4F6UB

Crystal structure of human cdk8/cycc in complex with compound 5 (1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-[3-(morpholin-4-yl)propyl]urea)
Total Genus 98

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
267
structure length
267
Chain Sequence
DKAMAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDARQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKMPKPKPPP

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
TII1 (-1-2)AH8 (155-166)3H1 (5-7)TI1 (1-4)AH1 (9-14)3H2 (188-190)AH2 (18-30)TI2 (77-80)EMPTYTIV1 (78-81)AH3 (34-55)AH4 (59-75)TVIII1 (79-82)AH5 (83-98)AH10 (194-209)AH12 (224-243)AH11 (213-219)AH13 (246-256)AH7 (132-146)TI'1 (146-149)TI3 (120-123)AH6 (105-120)AH9 (169-184)Updating...
connected with : NaN
molecule tags Transferase/transcription/inhibitor
source organism Homo sapiens
publication title Structure-kinetic relationship study of CDK8/CycC specific compounds.
pubmed doi rcsb
molecule keywords Cyclin-dependent kinase 8
total genus 98
structure length 267
sequence length 267
ec nomenclature
pdb deposition date 2012-05-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00134 Cyclin_N Cyclin, N-terminal domain
B PF16899 Cyclin_C_2 Cyclin C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.472.10 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin-like 4f6uB02
1.10.472.10 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin-like 4f6uB01
3EIDB 3K7AM 1W98B 2IW8B 1PKDB 1OL2B 2B9RA 2CCIB 3MIAB 4BCND 1VOLA 2C5XB 2UZDB 1N4MA 1H24B 2IVXA 3O0GD 4CXAB 2UZBB 3BHTB 2W2HA 3BLRB 4KRDB 4BCKB 1GUXB 2WPAB 1UNLD 1ZP2A 3DDPB 4BCHB 4CFMB 4EONB 5LMKB 2WIHB 4YOZA 1OKWB 1FVVB 1O9KA 4EORB 1OGUB 2I40B 1H1RB 4F7SB 1JKWA 3M03A 4IMYB 5LQFB 1UNHD 4EOJB 3LQ5B 3TN8B 2WMBB 5HBEB 4EOKB 1H1SB 1G3NC 4OR5B 4BCPB 2F2CA 1FINB 1AD6A 5HVYB 3QHRB 4ROCA 2C4GB 1BU2A 4BCGB 1P5EB 1JSUB 2G9XB 1OI9B 4EC8B 2BPMB 4EOPB 2C6TB 1H28B 2W96A 5FGKB 4BCFB 1JOWA 3EJ1B 3BLQB 4ROEA 4EOSB 1OIYB 4CRLB 1VINA 1GY3B 1JSTB 4YC3B 5EFQB 2UUEB 1KXUA 3QHWB 3TNHB 3MI9B 4CFXB 4BCMB 5CYIB 3BLHB 2EUFA 4Y72B 2X1NB 4FX3B 4BCQB 2CJMB 2PMIB 3G33B 3POMA 3RGFB 2C5OB 1URCB 2WXVB 4F6SB 4CFNB 1H26B 2BKZB 5ACBA 5BNJB 4I3ZB 1GUXA 4YOSA 2W9FA 3TNWB 3DDQB 4RODA 5IDNB 3F5XB 2PHGA 2JGZB 2WHBB 5HBHB 1F5QB 5IF1B 2W9ZA 1VYWB 3EOCB 4EOLB 4BCQD 1H25B 1OL1B 1C9BA 4ELJA 3BHVB 3DOGB 5I5ZB 2QDJA 4F70B 2UZEB 1O9KB 2I53A 1XO2A 1GH6B 4EC9B 2UZLB 3TNIB 1OKVB 1H27B 1H1PB 1UNGD 4CFVB 3MY1B 4G6LB 4CFUB 1OIUB 4F7LB 2PK2A 2WMAB 3MY5B 2R7GA 5L2WB 4EOIB 4NSTB 2PK9B 4EOQB 4KRCB 4BCOB 1H4LD 1TFBA 5HNBB 2IW6B 4F6WB 4F7JB 4UN0A 3H4CA 1H1QB 5HQ0B 2WIPB 4BCJB 5ICPB 4YOOA 4BCMD 4ELLA 4BCNB 4OGRB 2C5NB 2WFYB 5CEIB 2V22B 3BHUB 5HBJB 4EOOB 2IW9B 4CFUD 1D3UB 4CFWB 1QMZB 2C5VB 4F7NB 2WEVB 5IDPB 4TTHA 1AISB 2CCHB 2W99A 4II5B 4BCIB 1E9HB 4EOMB 4F6UB
chains in the Genus database with same CATH superfamily
2QGSA 2ZCFB 4BCND 1VOLA 3TW6A 1H24B 3BHTB 4AKIA 3B57A 4EONB 4EORB 1O9KA 1H1RB 4JX5A 1JKWA 1UNHD 3LQ5B 5HBEB 2F2CA 4ROCA 5HVYB 2KR6A 1OI9B 5FGKB 3HZJA 2UUEB 4ZGDB 3TNHB 3BLHB 4BBRM 4HLQA 4OB0B 4FX3B 2PMIB 3POMA 2WXVB 4CFNB 1H26B 4I3ZB 2BS3A 3A8MB 2QF7A 3QYGB 4JX4A 2PHGA 2WHBB 1IREB 2BS2A 4AI6A 1H25B 4MFEA 1C9BA 2ZPEB 2UZEB 1O9KB 4HNTA 1UNGD 1H1PB 3WVDB 4F7LB 3MY5B 3X24B 2ZPGB 4NSTB 1ENWA 3GTMS 1TFBA 4F6WB 3BG9A 4F7JB 3QZ5B 4BCMD 3VYGB 3QXEB 4CFWB 3BG5A 1AISB 2CCHB 4II5B 1E9HB 4EOMB 4F6UB 2AHJB 2IW8B 2WJ9A 1PKDB 1OL2B 2B9RA 3X20B 2IVXA 3O0GD 3TW7A 2UZBB 2DMEA 3BLRB 2WPAB 3DDPB 1ZP2A 5LMKB 2WIHB 4YOZA 1FVVB 1FKMA 4F7SB 4BY7X 3M03A 5LQFB 5EJCA 4EOJB 4EOKB 4BCPB 4FM4B 2QQ8A 3X28B 2ZPFB 1AD6A 2C4GB 1P5EB 1H28B 4EOSB 1OIYB 4CRLB 1VINA 4YC3B 4LOCA 5IHYA 1KXUA 3QHWB 3MI9B 2X1NB 2ZPHB 4BBSM 2LW4A 3G33B 3RGFB 1URCB 2IN3A 3HO8A 3TNWB 3DDQB 3X26B 1F5QB 1VYWB 3EOCB 1OL1B 4MIMA 4ELJA 3DOGB 3QYEA 1XO2A 1GH6B 2UZLB 2BS4A 2DD4B 3QYBA 1V29B 3DJBA 2DPPB 2WMAB 2R7GA 5L2WB 2PK9B 4EOQB 4BCOB 4NC6A 1H4LD 5HNBB 3HB9A 4UN0A 2ZPBB 4BCJB 2CZ0B 5CEIB 2C5NB 5HBJB 2ZZDB 1D3UB 1QMZB 2C5VB 4F7NB 5IDPB 4M6VA 1TD6A 3EIDB 3K7AM 3A8LB 1W98B 3PO3S 3VKGA 4CXAB 4AKHA 2W2HA 4HL4A 4BCHB 4BCKB 1UGPB 4CFMB 1UNLD 2QDYB 1OKWB 2D0QB 4OB1B 2I40B 1UGQB 4IMYB 3TN8B 1H1SB 3A8GB 4OR5B 3QWLA 4BCGB 2CZ7B 4EC8B 4EOPB 1JOWA 3EJ1B 3BG3A 2DXBB 4JX6A 5EFQB 2G77A 2DD5B 2EUFA 4Y72B 2CZ6B 3DL1A 4BCQB 1UGSB 2BKZB 5ACBA 1GUXA 3VYHB 4ZGEB 2KMGA 4OB3B 5HBHB 4ZGJB 5IF1B 2W9ZA 4BCQD 4QSHA 3BHVB 2QDJA 3DTOA 4EC9B 4CFVB 3MY1B 4EOIB 4KRCB 3H4CA 4MFDA 1H1QB 2WIPB 3HBLA 3VKHA 4ELLA 2PJQA 3BHUB 4EOOB 5DQVA 4TTHA 2W99A 4BCIB 1AHJB 4BXXX 3MIAB 2CCIB 2C5XB 2UZDB 1N4MA 4BY1X 3QZ9B 1E7PA 4KRDB 1GUXB 3NDQA 2QFZA 1OGUB 4Z6YA 2WMBB 1G3NC 1FINB 1BU2A 1JSUB 2G9XB 2BPMB 2C6TB 2W96A 4BCFB 4ROEA 3BLQB 3KHIA 1GY3B 1JSTB 1QLBA 3A8HB 4CFXB 4BCMB 2DXCB 5CYIB 3WVEB 2CJMB 2C5OB 4F6SB 5BNJB 4YOSA 2W9FA 4RODA 5IDNB 3F5XB 3QYHB 2JGZB 3HHTB 2CYZB 4EOLB 5I5ZB 4AKGA 3A8OB 4F70B 2I53A 5DQWA 3TNIB 1OKVB 1H27B 4G6LB 4CFUB 1OIUB 2ZPIB 2PK2A 4HNVA 3X25B 2IW6B 2CZ1B 5HQ0B 1UGRB 5ICPB 4YOOA 4OB2B 4BCNB 4OGRB 4HNUA 2WFYB 2V22B 2IW9B 4CFUD 2WEVB 3QHRB
chains in the Genus database with same CATH topology
3EIDB 3K7AM 1W98B 2IW8B 1PKDB 1OL2B 2B9RA 2CCIB 3MIAB 4BCND 1VOLA 2C5XB 2UZDB 1N4MA 1H24B 2IVXA 3O0GD 4CXAB 2UZBB 3BHTB 2W2HA 3BLRB 4KRDB 4BCKB 1GUXB 2WPAB 1UNLD 1ZP2A 3DDPB 4BCHB 4CFMB 4EONB 5LMKB 2WIHB 4YOZA 1OKWB 1FVVB 1O9KA 4EORB 1OGUB 2I40B 1H1RB 4F7SB 1JKWA 3M03A 4IMYB 5LQFB 1UNHD 4EOJB 3LQ5B 3TN8B 2WMBB 5HBEB 4EOKB 1H1SB 1G3NC 4OR5B 4BCPB 2F2CA 1FINB 1AD6A 5HVYB 3QHRB 4ROCA 2C4GB 1BU2A 4BCGB 1P5EB 1JSUB 2G9XB 1OI9B 4EC8B 2BPMB 4EOPB 2C6TB 1H28B 2W96A 5FGKB 4BCFB 1JOWA 3EJ1B 3BLQB 4ROEA 4EOSB 1OIYB 4CRLB 1VINA 1GY3B 1JSTB 4YC3B 5EFQB 2UUEB 1KXUA 3QHWB 3TNHB 3MI9B 4CFXB 4BCMB 5CYIB 3BLHB 2EUFA 4Y72B 2X1NB 4FX3B 4BCQB 2CJMB 2PMIB 3G33B 3POMA 3RGFB 2C5OB 1URCB 2WXVB 4F6SB 4CFNB 1H26B 2BKZB 5ACBA 5BNJB 4I3ZB 1GUXA 4YOSA 2W9FA 3TNWB 3DDQB 4RODA 5IDNB 3F5XB 2PHGA 2JGZB 2WHBB 5HBHB 1F5QB 5IF1B 2W9ZA 1VYWB 3EOCB 4EOLB 4BCQD 1H25B 1OL1B 1C9BA 4ELJA 3BHVB 3DOGB 5I5ZB 2QDJA 4F70B 2UZEB 1O9KB 2I53A 1XO2A 1GH6B 4EC9B 2UZLB 3TNIB 1OKVB 1H27B 1H1PB 1UNGD 4CFVB 3MY1B 4G6LB 4CFUB 1OIUB 4F7LB 2PK2A 2WMAB 3MY5B 2R7GA 5L2WB 4EOIB 4NSTB 2PK9B 4EOQB 4KRCB 4BCOB 1H4LD 1TFBA 5HNBB 2IW6B 4F6WB 4F7JB 4UN0A 3H4CA 1H1QB 5HQ0B 2WIPB 4BCJB 5ICPB 4YOOA 4BCMD 4ELLA 4BCNB 4OGRB 2C5NB 2WFYB 5CEIB 2V22B 3BHUB 5HBJB 4EOOB 2IW9B 4CFUD 1D3UB 4CFWB 1QMZB 2C5VB 4F7NB 2WEVB 5IDPB 4TTHA 1AISB 2CCHB 2W99A 4II5B 4BCIB 1E9HB 4EOMB 4F6UB
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3EID B;  3K7A M;  1W98 B;  2IW8 B;  1PKD B;  1OL2 B;  2B9R A;  2CCI B;  3MIA B;  4BCN D;  1VOL A;  2C5X B;  2UZD B;  1N4M A;  1H24 B;  2IVX A;  3O0G D;  4CXA B;  2UZB B;  3BHT B;  2W2H A;  3BLR B;  4KRD B;  4BCK B;  1GUX B;  2WPA B;  1UNL D;  1ZP2 A;  3DDP B;  4BCH B;  4CFM B;  4EON B;  5LMK B;  2WIH B;  4YOZ A;  1OKW B;  1FVV B;  1O9K A;  4EOR B;  1OGU B;  2I40 B;  1H1R B;  4F7S B;  1JKW A;  3M03 A;  4IMY B;  5LQF B;  1UNH D;  4EOJ B;  3LQ5 B;  3TN8 B;  2WMB B;  5HBE B;  4EOK B;  1H1S B;  1G3N C;  4OR5 B;  4BCP B;  2F2C A;  1FIN B;  1AD6 A;  5HVY B;  3QHR B;  4ROC A;  2C4G B;  1BU2 A;  4BCG B;  1P5E B;  1JSU B;  2G9X B;  1OI9 B;  4EC8 B;  2BPM B;  4EOP B;  2C6T B;  1H28 B;  2W96 A;  5FGK B;  4BCF B;  1JOW A;  3EJ1 B;  3BLQ B;  4ROE A;  4EOS B;  1OIY B;  4CRL B;  1VIN A;  1GY3 B;  1JST B;  4YC3 B;  5EFQ B;  2UUE B;  1KXU A;  3QHW B;  3TNH B;  3MI9 B;  4CFX B;  4BCM B;  5CYI B;  3BLH B;  2EUF A;  4Y72 B;  2X1N B;  4FX3 B;  4BCQ B;  2CJM B;  2PMI B;  3G33 B;  3POM A;  3RGF B;  2C5O B;  1URC B;  2WXV B;  4F6S B;  4CFN B;  1H26 B;  2BKZ B;  5ACB A;  5BNJ B;  4I3Z B;  1GUX A;  4YOS A;  2W9F A;  3TNW B;  3DDQ B;  4ROD A;  5IDN B;  3F5X B;  2PHG A;  2JGZ B;  2WHB B;  5HBH B;  1F5Q B;  5IF1 B;  2W9Z A;  1VYW B;  3EOC B;  4EOL B;  4BCQ D;  1H25 B;  1OL1 B;  1C9B A;  4ELJ A;  3BHV B;  3DOG B;  5I5Z B;  2QDJ A;  4F70 B;  2UZE B;  1O9K B;  2I53 A;  1XO2 A;  1GH6 B;  4EC9 B;  2UZL B;  3TNI B;  1OKV B;  1H27 B;  1H1P B;  1UNG D;  4CFV B;  3MY1 B;  4G6L B;  4CFU B;  1OIU B;  4F7L B;  2PK2 A;  2WMA B;  3MY5 B;  2R7G A;  5L2W B;  4EOI B;  4NST B;  2PK9 B;  4EOQ B;  4KRC B;  4BCO B;  1H4L D;  1TFB A;  5HNB B;  2IW6 B;  4F6W B;  4F7J B;  4UN0 A;  3H4C A;  1H1Q B;  5HQ0 B;  2WIP B;  4BCJ B;  5ICP B;  4YOO A;  4BCM D;  4ELL A;  4BCN B;  4OGR B;  2C5N B;  2WFY B;  5CEI B;  2V22 B;  3BHU B;  5HBJ B;  4EOO B;  2IW9 B;  4CFU D;  1D3U B;  4CFW B;  1QMZ B;  2C5V B;  4F7N B;  2WEV B;  5IDP B;  4TTH A;  1AIS B;  2CCH B;  2W99 A;  4II5 B;  4BCI B;  1E9H B;  4EOM B;  4F6U B; 
#chains in the Genus database with same CATH topology
 2QGS A;  2ZCF B;  4BCN D;  1VOL A;  3TW6 A;  1H24 B;  3BHT B;  4AKI A;  3B57 A;  4EON B;  4EOR B;  1O9K A;  1H1R B;  4JX5 A;  1JKW A;  1UNH D;  3LQ5 B;  5HBE B;  2F2C A;  4ROC A;  5HVY B;  2KR6 A;  1OI9 B;  5FGK B;  3HZJ A;  2UUE B;  4ZGD B;  3TNH B;  3BLH B;  4BBR M;  4HLQ A;  4OB0 B;  4FX3 B;  2PMI B;  3POM A;  2WXV B;  4CFN B;  1H26 B;  4I3Z B;  2BS3 A;  3A8M B;  2QF7 A;  3QYG B;  4JX4 A;  2PHG A;  2WHB B;  1IRE B;  2BS2 A;  4AI6 A;  1H25 B;  4MFE A;  1C9B A;  2ZPE B;  2UZE B;  1O9K B;  4HNT A;  1UNG D;  1H1P B;  3WVD B;  4F7L B;  3MY5 B;  3X24 B;  2ZPG B;  4NST B;  1ENW A;  3GTM S;  1TFB A;  4F6W B;  3BG9 A;  4F7J B;  3QZ5 B;  4BCM D;  3VYG B;  3QXE B;  4CFW B;  3BG5 A;  1AIS B;  2CCH B;  4II5 B;  1E9H B;  4EOM B;  4F6U B;  2AHJ B;  2IW8 B;  2WJ9 A;  1PKD B;  1OL2 B;  2B9R A;  3X20 B;  2IVX A;  3O0G D;  3TW7 A;  2UZB B;  2DME A;  3BLR B;  2WPA B;  3DDP B;  1ZP2 A;  5LMK B;  2WIH B;  4YOZ A;  1FVV B;  1FKM A;  4F7S B;  4BY7 X;  3M03 A;  5LQF B;  5EJC A;  4EOJ B;  4EOK B;  4BCP B;  4FM4 B;  2QQ8 A;  3X28 B;  2ZPF B;  1AD6 A;  2C4G B;  1P5E B;  1H28 B;  4EOS B;  1OIY B;  4CRL B;  1VIN A;  4YC3 B;  4LOC A;  5IHY A;  1KXU A;  3QHW B;  3MI9 B;  2X1N B;  2ZPH B;  4BBS M;  2LW4 A;  3G33 B;  3RGF B;  1URC B;  2IN3 A;  3HO8 A;  3TNW B;  3DDQ B;  3X26 B;  1F5Q B;  1VYW B;  3EOC B;  1OL1 B;  4MIM A;  4ELJ A;  3DOG B;  3QYE A;  1XO2 A;  1GH6 B;  2UZL B;  2BS4 A;  2DD4 B;  3QYB A;  1V29 B;  3DJB A;  2DPP B;  2WMA B;  2R7G A;  5L2W B;  2PK9 B;  4EOQ B;  4BCO B;  4NC6 A;  1H4L D;  5HNB B;  3HB9 A;  4UN0 A;  2ZPB B;  4BCJ B;  2CZ0 B;  5CEI B;  2C5N B;  5HBJ B;  2ZZD B;  1D3U B;  1QMZ B;  2C5V B;  4F7N B;  5IDP B;  4M6V A;  1TD6 A;  3EID B;  3K7A M;  3A8L B;  1W98 B;  3PO3 S;  3VKG A;  4CXA B;  4AKH A;  2W2H A;  4HL4 A;  4BCH B;  4BCK B;  1UGP B;  4CFM B;  1UNL D;  2QDY B;  1OKW B;  2D0Q B;  4OB1 B;  2I40 B;  1UGQ B;  4IMY B;  3TN8 B;  1H1S B;  3A8G B;  4OR5 B;  3QWL A;  4BCG B;  2CZ7 B;  4EC8 B;  4EOP B;  1JOW A;  3EJ1 B;  3BG3 A;  2DXB B;  4JX6 A;  5EFQ B;  2G77 A;  2DD5 B;  2EUF A;  4Y72 B;  2CZ6 B;  3DL1 A;  4BCQ B;  1UGS B;  2BKZ B;  5ACB A;  1GUX A;  3VYH B;  4ZGE B;  2KMG A;  4OB3 B;  5HBH B;  4ZGJ B;  5IF1 B;  2W9Z A;  4BCQ D;  4QSH A;  3BHV B;  2QDJ A;  3DTO A;  4EC9 B;  4CFV B;  3MY1 B;  4EOI B;  4KRC B;  3H4C A;  4MFD A;  1H1Q B;  2WIP B;  3HBL A;  3VKH A;  4ELL A;  2PJQ A;  3BHU B;  4EOO B;  5DQV A;  4TTH A;  2W99 A;  4BCI B;  1AHJ B;  4BXX X;  3MIA B;  2CCI B;  2C5X B;  2UZD B;  1N4M A;  4BY1 X;  3QZ9 B;  1E7P A;  4KRD B;  1GUX B;  3NDQ A;  2QFZ A;  1OGU B;  4Z6Y A;  2WMB B;  1G3N C;  1FIN B;  1BU2 A;  1JSU B;  2G9X B;  2BPM B;  2C6T B;  2W96 A;  4BCF B;  4ROE A;  3BLQ B;  3KHI A;  1GY3 B;  1JST B;  1QLB A;  3A8H B;  4CFX B;  4BCM B;  2DXC B;  5CYI B;  3WVE B;  2CJM B;  2C5O B;  4F6S B;  5BNJ B;  4YOS A;  2W9F A;  4ROD A;  5IDN B;  3F5X B;  3QYH B;  2JGZ B;  3HHT B;  2CYZ B;  4EOL B;  5I5Z B;  4AKG A;  3A8O B;  4F70 B;  2I53 A;  5DQW A;  3TNI B;  1OKV B;  1H27 B;  4G6L B;  4CFU B;  1OIU B;  2ZPI B;  2PK2 A;  4HNV A;  3X25 B;  2IW6 B;  2CZ1 B;  5HQ0 B;  1UGR B;  5ICP B;  4YOO A;  4OB2 B;  4BCN B;  4OGR B;  4HNU A;  2WFY B;  2V22 B;  2IW9 B;  4CFU D;  2WEV B;  3QHR B; 
#chains in the Genus database with same CATH homology
 3EID B;  3K7A M;  1W98 B;  2IW8 B;  1PKD B;  1OL2 B;  2B9R A;  2CCI B;  3MIA B;  4BCN D;  1VOL A;  2C5X B;  2UZD B;  1N4M A;  1H24 B;  2IVX A;  3O0G D;  4CXA B;  2UZB B;  3BHT B;  2W2H A;  3BLR B;  4KRD B;  4BCK B;  1GUX B;  2WPA B;  1UNL D;  1ZP2 A;  3DDP B;  4BCH B;  4CFM B;  4EON B;  5LMK B;  2WIH B;  4YOZ A;  1OKW B;  1FVV B;  1O9K A;  4EOR B;  1OGU B;  2I40 B;  1H1R B;  4F7S B;  1JKW A;  3M03 A;  4IMY B;  5LQF B;  1UNH D;  4EOJ B;  3LQ5 B;  3TN8 B;  2WMB B;  5HBE B;  4EOK B;  1H1S B;  1G3N C;  4OR5 B;  4BCP B;  2F2C A;  1FIN B;  1AD6 A;  5HVY B;  3QHR B;  4ROC A;  2C4G B;  1BU2 A;  4BCG B;  1P5E B;  1JSU B;  2G9X B;  1OI9 B;  4EC8 B;  2BPM B;  4EOP B;  2C6T B;  1H28 B;  2W96 A;  5FGK B;  4BCF B;  1JOW A;  3EJ1 B;  3BLQ B;  4ROE A;  4EOS B;  1OIY B;  4CRL B;  1VIN A;  1GY3 B;  1JST B;  4YC3 B;  5EFQ B;  2UUE B;  1KXU A;  3QHW B;  3TNH B;  3MI9 B;  4CFX B;  4BCM B;  5CYI B;  3BLH B;  2EUF A;  4Y72 B;  2X1N B;  4FX3 B;  4BCQ B;  2CJM B;  2PMI B;  3G33 B;  3POM A;  3RGF B;  2C5O B;  1URC B;  2WXV B;  4F6S B;  4CFN B;  1H26 B;  2BKZ B;  5ACB A;  5BNJ B;  4I3Z B;  1GUX A;  4YOS A;  2W9F A;  3TNW B;  3DDQ B;  4ROD A;  5IDN B;  3F5X B;  2PHG A;  2JGZ B;  2WHB B;  5HBH B;  1F5Q B;  5IF1 B;  2W9Z A;  1VYW B;  3EOC B;  4EOL B;  4BCQ D;  1H25 B;  1OL1 B;  1C9B A;  4ELJ A;  3BHV B;  3DOG B;  5I5Z B;  2QDJ A;  4F70 B;  2UZE B;  1O9K B;  2I53 A;  1XO2 A;  1GH6 B;  4EC9 B;  2UZL B;  3TNI B;  1OKV B;  1H27 B;  1H1P B;  1UNG D;  4CFV B;  3MY1 B;  4G6L B;  4CFU B;  1OIU B;  4F7L B;  2PK2 A;  2WMA B;  3MY5 B;  2R7G A;  5L2W B;  4EOI B;  4NST B;  2PK9 B;  4EOQ B;  4KRC B;  4BCO B;  1H4L D;  1TFB A;  5HNB B;  2IW6 B;  4F6W B;  4F7J B;  4UN0 A;  3H4C A;  1H1Q B;  5HQ0 B;  2WIP B;  4BCJ B;  5ICP B;  4YOO A;  4BCM D;  4ELL A;  4BCN B;  4OGR B;  2C5N B;  2WFY B;  5CEI B;  2V22 B;  3BHU B;  5HBJ B;  4EOO B;  2IW9 B;  4CFU D;  1D3U B;  4CFW B;  1QMZ B;  2C5V B;  4F7N B;  2WEV B;  5IDP B;  4TTH A;  1AIS B;  2CCH B;  2W99 A;  4II5 B;  4BCI B;  1E9H B;  4EOM B;  4F6U B;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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