4KM5A

X-ray crystal structure of human cyclic gmp-amp synthase (cgas)
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
362
structure length
362
Chain Sequence
GASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNTGSYYEHVKISAPNEFDVMFKLEVPRIQLEEYSNTRAYYFVKFKRNPKENPLSQFLEGEILSASKMLSKFRKIIKEEINDIKDTDVIMKRKRGGSPAVTLLISEKISVDITLALESKSSWPASTQEGLRIQNWLSAKVRKQLRLKPFYLVPKHAKEGNGFQEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCRKDCLKLMKYLLEQLKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWDRKDLGLCFDNCVTYFLQCLRTEKLENYFIPEFNLFSSNLIDKRSKEFLTKQIEYERNNEFPVFDEF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Cyclic GMP-AMP synthase
publication title Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 105
structure length 362
sequence length 362
ec nomenclature ec 2.7.7.86: Cyclic GMP-AMP synthase.
pdb deposition date 2013-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03281 Mab-21 Mab-21 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1410.40 Mainly Alpha Orthogonal Bundle Poly(a)-polymerase, middle domain Poly(a)-polymerase, middle domain 4km5A01
3.30.460.90 Alpha Beta 2-Layer Sandwich Beta Polymerase; domain 2 Beta Polymerase; domain 2 4km5A02
4LEWA 4OAFA 4K9AA 4AT8B 4K96A 4AT9A 4O6AA 4LEZA 4O67A 4NXXA 4AT7A 4K98A 4AT9B 4O69A 4MKPA 4AT7B 4JLZA 4NXWA 4OAGA 4K8VA 4WOYA 4ATBA 4LEYA 4OAHA 4K97A 4KM5A 4O68A 4ATBB 4JLXA 4KB6A 4K9BA 4LEVA 4AT8A 4OAIZ 4NXVA 4K99A 4NXTA 4NXUA
chains in the Genus database with same CATH superfamily
4X4RA 1ZQCA 3UQ2A 3V7KA 5DB9A 9ICNA 8ICAA 8ICHA 2EWRA 1UEUA 4F5OA 4WC5A 4I2EA 8ICBA 4LT6A 3B0XA 1ZQNA 4NLNA 8ICFA 4UB5A 1BPEA 4IQVA 4FO6A 9ICGA 4LZGA 5J2DA 2ZH8A 3JPQA 7ICRA 1JQRA 9ICSA 5F2VO 4E8FA 4WCWA 4F5RA 4JWMA 1ZQDA 5CFUA 8ICVA 4K4GA 5HRHA 5DEDA 3LQCB 3RJGA 4EEBA 5D62A 4I2BA 4K99A 5J0WA 2GAFD 1OU5A 5J29A 4YD1A 4K9AA 3UPQA 3ER8C 7ICSA 5HHHA 4O9MA 2M2UA 2BPGA 3MDAA 4I2GA 4RT3A 4KLHA 2HHPA 4EP7A 5DBBA 4XRHA 4X4QA 1PX5A 4HX0A 9ICVA 5CFSA 2W9MA 3JPSA 1ZQTA 4X4UA 3H38A 4E80A 4Z6DA 4R65A 4I2AA 3JPRA 4RWPA 4DO9A 4QZ9A 5J2CA 2BCVA 2ZH7A 3V7LA 7ICJA 2NRKA 4OAIZ 7ICNA 1ZQGA 3RJKA 3C5GA 4I29A 5HRFA 4F5NA 4AT7A 4XQ7A 4RT2A 3PMLA 1YLQA 1JMSA 4I2CA 5EOZA 5DBCA 5J0QA 3H3AA 3WFRE 5CB1A 4M9LA 3UXPA 7ICMA 5HC9A 2ZH9A 4DOAA 2IUBA 4QZHA 4ATBB 8ICCA 5DB6A 4P4PA 4F5PA 5IINA 3GDXA 1MIWA 4NXVA 2ID1A 8ICXA 8ICUA 1BPBA 5DBAA 1ZJNA 2DR5A 5CJ7A 4KLEA 8ICOA 5DB7A 1HUZA 4FHYA 4QZEA 3AU2A 4EBKA 8ICMA 5B3QA 2HN1A 4UB2A 2IHOA 3JYYA 8ICKA 1ZQQA 2FMPA 4KB6A 3HW8A 1Q79A 1HUOA 4WQLA 1JAJA 4GXIA 5J0OA 4UB4A 2B56A 2ZH4A 1ZQBA 4M9JA 9ICRA 4PGYA 1TV9A 1F5AA 4WC1A 1ZQUA 1ZJMA 4K98A 3OWGA 5HRLA 5J2GA 2BCQA 4KLMA 4RQ4A 4O69A 4MKPA 4QZAA 5J0XA 3K75D 3RH4A 1VFGA 4O5EA 4YN4A 2BBHA 5J2JA 4NXWA 5DKWA 3NWIA 4UB3A 1TVAA 9ICPA 5J0TA 3JPPA 8ICRA 7ICTA 4Z6FA 4M2YA 1ZQFA 3OGUA 3RH6A 2PBEA 5HRKA 5J2FA 4JWNA 4R66A 3WFPA 3HWTA 4AT8B 4S3NA 4X4TA 4YMOA 4YD2A 3MGHA 2BCRA 2ZH6A 2BCSA 3NKUA 4RPYA 5B3PA 3NYBA 4WBYA 4EEDA 1UEVA 5HRBA 3TFSA 9ICLA 1ZQMA 3OVAA 4TUSA 4KLIA 4TUPA 5HHIA 2DR8A 5CFTA 4AT8A 4FHPA 1V4AA 1XSLA 5IIKA 4NLKA 3B0YA 4WH5A 9ICBA 4PHAA 4EV6A 4K4IA 1ZQPA 2ZH5A 3C5FA 4QZCA 2PFNA 4LVSA 4XUSA 1MQ3A 1BPDA 1MIYA 3ISDA 3WFSC 4I0UA 4PGXA 7ICPA 4LEYA 1MIVA 4N7RA 4PHDA 5CR0A 4M9HA 4FHXA 4I2DA 4F5QA 4FHVA 4R64A 1BPYA 3JZ0A 4RQ8A 9ICFA 4LEZA 4X4NA 4NKTA 4X0AA 4LZDA 2GWSA 4QZ8A 4UAYA 8ICPA 7ICHA 1WOTA 7ICEA 4EBJA 4PH5A 4UAZA 4K8VA 5BPCA 4RWNA 1R8AA 4I2JA 5IILA 2DVIA 3AQNA 2M2TA 1ZQZA 3RH5A 8ICTA 5J2AA 4RQ1A 4I2IA 4TURA 5DECA 4NXUA 3C2KA 5BOMA 2M2VA 3OUYB 3C18A 4WC0A 5J2BA 4WC7A 5IIMA 3HJ4A 4NY8A 3ER9B 3K7DA 1ZQLA 3LK9A 8ICLA 3RJJA 4JLZA 4IQUA 4I2HA 2O1PA 4RWQA 4QZDA 3UXNA 4EGWA 4ATBA 7ICQA 4K97A 4TUQA 4KM5A 1BPZA 1BPXA 5HREA 4M9NA 1Q78A 3NVOA 4Z6EA 4YCXA 8ICSA 3UXOA 3V7JA 9ICQA 4WC3A 4FH3A 4RQ3A 4UBBA 8ICQA 1KDHA 2PXIA 1ZQVA 4QZFA 4PPXA 3AQLA 4P2HA 3ERCC 4NKUA 4I28A 5J2IA 8ICIA 8ICJA 5D61A 4PGQA 3RJFA 4PHPA 4KLLA 3UPSA 4XJEA 5J0RA 3H39A 3PNCA 1ZQKA 5J0YA 4OAHA 4QZBA 3RJIA 4WBZA 4IQTA 4M9GA 5JTGA 5HRDA 1KEJA 9ICEA 2B51A 2BE3A 3AQMA 4FHWA 1ZQJA 2ISPA 4RQ7A 4KLJA 9ICJA 3HX0A 5J0PA 4UAWA 1MQ2A 3C66A 5CWRA 2PFPA 9ICHA 4OAGA 4XQ8A 1KNYA 4GXJA 4KLDA 5J2HA 3AQKA 7ICIA 4O68A 3RJEA 4FH5A 4JLXA 1JN3A 2BBJA 7ICGA 1R89A 9ICCA 1ZQSA 7ICFA 4I2FA 2PFQA 1ZQEA 4K96A 2ISOA 4MFFA 4KLQA 4NXXA 4XA5A 3ISBA 4AT9B 5IIIA 1ZQXA 2ZH1A 4RQ5A 5CHGA 3AU6A 9ICIA 4YMMA 5D4BA 4WOYA 2FCLA 4RQ2A 1VJ7A 4MFCA 1ZQIA 4X4VA 4YMNA 4FO1A 3V72A 4PHEA 5DDYA 7ICKA 2M2WA 5J0UA 4M0AA 1FA0A 5BOLA 3JPNA 3MDCA 2VANA 4LEWA 9ICOA 4NM2A 3UQ0A 4AT9A 5CHEA 2BPFA 3H37A 4I27A 3MCRA 2Q66A 4WC4A 4UB1A 4K4HA 4M5DA 1NO5A 2DR7A 4AT7B 4X0BA 2PFOA 3JPOA 4RQ0A 3WFQE 4X4PA 4KLTA 3RJHA 4O5KA 3OVBA 1NOMA 2BPCA 1TFYA 4UD5A 9ICKA 4M04A 1R8BA 4X4SA 4Z6CA 5HRGA 2ZHAA 4R63A 4NXZA 5TZVA 3EF2A 3L9DA 4E7XA 5IIOA 4QZIA 4X5VA 5CA7A 3MBYA 2B4VA 5D46A 4O6AA 4NLZA 4RWOA 4RPZA 1ZQYA 4IQWA 4WC6A 2BCUA 2P66A 5J2EA 4RPXA 2I9GA 4KLGA 1TFWA 4KLUA 4P4MA 4RQ6A 4MFAA 3MGIA 3HJ1A 2RFFA 5HRIA 5DB8A 9ICMA 4DOBA 1ZQAA 3OUYA 4OAFA 7ICUA 4KLOA 3WFOA 5J0SA 9ICXA 8ICYA 3TFRA 4NM1A 4P4OA 4IG8A 2FMSA 3PMNA 5DDMA 3AUOA 4MF8A 1ZQRA 2DRBA 2ZH3A 3HIYA 9ICTA 1RPLA 8ICNA 5HR9A 8ICZA 2GA9D 4M47A 3JPTA 2FMQA 2HN2A 4MF2A 2DR9A 1ZQHA 9ICAA 1UETA 2DRAA 4NXTA 1ZQWA 8ICEA 4DOCA 4GXKA 5D63A 7ICVA 5CP2A 4O67A 3OV7A 1RZTA 4O5CA 4KLFA 2O5AA 8ICWA 4UD4A 1R8CA 3JCFA 4KLSA 3C2MA 4X4OA 1XSPA 1ZQOA 4WC2A 2IHMA 1GPJA 9ICWA 5J2KA 5D49A 1XSNA 7ICOA 3PHZA 3OVSA 7ICLA 8ICGA 2ZHBA 5IIJA 3ISCA 4K9BA 3CK6A 3C2LA 4WQKA 2ZH2A 4UBCA 4LEVA 4QZGA 9ICUA
chains in the Genus database with same CATH topology
4X4RA 4LEWA 1F5AA 4AT9A 5CHEA 3OUYB 2EWRA 1UEUA 3MCRA 2Q66A 4K98A 3OWGA 3HJ4A 4M5DA 4O69A 2DR7A 4LT6A 4MKPA 4AT7B 3K7DA 3ER9B 4X4PA 4JLZA 4NXWA 3OVBA 2ZH8A 2O1PA 4UD5A 1TFYA 4ATBA 4E8FA 1R8BA 4X4SA 4K97A 4KM5A 5CFUA 2ZHAA 3EF2A 5D62A 1Q78A 4E7XA 4K99A 2GAFD 4K9AA 4FH3A 4AT8B 2B4VA 4X4TA 3ER8C 4O6AA 3ERCC 4NKUA 2HHPA 4EP7A 2ZH6A 4X4QA 3NKUA 4HX0A 5D61A 5CFSA 5B3PA 3NYBA 4X4UA 4XJEA 1UEVA 4E80A 3OVAA 4OAHA 1TFWA 2DR8A 2ZH7A 3HJ1A 5CFTA 4AT8A 4FHPA 4OAIZ 4WH5A 3OUYA 2B51A 4OAFA 4FHWA 2ZH5A 4AT7A 3C66A 2DRBA 2ZH3A 3HIYA 4OAGA 2ZH9A 2GA9D 4LEYA 4N7RA 4O68A 2DR9A 4FH5A 4JLXA 4ATBB 4FHXA 1R89A 4NXVA 1UETA 2DRAA 4NXTA 4FHVA 5D63A 4K96A 4LEZA 4X4NA 4O67A 4NXXA 3OV7A 2DR5A 4NKTA 4UD4A 1R8CA 4AT9B 4FHYA 4X4OA 2ZH1A 1GPJA 5B3QA 4K8VA 4WOYA 2FCLA 1R8AA 3PHZA 3OVSA 2IHOA 2ZHBA 4X4VA 4FO1A 2DVIA 4KB6A 4K9BA 4WQKA 2ZH2A 1Q79A 4WQLA 4LEVA 2B56A 1FA0A 2ZH4A 4NXUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LEW A;  4OAF A;  4K9A A;  4AT8 B;  4K96 A;  4AT9 A;  4O6A A;  4LEZ A;  4O67 A;  4NXX A;  4AT7 A;  4K98 A;  4AT9 B;  4O69 A;  4MKP A;  4AT7 B;  4JLZ A;  4NXW A;  4OAG A;  4K8V A;  4WOY A;  4ATB A;  4LEY A;  4OAH A;  4K97 A;  4KM5 A;  4O68 A;  4ATB B;  4JLX A;  4KB6 A;  4K9B A;  4LEV A;  4AT8 A;  4OAI Z;  4NXV A;  4K99 A;  4NXT A;  4NXU A; 
#chains in the Genus database with same CATH topology
 4X4R A;  1ZQC A;  3UQ2 A;  3V7K A;  5DB9 A;  9ICN A;  8ICA A;  8ICH A;  2EWR A;  1UEU A;  4F5O A;  4WC5 A;  4I2E A;  8ICB A;  4LT6 A;  3B0X A;  1ZQN A;  4NLN A;  8ICF A;  4UB5 A;  1BPE A;  4IQV A;  4FO6 A;  9ICG A;  4LZG A;  5J2D A;  2ZH8 A;  3JPQ A;  7ICR A;  1JQR A;  9ICS A;  5F2V O;  4E8F A;  4WCW A;  4F5R A;  4JWM A;  1ZQD A;  5CFU A;  8ICV A;  4K4G A;  5HRH A;  5DED A;  3LQC B;  3RJG A;  4EEB A;  5D62 A;  4I2B A;  4K99 A;  5J0W A;  2GAF D;  1OU5 A;  5J29 A;  4YD1 A;  4K9A A;  3UPQ A;  3ER8 C;  7ICS A;  5HHH A;  4O9M A;  2M2U A;  2BPG A;  3MDA A;  4I2G A;  4RT3 A;  4KLH A;  2HHP A;  4EP7 A;  5DBB A;  4XRH A;  4X4Q A;  1PX5 A;  4HX0 A;  9ICV A;  5CFS A;  2W9M A;  3JPS A;  1ZQT A;  4X4U A;  3H38 A;  4E80 A;  4Z6D A;  4R65 A;  4I2A A;  3JPR A;  4RWP A;  4DO9 A;  4QZ9 A;  5J2C A;  2BCV A;  2ZH7 A;  3V7L A;  7ICJ A;  2NRK A;  4OAI Z;  7ICN A;  1ZQG A;  3RJK A;  3C5G A;  4I29 A;  5HRF A;  4F5N A;  4AT7 A;  4XQ7 A;  4RT2 A;  3PML A;  1YLQ A;  1JMS A;  4I2C A;  5EOZ A;  5DBC A;  5J0Q A;  3H3A A;  3WFR E;  5CB1 A;  4M9L A;  3UXP A;  7ICM A;  5HC9 A;  2ZH9 A;  4DOA A;  2IUB A;  4QZH A;  4ATB B;  8ICC A;  5DB6 A;  4P4P A;  4F5P A;  5IIN A;  3GDX A;  1MIW A;  4NXV A;  2ID1 A;  8ICX A;  8ICU A;  1BPB A;  5DBA A;  1ZJN A;  2DR5 A;  5CJ7 A;  4KLE A;  8ICO A;  5DB7 A;  1HUZ A;  4FHY A;  4QZE A;  3AU2 A;  4EBK A;  8ICM A;  5B3Q A;  2HN1 A;  4UB2 A;  2IHO A;  3JYY A;  8ICK A;  1ZQQ A;  2FMP A;  4KB6 A;  3HW8 A;  1Q79 A;  1HUO A;  4WQL A;  1JAJ A;  4GXI A;  5J0O A;  4UB4 A;  2B56 A;  2ZH4 A;  1ZQB A;  4M9J A;  9ICR A;  4PGY A;  1TV9 A;  1F5A A;  4WC1 A;  1ZQU A;  1ZJM A;  4K98 A;  3OWG A;  5HRL A;  5J2G A;  2BCQ A;  4KLM A;  4RQ4 A;  4O69 A;  4MKP A;  4QZA A;  5J0X A;  3K75 D;  3RH4 A;  1VFG A;  4O5E A;  4YN4 A;  2BBH A;  5J2J A;  4NXW A;  5DKW A;  3NWI A;  4UB3 A;  1TVA A;  9ICP A;  5J0T A;  3JPP A;  8ICR A;  7ICT A;  4Z6F A;  4M2Y A;  1ZQF A;  3OGU A;  3RH6 A;  2PBE A;  5HRK A;  5J2F A;  4JWN A;  4R66 A;  3WFP A;  3HWT A;  4AT8 B;  4S3N A;  4X4T A;  4YMO A;  4YD2 A;  3MGH A;  2BCR A;  2ZH6 A;  2BCS A;  3NKU A;  4RPY A;  5B3P A;  3NYB A;  4WBY A;  4EED A;  1UEV A;  5HRB A;  3TFS A;  9ICL A;  1ZQM A;  3OVA A;  4TUS A;  4KLI A;  4TUP A;  5HHI A;  2DR8 A;  5CFT A;  4AT8 A;  4FHP A;  1V4A A;  1XSL A;  5IIK A;  4NLK A;  3B0Y A;  4WH5 A;  9ICB A;  4PHA A;  4EV6 A;  4K4I A;  1ZQP A;  2ZH5 A;  3C5F A;  4QZC A;  2PFN A;  4LVS A;  4XUS A;  1MQ3 A;  1BPD A;  1MIY A;  3ISD A;  3WFS C;  4I0U A;  4PGX A;  7ICP A;  4LEY A;  1MIV A;  4N7R A;  4PHD A;  5CR0 A;  4M9H A;  4FHX A;  4I2D A;  4F5Q A;  4FHV A;  4R64 A;  1BPY A;  3JZ0 A;  4RQ8 A;  9ICF A;  4LEZ A;  4X4N A;  4NKT A;  4X0A A;  4LZD A;  2GWS A;  4QZ8 A;  4UAY A;  8ICP A;  7ICH A;  1WOT A;  7ICE A;  4EBJ A;  4PH5 A;  4UAZ A;  4K8V A;  5BPC A;  4RWN A;  1R8A A;  4I2J A;  5IIL A;  2DVI A;  3AQN A;  2M2T A;  1ZQZ A;  3RH5 A;  8ICT A;  5J2A A;  4RQ1 A;  4I2I A;  4TUR A;  5DEC A;  4NXU A;  3C2K A;  5BOM A;  2M2V A;  3OUY B;  3C18 A;  4WC0 A;  5J2B A;  4WC7 A;  5IIM A;  3HJ4 A;  4NY8 A;  3ER9 B;  3K7D A;  1ZQL A;  3LK9 A;  8ICL A;  3RJJ A;  4JLZ A;  4IQU A;  4I2H A;  2O1P A;  4RWQ A;  4QZD A;  3UXN A;  4EGW A;  4ATB A;  7ICQ A;  4K97 A;  4TUQ A;  4KM5 A;  1BPZ A;  1BPX A;  5HRE A;  4M9N A;  1Q78 A;  3NVO A;  4Z6E A;  4YCX A;  8ICS A;  3UXO A;  3V7J A;  9ICQ A;  4WC3 A;  4FH3 A;  4RQ3 A;  4UBB A;  8ICQ A;  1KDH A;  2PXI A;  1ZQV A;  4QZF A;  4PPX A;  3AQL A;  4P2H A;  3ERC C;  4NKU A;  4I28 A;  5J2I A;  8ICI A;  8ICJ A;  5D61 A;  4PGQ A;  3RJF A;  4PHP A;  4KLL A;  3UPS A;  4XJE A;  5J0R A;  3H39 A;  3PNC A;  1ZQK A;  5J0Y A;  4OAH A;  4QZB A;  3RJI A;  4WBZ A;  4IQT A;  4M9G A;  5JTG A;  5HRD A;  1KEJ A;  9ICE A;  2B51 A;  2BE3 A;  3AQM A;  4FHW A;  1ZQJ A;  2ISP A;  4RQ7 A;  4KLJ A;  9ICJ A;  3HX0 A;  5J0P A;  4UAW A;  1MQ2 A;  3C66 A;  5CWR A;  2PFP A;  9ICH A;  4OAG A;  4XQ8 A;  1KNY A;  4GXJ A;  4KLD A;  5J2H A;  3AQK A;  7ICI A;  4O68 A;  3RJE A;  4FH5 A;  4JLX A;  1JN3 A;  2BBJ A;  7ICG A;  1R89 A;  9ICC A;  1ZQS A;  7ICF A;  4I2F A;  2PFQ A;  1ZQE A;  4K96 A;  2ISO A;  4MFF A;  4KLQ A;  4NXX A;  4XA5 A;  3ISB A;  4AT9 B;  5III A;  1ZQX A;  2ZH1 A;  4RQ5 A;  5CHG A;  3AU6 A;  9ICI A;  4YMM A;  5D4B A;  4WOY A;  2FCL A;  4RQ2 A;  1VJ7 A;  4MFC A;  1ZQI A;  4X4V A;  4YMN A;  4FO1 A;  3V72 A;  4PHE A;  5DDY A;  7ICK A;  2M2W A;  5J0U A;  4M0A A;  1FA0 A;  5BOL A;  3JPN A;  3MDC A;  2VAN A;  4LEW A;  9ICO A;  4NM2 A;  3UQ0 A;  4AT9 A;  5CHE A;  2BPF A;  3H37 A;  4I27 A;  3MCR A;  2Q66 A;  4WC4 A;  4UB1 A;  4K4H A;  4M5D A;  1NO5 A;  2DR7 A;  4AT7 B;  4X0B A;  2PFO A;  3JPO A;  4RQ0 A;  3WFQ E;  4X4P A;  4KLT A;  3RJH A;  4O5K A;  3OVB A;  1NOM A;  2BPC A;  1TFY A;  4UD5 A;  9ICK A;  4M04 A;  1R8B A;  4X4S A;  4Z6C A;  5HRG A;  2ZHA A;  4R63 A;  4NXZ A;  5TZV A;  3EF2 A;  3L9D A;  4E7X A;  5IIO A;  4QZI A;  4X5V A;  5CA7 A;  3MBY A;  2B4V A;  5D46 A;  4O6A A;  4NLZ A;  4RWO A;  4RPZ A;  1ZQY A;  4IQW A;  4WC6 A;  2BCU A;  2P66 A;  5J2E A;  4RPX A;  2I9G A;  4KLG A;  1TFW A;  4KLU A;  4P4M A;  4RQ6 A;  4MFA A;  3MGI A;  3HJ1 A;  2RFF A;  5HRI A;  5DB8 A;  9ICM A;  4DOB A;  1ZQA A;  3OUY A;  4OAF A;  7ICU A;  4KLO A;  3WFO A;  5J0S A;  9ICX A;  8ICY A;  3TFR A;  4NM1 A;  4P4O A;  4IG8 A;  2FMS A;  3PMN A;  5DDM A;  3AUO A;  4MF8 A;  1ZQR A;  2DRB A;  2ZH3 A;  3HIY A;  9ICT A;  1RPL A;  8ICN A;  5HR9 A;  8ICZ A;  2GA9 D;  4M47 A;  3JPT A;  2FMQ A;  2HN2 A;  4MF2 A;  2DR9 A;  1ZQH A;  9ICA A;  1UET A;  2DRA A;  4NXT A;  1ZQW A;  8ICE A;  4DOC A;  4GXK A;  5D63 A;  7ICV A;  5CP2 A;  4O67 A;  3OV7 A;  1RZT A;  4O5C A;  4KLF A;  2O5A A;  8ICW A;  4UD4 A;  1R8C A;  3JCF A;  4KLS A;  3C2M A;  4X4O A;  1XSP A;  1ZQO A;  4WC2 A;  2IHM A;  1GPJ A;  9ICW A;  5J2K A;  5D49 A;  1XSN A;  7ICO A;  3PHZ A;  3OVS A;  7ICL A;  8ICG A;  2ZHB A;  5IIJ A;  3ISC A;  4K9B A;  3CK6 A;  3C2L A;  4WQK A;  2ZH2 A;  4UBC A;  4LEV A;  4QZG A;  9ICU A; 
#chains in the Genus database with same CATH homology
 4X4R A;  4LEW A;  1F5A A;  4AT9 A;  5CHE A;  3OUY B;  2EWR A;  1UEU A;  3MCR A;  2Q66 A;  4K98 A;  3OWG A;  3HJ4 A;  4M5D A;  4O69 A;  2DR7 A;  4LT6 A;  4MKP A;  4AT7 B;  3K7D A;  3ER9 B;  4X4P A;  4JLZ A;  4NXW A;  3OVB A;  2ZH8 A;  2O1P A;  4UD5 A;  1TFY A;  4ATB A;  4E8F A;  1R8B A;  4X4S A;  4K97 A;  4KM5 A;  5CFU A;  2ZHA A;  3EF2 A;  5D62 A;  1Q78 A;  4E7X A;  4K99 A;  2GAF D;  4K9A A;  4FH3 A;  4AT8 B;  2B4V A;  4X4T A;  3ER8 C;  4O6A A;  3ERC C;  4NKU A;  2HHP A;  4EP7 A;  2ZH6 A;  4X4Q A;  3NKU A;  4HX0 A;  5D61 A;  5CFS A;  5B3P A;  3NYB A;  4X4U A;  4XJE A;  1UEV A;  4E80 A;  3OVA A;  4OAH A;  1TFW A;  2DR8 A;  2ZH7 A;  3HJ1 A;  5CFT A;  4AT8 A;  4FHP A;  4OAI Z;  4WH5 A;  3OUY A;  2B51 A;  4OAF A;  4FHW A;  2ZH5 A;  4AT7 A;  3C66 A;  2DRB A;  2ZH3 A;  3HIY A;  4OAG A;  2ZH9 A;  2GA9 D;  4LEY A;  4N7R A;  4O68 A;  2DR9 A;  4FH5 A;  4JLX A;  4ATB B;  4FHX A;  1R89 A;  4NXV A;  1UET A;  2DRA A;  4NXT A;  4FHV A;  5D63 A;  4K96 A;  4LEZ A;  4X4N A;  4O67 A;  4NXX A;  3OV7 A;  2DR5 A;  4NKT A;  4UD4 A;  1R8C A;  4AT9 B;  4FHY A;  4X4O A;  2ZH1 A;  1GPJ A;  5B3Q A;  4K8V A;  4WOY A;  2FCL A;  1R8A A;  3PHZ A;  3OVS A;  2IHO A;  2ZHB A;  4X4V A;  4FO1 A;  2DVI A;  4KB6 A;  4K9B A;  4WQK A;  2ZH2 A;  1Q79 A;  4WQL A;  4LEV A;  2B56 A;  1FA0 A;  2ZH4 A;  4NXU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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