3Q0KA

Crystal structure of human pacsin 2 f-bar
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
289
structure length
287
Chain Sequence
DSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKAPSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQEEW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of human PACSIN 2 F-BAR domain
rcsb
molecule tags Endocytosis
source organism Homo sapiens
molecule keywords Protein kinase C and casein kinase substrate in neurons prot
total genus 113
structure length 287
sequence length 289
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2010-12-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3q0kA01
1I4LA 1ZWWA 3HAHA 3LLLA 2EFLA 2X3XA 2V0OA 3Q84A 4AKVA 3CAZA 2RAJA 1X03A 1I49A 3G9GA 5C5BA 3OK8A 2Z0NA 2Z0VA 4AVMA 2D4CA 4BNEA 3M3WA 3I2WA 5C5BB 2EFKA 2Q13A 4NQIA 4ATMA 1X04A 2C08A 2FICA 3DYTA 3ACOA 3HAIA 2Q12A 2Z0OA 3PLTA 1WDZA 2RAKA 4I1QA 3SYVA 3QE6A 2X3VA 3QNIA 4WPCA 4DCNC 4DYLA 3HAJA 1I4DA 2YKTA 1Y2OA 3Q0KA 1I4TA 3SOGA 2ELBA 4NSWA 4H8SA 3ABHA 2X3WA 4WPEA 1URUA 2RAIA 2D1LA 3QWEA 4FZSA
chains in the Genus database with same CATH superfamily
3D50A 4AZIA 2YIVX 2ND1A 1I49A 1R34A 4AVMA 2EFKA 4EZNA 1TQWA 2LM0A 4JNEA 3QNIA 2F7PA 4M0MA 4EZOA 1YWMA 3T46A 1TQTA 1GN9A 1DKZA 2YL9A 4EZYA 1OA0A 1R33A 4JLCA 5C5BA 3KAWA 2D4CA 3DPQA 2F7RA 1DKYA 2O0I1 4EZQA 1DKXA 4FZOA 3HAJA 2WINM 1HXKA 3ABHA 3BUBA 3D2EA 2OBMA 4R5IA 3A98A 2GF4A 3B52X 3O3OB 2F18A 4NQIA 4ATMA 3ACOA 4HR1A 3UITA 2YI9A 4JNFA 3RV1A 3OHXM 3D51A 2X3WA 4KIKB 3T4AG 2MI7A 2EFLA 3G9GA 4JWCA 3L3PA 4EZZA 3I2WA 3L3OM 3ER8C 2C08A 4AZCB 3O3NB 4R5LA 2RAKA 3VKHA 3F7WA 2YKTA 4H8SA 2JNKA 3CKDA 2YLLA 3QA8A 3T49A 3DPOA 5FIGA 2YIBA 2YI8A 4EZRA 1JQKA 1ZYLA 3M3WA 1E9VA 4HYBA 3BUPA 2X3VA 3BVTA 4UDXX 2PY6A 3SOGA 1ZWWA 3Q84A 4EZPA 4EZTA 4AZ6A 1PS3A 3D2FA 3DYTA 4JWEA 2FYVA 3DX1A 3BVXA 1SU8A 1OAOA 4KIKA 3ERCC 4EZUA 2Z8YA 1R5EA 4NPHA 3VEBA 4EZXA 4AZCA 2ZXQA 1E1DA 1E2UA 3EJTA 2Z0OA 2OO2A 3DDFA 1I4TA 4IWQA 2ELBA 3D52A 2YLAA 3O3MB 2ND0A 3HAHA 1O7DC 4F01A 1TQVA 1HWWA 1X03A 3EJSA 4JN4A 4F00A 1O7DB 2RT6A 1SUFA 4JWIA 3EJPA 3I01A 2WYHA 3EJUA 4WPCA 3DDGA 3LLLA 3D4ZA 3LMFA 4IM3A 2QKWA 3PLTA 3DX0A 2NCZA 3FD9A 4IWPA 3C7NA 3QWEA 4UDYX 1I4LA 4AKVA 2OBLA 3DX2A 3DX3A 5KBPA 4EZVA 1UPXA 5TKYA 3LVTA 2OW7A 3D4YA 3OWGA 4JL9A 4DCNC 3Q0KA 3BVWA 1URUA 4H6IA 3DX4A 4AZHA 2JNSA 2YL8A 3BUQA 3CAZA 2RAJA 1QWUA 1OA1A 3CZNA 1W9MA 2Q13A 2GAFD 4AZGA 4G6QA 4EZSA 2OZNB 4HY9A 2WYIA 3BVVA 2D1LA 2X3XA 2YL6A 2EWFA 1MJGA 5FLEX 2F1BA 4FZPA 3CZSA 4E81A 2FICA 2F7QA 1QWNA 5E84A 2LXYA 1Y2OA 4NSWA 3BVUA 2EX3B 3BLBA 4AZ7A 3B51X 3OK8A 4R5JA 3ER9B 3EJRA 4D8JA 1HTYA 4AZ5A 1LQ7A 4R5KA 3SYVA 2ALWA 3T47A 2KHOA 3EJQA 1QX1A 1U00A 2RAIA 1GNTA 2GA9D 3DPPA 2F1AA 3BUIA 3CVRA 2Z0NA 4AZBA 1GNLA 2Q12A 2YIAA 4DYLA 3QE6A 3T48A 2N3KA 1SU7A 4JWDA 4PO2A 3VEAA 4IM0A 3GI7A 3KDRA 2OW6A 2F7OA 3B53X 4BNEA 4H6HA 5C5BB 1X04A 3I39X 3CV5A 3I04A 4R5GA 4EZWA 4IW0A 1WDZA 2X5CA 4I1QA 4E3CA 2QXLA 4IM2A 2YL5A 4FZSA 4WPEA 2V0OA 4B9QA 3RV0A 4FM3A 2Z0VA 3KAVA 3ZEDA 1TQSA 3HAIA 1SU6A 1TQUA 4HR1B 2PMRA 3BUDA 1I4DA 2QFFA 3RPMA 3QNJA 4IWOA
chains in the Genus database with same CATH topology
1I4LA 1ZWWA 3HAHA 3LLLA 2EFLA 2X3XA 2V0OA 3Q84A 4AKVA 3CAZA 2RAJA 1X03A 1I49A 3G9GA 5C5BA 3OK8A 2Z0NA 2Z0VA 4AVMA 2D4CA 4BNEA 3M3WA 3I2WA 5C5BB 2EFKA 2Q13A 4NQIA 4ATMA 1X04A 2C08A 2FICA 3DYTA 3ACOA 3HAIA 2Q12A 2Z0OA 3PLTA 1WDZA 2RAKA 4I1QA 3SYVA 3QE6A 2X3VA 3QNIA 4WPCA 4DCNC 4DYLA 3HAJA 1I4DA 2YKTA 1Y2OA 3Q0KA 1I4TA 3SOGA 2ELBA 4NSWA 4H8SA 3ABHA 2X3WA 4WPEA 1URUA 2RAIA 2D1LA 3QWEA 4FZSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I4L A;  1ZWW A;  3HAH A;  3LLL A;  2EFL A;  2X3X A;  2V0O A;  3Q84 A;  4AKV A;  3CAZ A;  2RAJ A;  1X03 A;  1I49 A;  3G9G A;  5C5B A;  3OK8 A;  2Z0N A;  2Z0V A;  4AVM A;  2D4C A;  4BNE A;  3M3W A;  3I2W A;  5C5B B;  2EFK A;  2Q13 A;  4NQI A;  4ATM A;  1X04 A;  2C08 A;  2FIC A;  3DYT A;  3ACO A;  3HAI A;  2Q12 A;  2Z0O A;  3PLT A;  1WDZ A;  2RAK A;  4I1Q A;  3SYV A;  3QE6 A;  2X3V A;  3QNI A;  4WPC A;  4DCN C;  4DYL A;  3HAJ A;  1I4D A;  2YKT A;  1Y2O A;  3Q0K A;  1I4T A;  3SOG A;  2ELB A;  4NSW A;  4H8S A;  3ABH A;  2X3W A;  4WPE A;  1URU A;  2RAI A;  2D1L A;  3QWE A;  4FZS A; 
#chains in the Genus database with same CATH topology
 3D50 A;  4AZI A;  2YIV X;  2ND1 A;  1I49 A;  1R34 A;  4AVM A;  2EFK A;  4EZN A;  1TQW A;  2LM0 A;  4JNE A;  3QNI A;  2F7P A;  4M0M A;  4EZO A;  1YWM A;  3T46 A;  1TQT A;  1GN9 A;  1DKZ A;  2YL9 A;  4EZY A;  1OA0 A;  1R33 A;  4JLC A;  5C5B A;  3KAW A;  2D4C A;  3DPQ A;  2F7R A;  1DKY A;  2O0I 1;  4EZQ A;  1DKX A;  4FZO A;  3HAJ A;  2WIN M;  1HXK A;  3ABH A;  3BUB A;  3D2E A;  2OBM A;  4R5I A;  3A98 A;  2GF4 A;  3B52 X;  3O3O B;  2F18 A;  4NQI A;  4ATM A;  3ACO A;  4HR1 A;  3UIT A;  2YI9 A;  4JNF A;  3RV1 A;  3OHX M;  3D51 A;  2X3W A;  4KIK B;  3T4A G;  2MI7 A;  2EFL A;  3G9G A;  4JWC A;  3L3P A;  4EZZ A;  3I2W A;  3L3O M;  3ER8 C;  2C08 A;  4AZC B;  3O3N B;  4R5L A;  2RAK A;  3VKH A;  3F7W A;  2YKT A;  4H8S A;  2JNK A;  3CKD A;  2YLL A;  3QA8 A;  3T49 A;  3DPO A;  5FIG A;  2YIB A;  2YI8 A;  4EZR A;  1JQK A;  1ZYL A;  3M3W A;  1E9V A;  4HYB A;  3BUP A;  2X3V A;  3BVT A;  4UDX X;  2PY6 A;  3SOG A;  1ZWW A;  3Q84 A;  4EZP A;  4EZT A;  4AZ6 A;  1PS3 A;  3D2F A;  3DYT A;  4JWE A;  2FYV A;  3DX1 A;  3BVX A;  1SU8 A;  1OAO A;  4KIK A;  3ERC C;  4EZU A;  2Z8Y A;  1R5E A;  4NPH A;  3VEB A;  4EZX A;  4AZC A;  2ZXQ A;  1E1D A;  1E2U A;  3EJT A;  2Z0O A;  2OO2 A;  3DDF A;  1I4T A;  4IWQ A;  2ELB A;  3D52 A;  2YLA A;  3O3M B;  2ND0 A;  3HAH A;  1O7D C;  4F01 A;  1TQV A;  1HWW A;  1X03 A;  3EJS A;  4JN4 A;  4F00 A;  1O7D B;  2RT6 A;  1SUF A;  4JWI A;  3EJP A;  3I01 A;  2WYH A;  3EJU A;  4WPC A;  3DDG A;  3LLL A;  3D4Z A;  3LMF A;  4IM3 A;  2QKW A;  3PLT A;  3DX0 A;  2NCZ A;  3FD9 A;  4IWP A;  3C7N A;  3QWE A;  4UDY X;  1I4L A;  4AKV A;  2OBL A;  3DX2 A;  3DX3 A;  5KBP A;  4EZV A;  1UPX A;  5TKY A;  3LVT A;  2OW7 A;  3D4Y A;  3OWG A;  4JL9 A;  4DCN C;  3Q0K A;  3BVW A;  1URU A;  4H6I A;  3DX4 A;  4AZH A;  2JNS A;  2YL8 A;  3BUQ A;  3CAZ A;  2RAJ A;  1QWU A;  1OA1 A;  3CZN A;  1W9M A;  2Q13 A;  2GAF D;  4AZG A;  4G6Q A;  4EZS A;  2OZN B;  4HY9 A;  2WYI A;  3BVV A;  2D1L A;  2X3X A;  2YL6 A;  2EWF A;  1MJG A;  5FLE X;  2F1B A;  4FZP A;  3CZS A;  4E81 A;  2FIC A;  2F7Q A;  1QWN A;  5E84 A;  2LXY A;  1Y2O A;  4NSW A;  3BVU A;  2EX3 B;  3BLB A;  4AZ7 A;  3B51 X;  3OK8 A;  4R5J A;  3ER9 B;  3EJR A;  4D8J A;  1HTY A;  4AZ5 A;  1LQ7 A;  4R5K A;  3SYV A;  2ALW A;  3T47 A;  2KHO A;  3EJQ A;  1QX1 A;  1U00 A;  2RAI A;  1GNT A;  2GA9 D;  3DPP A;  2F1A A;  3BUI A;  3CVR A;  2Z0N A;  4AZB A;  1GNL A;  2Q12 A;  2YIA A;  4DYL A;  3QE6 A;  3T48 A;  2N3K A;  1SU7 A;  4JWD A;  4PO2 A;  3VEA A;  4IM0 A;  3GI7 A;  3KDR A;  2OW6 A;  2F7O A;  3B53 X;  4BNE A;  4H6H A;  5C5B B;  1X04 A;  3I39 X;  3CV5 A;  3I04 A;  4R5G A;  4EZW A;  4IW0 A;  1WDZ A;  2X5C A;  4I1Q A;  4E3C A;  2QXL A;  4IM2 A;  2YL5 A;  4FZS A;  4WPE A;  2V0O A;  4B9Q A;  3RV0 A;  4FM3 A;  2Z0V A;  3KAV A;  3ZED A;  1TQS A;  3HAI A;  1SU6 A;  1TQU A;  4HR1 B;  2PMR A;  3BUD A;  1I4D A;  2QFF A;  3RPM A;  3QNJ A;  4IWO A; 
#chains in the Genus database with same CATH homology
 1I4L A;  1ZWW A;  3HAH A;  3LLL A;  2EFL A;  2X3X A;  2V0O A;  3Q84 A;  4AKV A;  3CAZ A;  2RAJ A;  1X03 A;  1I49 A;  3G9G A;  5C5B A;  3OK8 A;  2Z0N A;  2Z0V A;  4AVM A;  2D4C A;  4BNE A;  3M3W A;  3I2W A;  5C5B B;  2EFK A;  2Q13 A;  4NQI A;  4ATM A;  1X04 A;  2C08 A;  2FIC A;  3DYT A;  3ACO A;  3HAI A;  2Q12 A;  2Z0O A;  3PLT A;  1WDZ A;  2RAK A;  4I1Q A;  3SYV A;  3QE6 A;  2X3V A;  3QNI A;  4WPC A;  4DCN C;  4DYL A;  3HAJ A;  1I4D A;  2YKT A;  1Y2O A;  3Q0K A;  1I4T A;  3SOG A;  2ELB A;  4NSW A;  4H8S A;  3ABH A;  2X3W A;  4WPE A;  1URU A;  2RAI A;  2D1L A;  3QWE A;  4FZS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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