3HAHA

Crystal structure of human pacsin1 f-bar domain (c2 lattice)
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
289
structure length
269
Chain Sequence
TDSFWEVGNYKRTVKRIDDGHRLCNDLMNCVQERAKIEKAYGQQLTDWAKRWRQLIEKGPQYGSLERAWGAIMTEADKVSELHQEVKNNLLNEDLEKVKNWQKDAYHKQIMGGFKETKEAEDGFRKAQKPWAKKMKELEAAKKAYHLACKEEKLAMQDKVDKCKQDVQKTQEKYEKVLEDVGKTTPQYMENMEQVFEQCQQFEEKRLVFLKEVLLDIKRHLNLAENSSYIHVYRELEQAIRGADAQEDLRWFRSTSGPGMPMNWPQFEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular mechanism of membrane constriction and tubulation mediated by the F-BAR protein Pacsin/Syndapin.
pubmed doi rcsb
molecule tags Endocytosis
source organism Homo sapiens
molecule keywords human PACSIN1 F-BAR
total genus 113
structure length 269
sequence length 289
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-05-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3hahA01
3I2WA 1I4TA 4WPEA 3ACOA 2X3WA 4ATMA 2V0OA 4AVMA 1X03A 3PLTA 5C5BA 3QE6A 2RAJA 2Z0NA 2EFKA 2RAKA 2X3VA 3LLLA 4DYLA 3QNIA 3ABHA 2FICA 3OK8A 2EFLA 2Z0VA 4H8SA 5C5BB 2C08A 4NQIA 1I4DA 4BNEA 2D1LA 4DCNC 3G9GA 1I4LA 3Q84A 4I1QA 3DYTA 3Q0KA 3SYVA 3M3WA 1URUA 2ELBA 2Q12A 2D4CA 2X3XA 4NSWA 2Z0OA 4AKVA 2YKTA 3CAZA 1I49A 1WDZA 1X04A 3HAJA 4FZSA 3HAIA 2RAIA 3SOGA 3HAHA 2Q13A 1ZWWA 4WPCA 3QWEA 1Y2OA
chains in the Genus database with same CATH superfamily
4E3CA 3D2EA 4IW0A 1X03A 2OW6A 3LLLA 2GF4A 2EWFA 2WINM 4EZOA 1WDZA 4B9QA 3B51X 3ER8C 2YI8A 4WPCA 1SUFA 3LMFA 3CZNA 3OWGA 4EZWA 2D1LA 4I1QA 3BVUA 3CZSA 2YL8A 3EJSA 2YI9A 1DKXA 1X04A 2F7RA 3I39X 2PMRA 3QWEA 4HR1A 4EZRA 4KIKA 4EZXA 1QX1A 3OHXM 3OK8A 3EJQA 3LVTA 2YLAA 3SYVA 2ND1A 2YL5A 3DX3A 2ND0A 4JL9A 2QFFA 1TQSA 4JWEA 1MJGA 2EX3B 4JWIA 3Q0KA 3BUIA 2ALWA 4IM2A 2OZNB 4E81A 2OBLA 2X3WA 3RPMA 3BUPA 5C5BA 2YIVX 1E2UA 2YL6A 4AZ6A 2JNKA 1HTYA 3EJPA 5E84A 1GN9A 3T47A 3DYTA 2GAFD 1URUA 3CKDA 3BUQA 3T46A 4IM3A 4AZIA 3SOGA 3BVTA 3EJTA 4AZCA 3BVXA 1R34A 4IWOA 2YLLA 3B53X 4R5LA 2QKWA 3D2FA 3Q84A 4F00A 4AKVA 3HAJA 3DX4A 2ZXQA 4JNFA 3CVRA 1TQUA 2N3KA 3VEBA 2X3VA 2WYHA 2MI7A 3G9GA 4UDYX 3O3NB 5KBPA 1OA0A 3L3PA 3BUBA 3I04A 4M0MA 2GA9D 2V0OA 3DDGA 3I01A 3RV1A 4FM3A 4FZOA 3T49A 4HY9A 4NQIA 3BVVA 2WYIA 4EZQA 1OA1A 4JWDA 4NSWA 3RV0A 4EZTA 3D50A 3HAIA 4PO2A 4G6QA 3DPQA 4ATMA 3QE6A 2RT6A 2Z0VA 3VEAA 1I4LA 2X3XA 4IM0A 3DX1A 1I49A 4FZSA 5FIGA 4EZNA 3GI7A 4EZPA 2Z0NA 3KAVA 1PS3A 2C08A 4H6HA 3D51A 2X5CA 3VKHA 2Z0OA 2RAIA 1HXKA 4AZHA 4WPEA 4HYBA 3DDFA 2OO2A 1E9VA 2F7QA 1I4DA 3BUDA 4AZBA 2O0I1 1O7DB 3M3WA 5TKYA 3DPPA 4H6IA 4NPHA 3B52X 1TQVA 4EZSA 3HAHA 2YIBA 2F1AA 1I4TA 1TQTA 3ZEDA 4AZGA 2PY6A 1SU7A 4AZCB 2RAJA 1SU6A 3QNIA 3DX2A 1DKZA 3DPOA 4AZ5A 3QNJA 1TQWA 2FYVA 3O3MB 2LXYA 4EZZA 1W9MA 4JNEA 2Q13A 3T48A 3QA8A 2F7PA 3D52A 2F7OA 4AZ7A 4F01A 4EZVA 1GNTA 5FLEX 2F1BA 3KAWA 4IWQA 1JQKA 3EJRA 3EJUA 2YL9A 4DYLA 2LM0A 2Z8YA 1DKYA 1UPXA 1HWWA 4JN4A 3O3OB 2NCZA 3DX0A 4JLCA 1ZWWA 3ACOA 4R5IA 4R5GA 1E1DA 4JWCA 3L3OM 4HR1B 4KIKB 1ZYLA 3ER9B 1QWNA 3BVWA 2OW7A 1R5EA 4H8SA 2EFLA 3T4AG 2ELBA 3ERCC 3BLBA 3CAZA 4R5KA 2KHOA 1GNLA 1R33A 1YWMA 4AVMA 3ABHA 3FD9A 5C5BB 4BNEA 4DCNC 2D4CA 4R5JA 2QXLA 1OAOA 1SU8A 3C7NA 1Y2OA 3I2WA 1O7DC 2JNSA 3UITA 1U00A 3PLTA 4FZPA 2EFKA 2RAKA 3F7WA 3CV5A 2FICA 2YIAA 3KDRA 4UDXX 4IWPA 3A98A 3D4YA 4EZUA 2Q12A 4EZYA 2YKTA 2F18A 1QWUA 3D4ZA 2OBMA 4D8JA 1LQ7A
chains in the Genus database with same CATH topology
3I2WA 1I4TA 4WPEA 3ACOA 2X3WA 4ATMA 2V0OA 4AVMA 1X03A 3PLTA 5C5BA 3QE6A 2RAJA 2Z0NA 2EFKA 2RAKA 2X3VA 3LLLA 4DYLA 3QNIA 3ABHA 2FICA 3OK8A 2EFLA 2Z0VA 4H8SA 5C5BB 2C08A 4NQIA 1I4DA 4BNEA 2D1LA 4DCNC 3G9GA 1I4LA 3Q84A 4I1QA 3DYTA 3Q0KA 3SYVA 3M3WA 1URUA 2ELBA 2Q12A 2D4CA 2X3XA 4NSWA 2Z0OA 4AKVA 2YKTA 3CAZA 1I49A 1WDZA 1X04A 3HAJA 4FZSA 3HAIA 2RAIA 3SOGA 3HAHA 2Q13A 1ZWWA 4WPCA 3QWEA 1Y2OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I2W A;  1I4T A;  4WPE A;  3ACO A;  2X3W A;  4ATM A;  2V0O A;  4AVM A;  1X03 A;  3PLT A;  5C5B A;  3QE6 A;  2RAJ A;  2Z0N A;  2EFK A;  2RAK A;  2X3V A;  3LLL A;  4DYL A;  3QNI A;  3ABH A;  2FIC A;  3OK8 A;  2EFL A;  2Z0V A;  4H8S A;  5C5B B;  2C08 A;  4NQI A;  1I4D A;  4BNE A;  2D1L A;  4DCN C;  3G9G A;  1I4L A;  3Q84 A;  4I1Q A;  3DYT A;  3Q0K A;  3SYV A;  3M3W A;  1URU A;  2ELB A;  2Q12 A;  2D4C A;  2X3X A;  4NSW A;  2Z0O A;  4AKV A;  2YKT A;  3CAZ A;  1I49 A;  1WDZ A;  1X04 A;  3HAJ A;  4FZS A;  3HAI A;  2RAI A;  3SOG A;  3HAH A;  2Q13 A;  1ZWW A;  4WPC A;  3QWE A;  1Y2O A; 
#chains in the Genus database with same CATH topology
 4E3C A;  3D2E A;  4IW0 A;  1X03 A;  2OW6 A;  3LLL A;  2GF4 A;  2EWF A;  2WIN M;  4EZO A;  1WDZ A;  4B9Q A;  3B51 X;  3ER8 C;  2YI8 A;  4WPC A;  1SUF A;  3LMF A;  3CZN A;  3OWG A;  4EZW A;  2D1L A;  4I1Q A;  3BVU A;  3CZS A;  2YL8 A;  3EJS A;  2YI9 A;  1DKX A;  1X04 A;  2F7R A;  3I39 X;  2PMR A;  3QWE A;  4HR1 A;  4EZR A;  4KIK A;  4EZX A;  1QX1 A;  3OHX M;  3OK8 A;  3EJQ A;  3LVT A;  2YLA A;  3SYV A;  2ND1 A;  2YL5 A;  3DX3 A;  2ND0 A;  4JL9 A;  2QFF A;  1TQS A;  4JWE A;  1MJG A;  2EX3 B;  4JWI A;  3Q0K A;  3BUI A;  2ALW A;  4IM2 A;  2OZN B;  4E81 A;  2OBL A;  2X3W A;  3RPM A;  3BUP A;  5C5B A;  2YIV X;  1E2U A;  2YL6 A;  4AZ6 A;  2JNK A;  1HTY A;  3EJP A;  5E84 A;  1GN9 A;  3T47 A;  3DYT A;  2GAF D;  1URU A;  3CKD A;  3BUQ A;  3T46 A;  4IM3 A;  4AZI A;  3SOG A;  3BVT A;  3EJT A;  4AZC A;  3BVX A;  1R34 A;  4IWO A;  2YLL A;  3B53 X;  4R5L A;  2QKW A;  3D2F A;  3Q84 A;  4F00 A;  4AKV A;  3HAJ A;  3DX4 A;  2ZXQ A;  4JNF A;  3CVR A;  1TQU A;  2N3K A;  3VEB A;  2X3V A;  2WYH A;  2MI7 A;  3G9G A;  4UDY X;  3O3N B;  5KBP A;  1OA0 A;  3L3P A;  3BUB A;  3I04 A;  4M0M A;  2GA9 D;  2V0O A;  3DDG A;  3I01 A;  3RV1 A;  4FM3 A;  4FZO A;  3T49 A;  4HY9 A;  4NQI A;  3BVV A;  2WYI A;  4EZQ A;  1OA1 A;  4JWD A;  4NSW A;  3RV0 A;  4EZT A;  3D50 A;  3HAI A;  4PO2 A;  4G6Q A;  3DPQ A;  4ATM A;  3QE6 A;  2RT6 A;  2Z0V A;  3VEA A;  1I4L A;  2X3X A;  4IM0 A;  3DX1 A;  1I49 A;  4FZS A;  5FIG A;  4EZN A;  3GI7 A;  4EZP A;  2Z0N A;  3KAV A;  1PS3 A;  2C08 A;  4H6H A;  3D51 A;  2X5C A;  3VKH A;  2Z0O A;  2RAI A;  1HXK A;  4AZH A;  4WPE A;  4HYB A;  3DDF A;  2OO2 A;  1E9V A;  2F7Q A;  1I4D A;  3BUD A;  4AZB A;  2O0I 1;  1O7D B;  3M3W A;  5TKY A;  3DPP A;  4H6I A;  4NPH A;  3B52 X;  1TQV A;  4EZS A;  3HAH A;  2YIB A;  2F1A A;  1I4T A;  1TQT A;  3ZED A;  4AZG A;  2PY6 A;  1SU7 A;  4AZC B;  2RAJ A;  1SU6 A;  3QNI A;  3DX2 A;  1DKZ A;  3DPO A;  4AZ5 A;  3QNJ A;  1TQW A;  2FYV A;  3O3M B;  2LXY A;  4EZZ A;  1W9M A;  4JNE A;  2Q13 A;  3T48 A;  3QA8 A;  2F7P A;  3D52 A;  2F7O A;  4AZ7 A;  4F01 A;  4EZV A;  1GNT A;  5FLE X;  2F1B A;  3KAW A;  4IWQ A;  1JQK A;  3EJR A;  3EJU A;  2YL9 A;  4DYL A;  2LM0 A;  2Z8Y A;  1DKY A;  1UPX A;  1HWW A;  4JN4 A;  3O3O B;  2NCZ A;  3DX0 A;  4JLC A;  1ZWW A;  3ACO A;  4R5I A;  4R5G A;  1E1D A;  4JWC A;  3L3O M;  4HR1 B;  4KIK B;  1ZYL A;  3ER9 B;  1QWN A;  3BVW A;  2OW7 A;  1R5E A;  4H8S A;  2EFL A;  3T4A G;  2ELB A;  3ERC C;  3BLB A;  3CAZ A;  4R5K A;  2KHO A;  1GNL A;  1R33 A;  1YWM A;  4AVM A;  3ABH A;  3FD9 A;  5C5B B;  4BNE A;  4DCN C;  2D4C A;  4R5J A;  2QXL A;  1OAO A;  1SU8 A;  3C7N A;  1Y2O A;  3I2W A;  1O7D C;  2JNS A;  3UIT A;  1U00 A;  3PLT A;  4FZP A;  2EFK A;  2RAK A;  3F7W A;  3CV5 A;  2FIC A;  2YIA A;  3KDR A;  4UDX X;  4IWP A;  3A98 A;  3D4Y A;  4EZU A;  2Q12 A;  4EZY A;  2YKT A;  2F18 A;  1QWU A;  3D4Z A;  2OBM A;  4D8J A;  1LQ7 A; 
#chains in the Genus database with same CATH homology
 3I2W A;  1I4T A;  4WPE A;  3ACO A;  2X3W A;  4ATM A;  2V0O A;  4AVM A;  1X03 A;  3PLT A;  5C5B A;  3QE6 A;  2RAJ A;  2Z0N A;  2EFK A;  2RAK A;  2X3V A;  3LLL A;  4DYL A;  3QNI A;  3ABH A;  2FIC A;  3OK8 A;  2EFL A;  2Z0V A;  4H8S A;  5C5B B;  2C08 A;  4NQI A;  1I4D A;  4BNE A;  2D1L A;  4DCN C;  3G9G A;  1I4L A;  3Q84 A;  4I1Q A;  3DYT A;  3Q0K A;  3SYV A;  3M3W A;  1URU A;  2ELB A;  2Q12 A;  2D4C A;  2X3X A;  4NSW A;  2Z0O A;  4AKV A;  2YKT A;  3CAZ A;  1I49 A;  1WDZ A;  1X04 A;  3HAJ A;  4FZS A;  3HAI A;  2RAI A;  3SOG A;  3HAH A;  2Q13 A;  1ZWW A;  4WPC A;  3QWE A;  1Y2O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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