4I1QA

Crystal structure of hbrap1 n-bar domain
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
200
structure length
200
Chain Sequence
KDERFEQSANNFYQQQAEGHKLYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLADQAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNKAQTVFEDLNQELLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Bin2 Is a Membrane Sculpting N-BAR Protein That Influences Leucocyte Podosomes, Motility and Phagocytosis
pubmed doi rcsb
molecule tags Cell adhesion
source organism Homo sapiens
molecule keywords Bridging integrator 2
total genus 89
structure length 200
sequence length 200
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-11-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 4i1qA00
4DCNC 3DYTA 3SYVA 1URUA 2Q12A 1I4DA 2EFKA 1WDZA 3ABHA 4WPEA 1I4TA 1X03A 3LLLA 3PLTA 3CAZA 4H8SA 4NSWA 4WPCA 2D4CA 4AKVA 3QWEA 3Q84A 4NQIA 1I49A 1I4LA 2X3XA 3HAHA 3I2WA 3G9GA 2ELBA 1Y2OA 2D1LA 3HAIA 3HAJA 2X3VA 4BNEA 2RAJA 2X3WA 3OK8A 3ACOA 2Z0VA 3Q0KA 4DYLA 3QE6A 2RAIA 2YKTA 2Z0NA 4AVMA 5C5BB 2EFLA 2V0OA 3QNIA 4FZSA 2Z0OA 5C5BA 2Q13A 1ZWWA 2FICA 4ATMA 4I1QA 2RAKA 1X04A 3M3WA 3SOGA 2C08A
chains in the Genus database with same CATH superfamily
3D4ZA 3B51X 4R5IA 1I4DA 3BVXA 4JNFA 3F7WA 3VKHA 4R5JA 3O3NB 1GN9A 3DDGA 4M0MA 3DX4A 3OK8A 2WINM 2F1BA 3RPMA 2PY6A 3EJUA 1TQWA 2OZNB 4EZZA 3ZEDA 2N3KA 1LQ7A 1E9VA 4H8SA 4EZOA 4EZSA 1YWMA 2OW7A 3A98A 1I49A 2FYVA 1Y2OA 3HAJA 3FD9A 3L3OM 3CZNA 3VEAA 2YLLA 4NPHA 3BVUA 1OA1A 2EX3B 2F7RA 2YI8A 4PO2A 4JWDA 1E2UA 3SYVA 3EJRA 1W9MA 2OBMA 5TKYA 2QXLA 4JN4A 2F7PA 4EZPA 5C5BB 1QWUA 4HR1A 2ALWA 2JNSA 3D51A 2WYIA 2Q12A 3KAVA 3I04A 2GA9D 3HAHA 4KIKB 4AZ6A 2GAFD 3RV0A 4EZVA 4E3CA 4IWPA 3DX0A 3LMFA 4IM3A 3DX1A 3EJSA 3SOGA 4JL9A 3CV5A 2LXYA 1WDZA 3T46A 1DKXA 2OBLA 3EJTA 1UPXA 4BNEA 4UDYX 3QE6A 3ERCC 4JLCA 3QNIA 3D2EA 2ND0A 4I1QA 4EZUA 1R33A 2F7QA 2OO2A 1OAOA 5FIGA 4HY9A 3B52X 3QA8A 2D1LA 5E84A 3D52A 1DKYA 3T47A 2OW6A 4R5LA 2Q13A 1DKZA 3DDFA 2YL9A 3LLLA 1SU6A 4NSWA 2KHOA 4G6QA 3HAIA 3KAWA 4JWIA 4AZIA 2F1AA 4DYLA 2YKTA 4AZCB 4FZOA 5C5BA 4H6IA 1GNLA 4WPCA 3I01A 4IWOA 1SUFA 4IW0A 1R5EA 3T48A 2ELBA 4KIKA 2QFFA 3BUDA 2EWFA 4ATMA 1X04A 3DX2A 3UITA 1X03A 1R34A 3QNJA 2X3VA 3DPQA 2RAJA 3BVTA 3RV1A 3T49A 3B53X 3D50A 3ER9B 2Z8YA 1URUA 4R5GA 1MJGA 3OHXM 3BUPA 3D2FA 3BVWA 4JWEA 1QX1A 3BVVA 1O7DB 2WYHA 2Z0NA 4FZPA 2YI9A 3EJPA 2MI7A 3I39X 4WPEA 2C08A 1HXKA 3BUIA 3D4YA 1TQTA 1I4TA 3PLTA 1U00A 3CAZA 1ZYLA 3G9GA 1SU7A 3DX3A 4AZBA 4AZGA 4EZTA 4EZXA 4IM0A 5FLEX 1E1DA 4AZCA 4H6HA 2YL5A 3VEBA 1TQUA 3ABHA 3T4AG 4EZYA 2PMRA 3BUBA 4EZNA 1I4LA 1TQSA 3I2WA 4EZQA 4B9QA 1JQKA 3EJQA 2V0OA 4R5KA 1ZWWA 2YIAA 3M3WA 4IM2A 2NCZA 2GF4A 3OWGA 4D8JA 2ND1A 2F7OA 4JNEA 4EZRA 3C7NA 4EZWA 2Z0VA 3Q0KA 2X5CA 2F18A 2RAIA 4F01A 2YL6A 3BUQA 3LVTA 4E81A 3DYTA 5KBPA 4AZ7A 3O3OB 3BLBA 3CVRA 3QWEA 3Q84A 1TQVA 2RT6A 4AZ5A 4IWQA 2LM0A 3ACOA 4AVMA 2Z0OA 1HWWA 3CKDA 1SU8A 4FM3A 4DCNC 2YL8A 2QKWA 4AZHA 2D4CA 4AKVA 4NQIA 3KDRA 3DPPA 2X3WA 3CZSA 2ZXQA 1O7DC 4HR1B 4FZSA 3DPOA 2FICA 3L3PA 1PS3A 3GI7A 2JNKA 2EFKA 4HYBA 3O3MB 2O0I1 2YIVX 2X3XA 2YIBA 1OA0A 1GNTA 4JWCA 3ER8C 1HTYA 4F00A 1QWNA 2EFLA 4UDXX 2YLAA 2RAKA
chains in the Genus database with same CATH topology
4DCNC 3DYTA 3SYVA 1URUA 2Q12A 1I4DA 2EFKA 1WDZA 3ABHA 4WPEA 1I4TA 1X03A 3LLLA 3PLTA 3CAZA 4H8SA 4NSWA 4WPCA 2D4CA 4AKVA 3QWEA 3Q84A 4NQIA 1I49A 1I4LA 2X3XA 3HAHA 3I2WA 3G9GA 2ELBA 1Y2OA 2D1LA 3HAIA 3HAJA 2X3VA 4BNEA 2RAJA 2X3WA 3OK8A 3ACOA 2Z0VA 3Q0KA 4DYLA 3QE6A 2RAIA 2YKTA 2Z0NA 4AVMA 5C5BB 2EFLA 2V0OA 3QNIA 4FZSA 2Z0OA 5C5BA 2Q13A 1ZWWA 2FICA 4ATMA 4I1QA 2RAKA 1X04A 3M3WA 3SOGA 2C08A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DCN C;  3DYT A;  3SYV A;  1URU A;  2Q12 A;  1I4D A;  2EFK A;  1WDZ A;  3ABH A;  4WPE A;  1I4T A;  1X03 A;  3LLL A;  3PLT A;  3CAZ A;  4H8S A;  4NSW A;  4WPC A;  2D4C A;  4AKV A;  3QWE A;  3Q84 A;  4NQI A;  1I49 A;  1I4L A;  2X3X A;  3HAH A;  3I2W A;  3G9G A;  2ELB A;  1Y2O A;  2D1L A;  3HAI A;  3HAJ A;  2X3V A;  4BNE A;  2RAJ A;  2X3W A;  3OK8 A;  3ACO A;  2Z0V A;  3Q0K A;  4DYL A;  3QE6 A;  2RAI A;  2YKT A;  2Z0N A;  4AVM A;  5C5B B;  2EFL A;  2V0O A;  3QNI A;  4FZS A;  2Z0O A;  5C5B A;  2Q13 A;  1ZWW A;  2FIC A;  4ATM A;  4I1Q A;  2RAK A;  1X04 A;  3M3W A;  3SOG A;  2C08 A; 
#chains in the Genus database with same CATH topology
 3D4Z A;  3B51 X;  4R5I A;  1I4D A;  3BVX A;  4JNF A;  3F7W A;  3VKH A;  4R5J A;  3O3N B;  1GN9 A;  3DDG A;  4M0M A;  3DX4 A;  3OK8 A;  2WIN M;  2F1B A;  3RPM A;  2PY6 A;  3EJU A;  1TQW A;  2OZN B;  4EZZ A;  3ZED A;  2N3K A;  1LQ7 A;  1E9V A;  4H8S A;  4EZO A;  4EZS A;  1YWM A;  2OW7 A;  3A98 A;  1I49 A;  2FYV A;  1Y2O A;  3HAJ A;  3FD9 A;  3L3O M;  3CZN A;  3VEA A;  2YLL A;  4NPH A;  3BVU A;  1OA1 A;  2EX3 B;  2F7R A;  2YI8 A;  4PO2 A;  4JWD A;  1E2U A;  3SYV A;  3EJR A;  1W9M A;  2OBM A;  5TKY A;  2QXL A;  4JN4 A;  2F7P A;  4EZP A;  5C5B B;  1QWU A;  4HR1 A;  2ALW A;  2JNS A;  3D51 A;  2WYI A;  2Q12 A;  3KAV A;  3I04 A;  2GA9 D;  3HAH A;  4KIK B;  4AZ6 A;  2GAF D;  3RV0 A;  4EZV A;  4E3C A;  4IWP A;  3DX0 A;  3LMF A;  4IM3 A;  3DX1 A;  3EJS A;  3SOG A;  4JL9 A;  3CV5 A;  2LXY A;  1WDZ A;  3T46 A;  1DKX A;  2OBL A;  3EJT A;  1UPX A;  4BNE A;  4UDY X;  3QE6 A;  3ERC C;  4JLC A;  3QNI A;  3D2E A;  2ND0 A;  4I1Q A;  4EZU A;  1R33 A;  2F7Q A;  2OO2 A;  1OAO A;  5FIG A;  4HY9 A;  3B52 X;  3QA8 A;  2D1L A;  5E84 A;  3D52 A;  1DKY A;  3T47 A;  2OW6 A;  4R5L A;  2Q13 A;  1DKZ A;  3DDF A;  2YL9 A;  3LLL A;  1SU6 A;  4NSW A;  2KHO A;  4G6Q A;  3HAI A;  3KAW A;  4JWI A;  4AZI A;  2F1A A;  4DYL A;  2YKT A;  4AZC B;  4FZO A;  5C5B A;  4H6I A;  1GNL A;  4WPC A;  3I01 A;  4IWO A;  1SUF A;  4IW0 A;  1R5E A;  3T48 A;  2ELB A;  4KIK A;  2QFF A;  3BUD A;  2EWF A;  4ATM A;  1X04 A;  3DX2 A;  3UIT A;  1X03 A;  1R34 A;  3QNJ A;  2X3V A;  3DPQ A;  2RAJ A;  3BVT A;  3RV1 A;  3T49 A;  3B53 X;  3D50 A;  3ER9 B;  2Z8Y A;  1URU A;  4R5G A;  1MJG A;  3OHX M;  3BUP A;  3D2F A;  3BVW A;  4JWE A;  1QX1 A;  3BVV A;  1O7D B;  2WYH A;  2Z0N A;  4FZP A;  2YI9 A;  3EJP A;  2MI7 A;  3I39 X;  4WPE A;  2C08 A;  1HXK A;  3BUI A;  3D4Y A;  1TQT A;  1I4T A;  3PLT A;  1U00 A;  3CAZ A;  1ZYL A;  3G9G A;  1SU7 A;  3DX3 A;  4AZB A;  4AZG A;  4EZT A;  4EZX A;  4IM0 A;  5FLE X;  1E1D A;  4AZC A;  4H6H A;  2YL5 A;  3VEB A;  1TQU A;  3ABH A;  3T4A G;  4EZY A;  2PMR A;  3BUB A;  4EZN A;  1I4L A;  1TQS A;  3I2W A;  4EZQ A;  4B9Q A;  1JQK A;  3EJQ A;  2V0O A;  4R5K A;  1ZWW A;  2YIA A;  3M3W A;  4IM2 A;  2NCZ A;  2GF4 A;  3OWG A;  4D8J A;  2ND1 A;  2F7O A;  4JNE A;  4EZR A;  3C7N A;  4EZW A;  2Z0V A;  3Q0K A;  2X5C A;  2F18 A;  2RAI A;  4F01 A;  2YL6 A;  3BUQ A;  3LVT A;  4E81 A;  3DYT A;  5KBP A;  4AZ7 A;  3O3O B;  3BLB A;  3CVR A;  3QWE A;  3Q84 A;  1TQV A;  2RT6 A;  4AZ5 A;  4IWQ A;  2LM0 A;  3ACO A;  4AVM A;  2Z0O A;  1HWW A;  3CKD A;  1SU8 A;  4FM3 A;  4DCN C;  2YL8 A;  2QKW A;  4AZH A;  2D4C A;  4AKV A;  4NQI A;  3KDR A;  3DPP A;  2X3W A;  3CZS A;  2ZXQ A;  1O7D C;  4HR1 B;  4FZS A;  3DPO A;  2FIC A;  3L3P A;  1PS3 A;  3GI7 A;  2JNK A;  2EFK A;  4HYB A;  3O3M B;  2O0I 1;  2YIV X;  2X3X A;  2YIB A;  1OA0 A;  1GNT A;  4JWC A;  3ER8 C;  1HTY A;  4F00 A;  1QWN A;  2EFL A;  4UDX X;  2YLA A;  2RAK A; 
#chains in the Genus database with same CATH homology
 4DCN C;  3DYT A;  3SYV A;  1URU A;  2Q12 A;  1I4D A;  2EFK A;  1WDZ A;  3ABH A;  4WPE A;  1I4T A;  1X03 A;  3LLL A;  3PLT A;  3CAZ A;  4H8S A;  4NSW A;  4WPC A;  2D4C A;  4AKV A;  3QWE A;  3Q84 A;  4NQI A;  1I49 A;  1I4L A;  2X3X A;  3HAH A;  3I2W A;  3G9G A;  2ELB A;  1Y2O A;  2D1L A;  3HAI A;  3HAJ A;  2X3V A;  4BNE A;  2RAJ A;  2X3W A;  3OK8 A;  3ACO A;  2Z0V A;  3Q0K A;  4DYL A;  3QE6 A;  2RAI A;  2YKT A;  2Z0N A;  4AVM A;  5C5B B;  2EFL A;  2V0O A;  3QNI A;  4FZS A;  2Z0O A;  5C5B A;  2Q13 A;  1ZWW A;  2FIC A;  4ATM A;  4I1Q A;  2RAK A;  1X04 A;  3M3W A;  3SOG A;  2C08 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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