1KS6A

Transforming growth factor beta type ii receptor ligand binding domain
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
107
structure length
107
Chain Sequence
QLPRLCKFCDVKATTCSNQDQCTSNCNITSICEKNNEVCAAVWRRNDENVTLETICHDPQKRLYGHMLDDSSSEQCVMKEKKDDGGLMFMCSCTGEECNDVLIFSAI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the chick TGFb type II receptor ligand binding domain
pubmed doi rcsb
molecule tags Hormone/growth factor
source organism Gallus gallus
molecule keywords TRANSFORMING GROWTH FACTOR BETA TYPE II RECEPTOR
total genus 10
structure length 107
sequence length 107
ec nomenclature ec 2.7.11.30: Receptor protein serine/threonine kinase.
pdb deposition date 2002-01-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 1ks6A00
5IMYC 1KL8A 1NYSA 4FAOE 1ONJA 2H8UA 2QC1A 1KS6A 1CXOA 2NBTA 1CVOA 1LXGA 1F8UB 1QKEA 2H62C 2ERAA 1V6PA 2CDXA 1HC9B 1CDRA 5IMTD 2GOOB 3LAQU 1L4WA 2MJ0A 1CDSA 5DO6A 1CODA 4BIKB 1QKDA 2J8BA 5DU1A 2BTXA 1KC4A 3EBXA 1XT3A 2I9BE 2H5FA 2LA1A 1NTXA 2UX2A 3QB4B 4P7UA 1KBAA 2LCRA 1KFHA 1NYUA 1B41B 1CCQA 1MAHF 2H7ZB 4FAOC 1IDHA 2GOOC 1KU6B 4BDTB 4EY8B 1LX5B 3BT2U 1LJZA 1HOYA 2QJBC 1CDTA 1IDGA 1TXBA 2MUPA 2OFSA 1IDIA 2X8BB 3FEVA 1IK8A 3KFDI 2CCXA 3ERAA 1M9ZA 6EBXA 1KXIA 3NH7A 4UY2C 1W6BA 5DZ5A 1LSIA 2MHYA 2QJAC 1TXAA 1IQ9A 4XJJA 4DO8A 2N99A 1HC9A 1NEAA 1F94A 1RGJA 4IYEA 1S4YA 5EBXA 1JGKA 1IDLA 2HLQA 1CRFA 1FFJA 4LFTA 2MJYA 2K3GA 1IKCA 1H0JA 3NDSA 1JE9A 1ABTA 2L03A 1MR6A 1UG4A 2H7ZA 1QM7A 1CXNA 3KFDE 1HAAA 2JQPA 2MUOA 1ERAA 1YWHA 2ABXA 1FSSB 4RUDA 2CTXA 1FSCA 2H64B 4OM4A 2L5SA 2HLRA 2MJ4A 3HH7A 1FRAA 1BXPA 3NEQA 1JBDA 2CRTA 2PJYB 1ES7B 4QTIU 2UWRA 1COEA 1FF4A 1BTEA 1PLOA 3EVSC 3U74U 4AEAA 1DRSA 1KBSA 1KTZB 3BT1U 3U73U 1CREA 2CRSA 2H64C 4OM5A 2QJ9C 2JVEA 1FASA 1ERGA 2PJYC 1KBTA 3VTSA 2BHIA 2H62D 3PLCA 1TGXA 2FD6U 1G6MA 1IJCA 1REWC 1VB0A 1HAJA 1NORA 1CHVS 1I02A 1TFSA 4HQPF 1CDQA 1LXHA 1CB9A 1RL5A 1ZADA 4ZQYA 2MFAA 2VLWA 1NXBA 1CTXA 1NTNA
chains in the Genus database with same CATH superfamily
5IMYC 1KL8A 1NYSA 4FAOE 1ONJA 2H8UA 2QC1A 1KS6A 1CXOA 2NBTA 1CVOA 1LXGA 1F8UB 1QKEA 2H62C 2ERAA 1V6PA 2CDXA 1HC9B 1CDRA 5IMTD 2GOOB 3LAQU 1L4WA 2MJ0A 1CDSA 5DO6A 1CODA 4BIKB 1QKDA 2J8BA 5DU1A 2BTXA 1KC4A 3EBXA 1XT3A 2I9BE 2H5FA 2LA1A 1NTXA 2UX2A 3QB4B 4P7UA 1KBAA 2LCRA 1KFHA 1NYUA 1B41B 1CCQA 1MAHF 2H7ZB 4FAOC 1IDHA 2GOOC 1KU6B 4BDTB 4EY8B 1LX5B 3BT2U 1LJZA 1HOYA 2QJBC 1CDTA 1IDGA 1TXBA 2MUPA 2OFSA 1IDIA 2X8BB 3FEVA 1IK8A 3KFDI 2CCXA 3ERAA 1M9ZA 6EBXA 1KXIA 3NH7A 4UY2C 1W6BA 5DZ5A 4KSNA 1LSIA 2MHYA 2QJAC 1TXAA 1IQ9A 4XJJA 4DO8A 2N99A 1HC9A 1NEAA 1F94A 1RGJA 4IYEA 1S4YA 5EBXA 1JGKA 1IDLA 2HLQA 1CRFA 1FFJA 4LFTA 2MJYA 2K3GA 1IKCA 1H0JA 3NDSA 1JE9A 1ABTA 2L03A 1MR6A 1UG4A 2H7ZA 1QM7A 1CXNA 3KFDE 1HAAA 2JQPA 2MUOA 1ERAA 1YWHA 2ABXA 1FSSB 4RUDA 2CTXA 1FSCA 2H64B 4OM4A 2L5SA 2HLRA 2MJ4A 3HH7A 1FRAA 1BXPA 3NEQA 1JBDA 2CRTA 2PJYB 1ES7B 4QTIU 2UWRA 1COEA 1FF4A 1BTEA 1PLOA 3EVSC 3U74U 4AEAA 1DRSA 1KBSA 1KTZB 3BT1U 3U73U 1CREA 2CRSA 2H64C 4OM5A 2QJ9C 2JVEA 1FASA 1ERGA 2PJYC 1KBTA 3VTSA 2BHIA 2H62D 3PLCA 1TGXA 2FD6U 1G6MA 1IJCA 1REWC 1VB0A 1HAJA 1NORA 1CHVS 1I02A 1TFSA 4HQPF 1CDQA 1LXHA 1CB9A 1RL5A 1ZADA 4ZQYA 2MFAA 2VLWA 1NXBA 1CTXA 1NTNA
chains in the Genus database with same CATH topology
5IMYC 1KL8A 1NYSA 4FAOE 1ONJA 2H8UA 2QC1A 1KS6A 1CXOA 2NBTA 1CVOA 1LXGA 1F8UB 1QKEA 2H62C 2ERAA 1V6PA 2CDXA 1HC9B 1CDRA 5IMTD 2GOOB 3LAQU 1L4WA 2MJ0A 1CDSA 5DO6A 1CODA 4BIKB 1QKDA 2J8BA 5DU1A 2BTXA 1KC4A 3EBXA 1XT3A 2I9BE 2H5FA 2LA1A 1NTXA 2UX2A 3QB4B 4P7UA 1KBAA 2LCRA 1KFHA 1NYUA 1B41B 1CCQA 1MAHF 2H7ZB 4FAOC 1IDHA 2GOOC 1KU6B 4BDTB 4EY8B 1LX5B 3BT2U 1LJZA 1HOYA 2QJBC 1CDTA 1IDGA 1TXBA 2MUPA 2OFSA 1IDIA 2X8BB 3FEVA 1IK8A 3KFDI 2CCXA 3ERAA 1M9ZA 6EBXA 1KXIA 3NH7A 4UY2C 1W6BA 5DZ5A 4KSNA 1LSIA 2MHYA 2QJAC 1TXAA 1IQ9A 4XJJA 4DO8A 2N99A 1HC9A 1NEAA 1F94A 1RGJA 4IYEA 1S4YA 5EBXA 1JGKA 1IDLA 2HLQA 1CRFA 1FFJA 4LFTA 2MJYA 2K3GA 1IKCA 1H0JA 3NDSA 1JE9A 1ABTA 2L03A 1MR6A 1UG4A 2H7ZA 1QM7A 1CXNA 3KFDE 1HAAA 2JQPA 2MUOA 1ERAA 1YWHA 2ABXA 1FSSB 4RUDA 2CTXA 1FSCA 2H64B 4OM4A 2L5SA 2HLRA 2MJ4A 3HH7A 1FRAA 1BXPA 3NEQA 1JBDA 2CRTA 2PJYB 1ES7B 4QTIU 2UWRA 1COEA 1FF4A 1BTEA 1PLOA 3EVSC 3U74U 4AEAA 1DRSA 1KBSA 1KTZB 3BT1U 3U73U 1CREA 2CRSA 2H64C 4OM5A 2QJ9C 2JVEA 1FASA 1ERGA 2PJYC 1KBTA 3VTSA 2BHIA 2H62D 3PLCA 1TGXA 2FD6U 1G6MA 1IJCA 1REWC 1VB0A 1HAJA 1NORA 1CHVS 1I02A 1TFSA 4HQPF 1CDQA 1LXHA 1CB9A 1RL5A 1ZADA 4ZQYA 2MFAA 2VLWA 1NXBA 1CTXA 1NTNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IMY C;  1KL8 A;  1NYS A;  4FAO E;  1ONJ A;  2H8U A;  2QC1 A;  1KS6 A;  1CXO A;  2NBT A;  1CVO A;  1LXG A;  1F8U B;  1QKE A;  2H62 C;  2ERA A;  1V6P A;  2CDX A;  1HC9 B;  1CDR A;  5IMT D;  2GOO B;  3LAQ U;  1L4W A;  2MJ0 A;  1CDS A;  5DO6 A;  1COD A;  4BIK B;  1QKD A;  2J8B A;  5DU1 A;  2BTX A;  1KC4 A;  3EBX A;  1XT3 A;  2I9B E;  2H5F A;  2LA1 A;  1NTX A;  2UX2 A;  3QB4 B;  4P7U A;  1KBA A;  2LCR A;  1KFH A;  1NYU A;  1B41 B;  1CCQ A;  1MAH F;  2H7Z B;  4FAO C;  1IDH A;  2GOO C;  1KU6 B;  4BDT B;  4EY8 B;  1LX5 B;  3BT2 U;  1LJZ A;  1HOY A;  2QJB C;  1CDT A;  1IDG A;  1TXB A;  2MUP A;  2OFS A;  1IDI A;  2X8B B;  3FEV A;  1IK8 A;  3KFD I;  2CCX A;  3ERA A;  1M9Z A;  6EBX A;  1KXI A;  3NH7 A;  4UY2 C;  1W6B A;  5DZ5 A;  1LSI A;  2MHY A;  2QJA C;  1TXA A;  1IQ9 A;  4XJJ A;  4DO8 A;  2N99 A;  1HC9 A;  1NEA A;  1F94 A;  1RGJ A;  4IYE A;  1S4Y A;  5EBX A;  1JGK A;  1IDL A;  2HLQ A;  1CRF A;  1FFJ A;  4LFT A;  2MJY A;  2K3G A;  1IKC A;  1H0J A;  3NDS A;  1JE9 A;  1ABT A;  2L03 A;  1MR6 A;  1UG4 A;  2H7Z A;  1QM7 A;  1CXN A;  3KFD E;  1HAA A;  2JQP A;  2MUO A;  1ERA A;  1YWH A;  2ABX A;  1FSS B;  4RUD A;  2CTX A;  1FSC A;  2H64 B;  4OM4 A;  2L5S A;  2HLR A;  2MJ4 A;  3HH7 A;  1FRA A;  1BXP A;  3NEQ A;  1JBD A;  2CRT A;  2PJY B;  1ES7 B;  4QTI U;  2UWR A;  1COE A;  1FF4 A;  1BTE A;  1PLO A;  3EVS C;  3U74 U;  4AEA A;  1DRS A;  1KBS A;  1KTZ B;  3BT1 U;  3U73 U;  1CRE A;  2CRS A;  2H64 C;  4OM5 A;  2QJ9 C;  2JVE A;  1FAS A;  1ERG A;  2PJY C;  1KBT A;  3VTS A;  2BHI A;  2H62 D;  3PLC A;  1TGX A;  2FD6 U;  1G6M A;  1IJC A;  1REW C;  1VB0 A;  1HAJ A;  1NOR A;  1CHV S;  1I02 A;  1TFS A;  4HQP F;  1CDQ A;  1LXH A;  1CB9 A;  1RL5 A;  1ZAD A;  4ZQY A;  2MFA A;  2VLW A;  1NXB A;  1CTX A;  1NTN A; 
#chains in the Genus database with same CATH topology
 5IMY C;  1KL8 A;  1NYS A;  4FAO E;  1ONJ A;  2H8U A;  2QC1 A;  1KS6 A;  1CXO A;  2NBT A;  1CVO A;  1LXG A;  1F8U B;  1QKE A;  2H62 C;  2ERA A;  1V6P A;  2CDX A;  1HC9 B;  1CDR A;  5IMT D;  2GOO B;  3LAQ U;  1L4W A;  2MJ0 A;  1CDS A;  5DO6 A;  1COD A;  4BIK B;  1QKD A;  2J8B A;  5DU1 A;  2BTX A;  1KC4 A;  3EBX A;  1XT3 A;  2I9B E;  2H5F A;  2LA1 A;  1NTX A;  2UX2 A;  3QB4 B;  4P7U A;  1KBA A;  2LCR A;  1KFH A;  1NYU A;  1B41 B;  1CCQ A;  1MAH F;  2H7Z B;  4FAO C;  1IDH A;  2GOO C;  1KU6 B;  4BDT B;  4EY8 B;  1LX5 B;  3BT2 U;  1LJZ A;  1HOY A;  2QJB C;  1CDT A;  1IDG A;  1TXB A;  2MUP A;  2OFS A;  1IDI A;  2X8B B;  3FEV A;  1IK8 A;  3KFD I;  2CCX A;  3ERA A;  1M9Z A;  6EBX A;  1KXI A;  3NH7 A;  4UY2 C;  1W6B A;  5DZ5 A;  4KSN A;  1LSI A;  2MHY A;  2QJA C;  1TXA A;  1IQ9 A;  4XJJ A;  4DO8 A;  2N99 A;  1HC9 A;  1NEA A;  1F94 A;  1RGJ A;  4IYE A;  1S4Y A;  5EBX A;  1JGK A;  1IDL A;  2HLQ A;  1CRF A;  1FFJ A;  4LFT A;  2MJY A;  2K3G A;  1IKC A;  1H0J A;  3NDS A;  1JE9 A;  1ABT A;  2L03 A;  1MR6 A;  1UG4 A;  2H7Z A;  1QM7 A;  1CXN A;  3KFD E;  1HAA A;  2JQP A;  2MUO A;  1ERA A;  1YWH A;  2ABX A;  1FSS B;  4RUD A;  2CTX A;  1FSC A;  2H64 B;  4OM4 A;  2L5S A;  2HLR A;  2MJ4 A;  3HH7 A;  1FRA A;  1BXP A;  3NEQ A;  1JBD A;  2CRT A;  2PJY B;  1ES7 B;  4QTI U;  2UWR A;  1COE A;  1FF4 A;  1BTE A;  1PLO A;  3EVS C;  3U74 U;  4AEA A;  1DRS A;  1KBS A;  1KTZ B;  3BT1 U;  3U73 U;  1CRE A;  2CRS A;  2H64 C;  4OM5 A;  2QJ9 C;  2JVE A;  1FAS A;  1ERG A;  2PJY C;  1KBT A;  3VTS A;  2BHI A;  2H62 D;  3PLC A;  1TGX A;  2FD6 U;  1G6M A;  1IJC A;  1REW C;  1VB0 A;  1HAJ A;  1NOR A;  1CHV S;  1I02 A;  1TFS A;  4HQP F;  1CDQ A;  1LXH A;  1CB9 A;  1RL5 A;  1ZAD A;  4ZQY A;  2MFA A;  2VLW A;  1NXB A;  1CTX A;  1NTN A; 
#chains in the Genus database with same CATH homology
 5IMY C;  1KL8 A;  1NYS A;  4FAO E;  1ONJ A;  2H8U A;  2QC1 A;  1KS6 A;  1CXO A;  2NBT A;  1CVO A;  1LXG A;  1F8U B;  1QKE A;  2H62 C;  2ERA A;  1V6P A;  2CDX A;  1HC9 B;  1CDR A;  5IMT D;  2GOO B;  3LAQ U;  1L4W A;  2MJ0 A;  1CDS A;  5DO6 A;  1COD A;  4BIK B;  1QKD A;  2J8B A;  5DU1 A;  2BTX A;  1KC4 A;  3EBX A;  1XT3 A;  2I9B E;  2H5F A;  2LA1 A;  1NTX A;  2UX2 A;  3QB4 B;  4P7U A;  1KBA A;  2LCR A;  1KFH A;  1NYU A;  1B41 B;  1CCQ A;  1MAH F;  2H7Z B;  4FAO C;  1IDH A;  2GOO C;  1KU6 B;  4BDT B;  4EY8 B;  1LX5 B;  3BT2 U;  1LJZ A;  1HOY A;  2QJB C;  1CDT A;  1IDG A;  1TXB A;  2MUP A;  2OFS A;  1IDI A;  2X8B B;  3FEV A;  1IK8 A;  3KFD I;  2CCX A;  3ERA A;  1M9Z A;  6EBX A;  1KXI A;  3NH7 A;  4UY2 C;  1W6B A;  5DZ5 A;  4KSN A;  1LSI A;  2MHY A;  2QJA C;  1TXA A;  1IQ9 A;  4XJJ A;  4DO8 A;  2N99 A;  1HC9 A;  1NEA A;  1F94 A;  1RGJ A;  4IYE A;  1S4Y A;  5EBX A;  1JGK A;  1IDL A;  2HLQ A;  1CRF A;  1FFJ A;  4LFT A;  2MJY A;  2K3G A;  1IKC A;  1H0J A;  3NDS A;  1JE9 A;  1ABT A;  2L03 A;  1MR6 A;  1UG4 A;  2H7Z A;  1QM7 A;  1CXN A;  3KFD E;  1HAA A;  2JQP A;  2MUO A;  1ERA A;  1YWH A;  2ABX A;  1FSS B;  4RUD A;  2CTX A;  1FSC A;  2H64 B;  4OM4 A;  2L5S A;  2HLR A;  2MJ4 A;  3HH7 A;  1FRA A;  1BXP A;  3NEQ A;  1JBD A;  2CRT A;  2PJY B;  1ES7 B;  4QTI U;  2UWR A;  1COE A;  1FF4 A;  1BTE A;  1PLO A;  3EVS C;  3U74 U;  4AEA A;  1DRS A;  1KBS A;  1KTZ B;  3BT1 U;  3U73 U;  1CRE A;  2CRS A;  2H64 C;  4OM5 A;  2QJ9 C;  2JVE A;  1FAS A;  1ERG A;  2PJY C;  1KBT A;  3VTS A;  2BHI A;  2H62 D;  3PLC A;  1TGX A;  2FD6 U;  1G6M A;  1IJC A;  1REW C;  1VB0 A;  1HAJ A;  1NOR A;  1CHV S;  1I02 A;  1TFS A;  4HQP F;  1CDQ A;  1LXH A;  1CB9 A;  1RL5 A;  1ZAD A;  4ZQY A;  2MFA A;  2VLW A;  1NXB A;  1CTX A;  1NTN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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