3VYGB

Crystal structure of thiocyanate hydrolase mutant r136w
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
152
structure length
152
Chain Sequence
SSIREEVHRHLGTVALMQPALHQQTHAPAPTEITHTLFRAYTRVPHDVGGEADVPIEYHEKEEEIWELNTFATCECLAWRGVWTAEERRRKQNCDVGQTVYLGMPYYGRWLLTAARILVDKQFVTLTELHNKIVEMRERVASGQGLGEYLPP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Effects of argnine residue around the substrate pocket on the substrate specificity of thiocyanate hydrolase
rcsb
molecule tags Hydrolase
source organism Thiobacillus thioparus
molecule keywords Thiocyanate hydrolase subunit alpha
total genus 42
structure length 152
sequence length 152
chains with identical sequence E, H, K
ec nomenclature ec 3.5.5.8: Thiocyanate hydrolase.
pdb deposition date 2012-09-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02211 NHase_beta Nitrile hydratase beta subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.472.20 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin A; domain 1 3vygB00
1IREB 4OB3B 2ZPGB 4ZGEB 1UGSB 2CZ0B 3X28B 3X20B 2DXCB 3HHTB 1UGQB 2ZPBB 2ZPHB 3A8HB 2AHJB 2D0QB 2ZPIB 3A8OB 3A8MB 3QZ5B 2DXBB 2ZPFB 3QXEB 1UGRB 3X24B 2DD5B 2ZCFB 3QYGB 3VYHB 4ZGDB 2DD4B 4FM4B 3WVEB 2CZ1B 1V29B 4OB2B 4OB0B 1AHJB 2DPPB 2CZ7B 2ZPEB 3VYGB 2CZ6B 3QZ9B 3QYHB 3X25B 1UGPB 3X26B 3WVDB 2ZZDB 3A8LB 4ZGJB 4OB1B 3A8GB 2QDYB 2CYZB
chains in the Genus database with same CATH superfamily
4OB3B 2BS4A 4BCNB 5IF1B 1VOLA 1XO2A 4EOPB 5BNJB 3BLRB 2WXVB 2QDJA 2UZLB 3DTOA 1QMZB 3TW7A 4F6UB 3F5XB 2JGZB 3HB9A 3A8OB 1OIUB 5L2WB 1GUXA 2DD4B 1PKDB 2PMIB 4HNUA 1E7PA 2WJ9A 2CYZB 2BS3A 4ELLA 4BCHB 4BCIB 1VYWB 4BBSM 2G9XB 3NDQA 4MIMA 2G77A 4OR5B 4MFEA 1TFBA 4RODA 3BHUB 3A8MB 4JX5A 2WFYB 4EC8B 2KR6A 3X24B 3QYGB 2WMAB 3KHIA 2KMGA 3G33B 4CFXB 3BHTB 4BY1X 4EOJB 2BKZB 4EOIB 4HLQA 4II5B 4F7LB 4HNVA 4CXAB 2WEVB 2D0QB 2PK2A 2WIPB 3MIAB 3VKGA 4BCMD 1KXUA 4ROCA 1H1PB 1AISB 2W9FA 4BCGB 4F6WB 2ZPGB 3PO3S 3POMA 2CZ0B 4AKHA 3HHTB 4F7JB 4YOOA 2W99A 3EIDB 2ZPFB 1JKWA 1UNHD 2W2HA 1URCB 3WVEB 4BCQD 2CZ1B 4BY7X 2ZZDB 3MY5B 1QLBA 2WPAB 1G3NC 3QYEA 2C4GB 2F2CA 3BG3A 3X28B 5IDNB 2ZPBB 2BS2A 2ZPIB 1W98B 2ZCFB 3VYHB 4AI6A 2CCIB 1JSTB 1OGUB 5DQVA 3DJBA 3A8LB 4JX6A 1AD6A 1VINA 3QHRB 4BCQB 4CFWB 1H28B 2B9RA 5DQWA 2UUEB 4AKIA 1V29B 2W9ZA 4EOSB 2QF7A 1UGPB 3BHVB 1P5EB 1F5QB 1D3UB 4UN0A 4BBRM 4EOLB 1UGQB 1FINB 3DOGB 3EOCB 2PHGA 3DDPB 3M03A 3BG5A 2PJQA 2EUFA 5ICPB 5I5ZB 4OB1B 1JSUB 4NSTB 4BCOB 2CCHB 4AKGA 4FX3B 4YOSA 5HBJB 2WHBB 1ZP2A 4I3ZB 3TNHB 4EOKB 1FKMA 4Z6YA 3BG9A 3HZJA 5HVYB 1OL1B 1H4LD 4BCPB 4OB0B 2IW9B 2IVXA 3QWLA 4TTHA 5LMKB 3A8GB 3LQ5B 4CFNB 1OIYB 2C6TB 4NC6A 3K7AM 3A8HB 1O9KB 4CFUD 3QZ5B 3GTMS 4EC9B 4ZGDB 3DDQB 5CYIB 4BCND 5EJCA 1H1QB 2CZ7B 4KRDB 1GY3B 4BCFB 4EORB 4ZGJB 2BPMB 4F7SB 5FGKB 1H25B 5IDPB 3O0GD 1H26B 5IHYA 4BCMB 1JOWA 2UZDB 1N4MA 1UGSB 4EONB 2WIHB 5CEIB 3HBLA 4EOQB 4FM4B 2QFZA 4G6LB 1GH6B 1AHJB 2UZEB 1OI9B 2ZPEB 3QZ9B 1BU2A 2IW6B 2X1NB 1C9BA 4ZGEB 1H24B 5EFQB 2C5OB 2DXCB 2I53A 4YOZA 2C5VB 4KRCB 4CFMB 2CZ6B 3X26B 2IN3A 2V22B 2QQ8A 4M6VA 2PK9B 3QXEB 1UGRB 1OKVB 2DD5B 4EOMB 4F6SB 2UZBB 5ACBA 1O9KA 4EOOB 3X20B 5HBHB 4YC3B 4CRLB 2AHJB 4ROEA 2DXBB 3H4CA 4F70B 1ENWA 4JX4A 4BXXX 3BLHB 4OB2B 2WMBB 3VKHA 2CJMB 3QYHB 3TN8B 4BCJB 5HBEB 1OKWB 1GUXB 2QDYB 1H27B 1H1RB 3MI9B 1FVVB 3TNIB 2QGSA 5LQFB 3QHWB 4F7NB 4QSHA 4IMYB 2DMEA 4Y72B 2R7GA 4ELJA 1UNLD 4HL4A 4BCKB 2DPPB 4MFDA 3VYGB 2LW4A 3TNWB 3RGFB 1TD6A 2I40B 2W96A 1IREB 2IW8B 1E9HB 3HO8A 2ZPHB 1H1SB 5HQ0B 3EJ1B 5HNBB 3MY1B 2C5XB 1UNGD 4CFVB 1OL2B 3B57A 4OGRB 2C5NB 4LOCA 3DL1A 3X25B 4HNTA 3WVDB 3BLQB 3TW6A 4CFUB 3QYBA
chains in the Genus database with same CATH topology
4OB3B 4AKGA 2BS4A 2ZPGB 2QQ8A 2CZ0B 4AKHA 3HHTB 1FKMA 4M6VA 4Z6YA 3BG9A 2ZPFB 3HZJA 3QXEB 1UGRB 2DD5B 3WVEB 2QDJA 2CZ1B 4OB0B 2ZZDB 3QWLA 1QLBA 3A8GB 3TW7A 3QYEA 4NC6A 3BG3A 3HB9A 3X28B 3X20B 3A8HB 2ZPBB 2BS2A 2AHJB 2ZPIB 3A8OB 3QZ5B 2DXBB 3H4CA 2ZCFB 3VYHB 4ZGDB 2DD4B 4JX4A 4AI6A 4OB2B 5EJCA 2CZ7B 3VKHA 3QYHB 4HNUA 3A8LB 4ZGJB 1E7PA 2WJ9A 4JX6A 2QDYB 2CYZB 2BS3A 4BBSM 1UGSB 4MIMA 2G77A 4MFEA 4QSHA 3A8MB 4AKIA 4JX5A 2KR6A 4ELJA 3X24B 4HL4A 3QYGB 3HBLA 4FM4B 2QFZA 1V29B 3KHIA 2KMGA 1AHJB 2DPPB 4MFDA 2ZPEB 2QF7A 3VYGB 3QZ9B 1UGPB 1IREB 4HLQA 3HO8A 4BBRM 4HNVA 4ZGEB 2DXCB 1UGQB 2ZPHB 2D0QB 3VKGA 4LOCA 3DL1A 2CZ6B 3X25B 3X26B 3BG5A 4HNTA 3WVDB 3TW6A 4OB1B 3QYBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IRE B;  4OB3 B;  2ZPG B;  4ZGE B;  1UGS B;  2CZ0 B;  3X28 B;  3X20 B;  2DXC B;  3HHT B;  1UGQ B;  2ZPB B;  2ZPH B;  3A8H B;  2AHJ B;  2D0Q B;  2ZPI B;  3A8O B;  3A8M B;  3QZ5 B;  2DXB B;  2ZPF B;  3QXE B;  1UGR B;  3X24 B;  2DD5 B;  2ZCF B;  3QYG B;  3VYH B;  4ZGD B;  2DD4 B;  4FM4 B;  3WVE B;  2CZ1 B;  1V29 B;  4OB2 B;  4OB0 B;  1AHJ B;  2DPP B;  2CZ7 B;  2ZPE B;  3VYG B;  2CZ6 B;  3QZ9 B;  3QYH B;  3X25 B;  1UGP B;  3X26 B;  3WVD B;  2ZZD B;  3A8L B;  4ZGJ B;  4OB1 B;  3A8G B;  2QDY B;  2CYZ B; 
#chains in the Genus database with same CATH topology
 4OB3 B;  2BS4 A;  4BCN B;  5IF1 B;  1VOL A;  1XO2 A;  4EOP B;  5BNJ B;  3BLR B;  2WXV B;  2QDJ A;  2UZL B;  3DTO A;  1QMZ B;  3TW7 A;  4F6U B;  3F5X B;  2JGZ B;  3HB9 A;  3A8O B;  1OIU B;  5L2W B;  1GUX A;  2DD4 B;  1PKD B;  2PMI B;  4HNU A;  1E7P A;  2WJ9 A;  2CYZ B;  2BS3 A;  4ELL A;  4BCH B;  4BCI B;  1VYW B;  4BBS M;  2G9X B;  3NDQ A;  4MIM A;  2G77 A;  4OR5 B;  4MFE A;  1TFB A;  4ROD A;  3BHU B;  3A8M B;  4JX5 A;  2WFY B;  4EC8 B;  2KR6 A;  3X24 B;  3QYG B;  2WMA B;  3KHI A;  2KMG A;  3G33 B;  4CFX B;  3BHT B;  4BY1 X;  4EOJ B;  2BKZ B;  4EOI B;  4HLQ A;  4II5 B;  4F7L B;  4HNV A;  4CXA B;  2WEV B;  2D0Q B;  2PK2 A;  2WIP B;  3MIA B;  3VKG A;  4BCM D;  1KXU A;  4ROC A;  1H1P B;  1AIS B;  2W9F A;  4BCG B;  4F6W B;  2ZPG B;  3PO3 S;  3POM A;  2CZ0 B;  4AKH A;  3HHT B;  4F7J B;  4YOO A;  2W99 A;  3EID B;  2ZPF B;  1JKW A;  1UNH D;  2W2H A;  1URC B;  3WVE B;  4BCQ D;  2CZ1 B;  4BY7 X;  2ZZD B;  3MY5 B;  1QLB A;  2WPA B;  1G3N C;  3QYE A;  2C4G B;  2F2C A;  3BG3 A;  3X28 B;  5IDN B;  2ZPB B;  2BS2 A;  2ZPI B;  1W98 B;  2ZCF B;  3VYH B;  4AI6 A;  2CCI B;  1JST B;  1OGU B;  5DQV A;  3DJB A;  3A8L B;  4JX6 A;  1AD6 A;  1VIN A;  3QHR B;  4BCQ B;  4CFW B;  1H28 B;  2B9R A;  5DQW A;  2UUE B;  4AKI A;  1V29 B;  2W9Z A;  4EOS B;  2QF7 A;  1UGP B;  3BHV B;  1P5E B;  1F5Q B;  1D3U B;  4UN0 A;  4BBR M;  4EOL B;  1UGQ B;  1FIN B;  3DOG B;  3EOC B;  2PHG A;  3DDP B;  3M03 A;  3BG5 A;  2PJQ A;  2EUF A;  5ICP B;  5I5Z B;  4OB1 B;  1JSU B;  4NST B;  4BCO B;  2CCH B;  4AKG A;  4FX3 B;  4YOS A;  5HBJ B;  2WHB B;  1ZP2 A;  4I3Z B;  3TNH B;  4EOK B;  1FKM A;  4Z6Y A;  3BG9 A;  3HZJ A;  5HVY B;  1OL1 B;  1H4L D;  4BCP B;  4OB0 B;  2IW9 B;  2IVX A;  3QWL A;  4TTH A;  5LMK B;  3A8G B;  3LQ5 B;  4CFN B;  1OIY B;  2C6T B;  4NC6 A;  3K7A M;  3A8H B;  1O9K B;  4CFU D;  3QZ5 B;  3GTM S;  4EC9 B;  4ZGD B;  3DDQ B;  5CYI B;  4BCN D;  5EJC A;  1H1Q B;  2CZ7 B;  4KRD B;  1GY3 B;  4BCF B;  4EOR B;  4ZGJ B;  2BPM B;  4F7S B;  5FGK B;  1H25 B;  5IDP B;  3O0G D;  1H26 B;  5IHY A;  4BCM B;  1JOW A;  2UZD B;  1N4M A;  1UGS B;  4EON B;  2WIH B;  5CEI B;  3HBL A;  4EOQ B;  4FM4 B;  2QFZ A;  4G6L B;  1GH6 B;  1AHJ B;  2UZE B;  1OI9 B;  2ZPE B;  3QZ9 B;  1BU2 A;  2IW6 B;  2X1N B;  1C9B A;  4ZGE B;  1H24 B;  5EFQ B;  2C5O B;  2DXC B;  2I53 A;  4YOZ A;  2C5V B;  4KRC B;  4CFM B;  2CZ6 B;  3X26 B;  2IN3 A;  2V22 B;  2QQ8 A;  4M6V A;  2PK9 B;  3QXE B;  1UGR B;  1OKV B;  2DD5 B;  4EOM B;  4F6S B;  2UZB B;  5ACB A;  1O9K A;  4EOO B;  3X20 B;  5HBH B;  4YC3 B;  4CRL B;  2AHJ B;  4ROE A;  2DXB B;  3H4C A;  4F70 B;  1ENW A;  4JX4 A;  4BXX X;  3BLH B;  4OB2 B;  2WMB B;  3VKH A;  2CJM B;  3QYH B;  3TN8 B;  4BCJ B;  5HBE B;  1OKW B;  1GUX B;  2QDY B;  1H27 B;  1H1R B;  3MI9 B;  1FVV B;  3TNI B;  2QGS A;  5LQF B;  3QHW B;  4F7N B;  4QSH A;  4IMY B;  2DME A;  4Y72 B;  2R7G A;  4ELJ A;  1UNL D;  4HL4 A;  4BCK B;  2DPP B;  4MFD A;  3VYG B;  2LW4 A;  3TNW B;  3RGF B;  1TD6 A;  2I40 B;  2W96 A;  1IRE B;  2IW8 B;  1E9H B;  3HO8 A;  2ZPH B;  1H1S B;  5HQ0 B;  3EJ1 B;  5HNB B;  3MY1 B;  2C5X B;  1UNG D;  4CFV B;  1OL2 B;  3B57 A;  4OGR B;  2C5N B;  4LOC A;  3DL1 A;  3X25 B;  4HNT A;  3WVD B;  3BLQ B;  3TW6 A;  4CFU B;  3QYB A; 
#chains in the Genus database with same CATH homology
 4OB3 B;  4AKG A;  2BS4 A;  2ZPG B;  2QQ8 A;  2CZ0 B;  4AKH A;  3HHT B;  1FKM A;  4M6V A;  4Z6Y A;  3BG9 A;  2ZPF B;  3HZJ A;  3QXE B;  1UGR B;  2DD5 B;  3WVE B;  2QDJ A;  2CZ1 B;  4OB0 B;  2ZZD B;  3QWL A;  1QLB A;  3A8G B;  3TW7 A;  3QYE A;  4NC6 A;  3BG3 A;  3HB9 A;  3X28 B;  3X20 B;  3A8H B;  2ZPB B;  2BS2 A;  2AHJ B;  2ZPI B;  3A8O B;  3QZ5 B;  2DXB B;  3H4C A;  2ZCF B;  3VYH B;  4ZGD B;  2DD4 B;  4JX4 A;  4AI6 A;  4OB2 B;  5EJC A;  2CZ7 B;  3VKH A;  3QYH B;  4HNU A;  3A8L B;  4ZGJ B;  1E7P A;  2WJ9 A;  4JX6 A;  2QDY B;  2CYZ B;  2BS3 A;  4BBS M;  1UGS B;  4MIM A;  2G77 A;  4MFE A;  4QSH A;  3A8M B;  4AKI A;  4JX5 A;  2KR6 A;  4ELJ A;  3X24 B;  4HL4 A;  3QYG B;  3HBL A;  4FM4 B;  2QFZ A;  1V29 B;  3KHI A;  2KMG A;  1AHJ B;  2DPP B;  4MFD A;  2ZPE B;  2QF7 A;  3VYG B;  3QZ9 B;  1UGP B;  1IRE B;  4HLQ A;  3HO8 A;  4BBR M;  4HNV A;  4ZGE B;  2DXC B;  1UGQ B;  2ZPH B;  2D0Q B;  3VKG A;  4LOC A;  3DL1 A;  2CZ6 B;  3X25 B;  3X26 B;  3BG5 A;  4HNT A;  3WVD B;  3TW6 A;  4OB1 B;  3QYB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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