4KM5A

X-ray crystal structure of human cyclic gmp-amp synthase (cgas)
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
362
structure length
362
Chain Sequence
GASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNTGSYYEHVKISAPNEFDVMFKLEVPRIQLEEYSNTRAYYFVKFKRNPKENPLSQFLEGEILSASKMLSKFRKIIKEEINDIKDTDVIMKRKRGGSPAVTLLISEKISVDITLALESKSSWPASTQEGLRIQNWLSAKVRKQLRLKPFYLVPKHAKEGNGFQEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCRKDCLKLMKYLLEQLKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWDRKDLGLCFDNCVTYFLQCLRTEKLENYFIPEFNLFSSNLIDKRSKEFLTKQIEYERNNEFPVFDEF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords Cyclic GMP-AMP synthase
publication title Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity.
pubmed doi rcsb
source organism Homo sapiens
total genus 105
structure length 362
sequence length 362
ec nomenclature ec 2.7.7.86: Cyclic GMP-AMP synthase.
pdb deposition date 2013-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03281 Mab-21 Mab-21 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1410.40 Mainly Alpha Orthogonal Bundle Poly(a)-polymerase, middle domain Poly(a)-polymerase, middle domain 4km5A01
3.30.460.90 Alpha Beta 2-Layer Sandwich Beta Polymerase; domain 2 Beta Polymerase; domain 2 4km5A02
4O67A 4OAHA 4LEWA 4K99A 4LEZA 4JLZA 4OAGA 4NXWA 4LEVA 4MKPA 4AT9A 4AT7A 4O69A 4K96A 4ATBB 4K98A 4K8VA 4LEYA 4O68A 4WOYA 4AT8A 4KB6A 4NXTA 4K9BA 4K97A 4OAFA 4JLXA 4OAIZ 4KM5A 4K9AA 4AT9B 4AT7B 4NXXA 4NXUA 4AT8B 4NXVA 4ATBA 4O6AA
chains in the Genus database with same CATH superfamily
4FHWA 2ID1A 3MDCA 4DOBA 2VANA 5HRIA 1JQRA 5CB1A 4KLQA 3CK6A 3JZ0A 3C5FA 3GDXA 2DVIA 1ZQZA 1R8CA 1ZQDA 4WOYA 2ZH5A 2M2WA 5J0RA 2HN1A 4AT8A 9ICNA 4WQKA 5J2FA 4WC0A 4LVSA 9ICWA 1GPJA 2DR9A 1ZQSA 1ZQHA 4WCWA 5BPCA 2DR5A 3OGUA 3HWTA 4KLUA 4UBCA 8ICWA 3RJEA 4P4PA 3RJIA 8ICLA 5J0WA 3EF2A 4WC3A 4R66A 1ZQBA 5DBBA 4NLNA 4R64A 4JWNA 3C2MA 4MF2A 4YD2A 3AU6A 5J2GA 1WOTA 4YMOA 3C2KA 8ICQA 5IILA 3RJHA 1V4AA 2PXIA 4NKTA 3TFRA 4QZBA 4NKUA 3L9DA 5IIJA 8ICAA 5CFTA 7ICEA 2BE3A 3AQNA 4QZGA 2ISPA 2IHOA 4KLOA 4I29A 4LEWA 1VFGA 8ICCA 3MCRA 5J2CA 2BPGA 4RPXA 1NO5A 3RH5A 2ZH7A 5CFSA 9ICEA 5D61A 4FH3A 3HIYA 2ZH9A 2GWSA 4K4IA 2FMPA 5HC9A 4ATBB 4X4NA 4RQ8A 1XSNA 2BCVA 8ICFA 4UD5A 4WQLA 1JAJA 4Z6DA 4Z6EA 5F2VO 2IHMA 4RWOA 2BCQA 4RQ6A 4HX0A 3UQ0A 5DBAA 3K7DA 1NOMA 3MGHA 5DDMA 4XUSA 1ZQJA 4QZFA 3C5GA 3JPSA 9ICSA 4M2YA 4PGYA 1Q79A 4EBJA 2PBEA 2BCRA 4WC1A 4IQTA 2PFQA 4NM2A 4X5VA 2EWRA 2BCSA 3UXPA 4OAFA 4DOCA 4F5QA 2DRAA 4K4GA 1MIWA 1ZJNA 7ICNA 7ICGA 1ZQUA 5D46A 5DKWA 1ZJMA 8ICYA 4YMMA 3TFSA 4EEDA 7ICOA 4O5KA 2NRKA 9ICFA 3B0YA 3NVOA 4KLFA 4PHAA 1XSLA 4F5NA 5J0YA 4UB2A 4PGXA 4X4QA 4QZEA 9ICOA 4KLSA 2B51A 4I2BA 8ICRA 9ICCA 4GXKA 4OAIZ 4WBZA 4NXZA 5CA7A 4O9MA 1ZQNA 2GA9D 4P4OA 4NXXA 4M9LA 3AQLA 5CR0A 4MFAA 4M0AA 8ICBA 4PGQA 3WFRE 7ICPA 3UQ2A 1MIVA 7ICIA 5CJ7A 2DR8A 5D49A 1ZQCA 9ICLA 4JLZA 4FHVA 2PFNA 4WC5A 3ERCC 2GAFD 2I9GA 4XQ8A 2BBJA 3NKUA 4M04A 7ICMA 1HUZA 4XRHA 4NXTA 4K9BA 4KLGA 5DB6A 3NWIA 1R8BA 3HW8A 4X4TA 5J0OA 3PNCA 4NLKA 3LK9A 2B56A 4IQVA 4RQ2A 3HJ4A 1ZQYA 3PMLA 4O67A 1F5AA 4I0UA 3UPQA 3OVAA 4EEBA 4UAWA 7ICUA 4OAGA 4FO1A 3V72A 9ICIA 2ISOA 4F5PA 5DDYA 9ICKA 3WFQE 2B4VA 1MQ3A 7ICFA 4M9HA 4JLXA 1R89A 4KM5A 1TFYA 5J29A 5J0QA 1BPEA 7ICQA 4KLEA 5IIOA 4M47A 4ATBA 4UD4A 4IG8A 4P4MA 4QZ9A 4UAZA 4K99A 4RQ7A 1ZQEA 2M2UA 5IIMA 5J2AA 9ICTA 4KLMA 1BPZA 5DECA 5HRGA 1MQ2A 4UB3A 2RFFA 1ZQFA 4I28A 4PHDA 4R63A 2O5AA 4WBYA 3RH4A 3JPTA 4KLTA 4KB6A 4JWMA 1YLQA 4DO9A 1UETA 4K9AA 4LZGA 4YMNA 4EGWA 2BCUA 1ZQRA 2ZHAA 4I2EA 1ZQIA 5J2KA 3WFPA 2PFPA 9ICUA 4WC2A 3ISDA 4I2DA 4QZ8A 4RQ0A 4GXJA 4I27A 2BPCA 3H3AA 4I2GA 4XQ7A 3UXOA 4K98A 4LEYA 5HR9A 1XSPA 4MFCA 4RPYA 3JPQA 2HN2A 1R8AA 8ICHA 3WFOA 4TUPA 8ICOA 1ZQKA 4WH5A 4YCXA 1UEVA 4UB4A 3OWGA 5DBCA 4RQ5A 1BPDA 4MF8A 3OV7A 4KLLA 2DRBA 4KLJA 8ICGA 4LEZA 2FCLA 5D4BA 4NM1A 1KEJA 5DB9A 3ISBA 4P2HA 3ISCA 3B0XA 4FHXA 1HUOA 3WFSC 3UPSA 1FA0A 5CFUA 4K8VA 3H38A 2Q66A 4EBKA 4DOAA 3AUOA 3JCFA 5BOMA 4RWPA 4X4PA 4IQWA 4M9NA 4KLIA 5DEDA 1UEUA 2ZH8A 5DB7A 4E7XA 4X4VA 2IUBA 5EOZA 3C18A 5CHEA 4YN4A 3RJJA 2ZH3A 5D63A 5TZVA 5J2HA 2ZHBA 1MIYA 3AQKA 3OVBA 4TUSA 4I2CA 4FHYA 7ICVA 3ER9B 4MFFA 5J2DA 9ICMA 4RQ4A 3PMNA 9ICVA 8ICTA 4PHEA 4I2FA 3MBYA 3V7LA 4I2JA 1ZQMA 4RQ3A 5BOLA 4I2AA 4UB5A 8ICMA 5J2JA 3AQMA 5DB8A 7ICLA 5CWRA 3V7KA 3HJ1A 3OUYA 1JN3A 8ICPA 1JMSA 2HHPA 4F5RA 3MGIA 4M5DA 5HRBA 4NY8A 4TUQA 8ICEA 4NXWA 4X4UA 9ICGA 5J0XA 4QZDA 4X0AA 7ICTA 4LEVA 4Z6FA 4LZDA 3OUYB 8ICZA 2ZH6A 4O68A 5D62A 3MDAA 4RT3A 2FMSA 1TVAA 5IIIA 4WC4A 9ICJA 8ICUA 4PHPA 4RWNA 4IQUA 5HRDA 3C2LA 2BPFA 7ICKA 4UBBA 4WC6A 5CP2A 1ZQQA 3ER8C 1ZQVA 1RZTA 4M9JA 4R65A 4F5OA 3PHZA 2ZH2A 2M2VA 3JPOA 1RPLA 4NXUA 4AT8B 4K4HA 3H37A 4M9GA 4O6AA 4RT2A 5B3PA 4OAHA 3JPRA 4O5EA 5HRKA 9ICQA 9ICPA 4RPZA 3H39A 1ZQXA 4PH5A 1KDHA 5B3QA 4FH5A 4AT9A 4RWQA 1OU5A 8ICXA 4S3NA 2P66A 8ICNA 3C66A 1Q78A 5J0PA 4N7RA 5J2EA 1BPXA 4UB1A 5HHHA 1ZQPA 5HREA 4AT9B 4X4SA 5J0UA 4XA5A 9ICRA 2FMQA 1ZQAA 4FO6A 1KNYA 2W9MA 9ICXA 7ICHA 4FHPA 5J2IA 4MKPA 2DR7A 2PFOA 4LT6A 9ICAA 1TFWA 5IIKA 1ZQTA 4E8FA 4X4RA 4X4OA 4KLDA 1ZQLA 4UAYA 8ICVA 8ICKA 5HRLA 7ICRA 4WC7A 1BPBA 7ICJA 3LQCB 3JYYA 4NLZA 7ICSA 4AT7A 4O69A 4K96A 5HRFA 5HRHA 4QZIA 4TURA 1ZQOA 4O5CA 3JPNA 1ZQGA 4Z6CA 2ZH1A 4K97A 2O1PA 3RJKA 8ICSA 1BPYA 8ICJA 3RJGA 4EP7A 4AT7B 3JPPA 3OVSA 4NXVA 4GXIA 4PPXA 3NYBA 5CHGA 1VJ7A 4QZHA 3HX0A 4XJEA 5HHIA 4EV6A 4QZCA 5J0TA 4KLHA 9ICHA 1ZQWA 4X0BA 9ICBA 5JTGA 3V7JA 3RH6A 4YD1A 4E80A 8ICIA 3UXNA 5J0SA 4I2IA 2ZH4A 1TV9A 4I2HA 3AU2A 5IINA 4RQ1A 2M2TA 1PX5A 2BBHA 5J2BA 3RJFA 4QZAA 3K75D
chains in the Genus database with same CATH topology
4FHWA 5B3PA 4OAHA 2DVIA 4FH5A 4AT9A 5B3QA 4K98A 1R8CA 4LEYA 4X4QA 4WOYA 2ZH5A 3C66A 1Q78A 4AT8A 2B51A 4WQKA 4N7RA 1GPJA 1R8AA 2DR9A 4OAIZ 2GA9D 2DR5A 4AT9B 4WH5A 4NXXA 1UEVA 3OWGA 4X4SA 3OV7A 2DRBA 2DR8A 4LEZA 2FCLA 3EF2A 4JLZA 4FHVA 4FHPA 4MKPA 2DR7A 3ERCC 4LT6A 2GAFD 4FHXA 1FA0A 5CFUA 4K8VA 1TFWA 2Q66A 3NKUA 4NKTA 4NXTA 4K9BA 4X4PA 4E8FA 4X4RA 4X4OA 1R8BA 4NKUA 1UEUA 2ZH8A 4E7XA 4X4TA 4X4VA 5CFTA 5CHEA 2B56A 3HJ4A 2IHOA 2ZH3A 4O67A 1F5AA 5D63A 4LEWA 3OVAA 3MCRA 2ZHBA 3OVBA 4FHYA 4OAGA 2ZH7A 5CFSA 3ER9B 5D61A 4FH3A 3HIYA 2ZH9A 4FO1A 4AT7A 4O69A 4K96A 4ATBB 4X4NA 2B4VA 4UD5A 4WQLA 2ZH1A 4K97A 2O1PA 4JLXA 1R89A 4KM5A 1TFYA 4EP7A 4AT7B 3HJ1A 3OUYA 3OVSA 4HX0A 4NXVA 4ATBA 2HHPA 4UD4A 3NYBA 4M5DA 4K99A 3K7DA 4NXWA 4XJEA 4X4UA 4LEVA 1Q79A 3OUYB 2ZH6A 4O68A 5D62A 4KB6A 2EWRA 4E80A 4OAFA 1UETA 2ZH4A 4K9AA 2DRAA 2ZHAA 3ER8C 3PHZA 2ZH2A 4NXUA 4AT8B 4O6AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4O67 A;  4OAH A;  4LEW A;  4K99 A;  4LEZ A;  4JLZ A;  4OAG A;  4NXW A;  4LEV A;  4MKP A;  4AT9 A;  4AT7 A;  4O69 A;  4K96 A;  4ATB B;  4K98 A;  4K8V A;  4LEY A;  4O68 A;  4WOY A;  4AT8 A;  4KB6 A;  4NXT A;  4K9B A;  4K97 A;  4OAF A;  4JLX A;  4OAI Z;  4KM5 A;  4K9A A;  4AT9 B;  4AT7 B;  4NXX A;  4NXU A;  4AT8 B;  4NXV A;  4ATB A;  4O6A A; 
#chains in the Genus database with same CATH topology
 4FHW A;  2ID1 A;  3MDC A;  4DOB A;  2VAN A;  5HRI A;  1JQR A;  5CB1 A;  4KLQ A;  3CK6 A;  3JZ0 A;  3C5F A;  3GDX A;  2DVI A;  1ZQZ A;  1R8C A;  1ZQD A;  4WOY A;  2ZH5 A;  2M2W A;  5J0R A;  2HN1 A;  4AT8 A;  9ICN A;  4WQK A;  5J2F A;  4WC0 A;  4LVS A;  9ICW A;  1GPJ A;  2DR9 A;  1ZQS A;  1ZQH A;  4WCW A;  5BPC A;  2DR5 A;  3OGU A;  3HWT A;  4KLU A;  4UBC A;  8ICW A;  3RJE A;  4P4P A;  3RJI A;  8ICL A;  5J0W A;  3EF2 A;  4WC3 A;  4R66 A;  1ZQB A;  5DBB A;  4NLN A;  4R64 A;  4JWN A;  3C2M A;  4MF2 A;  4YD2 A;  3AU6 A;  5J2G A;  1WOT A;  4YMO A;  3C2K A;  8ICQ A;  5IIL A;  3RJH A;  1V4A A;  2PXI A;  4NKT A;  3TFR A;  4QZB A;  4NKU A;  3L9D A;  5IIJ A;  8ICA A;  5CFT A;  7ICE A;  2BE3 A;  3AQN A;  4QZG A;  2ISP A;  2IHO A;  4KLO A;  4I29 A;  4LEW A;  1VFG A;  8ICC A;  3MCR A;  5J2C A;  2BPG A;  4RPX A;  1NO5 A;  3RH5 A;  2ZH7 A;  5CFS A;  9ICE A;  5D61 A;  4FH3 A;  3HIY A;  2ZH9 A;  2GWS A;  4K4I A;  2FMP A;  5HC9 A;  4ATB B;  4X4N A;  4RQ8 A;  1XSN A;  2BCV A;  8ICF A;  4UD5 A;  4WQL A;  1JAJ A;  4Z6D A;  4Z6E A;  5F2V O;  2IHM A;  4RWO A;  2BCQ A;  4RQ6 A;  4HX0 A;  3UQ0 A;  5DBA A;  3K7D A;  1NOM A;  3MGH A;  5DDM A;  4XUS A;  1ZQJ A;  4QZF A;  3C5G A;  3JPS A;  9ICS A;  4M2Y A;  4PGY A;  1Q79 A;  4EBJ A;  2PBE A;  2BCR A;  4WC1 A;  4IQT A;  2PFQ A;  4NM2 A;  4X5V A;  2EWR A;  2BCS A;  3UXP A;  4OAF A;  4DOC A;  4F5Q A;  2DRA A;  4K4G A;  1MIW A;  1ZJN A;  7ICN A;  7ICG A;  1ZQU A;  5D46 A;  5DKW A;  1ZJM A;  8ICY A;  4YMM A;  3TFS A;  4EED A;  7ICO A;  4O5K A;  2NRK A;  9ICF A;  3B0Y A;  3NVO A;  4KLF A;  4PHA A;  1XSL A;  4F5N A;  5J0Y A;  4UB2 A;  4PGX A;  4X4Q A;  4QZE A;  9ICO A;  4KLS A;  2B51 A;  4I2B A;  8ICR A;  9ICC A;  4GXK A;  4OAI Z;  4WBZ A;  4NXZ A;  5CA7 A;  4O9M A;  1ZQN A;  2GA9 D;  4P4O A;  4NXX A;  4M9L A;  3AQL A;  5CR0 A;  4MFA A;  4M0A A;  8ICB A;  4PGQ A;  3WFR E;  7ICP A;  3UQ2 A;  1MIV A;  7ICI A;  5CJ7 A;  2DR8 A;  5D49 A;  1ZQC A;  9ICL A;  4JLZ A;  4FHV A;  2PFN A;  4WC5 A;  3ERC C;  2GAF D;  2I9G A;  4XQ8 A;  2BBJ A;  3NKU A;  4M04 A;  7ICM A;  1HUZ A;  4XRH A;  4NXT A;  4K9B A;  4KLG A;  5DB6 A;  3NWI A;  1R8B A;  3HW8 A;  4X4T A;  5J0O A;  3PNC A;  4NLK A;  3LK9 A;  2B56 A;  4IQV A;  4RQ2 A;  3HJ4 A;  1ZQY A;  3PML A;  4O67 A;  1F5A A;  4I0U A;  3UPQ A;  3OVA A;  4EEB A;  4UAW A;  7ICU A;  4OAG A;  4FO1 A;  3V72 A;  9ICI A;  2ISO A;  4F5P A;  5DDY A;  9ICK A;  3WFQ E;  2B4V A;  1MQ3 A;  7ICF A;  4M9H A;  4JLX A;  1R89 A;  4KM5 A;  1TFY A;  5J29 A;  5J0Q A;  1BPE A;  7ICQ A;  4KLE A;  5IIO A;  4M47 A;  4ATB A;  4UD4 A;  4IG8 A;  4P4M A;  4QZ9 A;  4UAZ A;  4K99 A;  4RQ7 A;  1ZQE A;  2M2U A;  5IIM A;  5J2A A;  9ICT A;  4KLM A;  1BPZ A;  5DEC A;  5HRG A;  1MQ2 A;  4UB3 A;  2RFF A;  1ZQF A;  4I28 A;  4PHD A;  4R63 A;  2O5A A;  4WBY A;  3RH4 A;  3JPT A;  4KLT A;  4KB6 A;  4JWM A;  1YLQ A;  4DO9 A;  1UET A;  4K9A A;  4LZG A;  4YMN A;  4EGW A;  2BCU A;  1ZQR A;  2ZHA A;  4I2E A;  1ZQI A;  5J2K A;  3WFP A;  2PFP A;  9ICU A;  4WC2 A;  3ISD A;  4I2D A;  4QZ8 A;  4RQ0 A;  4GXJ A;  4I27 A;  2BPC A;  3H3A A;  4I2G A;  4XQ7 A;  3UXO A;  4K98 A;  4LEY A;  5HR9 A;  1XSP A;  4MFC A;  4RPY A;  3JPQ A;  2HN2 A;  1R8A A;  8ICH A;  3WFO A;  4TUP A;  8ICO A;  1ZQK A;  4WH5 A;  4YCX A;  1UEV A;  4UB4 A;  3OWG A;  5DBC A;  4RQ5 A;  1BPD A;  4MF8 A;  3OV7 A;  4KLL A;  2DRB A;  4KLJ A;  8ICG A;  4LEZ A;  2FCL A;  5D4B A;  4NM1 A;  1KEJ A;  5DB9 A;  3ISB A;  4P2H A;  3ISC A;  3B0X A;  4FHX A;  1HUO A;  3WFS C;  3UPS A;  1FA0 A;  5CFU A;  4K8V A;  3H38 A;  2Q66 A;  4EBK A;  4DOA A;  3AUO A;  3JCF A;  5BOM A;  4RWP A;  4X4P A;  4IQW A;  4M9N A;  4KLI A;  5DED A;  1UEU A;  2ZH8 A;  5DB7 A;  4E7X A;  4X4V A;  2IUB A;  5EOZ A;  3C18 A;  5CHE A;  4YN4 A;  3RJJ A;  2ZH3 A;  5D63 A;  5TZV A;  5J2H A;  2ZHB A;  1MIY A;  3AQK A;  3OVB A;  4TUS A;  4I2C A;  4FHY A;  7ICV A;  3ER9 B;  4MFF A;  5J2D A;  9ICM A;  4RQ4 A;  3PMN A;  9ICV A;  8ICT A;  4PHE A;  4I2F A;  3MBY A;  3V7L A;  4I2J A;  1ZQM A;  4RQ3 A;  5BOL A;  4I2A A;  4UB5 A;  8ICM A;  5J2J A;  3AQM A;  5DB8 A;  7ICL A;  5CWR A;  3V7K A;  3HJ1 A;  3OUY A;  1JN3 A;  8ICP A;  1JMS A;  2HHP A;  4F5R A;  3MGI A;  4M5D A;  5HRB A;  4NY8 A;  4TUQ A;  8ICE A;  4NXW A;  4X4U A;  9ICG A;  5J0X A;  4QZD A;  4X0A A;  7ICT A;  4LEV A;  4Z6F A;  4LZD A;  3OUY B;  8ICZ A;  2ZH6 A;  4O68 A;  5D62 A;  3MDA A;  4RT3 A;  2FMS A;  1TVA A;  5III A;  4WC4 A;  9ICJ A;  8ICU A;  4PHP A;  4RWN A;  4IQU A;  5HRD A;  3C2L A;  2BPF A;  7ICK A;  4UBB A;  4WC6 A;  5CP2 A;  1ZQQ A;  3ER8 C;  1ZQV A;  1RZT A;  4M9J A;  4R65 A;  4F5O A;  3PHZ A;  2ZH2 A;  2M2V A;  3JPO A;  1RPL A;  4NXU A;  4AT8 B;  4K4H A;  3H37 A;  4M9G A;  4O6A A;  4RT2 A;  5B3P A;  4OAH A;  3JPR A;  4O5E A;  5HRK A;  9ICQ A;  9ICP A;  4RPZ A;  3H39 A;  1ZQX A;  4PH5 A;  1KDH A;  5B3Q A;  4FH5 A;  4AT9 A;  4RWQ A;  1OU5 A;  8ICX A;  4S3N A;  2P66 A;  8ICN A;  3C66 A;  1Q78 A;  5J0P A;  4N7R A;  5J2E A;  1BPX A;  4UB1 A;  5HHH A;  1ZQP A;  5HRE A;  4AT9 B;  4X4S A;  5J0U A;  4XA5 A;  9ICR A;  2FMQ A;  1ZQA A;  4FO6 A;  1KNY A;  2W9M A;  9ICX A;  7ICH A;  4FHP A;  5J2I A;  4MKP A;  2DR7 A;  2PFO A;  4LT6 A;  9ICA A;  1TFW A;  5IIK A;  1ZQT A;  4E8F A;  4X4R A;  4X4O A;  4KLD A;  1ZQL A;  4UAY A;  8ICV A;  8ICK A;  5HRL A;  7ICR A;  4WC7 A;  1BPB A;  7ICJ A;  3LQC B;  3JYY A;  4NLZ A;  7ICS A;  4AT7 A;  4O69 A;  4K96 A;  5HRF A;  5HRH A;  4QZI A;  4TUR A;  1ZQO A;  4O5C A;  3JPN A;  1ZQG A;  4Z6C A;  2ZH1 A;  4K97 A;  2O1P A;  3RJK A;  8ICS A;  1BPY A;  8ICJ A;  3RJG A;  4EP7 A;  4AT7 B;  3JPP A;  3OVS A;  4NXV A;  4GXI A;  4PPX A;  3NYB A;  5CHG A;  1VJ7 A;  4QZH A;  3HX0 A;  4XJE A;  5HHI A;  4EV6 A;  4QZC A;  5J0T A;  4KLH A;  9ICH A;  1ZQW A;  4X0B A;  9ICB A;  5JTG A;  3V7J A;  3RH6 A;  4YD1 A;  4E80 A;  8ICI A;  3UXN A;  5J0S A;  4I2I A;  2ZH4 A;  1TV9 A;  4I2H A;  3AU2 A;  5IIN A;  4RQ1 A;  2M2T A;  1PX5 A;  2BBH A;  5J2B A;  3RJF A;  4QZA A;  3K75 D; 
#chains in the Genus database with same CATH homology
 4FHW A;  5B3P A;  4OAH A;  2DVI A;  4FH5 A;  4AT9 A;  5B3Q A;  4K98 A;  1R8C A;  4LEY A;  4X4Q A;  4WOY A;  2ZH5 A;  3C66 A;  1Q78 A;  4AT8 A;  2B51 A;  4WQK A;  4N7R A;  1GPJ A;  1R8A A;  2DR9 A;  4OAI Z;  2GA9 D;  2DR5 A;  4AT9 B;  4WH5 A;  4NXX A;  1UEV A;  3OWG A;  4X4S A;  3OV7 A;  2DRB A;  2DR8 A;  4LEZ A;  2FCL A;  3EF2 A;  4JLZ A;  4FHV A;  4FHP A;  4MKP A;  2DR7 A;  3ERC C;  4LT6 A;  2GAF D;  4FHX A;  1FA0 A;  5CFU A;  4K8V A;  1TFW A;  2Q66 A;  3NKU A;  4NKT A;  4NXT A;  4K9B A;  4X4P A;  4E8F A;  4X4R A;  4X4O A;  1R8B A;  4NKU A;  1UEU A;  2ZH8 A;  4E7X A;  4X4T A;  4X4V A;  5CFT A;  5CHE A;  2B56 A;  3HJ4 A;  2IHO A;  2ZH3 A;  4O67 A;  1F5A A;  5D63 A;  4LEW A;  3OVA A;  3MCR A;  2ZHB A;  3OVB A;  4FHY A;  4OAG A;  2ZH7 A;  5CFS A;  3ER9 B;  5D61 A;  4FH3 A;  3HIY A;  2ZH9 A;  4FO1 A;  4AT7 A;  4O69 A;  4K96 A;  4ATB B;  4X4N A;  2B4V A;  4UD5 A;  4WQL A;  2ZH1 A;  4K97 A;  2O1P A;  4JLX A;  1R89 A;  4KM5 A;  1TFY A;  4EP7 A;  4AT7 B;  3HJ1 A;  3OUY A;  3OVS A;  4HX0 A;  4NXV A;  4ATB A;  2HHP A;  4UD4 A;  3NYB A;  4M5D A;  4K99 A;  3K7D A;  4NXW A;  4XJE A;  4X4U A;  4LEV A;  1Q79 A;  3OUY B;  2ZH6 A;  4O68 A;  5D62 A;  4KB6 A;  2EWR A;  4E80 A;  4OAF A;  1UET A;  2ZH4 A;  4K9A A;  2DRA A;  2ZHA A;  3ER8 C;  3PHZ A;  2ZH2 A;  4NXU A;  4AT8 B;  4O6A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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