2BHIA

Crystal structure of taiwan cobra cardiotoxin a3 complexed with sulfogalactoceramide
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
60
structure length
60
Chain Sequence
LKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Glycosphingolipid-Facilitated Membrane Insertion and Internalization of Cobra Cardiotoxin: The Sulfatide/Cardiotoxin Complex Structure in a Membrane-Like Environment Suggests a Lipid-Dependent Cell-Penetrating Mechanism for Membrane Binding Polypeptides.
pubmed doi rcsb
molecule tags Cardiotoxin
molecule keywords CYTOTOXIN 3
total genus 11
structure length 60
sequence length 60
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-01-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 2bhiA00
2MUPA 2HLRA 1KTZB 3HH7A 1B41B 1ERAA 1NORA 2QJAC 1QM7A 3U74U 4QTIU 1KL8A 1IKCA 1CDRA 1CCQA 2CTXA 1BXPA 4FAOE 3KFDE 1ONJA 1REWC 4AEAA 1LXGA 1CHVS 1VB0A 2LA1A 1CVOA 1ABTA 3QB4B 3BT1U 2L03A 4DO8A 1RGJA 2BTXA 2GOOC 1ERGA 4RUDA 2NBTA 4UY2C 1ZADA 2JVEA 1FSSB 2OFSA 1KBSA 1CB9A 2H62C 1W6BA 5DZ5A 2H64C 2CDXA 1KC4A 1CTXA 2K3GA 2QC1A 1FRAA 1G6MA 2I9BE 1IDHA 2H62D 1V6PA 1TXAA 1MR6A 2CRTA 1YWHA 1S4YA 1IJCA 1UG4A 1MAHF 2VLWA 4OM4A 2MJ4A 1ES7B 3ERAA 2MFAA 3BT2U 3FEVA 5DO6A 1IDGA 1CRFA 1CREA 1XT3A 1CDSA 1LJZA 1F94A 1L4WA 1FASA 1PLOA 3NEQA 1NXBA 4HQPF 2J8BA 1IK8A 4ZQYA 4P7UA 1CDTA 1IQ9A 1IDIA 4FAOC 1HOYA 1LSIA 1NTXA 2L5SA 2CRSA 3EBXA 1CXOA 2PJYC 1JBDA 1QKDA 6EBXA 1JE9A 2GOOB 1I02A 1CDQA 1DRSA 1LXHA 1TXBA 2BHIA 1FFJA 1HAJA 2H5FA 4LFTA 5DU1A 1JGKA 2MJ0A 1KBAA 2H64B 1HC9A 1NYUA 3KFDI 3NDSA 1IDLA 2QJBC 1FSCA 1QKEA 1HC9B 2MHYA 4EY8B 4BDTB 1FF4A 2X8BB 3LAQU 1KXIA 3PLCA 1CODA 1HAAA 1BTEA 2MJYA 2UWRA 4IYEA 2MUOA 1KU6B 3VTSA 4XJJA 2N99A 2UX2A 1NTNA 2CCXA 2ERAA 2JQPA 1CXNA 3U73U 1M9ZA 1TFSA 2H8UA 4BIKB 1KBTA 4OM5A 2LCRA 2H7ZA 3EVSC 1LX5B 1COEA 2FD6U 1TGXA 2ABXA 2HLQA 1NYSA 5IMYC 5IMTD 1KFHA 1H0JA 1RL5A 2H7ZB 3NH7A 5EBXA 2QJ9C 2PJYB 1F8UB 1NEAA 1KS6A
chains in the Genus database with same CATH superfamily
2MUPA 2HLRA 1KTZB 3HH7A 1B41B 1ERAA 1NORA 2QJAC 4KSNA 1QM7A 3U74U 4QTIU 1KL8A 1IKCA 1CDRA 1CCQA 2CTXA 1BXPA 4FAOE 3KFDE 1ONJA 1REWC 4AEAA 1LXGA 1CHVS 1VB0A 2LA1A 1CVOA 1ABTA 3QB4B 3BT1U 2L03A 4DO8A 1RGJA 2BTXA 2GOOC 1ERGA 4RUDA 2NBTA 4UY2C 1ZADA 2JVEA 1FSSB 2OFSA 1KBSA 1CB9A 2H62C 1W6BA 5DZ5A 2H64C 2CDXA 1KC4A 1CTXA 2K3GA 2QC1A 1FRAA 1G6MA 2I9BE 1IDHA 2H62D 1V6PA 1TXAA 1MR6A 2CRTA 1YWHA 1S4YA 1IJCA 1UG4A 1MAHF 2VLWA 4OM4A 2MJ4A 1ES7B 3ERAA 2MFAA 3BT2U 3FEVA 5DO6A 1IDGA 1CRFA 1CREA 1XT3A 1CDSA 1LJZA 1F94A 1L4WA 1FASA 1PLOA 3NEQA 1NXBA 4HQPF 2J8BA 1IK8A 4ZQYA 4P7UA 1CDTA 1IQ9A 1IDIA 4FAOC 1HOYA 1LSIA 1NTXA 2L5SA 2CRSA 3EBXA 1CXOA 2PJYC 1JBDA 1QKDA 6EBXA 1JE9A 2GOOB 1I02A 1CDQA 1DRSA 1LXHA 1TXBA 2BHIA 1FFJA 1HAJA 2H5FA 4LFTA 5DU1A 1JGKA 2MJ0A 1KBAA 2H64B 1HC9A 1NYUA 3KFDI 3NDSA 1IDLA 2QJBC 1FSCA 1QKEA 1HC9B 2MHYA 4EY8B 4BDTB 1FF4A 2X8BB 3LAQU 1KXIA 3PLCA 1CODA 1HAAA 1BTEA 2MJYA 2UWRA 4IYEA 2MUOA 1KU6B 3VTSA 4XJJA 2N99A 2UX2A 1NTNA 2CCXA 2ERAA 2JQPA 1CXNA 3U73U 1M9ZA 1TFSA 2H8UA 4BIKB 1KBTA 4OM5A 2LCRA 2H7ZA 3EVSC 1LX5B 1COEA 2FD6U 1TGXA 2ABXA 2HLQA 1NYSA 5IMYC 5IMTD 1KFHA 1H0JA 1RL5A 2H7ZB 3NH7A 5EBXA 2QJ9C 2PJYB 1F8UB 1NEAA 1KS6A
chains in the Genus database with same CATH topology
2MUPA 2HLRA 1KTZB 3HH7A 1B41B 1ERAA 1NORA 2QJAC 4KSNA 1QM7A 3U74U 4QTIU 1KL8A 1IKCA 1CDRA 1CCQA 2CTXA 1BXPA 4FAOE 3KFDE 1ONJA 1REWC 4AEAA 1LXGA 1CHVS 1VB0A 2LA1A 1CVOA 1ABTA 3QB4B 3BT1U 2L03A 4DO8A 1RGJA 2BTXA 2GOOC 1ERGA 4RUDA 2NBTA 4UY2C 1ZADA 2JVEA 1FSSB 2OFSA 1KBSA 1CB9A 2H62C 1W6BA 5DZ5A 2H64C 2CDXA 1KC4A 1CTXA 2K3GA 2QC1A 1FRAA 1G6MA 2I9BE 1IDHA 2H62D 1V6PA 1TXAA 1MR6A 2CRTA 1YWHA 1S4YA 1IJCA 1UG4A 1MAHF 2VLWA 4OM4A 2MJ4A 1ES7B 3ERAA 2MFAA 3BT2U 3FEVA 5DO6A 1IDGA 1CRFA 1CREA 1XT3A 1CDSA 1LJZA 1F94A 1L4WA 1FASA 1PLOA 3NEQA 1NXBA 4HQPF 2J8BA 1IK8A 4ZQYA 4P7UA 1CDTA 1IQ9A 1IDIA 4FAOC 1HOYA 1LSIA 1NTXA 2L5SA 2CRSA 3EBXA 1CXOA 2PJYC 1JBDA 1QKDA 6EBXA 1JE9A 2GOOB 1I02A 1CDQA 1DRSA 1LXHA 1TXBA 2BHIA 1FFJA 1HAJA 2H5FA 4LFTA 5DU1A 1JGKA 2MJ0A 1KBAA 2H64B 1HC9A 1NYUA 3KFDI 3NDSA 1IDLA 2QJBC 1FSCA 1QKEA 1HC9B 2MHYA 4EY8B 4BDTB 1FF4A 2X8BB 3LAQU 1KXIA 3PLCA 1CODA 1HAAA 1BTEA 2MJYA 2UWRA 4IYEA 2MUOA 1KU6B 3VTSA 4XJJA 2N99A 2UX2A 1NTNA 2CCXA 2ERAA 2JQPA 1CXNA 3U73U 1M9ZA 1TFSA 2H8UA 4BIKB 1KBTA 4OM5A 2LCRA 2H7ZA 3EVSC 1LX5B 1COEA 2FD6U 1TGXA 2ABXA 2HLQA 1NYSA 5IMYC 5IMTD 1KFHA 1H0JA 1RL5A 2H7ZB 3NH7A 5EBXA 2QJ9C 2PJYB 1F8UB 1NEAA 1KS6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MUP A;  2HLR A;  1KTZ B;  3HH7 A;  1B41 B;  1ERA A;  1NOR A;  2QJA C;  1QM7 A;  3U74 U;  4QTI U;  1KL8 A;  1IKC A;  1CDR A;  1CCQ A;  2CTX A;  1BXP A;  4FAO E;  3KFD E;  1ONJ A;  1REW C;  4AEA A;  1LXG A;  1CHV S;  1VB0 A;  2LA1 A;  1CVO A;  1ABT A;  3QB4 B;  3BT1 U;  2L03 A;  4DO8 A;  1RGJ A;  2BTX A;  2GOO C;  1ERG A;  4RUD A;  2NBT A;  4UY2 C;  1ZAD A;  2JVE A;  1FSS B;  2OFS A;  1KBS A;  1CB9 A;  2H62 C;  1W6B A;  5DZ5 A;  2H64 C;  2CDX A;  1KC4 A;  1CTX A;  2K3G A;  2QC1 A;  1FRA A;  1G6M A;  2I9B E;  1IDH A;  2H62 D;  1V6P A;  1TXA A;  1MR6 A;  2CRT A;  1YWH A;  1S4Y A;  1IJC A;  1UG4 A;  1MAH F;  2VLW A;  4OM4 A;  2MJ4 A;  1ES7 B;  3ERA A;  2MFA A;  3BT2 U;  3FEV A;  5DO6 A;  1IDG A;  1CRF A;  1CRE A;  1XT3 A;  1CDS A;  1LJZ A;  1F94 A;  1L4W A;  1FAS A;  1PLO A;  3NEQ A;  1NXB A;  4HQP F;  2J8B A;  1IK8 A;  4ZQY A;  4P7U A;  1CDT A;  1IQ9 A;  1IDI A;  4FAO C;  1HOY A;  1LSI A;  1NTX A;  2L5S A;  2CRS A;  3EBX A;  1CXO A;  2PJY C;  1JBD A;  1QKD A;  6EBX A;  1JE9 A;  2GOO B;  1I02 A;  1CDQ A;  1DRS A;  1LXH A;  1TXB A;  2BHI A;  1FFJ A;  1HAJ A;  2H5F A;  4LFT A;  5DU1 A;  1JGK A;  2MJ0 A;  1KBA A;  2H64 B;  1HC9 A;  1NYU A;  3KFD I;  3NDS A;  1IDL A;  2QJB C;  1FSC A;  1QKE A;  1HC9 B;  2MHY A;  4EY8 B;  4BDT B;  1FF4 A;  2X8B B;  3LAQ U;  1KXI A;  3PLC A;  1COD A;  1HAA A;  1BTE A;  2MJY A;  2UWR A;  4IYE A;  2MUO A;  1KU6 B;  3VTS A;  4XJJ A;  2N99 A;  2UX2 A;  1NTN A;  2CCX A;  2ERA A;  2JQP A;  1CXN A;  3U73 U;  1M9Z A;  1TFS A;  2H8U A;  4BIK B;  1KBT A;  4OM5 A;  2LCR A;  2H7Z A;  3EVS C;  1LX5 B;  1COE A;  2FD6 U;  1TGX A;  2ABX A;  2HLQ A;  1NYS A;  5IMY C;  5IMT D;  1KFH A;  1H0J A;  1RL5 A;  2H7Z B;  3NH7 A;  5EBX A;  2QJ9 C;  2PJY B;  1F8U B;  1NEA A;  1KS6 A; 
#chains in the Genus database with same CATH topology
 2MUP A;  2HLR A;  1KTZ B;  3HH7 A;  1B41 B;  1ERA A;  1NOR A;  2QJA C;  4KSN A;  1QM7 A;  3U74 U;  4QTI U;  1KL8 A;  1IKC A;  1CDR A;  1CCQ A;  2CTX A;  1BXP A;  4FAO E;  3KFD E;  1ONJ A;  1REW C;  4AEA A;  1LXG A;  1CHV S;  1VB0 A;  2LA1 A;  1CVO A;  1ABT A;  3QB4 B;  3BT1 U;  2L03 A;  4DO8 A;  1RGJ A;  2BTX A;  2GOO C;  1ERG A;  4RUD A;  2NBT A;  4UY2 C;  1ZAD A;  2JVE A;  1FSS B;  2OFS A;  1KBS A;  1CB9 A;  2H62 C;  1W6B A;  5DZ5 A;  2H64 C;  2CDX A;  1KC4 A;  1CTX A;  2K3G A;  2QC1 A;  1FRA A;  1G6M A;  2I9B E;  1IDH A;  2H62 D;  1V6P A;  1TXA A;  1MR6 A;  2CRT A;  1YWH A;  1S4Y A;  1IJC A;  1UG4 A;  1MAH F;  2VLW A;  4OM4 A;  2MJ4 A;  1ES7 B;  3ERA A;  2MFA A;  3BT2 U;  3FEV A;  5DO6 A;  1IDG A;  1CRF A;  1CRE A;  1XT3 A;  1CDS A;  1LJZ A;  1F94 A;  1L4W A;  1FAS A;  1PLO A;  3NEQ A;  1NXB A;  4HQP F;  2J8B A;  1IK8 A;  4ZQY A;  4P7U A;  1CDT A;  1IQ9 A;  1IDI A;  4FAO C;  1HOY A;  1LSI A;  1NTX A;  2L5S A;  2CRS A;  3EBX A;  1CXO A;  2PJY C;  1JBD A;  1QKD A;  6EBX A;  1JE9 A;  2GOO B;  1I02 A;  1CDQ A;  1DRS A;  1LXH A;  1TXB A;  2BHI A;  1FFJ A;  1HAJ A;  2H5F A;  4LFT A;  5DU1 A;  1JGK A;  2MJ0 A;  1KBA A;  2H64 B;  1HC9 A;  1NYU A;  3KFD I;  3NDS A;  1IDL A;  2QJB C;  1FSC A;  1QKE A;  1HC9 B;  2MHY A;  4EY8 B;  4BDT B;  1FF4 A;  2X8B B;  3LAQ U;  1KXI A;  3PLC A;  1COD A;  1HAA A;  1BTE A;  2MJY A;  2UWR A;  4IYE A;  2MUO A;  1KU6 B;  3VTS A;  4XJJ A;  2N99 A;  2UX2 A;  1NTN A;  2CCX A;  2ERA A;  2JQP A;  1CXN A;  3U73 U;  1M9Z A;  1TFS A;  2H8U A;  4BIK B;  1KBT A;  4OM5 A;  2LCR A;  2H7Z A;  3EVS C;  1LX5 B;  1COE A;  2FD6 U;  1TGX A;  2ABX A;  2HLQ A;  1NYS A;  5IMY C;  5IMT D;  1KFH A;  1H0J A;  1RL5 A;  2H7Z B;  3NH7 A;  5EBX A;  2QJ9 C;  2PJY B;  1F8U B;  1NEA A;  1KS6 A; 
#chains in the Genus database with same CATH homology
 2MUP A;  2HLR A;  1KTZ B;  3HH7 A;  1B41 B;  1ERA A;  1NOR A;  2QJA C;  4KSN A;  1QM7 A;  3U74 U;  4QTI U;  1KL8 A;  1IKC A;  1CDR A;  1CCQ A;  2CTX A;  1BXP A;  4FAO E;  3KFD E;  1ONJ A;  1REW C;  4AEA A;  1LXG A;  1CHV S;  1VB0 A;  2LA1 A;  1CVO A;  1ABT A;  3QB4 B;  3BT1 U;  2L03 A;  4DO8 A;  1RGJ A;  2BTX A;  2GOO C;  1ERG A;  4RUD A;  2NBT A;  4UY2 C;  1ZAD A;  2JVE A;  1FSS B;  2OFS A;  1KBS A;  1CB9 A;  2H62 C;  1W6B A;  5DZ5 A;  2H64 C;  2CDX A;  1KC4 A;  1CTX A;  2K3G A;  2QC1 A;  1FRA A;  1G6M A;  2I9B E;  1IDH A;  2H62 D;  1V6P A;  1TXA A;  1MR6 A;  2CRT A;  1YWH A;  1S4Y A;  1IJC A;  1UG4 A;  1MAH F;  2VLW A;  4OM4 A;  2MJ4 A;  1ES7 B;  3ERA A;  2MFA A;  3BT2 U;  3FEV A;  5DO6 A;  1IDG A;  1CRF A;  1CRE A;  1XT3 A;  1CDS A;  1LJZ A;  1F94 A;  1L4W A;  1FAS A;  1PLO A;  3NEQ A;  1NXB A;  4HQP F;  2J8B A;  1IK8 A;  4ZQY A;  4P7U A;  1CDT A;  1IQ9 A;  1IDI A;  4FAO C;  1HOY A;  1LSI A;  1NTX A;  2L5S A;  2CRS A;  3EBX A;  1CXO A;  2PJY C;  1JBD A;  1QKD A;  6EBX A;  1JE9 A;  2GOO B;  1I02 A;  1CDQ A;  1DRS A;  1LXH A;  1TXB A;  2BHI A;  1FFJ A;  1HAJ A;  2H5F A;  4LFT A;  5DU1 A;  1JGK A;  2MJ0 A;  1KBA A;  2H64 B;  1HC9 A;  1NYU A;  3KFD I;  3NDS A;  1IDL A;  2QJB C;  1FSC A;  1QKE A;  1HC9 B;  2MHY A;  4EY8 B;  4BDT B;  1FF4 A;  2X8B B;  3LAQ U;  1KXI A;  3PLC A;  1COD A;  1HAA A;  1BTE A;  2MJY A;  2UWR A;  4IYE A;  2MUO A;  1KU6 B;  3VTS A;  4XJJ A;  2N99 A;  2UX2 A;  1NTN A;  2CCX A;  2ERA A;  2JQP A;  1CXN A;  3U73 U;  1M9Z A;  1TFS A;  2H8U A;  4BIK B;  1KBT A;  4OM5 A;  2LCR A;  2H7Z A;  3EVS C;  1LX5 B;  1COE A;  2FD6 U;  1TGX A;  2ABX A;  2HLQ A;  1NYS A;  5IMY C;  5IMT D;  1KFH A;  1H0J A;  1RL5 A;  2H7Z B;  3NH7 A;  5EBX A;  2QJ9 C;  2PJY B;  1F8U B;  1NEA A;  1KS6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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