3VYGB

Crystal structure of thiocyanate hydrolase mutant r136w
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
152
structure length
152
Chain Sequence
SSIREEVHRHLGTVALMQPALHQQTHAPAPTEITHTLFRAYTRVPHDVGGEADVPIEYHEKEEEIWELNTFATCECLAWRGVWTAEERRRKQNCDVGQTVYLGMPYYGRWLLTAARILVDKQFVTLTELHNKIVEMRERVASGQGLGEYLPP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Thiobacillus thioparus
publication title Effects of argnine residue around the substrate pocket on the substrate specificity of thiocyanate hydrolase
rcsb
molecule keywords Thiocyanate hydrolase subunit alpha
total genus 42
structure length 152
sequence length 152
chains with identical sequence E, H, K
ec nomenclature ec 3.5.5.8: Thiocyanate hydrolase.
pdb deposition date 2012-09-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02211 NHase_beta Nitrile hydratase beta subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.472.20 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin A; domain 1 3vygB00
2ZPIB 1UGQB 2CZ0B 1AHJB 1IREB 2AHJB 2ZPBB 2CZ7B 2ZPEB 3A8OB 3QYGB 4OB1B 3VYHB 4FM4B 3X28B 2DD5B 3QXEB 4OB2B 2ZPGB 3X24B 4ZGJB 3X20B 3QZ5B 4ZGDB 2ZPFB 1UGRB 2DPPB 3A8LB 3QZ9B 3VYGB 4ZGEB 1V29B 2CZ6B 3HHTB 3WVEB 2DD4B 3A8HB 1UGSB 2DXBB 2DXCB 3A8MB 3A8GB 1UGPB 2QDYB 4OB3B 3X25B 3WVDB 4OB0B 2CYZB 3QYHB 3X26B 2ZPHB 2ZCFB 2ZZDB 2D0QB 2CZ1B
chains in the Genus database with same CATH superfamily
4HLQA 4TTHA 4CXAB 3X24B 3PO3S 5CYIB 1XO2A 3EIDB 4ZGDB 3A8LB 2QQ8A 5HBEB 4F7SB 2X1NB 3BHUB 4BCMD 4F7NB 2ZCFB 2C5VB 3DJBA 2ZZDB 4HNVA 5IDPB 3WVDB 3QYGB 3DL1A 3DTOA 3QXEB 4ZGJB 3GTMS 2KMGA 4BCGB 4F6SB 2CCIB 1VINA 3G33B 4BY1X 3A8GB 1FKMA 5BNJB 2QDYB 5L2WB 3LQ5B 4BCND 4I3ZB 5I5ZB 1AHJB 4AKHA 3BG9A 2IW8B 2BS2A 4M6VA 1E7PA 5LQFB 1V29B 2UZBB 3BLHB 3QYBA 4ELJA 3TNWB 2WIPB 5ICPB 3HB9A 3DDQB 3NDQA 1H1PB 2EUFA 3HZJA 4OB2B 4OGRB 4CFWB 3HO8A 1OL1B 4CFMB 2C4GB 2ZPFB 2V22B 2PK9B 3KHIA 2DD4B 1H28B 3A8HB 4LOCA 1H24B 1JKWA 2WEVB 1QLBA 3A8OB 3X28B 2ZPEB 4EOPB 1F5QB 1AISB 2C5XB 4OR5B 1GY3B 2UUEB 4UN0A 5DQWA 2W9FA 4BCIB 2WMBB 4FX3B 4BXXX 1PKDB 5HNBB 3BHTB 2PMIB 4CFXB 1OI9B 4NC6A 4BCKB 2WHBB 2IW6B 1IREB 1OIYB 5IDNB 2I40B 5LMKB 3K7AM 2PHGA 2BS4A 4CRLB 3TW6A 1D3UB 2WJ9A 4MFDA 3VKHA 4MIMA 2I53A 5ACBA 3A8MB 3X25B 2BKZB 4CFNB 4CFUD 2QDJA 4YOSA 1URCB 2AHJB 2CZ7B 4YC3B 2F2CA 2PJQA 2WMAB 3MY1B 2IN3A 4F6UB 1ENWA 3TN8B 2CZ6B 2C5OB 4BCHB 1ZP2A 2WFYB 1UNHD 4CFVB 2G9XB 2JGZB 4BCJB 1H27B 1H25B 2R7GA 2ZPIB 1VOLA 2CZ0B 3M03A 3O0GD 1H1SB 4Z6YA 1OKWB 4HNTA 4BCPB 3QWLA 4BCNB 4BY7X 4NSTB 2PK2A 4EOSB 4BCOB 2WPAB 4EOIB 5CEIB 4II5B 1TD6A 1OL2B 4BBSM 2ZPBB 3F5XB 3B57A 3QZ9B 3QYEA 1GH6B 1UGSB 2BS3A 1H1QB 2QGSA 1VYWB 5HBJB 1UGQB 3BG5A 4EC9B 2KR6A 5FGKB 4EONB 1AD6A 4ZGEB 4ROEA 1QMZB 3EOCB 3DDPB 4F6WB 1JSTB 3TW7A 3EJ1B 4FM4B 3BG3A 4YOOA 2C6TB 2QF7A 3X20B 4EOJB 3RGFB 1UGRB 4BCQD 2DXBB 4HNUA 2QFZA 2LW4A 1W98B 4RODA 4OB3B 1H4LD 4ROCA 1O9KA 2ZPGB 4EOKB 4YOZA 4BBRM 4JX5A 4CFUB 4BCMB 3WVEB 1P5EB 2B9RA 3MI9B 3QHRB 1JOWA 2W2HA 2CYZB 4JX6A 5HBHB 4KRDB 4JX4A 3TNIB 1O9KB 3MY5B 4AI6A 4G6LB 4IMYB 4F7JB 4EOMB 2DPPB 3H4CA 4F7LB 4HL4A 1BU2A 4AKGA 1UGPB 1UNLD 1C9BA 1GUXA 2ZPHB 3TNHB 2CZ1B 1G3NC 3VYHB 4OB1B 4BCFB 2UZEB 4KRCB 4AKIA 3BHVB 3VYGB 2W9ZA 2W96A 4EOQB 1UNGD 1FVVB 5HVYB 5EJCA 5IHYA 2UZLB 2WIHB 4OB0B 1GUXB 4EORB 1FINB 2IW9B 3QYHB 1E9HB 1KXUA 1JSUB 5EFQB 4QSHA 2DD5B 2C5NB 4F70B 1H26B 2BPMB 2G77A 2DXCB 4EC8B 2DMEA 2CCHB 4EOLB 2IVXA 2CJMB 2UZDB 3QHWB 1N4MA 1OIUB 3VKGA 2WXVB 2D0QB 5DQVA 5IF1B 4ELLA 3POMA 3DOGB 1TFBA 1OGUB 3QZ5B 1OKVB 3HBLA 3MIAB 4MFEA 3HHTB 1H1RB 5HQ0B 3BLQB 3BLRB 3X26B 4Y72B 4EOOB 2W99A 4BCQB
chains in the Genus database with same CATH topology
4HLQA 4BBSM 2ZPBB 4AI6A 3X24B 3A8OB 3X28B 2ZPEB 4ZGDB 2DPPB 3A8LB 2QQ8A 3H4CA 3QZ9B 3QYEA 1UGSB 2BS3A 4HL4A 4AKGA 1UGPB 2ZPHB 2ZCFB 4NC6A 2ZZDB 4HNVA 2CZ1B 1UGQB 1IREB 3VYHB 3WVDB 3BG5A 3QYGB 4OB1B 3DL1A 3QXEB 2KR6A 4ZGJB 4AKIA 2KMGA 2BS4A 3VYGB 3TW6A 4ZGEB 2WJ9A 4MFDA 3VKHA 4MIMA 5EJCA 3A8MB 3A8GB 1FKMA 2QDYB 3X25B 4OB0B 3QYHB 2QDJA 3TW7A 1AHJB 2AHJB 2CZ7B 4FM4B 4AKHA 3BG3A 4QSHA 2DD5B 3BG9A 2BS2A 4M6VA 2QF7A 3X20B 1E7PA 1UGRB 1V29B 2CZ6B 2G77A 3QYBA 2DXCB 2DXBB 4HNUA 2QFZA 4ELJA 3HB9A 4OB3B 3VKGA 2D0QB 2ZPGB 2ZPIB 3HZJA 4OB2B 2CZ0B 3HO8A 4Z6YA 4BBRM 4HNTA 3QZ5B 3QWLA 3HBLA 2ZPFB 4JX5A 3KHIA 4MFEA 3HHTB 3WVEB 2DD4B 3A8HB 4LOCA 2CYZB 4JX6A 3X26B 4JX4A 1QLBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZPI B;  1UGQ B;  2CZ0 B;  1AHJ B;  1IRE B;  2AHJ B;  2ZPB B;  2CZ7 B;  2ZPE B;  3A8O B;  3QYG B;  4OB1 B;  3VYH B;  4FM4 B;  3X28 B;  2DD5 B;  3QXE B;  4OB2 B;  2ZPG B;  3X24 B;  4ZGJ B;  3X20 B;  3QZ5 B;  4ZGD B;  2ZPF B;  1UGR B;  2DPP B;  3A8L B;  3QZ9 B;  3VYG B;  4ZGE B;  1V29 B;  2CZ6 B;  3HHT B;  3WVE B;  2DD4 B;  3A8H B;  1UGS B;  2DXB B;  2DXC B;  3A8M B;  3A8G B;  1UGP B;  2QDY B;  4OB3 B;  3X25 B;  3WVD B;  4OB0 B;  2CYZ B;  3QYH B;  3X26 B;  2ZPH B;  2ZCF B;  2ZZD B;  2D0Q B;  2CZ1 B; 
#chains in the Genus database with same CATH topology
 4HLQ A;  4TTH A;  4CXA B;  3X24 B;  3PO3 S;  5CYI B;  1XO2 A;  3EID B;  4ZGD B;  3A8L B;  2QQ8 A;  5HBE B;  4F7S B;  2X1N B;  3BHU B;  4BCM D;  4F7N B;  2ZCF B;  2C5V B;  3DJB A;  2ZZD B;  4HNV A;  5IDP B;  3WVD B;  3QYG B;  3DL1 A;  3DTO A;  3QXE B;  4ZGJ B;  3GTM S;  2KMG A;  4BCG B;  4F6S B;  2CCI B;  1VIN A;  3G33 B;  4BY1 X;  3A8G B;  1FKM A;  5BNJ B;  2QDY B;  5L2W B;  3LQ5 B;  4BCN D;  4I3Z B;  5I5Z B;  1AHJ B;  4AKH A;  3BG9 A;  2IW8 B;  2BS2 A;  4M6V A;  1E7P A;  5LQF B;  1V29 B;  2UZB B;  3BLH B;  3QYB A;  4ELJ A;  3TNW B;  2WIP B;  5ICP B;  3HB9 A;  3DDQ B;  3NDQ A;  1H1P B;  2EUF A;  3HZJ A;  4OB2 B;  4OGR B;  4CFW B;  3HO8 A;  1OL1 B;  4CFM B;  2C4G B;  2ZPF B;  2V22 B;  2PK9 B;  3KHI A;  2DD4 B;  1H28 B;  3A8H B;  4LOC A;  1H24 B;  1JKW A;  2WEV B;  1QLB A;  3A8O B;  3X28 B;  2ZPE B;  4EOP B;  1F5Q B;  1AIS B;  2C5X B;  4OR5 B;  1GY3 B;  2UUE B;  4UN0 A;  5DQW A;  2W9F A;  4BCI B;  2WMB B;  4FX3 B;  4BXX X;  1PKD B;  5HNB B;  3BHT B;  2PMI B;  4CFX B;  1OI9 B;  4NC6 A;  4BCK B;  2WHB B;  2IW6 B;  1IRE B;  1OIY B;  5IDN B;  2I40 B;  5LMK B;  3K7A M;  2PHG A;  2BS4 A;  4CRL B;  3TW6 A;  1D3U B;  2WJ9 A;  4MFD A;  3VKH A;  4MIM A;  2I53 A;  5ACB A;  3A8M B;  3X25 B;  2BKZ B;  4CFN B;  4CFU D;  2QDJ A;  4YOS A;  1URC B;  2AHJ B;  2CZ7 B;  4YC3 B;  2F2C A;  2PJQ A;  2WMA B;  3MY1 B;  2IN3 A;  4F6U B;  1ENW A;  3TN8 B;  2CZ6 B;  2C5O B;  4BCH B;  1ZP2 A;  2WFY B;  1UNH D;  4CFV B;  2G9X B;  2JGZ B;  4BCJ B;  1H27 B;  1H25 B;  2R7G A;  2ZPI B;  1VOL A;  2CZ0 B;  3M03 A;  3O0G D;  1H1S B;  4Z6Y A;  1OKW B;  4HNT A;  4BCP B;  3QWL A;  4BCN B;  4BY7 X;  4NST B;  2PK2 A;  4EOS B;  4BCO B;  2WPA B;  4EOI B;  5CEI B;  4II5 B;  1TD6 A;  1OL2 B;  4BBS M;  2ZPB B;  3F5X B;  3B57 A;  3QZ9 B;  3QYE A;  1GH6 B;  1UGS B;  2BS3 A;  1H1Q B;  2QGS A;  1VYW B;  5HBJ B;  1UGQ B;  3BG5 A;  4EC9 B;  2KR6 A;  5FGK B;  4EON B;  1AD6 A;  4ZGE B;  4ROE A;  1QMZ B;  3EOC B;  3DDP B;  4F6W B;  1JST B;  3TW7 A;  3EJ1 B;  4FM4 B;  3BG3 A;  4YOO A;  2C6T B;  2QF7 A;  3X20 B;  4EOJ B;  3RGF B;  1UGR B;  4BCQ D;  2DXB B;  4HNU A;  2QFZ A;  2LW4 A;  1W98 B;  4ROD A;  4OB3 B;  1H4L D;  4ROC A;  1O9K A;  2ZPG B;  4EOK B;  4YOZ A;  4BBR M;  4JX5 A;  4CFU B;  4BCM B;  3WVE B;  1P5E B;  2B9R A;  3MI9 B;  3QHR B;  1JOW A;  2W2H A;  2CYZ B;  4JX6 A;  5HBH B;  4KRD B;  4JX4 A;  3TNI B;  1O9K B;  3MY5 B;  4AI6 A;  4G6L B;  4IMY B;  4F7J B;  4EOM B;  2DPP B;  3H4C A;  4F7L B;  4HL4 A;  1BU2 A;  4AKG A;  1UGP B;  1UNL D;  1C9B A;  1GUX A;  2ZPH B;  3TNH B;  2CZ1 B;  1G3N C;  3VYH B;  4OB1 B;  4BCF B;  2UZE B;  4KRC B;  4AKI A;  3BHV B;  3VYG B;  2W9Z A;  2W96 A;  4EOQ B;  1UNG D;  1FVV B;  5HVY B;  5EJC A;  5IHY A;  2UZL B;  2WIH B;  4OB0 B;  1GUX B;  4EOR B;  1FIN B;  2IW9 B;  3QYH B;  1E9H B;  1KXU A;  1JSU B;  5EFQ B;  4QSH A;  2DD5 B;  2C5N B;  4F70 B;  1H26 B;  2BPM B;  2G77 A;  2DXC B;  4EC8 B;  2DME A;  2CCH B;  4EOL B;  2IVX A;  2CJM B;  2UZD B;  3QHW B;  1N4M A;  1OIU B;  3VKG A;  2WXV B;  2D0Q B;  5DQV A;  5IF1 B;  4ELL A;  3POM A;  3DOG B;  1TFB A;  1OGU B;  3QZ5 B;  1OKV B;  3HBL A;  3MIA B;  4MFE A;  3HHT B;  1H1R B;  5HQ0 B;  3BLQ B;  3BLR B;  3X26 B;  4Y72 B;  4EOO B;  2W99 A;  4BCQ B; 
#chains in the Genus database with same CATH homology
 4HLQ A;  4BBS M;  2ZPB B;  4AI6 A;  3X24 B;  3A8O B;  3X28 B;  2ZPE B;  4ZGD B;  2DPP B;  3A8L B;  2QQ8 A;  3H4C A;  3QZ9 B;  3QYE A;  1UGS B;  2BS3 A;  4HL4 A;  4AKG A;  1UGP B;  2ZPH B;  2ZCF B;  4NC6 A;  2ZZD B;  4HNV A;  2CZ1 B;  1UGQ B;  1IRE B;  3VYH B;  3WVD B;  3BG5 A;  3QYG B;  4OB1 B;  3DL1 A;  3QXE B;  2KR6 A;  4ZGJ B;  4AKI A;  2KMG A;  2BS4 A;  3VYG B;  3TW6 A;  4ZGE B;  2WJ9 A;  4MFD A;  3VKH A;  4MIM A;  5EJC A;  3A8M B;  3A8G B;  1FKM A;  2QDY B;  3X25 B;  4OB0 B;  3QYH B;  2QDJ A;  3TW7 A;  1AHJ B;  2AHJ B;  2CZ7 B;  4FM4 B;  4AKH A;  3BG3 A;  4QSH A;  2DD5 B;  3BG9 A;  2BS2 A;  4M6V A;  2QF7 A;  3X20 B;  1E7P A;  1UGR B;  1V29 B;  2CZ6 B;  2G77 A;  3QYB A;  2DXC B;  2DXB B;  4HNU A;  2QFZ A;  4ELJ A;  3HB9 A;  4OB3 B;  3VKG A;  2D0Q B;  2ZPG B;  2ZPI B;  3HZJ A;  4OB2 B;  2CZ0 B;  3HO8 A;  4Z6Y A;  4BBR M;  4HNT A;  3QZ5 B;  3QWL A;  3HBL A;  2ZPF B;  4JX5 A;  3KHI A;  4MFE A;  3HHT B;  3WVE B;  2DD4 B;  3A8H B;  4LOC A;  2CYZ B;  4JX6 A;  3X26 B;  4JX4 A;  1QLB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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