3EVSC

Crystal structure of the gdf-5:bmp receptor ib complex.
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
85
structure length
85
Chain Sequence
ILRCKCHHHCPEDSVNNICSTDGYCFTMIEEDDSGMPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cytokine/transferase receptor
source organism Homo sapiens
publication title Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5-type I receptor specificity.
pubmed doi rcsb
molecule keywords Growth/differentiation factor 5
total genus 16
structure length 85
sequence length 85
ec nomenclature ec 2.7.11.30: Receptor protein serine/threonine kinase.
pdb deposition date 2008-10-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01064 Activin_recp Activin types I and II receptor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 3evsC00
2MUPA 2J8BA 1ONJA 1KBTA 1JE9A 1IKCA 1KTZB 3VTSA 5DO6A 1FSCA 2OFSA 2CDXA 1LSIA 1TFSA 1HAJA 1CTXA 1NXBA 1JBDA 2PJYB 4HQPF 2UX2A 1CREA 2JVEA 1W6BA 1CDTA 2H7ZA 4LFTA 4OM5A 5DZ5A 3FEVA 1CHVS 1NTXA 1IQ9A 2K3GA 1I02A 1TGXA 2H62C 2CRTA 1KXIA 2CRSA 4FAOE 1IK8A 1RL5A 2NBTA 3BT2U 4EY8B 4FAOC 3QB4B 1CDQA 4ZQYA 4DO8A 2MJ4A 2H7ZB 2UWRA 1JGKA 1LX5B 3HH7A 3LAQU 1IJCA 2H5FA 3KFDI 2ABXA 2ERAA 1FF4A 1F8UB 1L4WA 2HLRA 1HC9A 1G6MA 4OM4A 1TXBA 3EVSC 2MUOA 1ES7B 1ABTA 2MJYA 1KBSA 2X8BB 2MHYA 1FSSB 2MJ0A 4UY2C 4BDTB 3NEQA 2H8UA 3KFDE 1CXOA 1LXGA 3EBXA 2H62D 1NYSA 1F94A 1TXAA 2H64C 1FRAA 2BHIA 1MR6A 2CTXA 4IYEA 1M9ZA 2L03A 1CDSA 1KU6B 1CVOA 2LCRA 3U74U 5IMTD 1DRSA 1CCQA 3NH7A 4P7UA 4RUDA 1QKDA 1ERGA 4QTIU 1NORA 2GOOC 2N99A 2JQPA 1B41B 1S4YA 1ZADA 2VLWA 1KC4A 1PLOA 1CB9A 1HC9B 2L5SA 1BTEA 1KS6A 4BIKB 1KFHA 2MFAA 1YWHA 1NYUA 1BXPA 2HLQA 2H64B 1LJZA 4XJJA 1FASA 2LA1A 5DU1A 1REWC 1MAHF 1ERAA 5IMYC 1CXNA 1CODA 1CDRA 2I9BE 6EBXA 1CRFA 1LXHA 1IDHA 1FFJA 1KL8A 3ERAA 1VB0A 1KBAA 3BT1U 2QC1A 2GOOB 2QJBC 2PJYC 2QJAC 1NEAA 4AEAA 1QM7A 2BTXA 3NDSA 5EBXA 2QJ9C 2CCXA 1XT3A 1HAAA 1NTNA 3U73U 1IDGA 1QKEA 1HOYA 2FD6U 1V6PA 3PLCA 1COEA 1IDLA 1IDIA 1RGJA 1H0JA 1UG4A
chains in the Genus database with same CATH superfamily
2MUPA 2J8BA 1ONJA 1KBTA 1JE9A 1IKCA 1KTZB 3VTSA 5DO6A 1FSCA 2OFSA 2CDXA 1LSIA 1TFSA 1HAJA 1CTXA 1NXBA 1JBDA 2PJYB 4HQPF 2UX2A 1CREA 2JVEA 1W6BA 1CDTA 2H7ZA 4LFTA 4OM5A 5DZ5A 3FEVA 1CHVS 1NTXA 1IQ9A 2K3GA 1I02A 1TGXA 2H62C 2CRTA 1KXIA 2CRSA 4FAOE 1IK8A 1RL5A 2NBTA 3BT2U 4EY8B 4FAOC 3QB4B 1CDQA 4ZQYA 4DO8A 2MJ4A 2H7ZB 2UWRA 1JGKA 1LX5B 3HH7A 3LAQU 1IJCA 2H5FA 3KFDI 2ABXA 2ERAA 4KSNA 1FF4A 1F8UB 1L4WA 2HLRA 1HC9A 1G6MA 4OM4A 1TXBA 3EVSC 2MUOA 1ES7B 1ABTA 2MJYA 1KBSA 2X8BB 2MHYA 1FSSB 2MJ0A 4UY2C 4BDTB 3NEQA 2H8UA 3KFDE 1CXOA 1LXGA 3EBXA 2H62D 1NYSA 1F94A 1TXAA 2H64C 1FRAA 2BHIA 1MR6A 2CTXA 4IYEA 1M9ZA 2L03A 1CDSA 1KU6B 1CVOA 2LCRA 3U74U 5IMTD 1DRSA 1CCQA 3NH7A 4P7UA 4RUDA 1QKDA 1ERGA 4QTIU 1NORA 2GOOC 2N99A 2JQPA 1B41B 1S4YA 1ZADA 2VLWA 1KC4A 1PLOA 1CB9A 1HC9B 2L5SA 1BTEA 1KS6A 4BIKB 1KFHA 2MFAA 1YWHA 1NYUA 1BXPA 2HLQA 2H64B 1LJZA 4XJJA 1FASA 2LA1A 5DU1A 1REWC 1MAHF 1ERAA 5IMYC 1CXNA 1CODA 1CDRA 2I9BE 6EBXA 1CRFA 1LXHA 1IDHA 1FFJA 1KL8A 3ERAA 1VB0A 1KBAA 3BT1U 2QC1A 2GOOB 2QJBC 2PJYC 2QJAC 1NEAA 4AEAA 1QM7A 2BTXA 3NDSA 5EBXA 2QJ9C 2CCXA 1XT3A 1HAAA 1NTNA 3U73U 1IDGA 1QKEA 1HOYA 2FD6U 1V6PA 3PLCA 1COEA 1IDLA 1IDIA 1RGJA 1H0JA 1UG4A
chains in the Genus database with same CATH topology
2MUPA 2J8BA 1ONJA 1KBTA 1JE9A 1IKCA 1KTZB 3VTSA 5DO6A 1FSCA 2OFSA 2CDXA 1LSIA 1TFSA 1HAJA 1CTXA 1NXBA 1JBDA 2PJYB 4HQPF 2UX2A 1CREA 2JVEA 1W6BA 1CDTA 2H7ZA 4LFTA 4OM5A 5DZ5A 3FEVA 1CHVS 1NTXA 1IQ9A 2K3GA 1I02A 1TGXA 2H62C 2CRTA 1KXIA 2CRSA 4FAOE 1IK8A 1RL5A 2NBTA 3BT2U 4EY8B 4FAOC 3QB4B 1CDQA 4ZQYA 4DO8A 2MJ4A 2H7ZB 2UWRA 1JGKA 1LX5B 3HH7A 3LAQU 1IJCA 2H5FA 3KFDI 2ABXA 2ERAA 4KSNA 1FF4A 1F8UB 1L4WA 2HLRA 1HC9A 1G6MA 4OM4A 1TXBA 3EVSC 2MUOA 1ES7B 1ABTA 2MJYA 1KBSA 2X8BB 2MHYA 1FSSB 2MJ0A 4UY2C 4BDTB 3NEQA 2H8UA 3KFDE 1CXOA 1LXGA 3EBXA 2H62D 1NYSA 1F94A 1TXAA 2H64C 1FRAA 2BHIA 1MR6A 2CTXA 4IYEA 1M9ZA 2L03A 1CDSA 1KU6B 1CVOA 2LCRA 3U74U 5IMTD 1DRSA 1CCQA 3NH7A 4P7UA 4RUDA 1QKDA 1ERGA 4QTIU 1NORA 2GOOC 2N99A 2JQPA 1B41B 1S4YA 1ZADA 2VLWA 1KC4A 1PLOA 1CB9A 1HC9B 2L5SA 1BTEA 1KS6A 4BIKB 1KFHA 2MFAA 1YWHA 1NYUA 1BXPA 2HLQA 2H64B 1LJZA 4XJJA 1FASA 2LA1A 5DU1A 1REWC 1MAHF 1ERAA 5IMYC 1CXNA 1CODA 1CDRA 2I9BE 6EBXA 1CRFA 1LXHA 1IDHA 1FFJA 1KL8A 3ERAA 1VB0A 1KBAA 3BT1U 2QC1A 2GOOB 2QJBC 2PJYC 2QJAC 1NEAA 4AEAA 1QM7A 2BTXA 3NDSA 5EBXA 2QJ9C 2CCXA 1XT3A 1HAAA 1NTNA 3U73U 1IDGA 1QKEA 1HOYA 2FD6U 1V6PA 3PLCA 1COEA 1IDLA 1IDIA 1RGJA 1H0JA 1UG4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MUP A;  2J8B A;  1ONJ A;  1KBT A;  1JE9 A;  1IKC A;  1KTZ B;  3VTS A;  5DO6 A;  1FSC A;  2OFS A;  2CDX A;  1LSI A;  1TFS A;  1HAJ A;  1CTX A;  1NXB A;  1JBD A;  2PJY B;  4HQP F;  2UX2 A;  1CRE A;  2JVE A;  1W6B A;  1CDT A;  2H7Z A;  4LFT A;  4OM5 A;  5DZ5 A;  3FEV A;  1CHV S;  1NTX A;  1IQ9 A;  2K3G A;  1I02 A;  1TGX A;  2H62 C;  2CRT A;  1KXI A;  2CRS A;  4FAO E;  1IK8 A;  1RL5 A;  2NBT A;  3BT2 U;  4EY8 B;  4FAO C;  3QB4 B;  1CDQ A;  4ZQY A;  4DO8 A;  2MJ4 A;  2H7Z B;  2UWR A;  1JGK A;  1LX5 B;  3HH7 A;  3LAQ U;  1IJC A;  2H5F A;  3KFD I;  2ABX A;  2ERA A;  1FF4 A;  1F8U B;  1L4W A;  2HLR A;  1HC9 A;  1G6M A;  4OM4 A;  1TXB A;  3EVS C;  2MUO A;  1ES7 B;  1ABT A;  2MJY A;  1KBS A;  2X8B B;  2MHY A;  1FSS B;  2MJ0 A;  4UY2 C;  4BDT B;  3NEQ A;  2H8U A;  3KFD E;  1CXO A;  1LXG A;  3EBX A;  2H62 D;  1NYS A;  1F94 A;  1TXA A;  2H64 C;  1FRA A;  2BHI A;  1MR6 A;  2CTX A;  4IYE A;  1M9Z A;  2L03 A;  1CDS A;  1KU6 B;  1CVO A;  2LCR A;  3U74 U;  5IMT D;  1DRS A;  1CCQ A;  3NH7 A;  4P7U A;  4RUD A;  1QKD A;  1ERG A;  4QTI U;  1NOR A;  2GOO C;  2N99 A;  2JQP A;  1B41 B;  1S4Y A;  1ZAD A;  2VLW A;  1KC4 A;  1PLO A;  1CB9 A;  1HC9 B;  2L5S A;  1BTE A;  1KS6 A;  4BIK B;  1KFH A;  2MFA A;  1YWH A;  1NYU A;  1BXP A;  2HLQ A;  2H64 B;  1LJZ A;  4XJJ A;  1FAS A;  2LA1 A;  5DU1 A;  1REW C;  1MAH F;  1ERA A;  5IMY C;  1CXN A;  1COD A;  1CDR A;  2I9B E;  6EBX A;  1CRF A;  1LXH A;  1IDH A;  1FFJ A;  1KL8 A;  3ERA A;  1VB0 A;  1KBA A;  3BT1 U;  2QC1 A;  2GOO B;  2QJB C;  2PJY C;  2QJA C;  1NEA A;  4AEA A;  1QM7 A;  2BTX A;  3NDS A;  5EBX A;  2QJ9 C;  2CCX A;  1XT3 A;  1HAA A;  1NTN A;  3U73 U;  1IDG A;  1QKE A;  1HOY A;  2FD6 U;  1V6P A;  3PLC A;  1COE A;  1IDL A;  1IDI A;  1RGJ A;  1H0J A;  1UG4 A; 
#chains in the Genus database with same CATH topology
 2MUP A;  2J8B A;  1ONJ A;  1KBT A;  1JE9 A;  1IKC A;  1KTZ B;  3VTS A;  5DO6 A;  1FSC A;  2OFS A;  2CDX A;  1LSI A;  1TFS A;  1HAJ A;  1CTX A;  1NXB A;  1JBD A;  2PJY B;  4HQP F;  2UX2 A;  1CRE A;  2JVE A;  1W6B A;  1CDT A;  2H7Z A;  4LFT A;  4OM5 A;  5DZ5 A;  3FEV A;  1CHV S;  1NTX A;  1IQ9 A;  2K3G A;  1I02 A;  1TGX A;  2H62 C;  2CRT A;  1KXI A;  2CRS A;  4FAO E;  1IK8 A;  1RL5 A;  2NBT A;  3BT2 U;  4EY8 B;  4FAO C;  3QB4 B;  1CDQ A;  4ZQY A;  4DO8 A;  2MJ4 A;  2H7Z B;  2UWR A;  1JGK A;  1LX5 B;  3HH7 A;  3LAQ U;  1IJC A;  2H5F A;  3KFD I;  2ABX A;  2ERA A;  4KSN A;  1FF4 A;  1F8U B;  1L4W A;  2HLR A;  1HC9 A;  1G6M A;  4OM4 A;  1TXB A;  3EVS C;  2MUO A;  1ES7 B;  1ABT A;  2MJY A;  1KBS A;  2X8B B;  2MHY A;  1FSS B;  2MJ0 A;  4UY2 C;  4BDT B;  3NEQ A;  2H8U A;  3KFD E;  1CXO A;  1LXG A;  3EBX A;  2H62 D;  1NYS A;  1F94 A;  1TXA A;  2H64 C;  1FRA A;  2BHI A;  1MR6 A;  2CTX A;  4IYE A;  1M9Z A;  2L03 A;  1CDS A;  1KU6 B;  1CVO A;  2LCR A;  3U74 U;  5IMT D;  1DRS A;  1CCQ A;  3NH7 A;  4P7U A;  4RUD A;  1QKD A;  1ERG A;  4QTI U;  1NOR A;  2GOO C;  2N99 A;  2JQP A;  1B41 B;  1S4Y A;  1ZAD A;  2VLW A;  1KC4 A;  1PLO A;  1CB9 A;  1HC9 B;  2L5S A;  1BTE A;  1KS6 A;  4BIK B;  1KFH A;  2MFA A;  1YWH A;  1NYU A;  1BXP A;  2HLQ A;  2H64 B;  1LJZ A;  4XJJ A;  1FAS A;  2LA1 A;  5DU1 A;  1REW C;  1MAH F;  1ERA A;  5IMY C;  1CXN A;  1COD A;  1CDR A;  2I9B E;  6EBX A;  1CRF A;  1LXH A;  1IDH A;  1FFJ A;  1KL8 A;  3ERA A;  1VB0 A;  1KBA A;  3BT1 U;  2QC1 A;  2GOO B;  2QJB C;  2PJY C;  2QJA C;  1NEA A;  4AEA A;  1QM7 A;  2BTX A;  3NDS A;  5EBX A;  2QJ9 C;  2CCX A;  1XT3 A;  1HAA A;  1NTN A;  3U73 U;  1IDG A;  1QKE A;  1HOY A;  2FD6 U;  1V6P A;  3PLC A;  1COE A;  1IDL A;  1IDI A;  1RGJ A;  1H0J A;  1UG4 A; 
#chains in the Genus database with same CATH homology
 2MUP A;  2J8B A;  1ONJ A;  1KBT A;  1JE9 A;  1IKC A;  1KTZ B;  3VTS A;  5DO6 A;  1FSC A;  2OFS A;  2CDX A;  1LSI A;  1TFS A;  1HAJ A;  1CTX A;  1NXB A;  1JBD A;  2PJY B;  4HQP F;  2UX2 A;  1CRE A;  2JVE A;  1W6B A;  1CDT A;  2H7Z A;  4LFT A;  4OM5 A;  5DZ5 A;  3FEV A;  1CHV S;  1NTX A;  1IQ9 A;  2K3G A;  1I02 A;  1TGX A;  2H62 C;  2CRT A;  1KXI A;  2CRS A;  4FAO E;  1IK8 A;  1RL5 A;  2NBT A;  3BT2 U;  4EY8 B;  4FAO C;  3QB4 B;  1CDQ A;  4ZQY A;  4DO8 A;  2MJ4 A;  2H7Z B;  2UWR A;  1JGK A;  1LX5 B;  3HH7 A;  3LAQ U;  1IJC A;  2H5F A;  3KFD I;  2ABX A;  2ERA A;  4KSN A;  1FF4 A;  1F8U B;  1L4W A;  2HLR A;  1HC9 A;  1G6M A;  4OM4 A;  1TXB A;  3EVS C;  2MUO A;  1ES7 B;  1ABT A;  2MJY A;  1KBS A;  2X8B B;  2MHY A;  1FSS B;  2MJ0 A;  4UY2 C;  4BDT B;  3NEQ A;  2H8U A;  3KFD E;  1CXO A;  1LXG A;  3EBX A;  2H62 D;  1NYS A;  1F94 A;  1TXA A;  2H64 C;  1FRA A;  2BHI A;  1MR6 A;  2CTX A;  4IYE A;  1M9Z A;  2L03 A;  1CDS A;  1KU6 B;  1CVO A;  2LCR A;  3U74 U;  5IMT D;  1DRS A;  1CCQ A;  3NH7 A;  4P7U A;  4RUD A;  1QKD A;  1ERG A;  4QTI U;  1NOR A;  2GOO C;  2N99 A;  2JQP A;  1B41 B;  1S4Y A;  1ZAD A;  2VLW A;  1KC4 A;  1PLO A;  1CB9 A;  1HC9 B;  2L5S A;  1BTE A;  1KS6 A;  4BIK B;  1KFH A;  2MFA A;  1YWH A;  1NYU A;  1BXP A;  2HLQ A;  2H64 B;  1LJZ A;  4XJJ A;  1FAS A;  2LA1 A;  5DU1 A;  1REW C;  1MAH F;  1ERA A;  5IMY C;  1CXN A;  1COD A;  1CDR A;  2I9B E;  6EBX A;  1CRF A;  1LXH A;  1IDH A;  1FFJ A;  1KL8 A;  3ERA A;  1VB0 A;  1KBA A;  3BT1 U;  2QC1 A;  2GOO B;  2QJB C;  2PJY C;  2QJA C;  1NEA A;  4AEA A;  1QM7 A;  2BTX A;  3NDS A;  5EBX A;  2QJ9 C;  2CCX A;  1XT3 A;  1HAA A;  1NTN A;  3U73 U;  1IDG A;  1QKE A;  1HOY A;  2FD6 U;  1V6P A;  3PLC A;  1COE A;  1IDL A;  1IDI A;  1RGJ A;  1H0J A;  1UG4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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