4O67A

Human cyclic gmp-amp synthase (cgas) in complex with gamp
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
361
structure length
346
Chain Sequence
GASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNTKISAPNEFDVMFKLEVPRIQLEEYSNTRAYYFVKFKRNKENPLSQFLEGEILSASKMLSKFRKIIKEEINDIKDTDVIMKRKRGGSPAVTLLISEKISVDITLALESKSSWPASTQEGLRIQNWLSAKVRKQLRLKPFYLVPKHAEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCRKDCLKLMKYLLEQLKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWDRKDLGLCFDNCVTYFLQCLRTEKLENYFIPEFNLFSSNLIDKRSKEFLTKQIEYERNNEFPVFDE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Cyclic GMP-AMP synthase
total genus 116
structure length 346
sequence length 361
chains with identical sequence B
ec nomenclature ec 2.7.7.86: Cyclic GMP-AMP synthase.
pdb deposition date 2013-12-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03281 Mab-21 Mab-21 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1410.40 Mainly Alpha Orthogonal Bundle Poly(a)-polymerase, middle domain Poly(a)-polymerase, middle domain 4o67A01
3.30.460.90 Alpha Beta 2-Layer Sandwich Beta Polymerase; domain 2 Beta Polymerase; domain 2 4o67A02
4AT8B 4AT8A 4LEWA 4K97A 4JLZA 4NXTA 4AT9B 4OAIZ 4NXVA 4AT9A 4O69A 4KM5A 4MKPA 4KB6A 4OAHA 4O67A 4K98A 4O6AA 4NXUA 4LEVA 4K96A 4AT7A 4LEYA 4NXWA 4WOYA 4OAGA 4ATBB 4ATBA 4K99A 4JLXA 4NXXA 4O68A 4K9AA 4AT7B 4OAFA 4LEZA 4K8VA 4K9BA
chains in the Genus database with same CATH superfamily
4JWMA 4UD4A 4GXJA 3MCRA 4JLZA 4PGYA 1XSPA 4S3NA 4E80A 5J0OA 4X4TA 3RH6A 9ICFA 4HX0A 5J0XA 3PNCA 3C5GA 1MIYA 7ICLA 1R8CA 4WC5A 5J29A 3JPPA 4TUPA 4NLNA 1R89A 5BPCA 4LVSA 3HWTA 5DBBA 3MGIA 1BPBA 2DRBA 4QZGA 1TFYA 3WFQE 3RJKA 4YCXA 3NYBA 2B56A 4NXVA 1VFGA 3UQ0A 4QZEA 2BBHA 4P4MA 7ICMA 3HIYA 7ICRA 2VANA 3JCFA 9ICSA 8ICEA 4RPYA 4UB1A 2ID1A 4Z6CA 2PXIA 4ATBB 1HUZA 4M9HA 4F5RA 3JPQA 3PMLA 9ICIA 4RWOA 2GAFD 5JTGA 4E8FA 9ICBA 3CK6A 2ZH4A 5J0YA 4OAIZ 4NM2A 3AU6A 3NWIA 4EGWA 5J0SA 8ICSA 4TUQA 4K98A 1MIVA 3UPSA 4IQTA 4F5OA 4XQ8A 3TFRA 5IILA 5HHIA 5DB7A 5J0RA 1ZQVA 4UD5A 4RWPA 2DRAA 2BCSA 4XQ7A 3EF2A 4M9LA 4XJEA 4KLEA 3OUYA 8ICVA 4LEZA 4UB4A 4QZHA 3PHZA 4YMOA 5CR0A 2BPFA 8ICLA 2ISOA 4M9JA 4NXTA 4AT9B 8ICIA 4I2DA 4WC1A 3HJ4A 3K7DA 3V7JA 1RPLA 3RJIA 4MF8A 1ZQRA 4I2HA 4KLQA 4EV6A 4FHPA 2W9MA 9ICEA 9ICPA 4YMMA 1R8AA 4EEBA 3RH4A 1ZQUA 5HRHA 4IG8A 1ZQIA 5DDMA 1ZJNA 4I2CA 4KLTA 4PGQA 4FHVA 7ICPA 3AQKA 4X4SA 7ICIA 5J2DA 5BOLA 4DOCA 1YLQA 5J2KA 7ICUA 4K97A 1ZQQA 9ICOA 1HUOA 8ICWA 5BOMA 1ZJMA 3ERCC 8ICTA 4EBJA 4MKPA 4YD2A 4Z6EA 1MQ2A 4RQ1A 1NO5A 9ICXA 5J0WA 4M9GA 3UXPA 1OU5A 5F2VO 3RJEA 2ZH2A 4LT6A 4QZBA 1RZTA 4JLXA 2BPGA 5J0UA 1F5AA 1ZQEA 4QZAA 4UAZA 3LK9A 7ICKA 3C66A 9ICAA 4XUSA 1BPXA 2HN1A 8ICZA 2DR5A 4M5DA 3AQLA 4IQVA 4EBKA 1JMSA 4O5EA 4I2BA 9ICHA 4LZDA 2O1PA 4I27A 5HRFA 3RJGA 3C18A 4WH5A 4FO6A 3V7LA 4FH5A 3V7KA 4KLUA 2EWRA 4I2GA 3HJ1A 2M2TA 5DB6A 2M2VA 4RT2A 3JPTA 1ZQGA 3ISBA 4X4OA 3ER8C 5CP2A 8ICYA 4NLZA 5DB8A 7ICFA 9ICQA 9ICNA 3AUOA 4PPXA 5IIJA 4P2HA 8ICAA 7ICNA 2DVIA 4YMNA 1Q79A 1ZQDA 4KLIA 8ICRA 4O68A 2DR8A 4K4IA 8ICCA 4MFCA 4AT8B 4WC4A 4KLLA 2PFPA 4UBCA 1VJ7A 4R63A 4M0AA 5J2JA 4PH5A 4I29A 4MFAA 7ICSA 2M2WA 2FMPA 4KLJA 4PHPA 3UPQA 4WBZA 8ICBA 5HRDA 3ISDA 4NXUA 2BCQA 3RJJA 5J0TA 4WOYA 5J2GA 9ICGA 3H3AA 4RQ4A 3JPSA 4ATBA 1UEVA 2M2UA 4I2FA 2PFNA 3OUYB 4WC2A 4N7RA 4PHAA 4TURA 3AQMA 2PFQA 3RJFA 8ICFA 4YD1A 5D4BA 3AQNA 1GPJA 4X5VA 4RPZA 3NKUA 5CHGA 5EOZA 4PHDA 4F5QA 2NRKA 2ZH1A 5HR9A 4WC7A 4P4PA 5DECA 4QZIA 4OAHA 2P66A 4I2AA 4MF2A 2IHMA 3UXNA 2PFOA 9ICTA 4RWNA 4LEYA 7ICQA 1V4AA 4OAGA 5J2BA 4MFFA 1BPEA 4FH3A 4PHEA 4NM1A 4QZCA 5HRIA 4M9NA 5J2EA 4AT7A 4K8VA 8ICUA 3JPRA 4F5NA 5DBCA 3B0XA 4X4UA 1TV9A 5IIOA 4RQ7A 5HRGA 1BPYA 5J0PA 9ICMA 4KLOA 4KLSA 2PBEA 2B51A 3OVBA 4I0UA 1MQ3A 2I9GA 8ICPA 3JPNA 2DR9A 4UAYA 1ZQNA 4WQKA 4I2IA 1ZQLA 5D49A 1ZQSA 3WFRE 7ICEA 1ZQJA 4RQ8A 2DR7A 3C5FA 4KLDA 1ZQXA 4NXZA 4RQ0A 4K4GA 4XRHA 4Z6FA 4NY8A 4KB6A 4FHXA 4NKUA 4WQLA 5DEDA 4NLKA 4F5PA 3H37A 4M47A 2ZH6A 2IUBA 4WC0A 5J2HA 4I28A 9ICWA 2Q66A 4O9MA 4NXXA 4K9AA 4UB5A 4OAFA 1ZQYA 8ICOA 2ISPA 5IIMA 1ZQKA 5HRLA 3RH5A 3OV7A 4X4NA 2BBJA 2ZHBA 3HX0A 4QZ8A 2ZH9A 4X0BA 2IHOA 4WC3A 4NKTA 4RQ6A 4JWNA 4K4HA 4I2EA 4PGXA 1WOTA 4I2JA 4GXIA 4LEVA 2B4VA 3C2KA 2BCVA 2O5AA 5B3PA 2HHPA 4KLFA 4M04A 3OGUA 1ZQCA 7ICVA 1KDHA 1Q78A 5DBAA 1R8BA 4RPXA 4EEDA 5IINA 2GWSA 5J0QA 1ZQTA 1ZQFA 3RJHA 5CJ7A 3UXOA 4DOBA 3HW8A 1TFWA 5CHEA 9ICLA 4X4PA 3OWGA 4IQWA 1KNYA 8ICHA 2ZH8A 5DDYA 3TFSA 5HC9A 7ICHA 9ICUA 4O69A 3AU2A 2ZH7A 4UBBA 3H38A 5J2AA 9ICRA 4UB2A 1PX5A 5D46A 3H39A 8ICXA 5J2CA 3ISCA 4M2YA 4LZGA 4X4QA 1XSLA 7ICGA 4EP7A 4AT8A 1JN3A 5CFSA 3C2LA 4KLHA 4P4OA 9ICKA 8ICQA 2FCLA 5J2IA 3MBYA 4KLMA 4RT3A 8ICGA 4E7XA 4O5CA 3MDAA 1ZQWA 2BPCA 1BPDA 4O67A 1MIWA 5D62A 2ZHAA 2BE3A 5HHHA 2ZH5A 1JAJA 4RWQA 8ICKA 5HRKA 9ICJA 1FA0A 4FO1A 4O5KA 1ZQBA 2GA9D 5D61A 5CFTA 1ZQPA 4AT7B 1NOMA 3JZ0A 5TZVA 2BCRA 3JYYA 4R64A 3WFSC 4FHWA 4LEWA 4WBYA 5CA7A 5IIIA 5IIKA 4WC6A 4R66A 3MGHA 3LQCB 5CWRA 4AT9A 3WFPA 4Z6DA 4TUSA 3B0YA 3V72A 1XSNA 1TVAA 4YN4A 1ZQHA 7ICTA 1KEJA 5DKWA 2FMSA 4XA5A 5B3QA 5DB9A 4O6AA 4QZFA 4K96A 4UB3A 3WFOA 7ICJA 2BCUA 4NXWA 4RQ2A 1ZQMA 4X4RA 3GDXA 4QZDA 3ER9B 4X0AA 4IQUA 4QZ9A 8ICJA 1ZQOA 5CFUA 3MDCA 5HRBA 3PMNA 1BPZA 4DOAA 8ICMA 2FMQA 3OVAA 3NVOA 1ZQZA 3C2MA 4KM5A 4GXKA 3K75D 4WCWA 8ICNA 3OVSA 4RQ3A 5D63A 7ICOA 4KLGA 4FHYA 1ZQAA 2HN2A 3L9DA 1JQRA 4DO9A 4UAWA 3JPOA 4R65A 9ICCA 5HREA 2RFFA 5CB1A 2ZH3A 4RQ5A 9ICVA 4K99A 4X4VA 3UQ2A 1UETA 1UEUA 5J2FA 4K9BA
chains in the Genus database with same CATH topology
4UD4A 4K97A 3MCRA 1TFWA 4JLZA 5CHEA 1GPJA 4X4PA 3OWGA 4E80A 3ERCC 3NKUA 2ZH8A 4O69A 4X4TA 2ZH1A 4MKPA 4OAHA 2ZH7A 4HX0A 1R8CA 4LEYA 1R89A 2ZH2A 4LT6A 4OAGA 4JLXA 4FH3A 4X4QA 1F5AA 4AT7A 4K8VA 2DRBA 1TFYA 4EP7A 4AT8A 3C66A 5CFSA 4X4UA 2FCLA 3NYBA 2DR5A 2B56A 4NXVA 4M5DA 4E7XA 2B51A 3OVBA 4O67A 5D62A 2ZHAA 3HIYA 2ZH5A 2DR9A 1FA0A 4FO1A 2O1PA 2GA9D 4ATBB 5D61A 5CFTA 4WH5A 4WQKA 4AT7B 4FH5A 2EWRA 4FHWA 3HJ1A 2GAFD 4LEWA 2DR7A 4E8FA 2ZH4A 4OAIZ 4X4OA 3ER8C 4AT9A 4KB6A 4FHXA 4NKUA 4WQLA 5B3QA 4K98A 4O6AA 4K96A 2ZH6A 4NXWA 2DVIA 1Q79A 4X4RA 2Q66A 4UD5A 2DRAA 4NXXA 4O68A 2DR8A 3EF2A 4K9AA 4XJEA 3ER9B 4OAFA 3OUYA 4LEZA 4AT8B 5CFUA 3OV7A 4X4NA 3PHZA 2ZHBA 4NXTA 4AT9B 2ZH9A 2IHOA 3OVAA 4NKTA 3HJ4A 3K7DA 4KM5A 4FHPA 1R8AA 3OVSA 4NXUA 4LEVA 5D63A 2B4VA 4FHYA 5B3PA 2HHPA 4WOYA 4FHVA 2ZH3A 4ATBA 1UEVA 4K99A 1Q78A 1R8BA 4X4SA 3OUYB 4X4VA 1UETA 4N7RA 1UEUA 4K9BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AT8 B;  4AT8 A;  4LEW A;  4K97 A;  4JLZ A;  4NXT A;  4AT9 B;  4OAI Z;  4NXV A;  4AT9 A;  4O69 A;  4KM5 A;  4MKP A;  4KB6 A;  4OAH A;  4O67 A;  4K98 A;  4O6A A;  4NXU A;  4LEV A;  4K96 A;  4AT7 A;  4LEY A;  4NXW A;  4WOY A;  4OAG A;  4ATB B;  4ATB A;  4K99 A;  4JLX A;  4NXX A;  4O68 A;  4K9A A;  4AT7 B;  4OAF A;  4LEZ A;  4K8V A;  4K9B A; 
#chains in the Genus database with same CATH topology
 4JWM A;  4UD4 A;  4GXJ A;  3MCR A;  4JLZ A;  4PGY A;  1XSP A;  4S3N A;  4E80 A;  5J0O A;  4X4T A;  3RH6 A;  9ICF A;  4HX0 A;  5J0X A;  3PNC A;  3C5G A;  1MIY A;  7ICL A;  1R8C A;  4WC5 A;  5J29 A;  3JPP A;  4TUP A;  4NLN A;  1R89 A;  5BPC A;  4LVS A;  3HWT A;  5DBB A;  3MGI A;  1BPB A;  2DRB A;  4QZG A;  1TFY A;  3WFQ E;  3RJK A;  4YCX A;  3NYB A;  2B56 A;  4NXV A;  1VFG A;  3UQ0 A;  4QZE A;  2BBH A;  4P4M A;  7ICM A;  3HIY A;  7ICR A;  2VAN A;  3JCF A;  9ICS A;  8ICE A;  4RPY A;  4UB1 A;  2ID1 A;  4Z6C A;  2PXI A;  4ATB B;  1HUZ A;  4M9H A;  4F5R A;  3JPQ A;  3PML A;  9ICI A;  4RWO A;  2GAF D;  5JTG A;  4E8F A;  9ICB A;  3CK6 A;  2ZH4 A;  5J0Y A;  4OAI Z;  4NM2 A;  3AU6 A;  3NWI A;  4EGW A;  5J0S A;  8ICS A;  4TUQ A;  4K98 A;  1MIV A;  3UPS A;  4IQT A;  4F5O A;  4XQ8 A;  3TFR A;  5IIL A;  5HHI A;  5DB7 A;  5J0R A;  1ZQV A;  4UD5 A;  4RWP A;  2DRA A;  2BCS A;  4XQ7 A;  3EF2 A;  4M9L A;  4XJE A;  4KLE A;  3OUY A;  8ICV A;  4LEZ A;  4UB4 A;  4QZH A;  3PHZ A;  4YMO A;  5CR0 A;  2BPF A;  8ICL A;  2ISO A;  4M9J A;  4NXT A;  4AT9 B;  8ICI A;  4I2D A;  4WC1 A;  3HJ4 A;  3K7D A;  3V7J A;  1RPL A;  3RJI A;  4MF8 A;  1ZQR A;  4I2H A;  4KLQ A;  4EV6 A;  4FHP A;  2W9M A;  9ICE A;  9ICP A;  4YMM A;  1R8A A;  4EEB A;  3RH4 A;  1ZQU A;  5HRH A;  4IG8 A;  1ZQI A;  5DDM A;  1ZJN A;  4I2C A;  4KLT A;  4PGQ A;  4FHV A;  7ICP A;  3AQK A;  4X4S A;  7ICI A;  5J2D A;  5BOL A;  4DOC A;  1YLQ A;  5J2K A;  7ICU A;  4K97 A;  1ZQQ A;  9ICO A;  1HUO A;  8ICW A;  5BOM A;  1ZJM A;  3ERC C;  8ICT A;  4EBJ A;  4MKP A;  4YD2 A;  4Z6E A;  1MQ2 A;  4RQ1 A;  1NO5 A;  9ICX A;  5J0W A;  4M9G A;  3UXP A;  1OU5 A;  5F2V O;  3RJE A;  2ZH2 A;  4LT6 A;  4QZB A;  1RZT A;  4JLX A;  2BPG A;  5J0U A;  1F5A A;  1ZQE A;  4QZA A;  4UAZ A;  3LK9 A;  7ICK A;  3C66 A;  9ICA A;  4XUS A;  1BPX A;  2HN1 A;  8ICZ A;  2DR5 A;  4M5D A;  3AQL A;  4IQV A;  4EBK A;  1JMS A;  4O5E A;  4I2B A;  9ICH A;  4LZD A;  2O1P A;  4I27 A;  5HRF A;  3RJG A;  3C18 A;  4WH5 A;  4FO6 A;  3V7L A;  4FH5 A;  3V7K A;  4KLU A;  2EWR A;  4I2G A;  3HJ1 A;  2M2T A;  5DB6 A;  2M2V A;  4RT2 A;  3JPT A;  1ZQG A;  3ISB A;  4X4O A;  3ER8 C;  5CP2 A;  8ICY A;  4NLZ A;  5DB8 A;  7ICF A;  9ICQ A;  9ICN A;  3AUO A;  4PPX A;  5IIJ A;  4P2H A;  8ICA A;  7ICN A;  2DVI A;  4YMN A;  1Q79 A;  1ZQD A;  4KLI A;  8ICR A;  4O68 A;  2DR8 A;  4K4I A;  8ICC A;  4MFC A;  4AT8 B;  4WC4 A;  4KLL A;  2PFP A;  4UBC A;  1VJ7 A;  4R63 A;  4M0A A;  5J2J A;  4PH5 A;  4I29 A;  4MFA A;  7ICS A;  2M2W A;  2FMP A;  4KLJ A;  4PHP A;  3UPQ A;  4WBZ A;  8ICB A;  5HRD A;  3ISD A;  4NXU A;  2BCQ A;  3RJJ A;  5J0T A;  4WOY A;  5J2G A;  9ICG A;  3H3A A;  4RQ4 A;  3JPS A;  4ATB A;  1UEV A;  2M2U A;  4I2F A;  2PFN A;  3OUY B;  4WC2 A;  4N7R A;  4PHA A;  4TUR A;  3AQM A;  2PFQ A;  3RJF A;  8ICF A;  4YD1 A;  5D4B A;  3AQN A;  1GPJ A;  4X5V A;  4RPZ A;  3NKU A;  5CHG A;  5EOZ A;  4PHD A;  4F5Q A;  2NRK A;  2ZH1 A;  5HR9 A;  4WC7 A;  4P4P A;  5DEC A;  4QZI A;  4OAH A;  2P66 A;  4I2A A;  4MF2 A;  2IHM A;  3UXN A;  2PFO A;  9ICT A;  4RWN A;  4LEY A;  7ICQ A;  1V4A A;  4OAG A;  5J2B A;  4MFF A;  1BPE A;  4FH3 A;  4PHE A;  4NM1 A;  4QZC A;  5HRI A;  4M9N A;  5J2E A;  4AT7 A;  4K8V A;  8ICU A;  3JPR A;  4F5N A;  5DBC A;  3B0X A;  4X4U A;  1TV9 A;  5IIO A;  4RQ7 A;  5HRG A;  1BPY A;  5J0P A;  9ICM A;  4KLO A;  4KLS A;  2PBE A;  2B51 A;  3OVB A;  4I0U A;  1MQ3 A;  2I9G A;  8ICP A;  3JPN A;  2DR9 A;  4UAY A;  1ZQN A;  4WQK A;  4I2I A;  1ZQL A;  5D49 A;  1ZQS A;  3WFR E;  7ICE A;  1ZQJ A;  4RQ8 A;  2DR7 A;  3C5F A;  4KLD A;  1ZQX A;  4NXZ A;  4RQ0 A;  4K4G A;  4XRH A;  4Z6F A;  4NY8 A;  4KB6 A;  4FHX A;  4NKU A;  4WQL A;  5DED A;  4NLK A;  4F5P A;  3H37 A;  4M47 A;  2ZH6 A;  2IUB A;  4WC0 A;  5J2H A;  4I28 A;  9ICW A;  2Q66 A;  4O9M A;  4NXX A;  4K9A A;  4UB5 A;  4OAF A;  1ZQY A;  8ICO A;  2ISP A;  5IIM A;  1ZQK A;  5HRL A;  3RH5 A;  3OV7 A;  4X4N A;  2BBJ A;  2ZHB A;  3HX0 A;  4QZ8 A;  2ZH9 A;  4X0B A;  2IHO A;  4WC3 A;  4NKT A;  4RQ6 A;  4JWN A;  4K4H A;  4I2E A;  4PGX A;  1WOT A;  4I2J A;  4GXI A;  4LEV A;  2B4V A;  3C2K A;  2BCV A;  2O5A A;  5B3P A;  2HHP A;  4KLF A;  4M04 A;  3OGU A;  1ZQC A;  7ICV A;  1KDH A;  1Q78 A;  5DBA A;  1R8B A;  4RPX A;  4EED A;  5IIN A;  2GWS A;  5J0Q A;  1ZQT A;  1ZQF A;  3RJH A;  5CJ7 A;  3UXO A;  4DOB A;  3HW8 A;  1TFW A;  5CHE A;  9ICL A;  4X4P A;  3OWG A;  4IQW A;  1KNY A;  8ICH A;  2ZH8 A;  5DDY A;  3TFS A;  5HC9 A;  7ICH A;  9ICU A;  4O69 A;  3AU2 A;  2ZH7 A;  4UBB A;  3H38 A;  5J2A A;  9ICR A;  4UB2 A;  1PX5 A;  5D46 A;  3H39 A;  8ICX A;  5J2C A;  3ISC A;  4M2Y A;  4LZG A;  4X4Q A;  1XSL A;  7ICG A;  4EP7 A;  4AT8 A;  1JN3 A;  5CFS A;  3C2L A;  4KLH A;  4P4O A;  9ICK A;  8ICQ A;  2FCL A;  5J2I A;  3MBY A;  4KLM A;  4RT3 A;  8ICG A;  4E7X A;  4O5C A;  3MDA A;  1ZQW A;  2BPC A;  1BPD A;  4O67 A;  1MIW A;  5D62 A;  2ZHA A;  2BE3 A;  5HHH A;  2ZH5 A;  1JAJ A;  4RWQ A;  8ICK A;  5HRK A;  9ICJ A;  1FA0 A;  4FO1 A;  4O5K A;  1ZQB A;  2GA9 D;  5D61 A;  5CFT A;  1ZQP A;  4AT7 B;  1NOM A;  3JZ0 A;  5TZV A;  2BCR A;  3JYY A;  4R64 A;  3WFS C;  4FHW A;  4LEW A;  4WBY A;  5CA7 A;  5III A;  5IIK A;  4WC6 A;  4R66 A;  3MGH A;  3LQC B;  5CWR A;  4AT9 A;  3WFP A;  4Z6D A;  4TUS A;  3B0Y A;  3V72 A;  1XSN A;  1TVA A;  4YN4 A;  1ZQH A;  7ICT A;  1KEJ A;  5DKW A;  2FMS A;  4XA5 A;  5B3Q A;  5DB9 A;  4O6A A;  4QZF A;  4K96 A;  4UB3 A;  3WFO A;  7ICJ A;  2BCU A;  4NXW A;  4RQ2 A;  1ZQM A;  4X4R A;  3GDX A;  4QZD A;  3ER9 B;  4X0A A;  4IQU A;  4QZ9 A;  8ICJ A;  1ZQO A;  5CFU A;  3MDC A;  5HRB A;  3PMN A;  1BPZ A;  4DOA A;  8ICM A;  2FMQ A;  3OVA A;  3NVO A;  1ZQZ A;  3C2M A;  4KM5 A;  4GXK A;  3K75 D;  4WCW A;  8ICN A;  3OVS A;  4RQ3 A;  5D63 A;  7ICO A;  4KLG A;  4FHY A;  1ZQA A;  2HN2 A;  3L9D A;  1JQR A;  4DO9 A;  4UAW A;  3JPO A;  4R65 A;  9ICC A;  5HRE A;  2RFF A;  5CB1 A;  2ZH3 A;  4RQ5 A;  9ICV A;  4K99 A;  4X4V A;  3UQ2 A;  1UET A;  1UEU A;  5J2F A;  4K9B A; 
#chains in the Genus database with same CATH homology
 4UD4 A;  4K97 A;  3MCR A;  1TFW A;  4JLZ A;  5CHE A;  1GPJ A;  4X4P A;  3OWG A;  4E80 A;  3ERC C;  3NKU A;  2ZH8 A;  4O69 A;  4X4T A;  2ZH1 A;  4MKP A;  4OAH A;  2ZH7 A;  4HX0 A;  1R8C A;  4LEY A;  1R89 A;  2ZH2 A;  4LT6 A;  4OAG A;  4JLX A;  4FH3 A;  4X4Q A;  1F5A A;  4AT7 A;  4K8V A;  2DRB A;  1TFY A;  4EP7 A;  4AT8 A;  3C66 A;  5CFS A;  4X4U A;  2FCL A;  3NYB A;  2DR5 A;  2B56 A;  4NXV A;  4M5D A;  4E7X A;  2B51 A;  3OVB A;  4O67 A;  5D62 A;  2ZHA A;  3HIY A;  2ZH5 A;  2DR9 A;  1FA0 A;  4FO1 A;  2O1P A;  2GA9 D;  4ATB B;  5D61 A;  5CFT A;  4WH5 A;  4WQK A;  4AT7 B;  4FH5 A;  2EWR A;  4FHW A;  3HJ1 A;  2GAF D;  4LEW A;  2DR7 A;  4E8F A;  2ZH4 A;  4OAI Z;  4X4O A;  3ER8 C;  4AT9 A;  4KB6 A;  4FHX A;  4NKU A;  4WQL A;  5B3Q A;  4K98 A;  4O6A A;  4K96 A;  2ZH6 A;  4NXW A;  2DVI A;  1Q79 A;  4X4R A;  2Q66 A;  4UD5 A;  2DRA A;  4NXX A;  4O68 A;  2DR8 A;  3EF2 A;  4K9A A;  4XJE A;  3ER9 B;  4OAF A;  3OUY A;  4LEZ A;  4AT8 B;  5CFU A;  3OV7 A;  4X4N A;  3PHZ A;  2ZHB A;  4NXT A;  4AT9 B;  2ZH9 A;  2IHO A;  3OVA A;  4NKT A;  3HJ4 A;  3K7D A;  4KM5 A;  4FHP A;  1R8A A;  3OVS A;  4NXU A;  4LEV A;  5D63 A;  2B4V A;  4FHY A;  5B3P A;  2HHP A;  4WOY A;  4FHV A;  2ZH3 A;  4ATB A;  1UEV A;  4K99 A;  1Q78 A;  1R8B A;  4X4S A;  3OUY B;  4X4V A;  1UET A;  4N7R A;  1UEU A;  4K9B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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