3VYGB

Crystal structure of thiocyanate hydrolase mutant r136w
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
152
structure length
152
Chain Sequence
SSIREEVHRHLGTVALMQPALHQQTHAPAPTEITHTLFRAYTRVPHDVGGEADVPIEYHEKEEEIWELNTFATCECLAWRGVWTAEERRRKQNCDVGQTVYLGMPYYGRWLLTAARILVDKQFVTLTELHNKIVEMRERVASGQGLGEYLPP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Effects of argnine residue around the substrate pocket on the substrate specificity of thiocyanate hydrolase
rcsb
molecule tags Hydrolase
source organism Thiobacillus thioparus
molecule keywords Thiocyanate hydrolase subunit alpha
total genus 42
structure length 152
sequence length 152
chains with identical sequence E, H, K
ec nomenclature ec 3.5.5.8: Thiocyanate hydrolase.
pdb deposition date 2012-09-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02211 NHase_beta Nitrile hydratase beta subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.472.20 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin A; domain 1 3vygB00
3QZ9B 2CZ0B 4ZGDB 1UGPB 3A8MB 4ZGEB 2ZPGB 1UGQB 3VYHB 3A8LB 3X26B 3A8OB 2DD4B 4FM4B 3QYHB 3VYGB 1IREB 2ZPEB 3A8HB 3HHTB 1V29B 2ZCFB 2DXBB 3QYGB 2CZ1B 2D0QB 2CZ6B 1UGRB 2ZPBB 3X24B 4OB1B 2ZPHB 4OB3B 4ZGJB 2ZPFB 3QZ5B 3WVEB 2ZZDB 2QDYB 2DXCB 2AHJB 1UGSB 2DD5B 3A8GB 3QXEB 2ZPIB 1AHJB 2CYZB 2DPPB 4OB0B 4OB2B 3X25B 2CZ7B 3X28B 3WVDB 3X20B
chains in the Genus database with same CATH superfamily
4F6SB 1JSTB 4ELJA 1JKWA 2KMGA 3MI9B 3DOGB 2ZPBB 1OL1B 2ZPFB 3TNIB 1H28B 4YOZA 2X1NB 4EC9B 3A8MB 2UZDB 3POMA 4AKIA 5DQWA 2W9FA 3K7AM 2AHJB 2PMIB 4AKGA 3TW7A 2DPPB 2CZ7B 3TNHB 3QZ9B 5HVYB 1OIUB 4LOCA 3A8LB 4EOQB 1GY3B 2BPMB 2C5OB 3VKGA 4FM4B 3QYHB 1OGUB 4EOPB 4G6LB 1PKDB 3TN8B 2QGSA 4QSHA 2CZ1B 2B9RA 1H1RB 2W99A 1O9KA 2ZZDB 3HB9A 4BCIB 3O0GD 1H24B 1H1SB 3X25B 1AISB 2C4GB 2I40B 4KRCB 4EOOB 4YC3B 3BHTB 1D3UB 1FKMA 5EJCA 4JX4A 4EC8B 2WMBB 3BG9A 5ICPB 2DD5B 4EORB 3EJ1B 4OB0B 4EOSB 4CRLB 1VYWB 3X20B 3DL1A 4BCND 1OI9B 3BLHB 2C5NB 2DD4B 4BCMD 4ROEA 2PJQA 2CCHB 4BCNB 3DDQB 1G3NC 4F7NB 2I53A 1FVVB 4BXXX 1GUXB 1H27B 4EOKB 4ZGJB 5HNBB 4JX6A 1E9HB 3BG5A 4NC6A 2CYZB 2WFYB 4RODA 2PHGA 1UGPB 4BY7X 2ZPGB 2BKZB 4II5B 4EONB 4UN0A 5HBEB 4CFNB 2IW8B 4AI6A 1UGRB 4HLQA 1OL2B 1UNLD 2UZLB 5HBHB 2C6TB 1C9BA 1FINB 3X28B 2BS2A 3KHIA 4BCPB 2G9XB 2WIPB 3HBLA 1VINA 1KXUA 4JX5A 2CCIB 3BHVB 5BNJB 4CXAB 2WXVB 3PO3S 3BLQB 2IVXA 3QZ5B 5IDNB 2C5VB 5IHYA 5I5ZB 4EOJB 2IN3A 2QDJA 1H1PB 5HBJB 4KRDB 3MY5B 1BU2A 1OIYB 1H1QB 4CFMB 1TD6A 4BCHB 1GUXA 3LQ5B 4TTHA 3DTOA 3EIDB 3DJBA 3VKHA 3WVDB 3MY1B 3NDQA 4BBSM 2BS3A 1ENWA 1UGQB 4MIMA 4YOOA 3A8OB 2IW9B 2PK9B 2QQ8A 4F7JB 4YOSA 1QMZB 2DXCB 3QHRB 4F70B 1AD6A 2WIHB 3DDPB 3BLRB 4ZGDB 4NSTB 3GTMS 5DQVA 3TW6A 5FGKB 3HHTB 2IW6B 4BCOB 3QYEA 1OKWB 4OB3B 1P5EB 3QYBA 4BCMB 4I3ZB 4CFUD 1XO2A 4CFWB 2UZEB 4F7SB 1W98B 3B57A 1GH6B 4ZGEB 4CFXB 3HZJA 2F2CA 2W96A 1F5QB 1O9KB 2ZCFB 1H4LD 2PK2A 4Z6YA 2CZ6B 4EOLB 2CJMB 1UGSB 4AKHA 5HQ0B 2V22B 3HO8A 3MIAB 5ACBA 4F6WB 2BS4A 3X26B 1IREB 2UUEB 4BCGB 1QLBA 2EUFA 4OR5B 5LMKB 2DXBB 4Y72B 3QHWB 2QFZA 5LQFB 2QDYB 1N4MA 5IDPB 4HNUA 5IF1B 5EFQB 5L2WB 4BCFB 4ELLA 4HNVA 3BHUB 4MFDA 1ZP2A 3VYGB 2WHBB 1JSUB 2WPAB 3X24B 3EOCB 3QWLA 1OKVB 2W2HA 4OB2B 3G33B 2CZ0B 3TNWB 4BCKB 1V29B 3BG3A 4IMYB 4BCQD 3M03A 4HNTA 4OB1B 2QF7A 2DMEA 4FX3B 4M6VA 2G77A 3A8GB 2KR6A 4BCQB 4MFEA 4EOIB 1TFBA 3F5XB 4BY1X 5CEIB 4F6UB 1UNHD 2D0QB 3RGFB 1JOWA 3WVEB 1UNGD 2WEVB 2LW4A 3QXEB 4HL4A 4F7LB 2R7GA 1H26B 2UZBB 2WJ9A 3VYHB 2WMAB 2C5XB 4CFVB 5CYIB 4EOMB 1E7PA 4BCJB 4CFUB 4OGRB 1URCB 2ZPEB 3A8HB 1H25B 3QYGB 2W9ZA 2ZPHB 4BBRM 3H4CA 2ZPIB 1AHJB 4ROCA 2JGZB 1VOLA
chains in the Genus database with same CATH topology
3DL1A 4HNVA 2BS3A 4BBSM 4ELJA 1UGQB 4MFDA 4MIMA 3A8OB 2DD4B 2KMGA 3VYGB 2QQ8A 2ZPBB 3X24B 4ZGJB 2ZPFB 3QWLA 2DXCB 4JX6A 3BG5A 4NC6A 2CYZB 4OB2B 2CZ0B 4ZGDB 1UGPB 3A8MB 2ZPGB 3TW6A 4AKIA 3HHTB 1V29B 3BG3A 3QYEA 4AI6A 4HNTA 1UGRB 4OB1B 4OB3B 4HLQA 2QF7A 2AHJB 3QYBA 4M6VA 2G77A 3A8GB 2KR6A 4AKGA 4MFEA 3TW7A 2DPPB 2CZ7B 2BS2A 3KHIA 3X28B 3QZ9B 4ZGEB 4LOCA 3HBLA 3A8LB 3VKGA 3HZJA 3QYHB 4FM4B 4JX5A 2ZCFB 4QSHA 2CZ1B 2D0QB 4Z6YA 2CZ6B 3WVEB 3QZ5B 2ZZDB 3HB9A 1UGSB 4AKHA 3QXEB 4HL4A 3X25B 3HO8A 2QDJA 2BS4A 2WJ9A 3VYHB 3X26B 1E7PA 1FKMA 5EJCA 1IREB 1QLBA 4JX4A 2ZPEB 3A8HB 2DXBB 3QYGB 3BG9A 2ZPHB 2QFZA 4BBRM 2QDYB 2DD5B 3H4CA 2ZPIB 1AHJB 4OB0B 4HNUA 3VKHA 3WVDB 3X20B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QZ9 B;  2CZ0 B;  4ZGD B;  1UGP B;  3A8M B;  4ZGE B;  2ZPG B;  1UGQ B;  3VYH B;  3A8L B;  3X26 B;  3A8O B;  2DD4 B;  4FM4 B;  3QYH B;  3VYG B;  1IRE B;  2ZPE B;  3A8H B;  3HHT B;  1V29 B;  2ZCF B;  2DXB B;  3QYG B;  2CZ1 B;  2D0Q B;  2CZ6 B;  1UGR B;  2ZPB B;  3X24 B;  4OB1 B;  2ZPH B;  4OB3 B;  4ZGJ B;  2ZPF B;  3QZ5 B;  3WVE B;  2ZZD B;  2QDY B;  2DXC B;  2AHJ B;  1UGS B;  2DD5 B;  3A8G B;  3QXE B;  2ZPI B;  1AHJ B;  2CYZ B;  2DPP B;  4OB0 B;  4OB2 B;  3X25 B;  2CZ7 B;  3X28 B;  3WVD B;  3X20 B; 
#chains in the Genus database with same CATH topology
 4F6S B;  1JST B;  4ELJ A;  1JKW A;  2KMG A;  3MI9 B;  3DOG B;  2ZPB B;  1OL1 B;  2ZPF B;  3TNI B;  1H28 B;  4YOZ A;  2X1N B;  4EC9 B;  3A8M B;  2UZD B;  3POM A;  4AKI A;  5DQW A;  2W9F A;  3K7A M;  2AHJ B;  2PMI B;  4AKG A;  3TW7 A;  2DPP B;  2CZ7 B;  3TNH B;  3QZ9 B;  5HVY B;  1OIU B;  4LOC A;  3A8L B;  4EOQ B;  1GY3 B;  2BPM B;  2C5O B;  3VKG A;  4FM4 B;  3QYH B;  1OGU B;  4EOP B;  4G6L B;  1PKD B;  3TN8 B;  2QGS A;  4QSH A;  2CZ1 B;  2B9R A;  1H1R B;  2W99 A;  1O9K A;  2ZZD B;  3HB9 A;  4BCI B;  3O0G D;  1H24 B;  1H1S B;  3X25 B;  1AIS B;  2C4G B;  2I40 B;  4KRC B;  4EOO B;  4YC3 B;  3BHT B;  1D3U B;  1FKM A;  5EJC A;  4JX4 A;  4EC8 B;  2WMB B;  3BG9 A;  5ICP B;  2DD5 B;  4EOR B;  3EJ1 B;  4OB0 B;  4EOS B;  4CRL B;  1VYW B;  3X20 B;  3DL1 A;  4BCN D;  1OI9 B;  3BLH B;  2C5N B;  2DD4 B;  4BCM D;  4ROE A;  2PJQ A;  2CCH B;  4BCN B;  3DDQ B;  1G3N C;  4F7N B;  2I53 A;  1FVV B;  4BXX X;  1GUX B;  1H27 B;  4EOK B;  4ZGJ B;  5HNB B;  4JX6 A;  1E9H B;  3BG5 A;  4NC6 A;  2CYZ B;  2WFY B;  4ROD A;  2PHG A;  1UGP B;  4BY7 X;  2ZPG B;  2BKZ B;  4II5 B;  4EON B;  4UN0 A;  5HBE B;  4CFN B;  2IW8 B;  4AI6 A;  1UGR B;  4HLQ A;  1OL2 B;  1UNL D;  2UZL B;  5HBH B;  2C6T B;  1C9B A;  1FIN B;  3X28 B;  2BS2 A;  3KHI A;  4BCP B;  2G9X B;  2WIP B;  3HBL A;  1VIN A;  1KXU A;  4JX5 A;  2CCI B;  3BHV B;  5BNJ B;  4CXA B;  2WXV B;  3PO3 S;  3BLQ B;  2IVX A;  3QZ5 B;  5IDN B;  2C5V B;  5IHY A;  5I5Z B;  4EOJ B;  2IN3 A;  2QDJ A;  1H1P B;  5HBJ B;  4KRD B;  3MY5 B;  1BU2 A;  1OIY B;  1H1Q B;  4CFM B;  1TD6 A;  4BCH B;  1GUX A;  3LQ5 B;  4TTH A;  3DTO A;  3EID B;  3DJB A;  3VKH A;  3WVD B;  3MY1 B;  3NDQ A;  4BBS M;  2BS3 A;  1ENW A;  1UGQ B;  4MIM A;  4YOO A;  3A8O B;  2IW9 B;  2PK9 B;  2QQ8 A;  4F7J B;  4YOS A;  1QMZ B;  2DXC B;  3QHR B;  4F70 B;  1AD6 A;  2WIH B;  3DDP B;  3BLR B;  4ZGD B;  4NST B;  3GTM S;  5DQV A;  3TW6 A;  5FGK B;  3HHT B;  2IW6 B;  4BCO B;  3QYE A;  1OKW B;  4OB3 B;  1P5E B;  3QYB A;  4BCM B;  4I3Z B;  4CFU D;  1XO2 A;  4CFW B;  2UZE B;  4F7S B;  1W98 B;  3B57 A;  1GH6 B;  4ZGE B;  4CFX B;  3HZJ A;  2F2C A;  2W96 A;  1F5Q B;  1O9K B;  2ZCF B;  1H4L D;  2PK2 A;  4Z6Y A;  2CZ6 B;  4EOL B;  2CJM B;  1UGS B;  4AKH A;  5HQ0 B;  2V22 B;  3HO8 A;  3MIA B;  5ACB A;  4F6W B;  2BS4 A;  3X26 B;  1IRE B;  2UUE B;  4BCG B;  1QLB A;  2EUF A;  4OR5 B;  5LMK B;  2DXB B;  4Y72 B;  3QHW B;  2QFZ A;  5LQF B;  2QDY B;  1N4M A;  5IDP B;  4HNU A;  5IF1 B;  5EFQ B;  5L2W B;  4BCF B;  4ELL A;  4HNV A;  3BHU B;  4MFD A;  1ZP2 A;  3VYG B;  2WHB B;  1JSU B;  2WPA B;  3X24 B;  3EOC B;  3QWL A;  1OKV B;  2W2H A;  4OB2 B;  3G33 B;  2CZ0 B;  3TNW B;  4BCK B;  1V29 B;  3BG3 A;  4IMY B;  4BCQ D;  3M03 A;  4HNT A;  4OB1 B;  2QF7 A;  2DME A;  4FX3 B;  4M6V A;  2G77 A;  3A8G B;  2KR6 A;  4BCQ B;  4MFE A;  4EOI B;  1TFB A;  3F5X B;  4BY1 X;  5CEI B;  4F6U B;  1UNH D;  2D0Q B;  3RGF B;  1JOW A;  3WVE B;  1UNG D;  2WEV B;  2LW4 A;  3QXE B;  4HL4 A;  4F7L B;  2R7G A;  1H26 B;  2UZB B;  2WJ9 A;  3VYH B;  2WMA B;  2C5X B;  4CFV B;  5CYI B;  4EOM B;  1E7P A;  4BCJ B;  4CFU B;  4OGR B;  1URC B;  2ZPE B;  3A8H B;  1H25 B;  3QYG B;  2W9Z A;  2ZPH B;  4BBR M;  3H4C A;  2ZPI B;  1AHJ B;  4ROC A;  2JGZ B;  1VOL A; 
#chains in the Genus database with same CATH homology
 3DL1 A;  4HNV A;  2BS3 A;  4BBS M;  4ELJ A;  1UGQ B;  4MFD A;  4MIM A;  3A8O B;  2DD4 B;  2KMG A;  3VYG B;  2QQ8 A;  2ZPB B;  3X24 B;  4ZGJ B;  2ZPF B;  3QWL A;  2DXC B;  4JX6 A;  3BG5 A;  4NC6 A;  2CYZ B;  4OB2 B;  2CZ0 B;  4ZGD B;  1UGP B;  3A8M B;  2ZPG B;  3TW6 A;  4AKI A;  3HHT B;  1V29 B;  3BG3 A;  3QYE A;  4AI6 A;  4HNT A;  1UGR B;  4OB1 B;  4OB3 B;  4HLQ A;  2QF7 A;  2AHJ B;  3QYB A;  4M6V A;  2G77 A;  3A8G B;  2KR6 A;  4AKG A;  4MFE A;  3TW7 A;  2DPP B;  2CZ7 B;  2BS2 A;  3KHI A;  3X28 B;  3QZ9 B;  4ZGE B;  4LOC A;  3HBL A;  3A8L B;  3VKG A;  3HZJ A;  3QYH B;  4FM4 B;  4JX5 A;  2ZCF B;  4QSH A;  2CZ1 B;  2D0Q B;  4Z6Y A;  2CZ6 B;  3WVE B;  3QZ5 B;  2ZZD B;  3HB9 A;  1UGS B;  4AKH A;  3QXE B;  4HL4 A;  3X25 B;  3HO8 A;  2QDJ A;  2BS4 A;  2WJ9 A;  3VYH B;  3X26 B;  1E7P A;  1FKM A;  5EJC A;  1IRE B;  1QLB A;  4JX4 A;  2ZPE B;  3A8H B;  2DXB B;  3QYG B;  3BG9 A;  2ZPH B;  2QFZ A;  4BBR M;  2QDY B;  2DD5 B;  3H4C A;  2ZPI B;  1AHJ B;  4OB0 B;  4HNU A;  3VKH A;  3WVD B;  3X20 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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