3SYVA

Crystal structure of mpacsin 3 f-bar domain mutant
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
285
structure length
249
Chain Sequence
SFWEAGNYRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLADWARKWRGAVEKGPQYGTLEKAWHAFFTAAERLSELHLEVREKLHGPDSERVRTWQRGAFHRQVLGGFRESRAAEDGFRKAQKPWLKRLKEVEASKKSYHTARKDEKEAEKMKTQYEQTLAELNRYTPRYMEDMEQAFESCQAAERQRLLFFKDVLLTLHQHLDLSSSDKFHELHRDLQQSIEAASDEEDLRWWRSTHGPGMAQF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Rigidity of wedge loop in PACSIN 3 protein is a key factor in dictating diameters of tubules
pubmed doi rcsb
molecule tags Endocytosis
source organism Mus musculus
molecule keywords Protein kinase C and casein kinase II substrate protein 3
total genus 106
structure length 249
sequence length 285
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature
pdb deposition date 2011-07-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3syvA01
3Q0KA 5C5BB 1URUA 3DYTA 3QNIA 4BNEA 4DYLA 2Q12A 1X03A 3HAHA 2YKTA 3ACOA 4AKVA 2Z0OA 2C08A 3QWEA 1I4TA 2X3XA 3M3WA 1ZWWA 2D4CA 3I2WA 1WDZA 1I4LA 4WPCA 4WPEA 3HAJA 4FZSA 2ELBA 3PLTA 2RAKA 2Z0NA 3ABHA 3Q84A 3CAZA 3QE6A 2EFKA 3G9GA 2RAIA 4I1QA 2Z0VA 2X3WA 3OK8A 2FICA 1I49A 2D1LA 3LLLA 4NQIA 2EFLA 3HAIA 2X3VA 4ATMA 4AVMA 2RAJA 2V0OA 3SOGA 2Q13A 4DCNC 1Y2OA 3SYVA 4H8SA 1I4DA 5C5BA 4NSWA 1X04A
chains in the Genus database with same CATH superfamily
1DKXA 4F00A 3T47A 3BUBA 2Q12A 3O3OB 2EX3B 4EZSA 1QX1A 4F01A 3HAJA 3Q84A 2WYIA 2X3VA 2QFFA 4NSWA 4JWDA 2OZNB 4JWEA 3OHXM 3VEAA 1ZWWA 4FM3A 3PLTA 2Z0VA 1HWWA 2OW7A 2YIVX 3L3OM 5KBPA 2N3KA 1OAOA 4R5LA 4AKVA 5C5BB 3CV5A 2QXLA 3RPMA 2OBMA 4JNFA 2YKTA 2F7PA 3QNJA 4EZWA 3BUQA 2ND1A 1TQTA 4UDXX 1I4LA 3C7NA 4AZCB 3B52X 3VEBA 3QA8A 4I1QA 4EZRA 4IWOA 2X3WA 3LLLA 1TQVA 4ATMA 4IM2A 2LM0A 1I4DA 2JNSA 1JQKA 3BVWA 2X5CA 3BUIA 4D8JA 2YL6A 3DX1A 1YWMA 4HR1A 5TKYA 1ZYLA 2FYVA 2RAIA 3I39X 4G6QA 1DKYA 2Q13A 4EZNA 2X3XA 2LXYA 3D52A 3DYTA 4HY9A 1E2UA 2D4CA 2F7OA 2OO2A 4HYBA 1MJGA 2YLAA 3DDGA 3CZNA 3D4YA 3OK8A 3DX2A 4NPHA 4R5IA 3KAVA 2F1BA 4IM0A 1R34A 2ND0A 1HXKA 4EZXA 1LQ7A 2ELBA 3BLBA 2RT6A 3CKDA 3ZEDA 3BUDA 3HAHA 1QWUA 1URUA 2O0I1 2YI9A 4JLCA 4PO2A 2YL5A 3DX3A 3I04A 4JWCA 3ABHA 1SU7A 3D2FA 4JWIA 4EZVA 2NCZA 2GAFD 4JN4A 3BVXA 1DKZA 3RV1A 4M0MA 1HTYA 3T4AG 3L3PA 1E1DA 3T46A 1OA1A 4R5JA 2OBLA 3DDFA 3SOGA 2WYHA 1W9MA 1X04A 4EZOA 3EJQA 4KIKB 1TQUA 4B9QA 3QWEA 4AZIA 4WPCA 2GA9D 2YIBA 3G9GA 3O3NB 1I49A 3A98A 3DX0A 3LVTA 2F7RA 5C5BA 2YL9A 4E3CA 4E81A 1E9VA 3BVVA 4FZOA 3EJTA 4AZHA 3BUPA 3D50A 1R33A 4AZBA 4IW0A 4AZCA 3I2WA 3T48A 3ER8C 2PY6A 4FZSA 2YL8A 1GN9A 2OW6A 3CAZA 3QE6A 2EFKA 3D51A 2V0OA 4H6IA 4H8SA 2F7QA 2PMRA 4EZYA 1R5EA 3DPOA 3EJRA 3DPPA 2KHOA 4EZZA 3EJSA 2RAKA 3EJUA 2ZXQA 4EZQA 3CZSA 2EFLA 3BVUA 4AVMA 1TQSA 2WINM 3KAWA 1SUFA 4FZPA 3T49A 2GF4A 4AZ7A 4IWPA 4JNEA 1TQWA 3ACOA 1UPXA 1I4TA 1QWNA 1SU6A 2F1AA 3M3WA 4AZ6A 3B51X 4H6HA 2D1LA 3OWGA 3HAIA 2RAJA 4EZTA 4DCNC 4AZGA 4BNEA 5FIGA 2Z8YA 4R5GA 3O3MB 5E84A 3DPQA 3KDRA 4HR1B 3D4ZA 1O7DC 3FD9A 2YI8A 1U00A 3QNIA 4AZ5A 3EJPA 2Z0OA 1O7DB 2EWFA 3F7WA 3GI7A 2FICA 3DX4A 4JL9A 1GNLA 4NQIA 3B53X 2YIAA 3D2EA 1Y2OA 4IWQA 2JNKA 4EZPA 4UDYX 4EZUA 1SU8A 5FLEX 3ERCC 1GNTA 2Z0NA 3VKHA 2F18A 2ALWA 3BVTA 3RV0A 3I01A 4R5KA 1PS3A 3SYVA 2QKWA 3ER9B 4KIKA 2YLLA 3UITA 3CVRA 3Q0KA 2MI7A 4DYLA 1X03A 3LMFA 2C08A 1WDZA 1OA0A 4WPEA 4IM3A
chains in the Genus database with same CATH topology
3Q0KA 5C5BB 1URUA 3DYTA 3QNIA 4BNEA 4DYLA 2Q12A 1X03A 3HAHA 2YKTA 3ACOA 4AKVA 2Z0OA 2C08A 3QWEA 1I4TA 2X3XA 3M3WA 1ZWWA 2D4CA 3I2WA 1WDZA 1I4LA 4WPCA 4WPEA 3HAJA 4FZSA 2ELBA 3PLTA 2RAKA 2Z0NA 3ABHA 3Q84A 3CAZA 3QE6A 2EFKA 3G9GA 2RAIA 4I1QA 2Z0VA 2X3WA 3OK8A 2FICA 1I49A 2D1LA 3LLLA 4NQIA 2EFLA 3HAIA 2X3VA 4ATMA 4AVMA 2RAJA 2V0OA 3SOGA 2Q13A 4DCNC 1Y2OA 3SYVA 4H8SA 1I4DA 5C5BA 4NSWA 1X04A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3Q0K A;  5C5B B;  1URU A;  3DYT A;  3QNI A;  4BNE A;  4DYL A;  2Q12 A;  1X03 A;  3HAH A;  2YKT A;  3ACO A;  4AKV A;  2Z0O A;  2C08 A;  3QWE A;  1I4T A;  2X3X A;  3M3W A;  1ZWW A;  2D4C A;  3I2W A;  1WDZ A;  1I4L A;  4WPC A;  4WPE A;  3HAJ A;  4FZS A;  2ELB A;  3PLT A;  2RAK A;  2Z0N A;  3ABH A;  3Q84 A;  3CAZ A;  3QE6 A;  2EFK A;  3G9G A;  2RAI A;  4I1Q A;  2Z0V A;  2X3W A;  3OK8 A;  2FIC A;  1I49 A;  2D1L A;  3LLL A;  4NQI A;  2EFL A;  3HAI A;  2X3V A;  4ATM A;  4AVM A;  2RAJ A;  2V0O A;  3SOG A;  2Q13 A;  4DCN C;  1Y2O A;  3SYV A;  4H8S A;  1I4D A;  5C5B A;  4NSW A;  1X04 A; 
#chains in the Genus database with same CATH topology
 1DKX A;  4F00 A;  3T47 A;  3BUB A;  2Q12 A;  3O3O B;  2EX3 B;  4EZS A;  1QX1 A;  4F01 A;  3HAJ A;  3Q84 A;  2WYI A;  2X3V A;  2QFF A;  4NSW A;  4JWD A;  2OZN B;  4JWE A;  3OHX M;  3VEA A;  1ZWW A;  4FM3 A;  3PLT A;  2Z0V A;  1HWW A;  2OW7 A;  2YIV X;  3L3O M;  5KBP A;  2N3K A;  1OAO A;  4R5L A;  4AKV A;  5C5B B;  3CV5 A;  2QXL A;  3RPM A;  2OBM A;  4JNF A;  2YKT A;  2F7P A;  3QNJ A;  4EZW A;  3BUQ A;  2ND1 A;  1TQT A;  4UDX X;  1I4L A;  3C7N A;  4AZC B;  3B52 X;  3VEB A;  3QA8 A;  4I1Q A;  4EZR A;  4IWO A;  2X3W A;  3LLL A;  1TQV A;  4ATM A;  4IM2 A;  2LM0 A;  1I4D A;  2JNS A;  1JQK A;  3BVW A;  2X5C A;  3BUI A;  4D8J A;  2YL6 A;  3DX1 A;  1YWM A;  4HR1 A;  5TKY A;  1ZYL A;  2FYV A;  2RAI A;  3I39 X;  4G6Q A;  1DKY A;  2Q13 A;  4EZN A;  2X3X A;  2LXY A;  3D52 A;  3DYT A;  4HY9 A;  1E2U A;  2D4C A;  2F7O A;  2OO2 A;  4HYB A;  1MJG A;  2YLA A;  3DDG A;  3CZN A;  3D4Y A;  3OK8 A;  3DX2 A;  4NPH A;  4R5I A;  3KAV A;  2F1B A;  4IM0 A;  1R34 A;  2ND0 A;  1HXK A;  4EZX A;  1LQ7 A;  2ELB A;  3BLB A;  2RT6 A;  3CKD A;  3ZED A;  3BUD A;  3HAH A;  1QWU A;  1URU A;  2O0I 1;  2YI9 A;  4JLC A;  4PO2 A;  2YL5 A;  3DX3 A;  3I04 A;  4JWC A;  3ABH A;  1SU7 A;  3D2F A;  4JWI A;  4EZV A;  2NCZ A;  2GAF D;  4JN4 A;  3BVX A;  1DKZ A;  3RV1 A;  4M0M A;  1HTY A;  3T4A G;  3L3P A;  1E1D A;  3T46 A;  1OA1 A;  4R5J A;  2OBL A;  3DDF A;  3SOG A;  2WYH A;  1W9M A;  1X04 A;  4EZO A;  3EJQ A;  4KIK B;  1TQU A;  4B9Q A;  3QWE A;  4AZI A;  4WPC A;  2GA9 D;  2YIB A;  3G9G A;  3O3N B;  1I49 A;  3A98 A;  3DX0 A;  3LVT A;  2F7R A;  5C5B A;  2YL9 A;  4E3C A;  4E81 A;  1E9V A;  3BVV A;  4FZO A;  3EJT A;  4AZH A;  3BUP A;  3D50 A;  1R33 A;  4AZB A;  4IW0 A;  4AZC A;  3I2W A;  3T48 A;  3ER8 C;  2PY6 A;  4FZS A;  2YL8 A;  1GN9 A;  2OW6 A;  3CAZ A;  3QE6 A;  2EFK A;  3D51 A;  2V0O A;  4H6I A;  4H8S A;  2F7Q A;  2PMR A;  4EZY A;  1R5E A;  3DPO A;  3EJR A;  3DPP A;  2KHO A;  4EZZ A;  3EJS A;  2RAK A;  3EJU A;  2ZXQ A;  4EZQ A;  3CZS A;  2EFL A;  3BVU A;  4AVM A;  1TQS A;  2WIN M;  3KAW A;  1SUF A;  4FZP A;  3T49 A;  2GF4 A;  4AZ7 A;  4IWP A;  4JNE A;  1TQW A;  3ACO A;  1UPX A;  1I4T A;  1QWN A;  1SU6 A;  2F1A A;  3M3W A;  4AZ6 A;  3B51 X;  4H6H A;  2D1L A;  3OWG A;  3HAI A;  2RAJ A;  4EZT A;  4DCN C;  4AZG A;  4BNE A;  5FIG A;  2Z8Y A;  4R5G A;  3O3M B;  5E84 A;  3DPQ A;  3KDR A;  4HR1 B;  3D4Z A;  1O7D C;  3FD9 A;  2YI8 A;  1U00 A;  3QNI A;  4AZ5 A;  3EJP A;  2Z0O A;  1O7D B;  2EWF A;  3F7W A;  3GI7 A;  2FIC A;  3DX4 A;  4JL9 A;  1GNL A;  4NQI A;  3B53 X;  2YIA A;  3D2E A;  1Y2O A;  4IWQ A;  2JNK A;  4EZP A;  4UDY X;  4EZU A;  1SU8 A;  5FLE X;  3ERC C;  1GNT A;  2Z0N A;  3VKH A;  2F18 A;  2ALW A;  3BVT A;  3RV0 A;  3I01 A;  4R5K A;  1PS3 A;  3SYV A;  2QKW A;  3ER9 B;  4KIK A;  2YLL A;  3UIT A;  3CVR A;  3Q0K A;  2MI7 A;  4DYL A;  1X03 A;  3LMF A;  2C08 A;  1WDZ A;  1OA0 A;  4WPE A;  4IM3 A; 
#chains in the Genus database with same CATH homology
 3Q0K A;  5C5B B;  1URU A;  3DYT A;  3QNI A;  4BNE A;  4DYL A;  2Q12 A;  1X03 A;  3HAH A;  2YKT A;  3ACO A;  4AKV A;  2Z0O A;  2C08 A;  3QWE A;  1I4T A;  2X3X A;  3M3W A;  1ZWW A;  2D4C A;  3I2W A;  1WDZ A;  1I4L A;  4WPC A;  4WPE A;  3HAJ A;  4FZS A;  2ELB A;  3PLT A;  2RAK A;  2Z0N A;  3ABH A;  3Q84 A;  3CAZ A;  3QE6 A;  2EFK A;  3G9G A;  2RAI A;  4I1Q A;  2Z0V A;  2X3W A;  3OK8 A;  2FIC A;  1I49 A;  2D1L A;  3LLL A;  4NQI A;  2EFL A;  3HAI A;  2X3V A;  4ATM A;  4AVM A;  2RAJ A;  2V0O A;  3SOG A;  2Q13 A;  4DCN C;  1Y2O A;  3SYV A;  4H8S A;  1I4D A;  5C5B A;  4NSW A;  1X04 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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