3Q84A

Crystal structure of human pacsin 1 f-bar domain
Total Genus 112
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
293
structure length
285
Chain Sequence
TDSFWEVGNYKRTVKRIDDGHRLCNDLMNCVQERAKIEKAYGQQLTDWAKRWRQLIEKGPQYGSLERAWGAIMTEADKVSELHQEVKNNLLNEDLEKVKNWQKDAYHKQIMGGFKETKEAEDGFRKAQKPWAKKMKELEAAKKAYHLACKEEKLAMTREMTEVPQKKLQDKVDKCKQDVQKTQEKYEKVLEDVGKTTPQYMENMEQVFEQCQQFEEKRLVFLKEVLLDIKRHLNLAENSSYIHVYRELEQAIRGADAQEDLRWFRSTSGPGMPMNWPQFEEWNPD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of human PACSIN 1 F-BAR domain
rcsb
molecule tags Endocytosis
molecule keywords Protein kinase C and casein kinase substrate in neurons prot
total genus 112
structure length 285
sequence length 293
chains with identical sequence B, G, H, M, N
ec nomenclature
pdb deposition date 2011-01-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3q84A01
2YKTA 4DCNC 2D1LA 2X3XA 3OK8A 4NSWA 1URUA 1I4DA 2RAKA 3DYTA 3PLTA 3Q84A 3LLLA 3SYVA 1I4TA 4BNEA 2D4CA 3ACOA 4WPEA 4DYLA 3HAIA 1I4LA 1I49A 1ZWWA 2Q12A 3CAZA 3I2WA 3QNIA 1X03A 4WPCA 2C08A 3HAJA 5C5BB 4AVMA 2V0OA 2Q13A 3Q0KA 4I1QA 2Z0OA 2X3WA 1Y2OA 2X3VA 2FICA 2Z0NA 2EFKA 2Z0VA 3G9GA 4NQIA 3QWEA 5C5BA 4H8SA 2ELBA 2RAIA 3SOGA 3HAHA 4AKVA 4FZSA 2EFLA 1X04A 3ABHA 3M3WA 4ATMA 3QE6A 1WDZA 2RAJA
chains in the Genus database with same CATH superfamily
1URUA 3DDFA 4UDYX 1I4TA 3RV0A 3UITA 4R5IA 2YI8A 1I4LA 3D2FA 1R5EA 2QXLA 2F1AA 4EZOA 3LMFA 1E9VA 2YLLA 4R5KA 3CZSA 3D50A 4HY9A 4EZTA 3DX4A 1E1DA 2D1LA 1YWMA 2YIAA 1I4DA 2RAKA 4BNEA 3FD9A 4JNFA 4JWDA 2Z8YA 2YI9A 5C5BB 3T48A 1QWUA 1Y2OA 2FYVA 2EWFA 4IWQA 4KIKA 3VKHA 1W9MA 3DPOA 2GA9D 3EJPA 2OW6A 3D52A 1JQKA 4IM2A 2YL8A 3CZNA 4DYLA 1TQWA 4UDXX 2WYIA 1SU7A 2Z0NA 2JNSA 5KBPA 4HR1A 4ATMA 1X04A 1GNLA 4DCNC 3I39X 2F7QA 3SYVA 4R5JA 1R34A 3VEAA 3F7WA 4FZOA 1GNTA 1U00A 3DX1A 3C7NA 2OBLA 2OW7A 4FM3A 3I01A 1OAOA 2QFFA 4E81A 3M3WA 5FLEX 2F7OA 1PS3A 3BUIA 1QX1A 2Q13A 4NQIA 1O7DC 1TQVA 2YL6A 3KDRA 3QE6A 3A98A 3LVTA 4H6HA 3PLTA 1TQSA 2RT6A 3BVUA 1HXKA 1LQ7A 1ZYLA 4D8JA 4HYBA 3T4AG 2ELBA 3ACOA 4E3CA 2ND1A 2LM0A 3HAIA 3CAZA 4EZVA 4WPCA 2V0OA 2YIBA 4EZSA 3L3OM 3OWGA 2O0I1 3DPPA 1WDZA 3T46A 2YKTA 2F1BA 2D4CA 4WPEA 2ZXQA 1X03A 4G6QA 2PMRA 1UPXA 4IW0A 2YL9A 5E84A 4PO2A 4F01A 4EZWA 3SOGA 3DPQA 4FZSA 3RPMA 4JWCA 3GI7A 4I1QA 2JNKA 3EJQA 2N3KA 3OK8A 3O3MB 3BVVA 3DYTA 1QWNA 2YL5A 1I49A 2YIVX 2KHOA 3L3PA 2GF4A 1SU6A 2Z0VA 3I04A 1HWWA 1R33A 1DKZA 3Q84A 4FZPA 3KAVA 2OZNB 4JNEA 4AZGA 3QNIA 2YLAA 4EZUA 3B53X 3D4ZA 3BVTA 2X3VA 4AZIA 2EFKA 3BUPA 3VEBA 3T47A 4EZQA 2F18A 3D4YA 2RAJA 4EZRA 4AZCB 4F00A 3B51X 3BLBA 3EJSA 3I2WA 1DKYA 3EJUA 4JWIA 2X3WA 3D51A 3EJTA 2FICA 4H8SA 1OA1A 2F7RA 1E2UA 2PY6A 3ER9B 1O7DB 4EZPA 4H6IA 4M0MA 4R5GA 4IWPA 3EJRA 4AZ7A 3Q0KA 4IM3A 1SUFA 4JWEA 3BUBA 3HAHA 2EFLA 3ABHA 2MI7A 1TQTA 4JL9A 3ERCC 2EX3B 4AZ5A 3LLLA 2LXYA 1DKXA 2NCZA 3BVWA 3CVRA 4R5LA 2OBMA 3QNJA 2Z0OA 4JN4A 3DX3A 3O3NB 4IWOA 3DX0A 2QKWA 5FIGA 4JLCA 1OA0A 2ALWA 3D2EA 3BUQA 4B9QA 3BUDA 4AZCA 3QA8A 3B52X 3DX2A 2GAFD 2RAIA 3OHXM 2X5CA 2X3XA 3CV5A 2ND0A 4AZ6A 1HTYA 1SU8A 4KIKB 1ZWWA 4IM0A 3HAJA 2F7PA 4AVMA 5TKYA 4EZNA 3G9GA 3RV1A 4EZYA 3QWEA 4EZXA 3CKDA 2WINM 3KAWA 3O3OB 3T49A 3DDGA 4NSWA 3BVXA 1GN9A 3ZEDA 4AZHA 1TQUA 2Q12A 2C08A 4HR1B 2WYHA 4AZBA 3ER8C 2OO2A 4NPHA 5C5BA 1MJGA 4AKVA 4EZZA
chains in the Genus database with same CATH topology
2YKTA 4DCNC 2D1LA 2X3XA 3OK8A 4NSWA 1URUA 1I4DA 2RAKA 3DYTA 3PLTA 3Q84A 3LLLA 3SYVA 1I4TA 4BNEA 2D4CA 3ACOA 4WPEA 4DYLA 3HAIA 1I4LA 1I49A 1ZWWA 2Q12A 3CAZA 3I2WA 3QNIA 1X03A 4WPCA 2C08A 3HAJA 5C5BB 4AVMA 2V0OA 2Q13A 3Q0KA 4I1QA 2Z0OA 2X3WA 1Y2OA 2X3VA 2FICA 2Z0NA 2EFKA 2Z0VA 3G9GA 4NQIA 3QWEA 5C5BA 4H8SA 2ELBA 2RAIA 3SOGA 3HAHA 4AKVA 4FZSA 2EFLA 1X04A 3ABHA 3M3WA 4ATMA 3QE6A 1WDZA 2RAJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YKT A;  4DCN C;  2D1L A;  2X3X A;  3OK8 A;  4NSW A;  1URU A;  1I4D A;  2RAK A;  3DYT A;  3PLT A;  3Q84 A;  3LLL A;  3SYV A;  1I4T A;  4BNE A;  2D4C A;  3ACO A;  4WPE A;  4DYL A;  3HAI A;  1I4L A;  1I49 A;  1ZWW A;  2Q12 A;  3CAZ A;  3I2W A;  3QNI A;  1X03 A;  4WPC A;  2C08 A;  3HAJ A;  5C5B B;  4AVM A;  2V0O A;  2Q13 A;  3Q0K A;  4I1Q A;  2Z0O A;  2X3W A;  1Y2O A;  2X3V A;  2FIC A;  2Z0N A;  2EFK A;  2Z0V A;  3G9G A;  4NQI A;  3QWE A;  5C5B A;  4H8S A;  2ELB A;  2RAI A;  3SOG A;  3HAH A;  4AKV A;  4FZS A;  2EFL A;  1X04 A;  3ABH A;  3M3W A;  4ATM A;  3QE6 A;  1WDZ A;  2RAJ A; 
#chains in the Genus database with same CATH topology
 1URU A;  3DDF A;  4UDY X;  1I4T A;  3RV0 A;  3UIT A;  4R5I A;  2YI8 A;  1I4L A;  3D2F A;  1R5E A;  2QXL A;  2F1A A;  4EZO A;  3LMF A;  1E9V A;  2YLL A;  4R5K A;  3CZS A;  3D50 A;  4HY9 A;  4EZT A;  3DX4 A;  1E1D A;  2D1L A;  1YWM A;  2YIA A;  1I4D A;  2RAK A;  4BNE A;  3FD9 A;  4JNF A;  4JWD A;  2Z8Y A;  2YI9 A;  5C5B B;  3T48 A;  1QWU A;  1Y2O A;  2FYV A;  2EWF A;  4IWQ A;  4KIK A;  3VKH A;  1W9M A;  3DPO A;  2GA9 D;  3EJP A;  2OW6 A;  3D52 A;  1JQK A;  4IM2 A;  2YL8 A;  3CZN A;  4DYL A;  1TQW A;  4UDX X;  2WYI A;  1SU7 A;  2Z0N A;  2JNS A;  5KBP A;  4HR1 A;  4ATM A;  1X04 A;  1GNL A;  4DCN C;  3I39 X;  2F7Q A;  3SYV A;  4R5J A;  1R34 A;  3VEA A;  3F7W A;  4FZO A;  1GNT A;  1U00 A;  3DX1 A;  3C7N A;  2OBL A;  2OW7 A;  4FM3 A;  3I01 A;  1OAO A;  2QFF A;  4E81 A;  3M3W A;  5FLE X;  2F7O A;  1PS3 A;  3BUI A;  1QX1 A;  2Q13 A;  4NQI A;  1O7D C;  1TQV A;  2YL6 A;  3KDR A;  3QE6 A;  3A98 A;  3LVT A;  4H6H A;  3PLT A;  1TQS A;  2RT6 A;  3BVU A;  1HXK A;  1LQ7 A;  1ZYL A;  4D8J A;  4HYB A;  3T4A G;  2ELB A;  3ACO A;  4E3C A;  2ND1 A;  2LM0 A;  3HAI A;  3CAZ A;  4EZV A;  4WPC A;  2V0O A;  2YIB A;  4EZS A;  3L3O M;  3OWG A;  2O0I 1;  3DPP A;  1WDZ A;  3T46 A;  2YKT A;  2F1B A;  2D4C A;  4WPE A;  2ZXQ A;  1X03 A;  4G6Q A;  2PMR A;  1UPX A;  4IW0 A;  2YL9 A;  5E84 A;  4PO2 A;  4F01 A;  4EZW A;  3SOG A;  3DPQ A;  4FZS A;  3RPM A;  4JWC A;  3GI7 A;  4I1Q A;  2JNK A;  3EJQ A;  2N3K A;  3OK8 A;  3O3M B;  3BVV A;  3DYT A;  1QWN A;  2YL5 A;  1I49 A;  2YIV X;  2KHO A;  3L3P A;  2GF4 A;  1SU6 A;  2Z0V A;  3I04 A;  1HWW A;  1R33 A;  1DKZ A;  3Q84 A;  4FZP A;  3KAV A;  2OZN B;  4JNE A;  4AZG A;  3QNI A;  2YLA A;  4EZU A;  3B53 X;  3D4Z A;  3BVT A;  2X3V A;  4AZI A;  2EFK A;  3BUP A;  3VEB A;  3T47 A;  4EZQ A;  2F18 A;  3D4Y A;  2RAJ A;  4EZR A;  4AZC B;  4F00 A;  3B51 X;  3BLB A;  3EJS A;  3I2W A;  1DKY A;  3EJU A;  4JWI A;  2X3W A;  3D51 A;  3EJT A;  2FIC A;  4H8S A;  1OA1 A;  2F7R A;  1E2U A;  2PY6 A;  3ER9 B;  1O7D B;  4EZP A;  4H6I A;  4M0M A;  4R5G A;  4IWP A;  3EJR A;  4AZ7 A;  3Q0K A;  4IM3 A;  1SUF A;  4JWE A;  3BUB A;  3HAH A;  2EFL A;  3ABH A;  2MI7 A;  1TQT A;  4JL9 A;  3ERC C;  2EX3 B;  4AZ5 A;  3LLL A;  2LXY A;  1DKX A;  2NCZ A;  3BVW A;  3CVR A;  4R5L A;  2OBM A;  3QNJ A;  2Z0O A;  4JN4 A;  3DX3 A;  3O3N B;  4IWO A;  3DX0 A;  2QKW A;  5FIG A;  4JLC A;  1OA0 A;  2ALW A;  3D2E A;  3BUQ A;  4B9Q A;  3BUD A;  4AZC A;  3QA8 A;  3B52 X;  3DX2 A;  2GAF D;  2RAI A;  3OHX M;  2X5C A;  2X3X A;  3CV5 A;  2ND0 A;  4AZ6 A;  1HTY A;  1SU8 A;  4KIK B;  1ZWW A;  4IM0 A;  3HAJ A;  2F7P A;  4AVM A;  5TKY A;  4EZN A;  3G9G A;  3RV1 A;  4EZY A;  3QWE A;  4EZX A;  3CKD A;  2WIN M;  3KAW A;  3O3O B;  3T49 A;  3DDG A;  4NSW A;  3BVX A;  1GN9 A;  3ZED A;  4AZH A;  1TQU A;  2Q12 A;  2C08 A;  4HR1 B;  2WYH A;  4AZB A;  3ER8 C;  2OO2 A;  4NPH A;  5C5B A;  1MJG A;  4AKV A;  4EZZ A; 
#chains in the Genus database with same CATH homology
 2YKT A;  4DCN C;  2D1L A;  2X3X A;  3OK8 A;  4NSW A;  1URU A;  1I4D A;  2RAK A;  3DYT A;  3PLT A;  3Q84 A;  3LLL A;  3SYV A;  1I4T A;  4BNE A;  2D4C A;  3ACO A;  4WPE A;  4DYL A;  3HAI A;  1I4L A;  1I49 A;  1ZWW A;  2Q12 A;  3CAZ A;  3I2W A;  3QNI A;  1X03 A;  4WPC A;  2C08 A;  3HAJ A;  5C5B B;  4AVM A;  2V0O A;  2Q13 A;  3Q0K A;  4I1Q A;  2Z0O A;  2X3W A;  1Y2O A;  2X3V A;  2FIC A;  2Z0N A;  2EFK A;  2Z0V A;  3G9G A;  4NQI A;  3QWE A;  5C5B A;  4H8S A;  2ELB A;  2RAI A;  3SOG A;  3HAH A;  4AKV A;  4FZS A;  2EFL A;  1X04 A;  3ABH A;  3M3W A;  4ATM A;  3QE6 A;  1WDZ A;  2RAJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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