4O69A

Human cyclic gmp-amp synthase (cgas) in complex with sulfate ion
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
362
structure length
353
Chain Sequence
MGASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNTGSYYEHVKISAPNEFDVMFKLEVPRIQLEEYSNTRAYYFVKFKRNPKENPLSQFLEGEILSASKMLSKFRKIIKEEINDITDVIMKRKRGPAVTLLISEKISVDITLALESKSSWPASTQEGLRIQNWLSAKVRKQLRLKPFYLVPKHAKQEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCRKDCLKLMKYLLEQLKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWDRKDLGLCFDNCVTYFLQCLRTEKLENYFIPEFNLFSSNLIDKRSKEFLTKQIEYERNNEFPVFDE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
source organism Homo sapiens
publication title The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
pubmed doi rcsb
molecule keywords Cyclic GMP-AMP synthase
total genus 128
structure length 353
sequence length 362
ec nomenclature ec 2.7.7.86: Cyclic GMP-AMP synthase.
pdb deposition date 2013-12-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03281 Mab-21 Mab-21 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1410.40 Mainly Alpha Orthogonal Bundle Poly(a)-polymerase, middle domain Poly(a)-polymerase, middle domain 4o69A01
3.30.460.90 Alpha Beta 2-Layer Sandwich Beta Polymerase; domain 2 Beta Polymerase; domain 2 4o69A02
4NXUA 4AT8B 4KM5A 4O69A 4K96A 4JLXA 4WOYA 4ATBA 4AT7B 4OAIZ 4NXWA 4LEVA 4NXTA 4NXVA 4NXXA 4AT9B 4K9AA 4AT8A 4LEZA 4K98A 4AT7A 4K8VA 4AT9A 4OAFA 4K99A 4LEWA 4OAGA 4MKPA 4JLZA 4O68A 4ATBB 4LEYA 4OAHA 4K9BA 4KB6A 4O67A 4O6AA 4K97A
chains in the Genus database with same CATH superfamily
4YCXA 4X4VA 8ICJA 2EWRA 4O5CA 5J0XA 3JPRA 5HRKA 3CK6A 5CJ7A 2B56A 4QZGA 4WBZA 5D49A 3B0YA 1VFGA 3V72A 5J0TA 1FA0A 3JCFA 1ZQGA 4EEBA 9ICMA 2BCUA 5J2DA 1ZQTA 1R8AA 4WC4A 4OAHA 5J2EA 9ICLA 3PNCA 5DKWA 2PXIA 4I29A 4FO1A 1UEVA 5CP2A 1V4AA 1ZQAA 5CA7A 1TVAA 3ERCC 4WC5A 2ZH1A 3ISCA 3ER8C 4K9AA 4F5PA 8ICQA 2ZH9A 5D61A 4RQ2A 3WFSC 3PMLA 3JPSA 9ICFA 4KLMA 5HRLA 1ZQMA 9ICUA 2HN2A 4M9LA 1NO5A 5J2AA 4WC2A 9ICNA 4UB5A 5B3QA 5HRGA 3JPNA 1RZTA 4KLLA 1HUOA 4NLKA 4ATBB 9ICIA 4PGYA 1ZQJA 4M0AA 3HIYA 4QZ9A 4PHPA 3RH5A 1PX5A 4M2YA 4ATBA 2FCLA 5J0WA 4NXVA 5HRHA 3NKUA 4M5DA 4NXZA 4QZHA 3LK9A 4KLHA 9ICRA 1BPZA 4M9NA 2GA9D 1R8BA 4QZFA 3B0XA 4RQ3A 4NKTA 1JAJA 1RPLA 4EBJA 4X5VA 4MKPA 5CB1A 5J2CA 4RQ0A 5TZVA 5DBCA 5D4BA 5BOMA 9ICXA 4RT3A 3RJFA 2ZH8A 3OGUA 4UD5A 4K4HA 4NXWA 3UQ0A 4P4PA 3NYBA 3C2LA 4M47A 4K4GA 1VJ7A 8ICVA 4I2JA 4NLNA 4RWPA 2PBEA 4M9JA 5DB8A 1MIVA 4KLGA 4KLSA 1KNYA 9ICQA 5JTGA 1ZJNA 4R66A 3AU2A 4XUSA 2BCVA 2ZH7A 4Z6FA 4KB6A 1BPXA 1R8CA 1ZQSA 5HC9A 4FHXA 4EP7A 4WC6A 2IHOA 1JMSA 3OUYA 4R63A 7ICFA 1ZQOA 4DOAA 2P66A 5J2HA 4M9GA 3HJ4A 3TFRA 4RPZA 2M2VA 5J2JA 2FMSA 2M2WA 4GXJA 5J0RA 5HRDA 5DB9A 4KLOA 9ICPA 4LEYA 4FHVA 1ZQUA 4F5QA 4TUQA 7ICUA 3OVBA 4R64A 4KLDA 3H3AA 7ICLA 4WOYA 9ICSA 2ZH3A 4F5RA 3JPTA 4NXXA 4WC0A 4RWOA 3UQ2A 1JN3A 4MFAA 3ISBA 4K98A 1ZQKA 3UPSA 2BPFA 4XA5A 4RWQA 4KLTA 5D63A 4PHAA 3WFRE 2B4VA 2ZH5A 8ICLA 4IQTA 3C2KA 4UBBA 3MCRA 4MFCA 3L9DA 3UXPA 1XSPA 1KDHA 3H38A 1MIWA 3OVSA 4XRHA 5CHEA 4X4PA 8ICOA 1MIYA 2ZH4A 5J0PA 3JPPA 2GAFD 7ICHA 4UAZA 4I2BA 3H37A 3LQCB 7ICQA 9ICOA 2BPCA 5BPCA 4NY8A 3AQMA 4YD2A 8ICSA 9ICGA 9ICVA 4NLZA 7ICRA 2I9GA 3HX0A 8ICBA 2DR9A 5IILA 4QZEA 2ZHAA 4R65A 3AUOA 1R89A 4M9HA 2DRBA 9ICHA 7ICIA 5EOZA 3RH4A 9ICKA 4NXUA 7ICEA 9ICWA 5DB6A 4AT7B 3MGHA 3MDAA 4UAWA 1XSLA 4E80A 4I0UA 4FH5A 2BBHA 4AT7A 3C5FA 4EBKA 7ICGA 1F5AA 1ZQPA 9ICTA 5J0YA 8ICAA 4LT6A 5J2BA 4I2DA 2ISOA 3RH6A 4X0AA 4OAGA 2NRKA 7ICVA 1ZJMA 5CHGA 5J0QA 4K9BA 5J2FA 8ICMA 4KLEA 4O9MA 1HUZA 2HN1A 4RT2A 4RWNA 4MF2A 5D62A 8ICZA 3RJKA 4Z6CA 1MQ2A 5DDMA 4QZBA 7ICPA 4DOCA 1ZQYA 2PFQA 5DB7A 4OAFA 4RPXA 7ICSA 5D46A 3UPQA 5HRBA 3C66A 2DR5A 3MBYA 4O5KA 2O5AA 4I2CA 5IIMA 4KLUA 4O67A 3OUYB 2FMPA 4O6AA 1TV9A 4I2FA 4KLQA 8ICHA 5HREA 5CFSA 4WH5A 4QZAA 1MQ3A 1Q79A 5HHHA 4UB1A 4LEVA 1BPYA 3RJJA 4M04A 4S3NA 1UEUA 4EEDA 1ZQFA 1TFWA 4I28A 4I2IA 5J2IA 2FMQA 1ZQVA 2DRAA 4PGXA 1ZQZA 4WCWA 4P4OA 1ZQQA 4X4SA 2VANA 4JWMA 3V7JA 3NVOA 1Q78A 1ZQLA 5F2VO 4RQ1A 5DDYA 1TFYA 3C18A 5IIOA 4XQ8A 8ICXA 3RJIA 4K96A 4XQ7A 5HRFA 4JLXA 5J2KA 2PFOA 3AQNA 2ZH2A 3C2MA 7ICJA 4LZGA 5CFTA 3WFOA 4QZIA 8ICRA 4P4MA 1ZQNA 4IG8A 3UXNA 4WC1A 4N7RA 4X4NA 4YD1A 4NKUA 3ER9B 8ICKA 8ICIA 2DR7A 4F5NA 4RQ4A 4KLFA 4E8FA 5J0UA 4PHEA 4X0BA 1WOTA 8ICWA 4PPXA 4NM1A 3HW8A 2PFNA 3UXOA 2B51A 2O1PA 5DECA 4WQLA 4UB3A 8ICEA 5CWRA 8ICGA 4AT9B 5J29A 4MF8A 9ICEA 2W9MA 4EV6A 4I2AA 4RQ5A 2PFPA 1UETA 4TUPA 4QZ8A 4AT9A 4F5OA 3K75D 4WBYA 2BCRA 4RQ6A 3AU6A 4YMMA 5DBAA 4O68A 4X4TA 4IQVA 3JYYA 4UB2A 2BPGA 3ISDA 4X4UA 4LZDA 2DVIA 4AT8B 4O69A 3JPOA 4XJEA 4P2HA 1GPJA 2BBJA 7ICOA 4K4IA 4TUSA 2Q66A 4YMNA 4NXTA 4UD4A 2DR8A 4AT8A 2BE3A 4O5EA 4X4OA 1BPEA 5IIIA 1ZQXA 1ZQWA 3H39A 5HRIA 4NM2A 1ZQRA 4I2HA 5HHIA 2HHPA 4DO9A 3WFQE 4JWNA 5HR9A 4K97A 4KM5A 4QZDA 4I27A 4KLIA 4FH3A 4PGQA 3PHZA 5BOLA 3TFSA 4YN4A 2IHMA 4QZCA 3HJ1A 4FHWA 4FO6A 3EF2A 3AQKA 3NWIA 4IQWA 3PMNA 3RJGA 4X4RA 4FHPA 4UBCA 2ZH6A 3AQLA 4JLZA 1ZQCA 8ICYA 1ZQEA 8ICFA 3OV7A 7ICMA 4IQUA 5J0SA 4GXKA 7ICKA 5IIKA 5CR0A 3RJEA 2BCSA 3V7KA 8ICUA 4OAIZ 1YLQA 4RQ8A 1ZQHA 2GWSA 2ID1A 4DOBA 1NOMA 4LEZA 4I2GA 4PHDA 9ICJA 4Z6DA 4UAYA 8ICTA 9ICCA 1BPBA 4K8VA 1BPDA 4FHYA 3C5GA 3OVAA 1JQRA 9ICBA 1ZQIA 2BCQA 4RQ7A 4TURA 4I2EA 4WQKA 3JZ0A 3MDCA 3HWTA 8ICNA 9ICAA 1ZQBA 3V7LA 1KEJA 4MFFA 5IINA 4E7XA 2IUBA 3JPQA 4WC7A 4LVSA 4Z6EA 2M2UA 4YMOA 4X4QA 5CFUA 3OWGA 2ZHBA 3RJHA 4RPYA 7ICNA 1OU5A 5DEDA 7ICTA 4PH5A 3MGIA 1XSNA 4UB4A 3WFPA 5B3PA 4HX0A 4GXIA 4K99A 3GDXA 8ICPA 4LEWA 1ZQDA 4EGWA 4WC3A 4KLJA 5DBBA 5IIJA 3K7DA 2RFFA 5J0OA 2ISPA 2M2TA 5J2GA 8ICCA
chains in the Genus database with same CATH topology
4X4UA 4FHXA 2DVIA 4AT8B 4O69A 4EP7A 4X4VA 4XJEA 2EWRA 1GPJA 2IHOA 3OUYA 2Q66A 4NXTA 4UD4A 3HJ4A 2DR8A 4AT8A 5D62A 2B56A 4X4OA 4OAFA 1FA0A 3C66A 2DR5A 1R8AA 2HHPA 4LEYA 4FHVA 4OAHA 4O67A 3OUYB 3OVBA 4O6AA 4K97A 4FO1A 1UEVA 5CFSA 4WH5A 4KM5A 4WOYA 1Q79A 4FH3A 2ZH3A 3ERCC 4LEVA 4NXXA 2ZH1A 3ER8C 3PHZA 4K9AA 1UEUA 2ZH9A 5D61A 4K98A 1TFWA 3HJ1A 4FHWA 2DRAA 3EF2A 5D63A 4X4SA 2B4VA 2ZH5A 5B3QA 1Q78A 4FHPA 4X4RA 3MCRA 2ZH6A 4JLZA 4ATBB 1TFYA 3OV7A 3HIYA 3OVSA 5CHEA 4X4PA 4K96A 4JLXA 4ATBA 2ZH4A 4OAIZ 2ZH2A 2FCLA 2GAFD 4NXVA 5CFTA 3NKUA 4LEZA 4M5DA 4K8VA 4N7RA 4FHYA 3OVAA 4X4NA 2GA9D 1R8BA 4NKUA 3ER9B 2DR7A 4NKTA 4WQKA 2DR9A 4E8FA 4MKPA 2ZHAA 4E7XA 1R89A 2DRBA 4NXUA 2B51A 2O1PA 4X4QA 2ZH8A 4UD5A 5CFUA 4AT7B 4WQLA 4NXWA 3OWGA 4AT9B 2ZHBA 3NYBA 4E80A 4FH5A 1UETA 4AT7A 4AT9A 1F5AA 5B3PA 4HX0A 4LT6A 4K99A 4LEWA 4OAGA 3K7DA 4O68A 2ZH7A 4X4TA 4KB6A 4K9BA 1R8CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NXU A;  4AT8 B;  4KM5 A;  4O69 A;  4K96 A;  4JLX A;  4WOY A;  4ATB A;  4AT7 B;  4OAI Z;  4NXW A;  4LEV A;  4NXT A;  4NXV A;  4NXX A;  4AT9 B;  4K9A A;  4AT8 A;  4LEZ A;  4K98 A;  4AT7 A;  4K8V A;  4AT9 A;  4OAF A;  4K99 A;  4LEW A;  4OAG A;  4MKP A;  4JLZ A;  4O68 A;  4ATB B;  4LEY A;  4OAH A;  4K9B A;  4KB6 A;  4O67 A;  4O6A A;  4K97 A; 
#chains in the Genus database with same CATH topology
 4YCX A;  4X4V A;  8ICJ A;  2EWR A;  4O5C A;  5J0X A;  3JPR A;  5HRK A;  3CK6 A;  5CJ7 A;  2B56 A;  4QZG A;  4WBZ A;  5D49 A;  3B0Y A;  1VFG A;  3V72 A;  5J0T A;  1FA0 A;  3JCF A;  1ZQG A;  4EEB A;  9ICM A;  2BCU A;  5J2D A;  1ZQT A;  1R8A A;  4WC4 A;  4OAH A;  5J2E A;  9ICL A;  3PNC A;  5DKW A;  2PXI A;  4I29 A;  4FO1 A;  1UEV A;  5CP2 A;  1V4A A;  1ZQA A;  5CA7 A;  1TVA A;  3ERC C;  4WC5 A;  2ZH1 A;  3ISC A;  3ER8 C;  4K9A A;  4F5P A;  8ICQ A;  2ZH9 A;  5D61 A;  4RQ2 A;  3WFS C;  3PML A;  3JPS A;  9ICF A;  4KLM A;  5HRL A;  1ZQM A;  9ICU A;  2HN2 A;  4M9L A;  1NO5 A;  5J2A A;  4WC2 A;  9ICN A;  4UB5 A;  5B3Q A;  5HRG A;  3JPN A;  1RZT A;  4KLL A;  1HUO A;  4NLK A;  4ATB B;  9ICI A;  4PGY A;  1ZQJ A;  4M0A A;  3HIY A;  4QZ9 A;  4PHP A;  3RH5 A;  1PX5 A;  4M2Y A;  4ATB A;  2FCL A;  5J0W A;  4NXV A;  5HRH A;  3NKU A;  4M5D A;  4NXZ A;  4QZH A;  3LK9 A;  4KLH A;  9ICR A;  1BPZ A;  4M9N A;  2GA9 D;  1R8B A;  4QZF A;  3B0X A;  4RQ3 A;  4NKT A;  1JAJ A;  1RPL A;  4EBJ A;  4X5V A;  4MKP A;  5CB1 A;  5J2C A;  4RQ0 A;  5TZV A;  5DBC A;  5D4B A;  5BOM A;  9ICX A;  4RT3 A;  3RJF A;  2ZH8 A;  3OGU A;  4UD5 A;  4K4H A;  4NXW A;  3UQ0 A;  4P4P A;  3NYB A;  3C2L A;  4M47 A;  4K4G A;  1VJ7 A;  8ICV A;  4I2J A;  4NLN A;  4RWP A;  2PBE A;  4M9J A;  5DB8 A;  1MIV A;  4KLG A;  4KLS A;  1KNY A;  9ICQ A;  5JTG A;  1ZJN A;  4R66 A;  3AU2 A;  4XUS A;  2BCV A;  2ZH7 A;  4Z6F A;  4KB6 A;  1BPX A;  1R8C A;  1ZQS A;  5HC9 A;  4FHX A;  4EP7 A;  4WC6 A;  2IHO A;  1JMS A;  3OUY A;  4R63 A;  7ICF A;  1ZQO A;  4DOA A;  2P66 A;  5J2H A;  4M9G A;  3HJ4 A;  3TFR A;  4RPZ A;  2M2V A;  5J2J A;  2FMS A;  2M2W A;  4GXJ A;  5J0R A;  5HRD A;  5DB9 A;  4KLO A;  9ICP A;  4LEY A;  4FHV A;  1ZQU A;  4F5Q A;  4TUQ A;  7ICU A;  3OVB A;  4R64 A;  4KLD A;  3H3A A;  7ICL A;  4WOY A;  9ICS A;  2ZH3 A;  4F5R A;  3JPT A;  4NXX A;  4WC0 A;  4RWO A;  3UQ2 A;  1JN3 A;  4MFA A;  3ISB A;  4K98 A;  1ZQK A;  3UPS A;  2BPF A;  4XA5 A;  4RWQ A;  4KLT A;  5D63 A;  4PHA A;  3WFR E;  2B4V A;  2ZH5 A;  8ICL A;  4IQT A;  3C2K A;  4UBB A;  3MCR A;  4MFC A;  3L9D A;  3UXP A;  1XSP A;  1KDH A;  3H38 A;  1MIW A;  3OVS A;  4XRH A;  5CHE A;  4X4P A;  8ICO A;  1MIY A;  2ZH4 A;  5J0P A;  3JPP A;  2GAF D;  7ICH A;  4UAZ A;  4I2B A;  3H37 A;  3LQC B;  7ICQ A;  9ICO A;  2BPC A;  5BPC A;  4NY8 A;  3AQM A;  4YD2 A;  8ICS A;  9ICG A;  9ICV A;  4NLZ A;  7ICR A;  2I9G A;  3HX0 A;  8ICB A;  2DR9 A;  5IIL A;  4QZE A;  2ZHA A;  4R65 A;  3AUO A;  1R89 A;  4M9H A;  2DRB A;  9ICH A;  7ICI A;  5EOZ A;  3RH4 A;  9ICK A;  4NXU A;  7ICE A;  9ICW A;  5DB6 A;  4AT7 B;  3MGH A;  3MDA A;  4UAW A;  1XSL A;  4E80 A;  4I0U A;  4FH5 A;  2BBH A;  4AT7 A;  3C5F A;  4EBK A;  7ICG A;  1F5A A;  1ZQP A;  9ICT A;  5J0Y A;  8ICA A;  4LT6 A;  5J2B A;  4I2D A;  2ISO A;  3RH6 A;  4X0A A;  4OAG A;  2NRK A;  7ICV A;  1ZJM A;  5CHG A;  5J0Q A;  4K9B A;  5J2F A;  8ICM A;  4KLE A;  4O9M A;  1HUZ A;  2HN1 A;  4RT2 A;  4RWN A;  4MF2 A;  5D62 A;  8ICZ A;  3RJK A;  4Z6C A;  1MQ2 A;  5DDM A;  4QZB A;  7ICP A;  4DOC A;  1ZQY A;  2PFQ A;  5DB7 A;  4OAF A;  4RPX A;  7ICS A;  5D46 A;  3UPQ A;  5HRB A;  3C66 A;  2DR5 A;  3MBY A;  4O5K A;  2O5A A;  4I2C A;  5IIM A;  4KLU A;  4O67 A;  3OUY B;  2FMP A;  4O6A A;  1TV9 A;  4I2F A;  4KLQ A;  8ICH A;  5HRE A;  5CFS A;  4WH5 A;  4QZA A;  1MQ3 A;  1Q79 A;  5HHH A;  4UB1 A;  4LEV A;  1BPY A;  3RJJ A;  4M04 A;  4S3N A;  1UEU A;  4EED A;  1ZQF A;  1TFW A;  4I28 A;  4I2I A;  5J2I A;  2FMQ A;  1ZQV A;  2DRA A;  4PGX A;  1ZQZ A;  4WCW A;  4P4O A;  1ZQQ A;  4X4S A;  2VAN A;  4JWM A;  3V7J A;  3NVO A;  1Q78 A;  1ZQL A;  5F2V O;  4RQ1 A;  5DDY A;  1TFY A;  3C18 A;  5IIO A;  4XQ8 A;  8ICX A;  3RJI A;  4K96 A;  4XQ7 A;  5HRF A;  4JLX A;  5J2K A;  2PFO A;  3AQN A;  2ZH2 A;  3C2M A;  7ICJ A;  4LZG A;  5CFT A;  3WFO A;  4QZI A;  8ICR A;  4P4M A;  1ZQN A;  4IG8 A;  3UXN A;  4WC1 A;  4N7R A;  4X4N A;  4YD1 A;  4NKU A;  3ER9 B;  8ICK A;  8ICI A;  2DR7 A;  4F5N A;  4RQ4 A;  4KLF A;  4E8F A;  5J0U A;  4PHE A;  4X0B A;  1WOT A;  8ICW A;  4PPX A;  4NM1 A;  3HW8 A;  2PFN A;  3UXO A;  2B51 A;  2O1P A;  5DEC A;  4WQL A;  4UB3 A;  8ICE A;  5CWR A;  8ICG A;  4AT9 B;  5J29 A;  4MF8 A;  9ICE A;  2W9M A;  4EV6 A;  4I2A A;  4RQ5 A;  2PFP A;  1UET A;  4TUP A;  4QZ8 A;  4AT9 A;  4F5O A;  3K75 D;  4WBY A;  2BCR A;  4RQ6 A;  3AU6 A;  4YMM A;  5DBA A;  4O68 A;  4X4T A;  4IQV A;  3JYY A;  4UB2 A;  2BPG A;  3ISD A;  4X4U A;  4LZD A;  2DVI A;  4AT8 B;  4O69 A;  3JPO A;  4XJE A;  4P2H A;  1GPJ A;  2BBJ A;  7ICO A;  4K4I A;  4TUS A;  2Q66 A;  4YMN A;  4NXT A;  4UD4 A;  2DR8 A;  4AT8 A;  2BE3 A;  4O5E A;  4X4O A;  1BPE A;  5III A;  1ZQX A;  1ZQW A;  3H39 A;  5HRI A;  4NM2 A;  1ZQR A;  4I2H A;  5HHI A;  2HHP A;  4DO9 A;  3WFQ E;  4JWN A;  5HR9 A;  4K97 A;  4KM5 A;  4QZD A;  4I27 A;  4KLI A;  4FH3 A;  4PGQ A;  3PHZ A;  5BOL A;  3TFS A;  4YN4 A;  2IHM A;  4QZC A;  3HJ1 A;  4FHW A;  4FO6 A;  3EF2 A;  3AQK A;  3NWI A;  4IQW A;  3PMN A;  3RJG A;  4X4R A;  4FHP A;  4UBC A;  2ZH6 A;  3AQL A;  4JLZ A;  1ZQC A;  8ICY A;  1ZQE A;  8ICF A;  3OV7 A;  7ICM A;  4IQU A;  5J0S A;  4GXK A;  7ICK A;  5IIK A;  5CR0 A;  3RJE A;  2BCS A;  3V7K A;  8ICU A;  4OAI Z;  1YLQ A;  4RQ8 A;  1ZQH A;  2GWS A;  2ID1 A;  4DOB A;  1NOM A;  4LEZ A;  4I2G A;  4PHD A;  9ICJ A;  4Z6D A;  4UAY A;  8ICT A;  9ICC A;  1BPB A;  4K8V A;  1BPD A;  4FHY A;  3C5G A;  3OVA A;  1JQR A;  9ICB A;  1ZQI A;  2BCQ A;  4RQ7 A;  4TUR A;  4I2E A;  4WQK A;  3JZ0 A;  3MDC A;  3HWT A;  8ICN A;  9ICA A;  1ZQB A;  3V7L A;  1KEJ A;  4MFF A;  5IIN A;  4E7X A;  2IUB A;  3JPQ A;  4WC7 A;  4LVS A;  4Z6E A;  2M2U A;  4YMO A;  4X4Q A;  5CFU A;  3OWG A;  2ZHB A;  3RJH A;  4RPY A;  7ICN A;  1OU5 A;  5DED A;  7ICT A;  4PH5 A;  3MGI A;  1XSN A;  4UB4 A;  3WFP A;  5B3P A;  4HX0 A;  4GXI A;  4K99 A;  3GDX A;  8ICP A;  4LEW A;  1ZQD A;  4EGW A;  4WC3 A;  4KLJ A;  5DBB A;  5IIJ A;  3K7D A;  2RFF A;  5J0O A;  2ISP A;  2M2T A;  5J2G A;  8ICC A; 
#chains in the Genus database with same CATH homology
 4X4U A;  4FHX A;  2DVI A;  4AT8 B;  4O69 A;  4EP7 A;  4X4V A;  4XJE A;  2EWR A;  1GPJ A;  2IHO A;  3OUY A;  2Q66 A;  4NXT A;  4UD4 A;  3HJ4 A;  2DR8 A;  4AT8 A;  5D62 A;  2B56 A;  4X4O A;  4OAF A;  1FA0 A;  3C66 A;  2DR5 A;  1R8A A;  2HHP A;  4LEY A;  4FHV A;  4OAH A;  4O67 A;  3OUY B;  3OVB A;  4O6A A;  4K97 A;  4FO1 A;  1UEV A;  5CFS A;  4WH5 A;  4KM5 A;  4WOY A;  1Q79 A;  4FH3 A;  2ZH3 A;  3ERC C;  4LEV A;  4NXX A;  2ZH1 A;  3ER8 C;  3PHZ A;  4K9A A;  1UEU A;  2ZH9 A;  5D61 A;  4K98 A;  1TFW A;  3HJ1 A;  4FHW A;  2DRA A;  3EF2 A;  5D63 A;  4X4S A;  2B4V A;  2ZH5 A;  5B3Q A;  1Q78 A;  4FHP A;  4X4R A;  3MCR A;  2ZH6 A;  4JLZ A;  4ATB B;  1TFY A;  3OV7 A;  3HIY A;  3OVS A;  5CHE A;  4X4P A;  4K96 A;  4JLX A;  4ATB A;  2ZH4 A;  4OAI Z;  2ZH2 A;  2FCL A;  2GAF D;  4NXV A;  5CFT A;  3NKU A;  4LEZ A;  4M5D A;  4K8V A;  4N7R A;  4FHY A;  3OVA A;  4X4N A;  2GA9 D;  1R8B A;  4NKU A;  3ER9 B;  2DR7 A;  4NKT A;  4WQK A;  2DR9 A;  4E8F A;  4MKP A;  2ZHA A;  4E7X A;  1R89 A;  2DRB A;  4NXU A;  2B51 A;  2O1P A;  4X4Q A;  2ZH8 A;  4UD5 A;  5CFU A;  4AT7 B;  4WQL A;  4NXW A;  3OWG A;  4AT9 B;  2ZHB A;  3NYB A;  4E80 A;  4FH5 A;  1UET A;  4AT7 A;  4AT9 A;  1F5A A;  5B3P A;  4HX0 A;  4LT6 A;  4K99 A;  4LEW A;  4OAG A;  3K7D A;  4O68 A;  2ZH7 A;  4X4T A;  4KB6 A;  4K9B A;  1R8C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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