3I2WA

Crystal structure of efc/f-bar domain of drosophila syndapin/pacsin
Total Genus 111
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
111
sequence length
290
structure length
270
Chain Sequence
SDSFWEPGNYKRTTKRIEDGYKLCNDLQQLIQERADIEKGYAKSLRTWSKKWGELIEKGPEYGTTEAAWKGVLTESERISDVHMKIKDNLCNDVNSQIKTWQKENYHHTLMQIKERKDLEDLFKKAQKPWAKLLAKVEKAKADYHSACKTERSATHDRVQKTKDQVQKCREKYEQAIAEITKYNSVYIEDMTSVFEKCQTFEKTRLQFFKEILFNVHSCLDLTKVQSLPQIYEEFSHTINNADQQKDLKWWSNNHGINMAMNWPSFVEYT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural requirements for PACSIN/Syndapin operation during zebrafish embryonic notochord development.
pubmed doi rcsb
molecule tags Endocytosis
source organism Drosophila melanogaster
molecule keywords Syndapin
total genus 111
structure length 270
sequence length 290
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3i2wA01
3I2WA 4BNEA 2Z0NA 4NQIA 3HAIA 2C08A 3HAJA 5C5BB 1I4TA 3ABHA 5C5BA 2X3WA 2ELBA 3Q0KA 3QE6A 3QWEA 2Q13A 4H8SA 1I49A 1WDZA 4NSWA 3SYVA 3SOGA 4AKVA 3M3WA 1ZWWA 1I4LA 1X04A 2Z0VA 2RAKA 3DYTA 2Q12A 2RAJA 2X3VA 4DCNC 2FICA 3HAHA 3PLTA 2YKTA 3QNIA 1URUA 1I4DA 4AVMA 3CAZA 4WPEA 4FZSA 2D4CA 2V0OA 2EFKA 4I1QA 1Y2OA 4WPCA 3ACOA 3Q84A 2RAIA 2Z0OA 3LLLA 4ATMA 2EFLA 2X3XA 4DYLA 3G9GA 3OK8A 2D1LA 1X03A
chains in the Genus database with same CATH superfamily
3D52A 3EJUA 1I4TA 3RPMA 4PO2A 5KBPA 1O7DC 2WYIA 1DKYA 4EZTA 1I4LA 3DYTA 4EZXA 2WINM 1URUA 4AZGA 2F18A 4AZ6A 1Y2OA 4AZCA 2JNKA 1LQ7A 1GN9A 3DPPA 3BVUA 2YIVX 2F7PA 3DPQA 2Z0VA 3BUBA 3EJQA 4AVMA 4NPHA 3I01A 3RV0A 2X5CA 4R5LA 1YWMA 4FZOA 1U00A 3DPOA 1JQKA 4JLCA 4G6QA 2ZXQA 1TQWA 3CVRA 3KAVA 3O3NB 3PLTA 2YKTA 2YLLA 1R33A 3BVVA 3CZNA 3Q84A 2JNSA 2X3XA 3BVWA 3B52X 2D1LA 4BNEA 3CKDA 2C08A 2NCZA 2OW6A 1HXKA 2X3WA 2ELBA 3DX4A 4IWOA 3SYVA 4EZWA 4H6IA 2F7QA 2RT6A 4EZPA 1R34A 2Z0OA 3EJRA 3A98A 4FM3A 3B53X 1E2UA 3EJSA 3LVTA 3D51A 4FZPA 1QWUA 2YL6A 2Q12A 2FICA 1MJGA 4D8JA 2GF4A 3F7WA 3HAJA 4E81A 3ERCC 2EWFA 1W9MA 1WDZA 4NSWA 4EZZA 3VKHA 3ER9B 3OWGA 3T4AG 2X3VA 1HTYA 4IM0A 2EFKA 4WPCA 4AZCB 2ND1A 1UPXA 4DYLA 4AZ5A 3T49A 1SU7A 3ABHA 4AZBA 2OW7A 4IWPA 3M3WA 3T48A 3VEAA 2ND0A 1GNTA 3BUPA 4F00A 3CZSA 2YL5A 4JN4A 1TQTA 4EZOA 4AZHA 1O7DB 3QNJA 1ZYLA 4R5IA 3D2EA 1I49A 2MI7A 3C7NA 4EZYA 3BVTA 4HY9A 5FIGA 1TQSA 2GA9D 1TQUA 2F1BA 1SU6A 4AZ7A 1OAOA 2LM0A 4I1QA 4UDYX 3ACOA 1HWWA 4EZSA 4M0MA 4IM2A 3I2WA 2YL8A 3HAIA 2KHOA 5C5BB 4EZRA 5C5BA 3QE6A 2YI9A 4HYBA 2OO2A 3BVXA 3UITA 4FZSA 1GNLA 3DX2A 4ATMA 3O3OB 3BUDA 3G9GA 5TKYA 3GI7A 3Q0KA 4IW0A 4JWEA 3SOGA 1DKZA 2FYVA 2O0I1 4R5GA 1E1DA 4EZUA 1QX1A 3D4ZA 2F7RA 3DDGA 4E3CA 2PY6A 1TQVA 3QA8A 2YIBA 4AKVA 3KDRA 2F1AA 3BUIA 4DCNC 2YIAA 4JWCA 3QNIA 4WPEA 3DDFA 2EFLA 3B51X 1X03A 2EX3B 2ALWA 4EZQA 4IM3A 4B9QA 2YI8A 1X04A 1QWNA 2RAJA 3T46A 1E9VA 2OBLA 2GAFD 2Z8YA 3VEBA 1DKXA 2RAIA 3ZEDA 4JNEA 4NQIA 2PMRA 3QWEA 4H8SA 3CV5A 4EZNA 3DX0A 2YL9A 1PS3A 2OBMA 3BLBA 2QFFA 3O3MB 3T47A 4UDXX 3RV1A 4H6HA 4R5JA 3BUQA 3L3OM 1OA1A 4EZVA 2OZNB 5FLEX 4JWIA 4JNFA 2QKWA 3LLLA 3D4YA 3OK8A 3OHXM 2Z0NA 3EJTA 1SUFA 2YLAA 2N3KA 2RAKA 1OA0A 1SU8A 1I4DA 4KIKB 3CAZA 3D2FA 2WYHA 3LMFA 4KIKA 3DX3A 2QXLA 3ER8C 2LXYA 4JL9A 2F7OA 4R5KA 2Q13A 1ZWWA 4IWQA 3D50A 3KAWA 4F01A 3DX1A 3HAHA 3L3PA 4JWDA 2D4CA 2V0OA 3EJPA 5E84A 4AZIA 4HR1B 3FD9A 4HR1A 3I39X 1R5EA 3I04A
chains in the Genus database with same CATH topology
3I2WA 4BNEA 2Z0NA 4NQIA 3HAIA 2C08A 3HAJA 5C5BB 1I4TA 3ABHA 5C5BA 2X3WA 2ELBA 3Q0KA 3QE6A 3QWEA 2Q13A 4H8SA 1I49A 1WDZA 4NSWA 3SYVA 3SOGA 4AKVA 3M3WA 1ZWWA 1I4LA 1X04A 2Z0VA 2RAKA 3DYTA 2Q12A 2RAJA 2X3VA 4DCNC 2FICA 3HAHA 3PLTA 2YKTA 3QNIA 1URUA 1I4DA 4AVMA 3CAZA 4WPEA 4FZSA 2D4CA 2V0OA 2EFKA 4I1QA 1Y2OA 4WPCA 3ACOA 3Q84A 2RAIA 2Z0OA 3LLLA 4ATMA 2EFLA 2X3XA 4DYLA 3G9GA 3OK8A 2D1LA 1X03A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I2W A;  4BNE A;  2Z0N A;  4NQI A;  3HAI A;  2C08 A;  3HAJ A;  5C5B B;  1I4T A;  3ABH A;  5C5B A;  2X3W A;  2ELB A;  3Q0K A;  3QE6 A;  3QWE A;  2Q13 A;  4H8S A;  1I49 A;  1WDZ A;  4NSW A;  3SYV A;  3SOG A;  4AKV A;  3M3W A;  1ZWW A;  1I4L A;  1X04 A;  2Z0V A;  2RAK A;  3DYT A;  2Q12 A;  2RAJ A;  2X3V A;  4DCN C;  2FIC A;  3HAH A;  3PLT A;  2YKT A;  3QNI A;  1URU A;  1I4D A;  4AVM A;  3CAZ A;  4WPE A;  4FZS A;  2D4C A;  2V0O A;  2EFK A;  4I1Q A;  1Y2O A;  4WPC A;  3ACO A;  3Q84 A;  2RAI A;  2Z0O A;  3LLL A;  4ATM A;  2EFL A;  2X3X A;  4DYL A;  3G9G A;  3OK8 A;  2D1L A;  1X03 A; 
#chains in the Genus database with same CATH topology
 3D52 A;  3EJU A;  1I4T A;  3RPM A;  4PO2 A;  5KBP A;  1O7D C;  2WYI A;  1DKY A;  4EZT A;  1I4L A;  3DYT A;  4EZX A;  2WIN M;  1URU A;  4AZG A;  2F18 A;  4AZ6 A;  1Y2O A;  4AZC A;  2JNK A;  1LQ7 A;  1GN9 A;  3DPP A;  3BVU A;  2YIV X;  2F7P A;  3DPQ A;  2Z0V A;  3BUB A;  3EJQ A;  4AVM A;  4NPH A;  3I01 A;  3RV0 A;  2X5C A;  4R5L A;  1YWM A;  4FZO A;  1U00 A;  3DPO A;  1JQK A;  4JLC A;  4G6Q A;  2ZXQ A;  1TQW A;  3CVR A;  3KAV A;  3O3N B;  3PLT A;  2YKT A;  2YLL A;  1R33 A;  3BVV A;  3CZN A;  3Q84 A;  2JNS A;  2X3X A;  3BVW A;  3B52 X;  2D1L A;  4BNE A;  3CKD A;  2C08 A;  2NCZ A;  2OW6 A;  1HXK A;  2X3W A;  2ELB A;  3DX4 A;  4IWO A;  3SYV A;  4EZW A;  4H6I A;  2F7Q A;  2RT6 A;  4EZP A;  1R34 A;  2Z0O A;  3EJR A;  3A98 A;  4FM3 A;  3B53 X;  1E2U A;  3EJS A;  3LVT A;  3D51 A;  4FZP A;  1QWU A;  2YL6 A;  2Q12 A;  2FIC A;  1MJG A;  4D8J A;  2GF4 A;  3F7W A;  3HAJ A;  4E81 A;  3ERC C;  2EWF A;  1W9M A;  1WDZ A;  4NSW A;  4EZZ A;  3VKH A;  3ER9 B;  3OWG A;  3T4A G;  2X3V A;  1HTY A;  4IM0 A;  2EFK A;  4WPC A;  4AZC B;  2ND1 A;  1UPX A;  4DYL A;  4AZ5 A;  3T49 A;  1SU7 A;  3ABH A;  4AZB A;  2OW7 A;  4IWP A;  3M3W A;  3T48 A;  3VEA A;  2ND0 A;  1GNT A;  3BUP A;  4F00 A;  3CZS A;  2YL5 A;  4JN4 A;  1TQT A;  4EZO A;  4AZH A;  1O7D B;  3QNJ A;  1ZYL A;  4R5I A;  3D2E A;  1I49 A;  2MI7 A;  3C7N A;  4EZY A;  3BVT A;  4HY9 A;  5FIG A;  1TQS A;  2GA9 D;  1TQU A;  2F1B A;  1SU6 A;  4AZ7 A;  1OAO A;  2LM0 A;  4I1Q A;  4UDY X;  3ACO A;  1HWW A;  4EZS A;  4M0M A;  4IM2 A;  3I2W A;  2YL8 A;  3HAI A;  2KHO A;  5C5B B;  4EZR A;  5C5B A;  3QE6 A;  2YI9 A;  4HYB A;  2OO2 A;  3BVX A;  3UIT A;  4FZS A;  1GNL A;  3DX2 A;  4ATM A;  3O3O B;  3BUD A;  3G9G A;  5TKY A;  3GI7 A;  3Q0K A;  4IW0 A;  4JWE A;  3SOG A;  1DKZ A;  2FYV A;  2O0I 1;  4R5G A;  1E1D A;  4EZU A;  1QX1 A;  3D4Z A;  2F7R A;  3DDG A;  4E3C A;  2PY6 A;  1TQV A;  3QA8 A;  2YIB A;  4AKV A;  3KDR A;  2F1A A;  3BUI A;  4DCN C;  2YIA A;  4JWC A;  3QNI A;  4WPE A;  3DDF A;  2EFL A;  3B51 X;  1X03 A;  2EX3 B;  2ALW A;  4EZQ A;  4IM3 A;  4B9Q A;  2YI8 A;  1X04 A;  1QWN A;  2RAJ A;  3T46 A;  1E9V A;  2OBL A;  2GAF D;  2Z8Y A;  3VEB A;  1DKX A;  2RAI A;  3ZED A;  4JNE A;  4NQI A;  2PMR A;  3QWE A;  4H8S A;  3CV5 A;  4EZN A;  3DX0 A;  2YL9 A;  1PS3 A;  2OBM A;  3BLB A;  2QFF A;  3O3M B;  3T47 A;  4UDX X;  3RV1 A;  4H6H A;  4R5J A;  3BUQ A;  3L3O M;  1OA1 A;  4EZV A;  2OZN B;  5FLE X;  4JWI A;  4JNF A;  2QKW A;  3LLL A;  3D4Y A;  3OK8 A;  3OHX M;  2Z0N A;  3EJT A;  1SUF A;  2YLA A;  2N3K A;  2RAK A;  1OA0 A;  1SU8 A;  1I4D A;  4KIK B;  3CAZ A;  3D2F A;  2WYH A;  3LMF A;  4KIK A;  3DX3 A;  2QXL A;  3ER8 C;  2LXY A;  4JL9 A;  2F7O A;  4R5K A;  2Q13 A;  1ZWW A;  4IWQ A;  3D50 A;  3KAW A;  4F01 A;  3DX1 A;  3HAH A;  3L3P A;  4JWD A;  2D4C A;  2V0O A;  3EJP A;  5E84 A;  4AZI A;  4HR1 B;  3FD9 A;  4HR1 A;  3I39 X;  1R5E A;  3I04 A; 
#chains in the Genus database with same CATH homology
 3I2W A;  4BNE A;  2Z0N A;  4NQI A;  3HAI A;  2C08 A;  3HAJ A;  5C5B B;  1I4T A;  3ABH A;  5C5B A;  2X3W A;  2ELB A;  3Q0K A;  3QE6 A;  3QWE A;  2Q13 A;  4H8S A;  1I49 A;  1WDZ A;  4NSW A;  3SYV A;  3SOG A;  4AKV A;  3M3W A;  1ZWW A;  1I4L A;  1X04 A;  2Z0V A;  2RAK A;  3DYT A;  2Q12 A;  2RAJ A;  2X3V A;  4DCN C;  2FIC A;  3HAH A;  3PLT A;  2YKT A;  3QNI A;  1URU A;  1I4D A;  4AVM A;  3CAZ A;  4WPE A;  4FZS A;  2D4C A;  2V0O A;  2EFK A;  4I1Q A;  1Y2O A;  4WPC A;  3ACO A;  3Q84 A;  2RAI A;  2Z0O A;  3LLL A;  4ATM A;  2EFL A;  2X3X A;  4DYL A;  3G9G A;  3OK8 A;  2D1L A;  1X03 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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