3ABHA

Crystal structure of the efc/f-bar domain of human pacsin2/syndapin ii (2.0 a)
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
288
structure length
288
Chain Sequence
DSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQFEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mapping of the basic amino-acid residues responsible for tubulation and cellular protrusion by the EFC/F-BAR domain of pacsin2/Syndapin II
pubmed doi rcsb
molecule tags Endocytosis
source organism Homo sapiens
molecule keywords Protein kinase C and casein kinase substrate in neurons prot
total genus 114
structure length 288
sequence length 288
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-12-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3abhA01
4BNEA 1URUA 1Y2OA 2D1LA 5C5BB 3DYTA 3Q84A 3SOGA 3OK8A 2EFLA 3I2WA 1I4DA 3M3WA 4FZSA 1X04A 3QNIA 1WDZA 2Q13A 2RAKA 4NSWA 4DYLA 2RAIA 5C5BA 3HAJA 2Z0VA 4WPEA 1I49A 3G9GA 3ABHA 2Z0OA 3ACOA 4ATMA 2ELBA 2V0OA 1I4LA 4NQIA 4AKVA 1X03A 2X3XA 2D4CA 3Q0KA 4DCNC 3HAHA 3CAZA 2EFKA 3QE6A 1ZWWA 2X3VA 3HAIA 4WPCA 1I4TA 2FICA 2RAJA 3PLTA 2C08A 3SYVA 4AVMA 4I1QA 2YKTA 3QWEA 2X3WA 2Z0NA 4H8SA 3LLLA 2Q12A
chains in the Genus database with same CATH superfamily
2FYVA 4E81A 2N3KA 1X04A 3LVTA 4PO2A 2RAIA 3L3PA 3D51A 3VEBA 1ZYLA 4EZTA 4R5IA 3T48A 3EJQA 2MI7A 2YKTA 4M0MA 2Q13A 3T46A 3FD9A 2Z0VA 4AZIA 2F18A 4ATMA 3BUQA 2LM0A 4HY9A 4JNFA 4DCNC 2EX3B 3DPQA 4EZXA 4AZ7A 4JN4A 2F1BA 2KHOA 4B9QA 2LXYA 2OO2A 3O3MB 4NQIA 2Z8YA 1DKYA 4JWDA 2YL6A 2YI9A 2GF4A 2GA9D 2ND0A 5C5BB 4HYBA 3OK8A 3I2WA 1I4DA 3BUPA 4EZVA 4EZPA 3D2FA 3GI7A 1R34A 5E84A 2X3XA 1I4TA 3PLTA 3D4YA 2ALWA 3OWGA 2X3WA 2Z0NA 4EZQA 3LLLA 2RT6A 1QWUA 3BVWA 2F7PA 1URUA 1SU8A 3DX0A 3Q84A 3T47A 4FZSA 3BUDA 3QNIA 3L3OM 4AZGA 4R5KA 2OW6A 1YWMA 3DX4A 3BVTA 4EZZA 4AKVA 1X03A 3Q0KA 1R33A 2YIVX 4KIKB 4EZSA 4JWEA 2ND1A 1U00A 3T49A 3DYTA 1GNTA 2RAKA 3DX2A 4EZYA 4G6QA 2F7QA 1QX1A 2F1AA 4FM3A 3QWEA 2WINM 2QFFA 3CVRA 3RV1A 4IWQA 5C5BA 3D4ZA 1TQWA 3G9GA 3B53X 4EZWA 4R5LA 4AZBA 3HAHA 2EFKA 2PY6A 2F7OA 1LQ7A 3BUBA 4IWOA 4FZOA 4HR1B 1PS3A 3CZNA 2YLLA 3BVXA 4AZCA 4JLCA 5TKYA 3BVVA 2WYIA 4EZRA 1O7DB 4JWIA 4JNEA 2JNKA 3DPOA 3CZSA 1UPXA 3ERCC 3M3WA 1GN9A 2OZNB 3CKDA 3KAWA 3D2EA 1E9VA 2D4CA 4D8JA 3EJTA 1OA0A 3EJUA 1E2UA 4I1QA 3LMFA 4R5GA 4IM3A 3HAIA 4BNEA 2D1LA 2YL5A 3I39X 2Z0OA 4IWPA 4IM0A 3O3NB 1R5EA 2OBMA 4JWCA 3DDFA 1ZWWA 2YIAA 2RAJA 4AVMA 2YIBA 3F7WA 4E3CA 3T4AG 1DKZA 3UITA 2PMRA 5FIGA 4JL9A 2ZXQA 3BLBA 3B51X 4H6IA 1JQKA 2NCZA 3CV5A 4HR1A 1O7DC 2WYHA 5FLEX 4FZPA 2FICA 3EJSA 1HTYA 4IW0A 4AZ5A 3DX1A 3C7NA 4UDYX 2GAFD 1SU6A 3VEAA 4F00A 5KBPA 3A98A 3ACOA 4EZNA 3RPMA 3BVUA 3DDGA 2X5CA 2X3VA 2C08A 1TQSA 2OBLA 4UDXX 3DPPA 1MJGA 4H6HA 1SUFA 2EFLA 2YL9A 4DYLA 1OAOA 3HAJA 2QXLA 4WPEA 1I4LA 3B52X 3BUIA 2YLAA 2O0I1 3I04A 1E1DA 2OW7A 3SOGA 1W9MA 3QNJA 4KIKA 1GNLA 2YI8A 3D50A 4NPHA 3EJPA 1DKXA 3ER9B 2F7RA 2YL8A 4R5JA 1HXKA 3EJRA 3I01A 1Y2OA 1TQUA 3ZEDA 3QA8A 2EWFA 1OA1A 3VKHA 1I49A 3D52A 1SU7A 3O3OB 4EZOA 3QE6A 3KAVA 2QKWA 3OHXM 1HWWA 4H8SA 4WPCA 4EZUA 3KDRA 3RV0A 4AZ6A 4F01A 4AZCB 1TQTA 1WDZA 4NSWA 2JNSA 4AZHA 3ABHA 3DX3A 2ELBA 2V0OA 3CAZA 4IM2A 1QWNA 3SYVA 3ER8C 1TQVA 2Q12A
chains in the Genus database with same CATH topology
4BNEA 1URUA 1Y2OA 2D1LA 5C5BB 3DYTA 3Q84A 3SOGA 3OK8A 2EFLA 3I2WA 1I4DA 3M3WA 4FZSA 1X04A 3QNIA 1WDZA 2Q13A 2RAKA 4NSWA 4DYLA 2RAIA 5C5BA 3HAJA 2Z0VA 4WPEA 1I49A 3G9GA 3ABHA 2Z0OA 3ACOA 4ATMA 2ELBA 2V0OA 1I4LA 4NQIA 4AKVA 1X03A 2X3XA 2D4CA 3Q0KA 4DCNC 3HAHA 3CAZA 2EFKA 3QE6A 1ZWWA 2X3VA 3HAIA 4WPCA 1I4TA 2FICA 2RAJA 3PLTA 2C08A 3SYVA 4AVMA 4I1QA 2YKTA 3QWEA 2X3WA 2Z0NA 4H8SA 3LLLA 2Q12A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BNE A;  1URU A;  1Y2O A;  2D1L A;  5C5B B;  3DYT A;  3Q84 A;  3SOG A;  3OK8 A;  2EFL A;  3I2W A;  1I4D A;  3M3W A;  4FZS A;  1X04 A;  3QNI A;  1WDZ A;  2Q13 A;  2RAK A;  4NSW A;  4DYL A;  2RAI A;  5C5B A;  3HAJ A;  2Z0V A;  4WPE A;  1I49 A;  3G9G A;  3ABH A;  2Z0O A;  3ACO A;  4ATM A;  2ELB A;  2V0O A;  1I4L A;  4NQI A;  4AKV A;  1X03 A;  2X3X A;  2D4C A;  3Q0K A;  4DCN C;  3HAH A;  3CAZ A;  2EFK A;  3QE6 A;  1ZWW A;  2X3V A;  3HAI A;  4WPC A;  1I4T A;  2FIC A;  2RAJ A;  3PLT A;  2C08 A;  3SYV A;  4AVM A;  4I1Q A;  2YKT A;  3QWE A;  2X3W A;  2Z0N A;  4H8S A;  3LLL A;  2Q12 A; 
#chains in the Genus database with same CATH topology
 2FYV A;  4E81 A;  2N3K A;  1X04 A;  3LVT A;  4PO2 A;  2RAI A;  3L3P A;  3D51 A;  3VEB A;  1ZYL A;  4EZT A;  4R5I A;  3T48 A;  3EJQ A;  2MI7 A;  2YKT A;  4M0M A;  2Q13 A;  3T46 A;  3FD9 A;  2Z0V A;  4AZI A;  2F18 A;  4ATM A;  3BUQ A;  2LM0 A;  4HY9 A;  4JNF A;  4DCN C;  2EX3 B;  3DPQ A;  4EZX A;  4AZ7 A;  4JN4 A;  2F1B A;  2KHO A;  4B9Q A;  2LXY A;  2OO2 A;  3O3M B;  4NQI A;  2Z8Y A;  1DKY A;  4JWD A;  2YL6 A;  2YI9 A;  2GF4 A;  2GA9 D;  2ND0 A;  5C5B B;  4HYB A;  3OK8 A;  3I2W A;  1I4D A;  3BUP A;  4EZV A;  4EZP A;  3D2F A;  3GI7 A;  1R34 A;  5E84 A;  2X3X A;  1I4T A;  3PLT A;  3D4Y A;  2ALW A;  3OWG A;  2X3W A;  2Z0N A;  4EZQ A;  3LLL A;  2RT6 A;  1QWU A;  3BVW A;  2F7P A;  1URU A;  1SU8 A;  3DX0 A;  3Q84 A;  3T47 A;  4FZS A;  3BUD A;  3QNI A;  3L3O M;  4AZG A;  4R5K A;  2OW6 A;  1YWM A;  3DX4 A;  3BVT A;  4EZZ A;  4AKV A;  1X03 A;  3Q0K A;  1R33 A;  2YIV X;  4KIK B;  4EZS A;  4JWE A;  2ND1 A;  1U00 A;  3T49 A;  3DYT A;  1GNT A;  2RAK A;  3DX2 A;  4EZY A;  4G6Q A;  2F7Q A;  1QX1 A;  2F1A A;  4FM3 A;  3QWE A;  2WIN M;  2QFF A;  3CVR A;  3RV1 A;  4IWQ A;  5C5B A;  3D4Z A;  1TQW A;  3G9G A;  3B53 X;  4EZW A;  4R5L A;  4AZB A;  3HAH A;  2EFK A;  2PY6 A;  2F7O A;  1LQ7 A;  3BUB A;  4IWO A;  4FZO A;  4HR1 B;  1PS3 A;  3CZN A;  2YLL A;  3BVX A;  4AZC A;  4JLC A;  5TKY A;  3BVV A;  2WYI A;  4EZR A;  1O7D B;  4JWI A;  4JNE A;  2JNK A;  3DPO A;  3CZS A;  1UPX A;  3ERC C;  3M3W A;  1GN9 A;  2OZN B;  3CKD A;  3KAW A;  3D2E A;  1E9V A;  2D4C A;  4D8J A;  3EJT A;  1OA0 A;  3EJU A;  1E2U A;  4I1Q A;  3LMF A;  4R5G A;  4IM3 A;  3HAI A;  4BNE A;  2D1L A;  2YL5 A;  3I39 X;  2Z0O A;  4IWP A;  4IM0 A;  3O3N B;  1R5E A;  2OBM A;  4JWC A;  3DDF A;  1ZWW A;  2YIA A;  2RAJ A;  4AVM A;  2YIB A;  3F7W A;  4E3C A;  3T4A G;  1DKZ A;  3UIT A;  2PMR A;  5FIG A;  4JL9 A;  2ZXQ A;  3BLB A;  3B51 X;  4H6I A;  1JQK A;  2NCZ A;  3CV5 A;  4HR1 A;  1O7D C;  2WYH A;  5FLE X;  4FZP A;  2FIC A;  3EJS A;  1HTY A;  4IW0 A;  4AZ5 A;  3DX1 A;  3C7N A;  4UDY X;  2GAF D;  1SU6 A;  3VEA A;  4F00 A;  5KBP A;  3A98 A;  3ACO A;  4EZN A;  3RPM A;  3BVU A;  3DDG A;  2X5C A;  2X3V A;  2C08 A;  1TQS A;  2OBL A;  4UDX X;  3DPP A;  1MJG A;  4H6H A;  1SUF A;  2EFL A;  2YL9 A;  4DYL A;  1OAO A;  3HAJ A;  2QXL A;  4WPE A;  1I4L A;  3B52 X;  3BUI A;  2YLA A;  2O0I 1;  3I04 A;  1E1D A;  2OW7 A;  3SOG A;  1W9M A;  3QNJ A;  4KIK A;  1GNL A;  2YI8 A;  3D50 A;  4NPH A;  3EJP A;  1DKX A;  3ER9 B;  2F7R A;  2YL8 A;  4R5J A;  1HXK A;  3EJR A;  3I01 A;  1Y2O A;  1TQU A;  3ZED A;  3QA8 A;  2EWF A;  1OA1 A;  3VKH A;  1I49 A;  3D52 A;  1SU7 A;  3O3O B;  4EZO A;  3QE6 A;  3KAV A;  2QKW A;  3OHX M;  1HWW A;  4H8S A;  4WPC A;  4EZU A;  3KDR A;  3RV0 A;  4AZ6 A;  4F01 A;  4AZC B;  1TQT A;  1WDZ A;  4NSW A;  2JNS A;  4AZH A;  3ABH A;  3DX3 A;  2ELB A;  2V0O A;  3CAZ A;  4IM2 A;  1QWN A;  3SYV A;  3ER8 C;  1TQV A;  2Q12 A; 
#chains in the Genus database with same CATH homology
 4BNE A;  1URU A;  1Y2O A;  2D1L A;  5C5B B;  3DYT A;  3Q84 A;  3SOG A;  3OK8 A;  2EFL A;  3I2W A;  1I4D A;  3M3W A;  4FZS A;  1X04 A;  3QNI A;  1WDZ A;  2Q13 A;  2RAK A;  4NSW A;  4DYL A;  2RAI A;  5C5B A;  3HAJ A;  2Z0V A;  4WPE A;  1I49 A;  3G9G A;  3ABH A;  2Z0O A;  3ACO A;  4ATM A;  2ELB A;  2V0O A;  1I4L A;  4NQI A;  4AKV A;  1X03 A;  2X3X A;  2D4C A;  3Q0K A;  4DCN C;  3HAH A;  3CAZ A;  2EFK A;  3QE6 A;  1ZWW A;  2X3V A;  3HAI A;  4WPC A;  1I4T A;  2FIC A;  2RAJ A;  3PLT A;  2C08 A;  3SYV A;  4AVM A;  4I1Q A;  2YKT A;  3QWE A;  2X3W A;  2Z0N A;  4H8S A;  3LLL A;  2Q12 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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