3SYVA

Crystal structure of mpacsin 3 f-bar domain mutant
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
285
structure length
249
Chain Sequence
SFWEAGNYRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLADWARKWRGAVEKGPQYGTLEKAWHAFFTAAERLSELHLEVREKLHGPDSERVRTWQRGAFHRQVLGGFRESRAAEDGFRKAQKPWLKRLKEVEASKKSYHTARKDEKEAEKMKTQYEQTLAELNRYTPRYMEDMEQAFESCQAAERQRLLFFKDVLLTLHQHLDLSSSDKFHELHRDLQQSIEAASDEEDLRWWRSTHGPGMAQF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Rigidity of wedge loop in PACSIN 3 protein is a key factor in dictating diameters of tubules
pubmed doi rcsb
molecule tags Endocytosis
source organism Mus musculus
molecule keywords Protein kinase C and casein kinase II substrate protein 3
total genus 106
structure length 249
sequence length 285
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature
pdb deposition date 2011-07-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3syvA01
3QE6A 4WPEA 2ELBA 3PLTA 4WPCA 2Q12A 2C08A 3LLLA 1I4LA 1X03A 3QWEA 3QNIA 3OK8A 3HAHA 2RAKA 3CAZA 4NQIA 2Z0OA 5C5BA 2EFKA 4ATMA 4AVMA 3HAJA 3ABHA 1I49A 2FICA 3DYTA 2D1LA 1Y2OA 2Z0VA 2X3WA 4DCNC 3SYVA 3Q84A 1WDZA 3M3WA 2V0OA 1URUA 2Z0NA 3HAIA 4NSWA 4FZSA 5C5BB 2Q13A 2YKTA 4BNEA 4I1QA 1I4TA 2RAJA 3Q0KA 3G9GA 2EFLA 2X3VA 2X3XA 1X04A 3I2WA 2D4CA 1ZWWA 4H8SA 4AKVA 1I4DA 3ACOA 4DYLA 3SOGA 2RAIA
chains in the Genus database with same CATH superfamily
3QE6A 3BVWA 1GNLA 4JLCA 1DKXA 4HR1B 1GNTA 3B52X 4I1QA 2OO2A 4E3CA 3ACOA 4EZZA 3KDRA 4HR1A 4IWQA 1SU8A 2Q12A 3RV1A 4IWPA 5E84A 3BLBA 2FICA 2YL9A 1R33A 2YI8A 4R5LA 4FZPA 1I4TA 4EZRA 2X3VA 1UPXA 3DDGA 1HXKA 3PLTA 2FYVA 4R5JA 3C7NA 1TQWA 1MJGA 4KIKB 4NSWA 3DX1A 4FZSA 2EFLA 2GA9D 1ZWWA 4EZTA 3D2FA 3RPMA 2ELBA 4KIKA 3CVRA 4D8JA 3T49A 4JWEA 3DX0A 3QNJA 3DDFA 3LVTA 2D1LA 3F7WA 2LM0A 3CKDA 2O0I1 4G6QA 2OBLA 1U00A 4IWOA 4WPCA 4IM0A 4E81A 3OK8A 4EZXA 4AZ7A 2F7QA 1TQTA 1QWNA 1WDZA 3M3WA 3UITA 4EZUA 3GI7A 1HWWA 1R5EA 3HAHA 5FLEX 3ERCC 1DKZA 2ND1A 2KHOA 1W9MA 4H6IA 3BUQA 4AZHA 3RV0A 2F7PA 5KBPA 2F7RA 2X3XA 3I2WA 3VEAA 2C08A 1I4LA 3QNIA 2F1AA 1R34A 3D2EA 3BVTA 1OA1A 4M0MA 4DCNC 3B51X 3Q84A 2WYHA 2Z8YA 3A98A 3I39X 2D4CA 1E9VA 1O7DB 3EJUA 3EJPA 3QWEA 3CZSA 4JNFA 2EX3B 4R5GA 3ZEDA 2YL8A 3BVXA 1ZYLA 4EZQA 3I01A 2LXYA 3BUDA 2OZNB 3BUIA 2F1BA 3EJQA 4EZOA 3I04A 1I4DA 2OBMA 4WPEA 4FZOA 4FM3A 2JNSA 2Z0OA 3CZNA 3D50A 1I49A 4R5KA 1Y2OA 3DPOA 3FD9A 2ND0A 2V0OA 1URUA 2Z0NA 2YKTA 3D4YA 1PS3A 3Q0KA 2OW6A 3D51A 3DX3A 3T46A 3CV5A 2MI7A 2RT6A 4JNEA 3T48A 3KAVA 2QFFA 3DX4A 2WYIA 4NQIA 3BVVA 3QA8A 2X5CA 2QKWA 3HAJA 1JQKA 2Z0VA 4UDYX 3ER8C 4AZBA 3BUBA 2NCZA 3T4AG 1LQ7A 4EZNA 3EJTA 4HY9A 3LLLA 2PMRA 3CAZA 1SUFA 4IM3A 3DPPA 1O7DC 4JL9A 3ABHA 1QWUA 2YLLA 4PO2A 4F00A 2GF4A 5TKYA 1X04A 1OA0A 4IW0A 4AZ5A 2PY6A 4F01A 2EWFA 2YL5A 4EZWA 2ZXQA 2YI9A 4R5IA 3O3OB 2GAFD 3VEBA 5C5BB 1GN9A 4H6HA 4HYBA 4DYLA 4AZCB 1TQVA 4JWIA 3O3NB 2WINM 4UDXX 5C5BA 3OHXM 4AZ6A 1HTYA 4EZSA 3BUPA 4AZCA 2F7OA 2YLAA 4JWDA 1SU7A 2Q13A 2YL6A 5FIGA 4AZGA 1X03A 4B9QA 2EFKA 4ATMA 4AVMA 4EZYA 4NPHA 4JN4A 3HAIA 3DPQA 2JNKA 2YIBA 3LMFA 1E1DA 2RAJA 3G9GA 3D4ZA 2YIAA 3BVUA 4H8SA 3L3PA 3SOGA 3VKHA 1TQSA 1SU6A 1TQUA 3T47A 2OW7A 3EJRA 3L3OM 3DYTA 1OAOA 3B53X 2RAIA 1QX1A 2F18A 4IM2A 2ALWA 2RAKA 3OWGA 3ER9B 3O3MB 1YWMA 2X3WA 4AZIA 3DX2A 3SYVA 4EZPA 3EJSA 4BNEA 2N3KA 3D52A 4EZVA 2YIVX 4JWCA 1E2UA 2QXLA 4AKVA 3KAWA 1DKYA
chains in the Genus database with same CATH topology
3QE6A 4WPEA 2ELBA 3PLTA 4WPCA 2Q12A 2C08A 3LLLA 1I4LA 1X03A 3QWEA 3QNIA 3OK8A 3HAHA 2RAKA 3CAZA 4NQIA 2Z0OA 5C5BA 2EFKA 4ATMA 4AVMA 3HAJA 3ABHA 1I49A 2FICA 3DYTA 2D1LA 1Y2OA 2Z0VA 2X3WA 4DCNC 3SYVA 3Q84A 1WDZA 3M3WA 2V0OA 1URUA 2Z0NA 3HAIA 4NSWA 4FZSA 5C5BB 2Q13A 2YKTA 4BNEA 4I1QA 1I4TA 2RAJA 3Q0KA 3G9GA 2EFLA 2X3VA 2X3XA 1X04A 3I2WA 2D4CA 1ZWWA 4H8SA 4AKVA 1I4DA 3ACOA 4DYLA 3SOGA 2RAIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QE6 A;  4WPE A;  2ELB A;  3PLT A;  4WPC A;  2Q12 A;  2C08 A;  3LLL A;  1I4L A;  1X03 A;  3QWE A;  3QNI A;  3OK8 A;  3HAH A;  2RAK A;  3CAZ A;  4NQI A;  2Z0O A;  5C5B A;  2EFK A;  4ATM A;  4AVM A;  3HAJ A;  3ABH A;  1I49 A;  2FIC A;  3DYT A;  2D1L A;  1Y2O A;  2Z0V A;  2X3W A;  4DCN C;  3SYV A;  3Q84 A;  1WDZ A;  3M3W A;  2V0O A;  1URU A;  2Z0N A;  3HAI A;  4NSW A;  4FZS A;  5C5B B;  2Q13 A;  2YKT A;  4BNE A;  4I1Q A;  1I4T A;  2RAJ A;  3Q0K A;  3G9G A;  2EFL A;  2X3V A;  2X3X A;  1X04 A;  3I2W A;  2D4C A;  1ZWW A;  4H8S A;  4AKV A;  1I4D A;  3ACO A;  4DYL A;  3SOG A;  2RAI A; 
#chains in the Genus database with same CATH topology
 3QE6 A;  3BVW A;  1GNL A;  4JLC A;  1DKX A;  4HR1 B;  1GNT A;  3B52 X;  4I1Q A;  2OO2 A;  4E3C A;  3ACO A;  4EZZ A;  3KDR A;  4HR1 A;  4IWQ A;  1SU8 A;  2Q12 A;  3RV1 A;  4IWP A;  5E84 A;  3BLB A;  2FIC A;  2YL9 A;  1R33 A;  2YI8 A;  4R5L A;  4FZP A;  1I4T A;  4EZR A;  2X3V A;  1UPX A;  3DDG A;  1HXK A;  3PLT A;  2FYV A;  4R5J A;  3C7N A;  1TQW A;  1MJG A;  4KIK B;  4NSW A;  3DX1 A;  4FZS A;  2EFL A;  2GA9 D;  1ZWW A;  4EZT A;  3D2F A;  3RPM A;  2ELB A;  4KIK A;  3CVR A;  4D8J A;  3T49 A;  4JWE A;  3DX0 A;  3QNJ A;  3DDF A;  3LVT A;  2D1L A;  3F7W A;  2LM0 A;  3CKD A;  2O0I 1;  4G6Q A;  2OBL A;  1U00 A;  4IWO A;  4WPC A;  4IM0 A;  4E81 A;  3OK8 A;  4EZX A;  4AZ7 A;  2F7Q A;  1TQT A;  1QWN A;  1WDZ A;  3M3W A;  3UIT A;  4EZU A;  3GI7 A;  1HWW A;  1R5E A;  3HAH A;  5FLE X;  3ERC C;  1DKZ A;  2ND1 A;  2KHO A;  1W9M A;  4H6I A;  3BUQ A;  4AZH A;  3RV0 A;  2F7P A;  5KBP A;  2F7R A;  2X3X A;  3I2W A;  3VEA A;  2C08 A;  1I4L A;  3QNI A;  2F1A A;  1R34 A;  3D2E A;  3BVT A;  1OA1 A;  4M0M A;  4DCN C;  3B51 X;  3Q84 A;  2WYH A;  2Z8Y A;  3A98 A;  3I39 X;  2D4C A;  1E9V A;  1O7D B;  3EJU A;  3EJP A;  3QWE A;  3CZS A;  4JNF A;  2EX3 B;  4R5G A;  3ZED A;  2YL8 A;  3BVX A;  1ZYL A;  4EZQ A;  3I01 A;  2LXY A;  3BUD A;  2OZN B;  3BUI A;  2F1B A;  3EJQ A;  4EZO A;  3I04 A;  1I4D A;  2OBM A;  4WPE A;  4FZO A;  4FM3 A;  2JNS A;  2Z0O A;  3CZN A;  3D50 A;  1I49 A;  4R5K A;  1Y2O A;  3DPO A;  3FD9 A;  2ND0 A;  2V0O A;  1URU A;  2Z0N A;  2YKT A;  3D4Y A;  1PS3 A;  3Q0K A;  2OW6 A;  3D51 A;  3DX3 A;  3T46 A;  3CV5 A;  2MI7 A;  2RT6 A;  4JNE A;  3T48 A;  3KAV A;  2QFF A;  3DX4 A;  2WYI A;  4NQI A;  3BVV A;  3QA8 A;  2X5C A;  2QKW A;  3HAJ A;  1JQK A;  2Z0V A;  4UDY X;  3ER8 C;  4AZB A;  3BUB A;  2NCZ A;  3T4A G;  1LQ7 A;  4EZN A;  3EJT A;  4HY9 A;  3LLL A;  2PMR A;  3CAZ A;  1SUF A;  4IM3 A;  3DPP A;  1O7D C;  4JL9 A;  3ABH A;  1QWU A;  2YLL A;  4PO2 A;  4F00 A;  2GF4 A;  5TKY A;  1X04 A;  1OA0 A;  4IW0 A;  4AZ5 A;  2PY6 A;  4F01 A;  2EWF A;  2YL5 A;  4EZW A;  2ZXQ A;  2YI9 A;  4R5I A;  3O3O B;  2GAF D;  3VEB A;  5C5B B;  1GN9 A;  4H6H A;  4HYB A;  4DYL A;  4AZC B;  1TQV A;  4JWI A;  3O3N B;  2WIN M;  4UDX X;  5C5B A;  3OHX M;  4AZ6 A;  1HTY A;  4EZS A;  3BUP A;  4AZC A;  2F7O A;  2YLA A;  4JWD A;  1SU7 A;  2Q13 A;  2YL6 A;  5FIG A;  4AZG A;  1X03 A;  4B9Q A;  2EFK A;  4ATM A;  4AVM A;  4EZY A;  4NPH A;  4JN4 A;  3HAI A;  3DPQ A;  2JNK A;  2YIB A;  3LMF A;  1E1D A;  2RAJ A;  3G9G A;  3D4Z A;  2YIA A;  3BVU A;  4H8S A;  3L3P A;  3SOG A;  3VKH A;  1TQS A;  1SU6 A;  1TQU A;  3T47 A;  2OW7 A;  3EJR A;  3L3O M;  3DYT A;  1OAO A;  3B53 X;  2RAI A;  1QX1 A;  2F18 A;  4IM2 A;  2ALW A;  2RAK A;  3OWG A;  3ER9 B;  3O3M B;  1YWM A;  2X3W A;  4AZI A;  3DX2 A;  3SYV A;  4EZP A;  3EJS A;  4BNE A;  2N3K A;  3D52 A;  4EZV A;  2YIV X;  4JWC A;  1E2U A;  2QXL A;  4AKV A;  3KAW A;  1DKY A; 
#chains in the Genus database with same CATH homology
 3QE6 A;  4WPE A;  2ELB A;  3PLT A;  4WPC A;  2Q12 A;  2C08 A;  3LLL A;  1I4L A;  1X03 A;  3QWE A;  3QNI A;  3OK8 A;  3HAH A;  2RAK A;  3CAZ A;  4NQI A;  2Z0O A;  5C5B A;  2EFK A;  4ATM A;  4AVM A;  3HAJ A;  3ABH A;  1I49 A;  2FIC A;  3DYT A;  2D1L A;  1Y2O A;  2Z0V A;  2X3W A;  4DCN C;  3SYV A;  3Q84 A;  1WDZ A;  3M3W A;  2V0O A;  1URU A;  2Z0N A;  3HAI A;  4NSW A;  4FZS A;  5C5B B;  2Q13 A;  2YKT A;  4BNE A;  4I1Q A;  1I4T A;  2RAJ A;  3Q0K A;  3G9G A;  2EFL A;  2X3V A;  2X3X A;  1X04 A;  3I2W A;  2D4C A;  1ZWW A;  4H8S A;  4AKV A;  1I4D A;  3ACO A;  4DYL A;  3SOG A;  2RAI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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