1COEA

Solution conformation of cobrotoxin: a nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing study
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
62
structure length
62
Chain Sequence
LECHNQQSSQTPTTTGCSGGETNCYKKRWRDHRGYRTERGCGCPSVKNGIEINCCTTDRCNN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution conformation of cobrotoxin: a nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing study.
pubmed doi rcsb
molecule tags Short neurotoxin
source organism Naja atra
molecule keywords COBROTOXIN
total genus 5
structure length 62
sequence length 62
ec nomenclature
pdb deposition date 1994-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00087 Toxin_TOLIP Snake toxin and toxin-like protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 1coeA00
2PJYB 2UWRA 1FFJA 1RL5A 4QTIU 2H5FA 2CRTA 1CDSA 2MJYA 1CTXA 1NYSA 1KBSA 2QC1A 4OM5A 1FSSB 1NXBA 1G6MA 1HOYA 1QM7A 2BHIA 2H62C 4AEAA 2MJ0A 1CCQA 2MJ4A 4ZQYA 5DZ5A 2H7ZB 1MR6A 1V6PA 1LXHA 4UY2C 4P7UA 2ABXA 1XT3A 1PLOA 2X8BB 1IK8A 1TXAA 2QJ9C 1CHVS 1FF4A 6EBXA 1S4YA 1CREA 2L03A 4OM4A 2UX2A 1REWC 5IMYC 2OFSA 3QB4B 1IDHA 1IKCA 2H8UA 1FSCA 3FEVA 2BTXA 3KFDE 1QKEA 1RGJA 1CDTA 3KFDI 2QJAC 2MUPA 2JVEA 2L5SA 2FD6U 1CODA 1ZADA 1M9ZA 1TGXA 2HLRA 1LSIA 1CVOA 1CB9A 1KXIA 5IMTD 4RUDA 1ERAA 2CCXA 1ES7B 4IYEA 3NDSA 2VLWA 1HC9A 1W6BA 1NORA 3ERAA 1ERGA 4FAOE 1IJCA 1F8UB 1KBAA 1KC4A 2QJBC 1NEAA 2H64C 1VB0A 2MHYA 1KU6B 3PLCA 1CXNA 4LFTA 1TFSA 1CRFA 1JBDA 1FASA 1LX5B 3EVSC 1IDGA 1COEA 3VTSA 1CDQA 2MUOA 4FAOC 2J8BA 1IDIA 1ABTA 1FRAA 4EY8B 5EBXA 2N99A 3U74U 2LCRA 1H0JA 1NTXA 4DO8A 2MFAA 2LA1A 5DU1A 1L4WA 3HH7A 2HLQA 3BT1U 2GOOC 3EBXA 4XJJA 2I9BE 1KTZB 2H64B 2CTXA 1BXPA 1DRSA 2NBTA 1KFHA 2K3GA 2H62D 3BT2U 3NH7A 2PJYC 4BIKB 1KL8A 5DO6A 1HAAA 1LXGA 1NTNA 2CRSA 2H7ZA 1B41B 2JQPA 1HC9B 1QKDA 1JE9A 1KBTA 1CXOA 3LAQU 1IDLA 1F94A 1CDRA 1TXBA 1I02A 1YWHA 2GOOB 1BTEA 3U73U 3NEQA 4HQPF 1KS6A 1LJZA 1MAHF 1NYUA 1IQ9A 4BDTB 1UG4A 1HAJA 1JGKA 2CDXA 2ERAA 1ONJA
chains in the Genus database with same CATH superfamily
2PJYB 2UWRA 1FFJA 1RL5A 4QTIU 2H5FA 2CRTA 1CDSA 2MJYA 1CTXA 1NYSA 1KBSA 2QC1A 4OM5A 1FSSB 1NXBA 1G6MA 1HOYA 1QM7A 2BHIA 2H62C 4AEAA 2MJ0A 1CCQA 2MJ4A 4ZQYA 5DZ5A 2H7ZB 1MR6A 1V6PA 1LXHA 4UY2C 4P7UA 2ABXA 1XT3A 1PLOA 2X8BB 1IK8A 1TXAA 2QJ9C 1CHVS 1FF4A 6EBXA 1S4YA 1CREA 2L03A 4OM4A 2UX2A 1REWC 5IMYC 2OFSA 3QB4B 1IDHA 1IKCA 2H8UA 1FSCA 3FEVA 2BTXA 3KFDE 4KSNA 1QKEA 1RGJA 1CDTA 3KFDI 2QJAC 2MUPA 2JVEA 2L5SA 2FD6U 1CODA 1ZADA 1M9ZA 1TGXA 2HLRA 1LSIA 1CVOA 1CB9A 1KXIA 5IMTD 4RUDA 1ERAA 2CCXA 1ES7B 4IYEA 3NDSA 2VLWA 1HC9A 1W6BA 1NORA 3ERAA 1ERGA 4FAOE 1IJCA 1F8UB 1KBAA 1KC4A 2QJBC 1NEAA 2H64C 1VB0A 2MHYA 1KU6B 3PLCA 1CXNA 4LFTA 1TFSA 1CRFA 1JBDA 1FASA 1LX5B 3EVSC 1IDGA 1COEA 3VTSA 1CDQA 2MUOA 4FAOC 2J8BA 1IDIA 1ABTA 1FRAA 4EY8B 5EBXA 2N99A 3U74U 2LCRA 1H0JA 1NTXA 4DO8A 2MFAA 2LA1A 5DU1A 1L4WA 3HH7A 2HLQA 3BT1U 2GOOC 3EBXA 4XJJA 2I9BE 1KTZB 2H64B 2CTXA 1BXPA 1DRSA 2NBTA 1KFHA 2K3GA 2H62D 3BT2U 3NH7A 2PJYC 4BIKB 1KL8A 5DO6A 1HAAA 1LXGA 1NTNA 2CRSA 2H7ZA 1B41B 2JQPA 1HC9B 1QKDA 1JE9A 1KBTA 1CXOA 3LAQU 1IDLA 1F94A 1CDRA 1TXBA 1I02A 1YWHA 2GOOB 1BTEA 3U73U 3NEQA 4HQPF 1KS6A 1LJZA 1MAHF 1NYUA 1IQ9A 4BDTB 1UG4A 1HAJA 1JGKA 2CDXA 2ERAA 1ONJA
chains in the Genus database with same CATH topology
2PJYB 2UWRA 1FFJA 1RL5A 4QTIU 2H5FA 2CRTA 1CDSA 2MJYA 1CTXA 1NYSA 1KBSA 2QC1A 4OM5A 1FSSB 1NXBA 1G6MA 1HOYA 1QM7A 2BHIA 2H62C 4AEAA 2MJ0A 1CCQA 2MJ4A 4ZQYA 5DZ5A 2H7ZB 1MR6A 1V6PA 1LXHA 4UY2C 4P7UA 2ABXA 1XT3A 1PLOA 2X8BB 1IK8A 1TXAA 2QJ9C 1CHVS 1FF4A 6EBXA 1S4YA 1CREA 2L03A 4OM4A 2UX2A 1REWC 5IMYC 2OFSA 3QB4B 1IDHA 1IKCA 2H8UA 1FSCA 3FEVA 2BTXA 3KFDE 4KSNA 1QKEA 1RGJA 1CDTA 3KFDI 2QJAC 2MUPA 2JVEA 2L5SA 2FD6U 1CODA 1ZADA 1M9ZA 1TGXA 2HLRA 1LSIA 1CVOA 1CB9A 1KXIA 5IMTD 4RUDA 1ERAA 2CCXA 1ES7B 4IYEA 3NDSA 2VLWA 1HC9A 1W6BA 1NORA 3ERAA 1ERGA 4FAOE 1IJCA 1F8UB 1KBAA 1KC4A 2QJBC 1NEAA 2H64C 1VB0A 2MHYA 1KU6B 3PLCA 1CXNA 4LFTA 1TFSA 1CRFA 1JBDA 1FASA 1LX5B 3EVSC 1IDGA 1COEA 3VTSA 1CDQA 2MUOA 4FAOC 2J8BA 1IDIA 1ABTA 1FRAA 4EY8B 5EBXA 2N99A 3U74U 2LCRA 1H0JA 1NTXA 4DO8A 2MFAA 2LA1A 5DU1A 1L4WA 3HH7A 2HLQA 3BT1U 2GOOC 3EBXA 4XJJA 2I9BE 1KTZB 2H64B 2CTXA 1BXPA 1DRSA 2NBTA 1KFHA 2K3GA 2H62D 3BT2U 3NH7A 2PJYC 4BIKB 1KL8A 5DO6A 1HAAA 1LXGA 1NTNA 2CRSA 2H7ZA 1B41B 2JQPA 1HC9B 1QKDA 1JE9A 1KBTA 1CXOA 3LAQU 1IDLA 1F94A 1CDRA 1TXBA 1I02A 1YWHA 2GOOB 1BTEA 3U73U 3NEQA 4HQPF 1KS6A 1LJZA 1MAHF 1NYUA 1IQ9A 4BDTB 1UG4A 1HAJA 1JGKA 2CDXA 2ERAA 1ONJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PJY B;  2UWR A;  1FFJ A;  1RL5 A;  4QTI U;  2H5F A;  2CRT A;  1CDS A;  2MJY A;  1CTX A;  1NYS A;  1KBS A;  2QC1 A;  4OM5 A;  1FSS B;  1NXB A;  1G6M A;  1HOY A;  1QM7 A;  2BHI A;  2H62 C;  4AEA A;  2MJ0 A;  1CCQ A;  2MJ4 A;  4ZQY A;  5DZ5 A;  2H7Z B;  1MR6 A;  1V6P A;  1LXH A;  4UY2 C;  4P7U A;  2ABX A;  1XT3 A;  1PLO A;  2X8B B;  1IK8 A;  1TXA A;  2QJ9 C;  1CHV S;  1FF4 A;  6EBX A;  1S4Y A;  1CRE A;  2L03 A;  4OM4 A;  2UX2 A;  1REW C;  5IMY C;  2OFS A;  3QB4 B;  1IDH A;  1IKC A;  2H8U A;  1FSC A;  3FEV A;  2BTX A;  3KFD E;  1QKE A;  1RGJ A;  1CDT A;  3KFD I;  2QJA C;  2MUP A;  2JVE A;  2L5S A;  2FD6 U;  1COD A;  1ZAD A;  1M9Z A;  1TGX A;  2HLR A;  1LSI A;  1CVO A;  1CB9 A;  1KXI A;  5IMT D;  4RUD A;  1ERA A;  2CCX A;  1ES7 B;  4IYE A;  3NDS A;  2VLW A;  1HC9 A;  1W6B A;  1NOR A;  3ERA A;  1ERG A;  4FAO E;  1IJC A;  1F8U B;  1KBA A;  1KC4 A;  2QJB C;  1NEA A;  2H64 C;  1VB0 A;  2MHY A;  1KU6 B;  3PLC A;  1CXN A;  4LFT A;  1TFS A;  1CRF A;  1JBD A;  1FAS A;  1LX5 B;  3EVS C;  1IDG A;  1COE A;  3VTS A;  1CDQ A;  2MUO A;  4FAO C;  2J8B A;  1IDI A;  1ABT A;  1FRA A;  4EY8 B;  5EBX A;  2N99 A;  3U74 U;  2LCR A;  1H0J A;  1NTX A;  4DO8 A;  2MFA A;  2LA1 A;  5DU1 A;  1L4W A;  3HH7 A;  2HLQ A;  3BT1 U;  2GOO C;  3EBX A;  4XJJ A;  2I9B E;  1KTZ B;  2H64 B;  2CTX A;  1BXP A;  1DRS A;  2NBT A;  1KFH A;  2K3G A;  2H62 D;  3BT2 U;  3NH7 A;  2PJY C;  4BIK B;  1KL8 A;  5DO6 A;  1HAA A;  1LXG A;  1NTN A;  2CRS A;  2H7Z A;  1B41 B;  2JQP A;  1HC9 B;  1QKD A;  1JE9 A;  1KBT A;  1CXO A;  3LAQ U;  1IDL A;  1F94 A;  1CDR A;  1TXB A;  1I02 A;  1YWH A;  2GOO B;  1BTE A;  3U73 U;  3NEQ A;  4HQP F;  1KS6 A;  1LJZ A;  1MAH F;  1NYU A;  1IQ9 A;  4BDT B;  1UG4 A;  1HAJ A;  1JGK A;  2CDX A;  2ERA A;  1ONJ A; 
#chains in the Genus database with same CATH topology
 2PJY B;  2UWR A;  1FFJ A;  1RL5 A;  4QTI U;  2H5F A;  2CRT A;  1CDS A;  2MJY A;  1CTX A;  1NYS A;  1KBS A;  2QC1 A;  4OM5 A;  1FSS B;  1NXB A;  1G6M A;  1HOY A;  1QM7 A;  2BHI A;  2H62 C;  4AEA A;  2MJ0 A;  1CCQ A;  2MJ4 A;  4ZQY A;  5DZ5 A;  2H7Z B;  1MR6 A;  1V6P A;  1LXH A;  4UY2 C;  4P7U A;  2ABX A;  1XT3 A;  1PLO A;  2X8B B;  1IK8 A;  1TXA A;  2QJ9 C;  1CHV S;  1FF4 A;  6EBX A;  1S4Y A;  1CRE A;  2L03 A;  4OM4 A;  2UX2 A;  1REW C;  5IMY C;  2OFS A;  3QB4 B;  1IDH A;  1IKC A;  2H8U A;  1FSC A;  3FEV A;  2BTX A;  3KFD E;  4KSN A;  1QKE A;  1RGJ A;  1CDT A;  3KFD I;  2QJA C;  2MUP A;  2JVE A;  2L5S A;  2FD6 U;  1COD A;  1ZAD A;  1M9Z A;  1TGX A;  2HLR A;  1LSI A;  1CVO A;  1CB9 A;  1KXI A;  5IMT D;  4RUD A;  1ERA A;  2CCX A;  1ES7 B;  4IYE A;  3NDS A;  2VLW A;  1HC9 A;  1W6B A;  1NOR A;  3ERA A;  1ERG A;  4FAO E;  1IJC A;  1F8U B;  1KBA A;  1KC4 A;  2QJB C;  1NEA A;  2H64 C;  1VB0 A;  2MHY A;  1KU6 B;  3PLC A;  1CXN A;  4LFT A;  1TFS A;  1CRF A;  1JBD A;  1FAS A;  1LX5 B;  3EVS C;  1IDG A;  1COE A;  3VTS A;  1CDQ A;  2MUO A;  4FAO C;  2J8B A;  1IDI A;  1ABT A;  1FRA A;  4EY8 B;  5EBX A;  2N99 A;  3U74 U;  2LCR A;  1H0J A;  1NTX A;  4DO8 A;  2MFA A;  2LA1 A;  5DU1 A;  1L4W A;  3HH7 A;  2HLQ A;  3BT1 U;  2GOO C;  3EBX A;  4XJJ A;  2I9B E;  1KTZ B;  2H64 B;  2CTX A;  1BXP A;  1DRS A;  2NBT A;  1KFH A;  2K3G A;  2H62 D;  3BT2 U;  3NH7 A;  2PJY C;  4BIK B;  1KL8 A;  5DO6 A;  1HAA A;  1LXG A;  1NTN A;  2CRS A;  2H7Z A;  1B41 B;  2JQP A;  1HC9 B;  1QKD A;  1JE9 A;  1KBT A;  1CXO A;  3LAQ U;  1IDL A;  1F94 A;  1CDR A;  1TXB A;  1I02 A;  1YWH A;  2GOO B;  1BTE A;  3U73 U;  3NEQ A;  4HQP F;  1KS6 A;  1LJZ A;  1MAH F;  1NYU A;  1IQ9 A;  4BDT B;  1UG4 A;  1HAJ A;  1JGK A;  2CDX A;  2ERA A;  1ONJ A; 
#chains in the Genus database with same CATH homology
 2PJY B;  2UWR A;  1FFJ A;  1RL5 A;  4QTI U;  2H5F A;  2CRT A;  1CDS A;  2MJY A;  1CTX A;  1NYS A;  1KBS A;  2QC1 A;  4OM5 A;  1FSS B;  1NXB A;  1G6M A;  1HOY A;  1QM7 A;  2BHI A;  2H62 C;  4AEA A;  2MJ0 A;  1CCQ A;  2MJ4 A;  4ZQY A;  5DZ5 A;  2H7Z B;  1MR6 A;  1V6P A;  1LXH A;  4UY2 C;  4P7U A;  2ABX A;  1XT3 A;  1PLO A;  2X8B B;  1IK8 A;  1TXA A;  2QJ9 C;  1CHV S;  1FF4 A;  6EBX A;  1S4Y A;  1CRE A;  2L03 A;  4OM4 A;  2UX2 A;  1REW C;  5IMY C;  2OFS A;  3QB4 B;  1IDH A;  1IKC A;  2H8U A;  1FSC A;  3FEV A;  2BTX A;  3KFD E;  4KSN A;  1QKE A;  1RGJ A;  1CDT A;  3KFD I;  2QJA C;  2MUP A;  2JVE A;  2L5S A;  2FD6 U;  1COD A;  1ZAD A;  1M9Z A;  1TGX A;  2HLR A;  1LSI A;  1CVO A;  1CB9 A;  1KXI A;  5IMT D;  4RUD A;  1ERA A;  2CCX A;  1ES7 B;  4IYE A;  3NDS A;  2VLW A;  1HC9 A;  1W6B A;  1NOR A;  3ERA A;  1ERG A;  4FAO E;  1IJC A;  1F8U B;  1KBA A;  1KC4 A;  2QJB C;  1NEA A;  2H64 C;  1VB0 A;  2MHY A;  1KU6 B;  3PLC A;  1CXN A;  4LFT A;  1TFS A;  1CRF A;  1JBD A;  1FAS A;  1LX5 B;  3EVS C;  1IDG A;  1COE A;  3VTS A;  1CDQ A;  2MUO A;  4FAO C;  2J8B A;  1IDI A;  1ABT A;  1FRA A;  4EY8 B;  5EBX A;  2N99 A;  3U74 U;  2LCR A;  1H0J A;  1NTX A;  4DO8 A;  2MFA A;  2LA1 A;  5DU1 A;  1L4W A;  3HH7 A;  2HLQ A;  3BT1 U;  2GOO C;  3EBX A;  4XJJ A;  2I9B E;  1KTZ B;  2H64 B;  2CTX A;  1BXP A;  1DRS A;  2NBT A;  1KFH A;  2K3G A;  2H62 D;  3BT2 U;  3NH7 A;  2PJY C;  4BIK B;  1KL8 A;  5DO6 A;  1HAA A;  1LXG A;  1NTN A;  2CRS A;  2H7Z A;  1B41 B;  2JQP A;  1HC9 B;  1QKD A;  1JE9 A;  1KBT A;  1CXO A;  3LAQ U;  1IDL A;  1F94 A;  1CDR A;  1TXB A;  1I02 A;  1YWH A;  2GOO B;  1BTE A;  3U73 U;  3NEQ A;  4HQP F;  1KS6 A;  1LJZ A;  1MAH F;  1NYU A;  1IQ9 A;  4BDT B;  1UG4 A;  1HAJ A;  1JGK A;  2CDX A;  2ERA A;  1ONJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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