCA 3B53X 3BLBA 2Z0OA 3ACOA 4HR1B 2ELBA 4JWDA 2V0OA 4AZBA 4AZGA 1LQ7A 3CZSA 3DDFA 2EWFA 4JWCA 2GA9D 1R33A 1R5EA 3ZEDA 4UDYX 4WPEA 2OBMA 3PLTA 5E84A 3QE6A 2GAFD 4DYLA 3BVTA 4FZSA 2F7RA 4E81A 4FZPA 3ER9B 3Q84A 4AZ6A 2OW7A 1ZYLA 1PS3A 2O0I1 3QNIA 4IW0A 4R5JA 1OAOA 4EZZA 2QKWA 2OW6A 5C5BA 4WPCA 2YL8A 4HR1A 3EJTA 3FD9A 2EFLA 1SUFA 5FLEX 1TQSA 3QNJA 3D50A 3D4ZA 3LMFA 3D2EA 3EJRA 3HAHA 4NPHA 1O7DC 2F7OA 4IWQA 3BVWA 4EZPA 1SU6A 3I04A 1DKZA 2OZNB 2X3XA 3I2WA 4AZIA 4IM2A 4IM0A 1U00A 3O3NB 4EZVA 3DX3A 3D52A 4JNEA 4EZUA 4B9QA 4UDXX 3DPQA 4EZRA 5FIGA 1I4DA 3T47A 2D4CA 1URUA 3B52X 5TKYA 3ERCC 2Z0VA 5C5BB 2ZXQA 2YLLA 3DDGA 3BUPA 4H6HA 3LLLA 2YL6A 1X04A 3RV1A 4EZSA 1GNLA 2RAJA 4EZWA 4JWEA 1R34A 2RT6A 3CV5A 3DX4A 2ND0A 3RPMA 4HYBA 2F7PA 3LVTA 2X3VA 2RAKA 2D1LA 1DKXA 2F18A 2F7QA 2EFKA 3C7NA 4AKVA 3SOGA 2YIBA 3QA8A 2YIVX 2WYHA 3HAJA 1TQTA 3CAZA 3CVRA 1HXKA 3I39X 3OK8A 3UITA 4EZTA 1ZWWA 3BVVA 3T48A 4FM3A 3DX2A 2WINM 4JL9A 2QXLA 3T46A 1I49A 3DX0A 1YWMA 2C08A 3DPPA 1WDZA 3EJUA 2KHOA 3VKHA 4I1QA 2Q12A 4AZHA 5KBPA 2F1BA 2Q13A 4AZ5A 3HAIA 1TQWA 4H6IA 2X3WA 2JNKA 1TQVA 2MI7A 2OO2A 2NCZA 2F1AA 2PY6A 3KDRA 4JN4A 2YIAA 1QWUA 4G6QA 3BUDA 4KIKA 4IWPA 3CKDA 3ABHA 3D51A 3F7WA 3RV0A 2RAIA 2ALWA 3M3WA 3GI7A 3BUQA 3KAWA 3Q0KA 2Z0NA 3BVXA 4JWIA 4NQIA 3D4YA 4BNEA 4E3CA 1W9MA 3DX1A 4D8JA 2GF4A 1E2UA 4EZXA 1UPXA 1JQKA 1Y2OA 1E1DA 3ER8C 2LXYA 4IWOA 4FZOA 2YLAA 4H8SA 3I01A 4AZ7A 4F00A 2ND1A 4M0MA 4R5KA 4HY9A 3EJPA 2Z8YA 3T4AG 2YL5A 1I4LA 4IM3A 2EX3B 1GN9A 3CZNA 3EJSA 3O3MB 2YI9A 2X5CA 4KIKB 1OA1A 1O7DB 2FYVA 1OA0A 1E9VA 4JNFA 1QWNA 2OBLA 3DPOA 3A98A 1QX1A 4ATMA 3KAVA 3D2FA 1I4TA 1X03A 3VEAA 4EZYA 1HTYA 4AZCB 3VEBA 4EZQA 1SU8A 4R5IA 2WYIA 4EZNA 2JNSA 4NSWA 3SYVA 2QFFA 3DYTA 1DKYA 2YL9A 2N3KA 3B51X
chains in the Genus database with same CATH topology
3QWEA 4I1QA 3HAJA 4H8SA 4BNEA 2Q12A 3G9GA 3CAZA 1I4DA 2FICA 2D4CA 3QNIA 4WPEA 1URUA 4DCNC 3ABHA 2Q13A 1I49A 2X3VA 2Z0OA 2RAKA 3ACOA 3PLTA 2RAIA 2X3XA 2Z0VA 3HAIA 3I2WA 3OK8A 2D1LA 3M3WA 3QE6A 4NSWA 5C5BB 3SYVA 4DYLA 2ELBA 4AVMA 2X3WA 4ATMA 4FZSA 2V0OA 5C5BA 3DYTA 4WPCA 1ZWWA 2C08A 2EFKA 2YKTA 1Y2OA 1I4LA 2Z0NA 3Q0KA 3Q84A 1I4TA 3LLLA 1X03A 1WDZA 1X04A 3HAHA 4NQIA 4AKVA 3SOGA 2EFLA 2RAJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QWE A;  4I1Q A;  3HAJ A;  4H8S A;  4BNE A;  2Q12 A;  3G9G A;  3CAZ A;  1I4D A;  2FIC A;  2D4C A;  3QNI A;  4WPE A;  1URU A;  4DCN C;  3ABH A;  2Q13 A;  1I49 A;  2X3V A;  2Z0O A;  2RAK A;  3ACO A;  3PLT A;  2RAI A;  2X3X A;  2Z0V A;  3HAI A;  3I2W A;  3OK8 A;  2D1L A;  3M3W A;  3QE6 A;  4NSW A;  5C5B B;  3SYV A;  4DYL A;  2ELB A;  4AVM A;  2X3W A;  4ATM A;  4FZS A;  2V0O A;  5C5B A;  3DYT A;  4WPC A;  1ZWW A;  2C08 A;  2EFK A;  2YKT A;  1Y2O A;  1I4L A;  2Z0N A;  3Q0K A;  3Q84 A;  1I4T A;  3LLL A;  1X03 A;  1WDZ A;  1X04 A;  3HAH A;  4NQI A;  4AKV A;  3SOG A;  2EFL A;  2RAJ A; 
#chains in the Genus database with same CATH topology
 3O3O B;  1HWW A;  2LM0 A;  4PO2 A;  3BUI A;  3L3P A;  2FIC A;  1GNT A;  4DCN C;  4F01 A;  2YI8 A;  1MJG A;  3BVU A;  1TQU A;  4AVM A;  3T49 A;  2YKT A;  3OWG A;  4R5L A;  4R5G A;  3L3O M;  3QWE A;  4EZO A;  2PMR A;  3EJQ A;  3OHX M;  1SU7 A;  3G9G A;  3BUB A;  4AZC A;  4JLC A;  3B53 X;  3BLB A;  2Z0O A;  3ACO A;  4HR1 B;  2ELB A;  4JWD A;  2V0O A;  4AZB A;  4AZG A;  1LQ7 A;  3CZS A;  3DDF A;  2EWF A;  4JWC A;  2GA9 D;  1R33 A;  1R5E A;  3ZED A;  4UDY X;  4WPE A;  2OBM A;  3PLT A;  5E84 A;  3QE6 A;  2GAF D;  4DYL A;  3BVT A;  4FZS A;  2F7R A;  4E81 A;  4FZP A;  3ER9 B;  3Q84 A;  4AZ6 A;  2OW7 A;  1ZYL A;  1PS3 A;  2O0I 1;  3QNI A;  4IW0 A;  4R5J A;  1OAO A;  4EZZ A;  2QKW A;  2OW6 A;  5C5B A;  4WPC A;  2YL8 A;  4HR1 A;  3EJT A;  3FD9 A;  2EFL A;  1SUF A;  5FLE X;  1TQS A;  3QNJ A;  3D50 A;  3D4Z A;  3LMF A;  3D2E A;  3EJR A;  3HAH A;  4NPH A;  1O7D C;  2F7O A;  4IWQ A;  3BVW A;  4EZP A;  1SU6 A;  3I04 A;  1DKZ A;  2OZN B;  2X3X A;  3I2W A;  4AZI A;  4IM2 A;  4IM0 A;  1U00 A;  3O3N B;  4EZV A;  3DX3 A;  3D52 A;  4JNE A;  4EZU A;  4B9Q A;  4UDX X;  3DPQ A;  4EZR A;  5FIG A;  1I4D A;  3T47 A;  2D4C A;  1URU A;  3B52 X;  5TKY A;  3ERC C;  2Z0V A;  5C5B B;  2ZXQ A;  2YLL A;  3DDG A;  3BUP A;  4H6H A;  3LLL A;  2YL6 A;  1X04 A;  3RV1 A;  4EZS A;  1GNL A;  2RAJ A;  4EZW A;  4JWE A;  1R34 A;  2RT6 A;  3CV5 A;  3DX4 A;  2ND0 A;  3RPM A;  4HYB A;  2F7P A;  3LVT A;  2X3V A;  2RAK A;  2D1L A;  1DKX A;  2F18 A;  2F7Q A;  2EFK A;  3C7N A;  4AKV A;  3SOG A;  2YIB A;  3QA8 A;  2YIV X;  2WYH A;  3HAJ A;  1TQT A;  3CAZ A;  3CVR A;  1HXK A;  3I39 X;  3OK8 A;  3UIT A;  4EZT A;  1ZWW A;  3BVV A;  3T48 A;  4FM3 A;  3DX2 A;  2WIN M;  4JL9 A;  2QXL A;  3T46 A;  1I49 A;  3DX0 A;  1YWM A;  2C08 A;  3DPP A;  1WDZ A;  3EJU A;  2KHO A;  3VKH A;  4I1Q A;  2Q12 A;  4AZH A;  5KBP A;  2F1B A;  2Q13 A;  4AZ5 A;  3HAI A;  1TQW A;  4H6I A;  2X3W A;  2JNK A;  1TQV A;  2MI7 A;  2OO2 A;  2NCZ A;  2F1A A;  2PY6 A;  3KDR A;  4JN4 A;  2YIA A;  1QWU A;  4G6Q A;  3BUD A;  4KIK A;  4IWP A;  3CKD A;  3ABH A;  3D51 A;  3F7W A;  3RV0 A;  2RAI A;  2ALW A;  3M3W A;  3GI7 A;  3BUQ A;  3KAW A;  3Q0K A;  2Z0N A;  3BVX A;  4JWI A;  4NQI A;  3D4Y A;  4BNE A;  4E3C A;  1W9M A;  3DX1 A;  4D8J A;  2GF4 A;  1E2U A;  4EZX A;  1UPX A;  1JQK A;  1Y2O A;  1E1D A;  3ER8 C;  2LXY A;  4IWO A;  4FZO A;  2YLA A;  4H8S A;  3I01 A;  4AZ7 A;  4F00 A;  2ND1 A;  4M0M A;  4R5K A;  4HY9 A;  3EJP A;  2Z8Y A;  3T4A G;  2YL5 A;  1I4L A;  4IM3 A;  2EX3 B;  1GN9 A;  3CZN A;  3EJS A;  3O3M B;  2YI9 A;  2X5C A;  4KIK B;  1OA1 A;  1O7D B;  2FYV A;  1OA0 A;  1E9V A;  4JNF A;  1QWN A;  2OBL A;  3DPO A;  3A98 A;  1QX1 A;  4ATM A;  3KAV A;  3D2F A;  1I4T A;  1X03 A;  3VEA A;  4EZY A;  1HTY A;  4AZC B;  3VEB A;  4EZQ A;  1SU8 A;  4R5I A;  2WYI A;  4EZN A;  2JNS A;  4NSW A;  3SYV A;  2QFF A;  3DYT A;  1DKY A;  2YL9 A;  2N3K A;  3B51 X; 
#chains in the Genus database with same CATH homology
 3QWE A;  4I1Q A;  3HAJ A;  4H8S A;  4BNE A;  2Q12 A;  3G9G A;  3CAZ A;  1I4D A;  2FIC A;  2D4C A;  3QNI A;  4WPE A;  1URU A;  4DCN C;  3ABH A;  2Q13 A;  1I49 A;  2X3V A;  2Z0O A;  2RAK A;  3ACO A;  3PLT A;  2RAI A;  2X3X A;  2Z0V A;  3HAI A;  3I2W A;  3OK8 A;  2D1L A;  3M3W A;  3QE6 A;  4NSW A;  5C5B B;  3SYV A;  4DYL A;  2ELB A;  4AVM A;  2X3W A;  4ATM A;  4FZS A;  2V0O A;  5C5B A;  3DYT A;  4WPC A;  1ZWW A;  2C08 A;  2EFK A;  2YKT A;  1Y2O A;  1I4L A;  2Z0N A;  3Q0K A;  3Q84 A;  1I4T A;  3LLL A;  1X03 A;  1WDZ A;  1X04 A;  3HAH A;  4NQI A;  4AKV A;  3SOG A;  2EFL A;  2RAJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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