4LEWA

Structure of human cgas
Total Genus 117
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
117
sequence length
364
structure length
362
Chain Sequence
DAAPGASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNTGYEHVKISAPNEFDVMFKLEVPRIQLEEYSNTRAYYFVKFKRNPKENPLSQFLEGEILSASKMLSKFRKIIKEEINDIKDTDVIMKRKRGGSPAVTLLISEKISVDITLALESKSSWPASTQEGLRIQNWLSAKVRKQLRLKPFYLVPKHAKEGNGFQEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCRKDCLKLMKYLLEQLKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWDRKDLGLCFDNCVTYFLQCLRTEKLENYFIPEFNLFSSNLIDKRSKEFLTKQIEYERNNEFPVFD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Cyclic GMP-AMP synthase
total genus 117
structure length 362
sequence length 364
chains with identical sequence B
ec nomenclature ec 2.7.7.86: Cyclic GMP-AMP synthase.
pdb deposition date 2013-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03281 Mab-21 Mab-21 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1410.40 Mainly Alpha Orthogonal Bundle Poly(a)-polymerase, middle domain Poly(a)-polymerase, middle domain 4lewA01
3.30.460.90 Alpha Beta 2-Layer Sandwich Beta Polymerase; domain 2 Beta Polymerase; domain 2 4lewA02
4AT9B 4K9AA 4OAGA 4AT8B 4K97A 4LEVA 4O68A 4MKPA 4KB6A 4K98A 4OAFA 4ATBB 4O69A 4KM5A 4AT7A 4OAIZ 4K9BA 4NXVA 4LEWA 4JLZA 4NXUA 4AT9A 4AT8A 4LEZA 4LEYA 4O67A 4K96A 4K8VA 4NXXA 4O6AA 4K99A 4AT7B 4NXTA 4ATBA 4OAHA 4JLXA 4WOYA 4NXWA
chains in the Genus database with same CATH superfamily
4AT9B 4GXIA 3OV7A 1ZQVA 2W9MA 2VANA 4KLUA 4P4MA 5J2EA 4M47A 4YCXA 4O68A 4UAWA 4YMMA 5DEDA 4GXJA 4KB6A 4DOAA 9ICBA 1ZQCA 4ATBB 4M9LA 4X4PA 4UB5A 4RWNA 4KLJA 4AT9A 3MDCA 4RPYA 1TFYA 5DDYA 4EGWA 1R8BA 4E7XA 2O5AA 4TUPA 5J0OA 8ICHA 1ZQRA 4RQ3A 4FH3A 4XQ7A 2RFFA 3MBYA 4FHWA 4ATBA 3RH5A 5J2GA 4MFFA 4NXWA 3OVSA 5J2DA 1UETA 5J2CA 4K97A 4IG8A 4X4NA 9ICAA 1GPJA 4UB2A 1ZQOA 4M04A 4I28A 7ICEA 5DB7A 8ICAA 4LT6A 4WC3A 4UBBA 4K9BA 3RJHA 4X4QA 1ZQZA 4Z6EA 9ICCA 2BPCA 4NM1A 8ICRA 5HRFA 5J2KA 1XSNA 4PPXA 1JAJA 1R8AA 1VJ7A 4QZIA 4M9JA 4FHYA 2DR8A 3UXOA 2HN1A 1NO5A 1ZQBA 7ICUA 4X4RA 4NKUA 2PXIA 1ZQGA 3OVBA 1KEJA 1ZQXA 2BCQA 5CR0A 3PMLA 8ICCA 4P4OA 3GDXA 9ICQA 4M0AA 4I2DA 1BPDA 7ICVA 4YMOA 4UAZA 7ICHA 5IIIA 5CA7A 9ICFA 2ISOA 5HHIA 3C5FA 7ICNA 4P4PA 4UB3A 2GA9D 4KLEA 4RQ1A 3MGHA 4DOBA 4O9MA 5CFSA 4WOYA 4F5OA 4K9AA 4XQ8A 5BOMA 4LEVA 3JYYA 1R8CA 5F2VO 5J0YA 1ZQEA 4I2CA 3H39A 9ICVA 2IHOA 8ICVA 4QZCA 4RT3A 1ZQWA 5IINA 2DR7A 4QZDA 3C2KA 1MIWA 4FO1A 4RQ8A 3L9DA 5CWRA 4RQ4A 9ICUA 5J2BA 4IQUA 4JWMA 8ICEA 3JCFA 4K4IA 1HUZA 8ICZA 4WC7A 7ICOA 9ICKA 1FA0A 2BBHA 3JPRA 5J0RA 3NYBA 5J2AA 2PFNA 5CB1A 7ICGA 8ICIA 4RWPA 4NLZA 3RJKA 9ICIA 4KLQA 7ICSA 1BPEA 9ICRA 4FHPA 3JPQA 5D49A 4EBKA 5BOLA 5HRHA 1JQRA 4X4TA 9ICEA 4K96A 4RPZA 9ICLA 4Z6DA 2DRAA 1TFWA 4F5RA 1ZQLA 8ICKA 4UB1A 3B0XA 5J0XA 4X4SA 3JPSA 1R89A 9ICTA 2ZHBA 5D62A 2ZH6A 4MKPA 3MGIA 5HC9A 4OAFA 3ERCC 1RPLA 3UPSA 1HUOA 4F5NA 8ICQA 3K75D 5IIJA 3OUYB 9ICXA 5HRKA 4QZEA 4TUQA 2M2VA 3K7DA 4F5PA 7ICFA 3NWIA 4KLMA 3PNCA 4Z6CA 4WC4A 4I2GA 4WQKA 4K8VA 3C5GA 3CK6A 4Z6FA 1ZQDA 3ISDA 5J2HA 4OAHA 1XSLA 3OGUA 4K4GA 5CHEA 2ZHAA 4OAGA 3OUYA 3B0YA 1TVAA 3AQMA 4E80A 4XRHA 4RWOA 3TFSA 4XUSA 4EEBA 5D61A 1ZQQA 4X0AA 5JTGA 5DB6A 5J0SA 4YN4A 3UPQA 5IIOA 3MCRA 9ICWA 5HRBA 2ZH9A 3RJGA 2ZH3A 3RJFA 2Q66A 5J2IA 4WC0A 1ZQAA 5CHGA 3PHZA 4WH5A 4PHAA 1Q78A 4IQTA 5EOZA 9ICOA 5J0WA 4QZ8A 3HIYA 1MIYA 2HN2A 4EP7A 4EEDA 5IIMA 5IIKA 4NXVA 4LEWA 5D46A 4UBCA 3UQ0A 4I2EA 2O1PA 9ICNA 5HR9A 5BPCA 9ICMA 4E8FA 3OVAA 4I2JA 4N7RA 3C18A 4R63A 4O5CA 2ZH8A 4JLXA 2FMPA 4HX0A 3MDAA 1WOTA 3NVOA 1ZQTA 4FHVA 5J2FA 3RJEA 4MF8A 8ICJA 4KLHA 2BPGA 3AQKA 3V7KA 4F5QA 1MIVA 4MFCA 2EWRA 4R64A 4NLKA 4M9GA 4WC5A 8ICLA 4QZ9A 4RQ7A 1ZQYA 3WFSC 5J0TA 5CJ7A 4AT7B 4NXZA 4NXTA 4TUSA 2BPFA 3ISCA 5DECA 4QZBA 4LEYA 3RH4A 9ICGA 2ZH4A 4YMNA 8ICMA 4RQ6A 3RH6A 1RZTA 1JN3A 5DB9A 5HREA 4I2BA 4PGYA 4O5KA 4P2HA 8ICPA 4KLDA 3H37A 4FO6A 3JPNA 4PHDA 4AT7A 4X4VA 4YD2A 2BCUA 3ER8C 3AQLA 4RQ5A 5DBBA 4I2AA 4I2IA 1YLQA 3HJ1A 2B56A 1ZJMA 4RWQA 2ZH2A 4RQ2A 4XA5A 2FMSA 4I2FA 5DDMA 4UD4A 2HHPA 5CFTA 2DRBA 4X4UA 8ICBA 4AT8B 1KNYA 4KLTA 1UEUA 5J29A 2BE3A 4LZGA 1BPXA 7ICKA 4I29A 5J0PA 9ICSA 5DBCA 4RQ0A 2PBEA 1XSPA 5J0QA 1MQ2A 1F5AA 4M5DA 1BPBA 1MQ3A 4PHEA 4QZAA 4AT8A 4LVSA 5D63A 2ZH1A 1TV9A 5D4BA 4R65A 3H38A 3HX0A 7ICTA 4UAYA 2P66A 4K98A 4GXKA 8ICUA 3AU6A 4LZDA 3UXNA 7ICMA 2I9GA 4I27A 4X4OA 2NRKA 2BCSA 8ICWA 9ICHA 2GAFD 1BPZA 3C2MA 2ISPA 4IQWA 4KLGA 3PMNA 9ICJA 5J0UA 2PFOA 1NOMA 2BBJA 4O67A 4MF2A 2M2TA 2DR5A 4NXXA 4EBJA 4RPXA 5IILA 4XJEA 1ZQKA 2BCRA 1ZQHA 7ICQA 3V7LA 4YD1A 4M9NA 4WC1A 3UXPA 7ICPA 3JPPA 2DR9A 4NM2A 1OU5A 2DVIA 1ZQFA 8ICSA 4O69A 3JZ0A 4OAIZ 2ID1A 8ICYA 3WFPA 4NXUA 3JPTA 1ZJNA 4FHXA 2FCLA 1ZQNA 1VFGA 4PH5A 1Q79A 4WC2A 2IHMA 1JMSA 4I0UA 4JWNA 4S3NA 5DBAA 4EV6A 4LEZA 4X5VA 3LQCB 2PFQA 4O6AA 4I2HA 4UB4A 4WCWA 4PGXA 2M2UA 2PFPA 1BPYA 3WFOA 3RJIA 2FMQA 2ZH7A 4QZHA 8ICXA 5DB8A 2B4VA 2IUBA 2M2WA 5TZVA 5HRLA 3V72A 3AUOA 5B3QA 1ZQPA 2BCVA 3C66A 4JLZA 3AQNA 4IQVA 4TURA 3ISBA 4PGQA 1ZQSA 4M9HA 4KLLA 4M2YA 1V4AA 1ZQMA 4QZFA 3RJJA 4WBZA 5HHHA 3TFRA 7ICJA 5HRDA 4NKTA 4QZGA 3HWTA 3HW8A 9ICPA 4DO9A 4WC6A 4WQLA 5CP2A 4K4HA 4RT2A 3EF2A 3C2LA 5CFUA 1PX5A 3WFQE 3UQ2A 2GWSA 1ZQJA 8ICTA 4FH5A 3AU2A 4KLFA 4DOCA 4MFAA 4KLIA 1UEVA 5B3PA 4K99A 1ZQUA 2ZH5A 4UD5A 3V7JA 4KLOA 8ICNA 4R66A 7ICIA 4O5EA 3OWGA 4PHPA 8ICGA 3ER9B 5DKWA 7ICLA 3JPOA 1ZQIA 5J2JA 5HRGA 4KLSA 4KM5A 3NKUA 5HRIA 8ICFA 4NY8A 2B51A 3HJ4A 4X0BA 4NLNA 3LK9A 7ICRA 8ICOA 3WFRE 1KDHA 4WBYA 3H3AA
chains in the Genus database with same CATH topology
4AT9B 4XJEA 4HX0A 3OV7A 1FA0A 4FHVA 3NYBA 2DR9A 4O68A 4KB6A 4ATBB 2DVIA 4X4PA 4O69A 4OAIZ 4AT9A 4NXUA 4FHPA 2EWRA 1TFYA 4FHXA 2FCLA 1R8BA 4E7XA 4X4TA 1Q79A 4K96A 2DRAA 4FH3A 4AT7B 1TFWA 4NXTA 4FHWA 4ATBA 4LEZA 4O6AA 4NXWA 4LEYA 2ZH4A 3OVSA 1UETA 4K97A 4X4NA 4X4SA 1GPJA 1R89A 2ZH7A 2ZHBA 5D62A 2ZH6A 2B4VA 4MKPA 4OAFA 3ERCC 4LT6A 4AT7A 4X4VA 5B3QA 4K9BA 3ER8C 3OUYB 4X4QA 3C66A 4JLZA 3HJ1A 2B56A 3K7DA 2ZH2A 4WQKA 4K8VA 4UD4A 1R8AA 2HHPA 4OAHA 5CFTA 2DRBA 4FHYA 2DR8A 5CHEA 2ZHAA 4X4UA 4NKTA 4OAGA 3OUYA 4AT8B 4X4RA 4NKUA 4WQLA 1UEUA 3OVBA 4E80A 3EF2A 5CFUA 5D61A 4FH5A 1F5AA 4M5DA 4AT8A 5D63A 2ZH1A 1UEVA 3MCRA 5B3PA 4K99A 2GA9D 2ZH9A 2ZH5A 4UD5A 5CFSA 4WOYA 2ZH3A 4K9AA 4K98A 2Q66A 3PHZA 4WH5A 1Q78A 4LEVA 1R8CA 3OWGA 3ER9B 4X4OA 2IHOA 3HIYA 2GAFD 4KM5A 4EP7A 3NKUA 4NXVA 4LEWA 2ZH8A 2DR7A 2O1PA 4FO1A 2B51A 3HJ4A 4O67A 2DR5A 4NXXA 4E8FA 3OVAA 4N7RA 4JLXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AT9 B;  4K9A A;  4OAG A;  4AT8 B;  4K97 A;  4LEV A;  4O68 A;  4MKP A;  4KB6 A;  4K98 A;  4OAF A;  4ATB B;  4O69 A;  4KM5 A;  4AT7 A;  4OAI Z;  4K9B A;  4NXV A;  4LEW A;  4JLZ A;  4NXU A;  4AT9 A;  4AT8 A;  4LEZ A;  4LEY A;  4O67 A;  4K96 A;  4K8V A;  4NXX A;  4O6A A;  4K99 A;  4AT7 B;  4NXT A;  4ATB A;  4OAH A;  4JLX A;  4WOY A;  4NXW A; 
#chains in the Genus database with same CATH topology
 4AT9 B;  4GXI A;  3OV7 A;  1ZQV A;  2W9M A;  2VAN A;  4KLU A;  4P4M A;  5J2E A;  4M47 A;  4YCX A;  4O68 A;  4UAW A;  4YMM A;  5DED A;  4GXJ A;  4KB6 A;  4DOA A;  9ICB A;  1ZQC A;  4ATB B;  4M9L A;  4X4P A;  4UB5 A;  4RWN A;  4KLJ A;  4AT9 A;  3MDC A;  4RPY A;  1TFY A;  5DDY A;  4EGW A;  1R8B A;  4E7X A;  2O5A A;  4TUP A;  5J0O A;  8ICH A;  1ZQR A;  4RQ3 A;  4FH3 A;  4XQ7 A;  2RFF A;  3MBY A;  4FHW A;  4ATB A;  3RH5 A;  5J2G A;  4MFF A;  4NXW A;  3OVS A;  5J2D A;  1UET A;  5J2C A;  4K97 A;  4IG8 A;  4X4N A;  9ICA A;  1GPJ A;  4UB2 A;  1ZQO A;  4M04 A;  4I28 A;  7ICE A;  5DB7 A;  8ICA A;  4LT6 A;  4WC3 A;  4UBB A;  4K9B A;  3RJH A;  4X4Q A;  1ZQZ A;  4Z6E A;  9ICC A;  2BPC A;  4NM1 A;  8ICR A;  5HRF A;  5J2K A;  1XSN A;  4PPX A;  1JAJ A;  1R8A A;  1VJ7 A;  4QZI A;  4M9J A;  4FHY A;  2DR8 A;  3UXO A;  2HN1 A;  1NO5 A;  1ZQB A;  7ICU A;  4X4R A;  4NKU A;  2PXI A;  1ZQG A;  3OVB A;  1KEJ A;  1ZQX A;  2BCQ A;  5CR0 A;  3PML A;  8ICC A;  4P4O A;  3GDX A;  9ICQ A;  4M0A A;  4I2D A;  1BPD A;  7ICV A;  4YMO A;  4UAZ A;  7ICH A;  5III A;  5CA7 A;  9ICF A;  2ISO A;  5HHI A;  3C5F A;  7ICN A;  4P4P A;  4UB3 A;  2GA9 D;  4KLE A;  4RQ1 A;  3MGH A;  4DOB A;  4O9M A;  5CFS A;  4WOY A;  4F5O A;  4K9A A;  4XQ8 A;  5BOM A;  4LEV A;  3JYY A;  1R8C A;  5F2V O;  5J0Y A;  1ZQE A;  4I2C A;  3H39 A;  9ICV A;  2IHO A;  8ICV A;  4QZC A;  4RT3 A;  1ZQW A;  5IIN A;  2DR7 A;  4QZD A;  3C2K A;  1MIW A;  4FO1 A;  4RQ8 A;  3L9D A;  5CWR A;  4RQ4 A;  9ICU A;  5J2B A;  4IQU A;  4JWM A;  8ICE A;  3JCF A;  4K4I A;  1HUZ A;  8ICZ A;  4WC7 A;  7ICO A;  9ICK A;  1FA0 A;  2BBH A;  3JPR A;  5J0R A;  3NYB A;  5J2A A;  2PFN A;  5CB1 A;  7ICG A;  8ICI A;  4RWP A;  4NLZ A;  3RJK A;  9ICI A;  4KLQ A;  7ICS A;  1BPE A;  9ICR A;  4FHP A;  3JPQ A;  5D49 A;  4EBK A;  5BOL A;  5HRH A;  1JQR A;  4X4T A;  9ICE A;  4K96 A;  4RPZ A;  9ICL A;  4Z6D A;  2DRA A;  1TFW A;  4F5R A;  1ZQL A;  8ICK A;  4UB1 A;  3B0X A;  5J0X A;  4X4S A;  3JPS A;  1R89 A;  9ICT A;  2ZHB A;  5D62 A;  2ZH6 A;  4MKP A;  3MGI A;  5HC9 A;  4OAF A;  3ERC C;  1RPL A;  3UPS A;  1HUO A;  4F5N A;  8ICQ A;  3K75 D;  5IIJ A;  3OUY B;  9ICX A;  5HRK A;  4QZE A;  4TUQ A;  2M2V A;  3K7D A;  4F5P A;  7ICF A;  3NWI A;  4KLM A;  3PNC A;  4Z6C A;  4WC4 A;  4I2G A;  4WQK A;  4K8V A;  3C5G A;  3CK6 A;  4Z6F A;  1ZQD A;  3ISD A;  5J2H A;  4OAH A;  1XSL A;  3OGU A;  4K4G A;  5CHE A;  2ZHA A;  4OAG A;  3OUY A;  3B0Y A;  1TVA A;  3AQM A;  4E80 A;  4XRH A;  4RWO A;  3TFS A;  4XUS A;  4EEB A;  5D61 A;  1ZQQ A;  4X0A A;  5JTG A;  5DB6 A;  5J0S A;  4YN4 A;  3UPQ A;  5IIO A;  3MCR A;  9ICW A;  5HRB A;  2ZH9 A;  3RJG A;  2ZH3 A;  3RJF A;  2Q66 A;  5J2I A;  4WC0 A;  1ZQA A;  5CHG A;  3PHZ A;  4WH5 A;  4PHA A;  1Q78 A;  4IQT A;  5EOZ A;  9ICO A;  5J0W A;  4QZ8 A;  3HIY A;  1MIY A;  2HN2 A;  4EP7 A;  4EED A;  5IIM A;  5IIK A;  4NXV A;  4LEW A;  5D46 A;  4UBC A;  3UQ0 A;  4I2E A;  2O1P A;  9ICN A;  5HR9 A;  5BPC A;  9ICM A;  4E8F A;  3OVA A;  4I2J A;  4N7R A;  3C18 A;  4R63 A;  4O5C A;  2ZH8 A;  4JLX A;  2FMP A;  4HX0 A;  3MDA A;  1WOT A;  3NVO A;  1ZQT A;  4FHV A;  5J2F A;  3RJE A;  4MF8 A;  8ICJ A;  4KLH A;  2BPG A;  3AQK A;  3V7K A;  4F5Q A;  1MIV A;  4MFC A;  2EWR A;  4R64 A;  4NLK A;  4M9G A;  4WC5 A;  8ICL A;  4QZ9 A;  4RQ7 A;  1ZQY A;  3WFS C;  5J0T A;  5CJ7 A;  4AT7 B;  4NXZ A;  4NXT A;  4TUS A;  2BPF A;  3ISC A;  5DEC A;  4QZB A;  4LEY A;  3RH4 A;  9ICG A;  2ZH4 A;  4YMN A;  8ICM A;  4RQ6 A;  3RH6 A;  1RZT A;  1JN3 A;  5DB9 A;  5HRE A;  4I2B A;  4PGY A;  4O5K A;  4P2H A;  8ICP A;  4KLD A;  3H37 A;  4FO6 A;  3JPN A;  4PHD A;  4AT7 A;  4X4V A;  4YD2 A;  2BCU A;  3ER8 C;  3AQL A;  4RQ5 A;  5DBB A;  4I2A A;  4I2I A;  1YLQ A;  3HJ1 A;  2B56 A;  1ZJM A;  4RWQ A;  2ZH2 A;  4RQ2 A;  4XA5 A;  2FMS A;  4I2F A;  5DDM A;  4UD4 A;  2HHP A;  5CFT A;  2DRB A;  4X4U A;  8ICB A;  4AT8 B;  1KNY A;  4KLT A;  1UEU A;  5J29 A;  2BE3 A;  4LZG A;  1BPX A;  7ICK A;  4I29 A;  5J0P A;  9ICS A;  5DBC A;  4RQ0 A;  2PBE A;  1XSP A;  5J0Q A;  1MQ2 A;  1F5A A;  4M5D A;  1BPB A;  1MQ3 A;  4PHE A;  4QZA A;  4AT8 A;  4LVS A;  5D63 A;  2ZH1 A;  1TV9 A;  5D4B A;  4R65 A;  3H38 A;  3HX0 A;  7ICT A;  4UAY A;  2P66 A;  4K98 A;  4GXK A;  8ICU A;  3AU6 A;  4LZD A;  3UXN A;  7ICM A;  2I9G A;  4I27 A;  4X4O A;  2NRK A;  2BCS A;  8ICW A;  9ICH A;  2GAF D;  1BPZ A;  3C2M A;  2ISP A;  4IQW A;  4KLG A;  3PMN A;  9ICJ A;  5J0U A;  2PFO A;  1NOM A;  2BBJ A;  4O67 A;  4MF2 A;  2M2T A;  2DR5 A;  4NXX A;  4EBJ A;  4RPX A;  5IIL A;  4XJE A;  1ZQK A;  2BCR A;  1ZQH A;  7ICQ A;  3V7L A;  4YD1 A;  4M9N A;  4WC1 A;  3UXP A;  7ICP A;  3JPP A;  2DR9 A;  4NM2 A;  1OU5 A;  2DVI A;  1ZQF A;  8ICS A;  4O69 A;  3JZ0 A;  4OAI Z;  2ID1 A;  8ICY A;  3WFP A;  4NXU A;  3JPT A;  1ZJN A;  4FHX A;  2FCL A;  1ZQN A;  1VFG A;  4PH5 A;  1Q79 A;  4WC2 A;  2IHM A;  1JMS A;  4I0U A;  4JWN A;  4S3N A;  5DBA A;  4EV6 A;  4LEZ A;  4X5V A;  3LQC B;  2PFQ A;  4O6A A;  4I2H A;  4UB4 A;  4WCW A;  4PGX A;  2M2U A;  2PFP A;  1BPY A;  3WFO A;  3RJI A;  2FMQ A;  2ZH7 A;  4QZH A;  8ICX A;  5DB8 A;  2B4V A;  2IUB A;  2M2W A;  5TZV A;  5HRL A;  3V72 A;  3AUO A;  5B3Q A;  1ZQP A;  2BCV A;  3C66 A;  4JLZ A;  3AQN A;  4IQV A;  4TUR A;  3ISB A;  4PGQ A;  1ZQS A;  4M9H A;  4KLL A;  4M2Y A;  1V4A A;  1ZQM A;  4QZF A;  3RJJ A;  4WBZ A;  5HHH A;  3TFR A;  7ICJ A;  5HRD A;  4NKT A;  4QZG A;  3HWT A;  3HW8 A;  9ICP A;  4DO9 A;  4WC6 A;  4WQL A;  5CP2 A;  4K4H A;  4RT2 A;  3EF2 A;  3C2L A;  5CFU A;  1PX5 A;  3WFQ E;  3UQ2 A;  2GWS A;  1ZQJ A;  8ICT A;  4FH5 A;  3AU2 A;  4KLF A;  4DOC A;  4MFA A;  4KLI A;  1UEV A;  5B3P A;  4K99 A;  1ZQU A;  2ZH5 A;  4UD5 A;  3V7J A;  4KLO A;  8ICN A;  4R66 A;  7ICI A;  4O5E A;  3OWG A;  4PHP A;  8ICG A;  3ER9 B;  5DKW A;  7ICL A;  3JPO A;  1ZQI A;  5J2J A;  5HRG A;  4KLS A;  4KM5 A;  3NKU A;  5HRI A;  8ICF A;  4NY8 A;  2B51 A;  3HJ4 A;  4X0B A;  4NLN A;  3LK9 A;  7ICR A;  8ICO A;  3WFR E;  1KDH A;  4WBY A;  3H3A A; 
#chains in the Genus database with same CATH homology
 4AT9 B;  4XJE A;  4HX0 A;  3OV7 A;  1FA0 A;  4FHV A;  3NYB A;  2DR9 A;  4O68 A;  4KB6 A;  4ATB B;  2DVI A;  4X4P A;  4O69 A;  4OAI Z;  4AT9 A;  4NXU A;  4FHP A;  2EWR A;  1TFY A;  4FHX A;  2FCL A;  1R8B A;  4E7X A;  4X4T A;  1Q79 A;  4K96 A;  2DRA A;  4FH3 A;  4AT7 B;  1TFW A;  4NXT A;  4FHW A;  4ATB A;  4LEZ A;  4O6A A;  4NXW A;  4LEY A;  2ZH4 A;  3OVS A;  1UET A;  4K97 A;  4X4N A;  4X4S A;  1GPJ A;  1R89 A;  2ZH7 A;  2ZHB A;  5D62 A;  2ZH6 A;  2B4V A;  4MKP A;  4OAF A;  3ERC C;  4LT6 A;  4AT7 A;  4X4V A;  5B3Q A;  4K9B A;  3ER8 C;  3OUY B;  4X4Q A;  3C66 A;  4JLZ A;  3HJ1 A;  2B56 A;  3K7D A;  2ZH2 A;  4WQK A;  4K8V A;  4UD4 A;  1R8A A;  2HHP A;  4OAH A;  5CFT A;  2DRB A;  4FHY A;  2DR8 A;  5CHE A;  2ZHA A;  4X4U A;  4NKT A;  4OAG A;  3OUY A;  4AT8 B;  4X4R A;  4NKU A;  4WQL A;  1UEU A;  3OVB A;  4E80 A;  3EF2 A;  5CFU A;  5D61 A;  4FH5 A;  1F5A A;  4M5D A;  4AT8 A;  5D63 A;  2ZH1 A;  1UEV A;  3MCR A;  5B3P A;  4K99 A;  2GA9 D;  2ZH9 A;  2ZH5 A;  4UD5 A;  5CFS A;  4WOY A;  2ZH3 A;  4K9A A;  4K98 A;  2Q66 A;  3PHZ A;  4WH5 A;  1Q78 A;  4LEV A;  1R8C A;  3OWG A;  3ER9 B;  4X4O A;  2IHO A;  3HIY A;  2GAF D;  4KM5 A;  4EP7 A;  3NKU A;  4NXV A;  4LEW A;  2ZH8 A;  2DR7 A;  2O1P A;  4FO1 A;  2B51 A;  3HJ4 A;  4O67 A;  2DR5 A;  4NXX A;  4E8F A;  3OVA A;  4N7R A;  4JLX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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