4AVMA

Crystal structure of the n-bar domain of human bridging integrator 2.
Total Genus 110
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
110
sequence length
230
structure length
230
Chain Sequence
KQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHKLYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLADQAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNKAQTVFEDLNQELLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLERQHSN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the N-Bar Domain of Human Bridging Integrator 2.
rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords BRIDGING INTEGRATOR 2
total genus 110
structure length 230
sequence length 230
ec nomenclature
pdb deposition date 2012-05-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03114 BAR BAR domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 4avmA00
1X03A 2YKTA 2X3WA 2D1LA 2Z0VA 2Z0OA 3CAZA 2EFLA 1I4LA 3QE6A 2Z0NA 3ACOA 3PLTA 3SYVA 4AKVA 1I4TA 4DCNC 3DYTA 4FZSA 4NSWA 3QWEA 2RAIA 3QNIA 2C08A 2Q12A 4H8SA 3HAHA 3Q0KA 4NQIA 2X3VA 4ATMA 3OK8A 3Q84A 2RAKA 2FICA 3I2WA 4WPEA 2RAJA 1X04A 2EFKA 1I49A 5C5BB 4DYLA 1Y2OA 2V0OA 3LLLA 2X3XA 2ELBA 3HAJA 5C5BA 4AVMA 2D4CA 1WDZA 1ZWWA 3M3WA 1URUA 3G9GA 3SOGA 2Q13A 4BNEA 4WPCA 3HAIA 3ABHA 4I1QA 1I4DA
chains in the Genus database with same CATH superfamily
3B53X 1OAOA 2QXLA 2YLAA 3BUQA 4NQIA 2PY6A 2X3VA 4AZ6A 3BLBA 3I2WA 2KHOA 1HTYA 2OZNB 1OA1A 2EFKA 2ND1A 2D4CA 1SU7A 4R5KA 3EJPA 1URUA 4F01A 3HAIA 4EZYA 2F7RA 4IM2A 4FZOA 3QE6A 2RT6A 4DCNC 2ZXQA 3BVWA 3RV0A 1R34A 3FD9A 2WYIA 3DX1A 2F7OA 5C5BB 2V0OA 3B51X 4BNEA 3EJQA 4HR1A 4AZIA 2YL5A 3QA8A 4AKVA 3F7WA 3ERCC 4NSWA 2NCZA 1TQUA 3QNIA 2ALWA 3A98A 4D8JA 1OA0A 2RAKA 3QNJA 2MI7A 3CV5A 3EJUA 3DX3A 3DX2A 2OBLA 2OBMA 3EJRA 1TQSA 1DKXA 3L3PA 4JWCA 4HY9A 4AZBA 3BUDA 3BVUA 4JL9A 4IWQA 4HYBA 4R5LA 4JWIA 3DX0A 2YL8A 4UDYX 1SUFA 2Z8YA 4KIKB 3T49A 3BUBA 1TQTA 4AZCB 4I1QA 3BVTA 3SYVA 3KDRA 4PO2A 4WPEA 4EZWA 1X04A 1HXKA 3O3MB 1DKYA 3T4AG 5C5BA 1TQWA 4WPCA 4EZXA 1O7DC 4EZUA 2F18A 3L3OM 4EZRA 2WYHA 3QWEA 3ZEDA 3OK8A 2FICA 3D2FA 3I04A 3M3WA 1YWMA 3BVXA 3EJSA 4FM3A 3ABHA 3OWGA 3D50A 3B52X 2F1AA 4JWEA 3EJTA 5KBPA 3LLLA 3VEBA 4AZGA 4KIKA 3C7NA 3CZNA 3PLTA 2OW7A 4JN4A 3Q0KA 4JNFA 2F1BA 2EX3B 3D4ZA 4IM0A 1E9VA 1SU6A 2X5CA 4M0MA 2X3WA 3RV1A 3O3NB 3ER8C 2Q12A 5E84A 1R33A 1I49A 4EZQA 2YLLA 4AZ5A 4JNEA 2YIBA 2OO2A 4H6IA 1MJGA 3KAVA 3DYTA 4FZSA 2PMRA 4B9QA 1R5EA 1HWWA 1TQVA 1ZYLA 1E2UA 1QX1A 2O0I1 3DPOA 4JWDA 2JNSA 2GAFD 1GNLA 3LVTA 2GF4A 4IWPA 2YIVX 2GA9D 1I4LA 3O3OB 2YL9A 4EZNA 3BUIA 3Q84A 2EWFA 3BUPA 4UDXX 4IW0A 1GNTA 1QWNA 2ELBA 3UITA 3I01A 3DPQA 4E81A 2Z0OA 2Z0NA 4E3CA 3D52A 3T46A 3KAWA 3VKHA 3BVVA 4G6QA 2ND0A 3HAJA 1WDZA 4R5GA 4IM3A 3DDFA 5FIGA 3LMFA 3CKDA 1UPXA 3T48A 4EZOA 2D1LA 4AZCA 2Z0VA 2YI8A 1I4TA 2YL6A 1O7DB 5TKYA 1JQKA 4EZZA 2WINM 1GN9A 4ATMA 3ER9B 2OW6A 2JNKA 4NPHA 3D2EA 3GI7A 2X3XA 3CVRA 1U00A 3VEAA 5FLEX 2QKWA 2LXYA 1PS3A 1I4DA 1W9MA 4F00A 2YIAA 3HAHA 2F7PA 1LQ7A 4R5IA 1DKZA 3G9GA 2Q13A 4H6HA 2LM0A 2EFLA 3DDGA 2QFFA 3T47A 2C08A 4FZPA 4EZSA 2RAJA 4DYLA 1E1DA 4AVMA 3D51A 4HR1B 4EZVA 3RPMA 1X03A 2YKTA 3DPPA 4AZ7A 3CAZA 3ACOA 2F7QA 2RAIA 4H8SA 4JLCA 1SU8A 4EZPA 3DX4A 2YI9A 3CZSA 3D4YA 4EZTA 1Y2OA 4AZHA 1ZWWA 4R5JA 4IWOA 2N3KA 3SOGA 3OHXM 2FYVA 3I39X 1QWUA
chains in the Genus database with same CATH topology
1X03A 2YKTA 2X3WA 2D1LA 2Z0VA 2Z0OA 3CAZA 2EFLA 1I4LA 3QE6A 2Z0NA 3ACOA 3PLTA 3SYVA 4AKVA 1I4TA 4DCNC 3DYTA 4FZSA 4NSWA 3QWEA 2RAIA 3QNIA 2C08A 2Q12A 4H8SA 3HAHA 3Q0KA 4NQIA 2X3VA 4ATMA 3OK8A 3Q84A 2RAKA 2FICA 3I2WA 4WPEA 2RAJA 1X04A 2EFKA 1I49A 5C5BB 4DYLA 1Y2OA 2V0OA 3LLLA 2X3XA 2ELBA 3HAJA 5C5BA 4AVMA 2D4CA 1WDZA 1ZWWA 3M3WA 1URUA 3G9GA 3SOGA 2Q13A 4BNEA 4WPCA 3HAIA 3ABHA 4I1QA 1I4DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1X03 A;  2YKT A;  2X3W A;  2D1L A;  2Z0V A;  2Z0O A;  3CAZ A;  2EFL A;  1I4L A;  3QE6 A;  2Z0N A;  3ACO A;  3PLT A;  3SYV A;  4AKV A;  1I4T A;  4DCN C;  3DYT A;  4FZS A;  4NSW A;  3QWE A;  2RAI A;  3QNI A;  2C08 A;  2Q12 A;  4H8S A;  3HAH A;  3Q0K A;  4NQI A;  2X3V A;  4ATM A;  3OK8 A;  3Q84 A;  2RAK A;  2FIC A;  3I2W A;  4WPE A;  2RAJ A;  1X04 A;  2EFK A;  1I49 A;  5C5B B;  4DYL A;  1Y2O A;  2V0O A;  3LLL A;  2X3X A;  2ELB A;  3HAJ A;  5C5B A;  4AVM A;  2D4C A;  1WDZ A;  1ZWW A;  3M3W A;  1URU A;  3G9G A;  3SOG A;  2Q13 A;  4BNE A;  4WPC A;  3HAI A;  3ABH A;  4I1Q A;  1I4D A; 
#chains in the Genus database with same CATH topology
 3B53 X;  1OAO A;  2QXL A;  2YLA A;  3BUQ A;  4NQI A;  2PY6 A;  2X3V A;  4AZ6 A;  3BLB A;  3I2W A;  2KHO A;  1HTY A;  2OZN B;  1OA1 A;  2EFK A;  2ND1 A;  2D4C A;  1SU7 A;  4R5K A;  3EJP A;  1URU A;  4F01 A;  3HAI A;  4EZY A;  2F7R A;  4IM2 A;  4FZO A;  3QE6 A;  2RT6 A;  4DCN C;  2ZXQ A;  3BVW A;  3RV0 A;  1R34 A;  3FD9 A;  2WYI A;  3DX1 A;  2F7O A;  5C5B B;  2V0O A;  3B51 X;  4BNE A;  3EJQ A;  4HR1 A;  4AZI A;  2YL5 A;  3QA8 A;  4AKV A;  3F7W A;  3ERC C;  4NSW A;  2NCZ A;  1TQU A;  3QNI A;  2ALW A;  3A98 A;  4D8J A;  1OA0 A;  2RAK A;  3QNJ A;  2MI7 A;  3CV5 A;  3EJU A;  3DX3 A;  3DX2 A;  2OBL A;  2OBM A;  3EJR A;  1TQS A;  1DKX A;  3L3P A;  4JWC A;  4HY9 A;  4AZB A;  3BUD A;  3BVU A;  4JL9 A;  4IWQ A;  4HYB A;  4R5L A;  4JWI A;  3DX0 A;  2YL8 A;  4UDY X;  1SUF A;  2Z8Y A;  4KIK B;  3T49 A;  3BUB A;  1TQT A;  4AZC B;  4I1Q A;  3BVT A;  3SYV A;  3KDR A;  4PO2 A;  4WPE A;  4EZW A;  1X04 A;  1HXK A;  3O3M B;  1DKY A;  3T4A G;  5C5B A;  1TQW A;  4WPC A;  4EZX A;  1O7D C;  4EZU A;  2F18 A;  3L3O M;  4EZR A;  2WYH A;  3QWE A;  3ZED A;  3OK8 A;  2FIC A;  3D2F A;  3I04 A;  3M3W A;  1YWM A;  3BVX A;  3EJS A;  4FM3 A;  3ABH A;  3OWG A;  3D50 A;  3B52 X;  2F1A A;  4JWE A;  3EJT A;  5KBP A;  3LLL A;  3VEB A;  4AZG A;  4KIK A;  3C7N A;  3CZN A;  3PLT A;  2OW7 A;  4JN4 A;  3Q0K A;  4JNF A;  2F1B A;  2EX3 B;  3D4Z A;  4IM0 A;  1E9V A;  1SU6 A;  2X5C A;  4M0M A;  2X3W A;  3RV1 A;  3O3N B;  3ER8 C;  2Q12 A;  5E84 A;  1R33 A;  1I49 A;  4EZQ A;  2YLL A;  4AZ5 A;  4JNE A;  2YIB A;  2OO2 A;  4H6I A;  1MJG A;  3KAV A;  3DYT A;  4FZS A;  2PMR A;  4B9Q A;  1R5E A;  1HWW A;  1TQV A;  1ZYL A;  1E2U A;  1QX1 A;  2O0I 1;  3DPO A;  4JWD A;  2JNS A;  2GAF D;  1GNL A;  3LVT A;  2GF4 A;  4IWP A;  2YIV X;  2GA9 D;  1I4L A;  3O3O B;  2YL9 A;  4EZN A;  3BUI A;  3Q84 A;  2EWF A;  3BUP A;  4UDX X;  4IW0 A;  1GNT A;  1QWN A;  2ELB A;  3UIT A;  3I01 A;  3DPQ A;  4E81 A;  2Z0O A;  2Z0N A;  4E3C A;  3D52 A;  3T46 A;  3KAW A;  3VKH A;  3BVV A;  4G6Q A;  2ND0 A;  3HAJ A;  1WDZ A;  4R5G A;  4IM3 A;  3DDF A;  5FIG A;  3LMF A;  3CKD A;  1UPX A;  3T48 A;  4EZO A;  2D1L A;  4AZC A;  2Z0V A;  2YI8 A;  1I4T A;  2YL6 A;  1O7D B;  5TKY A;  1JQK A;  4EZZ A;  2WIN M;  1GN9 A;  4ATM A;  3ER9 B;  2OW6 A;  2JNK A;  4NPH A;  3D2E A;  3GI7 A;  2X3X A;  3CVR A;  1U00 A;  3VEA A;  5FLE X;  2QKW A;  2LXY A;  1PS3 A;  1I4D A;  1W9M A;  4F00 A;  2YIA A;  3HAH A;  2F7P A;  1LQ7 A;  4R5I A;  1DKZ A;  3G9G A;  2Q13 A;  4H6H A;  2LM0 A;  2EFL A;  3DDG A;  2QFF A;  3T47 A;  2C08 A;  4FZP A;  4EZS A;  2RAJ A;  4DYL A;  1E1D A;  4AVM A;  3D51 A;  4HR1 B;  4EZV A;  3RPM A;  1X03 A;  2YKT A;  3DPP A;  4AZ7 A;  3CAZ A;  3ACO A;  2F7Q A;  2RAI A;  4H8S A;  4JLC A;  1SU8 A;  4EZP A;  3DX4 A;  2YI9 A;  3CZS A;  3D4Y A;  4EZT A;  1Y2O A;  4AZH A;  1ZWW A;  4R5J A;  4IWO A;  2N3K A;  3SOG A;  3OHX M;  2FYV A;  3I39 X;  1QWU A; 
#chains in the Genus database with same CATH homology
 1X03 A;  2YKT A;  2X3W A;  2D1L A;  2Z0V A;  2Z0O A;  3CAZ A;  2EFL A;  1I4L A;  3QE6 A;  2Z0N A;  3ACO A;  3PLT A;  3SYV A;  4AKV A;  1I4T A;  4DCN C;  3DYT A;  4FZS A;  4NSW A;  3QWE A;  2RAI A;  3QNI A;  2C08 A;  2Q12 A;  4H8S A;  3HAH A;  3Q0K A;  4NQI A;  2X3V A;  4ATM A;  3OK8 A;  3Q84 A;  2RAK A;  2FIC A;  3I2W A;  4WPE A;  2RAJ A;  1X04 A;  2EFK A;  1I49 A;  5C5B B;  4DYL A;  1Y2O A;  2V0O A;  3LLL A;  2X3X A;  2ELB A;  3HAJ A;  5C5B A;  4AVM A;  2D4C A;  1WDZ A;  1ZWW A;  3M3W A;  1URU A;  3G9G A;  3SOG A;  2Q13 A;  4BNE A;  4WPC A;  3HAI A;  3ABH A;  4I1Q A;  1I4D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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