2K3GA

Nmr structure analysis of a bmp receptor
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
102
structure length
102
Chain Sequence
GPEDTLPFLKCYCSGHCPDDAINNTCITNGHCFAIIEEDDQGETTLASGCMKYEGSDFQCKDSPKAQLRRTIECCRTNLCNQYLQPTLPPVVIGPFFDGSIR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The solution structure of BMPR-IA reveals a local disorder-to-order transition upon BMP-2 binding.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Bone morphogenetic protein receptor type-1A
total genus 6
structure length 102
sequence length 102
ec nomenclature ec 2.7.11.30: Receptor protein serine/threonine kinase.
pdb deposition date 2008-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01064 Activin_recp Activin types I and II receptor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 2k3gA00
1LX5B 1PLOA 1JBDA 4OM5A 2JVEA 2H64C 2CTXA 1TXBA 2LCRA 1ONJA 3NDSA 2H7ZA 2QJAC 2UWRA 1NORA 1IDHA 1KBTA 1CCQA 1ES7B 1CTXA 3EVSC 1TXAA 4QTIU 1FFJA 1CDQA 1H0JA 2CRSA 1NYUA 1CODA 2FD6U 1LSIA 2PJYC 1IJCA 1IQ9A 4ZQYA 1FASA 1COEA 1HOYA 1KTZB 2BTXA 2QC1A 2JQPA 1NXBA 2CCXA 2QJ9C 1CXOA 1XT3A 2X8BB 2MUPA 2NBTA 1MAHF 1KS6A 1YWHA 1QM7A 1TGXA 1HC9B 2H62D 2H5FA 1HAJA 1NTNA 1LXGA 3LAQU 1FRAA 2MJ4A 2GOOC 1FSCA 2OFSA 4RUDA 3KFDE 1RL5A 4DO8A 2L03A 1CXNA 2BHIA 2H64B 2H8UA 1LXHA 3NH7A 3ERAA 1HAAA 1IDIA 2MUOA 1KFHA 2L5SA 5IMTD 1CDRA 1NEAA 4OM4A 1NTXA 4FAOE 2HLRA 1CRFA 4UY2C 4BIKB 1KU6B 2H7ZB 2MFAA 3NEQA 4HQPF 3EBXA 1CVOA 1JE9A 1KL8A 4IYEA 2PJYB 1CDTA 1CHVS 3U74U 1JGKA 2ERAA 3QB4B 1BTEA 1ERGA 2H62C 2MJ0A 3HH7A 1IDLA 4BDTB 1FSSB 2VLWA 1CB9A 1IDGA 1I02A 1UG4A 1LJZA 2QJBC 1DRSA 5DU1A 1QKDA 1QKEA 4FAOC 1CDSA 1V6PA 1F94A 1TFSA 5DZ5A 2GOOB 1IK8A 2CDXA 1KXIA 1REWC 1W6BA 1CREA 3PLCA 6EBXA 1MR6A 2UX2A 1B41B 1M9ZA 1KBSA 4XJJA 2ABXA 1KC4A 1S4YA 3BT1U 1L4WA 1KBAA 1ZADA 2I9BE 4AEAA 1F8UB 4LFTA 3KFDI 1G6MA 5IMYC 1BXPA 5EBXA 1IKCA 1HC9A 1FF4A 3FEVA 4EY8B 2MJYA 1ERAA 3U73U 2LA1A 2N99A 4P7UA 1RGJA 2HLQA 2MHYA 2CRTA 1VB0A 3VTSA 1ABTA 5DO6A 1NYSA 3BT2U 2K3GA 2J8BA
chains in the Genus database with same CATH superfamily
1LX5B 1PLOA 1JBDA 4OM5A 2JVEA 2H64C 2CTXA 1TXBA 2LCRA 1ONJA 3NDSA 2H7ZA 2QJAC 2UWRA 1NORA 1IDHA 1KBTA 1CCQA 1ES7B 1CTXA 3EVSC 1TXAA 4QTIU 1FFJA 1CDQA 1H0JA 2CRSA 1NYUA 1CODA 2FD6U 1LSIA 2PJYC 1IJCA 1IQ9A 4ZQYA 1FASA 1COEA 1HOYA 1KTZB 2BTXA 2QC1A 2JQPA 1NXBA 2CCXA 2QJ9C 1CXOA 1XT3A 2X8BB 2MUPA 2NBTA 1MAHF 1KS6A 1YWHA 1QM7A 4KSNA 1TGXA 1HC9B 2H62D 2H5FA 1HAJA 1NTNA 1LXGA 3LAQU 1FRAA 2MJ4A 2GOOC 1FSCA 2OFSA 4RUDA 3KFDE 1RL5A 4DO8A 2L03A 1CXNA 2BHIA 2H64B 2H8UA 1LXHA 3NH7A 3ERAA 1HAAA 1IDIA 2MUOA 1KFHA 2L5SA 5IMTD 1CDRA 1NEAA 4OM4A 1NTXA 4FAOE 2HLRA 1CRFA 4UY2C 4BIKB 1KU6B 2H7ZB 2MFAA 3NEQA 4HQPF 3EBXA 1CVOA 1JE9A 1KL8A 4IYEA 2PJYB 1CDTA 1CHVS 3U74U 1JGKA 2ERAA 3QB4B 1BTEA 1ERGA 2H62C 2MJ0A 3HH7A 1IDLA 4BDTB 1FSSB 2VLWA 1CB9A 1IDGA 1I02A 1UG4A 1LJZA 2QJBC 1DRSA 5DU1A 1QKDA 1QKEA 4FAOC 1CDSA 1V6PA 1F94A 1TFSA 5DZ5A 2GOOB 1IK8A 2CDXA 1KXIA 1REWC 1W6BA 1CREA 3PLCA 6EBXA 1MR6A 2UX2A 1B41B 1M9ZA 1KBSA 4XJJA 2ABXA 1KC4A 1S4YA 3BT1U 1L4WA 1KBAA 1ZADA 2I9BE 4AEAA 1F8UB 4LFTA 3KFDI 1G6MA 5IMYC 1BXPA 5EBXA 1IKCA 1HC9A 1FF4A 3FEVA 4EY8B 2MJYA 1ERAA 3U73U 2LA1A 2N99A 4P7UA 1RGJA 2HLQA 2MHYA 2CRTA 1VB0A 3VTSA 1ABTA 5DO6A 1NYSA 3BT2U 2K3GA 2J8BA
chains in the Genus database with same CATH topology
1LX5B 1PLOA 1JBDA 4OM5A 2JVEA 2H64C 2CTXA 1TXBA 2LCRA 1ONJA 3NDSA 2H7ZA 2QJAC 2UWRA 1NORA 1IDHA 1KBTA 1CCQA 1ES7B 1CTXA 3EVSC 1TXAA 4QTIU 1FFJA 1CDQA 1H0JA 2CRSA 1NYUA 1CODA 2FD6U 1LSIA 2PJYC 1IJCA 1IQ9A 4ZQYA 1FASA 1COEA 1HOYA 1KTZB 2BTXA 2QC1A 2JQPA 1NXBA 2CCXA 2QJ9C 1CXOA 1XT3A 2X8BB 2MUPA 2NBTA 1MAHF 1KS6A 1YWHA 1QM7A 4KSNA 1TGXA 1HC9B 2H62D 2H5FA 1HAJA 1NTNA 1LXGA 3LAQU 1FRAA 2MJ4A 2GOOC 1FSCA 2OFSA 4RUDA 3KFDE 1RL5A 4DO8A 2L03A 1CXNA 2BHIA 2H64B 2H8UA 1LXHA 3NH7A 3ERAA 1HAAA 1IDIA 2MUOA 1KFHA 2L5SA 5IMTD 1CDRA 1NEAA 4OM4A 1NTXA 4FAOE 2HLRA 1CRFA 4UY2C 4BIKB 1KU6B 2H7ZB 2MFAA 3NEQA 4HQPF 3EBXA 1CVOA 1JE9A 1KL8A 4IYEA 2PJYB 1CDTA 1CHVS 3U74U 1JGKA 2ERAA 3QB4B 1BTEA 1ERGA 2H62C 2MJ0A 3HH7A 1IDLA 4BDTB 1FSSB 2VLWA 1CB9A 1IDGA 1I02A 1UG4A 1LJZA 2QJBC 1DRSA 5DU1A 1QKDA 1QKEA 4FAOC 1CDSA 1V6PA 1F94A 1TFSA 5DZ5A 2GOOB 1IK8A 2CDXA 1KXIA 1REWC 1W6BA 1CREA 3PLCA 6EBXA 1MR6A 2UX2A 1B41B 1M9ZA 1KBSA 4XJJA 2ABXA 1KC4A 1S4YA 3BT1U 1L4WA 1KBAA 1ZADA 2I9BE 4AEAA 1F8UB 4LFTA 3KFDI 1G6MA 5IMYC 1BXPA 5EBXA 1IKCA 1HC9A 1FF4A 3FEVA 4EY8B 2MJYA 1ERAA 3U73U 2LA1A 2N99A 4P7UA 1RGJA 2HLQA 2MHYA 2CRTA 1VB0A 3VTSA 1ABTA 5DO6A 1NYSA 3BT2U 2K3GA 2J8BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LX5 B;  1PLO A;  1JBD A;  4OM5 A;  2JVE A;  2H64 C;  2CTX A;  1TXB A;  2LCR A;  1ONJ A;  3NDS A;  2H7Z A;  2QJA C;  2UWR A;  1NOR A;  1IDH A;  1KBT A;  1CCQ A;  1ES7 B;  1CTX A;  3EVS C;  1TXA A;  4QTI U;  1FFJ A;  1CDQ A;  1H0J A;  2CRS A;  1NYU A;  1COD A;  2FD6 U;  1LSI A;  2PJY C;  1IJC A;  1IQ9 A;  4ZQY A;  1FAS A;  1COE A;  1HOY A;  1KTZ B;  2BTX A;  2QC1 A;  2JQP A;  1NXB A;  2CCX A;  2QJ9 C;  1CXO A;  1XT3 A;  2X8B B;  2MUP A;  2NBT A;  1MAH F;  1KS6 A;  1YWH A;  1QM7 A;  1TGX A;  1HC9 B;  2H62 D;  2H5F A;  1HAJ A;  1NTN A;  1LXG A;  3LAQ U;  1FRA A;  2MJ4 A;  2GOO C;  1FSC A;  2OFS A;  4RUD A;  3KFD E;  1RL5 A;  4DO8 A;  2L03 A;  1CXN A;  2BHI A;  2H64 B;  2H8U A;  1LXH A;  3NH7 A;  3ERA A;  1HAA A;  1IDI A;  2MUO A;  1KFH A;  2L5S A;  5IMT D;  1CDR A;  1NEA A;  4OM4 A;  1NTX A;  4FAO E;  2HLR A;  1CRF A;  4UY2 C;  4BIK B;  1KU6 B;  2H7Z B;  2MFA A;  3NEQ A;  4HQP F;  3EBX A;  1CVO A;  1JE9 A;  1KL8 A;  4IYE A;  2PJY B;  1CDT A;  1CHV S;  3U74 U;  1JGK A;  2ERA A;  3QB4 B;  1BTE A;  1ERG A;  2H62 C;  2MJ0 A;  3HH7 A;  1IDL A;  4BDT B;  1FSS B;  2VLW A;  1CB9 A;  1IDG A;  1I02 A;  1UG4 A;  1LJZ A;  2QJB C;  1DRS A;  5DU1 A;  1QKD A;  1QKE A;  4FAO C;  1CDS A;  1V6P A;  1F94 A;  1TFS A;  5DZ5 A;  2GOO B;  1IK8 A;  2CDX A;  1KXI A;  1REW C;  1W6B A;  1CRE A;  3PLC A;  6EBX A;  1MR6 A;  2UX2 A;  1B41 B;  1M9Z A;  1KBS A;  4XJJ A;  2ABX A;  1KC4 A;  1S4Y A;  3BT1 U;  1L4W A;  1KBA A;  1ZAD A;  2I9B E;  4AEA A;  1F8U B;  4LFT A;  3KFD I;  1G6M A;  5IMY C;  1BXP A;  5EBX A;  1IKC A;  1HC9 A;  1FF4 A;  3FEV A;  4EY8 B;  2MJY A;  1ERA A;  3U73 U;  2LA1 A;  2N99 A;  4P7U A;  1RGJ A;  2HLQ A;  2MHY A;  2CRT A;  1VB0 A;  3VTS A;  1ABT A;  5DO6 A;  1NYS A;  3BT2 U;  2K3G A;  2J8B A; 
#chains in the Genus database with same CATH topology
 1LX5 B;  1PLO A;  1JBD A;  4OM5 A;  2JVE A;  2H64 C;  2CTX A;  1TXB A;  2LCR A;  1ONJ A;  3NDS A;  2H7Z A;  2QJA C;  2UWR A;  1NOR A;  1IDH A;  1KBT A;  1CCQ A;  1ES7 B;  1CTX A;  3EVS C;  1TXA A;  4QTI U;  1FFJ A;  1CDQ A;  1H0J A;  2CRS A;  1NYU A;  1COD A;  2FD6 U;  1LSI A;  2PJY C;  1IJC A;  1IQ9 A;  4ZQY A;  1FAS A;  1COE A;  1HOY A;  1KTZ B;  2BTX A;  2QC1 A;  2JQP A;  1NXB A;  2CCX A;  2QJ9 C;  1CXO A;  1XT3 A;  2X8B B;  2MUP A;  2NBT A;  1MAH F;  1KS6 A;  1YWH A;  1QM7 A;  4KSN A;  1TGX A;  1HC9 B;  2H62 D;  2H5F A;  1HAJ A;  1NTN A;  1LXG A;  3LAQ U;  1FRA A;  2MJ4 A;  2GOO C;  1FSC A;  2OFS A;  4RUD A;  3KFD E;  1RL5 A;  4DO8 A;  2L03 A;  1CXN A;  2BHI A;  2H64 B;  2H8U A;  1LXH A;  3NH7 A;  3ERA A;  1HAA A;  1IDI A;  2MUO A;  1KFH A;  2L5S A;  5IMT D;  1CDR A;  1NEA A;  4OM4 A;  1NTX A;  4FAO E;  2HLR A;  1CRF A;  4UY2 C;  4BIK B;  1KU6 B;  2H7Z B;  2MFA A;  3NEQ A;  4HQP F;  3EBX A;  1CVO A;  1JE9 A;  1KL8 A;  4IYE A;  2PJY B;  1CDT A;  1CHV S;  3U74 U;  1JGK A;  2ERA A;  3QB4 B;  1BTE A;  1ERG A;  2H62 C;  2MJ0 A;  3HH7 A;  1IDL A;  4BDT B;  1FSS B;  2VLW A;  1CB9 A;  1IDG A;  1I02 A;  1UG4 A;  1LJZ A;  2QJB C;  1DRS A;  5DU1 A;  1QKD A;  1QKE A;  4FAO C;  1CDS A;  1V6P A;  1F94 A;  1TFS A;  5DZ5 A;  2GOO B;  1IK8 A;  2CDX A;  1KXI A;  1REW C;  1W6B A;  1CRE A;  3PLC A;  6EBX A;  1MR6 A;  2UX2 A;  1B41 B;  1M9Z A;  1KBS A;  4XJJ A;  2ABX A;  1KC4 A;  1S4Y A;  3BT1 U;  1L4W A;  1KBA A;  1ZAD A;  2I9B E;  4AEA A;  1F8U B;  4LFT A;  3KFD I;  1G6M A;  5IMY C;  1BXP A;  5EBX A;  1IKC A;  1HC9 A;  1FF4 A;  3FEV A;  4EY8 B;  2MJY A;  1ERA A;  3U73 U;  2LA1 A;  2N99 A;  4P7U A;  1RGJ A;  2HLQ A;  2MHY A;  2CRT A;  1VB0 A;  3VTS A;  1ABT A;  5DO6 A;  1NYS A;  3BT2 U;  2K3G A;  2J8B A; 
#chains in the Genus database with same CATH homology
 1LX5 B;  1PLO A;  1JBD A;  4OM5 A;  2JVE A;  2H64 C;  2CTX A;  1TXB A;  2LCR A;  1ONJ A;  3NDS A;  2H7Z A;  2QJA C;  2UWR A;  1NOR A;  1IDH A;  1KBT A;  1CCQ A;  1ES7 B;  1CTX A;  3EVS C;  1TXA A;  4QTI U;  1FFJ A;  1CDQ A;  1H0J A;  2CRS A;  1NYU A;  1COD A;  2FD6 U;  1LSI A;  2PJY C;  1IJC A;  1IQ9 A;  4ZQY A;  1FAS A;  1COE A;  1HOY A;  1KTZ B;  2BTX A;  2QC1 A;  2JQP A;  1NXB A;  2CCX A;  2QJ9 C;  1CXO A;  1XT3 A;  2X8B B;  2MUP A;  2NBT A;  1MAH F;  1KS6 A;  1YWH A;  1QM7 A;  4KSN A;  1TGX A;  1HC9 B;  2H62 D;  2H5F A;  1HAJ A;  1NTN A;  1LXG A;  3LAQ U;  1FRA A;  2MJ4 A;  2GOO C;  1FSC A;  2OFS A;  4RUD A;  3KFD E;  1RL5 A;  4DO8 A;  2L03 A;  1CXN A;  2BHI A;  2H64 B;  2H8U A;  1LXH A;  3NH7 A;  3ERA A;  1HAA A;  1IDI A;  2MUO A;  1KFH A;  2L5S A;  5IMT D;  1CDR A;  1NEA A;  4OM4 A;  1NTX A;  4FAO E;  2HLR A;  1CRF A;  4UY2 C;  4BIK B;  1KU6 B;  2H7Z B;  2MFA A;  3NEQ A;  4HQP F;  3EBX A;  1CVO A;  1JE9 A;  1KL8 A;  4IYE A;  2PJY B;  1CDT A;  1CHV S;  3U74 U;  1JGK A;  2ERA A;  3QB4 B;  1BTE A;  1ERG A;  2H62 C;  2MJ0 A;  3HH7 A;  1IDL A;  4BDT B;  1FSS B;  2VLW A;  1CB9 A;  1IDG A;  1I02 A;  1UG4 A;  1LJZ A;  2QJB C;  1DRS A;  5DU1 A;  1QKD A;  1QKE A;  4FAO C;  1CDS A;  1V6P A;  1F94 A;  1TFS A;  5DZ5 A;  2GOO B;  1IK8 A;  2CDX A;  1KXI A;  1REW C;  1W6B A;  1CRE A;  3PLC A;  6EBX A;  1MR6 A;  2UX2 A;  1B41 B;  1M9Z A;  1KBS A;  4XJJ A;  2ABX A;  1KC4 A;  1S4Y A;  3BT1 U;  1L4W A;  1KBA A;  1ZAD A;  2I9B E;  4AEA A;  1F8U B;  4LFT A;  3KFD I;  1G6M A;  5IMY C;  1BXP A;  5EBX A;  1IKC A;  1HC9 A;  1FF4 A;  3FEV A;  4EY8 B;  2MJY A;  1ERA A;  3U73 U;  2LA1 A;  2N99 A;  4P7U A;  1RGJ A;  2HLQ A;  2MHY A;  2CRT A;  1VB0 A;  3VTS A;  1ABT A;  5DO6 A;  1NYS A;  3BT2 U;  2K3G A;  2J8B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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