4ATMA

Crystal structure of the bar domain of human amphiphysin, isoform 1 at 1.8 angstrom resolution featuring increased order at the n- terminus.
Total Genus 107
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
221
structure length
221
Chain Sequence
RAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDESLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Bar Domain of Human Amphiphysin, Isoform 1
rcsb
molecule tags Structural protein
source organism Homo sapiens
molecule keywords AMPHIPHYSIN
total genus 107
structure length 221
sequence length 221
ec nomenclature
pdb deposition date 2012-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03114 BAR BAR domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 4atmA00
3DYTA 4WPCA 5C5BB 2C08A 2D1LA 2V0OA 2Z0OA 3QWEA 3SYVA 1I4TA 1WDZA 4I1QA 4ATMA 5C5BA 2X3WA 2EFKA 3CAZA 4AKVA 2D4CA 1Y2OA 3M3WA 3SOGA 1URUA 1X04A 2RAIA 3QE6A 2X3XA 1I4DA 2RAJA 2Z0NA 4NSWA 3Q0KA 2FICA 3QNIA 2Q13A 4FZSA 1I4LA 3G9GA 4H8SA 4DYLA 2YKTA 4WPEA 1I49A 4BNEA 4AVMA 2EFLA 3HAHA 3HAJA 3Q84A 3ABHA 3ACOA 3OK8A 3HAIA 2X3VA 3LLLA 4NQIA 4DCNC 1ZWWA 2Q12A 2ELBA 2RAKA 1X03A 3I2WA 2Z0VA 3PLTA
chains in the Genus database with same CATH superfamily
4EZVA 2C08A 3CZNA 4AKVA 1SU6A 4E3CA 3RV1A 2FICA 2EX3B 1SU7A 4FZPA 3O3MB 2EFLA 3QA8A 4JWDA 3ACOA 1DKYA 3BUQA 2ALWA 3B51X 3SYVA 2EWFA 4IM3A 1URUA 1GNLA 1I4DA 3D2FA 2GF4A 4AZIA 1U00A 4R5LA 4JWEA 1OA0A 1E1DA 3BUBA 2ND1A 2Z8YA 3LLLA 4AZ6A 4E81A 2ND0A 1O7DC 2RAIA 2Z0NA 3DX1A 1I49A 1SUFA 2LXYA 3BUIA 3ERCC 3DX2A 4HR1A 4DCNC 3OWGA 1X03A 2Z0VA 2V0OA 3L3OM 2OZNB 2FYVA 4HR1B 2LM0A 3T49A 2ELBA 4JWCA 4ATMA 2QKWA 3PLTA 2OW7A 4D8JA 4B9QA 3Q0KA 1R34A 2Q13A 4FZSA 3A98A 3UITA 1E2UA 4H6HA 3BVXA 3HAIA 2WYHA 1ZYLA 5KBPA 2RAKA 3I04A 3KAWA 2EFKA 4IM0A 4EZZA 3EJRA 4HY9A 2YIBA 2RAJA 4JN4A 4R5IA 2F7QA 2X3VA 4F00A 3BVUA 3FD9A 4UDYX 1DKXA 3BVVA 4WPCA 3DDGA 1SU8A 4R5GA 1QX1A 2JNSA 3DPPA 1GNTA 4EZNA 2QXLA 2F7OA 4BNEA 3BLBA 3DPOA 2OW6A 3QWEA 2YL9A 3C7NA 3M3WA 4F01A 3VEBA 3T47A 4H8SA 2F1AA 4JWIA 1HTYA 2F1BA 4FZOA 2NCZA 3ER8C 4AZGA 5FIGA 3I2WA 3BUDA 2YLLA 1TQVA 2GA9D 1I4TA 1WDZA 1E9VA 5C5BA 2X3WA 3LVTA 2YL6A 4M0MA 3F7WA 5FLEX 1DKZA 3D4YA 4HYBA 3RPMA 5TKYA 4JNFA 2F7RA 3HAJA 4PO2A 3OHXM 3VKHA 3D2EA 5C5BB 2Z0OA 4H6IA 4AZ7A 3D50A 1X04A 2ZXQA 4IM2A 4NSWA 4UDXX 2KHOA 4DYLA 3QNJA 3ZEDA 2OBMA 4R5KA 3L3PA 1LQ7A 4EZWA 3CV5A 4EZTA 1TQUA 2YIAA 3ABHA 2YL5A 2Q12A 3LMFA 4AZCA 3EJUA 3DX4A 1PS3A 3O3NB 1HXKA 3EJSA 2QFFA 3KAVA 2GAFD 4AZHA 1JQKA 3EJTA 3OK8A 4AZCB 2YIVX 1OA1A 1QWUA 2WYIA 2X5CA 1QWNA 2YLAA 3CVRA 3DX3A 1R5EA 2YI8A 4AZ5A 3CKDA 1O7DB 4R5JA 4G6QA 3T48A 4EZYA 3DX0A 2D1LA 4IWPA 4AZBA 3DDFA 3CAZA 4EZXA 4JNEA 2D4CA 1UPXA 4EZRA 3VEAA 3DPQA 3QNIA 2YL8A 4WPEA 4NPHA 3HAHA 2OO2A 4IWOA 1R33A 4EZSA 2PY6A 3RV0A 4EZUA 4JL9A 1HWWA 1TQWA 3B52X 3T46A 3T4AG 3D52A 4EZQA 4I1QA 3KDRA 4JLCA 4EZOA 3QE6A 2N3KA 1I4LA 3G9GA 5E84A 2F7PA 4KIKA 4IWQA 4NQIA 3O3OB 1ZWWA 1TQTA 2RT6A 2OBLA 1MJGA 1Y2OA 3BUPA 1GN9A 3D51A 2X3XA 4IW0A 1TQSA 3I39X 3EJQA 2MI7A 2JNKA 4KIKB 1W9MA 3CZSA 1OAOA 2WINM 3BVWA 2YI9A 3ER9B 2O0I1 3I01A 3DYTA 1YWMA 2F18A 2PMRA 3SOGA 4FM3A 3GI7A 3D4ZA 3BVTA 2YKTA 4EZPA 3B53X 3EJPA 3Q84A 4AVMA
chains in the Genus database with same CATH topology
3DYTA 4WPCA 5C5BB 2C08A 2D1LA 2V0OA 2Z0OA 3QWEA 3SYVA 1I4TA 1WDZA 4I1QA 4ATMA 5C5BA 2X3WA 2EFKA 3CAZA 4AKVA 2D4CA 1Y2OA 3M3WA 3SOGA 1URUA 1X04A 2RAIA 3QE6A 2X3XA 1I4DA 2RAJA 2Z0NA 4NSWA 3Q0KA 2FICA 3QNIA 2Q13A 4FZSA 1I4LA 3G9GA 4H8SA 4DYLA 2YKTA 4WPEA 1I49A 4BNEA 4AVMA 2EFLA 3HAHA 3HAJA 3Q84A 3ABHA 3ACOA 3OK8A 3HAIA 2X3VA 3LLLA 4NQIA 4DCNC 1ZWWA 2Q12A 2ELBA 2RAKA 1X03A 3I2WA 2Z0VA 3PLTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DYT A;  4WPC A;  5C5B B;  2C08 A;  2D1L A;  2V0O A;  2Z0O A;  3QWE A;  3SYV A;  1I4T A;  1WDZ A;  4I1Q A;  4ATM A;  5C5B A;  2X3W A;  2EFK A;  3CAZ A;  4AKV A;  2D4C A;  1Y2O A;  3M3W A;  3SOG A;  1URU A;  1X04 A;  2RAI A;  3QE6 A;  2X3X A;  1I4D A;  2RAJ A;  2Z0N A;  4NSW A;  3Q0K A;  2FIC A;  3QNI A;  2Q13 A;  4FZS A;  1I4L A;  3G9G A;  4H8S A;  4DYL A;  2YKT A;  4WPE A;  1I49 A;  4BNE A;  4AVM A;  2EFL A;  3HAH A;  3HAJ A;  3Q84 A;  3ABH A;  3ACO A;  3OK8 A;  3HAI A;  2X3V A;  3LLL A;  4NQI A;  4DCN C;  1ZWW A;  2Q12 A;  2ELB A;  2RAK A;  1X03 A;  3I2W A;  2Z0V A;  3PLT A; 
#chains in the Genus database with same CATH topology
 4EZV A;  2C08 A;  3CZN A;  4AKV A;  1SU6 A;  4E3C A;  3RV1 A;  2FIC A;  2EX3 B;  1SU7 A;  4FZP A;  3O3M B;  2EFL A;  3QA8 A;  4JWD A;  3ACO A;  1DKY A;  3BUQ A;  2ALW A;  3B51 X;  3SYV A;  2EWF A;  4IM3 A;  1URU A;  1GNL A;  1I4D A;  3D2F A;  2GF4 A;  4AZI A;  1U00 A;  4R5L A;  4JWE A;  1OA0 A;  1E1D A;  3BUB A;  2ND1 A;  2Z8Y A;  3LLL A;  4AZ6 A;  4E81 A;  2ND0 A;  1O7D C;  2RAI A;  2Z0N A;  3DX1 A;  1I49 A;  1SUF A;  2LXY A;  3BUI A;  3ERC C;  3DX2 A;  4HR1 A;  4DCN C;  3OWG A;  1X03 A;  2Z0V A;  2V0O A;  3L3O M;  2OZN B;  2FYV A;  4HR1 B;  2LM0 A;  3T49 A;  2ELB A;  4JWC A;  4ATM A;  2QKW A;  3PLT A;  2OW7 A;  4D8J A;  4B9Q A;  3Q0K A;  1R34 A;  2Q13 A;  4FZS A;  3A98 A;  3UIT A;  1E2U A;  4H6H A;  3BVX A;  3HAI A;  2WYH A;  1ZYL A;  5KBP A;  2RAK A;  3I04 A;  3KAW A;  2EFK A;  4IM0 A;  4EZZ A;  3EJR A;  4HY9 A;  2YIB A;  2RAJ A;  4JN4 A;  4R5I A;  2F7Q A;  2X3V A;  4F00 A;  3BVU A;  3FD9 A;  4UDY X;  1DKX A;  3BVV A;  4WPC A;  3DDG A;  1SU8 A;  4R5G A;  1QX1 A;  2JNS A;  3DPP A;  1GNT A;  4EZN A;  2QXL A;  2F7O A;  4BNE A;  3BLB A;  3DPO A;  2OW6 A;  3QWE A;  2YL9 A;  3C7N A;  3M3W A;  4F01 A;  3VEB A;  3T47 A;  4H8S A;  2F1A A;  4JWI A;  1HTY A;  2F1B A;  4FZO A;  2NCZ A;  3ER8 C;  4AZG A;  5FIG A;  3I2W A;  3BUD A;  2YLL A;  1TQV A;  2GA9 D;  1I4T A;  1WDZ A;  1E9V A;  5C5B A;  2X3W A;  3LVT A;  2YL6 A;  4M0M A;  3F7W A;  5FLE X;  1DKZ A;  3D4Y A;  4HYB A;  3RPM A;  5TKY A;  4JNF A;  2F7R A;  3HAJ A;  4PO2 A;  3OHX M;  3VKH A;  3D2E A;  5C5B B;  2Z0O A;  4H6I A;  4AZ7 A;  3D50 A;  1X04 A;  2ZXQ A;  4IM2 A;  4NSW A;  4UDX X;  2KHO A;  4DYL A;  3QNJ A;  3ZED A;  2OBM A;  4R5K A;  3L3P A;  1LQ7 A;  4EZW A;  3CV5 A;  4EZT A;  1TQU A;  2YIA A;  3ABH A;  2YL5 A;  2Q12 A;  3LMF A;  4AZC A;  3EJU A;  3DX4 A;  1PS3 A;  3O3N B;  1HXK A;  3EJS A;  2QFF A;  3KAV A;  2GAF D;  4AZH A;  1JQK A;  3EJT A;  3OK8 A;  4AZC B;  2YIV X;  1OA1 A;  1QWU A;  2WYI A;  2X5C A;  1QWN A;  2YLA A;  3CVR A;  3DX3 A;  1R5E A;  2YI8 A;  4AZ5 A;  3CKD A;  1O7D B;  4R5J A;  4G6Q A;  3T48 A;  4EZY A;  3DX0 A;  2D1L A;  4IWP A;  4AZB A;  3DDF A;  3CAZ A;  4EZX A;  4JNE A;  2D4C A;  1UPX A;  4EZR A;  3VEA A;  3DPQ A;  3QNI A;  2YL8 A;  4WPE A;  4NPH A;  3HAH A;  2OO2 A;  4IWO A;  1R33 A;  4EZS A;  2PY6 A;  3RV0 A;  4EZU A;  4JL9 A;  1HWW A;  1TQW A;  3B52 X;  3T46 A;  3T4A G;  3D52 A;  4EZQ A;  4I1Q A;  3KDR A;  4JLC A;  4EZO A;  3QE6 A;  2N3K A;  1I4L A;  3G9G A;  5E84 A;  2F7P A;  4KIK A;  4IWQ A;  4NQI A;  3O3O B;  1ZWW A;  1TQT A;  2RT6 A;  2OBL A;  1MJG A;  1Y2O A;  3BUP A;  1GN9 A;  3D51 A;  2X3X A;  4IW0 A;  1TQS A;  3I39 X;  3EJQ A;  2MI7 A;  2JNK A;  4KIK B;  1W9M A;  3CZS A;  1OAO A;  2WIN M;  3BVW A;  2YI9 A;  3ER9 B;  2O0I 1;  3I01 A;  3DYT A;  1YWM A;  2F18 A;  2PMR A;  3SOG A;  4FM3 A;  3GI7 A;  3D4Z A;  3BVT A;  2YKT A;  4EZP A;  3B53 X;  3EJP A;  3Q84 A;  4AVM A; 
#chains in the Genus database with same CATH homology
 3DYT A;  4WPC A;  5C5B B;  2C08 A;  2D1L A;  2V0O A;  2Z0O A;  3QWE A;  3SYV A;  1I4T A;  1WDZ A;  4I1Q A;  4ATM A;  5C5B A;  2X3W A;  2EFK A;  3CAZ A;  4AKV A;  2D4C A;  1Y2O A;  3M3W A;  3SOG A;  1URU A;  1X04 A;  2RAI A;  3QE6 A;  2X3X A;  1I4D A;  2RAJ A;  2Z0N A;  4NSW A;  3Q0K A;  2FIC A;  3QNI A;  2Q13 A;  4FZS A;  1I4L A;  3G9G A;  4H8S A;  4DYL A;  2YKT A;  4WPE A;  1I49 A;  4BNE A;  4AVM A;  2EFL A;  3HAH A;  3HAJ A;  3Q84 A;  3ABH A;  3ACO A;  3OK8 A;  3HAI A;  2X3V A;  3LLL A;  4NQI A;  4DCN C;  1ZWW A;  2Q12 A;  2ELB A;  2RAK A;  1X03 A;  3I2W A;  2Z0V A;  3PLT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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