3M3WA

Crystal strcuture of mouse pacsin3 bar domain mutant
Total Genus 112
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
288
structure length
280
Chain Sequence
GSFWEAGNYRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLADWARKWRGAVEKGPQYGTLEKAWHAFFTAAERLSELHLEVREKLHGPDSERVRTWQRGAFHGFRASRAAEDGFRKAQKPWLKRLKEVEASKKSYHTARKDEKTAQTRESHAKADSSMQLRKLQERVGRCTKEAEKMKTQYEQTLAELNRYTPRYMEDMEQAFESCQAAERQRLLFFKDVLLTLHQHLDLSSSDKFHELHRDLQQSIEAASDEEDLRWWRSTHGPGMAMNWPQFEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Rigidity of wedge loop in PACSIN 3 protein is a key factor in dictating diameters of tubules
pubmed doi rcsb
molecule tags Endocytosis
source organism Mus musculus
molecule keywords Protein kinase C and casein kinase II substrate protein 3
total genus 112
structure length 280
sequence length 288
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-03-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3m3wA01
2RAKA 2D4CA 1Y2OA 2Z0NA 4NQIA 2Z0VA 3G9GA 3PLTA 1X03A 2Q13A 3SOGA 2X3VA 3ABHA 1I49A 1I4DA 2Z0OA 3Q0KA 1X04A 3HAIA 3QWEA 4BNEA 2D1LA 5C5BA 1WDZA 2EFKA 2Q12A 3DYTA 3Q84A 4I1QA 5C5BB 3QE6A 2EFLA 2YKTA 3I2WA 4DYLA 3M3WA 1I4LA 3HAJA 3OK8A 1URUA 4AVMA 4ATMA 3SYVA 3HAHA 4AKVA 2C08A 2FICA 2RAIA 3ACOA 3QNIA 4FZSA 2X3XA 4H8SA 1ZWWA 2RAJA 3CAZA 4WPCA 3LLLA 4DCNC 2V0OA 4WPEA 4NSWA 1I4TA 2ELBA 2X3WA
chains in the Genus database with same CATH superfamily
2NCZA 1TQWA 1X03A 4FZPA 5E84A 2X3VA 3BUQA 4F00A 4PO2A 3GI7A 2YIVX 2QKWA 2WYIA 2OW6A 4FZSA 3KAWA 3CAZA 4WPCA 3BVTA 4NPHA 4JWEA 4EZOA 2EX3B 3Q0KA 3D4YA 4EZUA 4HY9A 3M3WA 4B9QA 4EZZA 5FLEX 2N3KA 1ZWWA 3LLLA 2KHOA 2WYHA 4EZWA 2PY6A 1SU8A 1ZYLA 5C5BA 2YL5A 4JNFA 3I2WA 3O3OB 2F7QA 4EZNA 1I4TA 2QFFA 2YL9A 4HR1A 3BVUA 3DYTA 2OZNB 1O7DB 4AZCB 2YI9A 2OBLA 3D50A 3Q84A 2X3WA 3RPMA 3OWGA 3QA8A 3PLTA 4AZHA 5FIGA 4UDYX 4UDXX 2FYVA 3DX0A 3QE6A 2JNSA 2YKTA 3I39X 2QXLA 3CZNA 4FM3A 3CVRA 3SYVA 2YIBA 4EZYA 1O7DC 3LVTA 1Y2OA 1R33A 5TKYA 2RT6A 3D51A 4AZGA 4IM0A 1W9MA 3B51X 4AZ7A 4E81A 4EZQA 1GN9A 4AZBA 4HYBA 3DX2A 4ATMA 4E3CA 3UITA 3D4ZA 4NQIA 1LQ7A 2YL8A 4IWQA 5KBPA 4JWCA 4IW0A 1SU6A 4M0MA 3RV0A 4I1QA 3DPOA 4FZOA 4DYLA 4EZSA 3CKDA 3EJUA 2ND0A 4H6IA 3DX4A 2OW7A 3T49A 2ELBA 2PMRA 2RAKA 2Z0VA 4KIKB 3VEAA 3VEBA 3BUIA 3KDRA 2GAFD 4D8JA 2LXYA 3EJPA 1HTYA 4R5IA 4JLCA 2WINM 4AKVA 2GF4A 1SUFA 2X3XA 3T48A 3DPPA 3VKHA 3ERCC 4JN4A 4AZ6A 3B53X 3B52X 3OHXM 2GA9D 2F1AA 1HWWA 2EWFA 3FD9A 3D52A 2RAIA 3EJRA 1R5EA 3O3MB 1DKXA 4JNEA 3T4AG 2OBMA 3DPQA 1U00A 2F7PA 3BLBA 3KAVA 4R5JA 1I4LA 3OK8A 3D2FA 3HAHA 3I04A 4DCNC 3D2EA 1QWNA 2D4CA 4IWOA 1E9VA 3DX1A 2ND1A 3BVWA 3C7NA 2Z0OA 2YL6A 1QWUA 1GNLA 1DKYA 3BUPA 1URUA 2F7OA 3CV5A 1OAOA 4WPEA 3I01A 1OA1A 2Z0NA 3G9GA 3L3PA 4H6HA 4JWIA 1R34A 1MJGA 4BNEA 1X04A 3L3OM 3DDGA 3EJSA 3LMFA 5C5BB 2YIAA 3ER8C 2O0I1 2F7RA 3A98A 2X5CA 3T47A 1HXKA 3ACOA 4IM2A 2LM0A 4EZXA 3BVVA 1E1DA 3ABHA 1I49A 3HAIA 4R5GA 2EFKA 4HR1B 4R5KA 2EFLA 2F1BA 4R5LA 3EJTA 1TQUA 4AVMA 2ALWA 4F01A 3O3NB 4EZVA 3QNIA 2MI7A 4G6QA 1DKZA 1TQTA 2JNKA 1E2UA 3DX3A 3DDFA 2Q13A 3F7WA 3ZEDA 3BVXA 4EZTA 2D1LA 2Z8YA 1TQVA 3RV1A 1GNTA 4IM3A 2FICA 3ER9B 3BUBA 4KIKA 1OA0A 3BUDA 1YWMA 4JWDA 1PS3A 3HAJA 3CZSA 3EJQA 1TQSA 2C08A 1SU7A 4H8SA 1QX1A 2RAJA 3T46A 2OO2A 2YLAA 4JL9A 4EZRA 2F18A 3SOGA 1UPXA 3QNJA 1I4DA 3QWEA 4EZPA 1WDZA 2Q12A 2YLLA 4AZCA 4AZIA 4AZ5A 2ZXQA 1JQKA 2V0OA 4NSWA 2YI8A 4IWPA
chains in the Genus database with same CATH topology
2RAKA 2D4CA 1Y2OA 2Z0NA 4NQIA 2Z0VA 3G9GA 3PLTA 1X03A 2Q13A 3SOGA 2X3VA 3ABHA 1I49A 1I4DA 2Z0OA 3Q0KA 1X04A 3HAIA 3QWEA 4BNEA 2D1LA 5C5BA 1WDZA 2EFKA 2Q12A 3DYTA 3Q84A 4I1QA 5C5BB 3QE6A 2EFLA 2YKTA 3I2WA 4DYLA 3M3WA 1I4LA 3HAJA 3OK8A 1URUA 4AVMA 4ATMA 3SYVA 3HAHA 4AKVA 2C08A 2FICA 2RAIA 3ACOA 3QNIA 4FZSA 2X3XA 4H8SA 1ZWWA 2RAJA 3CAZA 4WPCA 3LLLA 4DCNC 2V0OA 4WPEA 4NSWA 1I4TA 2ELBA 2X3WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RAK A;  2D4C A;  1Y2O A;  2Z0N A;  4NQI A;  2Z0V A;  3G9G A;  3PLT A;  1X03 A;  2Q13 A;  3SOG A;  2X3V A;  3ABH A;  1I49 A;  1I4D A;  2Z0O A;  3Q0K A;  1X04 A;  3HAI A;  3QWE A;  4BNE A;  2D1L A;  5C5B A;  1WDZ A;  2EFK A;  2Q12 A;  3DYT A;  3Q84 A;  4I1Q A;  5C5B B;  3QE6 A;  2EFL A;  2YKT A;  3I2W A;  4DYL A;  3M3W A;  1I4L A;  3HAJ A;  3OK8 A;  1URU A;  4AVM A;  4ATM A;  3SYV A;  3HAH A;  4AKV A;  2C08 A;  2FIC A;  2RAI A;  3ACO A;  3QNI A;  4FZS A;  2X3X A;  4H8S A;  1ZWW A;  2RAJ A;  3CAZ A;  4WPC A;  3LLL A;  4DCN C;  2V0O A;  4WPE A;  4NSW A;  1I4T A;  2ELB A;  2X3W A; 
#chains in the Genus database with same CATH topology
 2NCZ A;  1TQW A;  1X03 A;  4FZP A;  5E84 A;  2X3V A;  3BUQ A;  4F00 A;  4PO2 A;  3GI7 A;  2YIV X;  2QKW A;  2WYI A;  2OW6 A;  4FZS A;  3KAW A;  3CAZ A;  4WPC A;  3BVT A;  4NPH A;  4JWE A;  4EZO A;  2EX3 B;  3Q0K A;  3D4Y A;  4EZU A;  4HY9 A;  3M3W A;  4B9Q A;  4EZZ A;  5FLE X;  2N3K A;  1ZWW A;  3LLL A;  2KHO A;  2WYH A;  4EZW A;  2PY6 A;  1SU8 A;  1ZYL A;  5C5B A;  2YL5 A;  4JNF A;  3I2W A;  3O3O B;  2F7Q A;  4EZN A;  1I4T A;  2QFF A;  2YL9 A;  4HR1 A;  3BVU A;  3DYT A;  2OZN B;  1O7D B;  4AZC B;  2YI9 A;  2OBL A;  3D50 A;  3Q84 A;  2X3W A;  3RPM A;  3OWG A;  3QA8 A;  3PLT A;  4AZH A;  5FIG A;  4UDY X;  4UDX X;  2FYV A;  3DX0 A;  3QE6 A;  2JNS A;  2YKT A;  3I39 X;  2QXL A;  3CZN A;  4FM3 A;  3CVR A;  3SYV A;  2YIB A;  4EZY A;  1O7D C;  3LVT A;  1Y2O A;  1R33 A;  5TKY A;  2RT6 A;  3D51 A;  4AZG A;  4IM0 A;  1W9M A;  3B51 X;  4AZ7 A;  4E81 A;  4EZQ A;  1GN9 A;  4AZB A;  4HYB A;  3DX2 A;  4ATM A;  4E3C A;  3UIT A;  3D4Z A;  4NQI A;  1LQ7 A;  2YL8 A;  4IWQ A;  5KBP A;  4JWC A;  4IW0 A;  1SU6 A;  4M0M A;  3RV0 A;  4I1Q A;  3DPO A;  4FZO A;  4DYL A;  4EZS A;  3CKD A;  3EJU A;  2ND0 A;  4H6I A;  3DX4 A;  2OW7 A;  3T49 A;  2ELB A;  2PMR A;  2RAK A;  2Z0V A;  4KIK B;  3VEA A;  3VEB A;  3BUI A;  3KDR A;  2GAF D;  4D8J A;  2LXY A;  3EJP A;  1HTY A;  4R5I A;  4JLC A;  2WIN M;  4AKV A;  2GF4 A;  1SUF A;  2X3X A;  3T48 A;  3DPP A;  3VKH A;  3ERC C;  4JN4 A;  4AZ6 A;  3B53 X;  3B52 X;  3OHX M;  2GA9 D;  2F1A A;  1HWW A;  2EWF A;  3FD9 A;  3D52 A;  2RAI A;  3EJR A;  1R5E A;  3O3M B;  1DKX A;  4JNE A;  3T4A G;  2OBM A;  3DPQ A;  1U00 A;  2F7P A;  3BLB A;  3KAV A;  4R5J A;  1I4L A;  3OK8 A;  3D2F A;  3HAH A;  3I04 A;  4DCN C;  3D2E A;  1QWN A;  2D4C A;  4IWO A;  1E9V A;  3DX1 A;  2ND1 A;  3BVW A;  3C7N A;  2Z0O A;  2YL6 A;  1QWU A;  1GNL A;  1DKY A;  3BUP A;  1URU A;  2F7O A;  3CV5 A;  1OAO A;  4WPE A;  3I01 A;  1OA1 A;  2Z0N A;  3G9G A;  3L3P A;  4H6H A;  4JWI A;  1R34 A;  1MJG A;  4BNE A;  1X04 A;  3L3O M;  3DDG A;  3EJS A;  3LMF A;  5C5B B;  2YIA A;  3ER8 C;  2O0I 1;  2F7R A;  3A98 A;  2X5C A;  3T47 A;  1HXK A;  3ACO A;  4IM2 A;  2LM0 A;  4EZX A;  3BVV A;  1E1D A;  3ABH A;  1I49 A;  3HAI A;  4R5G A;  2EFK A;  4HR1 B;  4R5K A;  2EFL A;  2F1B A;  4R5L A;  3EJT A;  1TQU A;  4AVM A;  2ALW A;  4F01 A;  3O3N B;  4EZV A;  3QNI A;  2MI7 A;  4G6Q A;  1DKZ A;  1TQT A;  2JNK A;  1E2U A;  3DX3 A;  3DDF A;  2Q13 A;  3F7W A;  3ZED A;  3BVX A;  4EZT A;  2D1L A;  2Z8Y A;  1TQV A;  3RV1 A;  1GNT A;  4IM3 A;  2FIC A;  3ER9 B;  3BUB A;  4KIK A;  1OA0 A;  3BUD A;  1YWM A;  4JWD A;  1PS3 A;  3HAJ A;  3CZS A;  3EJQ A;  1TQS A;  2C08 A;  1SU7 A;  4H8S A;  1QX1 A;  2RAJ A;  3T46 A;  2OO2 A;  2YLA A;  4JL9 A;  4EZR A;  2F18 A;  3SOG A;  1UPX A;  3QNJ A;  1I4D A;  3QWE A;  4EZP A;  1WDZ A;  2Q12 A;  2YLL A;  4AZC A;  4AZI A;  4AZ5 A;  2ZXQ A;  1JQK A;  2V0O A;  4NSW A;  2YI8 A;  4IWP A; 
#chains in the Genus database with same CATH homology
 2RAK A;  2D4C A;  1Y2O A;  2Z0N A;  4NQI A;  2Z0V A;  3G9G A;  3PLT A;  1X03 A;  2Q13 A;  3SOG A;  2X3V A;  3ABH A;  1I49 A;  1I4D A;  2Z0O A;  3Q0K A;  1X04 A;  3HAI A;  3QWE A;  4BNE A;  2D1L A;  5C5B A;  1WDZ A;  2EFK A;  2Q12 A;  3DYT A;  3Q84 A;  4I1Q A;  5C5B B;  3QE6 A;  2EFL A;  2YKT A;  3I2W A;  4DYL A;  3M3W A;  1I4L A;  3HAJ A;  3OK8 A;  1URU A;  4AVM A;  4ATM A;  3SYV A;  3HAH A;  4AKV A;  2C08 A;  2FIC A;  2RAI A;  3ACO A;  3QNI A;  4FZS A;  2X3X A;  4H8S A;  1ZWW A;  2RAJ A;  3CAZ A;  4WPC A;  3LLL A;  4DCN C;  2V0O A;  4WPE A;  4NSW A;  1I4T A;  2ELB A;  2X3W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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