3ACOA

Crystal structure of the efc/f-bar domain of human pacsin2/syndapin ii (2.7 a)
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
284
structure length
284
Chain Sequence
DSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mapping of the basic amino-acid residues responsible for tubulation and cellular protrusion by the EFC/F-BAR domain of pacsin2/Syndapin II
pubmed doi rcsb
molecule tags Endocytosis
source organism Homo sapiens
molecule keywords Protein kinase C and casein kinase substrate in neurons prot
total genus 101
structure length 284
sequence length 284
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3acoA01
1X03A 4NQIA 1ZWWA 3OK8A 4ATMA 2EFKA 5C5BB 2X3WA 4AKVA 4WPCA 3LLLA 2D1LA 4AVMA 3QNIA 3PLTA 5C5BA 2EFLA 4I1QA 2Z0OA 2D4CA 1I4TA 3CAZA 4DYLA 2Z0VA 3ACOA 3Q84A 3I2WA 3HAHA 2Z0NA 4WPEA 2X3XA 2RAKA 2RAJA 4H8SA 2Q12A 2X3VA 2V0OA 3Q0KA 1Y2OA 4FZSA 1URUA 2FICA 3M3WA 3SOGA 3QWEA 4BNEA 1I4LA 3HAJA 2C08A 2Q13A 3HAIA 3QE6A 1I4DA 2ELBA 2RAIA 3G9GA 3DYTA 4DCNC 4NSWA 1WDZA 1X04A 1I49A 3SYVA 3ABHA 2YKTA
chains in the Genus database with same CATH superfamily
4FZPA 2Z0OA 2N3KA 4FM3A 4IWOA 3T47A 4EZZA 2Z8YA 1GNTA 3BUPA 1O7DB 4F00A 3SOGA 3BVVA 3QE6A 1MJGA 4NSWA 1HTYA 3ABHA 2YLAA 4AZGA 1TQWA 4AKVA 3A98A 3ER8C 1QWNA 1I4TA 1OA1A 3T48A 4AZBA 2Z0VA 3ACOA 3UITA 2KHOA 3O3NB 1R33A 1URUA 2C08A 3OHXM 3DYTA 4DCNC 3D51A 2ND1A 4AZCB 2YKTA 3DPOA 2X3WA 2PY6A 3KAWA 3DX2A 4R5JA 2PMRA 4R5IA 1U00A 3VEBA 4KIKB 3EJPA 2ND0A 3VEAA 3CVRA 4EZOA 2JNKA 4EZTA 1WDZA 2OW6A 3SYVA 2O0I1 1X03A 4UDXX 2YIAA 2YLLA 3EJSA 3L3OM 2YL8A 3D52A 2RAJA 3BUQA 3ZEDA 1R5EA 3BUBA 1X04A 3LLLA 2YI8A 1OA0A 3DX0A 4EZWA 1LQ7A 2V0OA 2GAFD 4FZSA 4R5LA 2FICA 1TQTA 2LXYA 4EZUA 1I4LA 3CZNA 2F7OA 4EZRA 4D8JA 3QNIA 3PLTA 3O3MB 3KAVA 3QA8A 3ER9B 2GF4A 2ALWA 1QX1A 1E2UA 3Q0KA 3B52X 4FZOA 4E3CA 2RAIA 5FIGA 1SU6A 4EZSA 4AVMA 4IWQA 5C5BA 5TKYA 3I2WA 4IM2A 3BVXA 2X3XA 3B53X 4HR1A 1GNLA 1QWUA 4AZIA 1PS3A 3T46A 1UPXA 1I49A 2EFKA 3D2EA 3CV5A 4F01A 2OW7A 2YL9A 2RAKA 3BVTA 1Y2OA 2OO2A 1YWMA 2QXLA 4AZ6A 1DKXA 2F1AA 2OBMA 1HXKA 2D1LA 2RT6A 3CAZA 3D50A 4IM3A 2F7QA 3DPPA 4H6HA 4JNEA 4EZYA 4EZVA 3ERCC 2EWFA 3QWEA 3D4YA 3QNJA 3RV1A 2GA9D 5E84A 2NCZA 4NQIA 4IWPA 2JNSA 2EFLA 3BUIA 2WINM 4DYLA 4JWIA 2LM0A 3T4AG 1TQUA 2EX3B 1SU7A 3CKDA 4BNEA 3EJQA 4EZQA 3B51X 3GI7A 2OBLA 1SU8A 1E1DA 5C5BB 3LVTA 2QKWA 3D2FA 2WYIA 3O3OB 3BVWA 4HR1B 4WPEA 5KBPA 1TQVA 1ZYLA 4HYBA 4JL9A 3BVUA 2MI7A 2Q13A 1TQSA 2ELBA 3I39X 2WYHA 3EJRA 1W9MA 4B9QA 1JQKA 4JWDA 4R5KA 2YL6A 3F7WA 2F7RA 4H8SA 2X5CA 4JLCA 3M3WA 3HAJA 3T49A 3DX1A 2F1BA 3L3PA 1GN9A 4IM0A 3OK8A 3RV0A 4WPCA 1O7DC 4NPHA 2D4CA 5FLEX 1OAOA 2F7PA 4IW0A 4AZHA 1HWWA 4AZ7A 4EZPA 3DDFA 4JWEA 4G6QA 2OZNB 3LMFA 3C7NA 3EJUA 4UDYX 2YIBA 4EZNA 3HAIA 1I4DA 3DPQA 1SUFA 3G9GA 4R5GA 3VKHA 4AZCA 4ATMA 2YI9A 2QFFA 3BUDA 1DKZA 4HY9A 3Q84A 1DKYA 3EJTA 3HAHA 3KDRA 1R34A 2FYVA 3OWGA 4KIKA 3I04A 4JNFA 2ZXQA 3DX3A 3FD9A 3DX4A 1E9VA 4EZXA 4AZ5A 1ZWWA 4H6IA 3CZSA 4M0MA 4JN4A 4I1QA 4E81A 4PO2A 3DDGA 4JWCA 2YL5A 3BLBA 2Z0NA 2Q12A 2X3VA 3RPMA 3I01A 2YIVX 3D4ZA 2F18A
chains in the Genus database with same CATH topology
1X03A 4NQIA 1ZWWA 3OK8A 4ATMA 2EFKA 5C5BB 2X3WA 4AKVA 4WPCA 3LLLA 2D1LA 4AVMA 3QNIA 3PLTA 5C5BA 2EFLA 4I1QA 2Z0OA 2D4CA 1I4TA 3CAZA 4DYLA 2Z0VA 3ACOA 3Q84A 3I2WA 3HAHA 2Z0NA 4WPEA 2X3XA 2RAKA 2RAJA 4H8SA 2Q12A 2X3VA 2V0OA 3Q0KA 1Y2OA 4FZSA 1URUA 2FICA 3M3WA 3SOGA 3QWEA 4BNEA 1I4LA 3HAJA 2C08A 2Q13A 3HAIA 3QE6A 1I4DA 2ELBA 2RAIA 3G9GA 3DYTA 4DCNC 4NSWA 1WDZA 1X04A 1I49A 3SYVA 3ABHA 2YKTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1X03 A;  4NQI A;  1ZWW A;  3OK8 A;  4ATM A;  2EFK A;  5C5B B;  2X3W A;  4AKV A;  4WPC A;  3LLL A;  2D1L A;  4AVM A;  3QNI A;  3PLT A;  5C5B A;  2EFL A;  4I1Q A;  2Z0O A;  2D4C A;  1I4T A;  3CAZ A;  4DYL A;  2Z0V A;  3ACO A;  3Q84 A;  3I2W A;  3HAH A;  2Z0N A;  4WPE A;  2X3X A;  2RAK A;  2RAJ A;  4H8S A;  2Q12 A;  2X3V A;  2V0O A;  3Q0K A;  1Y2O A;  4FZS A;  1URU A;  2FIC A;  3M3W A;  3SOG A;  3QWE A;  4BNE A;  1I4L A;  3HAJ A;  2C08 A;  2Q13 A;  3HAI A;  3QE6 A;  1I4D A;  2ELB A;  2RAI A;  3G9G A;  3DYT A;  4DCN C;  4NSW A;  1WDZ A;  1X04 A;  1I49 A;  3SYV A;  3ABH A;  2YKT A; 
#chains in the Genus database with same CATH topology
 4FZP A;  2Z0O A;  2N3K A;  4FM3 A;  4IWO A;  3T47 A;  4EZZ A;  2Z8Y A;  1GNT A;  3BUP A;  1O7D B;  4F00 A;  3SOG A;  3BVV A;  3QE6 A;  1MJG A;  4NSW A;  1HTY A;  3ABH A;  2YLA A;  4AZG A;  1TQW A;  4AKV A;  3A98 A;  3ER8 C;  1QWN A;  1I4T A;  1OA1 A;  3T48 A;  4AZB A;  2Z0V A;  3ACO A;  3UIT A;  2KHO A;  3O3N B;  1R33 A;  1URU A;  2C08 A;  3OHX M;  3DYT A;  4DCN C;  3D51 A;  2ND1 A;  4AZC B;  2YKT A;  3DPO A;  2X3W A;  2PY6 A;  3KAW A;  3DX2 A;  4R5J A;  2PMR A;  4R5I A;  1U00 A;  3VEB A;  4KIK B;  3EJP A;  2ND0 A;  3VEA A;  3CVR A;  4EZO A;  2JNK A;  4EZT A;  1WDZ A;  2OW6 A;  3SYV A;  2O0I 1;  1X03 A;  4UDX X;  2YIA A;  2YLL A;  3EJS A;  3L3O M;  2YL8 A;  3D52 A;  2RAJ A;  3BUQ A;  3ZED A;  1R5E A;  3BUB A;  1X04 A;  3LLL A;  2YI8 A;  1OA0 A;  3DX0 A;  4EZW A;  1LQ7 A;  2V0O A;  2GAF D;  4FZS A;  4R5L A;  2FIC A;  1TQT A;  2LXY A;  4EZU A;  1I4L A;  3CZN A;  2F7O A;  4EZR A;  4D8J A;  3QNI A;  3PLT A;  3O3M B;  3KAV A;  3QA8 A;  3ER9 B;  2GF4 A;  2ALW A;  1QX1 A;  1E2U A;  3Q0K A;  3B52 X;  4FZO A;  4E3C A;  2RAI A;  5FIG A;  1SU6 A;  4EZS A;  4AVM A;  4IWQ A;  5C5B A;  5TKY A;  3I2W A;  4IM2 A;  3BVX A;  2X3X A;  3B53 X;  4HR1 A;  1GNL A;  1QWU A;  4AZI A;  1PS3 A;  3T46 A;  1UPX A;  1I49 A;  2EFK A;  3D2E A;  3CV5 A;  4F01 A;  2OW7 A;  2YL9 A;  2RAK A;  3BVT A;  1Y2O A;  2OO2 A;  1YWM A;  2QXL A;  4AZ6 A;  1DKX A;  2F1A A;  2OBM A;  1HXK A;  2D1L A;  2RT6 A;  3CAZ A;  3D50 A;  4IM3 A;  2F7Q A;  3DPP A;  4H6H A;  4JNE A;  4EZY A;  4EZV A;  3ERC C;  2EWF A;  3QWE A;  3D4Y A;  3QNJ A;  3RV1 A;  2GA9 D;  5E84 A;  2NCZ A;  4NQI A;  4IWP A;  2JNS A;  2EFL A;  3BUI A;  2WIN M;  4DYL A;  4JWI A;  2LM0 A;  3T4A G;  1TQU A;  2EX3 B;  1SU7 A;  3CKD A;  4BNE A;  3EJQ A;  4EZQ A;  3B51 X;  3GI7 A;  2OBL A;  1SU8 A;  1E1D A;  5C5B B;  3LVT A;  2QKW A;  3D2F A;  2WYI A;  3O3O B;  3BVW A;  4HR1 B;  4WPE A;  5KBP A;  1TQV A;  1ZYL A;  4HYB A;  4JL9 A;  3BVU A;  2MI7 A;  2Q13 A;  1TQS A;  2ELB A;  3I39 X;  2WYH A;  3EJR A;  1W9M A;  4B9Q A;  1JQK A;  4JWD A;  4R5K A;  2YL6 A;  3F7W A;  2F7R A;  4H8S A;  2X5C A;  4JLC A;  3M3W A;  3HAJ A;  3T49 A;  3DX1 A;  2F1B A;  3L3P A;  1GN9 A;  4IM0 A;  3OK8 A;  3RV0 A;  4WPC A;  1O7D C;  4NPH A;  2D4C A;  5FLE X;  1OAO A;  2F7P A;  4IW0 A;  4AZH A;  1HWW A;  4AZ7 A;  4EZP A;  3DDF A;  4JWE A;  4G6Q A;  2OZN B;  3LMF A;  3C7N A;  3EJU A;  4UDY X;  2YIB A;  4EZN A;  3HAI A;  1I4D A;  3DPQ A;  1SUF A;  3G9G A;  4R5G A;  3VKH A;  4AZC A;  4ATM A;  2YI9 A;  2QFF A;  3BUD A;  1DKZ A;  4HY9 A;  3Q84 A;  1DKY A;  3EJT A;  3HAH A;  3KDR A;  1R34 A;  2FYV A;  3OWG A;  4KIK A;  3I04 A;  4JNF A;  2ZXQ A;  3DX3 A;  3FD9 A;  3DX4 A;  1E9V A;  4EZX A;  4AZ5 A;  1ZWW A;  4H6I A;  3CZS A;  4M0M A;  4JN4 A;  4I1Q A;  4E81 A;  4PO2 A;  3DDG A;  4JWC A;  2YL5 A;  3BLB A;  2Z0N A;  2Q12 A;  2X3V A;  3RPM A;  3I01 A;  2YIV X;  3D4Z A;  2F18 A; 
#chains in the Genus database with same CATH homology
 1X03 A;  4NQI A;  1ZWW A;  3OK8 A;  4ATM A;  2EFK A;  5C5B B;  2X3W A;  4AKV A;  4WPC A;  3LLL A;  2D1L A;  4AVM A;  3QNI A;  3PLT A;  5C5B A;  2EFL A;  4I1Q A;  2Z0O A;  2D4C A;  1I4T A;  3CAZ A;  4DYL A;  2Z0V A;  3ACO A;  3Q84 A;  3I2W A;  3HAH A;  2Z0N A;  4WPE A;  2X3X A;  2RAK A;  2RAJ A;  4H8S A;  2Q12 A;  2X3V A;  2V0O A;  3Q0K A;  1Y2O A;  4FZS A;  1URU A;  2FIC A;  3M3W A;  3SOG A;  3QWE A;  4BNE A;  1I4L A;  3HAJ A;  2C08 A;  2Q13 A;  3HAI A;  3QE6 A;  1I4D A;  2ELB A;  2RAI A;  3G9G A;  3DYT A;  4DCN C;  4NSW A;  1WDZ A;  1X04 A;  1I49 A;  3SYV A;  3ABH A;  2YKT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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