3LLLA

Crystal structure of mouse pacsin2 f-bar domain
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
287
structure length
287
Chain Sequence
DSFWEVGNYKRTVKRIDDGHRLCGDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWIAVMSEAERVSELHLEVKASLMNEDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHTACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKDKYEKSLKELDQTTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVASYKTIYRELEQSIKAADAVEDLRWFRANHGPGMAMNWPQFE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A hinge in the distal end of the PACSIN 2 F-BAR domain may contribute to membrane-curvature sensing.
pubmed doi rcsb
molecule tags Endocytosis
source organism Mus musculus
molecule keywords Protein kinase C and casein kinase substrate in neurons prot
total genus 105
structure length 287
sequence length 287
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-01-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3lllA01
5C5BB 2Q13A 1I49A 1Y2OA 3G9GA 1WDZA 2EFKA 1URUA 3QE6A 4DCNC 1I4TA 4NSWA 2D4CA 3HAJA 4DYLA 3SOGA 3M3WA 3HAIA 1ZWWA 3ACOA 4AKVA 2X3WA 3Q0KA 3QWEA 4FZSA 2Z0OA 4NQIA 3ABHA 4AVMA 3LLLA 3OK8A 1X03A 2X3XA 1I4DA 3SYVA 2YKTA 3CAZA 2RAIA 1I4LA 4ATMA 4H8SA 1X04A 4BNEA 2RAJA 3Q84A 4I1QA 3I2WA 5C5BA 4WPEA 2D1LA 2EFLA 2ELBA 2Q12A 2RAKA 2X3VA 3QNIA 2FICA 2Z0NA 2C08A 3DYTA 2Z0VA 3HAHA 3PLTA 2V0OA 4WPCA
chains in the Genus database with same CATH superfamily
4EZOA 3C7NA 4IM0A 3VEAA 2QXLA 4FZOA 1QWUA 3QE6A 4FZPA 3EJSA 1DKXA 1R34A 3ACOA 2WYIA 4AZIA 3EJUA 3RV0A 4AZ5A 4ATMA 2JNKA 2OBMA 2Q12A 2EWFA 1O7DC 1HXKA 4UDYX 4KIKB 2LM0A 2EFKA 3L3OM 2KHOA 2PY6A 2ALWA 3DX1A 3M3WA 3ABHA 2GAFD 3CKDA 2RAIA 1I4LA 2YIBA 2F7RA 2EFLA 2X3VA 4JWCA 4WPCA 4HY9A 3I04A 2WINM 3EJRA 3DX2A 3GI7A 1QX1A 2GF4A 2OZNB 3ER9B 3KAVA 4EZPA 2OW6A 2FYVA 2Z0VA 4EZNA 3O3OB 3A98A 4JLCA 4IM3A 3T4AG 4NPHA 2F1AA 1TQUA 1W9MA 2YL5A 3SOGA 1ZWWA 3CZNA 1OA0A 4PO2A 4AZCA 3LLLA 3DDFA 2O0I1 1I4DA 3SYVA 2F18A 4AZCB 4EZUA 1JQKA 1R33A 2YI8A 2F7PA 3BUQA 4E81A 4JN4A 3D52A 1O7DB 4HR1A 1GNLA 4R5LA 3HAIA 4HR1B 2Z0OA 3DX0A 1X04A 1LQ7A 3QNIA 1TQWA 4JL9A 3DDGA 2F7QA 4EZQA 3BVTA 3CVRA 2ND0A 3Q0KA 3QWEA 3D50A 1ZYLA 3DPPA 5E84A 4R5KA 4JWIA 3CAZA 3BVXA 3OHXM 4H6HA 4H8SA 3B52X 1TQTA 2YLAA 4KIKA 3D4YA 1WDZA 1E1DA 3RV1A 2YI9A 3EJQA 4EZYA 2EX3B 3CV5A 3T46A 2RAKA 1GNTA 2LXYA 4IM2A 2V0OA 3T47A 5TKYA 3OWGA 3DPQA 4AZ7A 3LMFA 3D4ZA 2N3KA 3OK8A 1YWMA 1E2UA 2YKTA 4JNFA 2GA9D 2ELBA 2OW7A 2FICA 4AZBA 1OAOA 2YLLA 1DKYA 3FD9A 4JWEA 2F7OA 3BVWA 1HTYA 5FIGA 3RPMA 3ER8C 3VKHA 3BUPA 1U00A 3KAWA 1UPXA 1GN9A 4HYBA 2MI7A 3T48A 2QKWA 2Z0NA 4IW0A 5C5BB 1TQVA 2Q13A 4NSWA 3HAJA 2X5CA 3L3PA 4EZWA 3EJPA 1E9VA 4AVMA 4FZSA 3BUDA 3B53X 3D2EA 4BNEA 3O3MB 3VEBA 3Q84A 2D1LA 4R5JA 2C08A 4AZGA 4DYLA 3I39X 3BUIA 3O3NB 4DCNC 4F00A 2ND1A 4M0MA 3KDRA 2NCZA 2OO2A 1Y2OA 3G9GA 4FM3A 2F1BA 4E3CA 2ZXQA 4H6IA 3F7WA 3BVVA 4NQIA 1SU8A 1SUFA 2PMRA 3I01A 3QA8A 4IWQA 3ZEDA 2QFFA 2RAJA 4R5IA 4I1QA 3QNJA 4B9QA 4R5GA 3B51X 3CZSA 1I49A 3DX4A 3D2FA 2JNSA 1I4TA 4G6QA 3BLBA 2WYHA 1DKZA 3ERCC 3LVTA 3I2WA 3UITA 4EZZA 1PS3A 2Z8YA 3PLTA 4AZ6A 2RT6A 4IWPA 1URUA 3BVUA 2X3XA 4EZRA 2YIAA 3T49A 5C5BA 4WPEA 2YL6A 1TQSA 1SU7A 4UDXX 3DYTA 3HAHA 3EJTA 4AZHA 3DX3A 2D4CA 4JWDA 4AKVA 4D8JA 2YL8A 4EZXA 1SU6A 3DPOA 3D51A 2YIVX 4IWOA 4JNEA 5FLEX 2OBLA 1R5EA 3BUBA 4EZVA 1MJGA 2X3WA 4EZSA 1HWWA 4EZTA 5KBPA 1X03A 2YL9A 1QWNA 1OA1A 4F01A
chains in the Genus database with same CATH topology
5C5BB 2Q13A 1I49A 1Y2OA 3G9GA 1WDZA 2EFKA 1URUA 3QE6A 4DCNC 1I4TA 4NSWA 2D4CA 3HAJA 4DYLA 3SOGA 3M3WA 3HAIA 1ZWWA 3ACOA 4AKVA 2X3WA 3Q0KA 3QWEA 4FZSA 2Z0OA 4NQIA 3ABHA 4AVMA 3LLLA 3OK8A 1X03A 2X3XA 1I4DA 3SYVA 2YKTA 3CAZA 2RAIA 1I4LA 4ATMA 4H8SA 1X04A 4BNEA 2RAJA 3Q84A 4I1QA 3I2WA 5C5BA 4WPEA 2D1LA 2EFLA 2ELBA 2Q12A 2RAKA 2X3VA 3QNIA 2FICA 2Z0NA 2C08A 3DYTA 2Z0VA 3HAHA 3PLTA 2V0OA 4WPCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5C5B B;  2Q13 A;  1I49 A;  1Y2O A;  3G9G A;  1WDZ A;  2EFK A;  1URU A;  3QE6 A;  4DCN C;  1I4T A;  4NSW A;  2D4C A;  3HAJ A;  4DYL A;  3SOG A;  3M3W A;  3HAI A;  1ZWW A;  3ACO A;  4AKV A;  2X3W A;  3Q0K A;  3QWE A;  4FZS A;  2Z0O A;  4NQI A;  3ABH A;  4AVM A;  3LLL A;  3OK8 A;  1X03 A;  2X3X A;  1I4D A;  3SYV A;  2YKT A;  3CAZ A;  2RAI A;  1I4L A;  4ATM A;  4H8S A;  1X04 A;  4BNE A;  2RAJ A;  3Q84 A;  4I1Q A;  3I2W A;  5C5B A;  4WPE A;  2D1L A;  2EFL A;  2ELB A;  2Q12 A;  2RAK A;  2X3V A;  3QNI A;  2FIC A;  2Z0N A;  2C08 A;  3DYT A;  2Z0V A;  3HAH A;  3PLT A;  2V0O A;  4WPC A; 
#chains in the Genus database with same CATH topology
 4EZO A;  3C7N A;  4IM0 A;  3VEA A;  2QXL A;  4FZO A;  1QWU A;  3QE6 A;  4FZP A;  3EJS A;  1DKX A;  1R34 A;  3ACO A;  2WYI A;  4AZI A;  3EJU A;  3RV0 A;  4AZ5 A;  4ATM A;  2JNK A;  2OBM A;  2Q12 A;  2EWF A;  1O7D C;  1HXK A;  4UDY X;  4KIK B;  2LM0 A;  2EFK A;  3L3O M;  2KHO A;  2PY6 A;  2ALW A;  3DX1 A;  3M3W A;  3ABH A;  2GAF D;  3CKD A;  2RAI A;  1I4L A;  2YIB A;  2F7R A;  2EFL A;  2X3V A;  4JWC A;  4WPC A;  4HY9 A;  3I04 A;  2WIN M;  3EJR A;  3DX2 A;  3GI7 A;  1QX1 A;  2GF4 A;  2OZN B;  3ER9 B;  3KAV A;  4EZP A;  2OW6 A;  2FYV A;  2Z0V A;  4EZN A;  3O3O B;  3A98 A;  4JLC A;  4IM3 A;  3T4A G;  4NPH A;  2F1A A;  1TQU A;  1W9M A;  2YL5 A;  3SOG A;  1ZWW A;  3CZN A;  1OA0 A;  4PO2 A;  4AZC A;  3LLL A;  3DDF A;  2O0I 1;  1I4D A;  3SYV A;  2F18 A;  4AZC B;  4EZU A;  1JQK A;  1R33 A;  2YI8 A;  2F7P A;  3BUQ A;  4E81 A;  4JN4 A;  3D52 A;  1O7D B;  4HR1 A;  1GNL A;  4R5L A;  3HAI A;  4HR1 B;  2Z0O A;  3DX0 A;  1X04 A;  1LQ7 A;  3QNI A;  1TQW A;  4JL9 A;  3DDG A;  2F7Q A;  4EZQ A;  3BVT A;  3CVR A;  2ND0 A;  3Q0K A;  3QWE A;  3D50 A;  1ZYL A;  3DPP A;  5E84 A;  4R5K A;  4JWI A;  3CAZ A;  3BVX A;  3OHX M;  4H6H A;  4H8S A;  3B52 X;  1TQT A;  2YLA A;  4KIK A;  3D4Y A;  1WDZ A;  1E1D A;  3RV1 A;  2YI9 A;  3EJQ A;  4EZY A;  2EX3 B;  3CV5 A;  3T46 A;  2RAK A;  1GNT A;  2LXY A;  4IM2 A;  2V0O A;  3T47 A;  5TKY A;  3OWG A;  3DPQ A;  4AZ7 A;  3LMF A;  3D4Z A;  2N3K A;  3OK8 A;  1YWM A;  1E2U A;  2YKT A;  4JNF A;  2GA9 D;  2ELB A;  2OW7 A;  2FIC A;  4AZB A;  1OAO A;  2YLL A;  1DKY A;  3FD9 A;  4JWE A;  2F7O A;  3BVW A;  1HTY A;  5FIG A;  3RPM A;  3ER8 C;  3VKH A;  3BUP A;  1U00 A;  3KAW A;  1UPX A;  1GN9 A;  4HYB A;  2MI7 A;  3T48 A;  2QKW A;  2Z0N A;  4IW0 A;  5C5B B;  1TQV A;  2Q13 A;  4NSW A;  3HAJ A;  2X5C A;  3L3P A;  4EZW A;  3EJP A;  1E9V A;  4AVM A;  4FZS A;  3BUD A;  3B53 X;  3D2E A;  4BNE A;  3O3M B;  3VEB A;  3Q84 A;  2D1L A;  4R5J A;  2C08 A;  4AZG A;  4DYL A;  3I39 X;  3BUI A;  3O3N B;  4DCN C;  4F00 A;  2ND1 A;  4M0M A;  3KDR A;  2NCZ A;  2OO2 A;  1Y2O A;  3G9G A;  4FM3 A;  2F1B A;  4E3C A;  2ZXQ A;  4H6I A;  3F7W A;  3BVV A;  4NQI A;  1SU8 A;  1SUF A;  2PMR A;  3I01 A;  3QA8 A;  4IWQ A;  3ZED A;  2QFF A;  2RAJ A;  4R5I A;  4I1Q A;  3QNJ A;  4B9Q A;  4R5G A;  3B51 X;  3CZS A;  1I49 A;  3DX4 A;  3D2F A;  2JNS A;  1I4T A;  4G6Q A;  3BLB A;  2WYH A;  1DKZ A;  3ERC C;  3LVT A;  3I2W A;  3UIT A;  4EZZ A;  1PS3 A;  2Z8Y A;  3PLT A;  4AZ6 A;  2RT6 A;  4IWP A;  1URU A;  3BVU A;  2X3X A;  4EZR A;  2YIA A;  3T49 A;  5C5B A;  4WPE A;  2YL6 A;  1TQS A;  1SU7 A;  4UDX X;  3DYT A;  3HAH A;  3EJT A;  4AZH A;  3DX3 A;  2D4C A;  4JWD A;  4AKV A;  4D8J A;  2YL8 A;  4EZX A;  1SU6 A;  3DPO A;  3D51 A;  2YIV X;  4IWO A;  4JNE A;  5FLE X;  2OBL A;  1R5E A;  3BUB A;  4EZV A;  1MJG A;  2X3W A;  4EZS A;  1HWW A;  4EZT A;  5KBP A;  1X03 A;  2YL9 A;  1QWN A;  1OA1 A;  4F01 A; 
#chains in the Genus database with same CATH homology
 5C5B B;  2Q13 A;  1I49 A;  1Y2O A;  3G9G A;  1WDZ A;  2EFK A;  1URU A;  3QE6 A;  4DCN C;  1I4T A;  4NSW A;  2D4C A;  3HAJ A;  4DYL A;  3SOG A;  3M3W A;  3HAI A;  1ZWW A;  3ACO A;  4AKV A;  2X3W A;  3Q0K A;  3QWE A;  4FZS A;  2Z0O A;  4NQI A;  3ABH A;  4AVM A;  3LLL A;  3OK8 A;  1X03 A;  2X3X A;  1I4D A;  3SYV A;  2YKT A;  3CAZ A;  2RAI A;  1I4L A;  4ATM A;  4H8S A;  1X04 A;  4BNE A;  2RAJ A;  3Q84 A;  4I1Q A;  3I2W A;  5C5B A;  4WPE A;  2D1L A;  2EFL A;  2ELB A;  2Q12 A;  2RAK A;  2X3V A;  3QNI A;  2FIC A;  2Z0N A;  2C08 A;  3DYT A;  2Z0V A;  3HAH A;  3PLT A;  2V0O A;  4WPC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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