4BNEA

Pacsin2 interacts with membranes and actin-filaments
Total Genus 127
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
127
sequence length
290
structure length
290
Chain Sequence
SDSFWEVGNYKRTVKRIDDGHRLCNDLMNCIHERARIEKVYAQQLTEWAKRWKQLVEKGPQYGTVERAWCAFMSEAEKVSELHLEVKGSLMNEDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAYHAACKEEKLAISRETNSKADPALNPEQLKKLQDKVERSKQDVLKTKAKYEKSLKELDNATPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVASYKNIYRELEQNIKTADAVEDLRWFRANQGPGMSMNWPQFEDD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Direct Interaction of Actin Filaments with F-Bar Protein Pacsin2.
pubmed doi rcsb
molecule tags Endocytosis
source organism Gallus gallus
molecule keywords PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROT
total genus 127
structure length 290
sequence length 290
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-05-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00018 SH3_1 SH3 domain
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 4bneA01
1I4TA 1WDZA 3M3WA 2Z0VA 4FZSA 2FICA 2RAIA 2RAKA 2Z0OA 2V0OA 2X3VA 3QNIA 4BNEA 1I4LA 4WPCA 2D1LA 2Q12A 2EFLA 2Q13A 3HAHA 1URUA 2C08A 2RAJA 3HAIA 4AKVA 3ABHA 3SYVA 4DYLA 1X04A 3G9GA 3QWEA 4NSWA 3QE6A 4AVMA 3DYTA 3PLTA 1I49A 1X03A 1Y2OA 3CAZA 2ELBA 4NQIA 4WPEA 2X3XA 4I1QA 2D4CA 5C5BB 4DCNC 5C5BA 3SOGA 1ZWWA 1I4DA 3ACOA 2X3WA 4ATMA 3OK8A 3HAJA 3LLLA 4H8SA 2YKTA 3Q0KA 2Z0NA 3I2WA 2EFKA 3Q84A
chains in the Genus database with same CATH superfamily
3BUQA 3DDFA 2F7QA 2YIAA 4EZQA 2YLAA 2RAJA 3ABHA 3PLTA 2YIBA 1I4DA 2QKWA 3BVXA 1TQSA 3D4YA 3EJPA 4R5LA 3OHXM 4JWCA 5FIGA 2YL5A 1O7DC 1X04A 4UDYX 1UPXA 4FM3A 3I04A 1DKZA 2OO2A 1PS3A 2LXYA 4AZGA 2X3VA 4WPCA 2Q12A 3L3PA 1SU6A 3T4AG 2QXLA 1SU8A 2X5CA 4EZSA 1MJGA 3QNJA 4D8JA 3O3MB 5TKYA 2GA9D 3BVTA 3D50A 3T46A 3CZNA 4EZYA 3QWEA 3DPOA 3BUDA 3CAZA 4JLCA 3DX2A 3I01A 1YWMA 1ZWWA 2JNSA 3EJRA 1DKYA 3BUPA 2WYHA 1QX1A 4EZTA 3BVUA 1QWUA 3HAHA 1URUA 3D4ZA 3GI7A 1TQVA 3KAVA 3RV0A 3QA8A 1GN9A 4G6QA 2KHOA 4IW0A 1TQWA 1O7DB 4FZOA 3T48A 4EZNA 3DX1A 4R5GA 2Z0OA 1HWWA 3O3NB 4KIKB 3D2EA 2OW7A 1OA0A 3ER9B 3LMFA 4NSWA 3DPPA 3EJUA 3DX4A 1GNTA 1R34A 2X3WA 2YL8A 2Z0NA 4JN4A 3BUBA 3CZSA 2FYVA 1HXKA 4EZWA 3B53X 2YLLA 3B52X 2YL6A 2JNKA 3QNIA 4KIKA 2Q13A 3I39X 3D52A 4R5JA 3DYTA 4WPEA 4EZXA 2OBLA 2NCZA 2F7OA 2RT6A 1TQTA 2YKTA 3D2FA 4EZUA 4UDXX 2V0OA 2F1BA 3HAIA 4E81A 4IM3A 3BUIA 4JL9A 3SOGA 2F7RA 2YI8A 3OK8A 3KAWA 4H8SA 5E84A 3ERCC 4PO2A 2EWFA 1U00A 3M3WA 4AZ7A 1E2UA 1R33A 4EZOA 2Z8YA 2QFFA 2OW6A 4IWQA 3LVTA 2D4CA 3ACOA 2ND1A 4HY9A 1GNLA 4IM0A 1JQKA 2LM0A 2WYIA 3CVRA 3A98A 3UITA 3VEBA 3I2WA 3D51A 1OA1A 1LQ7A 3EJQA 4HR1B 5C5BB 1DKXA 4EZPA 4F00A 1ZYLA 4AZCB 3EJTA 2YI9A 3L3OM 4ATMA 3HAJA 3CV5A 3Q0KA 1SUFA 4JNFA 1HTYA 5KBPA 2C08A 3ER8C 4AKVA 3BVVA 3DX0A 1R5EA 3VKHA 2RAKA 4BNEA 2EFLA 3DPQA 1SU7A 4FZPA 4JWIA 3KDRA 2ELBA 2ZXQA 2F7PA 2YL9A 2F1AA 3BVWA 1QWNA 3CKDA 2O0I1 2FICA 1E9VA 3EJSA 4H6HA 3DDGA 4HYBA 5FLEX 4IM2A 1Y2OA 3VEAA 2OZNB 4AZIA 1TQUA 4IWOA 4DCNC 3T49A 3FD9A 2GAFD 4AZBA 2PMRA 3B51X 4FZSA 1I4LA 4AZ6A 3RV1A 2GF4A 3G9GA 4AVMA 2OBMA 4JWDA 1I49A 2F18A 4NPHA 4F01A 4EZVA 3LLLA 4R5KA 4JNEA 2YIVX 4M0MA 2RAIA 2ND0A 2WINM 3BLBA 2D1LA 4H6IA 4B9QA 3QE6A 1X03A 4NQIA 4EZRA 3DX3A 2N3KA 2PY6A 4AZ5A 4E3CA 1E1DA 4JWEA 3C7NA 1I4TA 1WDZA 3RPMA 2Z0VA 2EX3B 4EZZA 1W9MA 3SYVA 4DYLA 3T47A 3Q84A 2MI7A 4HR1A 2X3XA 4I1QA 1OAOA 5C5BA 4AZCA 4IWPA 3F7WA 3OWGA 4AZHA 3O3OB 2ALWA 3ZEDA 2EFKA 4R5IA
chains in the Genus database with same CATH topology
1I4TA 1WDZA 3M3WA 2Z0VA 4FZSA 2FICA 2RAIA 2RAKA 2Z0OA 2V0OA 2X3VA 3QNIA 4BNEA 1I4LA 4WPCA 2D1LA 2Q12A 2EFLA 2Q13A 3HAHA 1URUA 2C08A 2RAJA 3HAIA 4AKVA 3ABHA 3SYVA 4DYLA 1X04A 3G9GA 3QWEA 4NSWA 3QE6A 4AVMA 3DYTA 3PLTA 1I49A 1X03A 1Y2OA 3CAZA 2ELBA 4NQIA 4WPEA 2X3XA 4I1QA 2D4CA 5C5BB 4DCNC 5C5BA 3SOGA 1ZWWA 1I4DA 3ACOA 2X3WA 4ATMA 3OK8A 3HAJA 3LLLA 4H8SA 2YKTA 3Q0KA 2Z0NA 3I2WA 2EFKA 3Q84A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I4T A;  1WDZ A;  3M3W A;  2Z0V A;  4FZS A;  2FIC A;  2RAI A;  2RAK A;  2Z0O A;  2V0O A;  2X3V A;  3QNI A;  4BNE A;  1I4L A;  4WPC A;  2D1L A;  2Q12 A;  2EFL A;  2Q13 A;  3HAH A;  1URU A;  2C08 A;  2RAJ A;  3HAI A;  4AKV A;  3ABH A;  3SYV A;  4DYL A;  1X04 A;  3G9G A;  3QWE A;  4NSW A;  3QE6 A;  4AVM A;  3DYT A;  3PLT A;  1I49 A;  1X03 A;  1Y2O A;  3CAZ A;  2ELB A;  4NQI A;  4WPE A;  2X3X A;  4I1Q A;  2D4C A;  5C5B B;  4DCN C;  5C5B A;  3SOG A;  1ZWW A;  1I4D A;  3ACO A;  2X3W A;  4ATM A;  3OK8 A;  3HAJ A;  3LLL A;  4H8S A;  2YKT A;  3Q0K A;  2Z0N A;  3I2W A;  2EFK A;  3Q84 A; 
#chains in the Genus database with same CATH topology
 3BUQ A;  3DDF A;  2F7Q A;  2YIA A;  4EZQ A;  2YLA A;  2RAJ A;  3ABH A;  3PLT A;  2YIB A;  1I4D A;  2QKW A;  3BVX A;  1TQS A;  3D4Y A;  3EJP A;  4R5L A;  3OHX M;  4JWC A;  5FIG A;  2YL5 A;  1O7D C;  1X04 A;  4UDY X;  1UPX A;  4FM3 A;  3I04 A;  1DKZ A;  2OO2 A;  1PS3 A;  2LXY A;  4AZG A;  2X3V A;  4WPC A;  2Q12 A;  3L3P A;  1SU6 A;  3T4A G;  2QXL A;  1SU8 A;  2X5C A;  4EZS A;  1MJG A;  3QNJ A;  4D8J A;  3O3M B;  5TKY A;  2GA9 D;  3BVT A;  3D50 A;  3T46 A;  3CZN A;  4EZY A;  3QWE A;  3DPO A;  3BUD A;  3CAZ A;  4JLC A;  3DX2 A;  3I01 A;  1YWM A;  1ZWW A;  2JNS A;  3EJR A;  1DKY A;  3BUP A;  2WYH A;  1QX1 A;  4EZT A;  3BVU A;  1QWU A;  3HAH A;  1URU A;  3D4Z A;  3GI7 A;  1TQV A;  3KAV A;  3RV0 A;  3QA8 A;  1GN9 A;  4G6Q A;  2KHO A;  4IW0 A;  1TQW A;  1O7D B;  4FZO A;  3T48 A;  4EZN A;  3DX1 A;  4R5G A;  2Z0O A;  1HWW A;  3O3N B;  4KIK B;  3D2E A;  2OW7 A;  1OA0 A;  3ER9 B;  3LMF A;  4NSW A;  3DPP A;  3EJU A;  3DX4 A;  1GNT A;  1R34 A;  2X3W A;  2YL8 A;  2Z0N A;  4JN4 A;  3BUB A;  3CZS A;  2FYV A;  1HXK A;  4EZW A;  3B53 X;  2YLL A;  3B52 X;  2YL6 A;  2JNK A;  3QNI A;  4KIK A;  2Q13 A;  3I39 X;  3D52 A;  4R5J A;  3DYT A;  4WPE A;  4EZX A;  2OBL A;  2NCZ A;  2F7O A;  2RT6 A;  1TQT A;  2YKT A;  3D2F A;  4EZU A;  4UDX X;  2V0O A;  2F1B A;  3HAI A;  4E81 A;  4IM3 A;  3BUI A;  4JL9 A;  3SOG A;  2F7R A;  2YI8 A;  3OK8 A;  3KAW A;  4H8S A;  5E84 A;  3ERC C;  4PO2 A;  2EWF A;  1U00 A;  3M3W A;  4AZ7 A;  1E2U A;  1R33 A;  4EZO A;  2Z8Y A;  2QFF A;  2OW6 A;  4IWQ A;  3LVT A;  2D4C A;  3ACO A;  2ND1 A;  4HY9 A;  1GNL A;  4IM0 A;  1JQK A;  2LM0 A;  2WYI A;  3CVR A;  3A98 A;  3UIT A;  3VEB A;  3I2W A;  3D51 A;  1OA1 A;  1LQ7 A;  3EJQ A;  4HR1 B;  5C5B B;  1DKX A;  4EZP A;  4F00 A;  1ZYL A;  4AZC B;  3EJT A;  2YI9 A;  3L3O M;  4ATM A;  3HAJ A;  3CV5 A;  3Q0K A;  1SUF A;  4JNF A;  1HTY A;  5KBP A;  2C08 A;  3ER8 C;  4AKV A;  3BVV A;  3DX0 A;  1R5E A;  3VKH A;  2RAK A;  4BNE A;  2EFL A;  3DPQ A;  1SU7 A;  4FZP A;  4JWI A;  3KDR A;  2ELB A;  2ZXQ A;  2F7P A;  2YL9 A;  2F1A A;  3BVW A;  1QWN A;  3CKD A;  2O0I 1;  2FIC A;  1E9V A;  3EJS A;  4H6H A;  3DDG A;  4HYB A;  5FLE X;  4IM2 A;  1Y2O A;  3VEA A;  2OZN B;  4AZI A;  1TQU A;  4IWO A;  4DCN C;  3T49 A;  3FD9 A;  2GAF D;  4AZB A;  2PMR A;  3B51 X;  4FZS A;  1I4L A;  4AZ6 A;  3RV1 A;  2GF4 A;  3G9G A;  4AVM A;  2OBM A;  4JWD A;  1I49 A;  2F18 A;  4NPH A;  4F01 A;  4EZV A;  3LLL A;  4R5K A;  4JNE A;  2YIV X;  4M0M A;  2RAI A;  2ND0 A;  2WIN M;  3BLB A;  2D1L A;  4H6I A;  4B9Q A;  3QE6 A;  1X03 A;  4NQI A;  4EZR A;  3DX3 A;  2N3K A;  2PY6 A;  4AZ5 A;  4E3C A;  1E1D A;  4JWE A;  3C7N A;  1I4T A;  1WDZ A;  3RPM A;  2Z0V A;  2EX3 B;  4EZZ A;  1W9M A;  3SYV A;  4DYL A;  3T47 A;  3Q84 A;  2MI7 A;  4HR1 A;  2X3X A;  4I1Q A;  1OAO A;  5C5B A;  4AZC A;  4IWP A;  3F7W A;  3OWG A;  4AZH A;  3O3O B;  2ALW A;  3ZED A;  2EFK A;  4R5I A; 
#chains in the Genus database with same CATH homology
 1I4T A;  1WDZ A;  3M3W A;  2Z0V A;  4FZS A;  2FIC A;  2RAI A;  2RAK A;  2Z0O A;  2V0O A;  2X3V A;  3QNI A;  4BNE A;  1I4L A;  4WPC A;  2D1L A;  2Q12 A;  2EFL A;  2Q13 A;  3HAH A;  1URU A;  2C08 A;  2RAJ A;  3HAI A;  4AKV A;  3ABH A;  3SYV A;  4DYL A;  1X04 A;  3G9G A;  3QWE A;  4NSW A;  3QE6 A;  4AVM A;  3DYT A;  3PLT A;  1I49 A;  1X03 A;  1Y2O A;  3CAZ A;  2ELB A;  4NQI A;  4WPE A;  2X3X A;  4I1Q A;  2D4C A;  5C5B B;  4DCN C;  5C5B A;  3SOG A;  1ZWW A;  1I4D A;  3ACO A;  2X3W A;  4ATM A;  3OK8 A;  3HAJ A;  3LLL A;  4H8S A;  2YKT A;  3Q0K A;  2Z0N A;  3I2W A;  2EFK A;  3Q84 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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