1REWC

Structural refinement of the complex of bone morphogenetic protein 2 and its type ia receptor
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
86
structure length
86
Chain Sequence
TLPFLKCYCSGHCPDDAINNTCITNGHCFAIIEEDDQGETTLASGCMKYEGSDFQCKDSPKAQLRRTIECCRTNLCNQYLQPTLPP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular recognition of BMP-2 and BMP receptor IA.
pubmed doi rcsb
molecule tags Hormone/growth factor/signaling protein
source organism Homo sapiens
molecule keywords bone morphogenetic protein 2
total genus 15
structure length 86
sequence length 86
chains with identical sequence D
ec nomenclature ec 2.7.11.30: Receptor protein serine/threonine kinase.
pdb deposition date 2003-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01064 Activin_recp Activin types I and II receptor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 1rewC00
1FSSB 1HC9A 1NEAA 1IDHA 1IQ9A 3KFDI 1LJZA 2ABXA 2GOOB 4DO8A 1KC4A 1V6PA 2X8BB 1F8UB 2K3GA 2H7ZA 3PLCA 2H64B 2JQPA 1IJCA 4EY8B 1B41B 2MFAA 1TGXA 2BTXA 1KBTA 1TFSA 2J8BA 2H62C 4OM5A 4P7UA 4IYEA 1CB9A 1KTZB 5DO6A 2CRTA 1PLOA 3ERAA 1NYUA 1TXAA 2ERAA 1ZADA 1CODA 2JVEA 1NTNA 1ONJA 1VB0A 4QTIU 1CREA 1H0JA 2NBTA 1BTEA 1FF4A 2GOOC 4XJJA 1KXIA 2CTXA 2LA1A 2MUOA 1IDLA 1UG4A 1HC9B 2L03A 2FD6U 2H64C 3NDSA 1JE9A 4AEAA 4BDTB 5IMYC 1ES7B 2CDXA 1BXPA 2QJ9C 2H7ZB 1ABTA 4UY2C 1COEA 1KBSA 1CDSA 1KL8A 2PJYC 1CVOA 1DRSA 3QB4B 2LCRA 1REWC 1IKCA 2QJBC 2PJYB 1CRFA 3HH7A 6EBXA 1XT3A 2MJ4A 1CDRA 1ERGA 4FAOE 3EBXA 2QC1A 1ERAA 1F94A 5EBXA 1S4YA 2H62D 1YWHA 1FSCA 1CTXA 1NXBA 1CXOA 1MAHF 3U73U 3U74U 2HLQA 3FEVA 1FASA 1KBAA 1QKEA 5IMTD 2QJAC 4OM4A 1IK8A 1QM7A 4BIKB 1CCQA 1HAJA 1JGKA 2I9BE 5DU1A 1I02A 2H5FA 1KFHA 1HOYA 2UWRA 2CRSA 2MUPA 3EVSC 2BHIA 3LAQU 1CHVS 2N99A 4HQPF 2OFSA 1RL5A 4ZQYA 1JBDA 1RGJA 3KFDE 3NEQA 1LXGA 1CXNA 1CDQA 2L5SA 5DZ5A 1M9ZA 2MJ0A 1IDGA 2UX2A 1L4WA 2MJYA 3BT1U 1KS6A 4FAOC 1G6MA 1TXBA 2VLWA 1IDIA 1LXHA 3BT2U 1W6BA 1FFJA 1KU6B 4RUDA 1LX5B 4LFTA 1LSIA 2CCXA 1NTXA 1MR6A 2H8UA 2MHYA 1FRAA 1NORA 3NH7A 1QKDA 2HLRA 1CDTA 1HAAA 1NYSA 3VTSA
chains in the Genus database with same CATH superfamily
1FSSB 1HC9A 1NEAA 1IDHA 1IQ9A 3KFDI 1LJZA 2ABXA 2GOOB 4DO8A 1KC4A 1V6PA 2X8BB 1F8UB 2K3GA 2H7ZA 3PLCA 2H64B 2JQPA 1IJCA 4EY8B 1B41B 2MFAA 1TGXA 2BTXA 1KBTA 1TFSA 2J8BA 2H62C 4OM5A 4P7UA 4IYEA 1CB9A 1KTZB 5DO6A 2CRTA 1PLOA 3ERAA 1NYUA 1TXAA 2ERAA 1ZADA 1CODA 2JVEA 1NTNA 1ONJA 1VB0A 4QTIU 1CREA 1H0JA 2NBTA 1BTEA 1FF4A 2GOOC 4XJJA 1KXIA 2CTXA 2LA1A 2MUOA 1IDLA 4KSNA 1UG4A 1HC9B 2L03A 2FD6U 2H64C 3NDSA 1JE9A 4AEAA 4BDTB 5IMYC 1ES7B 2CDXA 1BXPA 2QJ9C 2H7ZB 1ABTA 4UY2C 1COEA 1KBSA 1CDSA 1KL8A 2PJYC 1CVOA 1DRSA 3QB4B 2LCRA 1REWC 1IKCA 2QJBC 2PJYB 1CRFA 3HH7A 6EBXA 1XT3A 2MJ4A 1CDRA 1ERGA 4FAOE 3EBXA 2QC1A 1ERAA 1F94A 5EBXA 1S4YA 2H62D 1YWHA 1FSCA 1CTXA 1NXBA 1CXOA 1MAHF 3U73U 3U74U 2HLQA 3FEVA 1FASA 1KBAA 1QKEA 5IMTD 2QJAC 4OM4A 1IK8A 1QM7A 4BIKB 1CCQA 1HAJA 1JGKA 2I9BE 5DU1A 1I02A 2H5FA 1KFHA 1HOYA 2UWRA 2CRSA 2MUPA 3EVSC 2BHIA 3LAQU 1CHVS 2N99A 4HQPF 2OFSA 1RL5A 4ZQYA 1JBDA 1RGJA 3KFDE 3NEQA 1LXGA 1CXNA 1CDQA 2L5SA 5DZ5A 1M9ZA 2MJ0A 1IDGA 2UX2A 1L4WA 2MJYA 3BT1U 1KS6A 4FAOC 1G6MA 1TXBA 2VLWA 1IDIA 1LXHA 3BT2U 1W6BA 1FFJA 1KU6B 4RUDA 1LX5B 4LFTA 1LSIA 2CCXA 1NTXA 1MR6A 2H8UA 2MHYA 1FRAA 1NORA 3NH7A 1QKDA 2HLRA 1CDTA 1HAAA 1NYSA 3VTSA
chains in the Genus database with same CATH topology
1FSSB 1HC9A 1NEAA 1IDHA 1IQ9A 3KFDI 1LJZA 2ABXA 2GOOB 4DO8A 1KC4A 1V6PA 2X8BB 1F8UB 2K3GA 2H7ZA 3PLCA 2H64B 2JQPA 1IJCA 4EY8B 1B41B 2MFAA 1TGXA 2BTXA 1KBTA 1TFSA 2J8BA 2H62C 4OM5A 4P7UA 4IYEA 1CB9A 1KTZB 5DO6A 2CRTA 1PLOA 3ERAA 1NYUA 1TXAA 2ERAA 1ZADA 1CODA 2JVEA 1NTNA 1ONJA 1VB0A 4QTIU 1CREA 1H0JA 2NBTA 1BTEA 1FF4A 2GOOC 4XJJA 1KXIA 2CTXA 2LA1A 2MUOA 1IDLA 4KSNA 1UG4A 1HC9B 2L03A 2FD6U 2H64C 3NDSA 1JE9A 4AEAA 4BDTB 5IMYC 1ES7B 2CDXA 1BXPA 2QJ9C 2H7ZB 1ABTA 4UY2C 1COEA 1KBSA 1CDSA 1KL8A 2PJYC 1CVOA 1DRSA 3QB4B 2LCRA 1REWC 1IKCA 2QJBC 2PJYB 1CRFA 3HH7A 6EBXA 1XT3A 2MJ4A 1CDRA 1ERGA 4FAOE 3EBXA 2QC1A 1ERAA 1F94A 5EBXA 1S4YA 2H62D 1YWHA 1FSCA 1CTXA 1NXBA 1CXOA 1MAHF 3U73U 3U74U 2HLQA 3FEVA 1FASA 1KBAA 1QKEA 5IMTD 2QJAC 4OM4A 1IK8A 1QM7A 4BIKB 1CCQA 1HAJA 1JGKA 2I9BE 5DU1A 1I02A 2H5FA 1KFHA 1HOYA 2UWRA 2CRSA 2MUPA 3EVSC 2BHIA 3LAQU 1CHVS 2N99A 4HQPF 2OFSA 1RL5A 4ZQYA 1JBDA 1RGJA 3KFDE 3NEQA 1LXGA 1CXNA 1CDQA 2L5SA 5DZ5A 1M9ZA 2MJ0A 1IDGA 2UX2A 1L4WA 2MJYA 3BT1U 1KS6A 4FAOC 1G6MA 1TXBA 2VLWA 1IDIA 1LXHA 3BT2U 1W6BA 1FFJA 1KU6B 4RUDA 1LX5B 4LFTA 1LSIA 2CCXA 1NTXA 1MR6A 2H8UA 2MHYA 1FRAA 1NORA 3NH7A 1QKDA 2HLRA 1CDTA 1HAAA 1NYSA 3VTSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FSS B;  1HC9 A;  1NEA A;  1IDH A;  1IQ9 A;  3KFD I;  1LJZ A;  2ABX A;  2GOO B;  4DO8 A;  1KC4 A;  1V6P A;  2X8B B;  1F8U B;  2K3G A;  2H7Z A;  3PLC A;  2H64 B;  2JQP A;  1IJC A;  4EY8 B;  1B41 B;  2MFA A;  1TGX A;  2BTX A;  1KBT A;  1TFS A;  2J8B A;  2H62 C;  4OM5 A;  4P7U A;  4IYE A;  1CB9 A;  1KTZ B;  5DO6 A;  2CRT A;  1PLO A;  3ERA A;  1NYU A;  1TXA A;  2ERA A;  1ZAD A;  1COD A;  2JVE A;  1NTN A;  1ONJ A;  1VB0 A;  4QTI U;  1CRE A;  1H0J A;  2NBT A;  1BTE A;  1FF4 A;  2GOO C;  4XJJ A;  1KXI A;  2CTX A;  2LA1 A;  2MUO A;  1IDL A;  1UG4 A;  1HC9 B;  2L03 A;  2FD6 U;  2H64 C;  3NDS A;  1JE9 A;  4AEA A;  4BDT B;  5IMY C;  1ES7 B;  2CDX A;  1BXP A;  2QJ9 C;  2H7Z B;  1ABT A;  4UY2 C;  1COE A;  1KBS A;  1CDS A;  1KL8 A;  2PJY C;  1CVO A;  1DRS A;  3QB4 B;  2LCR A;  1REW C;  1IKC A;  2QJB C;  2PJY B;  1CRF A;  3HH7 A;  6EBX A;  1XT3 A;  2MJ4 A;  1CDR A;  1ERG A;  4FAO E;  3EBX A;  2QC1 A;  1ERA A;  1F94 A;  5EBX A;  1S4Y A;  2H62 D;  1YWH A;  1FSC A;  1CTX A;  1NXB A;  1CXO A;  1MAH F;  3U73 U;  3U74 U;  2HLQ A;  3FEV A;  1FAS A;  1KBA A;  1QKE A;  5IMT D;  2QJA C;  4OM4 A;  1IK8 A;  1QM7 A;  4BIK B;  1CCQ A;  1HAJ A;  1JGK A;  2I9B E;  5DU1 A;  1I02 A;  2H5F A;  1KFH A;  1HOY A;  2UWR A;  2CRS A;  2MUP A;  3EVS C;  2BHI A;  3LAQ U;  1CHV S;  2N99 A;  4HQP F;  2OFS A;  1RL5 A;  4ZQY A;  1JBD A;  1RGJ A;  3KFD E;  3NEQ A;  1LXG A;  1CXN A;  1CDQ A;  2L5S A;  5DZ5 A;  1M9Z A;  2MJ0 A;  1IDG A;  2UX2 A;  1L4W A;  2MJY A;  3BT1 U;  1KS6 A;  4FAO C;  1G6M A;  1TXB A;  2VLW A;  1IDI A;  1LXH A;  3BT2 U;  1W6B A;  1FFJ A;  1KU6 B;  4RUD A;  1LX5 B;  4LFT A;  1LSI A;  2CCX A;  1NTX A;  1MR6 A;  2H8U A;  2MHY A;  1FRA A;  1NOR A;  3NH7 A;  1QKD A;  2HLR A;  1CDT A;  1HAA A;  1NYS A;  3VTS A; 
#chains in the Genus database with same CATH topology
 1FSS B;  1HC9 A;  1NEA A;  1IDH A;  1IQ9 A;  3KFD I;  1LJZ A;  2ABX A;  2GOO B;  4DO8 A;  1KC4 A;  1V6P A;  2X8B B;  1F8U B;  2K3G A;  2H7Z A;  3PLC A;  2H64 B;  2JQP A;  1IJC A;  4EY8 B;  1B41 B;  2MFA A;  1TGX A;  2BTX A;  1KBT A;  1TFS A;  2J8B A;  2H62 C;  4OM5 A;  4P7U A;  4IYE A;  1CB9 A;  1KTZ B;  5DO6 A;  2CRT A;  1PLO A;  3ERA A;  1NYU A;  1TXA A;  2ERA A;  1ZAD A;  1COD A;  2JVE A;  1NTN A;  1ONJ A;  1VB0 A;  4QTI U;  1CRE A;  1H0J A;  2NBT A;  1BTE A;  1FF4 A;  2GOO C;  4XJJ A;  1KXI A;  2CTX A;  2LA1 A;  2MUO A;  1IDL A;  4KSN A;  1UG4 A;  1HC9 B;  2L03 A;  2FD6 U;  2H64 C;  3NDS A;  1JE9 A;  4AEA A;  4BDT B;  5IMY C;  1ES7 B;  2CDX A;  1BXP A;  2QJ9 C;  2H7Z B;  1ABT A;  4UY2 C;  1COE A;  1KBS A;  1CDS A;  1KL8 A;  2PJY C;  1CVO A;  1DRS A;  3QB4 B;  2LCR A;  1REW C;  1IKC A;  2QJB C;  2PJY B;  1CRF A;  3HH7 A;  6EBX A;  1XT3 A;  2MJ4 A;  1CDR A;  1ERG A;  4FAO E;  3EBX A;  2QC1 A;  1ERA A;  1F94 A;  5EBX A;  1S4Y A;  2H62 D;  1YWH A;  1FSC A;  1CTX A;  1NXB A;  1CXO A;  1MAH F;  3U73 U;  3U74 U;  2HLQ A;  3FEV A;  1FAS A;  1KBA A;  1QKE A;  5IMT D;  2QJA C;  4OM4 A;  1IK8 A;  1QM7 A;  4BIK B;  1CCQ A;  1HAJ A;  1JGK A;  2I9B E;  5DU1 A;  1I02 A;  2H5F A;  1KFH A;  1HOY A;  2UWR A;  2CRS A;  2MUP A;  3EVS C;  2BHI A;  3LAQ U;  1CHV S;  2N99 A;  4HQP F;  2OFS A;  1RL5 A;  4ZQY A;  1JBD A;  1RGJ A;  3KFD E;  3NEQ A;  1LXG A;  1CXN A;  1CDQ A;  2L5S A;  5DZ5 A;  1M9Z A;  2MJ0 A;  1IDG A;  2UX2 A;  1L4W A;  2MJY A;  3BT1 U;  1KS6 A;  4FAO C;  1G6M A;  1TXB A;  2VLW A;  1IDI A;  1LXH A;  3BT2 U;  1W6B A;  1FFJ A;  1KU6 B;  4RUD A;  1LX5 B;  4LFT A;  1LSI A;  2CCX A;  1NTX A;  1MR6 A;  2H8U A;  2MHY A;  1FRA A;  1NOR A;  3NH7 A;  1QKD A;  2HLR A;  1CDT A;  1HAA A;  1NYS A;  3VTS A; 
#chains in the Genus database with same CATH homology
 1FSS B;  1HC9 A;  1NEA A;  1IDH A;  1IQ9 A;  3KFD I;  1LJZ A;  2ABX A;  2GOO B;  4DO8 A;  1KC4 A;  1V6P A;  2X8B B;  1F8U B;  2K3G A;  2H7Z A;  3PLC A;  2H64 B;  2JQP A;  1IJC A;  4EY8 B;  1B41 B;  2MFA A;  1TGX A;  2BTX A;  1KBT A;  1TFS A;  2J8B A;  2H62 C;  4OM5 A;  4P7U A;  4IYE A;  1CB9 A;  1KTZ B;  5DO6 A;  2CRT A;  1PLO A;  3ERA A;  1NYU A;  1TXA A;  2ERA A;  1ZAD A;  1COD A;  2JVE A;  1NTN A;  1ONJ A;  1VB0 A;  4QTI U;  1CRE A;  1H0J A;  2NBT A;  1BTE A;  1FF4 A;  2GOO C;  4XJJ A;  1KXI A;  2CTX A;  2LA1 A;  2MUO A;  1IDL A;  4KSN A;  1UG4 A;  1HC9 B;  2L03 A;  2FD6 U;  2H64 C;  3NDS A;  1JE9 A;  4AEA A;  4BDT B;  5IMY C;  1ES7 B;  2CDX A;  1BXP A;  2QJ9 C;  2H7Z B;  1ABT A;  4UY2 C;  1COE A;  1KBS A;  1CDS A;  1KL8 A;  2PJY C;  1CVO A;  1DRS A;  3QB4 B;  2LCR A;  1REW C;  1IKC A;  2QJB C;  2PJY B;  1CRF A;  3HH7 A;  6EBX A;  1XT3 A;  2MJ4 A;  1CDR A;  1ERG A;  4FAO E;  3EBX A;  2QC1 A;  1ERA A;  1F94 A;  5EBX A;  1S4Y A;  2H62 D;  1YWH A;  1FSC A;  1CTX A;  1NXB A;  1CXO A;  1MAH F;  3U73 U;  3U74 U;  2HLQ A;  3FEV A;  1FAS A;  1KBA A;  1QKE A;  5IMT D;  2QJA C;  4OM4 A;  1IK8 A;  1QM7 A;  4BIK B;  1CCQ A;  1HAJ A;  1JGK A;  2I9B E;  5DU1 A;  1I02 A;  2H5F A;  1KFH A;  1HOY A;  2UWR A;  2CRS A;  2MUP A;  3EVS C;  2BHI A;  3LAQ U;  1CHV S;  2N99 A;  4HQP F;  2OFS A;  1RL5 A;  4ZQY A;  1JBD A;  1RGJ A;  3KFD E;  3NEQ A;  1LXG A;  1CXN A;  1CDQ A;  2L5S A;  5DZ5 A;  1M9Z A;  2MJ0 A;  1IDG A;  2UX2 A;  1L4W A;  2MJY A;  3BT1 U;  1KS6 A;  4FAO C;  1G6M A;  1TXB A;  2VLW A;  1IDI A;  1LXH A;  3BT2 U;  1W6B A;  1FFJ A;  1KU6 B;  4RUD A;  1LX5 B;  4LFT A;  1LSI A;  2CCX A;  1NTX A;  1MR6 A;  2H8U A;  2MHY A;  1FRA A;  1NOR A;  3NH7 A;  1QKD A;  2HLR A;  1CDT A;  1HAA A;  1NYS A;  3VTS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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