3QWEA

Crystal structure of the n-terminal domain of the gem interacting protein
Total Genus 126
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
126
sequence length
273
structure length
260
Chain Sequence
GEELDLRLIRTKGGVDAALEYAKTWSRYAKELLAWTEKRASYELEFAKSTMKIAEAGKVSIQQQSHMPLQYIYTLFLEHDLSLGTLAMETVAQQKRDYYQPLAAKRTEIEKWRKEFKEQWMKEQKRMNEAVQALRRAQLQYVQRSEDLRARSQGSKQQERRRRSREEAQAKAQEAEALYQACVREANARQQDLEIAKQRIVSHVRKLVFQGDEVLRRVTLSLFGLRGAQAERGPRAFAALAECCAPFEPGQRYQEFVRAL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the N-terminal domain of the GEM interacting protein
rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords GEM-interacting protein
total genus 126
structure length 260
sequence length 273
ec nomenclature
pdb deposition date 2011-02-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3qweA00
2Z0OA 4WPEA 2C08A 1WDZA 2FICA 3CAZA 4NQIA 3ABHA 4I1QA 3ACOA 1I4TA 1ZWWA 1X03A 2EFLA 2ELBA 2RAJA 3HAHA 4WPCA 2YKTA 2D1LA 3OK8A 4H8SA 4DYLA 2D4CA 1X04A 2Q12A 2X3XA 2Q13A 2Z0VA 3QE6A 3Q84A 3QNIA 3I2WA 3QWEA 3HAIA 2X3VA 3SOGA 3M3WA 2RAIA 4NSWA 5C5BB 1Y2OA 2RAKA 4DCNC 3SYVA 2X3WA 3G9GA 1I4LA 4AKVA 3LLLA 1URUA 3DYTA 1I49A 2V0OA 2Z0NA 1I4DA 3PLTA 4FZSA 4AVMA 3HAJA 2EFKA 4BNEA 4ATMA 3Q0KA 5C5BA
chains in the Genus database with same CATH superfamily
2WYIA 1OA0A 3ABHA 3ACOA 1ZWWA 4EZVA 2EFLA 2OBLA 4JWIA 3I01A 5E84A 1SU7A 2Z8YA 3SOGA 3BLBA 2YIBA 1SUFA 2EFKA 5FIGA 2RT6A 4WPEA 4AZ7A 3ER8C 1QWUA 4I1QA 1TQUA 3T46A 4EZQA 3D4ZA 3LVTA 3BUDA 2F1AA 4AZCB 1SU8A 2GF4A 3QWEA 2F18A 3M3WA 3BUQA 1GNLA 3DPPA 4UDYX 2OZNB 3I04A 1U00A 1I49A 2WINM 4M0MA 4IWOA 3DX0A 3DPOA 3RV1A 2YL9A 1I4TA 1X03A 2ELBA 3CZNA 3D2FA 3L3PA 1DKYA 4AZIA 1QWNA 1TQTA 4HY9A 2QFFA 4AZCA 2OO2A 3OHXM 4EZXA 2NCZA 3LMFA 1DKZA 4JN4A 3KAWA 3RPMA 2QXLA 4EZZA 4R5LA 4H8SA 4JNFA 3Q84A 3CVRA 5FLEX 1R5EA 1GNTA 2RAIA 4PO2A 2MI7A 3BVTA 3DPQA 3DYTA 3EJTA 4EZYA 3Q0KA 4AZ5A 3D50A 2YIVX 5KBPA 1LQ7A 1E9VA 4EZSA 1R34A 2D1LA 3QA8A 4IW0A 2YIAA 3BVUA 2V0OA 3ZEDA 4FZPA 3DX2A 4JWDA 3F7WA 2RAJA 3QNJA 2O0I1 1OA1A 3C7NA 2X3WA 4AVMA 4FM3A 2YI9A 3O3MB 3DX1A 1HTYA 3FD9A 4HYBA 3O3OB 2EX3B 2PY6A 2YL6A 3ER9B 1PS3A 4EZTA 3SYVA 4JWEA 4IWPA 3VEBA 3LLLA 3HAJA 2Z0OA 3BVXA 3O3NB 2F1BA 2OW7A 1R33A 4DYLA 3ERCC 4NPHA 3B53X 3HAIA 4EZUA 4EZRA 3VEAA 2RAKA 3OWGA 4AZGA 3CV5A 2YLAA 4FZOA 4EZNA 1JQKA 3D51A 2KHOA 4R5GA 3UITA 1OAOA 2D4CA 2Q13A 3D2EA 1TQWA 3DX4A 2YL8A 1YWMA 3BUBA 3BVVA 4F00A 2N3KA 3D52A 2EWFA 3G9GA 1SU6A 1URUA 4AZBA 2YI8A 2GAFD 3PLTA 3T49A 3B51X 3CAZA 4JWCA 4NQIA 4UDXX 3T48A 4EZOA 3GI7A 2Z0VA 3QE6A 3B52X 2F7OA 1W9MA 4EZPA 2F7QA 2JNSA 3EJQA 1UPXA 1E2UA 4G6QA 4ATMA 1QX1A 1O7DB 3BVWA 2X3XA 4F01A 3QNIA 2QKWA 3CZSA 3I39X 5C5BB 4R5KA 4JLCA 4IWQA 2ZXQA 4AZHA 2F7PA 4E81A 1TQSA 2X5CA 4HR1B 2LXYA 1TQVA 4JNEA 1DKXA 3I2WA 3KAVA 3EJUA 2X3VA 1I4LA 1E1DA 2WYHA 4E3CA 4BNEA 1I4DA 3DX3A 5C5BA 1O7DC 2C08A 2YKTA 2GA9D 2LM0A 4B9QA 2F7RA 4HR1A 4AZ6A 1Y2OA 1GN9A 4IM3A 2FYVA 4R5JA 2Z0NA 3A98A 4KIKB 3BUPA 4EZWA 1HWWA 1ZYLA 3RV0A 1X04A 2Q12A 3DDFA 3KDRA 2YLLA 2YL5A 2OBMA 3EJPA 4H6IA 4H6HA 4IM2A 4FZSA 3T47A 3EJSA 2FICA 2JNKA 3HAHA 2ND1A 1HXKA 4IM0A 4KIKA 2PMRA 2OW6A 4DCNC 3EJRA 1MJGA 3BUIA 1WDZA 3L3OM 3VKHA 3D4YA 5TKYA 4WPCA 3T4AG 3DDGA 3OK8A 2ALWA 4R5IA 4NSWA 2ND0A 4AKVA 4D8JA 4JL9A 3CKDA
chains in the Genus database with same CATH topology
2Z0OA 4WPEA 2C08A 1WDZA 2FICA 3CAZA 4NQIA 3ABHA 4I1QA 3ACOA 1I4TA 1ZWWA 1X03A 2EFLA 2ELBA 2RAJA 3HAHA 4WPCA 2YKTA 2D1LA 3OK8A 4H8SA 4DYLA 2D4CA 1X04A 2Q12A 2X3XA 2Q13A 2Z0VA 3QE6A 3Q84A 3QNIA 3I2WA 3QWEA 3HAIA 2X3VA 3SOGA 3M3WA 2RAIA 4NSWA 5C5BB 1Y2OA 2RAKA 4DCNC 3SYVA 2X3WA 3G9GA 1I4LA 4AKVA 3LLLA 1URUA 3DYTA 1I49A 2V0OA 2Z0NA 1I4DA 3PLTA 4FZSA 4AVMA 3HAJA 2EFKA 4BNEA 4ATMA 3Q0KA 5C5BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Z0O A;  4WPE A;  2C08 A;  1WDZ A;  2FIC A;  3CAZ A;  4NQI A;  3ABH A;  4I1Q A;  3ACO A;  1I4T A;  1ZWW A;  1X03 A;  2EFL A;  2ELB A;  2RAJ A;  3HAH A;  4WPC A;  2YKT A;  2D1L A;  3OK8 A;  4H8S A;  4DYL A;  2D4C A;  1X04 A;  2Q12 A;  2X3X A;  2Q13 A;  2Z0V A;  3QE6 A;  3Q84 A;  3QNI A;  3I2W A;  3QWE A;  3HAI A;  2X3V A;  3SOG A;  3M3W A;  2RAI A;  4NSW A;  5C5B B;  1Y2O A;  2RAK A;  4DCN C;  3SYV A;  2X3W A;  3G9G A;  1I4L A;  4AKV A;  3LLL A;  1URU A;  3DYT A;  1I49 A;  2V0O A;  2Z0N A;  1I4D A;  3PLT A;  4FZS A;  4AVM A;  3HAJ A;  2EFK A;  4BNE A;  4ATM A;  3Q0K A;  5C5B A; 
#chains in the Genus database with same CATH topology
 2WYI A;  1OA0 A;  3ABH A;  3ACO A;  1ZWW A;  4EZV A;  2EFL A;  2OBL A;  4JWI A;  3I01 A;  5E84 A;  1SU7 A;  2Z8Y A;  3SOG A;  3BLB A;  2YIB A;  1SUF A;  2EFK A;  5FIG A;  2RT6 A;  4WPE A;  4AZ7 A;  3ER8 C;  1QWU A;  4I1Q A;  1TQU A;  3T46 A;  4EZQ A;  3D4Z A;  3LVT A;  3BUD A;  2F1A A;  4AZC B;  1SU8 A;  2GF4 A;  3QWE A;  2F18 A;  3M3W A;  3BUQ A;  1GNL A;  3DPP A;  4UDY X;  2OZN B;  3I04 A;  1U00 A;  1I49 A;  2WIN M;  4M0M A;  4IWO A;  3DX0 A;  3DPO A;  3RV1 A;  2YL9 A;  1I4T A;  1X03 A;  2ELB A;  3CZN A;  3D2F A;  3L3P A;  1DKY A;  4AZI A;  1QWN A;  1TQT A;  4HY9 A;  2QFF A;  4AZC A;  2OO2 A;  3OHX M;  4EZX A;  2NCZ A;  3LMF A;  1DKZ A;  4JN4 A;  3KAW A;  3RPM A;  2QXL A;  4EZZ A;  4R5L A;  4H8S A;  4JNF A;  3Q84 A;  3CVR A;  5FLE X;  1R5E A;  1GNT A;  2RAI A;  4PO2 A;  2MI7 A;  3BVT A;  3DPQ A;  3DYT A;  3EJT A;  4EZY A;  3Q0K A;  4AZ5 A;  3D50 A;  2YIV X;  5KBP A;  1LQ7 A;  1E9V A;  4EZS A;  1R34 A;  2D1L A;  3QA8 A;  4IW0 A;  2YIA A;  3BVU A;  2V0O A;  3ZED A;  4FZP A;  3DX2 A;  4JWD A;  3F7W A;  2RAJ A;  3QNJ A;  2O0I 1;  1OA1 A;  3C7N A;  2X3W A;  4AVM A;  4FM3 A;  2YI9 A;  3O3M B;  3DX1 A;  1HTY A;  3FD9 A;  4HYB A;  3O3O B;  2EX3 B;  2PY6 A;  2YL6 A;  3ER9 B;  1PS3 A;  4EZT A;  3SYV A;  4JWE A;  4IWP A;  3VEB A;  3LLL A;  3HAJ A;  2Z0O A;  3BVX A;  3O3N B;  2F1B A;  2OW7 A;  1R33 A;  4DYL A;  3ERC C;  4NPH A;  3B53 X;  3HAI A;  4EZU A;  4EZR A;  3VEA A;  2RAK A;  3OWG A;  4AZG A;  3CV5 A;  2YLA A;  4FZO A;  4EZN A;  1JQK A;  3D51 A;  2KHO A;  4R5G A;  3UIT A;  1OAO A;  2D4C A;  2Q13 A;  3D2E A;  1TQW A;  3DX4 A;  2YL8 A;  1YWM A;  3BUB A;  3BVV A;  4F00 A;  2N3K A;  3D52 A;  2EWF A;  3G9G A;  1SU6 A;  1URU A;  4AZB A;  2YI8 A;  2GAF D;  3PLT A;  3T49 A;  3B51 X;  3CAZ A;  4JWC A;  4NQI A;  4UDX X;  3T48 A;  4EZO A;  3GI7 A;  2Z0V A;  3QE6 A;  3B52 X;  2F7O A;  1W9M A;  4EZP A;  2F7Q A;  2JNS A;  3EJQ A;  1UPX A;  1E2U A;  4G6Q A;  4ATM A;  1QX1 A;  1O7D B;  3BVW A;  2X3X A;  4F01 A;  3QNI A;  2QKW A;  3CZS A;  3I39 X;  5C5B B;  4R5K A;  4JLC A;  4IWQ A;  2ZXQ A;  4AZH A;  2F7P A;  4E81 A;  1TQS A;  2X5C A;  4HR1 B;  2LXY A;  1TQV A;  4JNE A;  1DKX A;  3I2W A;  3KAV A;  3EJU A;  2X3V A;  1I4L A;  1E1D A;  2WYH A;  4E3C A;  4BNE A;  1I4D A;  3DX3 A;  5C5B A;  1O7D C;  2C08 A;  2YKT A;  2GA9 D;  2LM0 A;  4B9Q A;  2F7R A;  4HR1 A;  4AZ6 A;  1Y2O A;  1GN9 A;  4IM3 A;  2FYV A;  4R5J A;  2Z0N A;  3A98 A;  4KIK B;  3BUP A;  4EZW A;  1HWW A;  1ZYL A;  3RV0 A;  1X04 A;  2Q12 A;  3DDF A;  3KDR A;  2YLL A;  2YL5 A;  2OBM A;  3EJP A;  4H6I A;  4H6H A;  4IM2 A;  4FZS A;  3T47 A;  3EJS A;  2FIC A;  2JNK A;  3HAH A;  2ND1 A;  1HXK A;  4IM0 A;  4KIK A;  2PMR A;  2OW6 A;  4DCN C;  3EJR A;  1MJG A;  3BUI A;  1WDZ A;  3L3O M;  3VKH A;  3D4Y A;  5TKY A;  4WPC A;  3T4A G;  3DDG A;  3OK8 A;  2ALW A;  4R5I A;  4NSW A;  2ND0 A;  4AKV A;  4D8J A;  4JL9 A;  3CKD A; 
#chains in the Genus database with same CATH homology
 2Z0O A;  4WPE A;  2C08 A;  1WDZ A;  2FIC A;  3CAZ A;  4NQI A;  3ABH A;  4I1Q A;  3ACO A;  1I4T A;  1ZWW A;  1X03 A;  2EFL A;  2ELB A;  2RAJ A;  3HAH A;  4WPC A;  2YKT A;  2D1L A;  3OK8 A;  4H8S A;  4DYL A;  2D4C A;  1X04 A;  2Q12 A;  2X3X A;  2Q13 A;  2Z0V A;  3QE6 A;  3Q84 A;  3QNI A;  3I2W A;  3QWE A;  3HAI A;  2X3V A;  3SOG A;  3M3W A;  2RAI A;  4NSW A;  5C5B B;  1Y2O A;  2RAK A;  4DCN C;  3SYV A;  2X3W A;  3G9G A;  1I4L A;  4AKV A;  3LLL A;  1URU A;  3DYT A;  1I49 A;  2V0O A;  2Z0N A;  1I4D A;  3PLT A;  4FZS A;  4AVM A;  3HAJ A;  2EFK A;  4BNE A;  4ATM A;  3Q0K A;  5C5B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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