4O68A

Structure of human cyclic gmp-amp synthase (cgas)
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
358
structure length
353
Chain Sequence
ASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNTGSYYEHVKISAPNEFDVMFKLEVPRIQLEEYSNTRAYYFVKFENPLSQFLEGEILSASKMLSKFRKIIKEEINDIKDTDVIMKRKRGGSPAVTLLISEKISVDITLALESKSSWPASTQEGLRIQNWLSAKVRKQLRLKPFYLVPKHAKEGNGFQEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCRKDCLKLMKYLLEQLKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWDRKDLGLCFDNCVTYFLQCLRTEKLENYFIPEFNLFSSNLIDKRSKEFLTKQIEYERNNEFPVF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Cyclic GMP-AMP synthase
total genus 114
structure length 353
sequence length 358
ec nomenclature ec 2.7.7.86: Cyclic GMP-AMP synthase.
pdb deposition date 2013-12-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03281 Mab-21 Mab-21 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1410.40 Mainly Alpha Orthogonal Bundle Poly(a)-polymerase, middle domain Poly(a)-polymerase, middle domain 4o68A01
3.30.460.90 Alpha Beta 2-Layer Sandwich Beta Polymerase; domain 2 Beta Polymerase; domain 2 4o68A02
4JLZA 4NXXA 4AT7A 4OAFA 4K99A 4ATBA 4LEZA 4K9BA 4NXVA 4LEVA 4AT8B 4MKPA 4LEYA 4AT9A 4NXWA 4AT7B 4O68A 4WOYA 4ATBB 4OAIZ 4KM5A 4K96A 4O67A 4NXUA 4OAGA 4OAHA 4K8VA 4O6AA 4KB6A 4O69A 4AT9B 4LEWA 4K9AA 4K97A 4NXTA 4AT8A 4JLXA 4K98A
chains in the Genus database with same CATH superfamily
2BPFA 2ZH2A 4EGWA 5J2IA 5CHGA 2ISPA 1RZTA 5J2JA 3AU6A 4M9HA 4UD5A 3C66A 5CFTA 8ICIA 5J2FA 2BPCA 1ZQAA 3JZ0A 2PFPA 2ZH8A 3MDAA 3AUOA 4IQTA 5DBCA 8ICMA 2HN1A 5J2AA 3H38A 4DOBA 4RWPA 1MIVA 7ICQA 4MF2A 4K4GA 4O5CA 9ICHA 1ZQVA 4XQ8A 5IINA 4XQ7A 3JPQA 4M2YA 5CHEA 2BCUA 1F5AA 4KLFA 7ICRA 5IIMA 1JN3A 4KLTA 1ZQYA 3OGUA 9ICUA 4O9MA 3AU2A 9ICAA 4F5NA 4O5KA 4EBJA 1ZQZA 4E7XA 3K75D 2PFNA 5HC9A 5B3PA 4KLUA 2BCRA 1ZQCA 4Z6EA 4WBYA 4RPYA 4FO6A 4OAFA 5D49A 4KLIA 5HRLA 3NWIA 4AT8B 4WC4A 5DB8A 1NO5A 3JPSA 4FHVA 3HW8A 3UXNA 4FHXA 1ZJNA 4O68A 3L9DA 4KLEA 4DO9A 1R8AA 3MGIA 4UB2A 4FHWA 5IIJA 1ZQPA 2HN2A 3JPNA 3ISDA 2BCSA 1R8BA 5J29A 4RPXA 8ICKA 4JLXA 3C2LA 3NVOA 2ZH5A 1ZQUA 9ICOA 2ZH1A 1HUOA 2GA9D 5IIOA 1ZQJA 1ZQFA 2IHMA 1JQRA 4I27A 3UXPA 3TFSA 2I9GA 5BOMA 1HUZA 2ZH6A 3EF2A 2P66A 4GXKA 4AT7B 4K96A 3MDCA 4I2IA 4OAHA 9ICQA 4O69A 4RT2A 4FH3A 4NKTA 8ICEA 9ICBA 8ICXA 2BE3A 1YLQA 3ER9B 2B51A 4WC1A 5D63A 4MFAA 4YD2A 1MIWA 4PHDA 8ICZA 4JLZA 3K7DA 7ICJA 1JAJA 8ICGA 4M9LA 5CJ7A 3RJFA 5HRIA 5HRGA 2M2TA 5J2KA 1BPZA 3C5FA 4QZHA 3AQLA 2DR5A 4I28A 1ZQIA 5IIKA 4O67A 9ICFA 7ICVA 1TFWA 4QZCA 4FO1A 8ICOA 4RWNA 3V7KA 5DBAA 4GXIA 7ICEA 2M2WA 5CFSA 2B56A 5DKWA 4YD1A 1XSLA 3C5GA 4I2HA 1ZQDA 5IILA 1TFYA 8ICWA 4UAYA 1KEJA 1ZQXA 2W9MA 3H3AA 3NYBA 4WC0A 3H37A 3WFQE 4F5RA 4M5DA 3RJHA 3HJ1A 4WOYA 1ZQHA 1MIYA 4KLDA 4QZEA 9ICIA 4RQ0A 4RWOA 3HX0A 4QZBA 4TUPA 5D62A 4AT8A 2PFQA 3H39A 4EEDA 1BPDA 4P4OA 5DBBA 3JPOA 2RFFA 8ICJA 2O5AA 4P4MA 5J0QA 2ZHBA 4LEZA 1GPJA 4QZIA 4WC3A 1ZQKA 4LEVA 4LT6A 4MKPA 2EWRA 3V7JA 4MFFA 2VANA 9ICJA 8ICVA 3RH5A 7ICUA 1TV9A 2BCQA 8ICAA 3OVBA 3PMLA 7ICHA 4I29A 4YCXA 4K9AA 4RQ2A 8ICCA 9ICGA 7ICSA 4K97A 4I2DA 4FH5A 3HJ4A 4X4PA 3RH6A 5J2EA 3WFOA 4XUSA 4AT7A 5HRHA 3RJIA 4X5VA 4NM1A 3OV7A 9ICVA 1VJ7A 4XJEA 4IQUA 4YMMA 4O5EA 4R64A 4RQ5A 8ICTA 2PBEA 5J0WA 3AQMA 2BPGA 4X4NA 4X4VA 7ICFA 2PFOA 4R66A 3RJJA 1R89A 4UD4A 4FHPA 4M04A 5J0PA 4K98A 1ZJMA 5CA7A 3JYYA 4WQKA 3WFRE 4FHYA 5DB7A 3UPSA 4UAZA 1UEVA 4F5PA 4WBZA 4YMNA 5BOLA 3WFSC 3UXOA 4R63A 8ICUA 4S3NA 3OUYA 2GWSA 3RJEA 3RJGA 7ICKA 5D4BA 5HRFA 2DR8A 4ATBB 4OAIZ 3LQCB 1BPBA 5CR0A 4AT9B 4X0AA 4M9JA 4PGYA 4NXZA 4NM2A 4F5OA 3GDXA 1ZQEA 9ICPA 4NXTA 7ICLA 5HRKA 4UB1A 1UETA 4KLOA 4PPXA 4WCWA 1ZQOA 2ID1A 3MGHA 4RQ4A 9ICNA 5J0UA 3HIYA 2M2UA 3WFPA 1ZQMA 3ERCC 8ICLA 4IG8A 1ZQQA 3OWGA 4NY8A 1BPEA 4WQLA 5HR9A 7ICNA 1BPYA 9ICEA 4X4OA 2IHOA 2FCLA 4R65A 4JWNA 4O6AA 3JPRA 9ICCA 4RWQA 2FMSA 3PMNA 4KLQA 4LZGA 4TUQA 8ICBA 4KLLA 4I2GA 5J0OA 4Z6DA 4MF8A 4M0AA 5EOZA 8ICHA 4PH5A 5DB9A 4PGQA 3HWTA 1R8CA 4RQ1A 1JMSA 3B0YA 4DOAA 8ICRA 4E8FA 2DRBA 2NRKA 7ICPA 5J0SA 4I2EA 5D46A 2HHPA 1BPXA 4KLJA 4EP7A 3ISCA 2Q66A 4UBCA 8ICYA 5DEDA 5CB1A 8ICQA 2ZH4A 4K4HA 4X4TA 4P2HA 4WC6A 1MQ3A 4NXXA 4IQVA 3JPTA 4LZDA 4QZFA 4WC5A 4NXVA 4I2JA 3PNCA 4UBBA 1WOTA 9ICXA 4KLSA 4KLHA 3B0XA 4KM5A 2ZH7A 4NXUA 5CWRA 4WC7A 4QZAA 3AQNA 5HREA 2O1PA 2ZH3A 1ZQRA 4DOCA 4XRHA 3OVSA 4JWMA 5HRBA 4KLGA 4HX0A 4RQ7A 4UAWA 3LK9A 1V4AA 3ISBA 4TUSA 9ICSA 3V7LA 1MQ2A 1ZQWA 2BBJA 4UB3A 4ATBA 1VFGA 1ZQNA 4K9BA 2DR9A 4X4SA 4X4QA 4PGXA 4AT9A 4M9NA 4RQ3A 2ISOA 2ZHAA 5DDYA 2DVIA 9ICRA 4OAGA 4X0BA 4KB6A 4I2CA 1KNYA 5J2BA 9ICWA 9ICMA 4TURA 3RH4A 3C2KA 5HHIA 9ICTA 4I2BA 4PHAA 4QZGA 5B3QA 2IUBA 1XSPA 7ICIA 5J0XA 4K4IA 3MBYA 8ICNA 9ICKA 4IQWA 4RPZA 5IIIA 4NKUA 3UQ2A 1TVAA 5HRDA 3V72A 4QZDA 4WH5A 4NXWA 3AQKA 4P4PA 1UEUA 4I2AA 4EBKA 4UB4A 4GXJA 2BCVA 9ICLA 7ICOA 5J2GA 2GAFD 4UB5A 1RPLA 4LEWA 1XSNA 5D61A 8ICPA 1PX5A 8ICSA 7ICGA 4M47A 8ICFA 3ER8C 4WC2A 4LVSA 2DRAA 1Q79A 3JPPA 3OVAA 4NLKA 4N7RA 4K99A 4RT3A 5J2HA 4EV6A 3UQ0A 4NLNA 4I2FA 7ICMA 1ZQSA 4LEYA 4NLZA 5CFUA 5JTGA 4X4RA 3TFRA 3RJKA 5DECA 4QZ9A 2DR7A 2ZH9A 1OU5A 1NOMA 4F5QA 4M9GA 4MFCA 5TZVA 5BPCA 4YN4A 4X4UA 3NKUA 3PHZA 2BBHA 4YMOA 5CP2A 4RQ6A 1ZQBA 3CK6A 5F2VO 1ZQGA 5J2DA 4Z6FA 5J0TA 4RQ8A 4I0UA 1ZQLA 5J0RA 1Q78A 2B4VA 7ICTA 3C18A 4EEBA 5J0YA 5J2CA 1KDHA 2FMPA 4PHPA 4QZ8A 4Z6CA 4E80A 4K8VA 3UPQA 4KLMA 2M2VA 3OUYB 3C2MA 3MCRA 4XA5A 2FMQA 1FA0A 2PXIA 3JCFA 5HHHA 5DB6A 1ZQTA 5DDMA 4PHEA
chains in the Genus database with same CATH topology
2ZH2A 4JLZA 3K7DA 4HX0A 4WQKA 4FHYA 4ATBA 4K9BA 1UEVA 4UD5A 2DR9A 3C66A 4X4SA 4X4QA 5CFTA 4AT9A 3OUYA 2ZHAA 2DR5A 2DR8A 2ZH8A 4ATBB 4OAIZ 4O67A 2DVIA 4OAGA 1TFWA 4KB6A 4FO1A 4AT9B 4NXTA 5CFSA 2B56A 1UETA 5B3QA 5CHEA 1TFYA 4NKUA 1F5AA 3HIYA 3NYBA 3ERCC 4WH5A 4NXWA 4M5DA 3OWGA 1UEUA 4WQLA 3HJ1A 4WOYA 4X4OA 2IHOA 2FCLA 4O6AA 2GAFD 4LEWA 5D61A 4E7XA 5D62A 4AT8A 3ER8C 5B3PA 2DRAA 1Q79A 3OVAA 4N7RA 4OAFA 4K99A 2ZHBA 4LEZA 1GPJA 1R8CA 4LEVA 4AT8B 4LT6A 4MKPA 2EWRA 4LEYA 4E8FA 2DRBA 4FHVA 5CFUA 4FHXA 4X4RA 4O68A 3OVBA 2DR7A 2ZH9A 2HHPA 1R8AA 4EP7A 2Q66A 4FHWA 4X4UA 3NKUA 4K9AA 3PHZA 4K97A 1R8BA 4FH5A 2ZH4A 4JLXA 4X4TA 3HJ4A 4X4PA 2ZH5A 4NXXA 4AT7A 2ZH1A 4NXVA 2GA9D 1Q78A 2B4VA 3OV7A 4XJEA 2ZH6A 3EF2A 4AT7B 4K96A 4KM5A 2ZH7A 4NXUA 4X4NA 4OAHA 4E80A 4K8VA 4X4VA 3OUYB 4O69A 3MCRA 4FH3A 4NKTA 2O1PA 2ZH3A 3ER9B 1FA0A 1R89A 2B51A 5D63A 4UD4A 3OVSA 4FHPA 4K98A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JLZ A;  4NXX A;  4AT7 A;  4OAF A;  4K99 A;  4ATB A;  4LEZ A;  4K9B A;  4NXV A;  4LEV A;  4AT8 B;  4MKP A;  4LEY A;  4AT9 A;  4NXW A;  4AT7 B;  4O68 A;  4WOY A;  4ATB B;  4OAI Z;  4KM5 A;  4K96 A;  4O67 A;  4NXU A;  4OAG A;  4OAH A;  4K8V A;  4O6A A;  4KB6 A;  4O69 A;  4AT9 B;  4LEW A;  4K9A A;  4K97 A;  4NXT A;  4AT8 A;  4JLX A;  4K98 A; 
#chains in the Genus database with same CATH topology
 2BPF A;  2ZH2 A;  4EGW A;  5J2I A;  5CHG A;  2ISP A;  1RZT A;  5J2J A;  3AU6 A;  4M9H A;  4UD5 A;  3C66 A;  5CFT A;  8ICI A;  5J2F A;  2BPC A;  1ZQA A;  3JZ0 A;  2PFP A;  2ZH8 A;  3MDA A;  3AUO A;  4IQT A;  5DBC A;  8ICM A;  2HN1 A;  5J2A A;  3H38 A;  4DOB A;  4RWP A;  1MIV A;  7ICQ A;  4MF2 A;  4K4G A;  4O5C A;  9ICH A;  1ZQV A;  4XQ8 A;  5IIN A;  4XQ7 A;  3JPQ A;  4M2Y A;  5CHE A;  2BCU A;  1F5A A;  4KLF A;  7ICR A;  5IIM A;  1JN3 A;  4KLT A;  1ZQY A;  3OGU A;  9ICU A;  4O9M A;  3AU2 A;  9ICA A;  4F5N A;  4O5K A;  4EBJ A;  1ZQZ A;  4E7X A;  3K75 D;  2PFN A;  5HC9 A;  5B3P A;  4KLU A;  2BCR A;  1ZQC A;  4Z6E A;  4WBY A;  4RPY A;  4FO6 A;  4OAF A;  5D49 A;  4KLI A;  5HRL A;  3NWI A;  4AT8 B;  4WC4 A;  5DB8 A;  1NO5 A;  3JPS A;  4FHV A;  3HW8 A;  3UXN A;  4FHX A;  1ZJN A;  4O68 A;  3L9D A;  4KLE A;  4DO9 A;  1R8A A;  3MGI A;  4UB2 A;  4FHW A;  5IIJ A;  1ZQP A;  2HN2 A;  3JPN A;  3ISD A;  2BCS A;  1R8B A;  5J29 A;  4RPX A;  8ICK A;  4JLX A;  3C2L A;  3NVO A;  2ZH5 A;  1ZQU A;  9ICO A;  2ZH1 A;  1HUO A;  2GA9 D;  5IIO A;  1ZQJ A;  1ZQF A;  2IHM A;  1JQR A;  4I27 A;  3UXP A;  3TFS A;  2I9G A;  5BOM A;  1HUZ A;  2ZH6 A;  3EF2 A;  2P66 A;  4GXK A;  4AT7 B;  4K96 A;  3MDC A;  4I2I A;  4OAH A;  9ICQ A;  4O69 A;  4RT2 A;  4FH3 A;  4NKT A;  8ICE A;  9ICB A;  8ICX A;  2BE3 A;  1YLQ A;  3ER9 B;  2B51 A;  4WC1 A;  5D63 A;  4MFA A;  4YD2 A;  1MIW A;  4PHD A;  8ICZ A;  4JLZ A;  3K7D A;  7ICJ A;  1JAJ A;  8ICG A;  4M9L A;  5CJ7 A;  3RJF A;  5HRI A;  5HRG A;  2M2T A;  5J2K A;  1BPZ A;  3C5F A;  4QZH A;  3AQL A;  2DR5 A;  4I28 A;  1ZQI A;  5IIK A;  4O67 A;  9ICF A;  7ICV A;  1TFW A;  4QZC A;  4FO1 A;  8ICO A;  4RWN A;  3V7K A;  5DBA A;  4GXI A;  7ICE A;  2M2W A;  5CFS A;  2B56 A;  5DKW A;  4YD1 A;  1XSL A;  3C5G A;  4I2H A;  1ZQD A;  5IIL A;  1TFY A;  8ICW A;  4UAY A;  1KEJ A;  1ZQX A;  2W9M A;  3H3A A;  3NYB A;  4WC0 A;  3H37 A;  3WFQ E;  4F5R A;  4M5D A;  3RJH A;  3HJ1 A;  4WOY A;  1ZQH A;  1MIY A;  4KLD A;  4QZE A;  9ICI A;  4RQ0 A;  4RWO A;  3HX0 A;  4QZB A;  4TUP A;  5D62 A;  4AT8 A;  2PFQ A;  3H39 A;  4EED A;  1BPD A;  4P4O A;  5DBB A;  3JPO A;  2RFF A;  8ICJ A;  2O5A A;  4P4M A;  5J0Q A;  2ZHB A;  4LEZ A;  1GPJ A;  4QZI A;  4WC3 A;  1ZQK A;  4LEV A;  4LT6 A;  4MKP A;  2EWR A;  3V7J A;  4MFF A;  2VAN A;  9ICJ A;  8ICV A;  3RH5 A;  7ICU A;  1TV9 A;  2BCQ A;  8ICA A;  3OVB A;  3PML A;  7ICH A;  4I29 A;  4YCX A;  4K9A A;  4RQ2 A;  8ICC A;  9ICG A;  7ICS A;  4K97 A;  4I2D A;  4FH5 A;  3HJ4 A;  4X4P A;  3RH6 A;  5J2E A;  3WFO A;  4XUS A;  4AT7 A;  5HRH A;  3RJI A;  4X5V A;  4NM1 A;  3OV7 A;  9ICV A;  1VJ7 A;  4XJE A;  4IQU A;  4YMM A;  4O5E A;  4R64 A;  4RQ5 A;  8ICT A;  2PBE A;  5J0W A;  3AQM A;  2BPG A;  4X4N A;  4X4V A;  7ICF A;  2PFO A;  4R66 A;  3RJJ A;  1R89 A;  4UD4 A;  4FHP A;  4M04 A;  5J0P A;  4K98 A;  1ZJM A;  5CA7 A;  3JYY A;  4WQK A;  3WFR E;  4FHY A;  5DB7 A;  3UPS A;  4UAZ A;  1UEV A;  4F5P A;  4WBZ A;  4YMN A;  5BOL A;  3WFS C;  3UXO A;  4R63 A;  8ICU A;  4S3N A;  3OUY A;  2GWS A;  3RJE A;  3RJG A;  7ICK A;  5D4B A;  5HRF A;  2DR8 A;  4ATB B;  4OAI Z;  3LQC B;  1BPB A;  5CR0 A;  4AT9 B;  4X0A A;  4M9J A;  4PGY A;  4NXZ A;  4NM2 A;  4F5O A;  3GDX A;  1ZQE A;  9ICP A;  4NXT A;  7ICL A;  5HRK A;  4UB1 A;  1UET A;  4KLO A;  4PPX A;  4WCW A;  1ZQO A;  2ID1 A;  3MGH A;  4RQ4 A;  9ICN A;  5J0U A;  3HIY A;  2M2U A;  3WFP A;  1ZQM A;  3ERC C;  8ICL A;  4IG8 A;  1ZQQ A;  3OWG A;  4NY8 A;  1BPE A;  4WQL A;  5HR9 A;  7ICN A;  1BPY A;  9ICE A;  4X4O A;  2IHO A;  2FCL A;  4R65 A;  4JWN A;  4O6A A;  3JPR A;  9ICC A;  4RWQ A;  2FMS A;  3PMN A;  4KLQ A;  4LZG A;  4TUQ A;  8ICB A;  4KLL A;  4I2G A;  5J0O A;  4Z6D A;  4MF8 A;  4M0A A;  5EOZ A;  8ICH A;  4PH5 A;  5DB9 A;  4PGQ A;  3HWT A;  1R8C A;  4RQ1 A;  1JMS A;  3B0Y A;  4DOA A;  8ICR A;  4E8F A;  2DRB A;  2NRK A;  7ICP A;  5J0S A;  4I2E A;  5D46 A;  2HHP A;  1BPX A;  4KLJ A;  4EP7 A;  3ISC A;  2Q66 A;  4UBC A;  8ICY A;  5DED A;  5CB1 A;  8ICQ A;  2ZH4 A;  4K4H A;  4X4T A;  4P2H A;  4WC6 A;  1MQ3 A;  4NXX A;  4IQV A;  3JPT A;  4LZD A;  4QZF A;  4WC5 A;  4NXV A;  4I2J A;  3PNC A;  4UBB A;  1WOT A;  9ICX A;  4KLS A;  4KLH A;  3B0X A;  4KM5 A;  2ZH7 A;  4NXU A;  5CWR A;  4WC7 A;  4QZA A;  3AQN A;  5HRE A;  2O1P A;  2ZH3 A;  1ZQR A;  4DOC A;  4XRH A;  3OVS A;  4JWM A;  5HRB A;  4KLG A;  4HX0 A;  4RQ7 A;  4UAW A;  3LK9 A;  1V4A A;  3ISB A;  4TUS A;  9ICS A;  3V7L A;  1MQ2 A;  1ZQW A;  2BBJ A;  4UB3 A;  4ATB A;  1VFG A;  1ZQN A;  4K9B A;  2DR9 A;  4X4S A;  4X4Q A;  4PGX A;  4AT9 A;  4M9N A;  4RQ3 A;  2ISO A;  2ZHA A;  5DDY A;  2DVI A;  9ICR A;  4OAG A;  4X0B A;  4KB6 A;  4I2C A;  1KNY A;  5J2B A;  9ICW A;  9ICM A;  4TUR A;  3RH4 A;  3C2K A;  5HHI A;  9ICT A;  4I2B A;  4PHA A;  4QZG A;  5B3Q A;  2IUB A;  1XSP A;  7ICI A;  5J0X A;  4K4I A;  3MBY A;  8ICN A;  9ICK A;  4IQW A;  4RPZ A;  5III A;  4NKU A;  3UQ2 A;  1TVA A;  5HRD A;  3V72 A;  4QZD A;  4WH5 A;  4NXW A;  3AQK A;  4P4P A;  1UEU A;  4I2A A;  4EBK A;  4UB4 A;  4GXJ A;  2BCV A;  9ICL A;  7ICO A;  5J2G A;  2GAF D;  4UB5 A;  1RPL A;  4LEW A;  1XSN A;  5D61 A;  8ICP A;  1PX5 A;  8ICS A;  7ICG A;  4M47 A;  8ICF A;  3ER8 C;  4WC2 A;  4LVS A;  2DRA A;  1Q79 A;  3JPP A;  3OVA A;  4NLK A;  4N7R A;  4K99 A;  4RT3 A;  5J2H A;  4EV6 A;  3UQ0 A;  4NLN A;  4I2F A;  7ICM A;  1ZQS A;  4LEY A;  4NLZ A;  5CFU A;  5JTG A;  4X4R A;  3TFR A;  3RJK A;  5DEC A;  4QZ9 A;  2DR7 A;  2ZH9 A;  1OU5 A;  1NOM A;  4F5Q A;  4M9G A;  4MFC A;  5TZV A;  5BPC A;  4YN4 A;  4X4U A;  3NKU A;  3PHZ A;  2BBH A;  4YMO A;  5CP2 A;  4RQ6 A;  1ZQB A;  3CK6 A;  5F2V O;  1ZQG A;  5J2D A;  4Z6F A;  5J0T A;  4RQ8 A;  4I0U A;  1ZQL A;  5J0R A;  1Q78 A;  2B4V A;  7ICT A;  3C18 A;  4EEB A;  5J0Y A;  5J2C A;  1KDH A;  2FMP A;  4PHP A;  4QZ8 A;  4Z6C A;  4E80 A;  4K8V A;  3UPQ A;  4KLM A;  2M2V A;  3OUY B;  3C2M A;  3MCR A;  4XA5 A;  2FMQ A;  1FA0 A;  2PXI A;  3JCF A;  5HHH A;  5DB6 A;  1ZQT A;  5DDM A;  4PHE A; 
#chains in the Genus database with same CATH homology
 2ZH2 A;  4JLZ A;  3K7D A;  4HX0 A;  4WQK A;  4FHY A;  4ATB A;  4K9B A;  1UEV A;  4UD5 A;  2DR9 A;  3C66 A;  4X4S A;  4X4Q A;  5CFT A;  4AT9 A;  3OUY A;  2ZHA A;  2DR5 A;  2DR8 A;  2ZH8 A;  4ATB B;  4OAI Z;  4O67 A;  2DVI A;  4OAG A;  1TFW A;  4KB6 A;  4FO1 A;  4AT9 B;  4NXT A;  5CFS A;  2B56 A;  1UET A;  5B3Q A;  5CHE A;  1TFY A;  4NKU A;  1F5A A;  3HIY A;  3NYB A;  3ERC C;  4WH5 A;  4NXW A;  4M5D A;  3OWG A;  1UEU A;  4WQL A;  3HJ1 A;  4WOY A;  4X4O A;  2IHO A;  2FCL A;  4O6A A;  2GAF D;  4LEW A;  5D61 A;  4E7X A;  5D62 A;  4AT8 A;  3ER8 C;  5B3P A;  2DRA A;  1Q79 A;  3OVA A;  4N7R A;  4OAF A;  4K99 A;  2ZHB A;  4LEZ A;  1GPJ A;  1R8C A;  4LEV A;  4AT8 B;  4LT6 A;  4MKP A;  2EWR A;  4LEY A;  4E8F A;  2DRB A;  4FHV A;  5CFU A;  4FHX A;  4X4R A;  4O68 A;  3OVB A;  2DR7 A;  2ZH9 A;  2HHP A;  1R8A A;  4EP7 A;  2Q66 A;  4FHW A;  4X4U A;  3NKU A;  4K9A A;  3PHZ A;  4K97 A;  1R8B A;  4FH5 A;  2ZH4 A;  4JLX A;  4X4T A;  3HJ4 A;  4X4P A;  2ZH5 A;  4NXX A;  4AT7 A;  2ZH1 A;  4NXV A;  2GA9 D;  1Q78 A;  2B4V A;  3OV7 A;  4XJE A;  2ZH6 A;  3EF2 A;  4AT7 B;  4K96 A;  4KM5 A;  2ZH7 A;  4NXU A;  4X4N A;  4OAH A;  4E80 A;  4K8V A;  4X4V A;  3OUY B;  4O69 A;  3MCR A;  4FH3 A;  4NKT A;  2O1P A;  2ZH3 A;  3ER9 B;  1FA0 A;  1R89 A;  2B51 A;  5D63 A;  4UD4 A;  3OVS A;  4FHP A;  4K98 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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