4CFMB

Structure-based design of c8-substituted o6-cyclohexylmethoxyguanine cdk1 and 2 inhibitors.
Total Genus 93
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
93
sequence length
258
structure length
258
Chain Sequence
VPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
3H2 (199-202)EMPTY3H1 (176-178)AH2 (208-225)AH1 (179-193)TI1 (196-199)TI2 (203-206)3H3 (250-252)AH4 (253-268)AH3 (229-244)Updating...
connected with : NaN
molecule tags Cell cycle
source organism Homo sapiens
publication title 8-Substituted O6-Cyclohexylmethylguanine Cdk2 Inhibitors; Using Structure-Based Inhibitor Design to Optimise an Alternative Binding Mode.
pubmed doi rcsb
molecule keywords CYCLIN-DEPENDENT KINASE 2
total genus 93
structure length 258
sequence length 258
chains with identical sequence D
ec nomenclature
pdb deposition date 2013-11-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00134 Cyclin_N Cyclin, N-terminal domain
B PF02984 Cyclin_C Cyclin, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.472.10 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin-like 4cfmB01
1.10.472.10 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin-like 4cfmB02
1BU2A 2JGZB 4OGRB 4BCOB 4ELLA 1H1SB 5LQFB 5ACBA 2WIHB 2UUEB 3EIDB 5L2WB 2C5VB 5I5ZB 2BPMB 3QHWB 2IW6B 2UZDB 4CFUB 5IDPB 1W98B 4KRDB 4F7NB 5FGKB 4BCIB 1O9KA 3BLQB 4EOIB 3EOCB 3TNIB 1D3UB 1GUXB 1AD6A 2G9XB 4EOSB 1PKDB 4Y72B 4F70B 2WMAB 3BHVB 4F6WB 4BCQB 2I53A 2R7GA 2WIPB 2C5XB 1OI9B 2WEVB 1UNLD 4CFUD 2WFYB 1H4LD 4ELJA 3O0GD 1FINB 3BHUB 2PHGA 1VOLA 1OKVB 5HQ0B 1P5EB 3TNWB 4F6UB 1OIYB 2IW8B 1OL2B 1ZP2A 3TN8B 5ICPB 3MY1B 4YOSA 4CFWB 2UZLB 4YOOA 4EOLB 4F6SB 4BCQD 1H1PB 4BCMD 4EOPB 2C4GB 4CXAB 3BHTB 1H27B 4EC9B 4CFMB 4EOKB 4YOZA 3BLHB 4F7LB 1UNHD 3K7AM 4EOQB 5HNBB 1URCB 4BCGB 2V22B 4BCMB 5EFQB 2W9ZA 1OIUB 3DOGB 2PMIB 3BLRB 4YC3B 5LMKB 4BCKB 2PK9B 2C5OB 1H1QB 2WHBB 3H4CA 5BNJB 3DDPB 3POMA 5IDNB 4OR5B 1XO2A 2WPAB 4BCNB 5HVYB 1H26B 1C9BA 2B9RA 1F5QB 2UZEB 3G33B 4CFXB 1QMZB 3DDQB 3MY5B 1JSUB 2IVXA 4EORB 4EC8B 2CCIB 4BCFB 1H24B 4EOOB 2W2HA 4ROCA 3F5XB 1VINA 2EUFA 4FX3B 2F2CA 4I3ZB 1O9KB 3RGFB 4BCND 4II5B 2W9FA 1JOWA 3MIAB 1UNGD 1H1RB 4G6LB 4IMYB 1VYWB 2X1NB 5HBEB 1AISB 5CYIB 1OGUB 1G3NC 4EOMB 2PK2A 1JKWA 2CCHB 2C5NB 2I40B 3LQ5B 1GH6B 4F7JB 1OKWB 1GUXA 4BCJB 4TTHA 2BKZB 1H25B 3MI9B 4EONB 2IW9B 2UZBB 3QHRB 2W99A 2CJMB 4CFNB 4RODA 4BCHB 4BCPB 1GY3B 1FVVB 1N4MA 2W96A 4UN0A 4EOJB 4KRCB 1H28B 1E9HB 5IF1B 5HBHB 4NSTB 1JSTB 2WMBB 3M03A 5CEIB 1TFBA 1KXUA 4F7SB 2QDJA 3EJ1B 2C6TB 3TNHB 2WXVB 4CFVB 4CRLB 4ROEA 5HBJB 1OL1B
chains in the Genus database with same CATH superfamily
1BU2A 2JGZB 4OGRB 2QDYB 5LQFB 2BPMB 5IDPB 1W98B 1FKMA 4ZGDB 3X24B 1GUXB 2G9XB 2QF7A 2PJQA 1PKDB 4Y72B 4F70B 3BHVB 2DXBB 4BCQB 2ZPGB 2WIPB 3A8HB 4JX6A 2WEVB 4OB0B 4CFUD 2CYZB 4ELJA 2D0QB 2PHGA 4BBRM 1P5EB 1OIYB 5DQWA 1AHJB 4CFWB 3WVEB 4EOLB 2DPPB 4EOPB 4EC9B 4JX5A 4F7LB 1UNHD 2KMGA 4BCMB 2W9ZA 3DOGB 1V29B 3QYEA 4BCKB 3POMA 4BCNB 1XO2A 1H26B 1C9BA 1F5QB 3DDQB 4BXXX 2CCIB 4AKHA 4HNVA 4OB2B 2G77A 2EUFA 4AI6A 5DQVA 3RGFB 3BG5A 2CZ6B 1JOWA 3MIAB 4IMYB 1VYWB 2X1NB 3VYGB 1G3NC 4M6VA 3QYHB 1UGSB 4F7JB 2WJ9A 2BKZB 2BS2A 3VKGA 4RODA 2W96A 4UN0A 3KHIA 3VYHB 4KRCB 1H28B 5CEIB 2WIHB 2UUEB 2ZPFB 2DMEA 4KRDB 1O9KA 3BLQB 1D3UB 4BY1X 2WMAB 3HB9A 4HL4A 1OI9B 1UNLD 4Z6YA 2CZ7B 4QSHA 1VOLA 1OKVB 5HQ0B 3TNWB 4F6UB 3MY1B 3QZ9B 4YOSA 4F6SB 4YOOA 4BCMD 1H27B 4EOKB 4BCGB 3QZ5B 2PMIB 3BLRB 4BBSM 2PK9B 3A8GB 2AHJB 4HNTA 4EORB 4BCFB 1UGPB 3X26B 2CZ0B 2W2HA 4HLQA 4ROCA 3DL1A 2F2CA 4I3ZB 1UGRB 1UNGD 1AISB 5HBEB 5CYIB 1OGUB 4AKIA 1JKWA 3MI9B 2CJMB 3BG9A 2QFZA 3DJBA 3BG3A 4BCHB 4EOJB 5HBHB 4F7SB 3EJ1B 3TNHB 4FM4B 4ROEA 4BCOB 2QGSA 5IHYA 5L2WB 5I5ZB 2IW6B 4MIMA 2UZDB 4CFUB 4ZGEB 5FGKB 4BCIB 3EOCB 3TNIB 4MFEA 3HZJA 3GTMS 1ENWA 2R7GA 2C5XB 2WFYB 1H4LD 2BS4A 3O0GD 1FINB 3BHUB 3TW6A 1OL2B 5ICPB 4BCQD 2C4GB 2KR6A 4CFMB 4YOZA 3K7AM 3NDQA 3HBLA 5EFQB 1OIUB 5LMKB 2WHBB 5BNJB 3DDPB 4OR5B 2IN3A 3B57A 5HVYB 4OB3B 2B9RA 3G33B 4CFXB 3QYBA 2ZPEB 2BS3A 2DD4B 2ZPBB 1H24B 2ZPHB 3F5XB 1VINA 4FX3B 1UGQB 1O9KB 4BCND 2LW4A 3VKHA 3PO3S 3DTOA 2C5NB 1QLBA 2I40B 1GH6B 1OKWB 4BCJB 4TTHA 4JX4A 4EONB 2IW9B 4BCPB 4BY7X 4MFDA 3X20B 4AKGA 1E9HB 4NSTB 2WMBB 1TFBA 4CFVB 4CRLB 5HBJB 4ELLA 1H1SB 5ACBA 4LOCA 3EIDB 3QYGB 2C5VB 3QHWB 4F7NB 4EOIB 3QXEB 1AD6A 4EOSB 2DXCB 4HNUA 2ZZDB 4F6WB 2I53A 3A8MB 3A8OB 2IW8B 1ZP2A 3TN8B 2UZLB 1H1PB 4CXAB 3BHTB 1IREB 3A8LB 3HO8A 3BLHB 4EOQB 5HNBB 1URCB 2V22B 4YC3B 3TW7A 2C5OB 1H1QB 3H4CA 5IDNB 2WPAB 2UZEB 1QMZB 3MY5B 4OB1B 1JSUB 2IVXA 4EC8B 3QWLA 3WVDB 4EOOB 2DD5B 3HHTB 4II5B 2W9FA 4G6LB 1H1RB 2QQ8A 2CZ1B 1E7PA 4EOMB 2PK2A 2CCHB 3LQ5B 1GUXA 3X28B 3X25B 1H25B 2UZBB 1TD6A 3QHRB 2W99A 2ZPIB 4CFNB 1GY3B 1FVVB 1N4MA 4NC6A 5IF1B 2ZCFB 1JSTB 3M03A 1KXUA 4ZGJB 2QDJA 2C6TB 2WXVB 5EJCA 1OL1B
chains in the Genus database with same CATH topology
1BU2A 2JGZB 4OGRB 4BCOB 4ELLA 1H1SB 5LQFB 5ACBA 2WIHB 2UUEB 3EIDB 5L2WB 2C5VB 5I5ZB 2BPMB 3QHWB 2IW6B 2UZDB 4CFUB 5IDPB 1W98B 4KRDB 4F7NB 5FGKB 4BCIB 1O9KA 3BLQB 4EOIB 3EOCB 3TNIB 1D3UB 1GUXB 1AD6A 2G9XB 4EOSB 1PKDB 4Y72B 4F70B 2WMAB 3BHVB 4F6WB 4BCQB 2I53A 2R7GA 2WIPB 2C5XB 1OI9B 2WEVB 1UNLD 4CFUD 2WFYB 1H4LD 4ELJA 3O0GD 1FINB 3BHUB 2PHGA 1VOLA 1OKVB 5HQ0B 1P5EB 3TNWB 4F6UB 1OIYB 2IW8B 1OL2B 1ZP2A 3TN8B 5ICPB 3MY1B 4YOSA 4CFWB 2UZLB 4YOOA 4EOLB 4F6SB 4BCQD 1H1PB 4BCMD 4EOPB 2C4GB 4CXAB 3BHTB 1H27B 4EC9B 4CFMB 4EOKB 4YOZA 3BLHB 4F7LB 1UNHD 3K7AM 4EOQB 5HNBB 1URCB 4BCGB 2V22B 4BCMB 5EFQB 2W9ZA 1OIUB 3DOGB 2PMIB 3BLRB 4YC3B 5LMKB 4BCKB 2PK9B 2C5OB 1H1QB 2WHBB 3H4CA 5BNJB 3DDPB 3POMA 5IDNB 4OR5B 1XO2A 2WPAB 4BCNB 5HVYB 1H26B 1C9BA 2B9RA 1F5QB 2UZEB 3G33B 4CFXB 1QMZB 3DDQB 3MY5B 1JSUB 2IVXA 4EORB 4EC8B 2CCIB 4BCFB 1H24B 4EOOB 2W2HA 4ROCA 3F5XB 1VINA 2EUFA 4FX3B 2F2CA 4I3ZB 1O9KB 3RGFB 4BCND 4II5B 2W9FA 1JOWA 3MIAB 1UNGD 1H1RB 4G6LB 4IMYB 1VYWB 2X1NB 5HBEB 1AISB 5CYIB 1OGUB 1G3NC 4EOMB 2PK2A 1JKWA 2CCHB 2C5NB 2I40B 3LQ5B 1GH6B 4F7JB 1OKWB 1GUXA 4BCJB 4TTHA 2BKZB 1H25B 3MI9B 4EONB 2IW9B 2UZBB 3QHRB 2W99A 2CJMB 4CFNB 4RODA 4BCHB 4BCPB 1GY3B 1FVVB 1N4MA 2W96A 4UN0A 4EOJB 4KRCB 1H28B 1E9HB 5IF1B 5HBHB 4NSTB 1JSTB 2WMBB 3M03A 5CEIB 1TFBA 1KXUA 4F7SB 2QDJA 3EJ1B 2C6TB 3TNHB 2WXVB 4CFVB 4CRLB 4ROEA 5HBJB 1OL1B
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1BU2 A;  2JGZ B;  4OGR B;  4BCO B;  4ELL A;  1H1S B;  5LQF B;  5ACB A;  2WIH B;  2UUE B;  3EID B;  5L2W B;  2C5V B;  5I5Z B;  2BPM B;  3QHW B;  2IW6 B;  2UZD B;  4CFU B;  5IDP B;  1W98 B;  4KRD B;  4F7N B;  5FGK B;  4BCI B;  1O9K A;  3BLQ B;  4EOI B;  3EOC B;  3TNI B;  1D3U B;  1GUX B;  1AD6 A;  2G9X B;  4EOS B;  1PKD B;  4Y72 B;  4F70 B;  2WMA B;  3BHV B;  4F6W B;  4BCQ B;  2I53 A;  2R7G A;  2WIP B;  2C5X B;  1OI9 B;  2WEV B;  1UNL D;  4CFU D;  2WFY B;  1H4L D;  4ELJ A;  3O0G D;  1FIN B;  3BHU B;  2PHG A;  1VOL A;  1OKV B;  5HQ0 B;  1P5E B;  3TNW B;  4F6U B;  1OIY B;  2IW8 B;  1OL2 B;  1ZP2 A;  3TN8 B;  5ICP B;  3MY1 B;  4YOS A;  4CFW B;  2UZL B;  4YOO A;  4EOL B;  4F6S B;  4BCQ D;  1H1P B;  4BCM D;  4EOP B;  2C4G B;  4CXA B;  3BHT B;  1H27 B;  4EC9 B;  4CFM B;  4EOK B;  4YOZ A;  3BLH B;  4F7L B;  1UNH D;  3K7A M;  4EOQ B;  5HNB B;  1URC B;  4BCG B;  2V22 B;  4BCM B;  5EFQ B;  2W9Z A;  1OIU B;  3DOG B;  2PMI B;  3BLR B;  4YC3 B;  5LMK B;  4BCK B;  2PK9 B;  2C5O B;  1H1Q B;  2WHB B;  3H4C A;  5BNJ B;  3DDP B;  3POM A;  5IDN B;  4OR5 B;  1XO2 A;  2WPA B;  4BCN B;  5HVY B;  1H26 B;  1C9B A;  2B9R A;  1F5Q B;  2UZE B;  3G33 B;  4CFX B;  1QMZ B;  3DDQ B;  3MY5 B;  1JSU B;  2IVX A;  4EOR B;  4EC8 B;  2CCI B;  4BCF B;  1H24 B;  4EOO B;  2W2H A;  4ROC A;  3F5X B;  1VIN A;  2EUF A;  4FX3 B;  2F2C A;  4I3Z B;  1O9K B;  3RGF B;  4BCN D;  4II5 B;  2W9F A;  1JOW A;  3MIA B;  1UNG D;  1H1R B;  4G6L B;  4IMY B;  1VYW B;  2X1N B;  5HBE B;  1AIS B;  5CYI B;  1OGU B;  1G3N C;  4EOM B;  2PK2 A;  1JKW A;  2CCH B;  2C5N B;  2I40 B;  3LQ5 B;  1GH6 B;  4F7J B;  1OKW B;  1GUX A;  4BCJ B;  4TTH A;  2BKZ B;  1H25 B;  3MI9 B;  4EON B;  2IW9 B;  2UZB B;  3QHR B;  2W99 A;  2CJM B;  4CFN B;  4ROD A;  4BCH B;  4BCP B;  1GY3 B;  1FVV B;  1N4M A;  2W96 A;  4UN0 A;  4EOJ B;  4KRC B;  1H28 B;  1E9H B;  5IF1 B;  5HBH B;  4NST B;  1JST B;  2WMB B;  3M03 A;  5CEI B;  1TFB A;  1KXU A;  4F7S B;  2QDJ A;  3EJ1 B;  2C6T B;  3TNH B;  2WXV B;  4CFV B;  4CRL B;  4ROE A;  5HBJ B;  1OL1 B; 
#chains in the Genus database with same CATH topology
 1BU2 A;  2JGZ B;  4OGR B;  2QDY B;  5LQF B;  2BPM B;  5IDP B;  1W98 B;  1FKM A;  4ZGD B;  3X24 B;  1GUX B;  2G9X B;  2QF7 A;  2PJQ A;  1PKD B;  4Y72 B;  4F70 B;  3BHV B;  2DXB B;  4BCQ B;  2ZPG B;  2WIP B;  3A8H B;  4JX6 A;  2WEV B;  4OB0 B;  4CFU D;  2CYZ B;  4ELJ A;  2D0Q B;  2PHG A;  4BBR M;  1P5E B;  1OIY B;  5DQW A;  1AHJ B;  4CFW B;  3WVE B;  4EOL B;  2DPP B;  4EOP B;  4EC9 B;  4JX5 A;  4F7L B;  1UNH D;  2KMG A;  4BCM B;  2W9Z A;  3DOG B;  1V29 B;  3QYE A;  4BCK B;  3POM A;  4BCN B;  1XO2 A;  1H26 B;  1C9B A;  1F5Q B;  3DDQ B;  4BXX X;  2CCI B;  4AKH A;  4HNV A;  4OB2 B;  2G77 A;  2EUF A;  4AI6 A;  5DQV A;  3RGF B;  3BG5 A;  2CZ6 B;  1JOW A;  3MIA B;  4IMY B;  1VYW B;  2X1N B;  3VYG B;  1G3N C;  4M6V A;  3QYH B;  1UGS B;  4F7J B;  2WJ9 A;  2BKZ B;  2BS2 A;  3VKG A;  4ROD A;  2W96 A;  4UN0 A;  3KHI A;  3VYH B;  4KRC B;  1H28 B;  5CEI B;  2WIH B;  2UUE B;  2ZPF B;  2DME A;  4KRD B;  1O9K A;  3BLQ B;  1D3U B;  4BY1 X;  2WMA B;  3HB9 A;  4HL4 A;  1OI9 B;  1UNL D;  4Z6Y A;  2CZ7 B;  4QSH A;  1VOL A;  1OKV B;  5HQ0 B;  3TNW B;  4F6U B;  3MY1 B;  3QZ9 B;  4YOS A;  4F6S B;  4YOO A;  4BCM D;  1H27 B;  4EOK B;  4BCG B;  3QZ5 B;  2PMI B;  3BLR B;  4BBS M;  2PK9 B;  3A8G B;  2AHJ B;  4HNT A;  4EOR B;  4BCF B;  1UGP B;  3X26 B;  2CZ0 B;  2W2H A;  4HLQ A;  4ROC A;  3DL1 A;  2F2C A;  4I3Z B;  1UGR B;  1UNG D;  1AIS B;  5HBE B;  5CYI B;  1OGU B;  4AKI A;  1JKW A;  3MI9 B;  2CJM B;  3BG9 A;  2QFZ A;  3DJB A;  3BG3 A;  4BCH B;  4EOJ B;  5HBH B;  4F7S B;  3EJ1 B;  3TNH B;  4FM4 B;  4ROE A;  4BCO B;  2QGS A;  5IHY A;  5L2W B;  5I5Z B;  2IW6 B;  4MIM A;  2UZD B;  4CFU B;  4ZGE B;  5FGK B;  4BCI B;  3EOC B;  3TNI B;  4MFE A;  3HZJ A;  3GTM S;  1ENW A;  2R7G A;  2C5X B;  2WFY B;  1H4L D;  2BS4 A;  3O0G D;  1FIN B;  3BHU B;  3TW6 A;  1OL2 B;  5ICP B;  4BCQ D;  2C4G B;  2KR6 A;  4CFM B;  4YOZ A;  3K7A M;  3NDQ A;  3HBL A;  5EFQ B;  1OIU B;  5LMK B;  2WHB B;  5BNJ B;  3DDP B;  4OR5 B;  2IN3 A;  3B57 A;  5HVY B;  4OB3 B;  2B9R A;  3G33 B;  4CFX B;  3QYB A;  2ZPE B;  2BS3 A;  2DD4 B;  2ZPB B;  1H24 B;  2ZPH B;  3F5X B;  1VIN A;  4FX3 B;  1UGQ B;  1O9K B;  4BCN D;  2LW4 A;  3VKH A;  3PO3 S;  3DTO A;  2C5N B;  1QLB A;  2I40 B;  1GH6 B;  1OKW B;  4BCJ B;  4TTH A;  4JX4 A;  4EON B;  2IW9 B;  4BCP B;  4BY7 X;  4MFD A;  3X20 B;  4AKG A;  1E9H B;  4NST B;  2WMB B;  1TFB A;  4CFV B;  4CRL B;  5HBJ B;  4ELL A;  1H1S B;  5ACB A;  4LOC A;  3EID B;  3QYG B;  2C5V B;  3QHW B;  4F7N B;  4EOI B;  3QXE B;  1AD6 A;  4EOS B;  2DXC B;  4HNU A;  2ZZD B;  4F6W B;  2I53 A;  3A8M B;  3A8O B;  2IW8 B;  1ZP2 A;  3TN8 B;  2UZL B;  1H1P B;  4CXA B;  3BHT B;  1IRE B;  3A8L B;  3HO8 A;  3BLH B;  4EOQ B;  5HNB B;  1URC B;  2V22 B;  4YC3 B;  3TW7 A;  2C5O B;  1H1Q B;  3H4C A;  5IDN B;  2WPA B;  2UZE B;  1QMZ B;  3MY5 B;  4OB1 B;  1JSU B;  2IVX A;  4EC8 B;  3QWL A;  3WVD B;  4EOO B;  2DD5 B;  3HHT B;  4II5 B;  2W9F A;  4G6L B;  1H1R B;  2QQ8 A;  2CZ1 B;  1E7P A;  4EOM B;  2PK2 A;  2CCH B;  3LQ5 B;  1GUX A;  3X28 B;  3X25 B;  1H25 B;  2UZB B;  1TD6 A;  3QHR B;  2W99 A;  2ZPI B;  4CFN B;  1GY3 B;  1FVV B;  1N4M A;  4NC6 A;  5IF1 B;  2ZCF B;  1JST B;  3M03 A;  1KXU A;  4ZGJ B;  2QDJ A;  2C6T B;  2WXV B;  5EJC A;  1OL1 B; 
#chains in the Genus database with same CATH homology
 1BU2 A;  2JGZ B;  4OGR B;  4BCO B;  4ELL A;  1H1S B;  5LQF B;  5ACB A;  2WIH B;  2UUE B;  3EID B;  5L2W B;  2C5V B;  5I5Z B;  2BPM B;  3QHW B;  2IW6 B;  2UZD B;  4CFU B;  5IDP B;  1W98 B;  4KRD B;  4F7N B;  5FGK B;  4BCI B;  1O9K A;  3BLQ B;  4EOI B;  3EOC B;  3TNI B;  1D3U B;  1GUX B;  1AD6 A;  2G9X B;  4EOS B;  1PKD B;  4Y72 B;  4F70 B;  2WMA B;  3BHV B;  4F6W B;  4BCQ B;  2I53 A;  2R7G A;  2WIP B;  2C5X B;  1OI9 B;  2WEV B;  1UNL D;  4CFU D;  2WFY B;  1H4L D;  4ELJ A;  3O0G D;  1FIN B;  3BHU B;  2PHG A;  1VOL A;  1OKV B;  5HQ0 B;  1P5E B;  3TNW B;  4F6U B;  1OIY B;  2IW8 B;  1OL2 B;  1ZP2 A;  3TN8 B;  5ICP B;  3MY1 B;  4YOS A;  4CFW B;  2UZL B;  4YOO A;  4EOL B;  4F6S B;  4BCQ D;  1H1P B;  4BCM D;  4EOP B;  2C4G B;  4CXA B;  3BHT B;  1H27 B;  4EC9 B;  4CFM B;  4EOK B;  4YOZ A;  3BLH B;  4F7L B;  1UNH D;  3K7A M;  4EOQ B;  5HNB B;  1URC B;  4BCG B;  2V22 B;  4BCM B;  5EFQ B;  2W9Z A;  1OIU B;  3DOG B;  2PMI B;  3BLR B;  4YC3 B;  5LMK B;  4BCK B;  2PK9 B;  2C5O B;  1H1Q B;  2WHB B;  3H4C A;  5BNJ B;  3DDP B;  3POM A;  5IDN B;  4OR5 B;  1XO2 A;  2WPA B;  4BCN B;  5HVY B;  1H26 B;  1C9B A;  2B9R A;  1F5Q B;  2UZE B;  3G33 B;  4CFX B;  1QMZ B;  3DDQ B;  3MY5 B;  1JSU B;  2IVX A;  4EOR B;  4EC8 B;  2CCI B;  4BCF B;  1H24 B;  4EOO B;  2W2H A;  4ROC A;  3F5X B;  1VIN A;  2EUF A;  4FX3 B;  2F2C A;  4I3Z B;  1O9K B;  3RGF B;  4BCN D;  4II5 B;  2W9F A;  1JOW A;  3MIA B;  1UNG D;  1H1R B;  4G6L B;  4IMY B;  1VYW B;  2X1N B;  5HBE B;  1AIS B;  5CYI B;  1OGU B;  1G3N C;  4EOM B;  2PK2 A;  1JKW A;  2CCH B;  2C5N B;  2I40 B;  3LQ5 B;  1GH6 B;  4F7J B;  1OKW B;  1GUX A;  4BCJ B;  4TTH A;  2BKZ B;  1H25 B;  3MI9 B;  4EON B;  2IW9 B;  2UZB B;  3QHR B;  2W99 A;  2CJM B;  4CFN B;  4ROD A;  4BCH B;  4BCP B;  1GY3 B;  1FVV B;  1N4M A;  2W96 A;  4UN0 A;  4EOJ B;  4KRC B;  1H28 B;  1E9H B;  5IF1 B;  5HBH B;  4NST B;  1JST B;  2WMB B;  3M03 A;  5CEI B;  1TFB A;  1KXU A;  4F7S B;  2QDJ A;  3EJ1 B;  2C6T B;  3TNH B;  2WXV B;  4CFV B;  4CRL B;  4ROE A;  5HBJ B;  1OL1 B;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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