4AVMA

Crystal structure of the n-bar domain of human bridging integrator 2.
Total Genus 110
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
110
sequence length
230
structure length
230
Chain Sequence
KQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHKLYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLADQAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNKAQTVFEDLNQELLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLERQHSN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the N-Bar Domain of Human Bridging Integrator 2.
rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords BRIDGING INTEGRATOR 2
total genus 110
structure length 230
sequence length 230
ec nomenclature
pdb deposition date 2012-05-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03114 BAR BAR domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 4avmA00
3QNIA 2YKTA 4WPEA 2FICA 1WDZA 2D4CA 1X03A 1ZWWA 2Q12A 4FZSA 3Q0KA 2RAIA 3CAZA 3ACOA 3DYTA 4H8SA 3G9GA 1I4LA 4BNEA 4DYLA 1I4TA 2D1LA 4I1QA 3PLTA 1Y2OA 3ABHA 4NSWA 3HAIA 2X3VA 1X04A 3HAJA 2X3XA 3SOGA 2RAJA 2Z0NA 3QWEA 3I2WA 3QE6A 3SYVA 4AKVA 2Z0OA 2EFLA 2EFKA 3Q84A 4AVMA 2Q13A 3HAHA 3M3WA 4WPCA 1URUA 3OK8A 3LLLA 4ATMA 2V0OA 5C5BA 2C08A 2X3WA 2RAKA 5C5BB 2ELBA 2Z0VA 1I4DA 1I49A 4DCNC 4NQIA
chains in the Genus database with same CATH superfamily
5KBPA 3ZEDA 4DYLA 2F1BA 4AZ6A 4JL9A 4EZSA 4R5GA 4AKVA 3DPOA 2YIAA 1GNLA 2QFFA 4EZYA 1QWNA 3OK8A 3FD9A 2C08A 4E81A 2Z0VA 1LQ7A 1WDZA 2Q12A 1HWWA 4BNEA 4E3CA 3ABHA 3SOGA 3EJTA 4PO2A 1O7DC 4EZUA 2WINM 3DX4A 2LM0A 1URUA 4IWOA 4AZCA 3BUIA 2YI8A 3D51A 4KIKA 4EZWA 3EJQA 3T4AG 2ND1A 1TQTA 3O3OB 4IM2A 2F7RA 2X3XA 3SYVA 3O3MB 3DX1A 3D50A 1QX1A 4FZPA 4EZXA 1GNTA 2PMRA 4HY9A 4EZNA 1SU8A 3BVTA 3DDFA 4JN4A 2EFKA 1JQKA 2ZXQA 3OHXM 2YIBA 4R5LA 2F7OA 3T49A 3I01A 1R34A 3ERCC 4H8SA 3ACOA 4JNEA 4R5IA 4EZPA 3CV5A 4AZIA 3DPPA 4HR1B 2Z0NA 3BUPA 3BUDA 3T47A 3D52A 3BVWA 3LLLA 4IM3A 1QWUA 3RV1A 1DKXA 4EZRA 4AZ7A 1I4LA 1R5EA 2OBMA 1TQVA 4R5JA 3BVXA 4AVMA 1GN9A 2LXYA 4ATMA 4IWQA 1U00A 4FZSA 3F7WA 3CKDA 2YL6A 3PLTA 3BVVA 3DDGA 1Y2OA 4IM0A 3L3OM 3B51X 1O7DB 2PY6A 4AZCB 2Z8YA 2F18A 2RAIA 3DYTA 2F7PA 2D1LA 3KAWA 4JLCA 4AZGA 4KIKB 3UITA 4R5KA 2OW7A 1SU7A 2O0I1 4EZOA 2YI9A 2GF4A 2OBLA 3T48A 2QXLA 3RV0A 4DCNC 4WPEA 2MI7A 1W9MA 3CAZA 3DX2A 4F01A 2OZNB 3BVUA 4EZZA 2Z0OA 2EFLA 4H6IA 2OO2A 3O3NB 2X3WA 4UDXX 4FM3A 2ELBA 1I4DA 4EZQA 3EJPA 2D4CA 3BLBA 1ZYLA 2WYIA 4F00A 3HAIA 3ER8C 2X3VA 2NCZA 3D2EA 4B9QA 3M3WA 1OA1A 4G6QA 1TQUA 4JNFA 5C5BA 2JNSA 4FZOA 2ND0A 3EJSA 2FICA 4AZBA 5TKYA 2EWFA 3LMFA 3OWGA 4I1QA 4JWIA 2YLLA 1R33A 4WPCA 3C7NA 1SUFA 3D4ZA 2N3KA 2ALWA 3G9GA 4AZ5A 3HAJA 2F1AA 3D4YA 1TQSA 2QKWA 3D2FA 3I39X 3HAHA 2YLAA 2EX3B 3B53X 4JWDA 3KDRA 1I49A 1DKZA 4NQIA 1X03A 4EZTA 3CVRA 3Q0KA 4HYBA 2JNKA 3BUQA 3Q84A 3LVTA 3KAVA 1PS3A 4NPHA 4IW0A 4UDYX 1OA0A 2YKTA 4D8JA 4IWPA 1ZWWA 3B52X 1OAOA 3BUBA 1I4TA 4NSWA 2FYVA 1X04A 2RAJA 3QWEA 3I2WA 1SU6A 1TQWA 3CZNA 2X5CA 3QNJA 2YL5A 3DX3A 3VKHA 2YL9A 2YIVX 2OW6A 3EJRA 1E2UA 3QNIA 3DX0A 5FIGA 1HTYA 3RPMA 3GI7A 3DPQA 2GA9D 2GAFD 2F7QA 4H6HA 3EJUA 3QE6A 2Q13A 1MJGA 5C5BB 4AZHA 4JWEA 5E84A 3A98A 2RT6A 4M0MA 2KHOA 4EZVA 2YL8A 4HR1A 1E1DA 3CZSA 4JWCA 3VEBA 2WYHA 1YWMA 1HXKA 3VEAA 1E9VA 5FLEX 3I04A 3ER9B 3L3PA 3T46A 1DKYA 2V0OA 3QA8A 1UPXA 2RAKA
chains in the Genus database with same CATH topology
3QNIA 2YKTA 4WPEA 2FICA 1WDZA 2D4CA 1X03A 1ZWWA 2Q12A 4FZSA 3Q0KA 2RAIA 3CAZA 3ACOA 3DYTA 4H8SA 3G9GA 1I4LA 4BNEA 4DYLA 1I4TA 2D1LA 4I1QA 3PLTA 1Y2OA 3ABHA 4NSWA 3HAIA 2X3VA 1X04A 3HAJA 2X3XA 3SOGA 2RAJA 2Z0NA 3QWEA 3I2WA 3QE6A 3SYVA 4AKVA 2Z0OA 2EFLA 2EFKA 3Q84A 4AVMA 2Q13A 3HAHA 3M3WA 4WPCA 1URUA 3OK8A 3LLLA 4ATMA 2V0OA 5C5BA 2C08A 2X3WA 2RAKA 5C5BB 2ELBA 2Z0VA 1I4DA 1I49A 4DCNC 4NQIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QNI A;  2YKT A;  4WPE A;  2FIC A;  1WDZ A;  2D4C A;  1X03 A;  1ZWW A;  2Q12 A;  4FZS A;  3Q0K A;  2RAI A;  3CAZ A;  3ACO A;  3DYT A;  4H8S A;  3G9G A;  1I4L A;  4BNE A;  4DYL A;  1I4T A;  2D1L A;  4I1Q A;  3PLT A;  1Y2O A;  3ABH A;  4NSW A;  3HAI A;  2X3V A;  1X04 A;  3HAJ A;  2X3X A;  3SOG A;  2RAJ A;  2Z0N A;  3QWE A;  3I2W A;  3QE6 A;  3SYV A;  4AKV A;  2Z0O A;  2EFL A;  2EFK A;  3Q84 A;  4AVM A;  2Q13 A;  3HAH A;  3M3W A;  4WPC A;  1URU A;  3OK8 A;  3LLL A;  4ATM A;  2V0O A;  5C5B A;  2C08 A;  2X3W A;  2RAK A;  5C5B B;  2ELB A;  2Z0V A;  1I4D A;  1I49 A;  4DCN C;  4NQI A; 
#chains in the Genus database with same CATH topology
 5KBP A;  3ZED A;  4DYL A;  2F1B A;  4AZ6 A;  4JL9 A;  4EZS A;  4R5G A;  4AKV A;  3DPO A;  2YIA A;  1GNL A;  2QFF A;  4EZY A;  1QWN A;  3OK8 A;  3FD9 A;  2C08 A;  4E81 A;  2Z0V A;  1LQ7 A;  1WDZ A;  2Q12 A;  1HWW A;  4BNE A;  4E3C A;  3ABH A;  3SOG A;  3EJT A;  4PO2 A;  1O7D C;  4EZU A;  2WIN M;  3DX4 A;  2LM0 A;  1URU A;  4IWO A;  4AZC A;  3BUI A;  2YI8 A;  3D51 A;  4KIK A;  4EZW A;  3EJQ A;  3T4A G;  2ND1 A;  1TQT A;  3O3O B;  4IM2 A;  2F7R A;  2X3X A;  3SYV A;  3O3M B;  3DX1 A;  3D50 A;  1QX1 A;  4FZP A;  4EZX A;  1GNT A;  2PMR A;  4HY9 A;  4EZN A;  1SU8 A;  3BVT A;  3DDF A;  4JN4 A;  2EFK A;  1JQK A;  2ZXQ A;  3OHX M;  2YIB A;  4R5L A;  2F7O A;  3T49 A;  3I01 A;  1R34 A;  3ERC C;  4H8S A;  3ACO A;  4JNE A;  4R5I A;  4EZP A;  3CV5 A;  4AZI A;  3DPP A;  4HR1 B;  2Z0N A;  3BUP A;  3BUD A;  3T47 A;  3D52 A;  3BVW A;  3LLL A;  4IM3 A;  1QWU A;  3RV1 A;  1DKX A;  4EZR A;  4AZ7 A;  1I4L A;  1R5E A;  2OBM A;  1TQV A;  4R5J A;  3BVX A;  4AVM A;  1GN9 A;  2LXY A;  4ATM A;  4IWQ A;  1U00 A;  4FZS A;  3F7W A;  3CKD A;  2YL6 A;  3PLT A;  3BVV A;  3DDG A;  1Y2O A;  4IM0 A;  3L3O M;  3B51 X;  1O7D B;  2PY6 A;  4AZC B;  2Z8Y A;  2F18 A;  2RAI A;  3DYT A;  2F7P A;  2D1L A;  3KAW A;  4JLC A;  4AZG A;  4KIK B;  3UIT A;  4R5K A;  2OW7 A;  1SU7 A;  2O0I 1;  4EZO A;  2YI9 A;  2GF4 A;  2OBL A;  3T48 A;  2QXL A;  3RV0 A;  4DCN C;  4WPE A;  2MI7 A;  1W9M A;  3CAZ A;  3DX2 A;  4F01 A;  2OZN B;  3BVU A;  4EZZ A;  2Z0O A;  2EFL A;  4H6I A;  2OO2 A;  3O3N B;  2X3W A;  4UDX X;  4FM3 A;  2ELB A;  1I4D A;  4EZQ A;  3EJP A;  2D4C A;  3BLB A;  1ZYL A;  2WYI A;  4F00 A;  3HAI A;  3ER8 C;  2X3V A;  2NCZ A;  3D2E A;  4B9Q A;  3M3W A;  1OA1 A;  4G6Q A;  1TQU A;  4JNF A;  5C5B A;  2JNS A;  4FZO A;  2ND0 A;  3EJS A;  2FIC A;  4AZB A;  5TKY A;  2EWF A;  3LMF A;  3OWG A;  4I1Q A;  4JWI A;  2YLL A;  1R33 A;  4WPC A;  3C7N A;  1SUF A;  3D4Z A;  2N3K A;  2ALW A;  3G9G A;  4AZ5 A;  3HAJ A;  2F1A A;  3D4Y A;  1TQS A;  2QKW A;  3D2F A;  3I39 X;  3HAH A;  2YLA A;  2EX3 B;  3B53 X;  4JWD A;  3KDR A;  1I49 A;  1DKZ A;  4NQI A;  1X03 A;  4EZT A;  3CVR A;  3Q0K A;  4HYB A;  2JNK A;  3BUQ A;  3Q84 A;  3LVT A;  3KAV A;  1PS3 A;  4NPH A;  4IW0 A;  4UDY X;  1OA0 A;  2YKT A;  4D8J A;  4IWP A;  1ZWW A;  3B52 X;  1OAO A;  3BUB A;  1I4T A;  4NSW A;  2FYV A;  1X04 A;  2RAJ A;  3QWE A;  3I2W A;  1SU6 A;  1TQW A;  3CZN A;  2X5C A;  3QNJ A;  2YL5 A;  3DX3 A;  3VKH A;  2YL9 A;  2YIV X;  2OW6 A;  3EJR A;  1E2U A;  3QNI A;  3DX0 A;  5FIG A;  1HTY A;  3RPM A;  3GI7 A;  3DPQ A;  2GA9 D;  2GAF D;  2F7Q A;  4H6H A;  3EJU A;  3QE6 A;  2Q13 A;  1MJG A;  5C5B B;  4AZH A;  4JWE A;  5E84 A;  3A98 A;  2RT6 A;  4M0M A;  2KHO A;  4EZV A;  2YL8 A;  4HR1 A;  1E1D A;  3CZS A;  4JWC A;  3VEB A;  2WYH A;  1YWM A;  1HXK A;  3VEA A;  1E9V A;  5FLE X;  3I04 A;  3ER9 B;  3L3P A;  3T46 A;  1DKY A;  2V0O A;  3QA8 A;  1UPX A;  2RAK A; 
#chains in the Genus database with same CATH homology
 3QNI A;  2YKT A;  4WPE A;  2FIC A;  1WDZ A;  2D4C A;  1X03 A;  1ZWW A;  2Q12 A;  4FZS A;  3Q0K A;  2RAI A;  3CAZ A;  3ACO A;  3DYT A;  4H8S A;  3G9G A;  1I4L A;  4BNE A;  4DYL A;  1I4T A;  2D1L A;  4I1Q A;  3PLT A;  1Y2O A;  3ABH A;  4NSW A;  3HAI A;  2X3V A;  1X04 A;  3HAJ A;  2X3X A;  3SOG A;  2RAJ A;  2Z0N A;  3QWE A;  3I2W A;  3QE6 A;  3SYV A;  4AKV A;  2Z0O A;  2EFL A;  2EFK A;  3Q84 A;  4AVM A;  2Q13 A;  3HAH A;  3M3W A;  4WPC A;  1URU A;  3OK8 A;  3LLL A;  4ATM A;  2V0O A;  5C5B A;  2C08 A;  2X3W A;  2RAK A;  5C5B B;  2ELB A;  2Z0V A;  1I4D A;  1I49 A;  4DCN C;  4NQI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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