4F7LB

Crystal structure of human cdk8/cycc in complex with compound 2 (tert-butyl [3-({[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]carbamoyl}amino)propyl]carbamate)
Total Genus 85

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
266
structure length
266
Chain Sequence
KAMAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDARQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKMPKPKPPP

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
3H1 (5-7)TI1 (1-4)AH8 (155-166)AH1 (9-14)3H3 (188-190)AH2 (18-30)AH3 (34-55)AH4 (59-75)AH6 (105-120)EMPTYAH5 (83-98)TI2 (77-80)TIV1 (78-81)TVIII1 (79-82)AH7 (132-146)AH9 (172-184)TI3 (168-171)AH12 (224-243)AH10 (194-209)AH13 (246-256)3H2 (121-123)AH11 (214-219)TI'1 (146-149)Updating...
connected with : NaN
molecule tags Transferase/transcription/inhibitor
source organism Homo sapiens
publication title Structure-kinetic relationship study of CDK8/CycC specific compounds.
pubmed doi rcsb
molecule keywords Cyclin-dependent kinase 8
total genus 85
structure length 266
sequence length 266
ec nomenclature
pdb deposition date 2012-05-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00134 Cyclin_N Cyclin, N-terminal domain
B PF16899 Cyclin_C_2 Cyclin C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.472.10 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin-like 4f7lB02
1.10.472.10 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin-like 4f7lB01
3TNWB 4ELLA 4BCFB 4CFWB 5HNBB 4EOKB 5LMKB 1PKDB 1GUXA 2UZEB 1GH6B 5HQ0B 1OKVB 2C5VB 3MY1B 2W99A 4EORB 2CJMB 4NSTB 4F70B 4F6UB 2C4GB 3DDPB 2WEVB 2WIPB 2UZBB 1JOWA 4BCMD 5FGKB 4OGRB 4F7NB 2IW9B 4BCND 4EOJB 1URCB 4CFNB 3O0GD 2I53A 1JSUB 1UNGD 2C5NB 4YC3B 4CXAB 5IDPB 5ICPB 2WFYB 2WXVB 1H24B 4I3ZB 4KRDB 4BCJB 4EOQB 1H25B 4BCNB 3TNHB 1KXUA 1H1RB 3TNIB 4BCPB 2PMIB 1BU2A 1H1QB 3EJ1B 5IDNB 4II5B 1H26B 4YOZA 5CYIB 1GY3B 2IVXA 4EOMB 4Y72B 3POMA 2JGZB 3DDQB 1AD6A 3G33B 2W9ZA 4YOSA 2IW8B 2PK9B 4UN0A 3RGFB 3BHVB 1UNLD 4BCOB 4OR5B 2UZLB 3MY5B 4BCHB 4BCIB 2BKZB 1GUXB 1E9HB 1OGUB 1JSTB 3MI9B 3QHWB 1OKWB 1W98B 3F5XB 4CRLB 5L2WB 4F7JB 1O9KA 2PHGA 3EIDB 1OIYB 2IW6B 1UNHD 2G9XB 3DOGB 4IMYB 4CFXB 4ROEA 3BLQB 1H1PB 4F6SB 1C9BA 1D3UB 2W2HA 2WPAB 2WHBB 4EOOB 2WMBB 2R7GA 2WIHB 2C6TB 5HBHB 2EUFA 4BCQB 5HBEB 3K7AM 4RODA 5IF1B 2CCHB 5EFQB 4ROCA 4TTHA 3BHTB 1FVVB 2X1NB 4F6WB 2UUEB 1OL2B 1FINB 1OL1B 4F7SB 2B9RA 2WMAB 5HBJB 1VYWB 2CCIB 1H28B 4CFMB 2PK2A 1AISB 5LQFB 1H1SB 4EOIB 1XO2A 4EOLB 2UZDB 2W9FA 1ZP2A 3H4CA 3LQ5B 4EOPB 1QMZB 2I40B 4EC8B 4CFUB 1OI9B 4BCQD 4EC9B 5BNJB 1OIUB 5HVYB 1N4MA 1H27B 1P5EB 1G3NC 2C5OB 3EOCB 1F5QB 2W96A 2BPMB 1H4LD 4CFVB 2QDJA 4EOSB 1JKWA 3TN8B 3QHRB 1VOLA 2C5XB 1TFBA 2F2CA 4EONB 2V22B 4F7LB 4BCKB 4G6LB 3M03A 4KRCB 4FX3B 4ELJA 1O9KB 3MIAB 4CFUD 5CEIB 3BHUB 3BLHB 4BCMB 5I5ZB 4YOOA 1VINA 4BCGB 3BLRB 5ACBA
chains in the Genus database with same CATH superfamily
4BCFB 5HNBB 1IREB 1PKDB 5IHYA 5HQ0B 4EORB 4NSTB 3HZJA 2C4GB 4BY1X 4LOCA 1URCB 4CXAB 4BBRM 1H24B 3X28B 1V29B 1H25B 5IDNB 1H26B 5DQWA 3WVEB 5CYIB 1GY3B 2IVXA 3POMA 3X26B 3DDQB 2W9ZA 4YOSA 2DPPB 4UN0A 4MIMA 3HHTB 4OR5B 2UZLB 4BCIB 1E9HB 2CYZB 3QHWB 1OKWB 3F5XB 4CRLB 4CFXB 4IMYB 4ROEA 3BLQB 1H1PB 1C9BA 2W2HA 2QFZA 2PJQA 4MFEA 4EOOB 2R7GA 2WIHB 4BCQB 5HBEB 3QWLA 5IF1B 4TTHA 4HLQA 4F7SB 2B9RA 4CFMB 1H28B 2W9FA 1ZP2A 3H4CA 3LQ5B 4EC8B 3DJBA 1OI9B 2DMEA 5HVYB 1G3NC 3EOCB 3VKHA 2KMGA 1H4LD 2QDJA 1VOLA 1ENWA 2C5XB 2F2CA 2QGSA 4G6LB 2ZPFB 4FX3B 4ELJA 5CEIB 1UGQB 2QF7A 1VINA 4ZGEB 4ELLA 5EJCA 4CFWB 4EOKB 5LMKB 4ZGJB 1GUXA 2ZCFB 1UGSB 2W99A 2CJMB 4OB2B 3DDPB 2WIPB 3NDQA 2UZBB 1JOWA 4OB1B 5DQVA 4CFNB 4HL4A 3BG9A 1JSUB 2WXVB 4I3ZB 4KRDB 1TD6A 3KHIA 4BCNB 3TNHB 3TNIB 1BU2A 1H1QB 3VYHB 4HNVA 4YOZA 4Z6YA 4EOMB 4Y72B 2JGZB 3VKGA 2PK9B 3RGFB 2AHJB 2IN3A 4OB3B 1GUXB 1OGUB 1W98B 5L2WB 2DD5B 4BY7X 3BG3A 2IW6B 3DOGB 2ZPIB 3A8HB 2C6TB 4BBSM 3HBLA 3K7AM 4RODA 1UGRB 2X1NB 4F6WB 1OL2B 2PK2A 1AISB 4EOLB 3A8LB 1QMZB 3QYBA 3HB9A 5BNJB 1N4MA 1H27B 4QSHA 3WVDB 1F5QB 2BPMB 1JKWA 3QZ9B 1TFBA 2V22B 2QQ8A 5I5ZB 4YOOA 3BLRB 2ZPGB 1GH6B 3DL1A 1OKVB 2C5VB 4JX6A 2D0QB 3VYGB 4OB0B 4BCMD 4F7NB 4EOJB 2I53A 1UNGD 2C5NB 4YC3B 5IDPB 2WFYB 4BXXX 1KXUA 1H1RB 2LW4A 4BCPB 3EJ1B 4NC6A 4II5B 2ZPHB 1AD6A 3TW6A 4HNTA 3QZ5B 2CZ6B 2IW8B 3BHVB 2QDYB 1UNLD 2BKZB 4AKGA 1JSTB 3MI9B 2CZ0B 2CZ1B 1O9KA 4M6VA 2PHGA 3A8GB 3EIDB 1OIYB 2ZZDB 2G9XB 3QYHB 2BS4A 2WPAB 2WHBB 2WMBB 2CCHB 3A8MB 3BHTB 2UUEB 1FINB 2WMAB 1VYWB 2CCIB 5LQFB 1H1SB 1XO2A 1FKMA 4EOPB 2ZPEB 3TW7A 3QYEA 2W96A 4JX4A 4CFVB 4EOSB 3TN8B 3QHRB 4F7LB 4BCKB 2CZ7B 4KRCB 1O9KB 3MIAB 4CFUD 3GTMS 3BLHB 4BCMB 4BCGB 5ACBA 3TNWB 2UZEB 4AKHA 3MY1B 4JX5A 4F70B 4F6UB 2DXBB 2WEVB 3X25B 5FGKB 4OGRB 2IW9B 4BCND 3O0GD 3X24B 5ICPB 2WJ9A 4ZGDB 3DTOA 3BG5A 4BCJB 4EOQB 3X20B 3QYGB 2PMIB 3A8OB 3G33B 4MFDA 2DD4B 2DXCB 1AHJB 3HO8A 3MY5B 4BCHB 4F7JB 2KR6A 1QLBA 1UNHD 4F6SB 2BS3A 1D3UB 5HBHB 2EUFA 4AI6A 5EFQB 4ROCA 2ZPBB 1FVVB 2BS2A 2G77A 1OL1B 5HBJB 4AKIA 4EOIB 2UZDB 4HNUA 4CFUB 2I40B 4BCQD 1E7PA 3QXEB 4EC9B 1OIUB 1P5EB 2C5OB 4FM4B 4EONB 3B57A 3M03A 3PO3S 3BHUB 1UGPB 4BCOB
chains in the Genus database with same CATH topology
3TNWB 4ELLA 4BCFB 4CFWB 5HNBB 4EOKB 5LMKB 1PKDB 1GUXA 2UZEB 1GH6B 5HQ0B 1OKVB 2C5VB 3MY1B 2W99A 4EORB 2CJMB 4NSTB 4F70B 4F6UB 2C4GB 3DDPB 2WEVB 2WIPB 2UZBB 1JOWA 4BCMD 5FGKB 4OGRB 4F7NB 2IW9B 4BCND 4EOJB 1URCB 4CFNB 3O0GD 2I53A 1JSUB 1UNGD 2C5NB 4YC3B 4CXAB 5IDPB 5ICPB 2WFYB 2WXVB 1H24B 4I3ZB 4KRDB 4BCJB 4EOQB 1H25B 4BCNB 3TNHB 1KXUA 1H1RB 3TNIB 4BCPB 2PMIB 1BU2A 1H1QB 3EJ1B 5IDNB 4II5B 1H26B 4YOZA 5CYIB 1GY3B 2IVXA 4EOMB 4Y72B 3POMA 2JGZB 3DDQB 1AD6A 3G33B 2W9ZA 4YOSA 2IW8B 2PK9B 4UN0A 3RGFB 3BHVB 1UNLD 4BCOB 4OR5B 2UZLB 3MY5B 4BCHB 4BCIB 2BKZB 1GUXB 1E9HB 1OGUB 1JSTB 3MI9B 3QHWB 1OKWB 1W98B 3F5XB 4CRLB 5L2WB 4F7JB 1O9KA 2PHGA 3EIDB 1OIYB 2IW6B 1UNHD 2G9XB 3DOGB 4IMYB 4CFXB 4ROEA 3BLQB 1H1PB 4F6SB 1C9BA 1D3UB 2W2HA 2WPAB 2WHBB 4EOOB 2WMBB 2R7GA 2WIHB 2C6TB 5HBHB 2EUFA 4BCQB 5HBEB 3K7AM 4RODA 5IF1B 2CCHB 5EFQB 4ROCA 4TTHA 3BHTB 1FVVB 2X1NB 4F6WB 2UUEB 1OL2B 1FINB 1OL1B 4F7SB 2B9RA 2WMAB 5HBJB 1VYWB 2CCIB 1H28B 4CFMB 2PK2A 1AISB 5LQFB 1H1SB 4EOIB 1XO2A 4EOLB 2UZDB 2W9FA 1ZP2A 3H4CA 3LQ5B 4EOPB 1QMZB 2I40B 4EC8B 4CFUB 1OI9B 4BCQD 4EC9B 5BNJB 1OIUB 5HVYB 1N4MA 1H27B 1P5EB 1G3NC 2C5OB 3EOCB 1F5QB 2W96A 2BPMB 1H4LD 4CFVB 2QDJA 4EOSB 1JKWA 3TN8B 3QHRB 1VOLA 2C5XB 1TFBA 2F2CA 4EONB 2V22B 4F7LB 4BCKB 4G6LB 3M03A 4KRCB 4FX3B 4ELJA 1O9KB 3MIAB 4CFUD 5CEIB 3BHUB 3BLHB 4BCMB 5I5ZB 4YOOA 1VINA 4BCGB 3BLRB 5ACBA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3TNW B;  4ELL A;  4BCF B;  4CFW B;  5HNB B;  4EOK B;  5LMK B;  1PKD B;  1GUX A;  2UZE B;  1GH6 B;  5HQ0 B;  1OKV B;  2C5V B;  3MY1 B;  2W99 A;  4EOR B;  2CJM B;  4NST B;  4F70 B;  4F6U B;  2C4G B;  3DDP B;  2WEV B;  2WIP B;  2UZB B;  1JOW A;  4BCM D;  5FGK B;  4OGR B;  4F7N B;  2IW9 B;  4BCN D;  4EOJ B;  1URC B;  4CFN B;  3O0G D;  2I53 A;  1JSU B;  1UNG D;  2C5N B;  4YC3 B;  4CXA B;  5IDP B;  5ICP B;  2WFY B;  2WXV B;  1H24 B;  4I3Z B;  4KRD B;  4BCJ B;  4EOQ B;  1H25 B;  4BCN B;  3TNH B;  1KXU A;  1H1R B;  3TNI B;  4BCP B;  2PMI B;  1BU2 A;  1H1Q B;  3EJ1 B;  5IDN B;  4II5 B;  1H26 B;  4YOZ A;  5CYI B;  1GY3 B;  2IVX A;  4EOM B;  4Y72 B;  3POM A;  2JGZ B;  3DDQ B;  1AD6 A;  3G33 B;  2W9Z A;  4YOS A;  2IW8 B;  2PK9 B;  4UN0 A;  3RGF B;  3BHV B;  1UNL D;  4BCO B;  4OR5 B;  2UZL B;  3MY5 B;  4BCH B;  4BCI B;  2BKZ B;  1GUX B;  1E9H B;  1OGU B;  1JST B;  3MI9 B;  3QHW B;  1OKW B;  1W98 B;  3F5X B;  4CRL B;  5L2W B;  4F7J B;  1O9K A;  2PHG A;  3EID B;  1OIY B;  2IW6 B;  1UNH D;  2G9X B;  3DOG B;  4IMY B;  4CFX B;  4ROE A;  3BLQ B;  1H1P B;  4F6S B;  1C9B A;  1D3U B;  2W2H A;  2WPA B;  2WHB B;  4EOO B;  2WMB B;  2R7G A;  2WIH B;  2C6T B;  5HBH B;  2EUF A;  4BCQ B;  5HBE B;  3K7A M;  4ROD A;  5IF1 B;  2CCH B;  5EFQ B;  4ROC A;  4TTH A;  3BHT B;  1FVV B;  2X1N B;  4F6W B;  2UUE B;  1OL2 B;  1FIN B;  1OL1 B;  4F7S B;  2B9R A;  2WMA B;  5HBJ B;  1VYW B;  2CCI B;  1H28 B;  4CFM B;  2PK2 A;  1AIS B;  5LQF B;  1H1S B;  4EOI B;  1XO2 A;  4EOL B;  2UZD B;  2W9F A;  1ZP2 A;  3H4C A;  3LQ5 B;  4EOP B;  1QMZ B;  2I40 B;  4EC8 B;  4CFU B;  1OI9 B;  4BCQ D;  4EC9 B;  5BNJ B;  1OIU B;  5HVY B;  1N4M A;  1H27 B;  1P5E B;  1G3N C;  2C5O B;  3EOC B;  1F5Q B;  2W96 A;  2BPM B;  1H4L D;  4CFV B;  2QDJ A;  4EOS B;  1JKW A;  3TN8 B;  3QHR B;  1VOL A;  2C5X B;  1TFB A;  2F2C A;  4EON B;  2V22 B;  4F7L B;  4BCK B;  4G6L B;  3M03 A;  4KRC B;  4FX3 B;  4ELJ A;  1O9K B;  3MIA B;  4CFU D;  5CEI B;  3BHU B;  3BLH B;  4BCM B;  5I5Z B;  4YOO A;  1VIN A;  4BCG B;  3BLR B;  5ACB A; 
#chains in the Genus database with same CATH topology
 4BCF B;  5HNB B;  1IRE B;  1PKD B;  5IHY A;  5HQ0 B;  4EOR B;  4NST B;  3HZJ A;  2C4G B;  4BY1 X;  4LOC A;  1URC B;  4CXA B;  4BBR M;  1H24 B;  3X28 B;  1V29 B;  1H25 B;  5IDN B;  1H26 B;  5DQW A;  3WVE B;  5CYI B;  1GY3 B;  2IVX A;  3POM A;  3X26 B;  3DDQ B;  2W9Z A;  4YOS A;  2DPP B;  4UN0 A;  4MIM A;  3HHT B;  4OR5 B;  2UZL B;  4BCI B;  1E9H B;  2CYZ B;  3QHW B;  1OKW B;  3F5X B;  4CRL B;  4CFX B;  4IMY B;  4ROE A;  3BLQ B;  1H1P B;  1C9B A;  2W2H A;  2QFZ A;  2PJQ A;  4MFE A;  4EOO B;  2R7G A;  2WIH B;  4BCQ B;  5HBE B;  3QWL A;  5IF1 B;  4TTH A;  4HLQ A;  4F7S B;  2B9R A;  4CFM B;  1H28 B;  2W9F A;  1ZP2 A;  3H4C A;  3LQ5 B;  4EC8 B;  3DJB A;  1OI9 B;  2DME A;  5HVY B;  1G3N C;  3EOC B;  3VKH A;  2KMG A;  1H4L D;  2QDJ A;  1VOL A;  1ENW A;  2C5X B;  2F2C A;  2QGS A;  4G6L B;  2ZPF B;  4FX3 B;  4ELJ A;  5CEI B;  1UGQ B;  2QF7 A;  1VIN A;  4ZGE B;  4ELL A;  5EJC A;  4CFW B;  4EOK B;  5LMK B;  4ZGJ B;  1GUX A;  2ZCF B;  1UGS B;  2W99 A;  2CJM B;  4OB2 B;  3DDP B;  2WIP B;  3NDQ A;  2UZB B;  1JOW A;  4OB1 B;  5DQV A;  4CFN B;  4HL4 A;  3BG9 A;  1JSU B;  2WXV B;  4I3Z B;  4KRD B;  1TD6 A;  3KHI A;  4BCN B;  3TNH B;  3TNI B;  1BU2 A;  1H1Q B;  3VYH B;  4HNV A;  4YOZ A;  4Z6Y A;  4EOM B;  4Y72 B;  2JGZ B;  3VKG A;  2PK9 B;  3RGF B;  2AHJ B;  2IN3 A;  4OB3 B;  1GUX B;  1OGU B;  1W98 B;  5L2W B;  2DD5 B;  4BY7 X;  3BG3 A;  2IW6 B;  3DOG B;  2ZPI B;  3A8H B;  2C6T B;  4BBS M;  3HBL A;  3K7A M;  4ROD A;  1UGR B;  2X1N B;  4F6W B;  1OL2 B;  2PK2 A;  1AIS B;  4EOL B;  3A8L B;  1QMZ B;  3QYB A;  3HB9 A;  5BNJ B;  1N4M A;  1H27 B;  4QSH A;  3WVD B;  1F5Q B;  2BPM B;  1JKW A;  3QZ9 B;  1TFB A;  2V22 B;  2QQ8 A;  5I5Z B;  4YOO A;  3BLR B;  2ZPG B;  1GH6 B;  3DL1 A;  1OKV B;  2C5V B;  4JX6 A;  2D0Q B;  3VYG B;  4OB0 B;  4BCM D;  4F7N B;  4EOJ B;  2I53 A;  1UNG D;  2C5N B;  4YC3 B;  5IDP B;  2WFY B;  4BXX X;  1KXU A;  1H1R B;  2LW4 A;  4BCP B;  3EJ1 B;  4NC6 A;  4II5 B;  2ZPH B;  1AD6 A;  3TW6 A;  4HNT A;  3QZ5 B;  2CZ6 B;  2IW8 B;  3BHV B;  2QDY B;  1UNL D;  2BKZ B;  4AKG A;  1JST B;  3MI9 B;  2CZ0 B;  2CZ1 B;  1O9K A;  4M6V A;  2PHG A;  3A8G B;  3EID B;  1OIY B;  2ZZD B;  2G9X B;  3QYH B;  2BS4 A;  2WPA B;  2WHB B;  2WMB B;  2CCH B;  3A8M B;  3BHT B;  2UUE B;  1FIN B;  2WMA B;  1VYW B;  2CCI B;  5LQF B;  1H1S B;  1XO2 A;  1FKM A;  4EOP B;  2ZPE B;  3TW7 A;  3QYE A;  2W96 A;  4JX4 A;  4CFV B;  4EOS B;  3TN8 B;  3QHR B;  4F7L B;  4BCK B;  2CZ7 B;  4KRC B;  1O9K B;  3MIA B;  4CFU D;  3GTM S;  3BLH B;  4BCM B;  4BCG B;  5ACB A;  3TNW B;  2UZE B;  4AKH A;  3MY1 B;  4JX5 A;  4F70 B;  4F6U B;  2DXB B;  2WEV B;  3X25 B;  5FGK B;  4OGR B;  2IW9 B;  4BCN D;  3O0G D;  3X24 B;  5ICP B;  2WJ9 A;  4ZGD B;  3DTO A;  3BG5 A;  4BCJ B;  4EOQ B;  3X20 B;  3QYG B;  2PMI B;  3A8O B;  3G33 B;  4MFD A;  2DD4 B;  2DXC B;  1AHJ B;  3HO8 A;  3MY5 B;  4BCH B;  4F7J B;  2KR6 A;  1QLB A;  1UNH D;  4F6S B;  2BS3 A;  1D3U B;  5HBH B;  2EUF A;  4AI6 A;  5EFQ B;  4ROC A;  2ZPB B;  1FVV B;  2BS2 A;  2G77 A;  1OL1 B;  5HBJ B;  4AKI A;  4EOI B;  2UZD B;  4HNU A;  4CFU B;  2I40 B;  4BCQ D;  1E7P A;  3QXE B;  4EC9 B;  1OIU B;  1P5E B;  2C5O B;  4FM4 B;  4EON B;  3B57 A;  3M03 A;  3PO3 S;  3BHU B;  1UGP B;  4BCO B; 
#chains in the Genus database with same CATH homology
 3TNW B;  4ELL A;  4BCF B;  4CFW B;  5HNB B;  4EOK B;  5LMK B;  1PKD B;  1GUX A;  2UZE B;  1GH6 B;  5HQ0 B;  1OKV B;  2C5V B;  3MY1 B;  2W99 A;  4EOR B;  2CJM B;  4NST B;  4F70 B;  4F6U B;  2C4G B;  3DDP B;  2WEV B;  2WIP B;  2UZB B;  1JOW A;  4BCM D;  5FGK B;  4OGR B;  4F7N B;  2IW9 B;  4BCN D;  4EOJ B;  1URC B;  4CFN B;  3O0G D;  2I53 A;  1JSU B;  1UNG D;  2C5N B;  4YC3 B;  4CXA B;  5IDP B;  5ICP B;  2WFY B;  2WXV B;  1H24 B;  4I3Z B;  4KRD B;  4BCJ B;  4EOQ B;  1H25 B;  4BCN B;  3TNH B;  1KXU A;  1H1R B;  3TNI B;  4BCP B;  2PMI B;  1BU2 A;  1H1Q B;  3EJ1 B;  5IDN B;  4II5 B;  1H26 B;  4YOZ A;  5CYI B;  1GY3 B;  2IVX A;  4EOM B;  4Y72 B;  3POM A;  2JGZ B;  3DDQ B;  1AD6 A;  3G33 B;  2W9Z A;  4YOS A;  2IW8 B;  2PK9 B;  4UN0 A;  3RGF B;  3BHV B;  1UNL D;  4BCO B;  4OR5 B;  2UZL B;  3MY5 B;  4BCH B;  4BCI B;  2BKZ B;  1GUX B;  1E9H B;  1OGU B;  1JST B;  3MI9 B;  3QHW B;  1OKW B;  1W98 B;  3F5X B;  4CRL B;  5L2W B;  4F7J B;  1O9K A;  2PHG A;  3EID B;  1OIY B;  2IW6 B;  1UNH D;  2G9X B;  3DOG B;  4IMY B;  4CFX B;  4ROE A;  3BLQ B;  1H1P B;  4F6S B;  1C9B A;  1D3U B;  2W2H A;  2WPA B;  2WHB B;  4EOO B;  2WMB B;  2R7G A;  2WIH B;  2C6T B;  5HBH B;  2EUF A;  4BCQ B;  5HBE B;  3K7A M;  4ROD A;  5IF1 B;  2CCH B;  5EFQ B;  4ROC A;  4TTH A;  3BHT B;  1FVV B;  2X1N B;  4F6W B;  2UUE B;  1OL2 B;  1FIN B;  1OL1 B;  4F7S B;  2B9R A;  2WMA B;  5HBJ B;  1VYW B;  2CCI B;  1H28 B;  4CFM B;  2PK2 A;  1AIS B;  5LQF B;  1H1S B;  4EOI B;  1XO2 A;  4EOL B;  2UZD B;  2W9F A;  1ZP2 A;  3H4C A;  3LQ5 B;  4EOP B;  1QMZ B;  2I40 B;  4EC8 B;  4CFU B;  1OI9 B;  4BCQ D;  4EC9 B;  5BNJ B;  1OIU B;  5HVY B;  1N4M A;  1H27 B;  1P5E B;  1G3N C;  2C5O B;  3EOC B;  1F5Q B;  2W96 A;  2BPM B;  1H4L D;  4CFV B;  2QDJ A;  4EOS B;  1JKW A;  3TN8 B;  3QHR B;  1VOL A;  2C5X B;  1TFB A;  2F2C A;  4EON B;  2V22 B;  4F7L B;  4BCK B;  4G6L B;  3M03 A;  4KRC B;  4FX3 B;  4ELJ A;  1O9K B;  3MIA B;  4CFU D;  5CEI B;  3BHU B;  3BLH B;  4BCM B;  5I5Z B;  4YOO A;  1VIN A;  4BCG B;  3BLR B;  5ACB A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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