5DU1A

Crystal structure of dendroaspis polylepis mambalgin-1 wild-type in p21 space group.
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
57
structure length
57
Chain Sequence
LKCYQHGKVVTCHRDMKFCYHNTGMPFRNLKLILQGCSSSCSETENNKCCSTDRCNK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition.
pubmed doi rcsb
molecule keywords Mambalgin-1
molecule tags Toxin
total genus 12
structure length 57
sequence length 57
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2015-09-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 5du1A00
1M9ZA 2H64B 1CB9A 2NBTA 2ABXA 2MJ0A 4P7UA 1CDRA 2H5FA 3EVSC 1KXIA 1NORA 4ZQYA 1ABTA 2BHIA 2VLWA 1NXBA 3VTSA 1I02A 1NTNA 1LJZA 5EBXA 3BT1U 4BDTB 1KBAA 4UY2C 1COEA 1QKDA 2H62C 2J8BA 2CTXA 1NYSA 1HAJA 1KFHA 1L4WA 2JVEA 1IDGA 1LSIA 1UG4A 2H8UA 5IMYC 1KBTA 1CODA 2PJYC 3HH7A 1IDLA 3QB4B 1PLOA 1TXBA 1IQ9A 1B41B 1TXAA 1S4YA 1LX5B 4FAOC 1XT3A 2MUPA 2L03A 4QTIU 4HQPF 1JGKA 1KC4A 1CDTA 3U74U 1CCQA 2CRSA 2GOOC 3NH7A 3EBXA 1W6BA 1RGJA 2MJYA 2OFSA 1RL5A 2CDXA 1IKCA 6EBXA 1MAHF 2QC1A 3KFDI 1CXOA 1TGXA 1IJCA 1FSCA 2PJYB 1ERGA 2ERAA 4AEAA 2LCRA 1BTEA 2K3GA 4OM5A 5DO6A 4FAOE 1CTXA 1YWHA 1DRSA 3NDSA 1VB0A 2QJAC 3PLCA 1JBDA 3LAQU 3ERAA 2GOOB 1CDSA 1JE9A 1FFJA 1KS6A 1BXPA 1KBSA 1CRFA 3U73U 2H64C 5DU1A 1KU6B 1F94A 3KFDE 1CREA 4IYEA 1KTZB 1CHVS 1LXGA 4BIKB 2I9BE 2CRTA 2H62D 1F8UB 2H7ZA 1CDQA 5IMTD 2H7ZB 2MJ4A 1KL8A 1REWC 2BTXA 1MR6A 2UWRA 3BT2U 2CCXA 2QJ9C 1HOYA 1H0JA 1NEAA 2LA1A 1IDIA 4RUDA 1QKEA 2MUOA 2X8BB 1NTXA 2HLQA 1FF4A 4LFTA 5DZ5A 2JQPA 1LXHA 1CVOA 3FEVA 4EY8B 1FSSB 1HC9A 1HC9B 1ES7B 4DO8A 1ONJA 1HAAA 1ZADA 3NEQA 1QM7A 2QJBC 4XJJA 2N99A 1FRAA 2HLRA 1FASA 2UX2A 4OM4A 1G6MA 2MFAA 1IDHA 1V6PA 1IK8A 2L5SA 2MHYA 1CXNA 1TFSA 1ERAA 2FD6U 1NYUA
chains in the Genus database with same CATH superfamily
1M9ZA 2H64B 1CB9A 2NBTA 2ABXA 2MJ0A 4P7UA 1CDRA 2H5FA 3EVSC 1KXIA 1NORA 4ZQYA 1ABTA 2BHIA 2VLWA 1NXBA 3VTSA 1I02A 1NTNA 1LJZA 5EBXA 3BT1U 4BDTB 1KBAA 4UY2C 1COEA 1QKDA 2H62C 2J8BA 2CTXA 1NYSA 1HAJA 1KFHA 1L4WA 2JVEA 1IDGA 1LSIA 1UG4A 2H8UA 5IMYC 1KBTA 1CODA 2PJYC 3HH7A 1IDLA 3QB4B 1PLOA 1TXBA 1IQ9A 1B41B 1TXAA 1S4YA 4KSNA 1LX5B 4FAOC 1XT3A 2MUPA 2L03A 4QTIU 4HQPF 1JGKA 1KC4A 1CDTA 3U74U 1CCQA 2CRSA 2GOOC 3NH7A 3EBXA 1W6BA 1RGJA 2MJYA 2OFSA 1RL5A 2CDXA 1IKCA 6EBXA 1MAHF 2QC1A 3KFDI 1CXOA 1TGXA 1IJCA 1FSCA 2PJYB 1ERGA 2ERAA 4AEAA 2LCRA 1BTEA 2K3GA 4OM5A 5DO6A 4FAOE 1CTXA 1YWHA 1DRSA 3NDSA 1VB0A 2QJAC 3PLCA 1JBDA 3LAQU 3ERAA 2GOOB 1CDSA 1JE9A 1FFJA 1KS6A 1BXPA 1KBSA 1CRFA 3U73U 2H64C 5DU1A 1KU6B 1F94A 3KFDE 1CREA 4IYEA 1KTZB 1CHVS 1LXGA 4BIKB 2I9BE 2CRTA 2H62D 1F8UB 2H7ZA 1CDQA 5IMTD 2H7ZB 2MJ4A 1KL8A 1REWC 2BTXA 1MR6A 2UWRA 3BT2U 2CCXA 2QJ9C 1HOYA 1H0JA 1NEAA 2LA1A 1IDIA 4RUDA 1QKEA 2MUOA 2X8BB 1NTXA 2HLQA 1FF4A 4LFTA 5DZ5A 2JQPA 1LXHA 1CVOA 3FEVA 4EY8B 1FSSB 1HC9A 1HC9B 1ES7B 4DO8A 1ONJA 1HAAA 1ZADA 3NEQA 1QM7A 2QJBC 4XJJA 2N99A 1FRAA 2HLRA 1FASA 2UX2A 4OM4A 1G6MA 2MFAA 1IDHA 1V6PA 1IK8A 2L5SA 2MHYA 1CXNA 1TFSA 1ERAA 2FD6U 1NYUA
chains in the Genus database with same CATH topology
1M9ZA 2H64B 1CB9A 2NBTA 2ABXA 2MJ0A 4P7UA 1CDRA 2H5FA 3EVSC 1KXIA 1NORA 4ZQYA 1ABTA 2BHIA 2VLWA 1NXBA 3VTSA 1I02A 1NTNA 1LJZA 5EBXA 3BT1U 4BDTB 1KBAA 4UY2C 1COEA 1QKDA 2H62C 2J8BA 2CTXA 1NYSA 1HAJA 1KFHA 1L4WA 2JVEA 1IDGA 1LSIA 1UG4A 2H8UA 5IMYC 1KBTA 1CODA 2PJYC 3HH7A 1IDLA 3QB4B 1PLOA 1TXBA 1IQ9A 1B41B 1TXAA 1S4YA 4KSNA 1LX5B 4FAOC 1XT3A 2MUPA 2L03A 4QTIU 4HQPF 1JGKA 1KC4A 1CDTA 3U74U 1CCQA 2CRSA 2GOOC 3NH7A 3EBXA 1W6BA 1RGJA 2MJYA 2OFSA 1RL5A 2CDXA 1IKCA 6EBXA 1MAHF 2QC1A 3KFDI 1CXOA 1TGXA 1IJCA 1FSCA 2PJYB 1ERGA 2ERAA 4AEAA 2LCRA 1BTEA 2K3GA 4OM5A 5DO6A 4FAOE 1CTXA 1YWHA 1DRSA 3NDSA 1VB0A 2QJAC 3PLCA 1JBDA 3LAQU 3ERAA 2GOOB 1CDSA 1JE9A 1FFJA 1KS6A 1BXPA 1KBSA 1CRFA 3U73U 2H64C 5DU1A 1KU6B 1F94A 3KFDE 1CREA 4IYEA 1KTZB 1CHVS 1LXGA 4BIKB 2I9BE 2CRTA 2H62D 1F8UB 2H7ZA 1CDQA 5IMTD 2H7ZB 2MJ4A 1KL8A 1REWC 2BTXA 1MR6A 2UWRA 3BT2U 2CCXA 2QJ9C 1HOYA 1H0JA 1NEAA 2LA1A 1IDIA 4RUDA 1QKEA 2MUOA 2X8BB 1NTXA 2HLQA 1FF4A 4LFTA 5DZ5A 2JQPA 1LXHA 1CVOA 3FEVA 4EY8B 1FSSB 1HC9A 1HC9B 1ES7B 4DO8A 1ONJA 1HAAA 1ZADA 3NEQA 1QM7A 2QJBC 4XJJA 2N99A 1FRAA 2HLRA 1FASA 2UX2A 4OM4A 1G6MA 2MFAA 1IDHA 1V6PA 1IK8A 2L5SA 2MHYA 1CXNA 1TFSA 1ERAA 2FD6U 1NYUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M9Z A;  2H64 B;  1CB9 A;  2NBT A;  2ABX A;  2MJ0 A;  4P7U A;  1CDR A;  2H5F A;  3EVS C;  1KXI A;  1NOR A;  4ZQY A;  1ABT A;  2BHI A;  2VLW A;  1NXB A;  3VTS A;  1I02 A;  1NTN A;  1LJZ A;  5EBX A;  3BT1 U;  4BDT B;  1KBA A;  4UY2 C;  1COE A;  1QKD A;  2H62 C;  2J8B A;  2CTX A;  1NYS A;  1HAJ A;  1KFH A;  1L4W A;  2JVE A;  1IDG A;  1LSI A;  1UG4 A;  2H8U A;  5IMY C;  1KBT A;  1COD A;  2PJY C;  3HH7 A;  1IDL A;  3QB4 B;  1PLO A;  1TXB A;  1IQ9 A;  1B41 B;  1TXA A;  1S4Y A;  1LX5 B;  4FAO C;  1XT3 A;  2MUP A;  2L03 A;  4QTI U;  4HQP F;  1JGK A;  1KC4 A;  1CDT A;  3U74 U;  1CCQ A;  2CRS A;  2GOO C;  3NH7 A;  3EBX A;  1W6B A;  1RGJ A;  2MJY A;  2OFS A;  1RL5 A;  2CDX A;  1IKC A;  6EBX A;  1MAH F;  2QC1 A;  3KFD I;  1CXO A;  1TGX A;  1IJC A;  1FSC A;  2PJY B;  1ERG A;  2ERA A;  4AEA A;  2LCR A;  1BTE A;  2K3G A;  4OM5 A;  5DO6 A;  4FAO E;  1CTX A;  1YWH A;  1DRS A;  3NDS A;  1VB0 A;  2QJA C;  3PLC A;  1JBD A;  3LAQ U;  3ERA A;  2GOO B;  1CDS A;  1JE9 A;  1FFJ A;  1KS6 A;  1BXP A;  1KBS A;  1CRF A;  3U73 U;  2H64 C;  5DU1 A;  1KU6 B;  1F94 A;  3KFD E;  1CRE A;  4IYE A;  1KTZ B;  1CHV S;  1LXG A;  4BIK B;  2I9B E;  2CRT A;  2H62 D;  1F8U B;  2H7Z A;  1CDQ A;  5IMT D;  2H7Z B;  2MJ4 A;  1KL8 A;  1REW C;  2BTX A;  1MR6 A;  2UWR A;  3BT2 U;  2CCX A;  2QJ9 C;  1HOY A;  1H0J A;  1NEA A;  2LA1 A;  1IDI A;  4RUD A;  1QKE A;  2MUO A;  2X8B B;  1NTX A;  2HLQ A;  1FF4 A;  4LFT A;  5DZ5 A;  2JQP A;  1LXH A;  1CVO A;  3FEV A;  4EY8 B;  1FSS B;  1HC9 A;  1HC9 B;  1ES7 B;  4DO8 A;  1ONJ A;  1HAA A;  1ZAD A;  3NEQ A;  1QM7 A;  2QJB C;  4XJJ A;  2N99 A;  1FRA A;  2HLR A;  1FAS A;  2UX2 A;  4OM4 A;  1G6M A;  2MFA A;  1IDH A;  1V6P A;  1IK8 A;  2L5S A;  2MHY A;  1CXN A;  1TFS A;  1ERA A;  2FD6 U;  1NYU A; 
#chains in the Genus database with same CATH topology
 1M9Z A;  2H64 B;  1CB9 A;  2NBT A;  2ABX A;  2MJ0 A;  4P7U A;  1CDR A;  2H5F A;  3EVS C;  1KXI A;  1NOR A;  4ZQY A;  1ABT A;  2BHI A;  2VLW A;  1NXB A;  3VTS A;  1I02 A;  1NTN A;  1LJZ A;  5EBX A;  3BT1 U;  4BDT B;  1KBA A;  4UY2 C;  1COE A;  1QKD A;  2H62 C;  2J8B A;  2CTX A;  1NYS A;  1HAJ A;  1KFH A;  1L4W A;  2JVE A;  1IDG A;  1LSI A;  1UG4 A;  2H8U A;  5IMY C;  1KBT A;  1COD A;  2PJY C;  3HH7 A;  1IDL A;  3QB4 B;  1PLO A;  1TXB A;  1IQ9 A;  1B41 B;  1TXA A;  1S4Y A;  4KSN A;  1LX5 B;  4FAO C;  1XT3 A;  2MUP A;  2L03 A;  4QTI U;  4HQP F;  1JGK A;  1KC4 A;  1CDT A;  3U74 U;  1CCQ A;  2CRS A;  2GOO C;  3NH7 A;  3EBX A;  1W6B A;  1RGJ A;  2MJY A;  2OFS A;  1RL5 A;  2CDX A;  1IKC A;  6EBX A;  1MAH F;  2QC1 A;  3KFD I;  1CXO A;  1TGX A;  1IJC A;  1FSC A;  2PJY B;  1ERG A;  2ERA A;  4AEA A;  2LCR A;  1BTE A;  2K3G A;  4OM5 A;  5DO6 A;  4FAO E;  1CTX A;  1YWH A;  1DRS A;  3NDS A;  1VB0 A;  2QJA C;  3PLC A;  1JBD A;  3LAQ U;  3ERA A;  2GOO B;  1CDS A;  1JE9 A;  1FFJ A;  1KS6 A;  1BXP A;  1KBS A;  1CRF A;  3U73 U;  2H64 C;  5DU1 A;  1KU6 B;  1F94 A;  3KFD E;  1CRE A;  4IYE A;  1KTZ B;  1CHV S;  1LXG A;  4BIK B;  2I9B E;  2CRT A;  2H62 D;  1F8U B;  2H7Z A;  1CDQ A;  5IMT D;  2H7Z B;  2MJ4 A;  1KL8 A;  1REW C;  2BTX A;  1MR6 A;  2UWR A;  3BT2 U;  2CCX A;  2QJ9 C;  1HOY A;  1H0J A;  1NEA A;  2LA1 A;  1IDI A;  4RUD A;  1QKE A;  2MUO A;  2X8B B;  1NTX A;  2HLQ A;  1FF4 A;  4LFT A;  5DZ5 A;  2JQP A;  1LXH A;  1CVO A;  3FEV A;  4EY8 B;  1FSS B;  1HC9 A;  1HC9 B;  1ES7 B;  4DO8 A;  1ONJ A;  1HAA A;  1ZAD A;  3NEQ A;  1QM7 A;  2QJB C;  4XJJ A;  2N99 A;  1FRA A;  2HLR A;  1FAS A;  2UX2 A;  4OM4 A;  1G6M A;  2MFA A;  1IDH A;  1V6P A;  1IK8 A;  2L5S A;  2MHY A;  1CXN A;  1TFS A;  1ERA A;  2FD6 U;  1NYU A; 
#chains in the Genus database with same CATH homology
 1M9Z A;  2H64 B;  1CB9 A;  2NBT A;  2ABX A;  2MJ0 A;  4P7U A;  1CDR A;  2H5F A;  3EVS C;  1KXI A;  1NOR A;  4ZQY A;  1ABT A;  2BHI A;  2VLW A;  1NXB A;  3VTS A;  1I02 A;  1NTN A;  1LJZ A;  5EBX A;  3BT1 U;  4BDT B;  1KBA A;  4UY2 C;  1COE A;  1QKD A;  2H62 C;  2J8B A;  2CTX A;  1NYS A;  1HAJ A;  1KFH A;  1L4W A;  2JVE A;  1IDG A;  1LSI A;  1UG4 A;  2H8U A;  5IMY C;  1KBT A;  1COD A;  2PJY C;  3HH7 A;  1IDL A;  3QB4 B;  1PLO A;  1TXB A;  1IQ9 A;  1B41 B;  1TXA A;  1S4Y A;  4KSN A;  1LX5 B;  4FAO C;  1XT3 A;  2MUP A;  2L03 A;  4QTI U;  4HQP F;  1JGK A;  1KC4 A;  1CDT A;  3U74 U;  1CCQ A;  2CRS A;  2GOO C;  3NH7 A;  3EBX A;  1W6B A;  1RGJ A;  2MJY A;  2OFS A;  1RL5 A;  2CDX A;  1IKC A;  6EBX A;  1MAH F;  2QC1 A;  3KFD I;  1CXO A;  1TGX A;  1IJC A;  1FSC A;  2PJY B;  1ERG A;  2ERA A;  4AEA A;  2LCR A;  1BTE A;  2K3G A;  4OM5 A;  5DO6 A;  4FAO E;  1CTX A;  1YWH A;  1DRS A;  3NDS A;  1VB0 A;  2QJA C;  3PLC A;  1JBD A;  3LAQ U;  3ERA A;  2GOO B;  1CDS A;  1JE9 A;  1FFJ A;  1KS6 A;  1BXP A;  1KBS A;  1CRF A;  3U73 U;  2H64 C;  5DU1 A;  1KU6 B;  1F94 A;  3KFD E;  1CRE A;  4IYE A;  1KTZ B;  1CHV S;  1LXG A;  4BIK B;  2I9B E;  2CRT A;  2H62 D;  1F8U B;  2H7Z A;  1CDQ A;  5IMT D;  2H7Z B;  2MJ4 A;  1KL8 A;  1REW C;  2BTX A;  1MR6 A;  2UWR A;  3BT2 U;  2CCX A;  2QJ9 C;  1HOY A;  1H0J A;  1NEA A;  2LA1 A;  1IDI A;  4RUD A;  1QKE A;  2MUO A;  2X8B B;  1NTX A;  2HLQ A;  1FF4 A;  4LFT A;  5DZ5 A;  2JQP A;  1LXH A;  1CVO A;  3FEV A;  4EY8 B;  1FSS B;  1HC9 A;  1HC9 B;  1ES7 B;  4DO8 A;  1ONJ A;  1HAA A;  1ZAD A;  3NEQ A;  1QM7 A;  2QJB C;  4XJJ A;  2N99 A;  1FRA A;  2HLR A;  1FAS A;  2UX2 A;  4OM4 A;  1G6M A;  2MFA A;  1IDH A;  1V6P A;  1IK8 A;  2L5S A;  2MHY A;  1CXN A;  1TFS A;  1ERA A;  2FD6 U;  1NYU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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