2QJ9C

Crystal structure analysis of bmp-2 in complex with bmpr-ia variant b1
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
86
structure length
86
Chain Sequence
TLPFLKCYCSGHCPDDAINNTCITNGHCFAIIEEDDQGETTLASGCMKYEGSDFQCRDTPIPHQRRSIECCRTNLCNQYLQPTLPP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome.
pubmed doi rcsb
molecule tags Cytokine/receptor
source organism Homo sapiens
molecule keywords Bone morphogenetic protein 2
total genus 15
structure length 86
sequence length 86
chains with identical sequence D
ec nomenclature ec 2.7.11.30: Receptor protein serine/threonine kinase.
pdb deposition date 2007-07-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01064 Activin_recp Activin types I and II receptor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 2qj9C00
5IMTD 3KFDI 5EBXA 4ZQYA 1NORA 3QB4B 2FD6U 2QJ9C 2QJBC 1FFJA 2H62D 1CVOA 1CCQA 1M9ZA 2MJYA 3HH7A 1QKEA 1TXAA 5DU1A 4BIKB 4LFTA 3KFDE 4QTIU 1ERGA 1F8UB 1H0JA 1KXIA 2NBTA 1TXBA 3NEQA 1LSIA 1KS6A 2J8BA 1LX5B 2OFSA 1FF4A 2CDXA 3BT2U 1CXOA 1KL8A 4IYEA 5DZ5A 1IDLA 1RGJA 1HAAA 1IK8A 1CODA 2MUPA 3U73U 1ERAA 1NYUA 1BTEA 1FRAA 1ABTA 2L5SA 1IDIA 2QJAC 1CDSA 1TGXA 3VTSA 3LAQU 2H7ZA 1QM7A 1UG4A 1L4WA 1CB9A 1RL5A 2MUOA 1TFSA 3BT1U 2MFAA 1NXBA 5IMYC 2JQPA 2UX2A 1HOYA 4HQPF 1CXNA 3NDSA 4OM5A 2CTXA 2LCRA 1ONJA 1KU6B 1CDQA 1JBDA 4OM4A 1I02A 1NEAA 2GOOB 2BTXA 1CTXA 4FAOC 1FSSB 1KBAA 1CDTA 1NTXA 1V6PA 2HLQA 2X8BB 1CREA 2MHYA 3U74U 2H64B 2JVEA 6EBXA 1NTNA 1CHVS 2GOOC 2H5FA 4BDTB 1JE9A 1S4YA 1ES7B 2H62C 1F94A 3PLCA 2LA1A 4FAOE 2H8UA 1XT3A 1CDRA 1HC9B 2H64C 1IDGA 1VB0A 1MR6A 2I9BE 2PJYB 1ZADA 1FSCA 2ERAA 4EY8B 1KBSA 1LXHA 1PLOA 1MAHF 1IDHA 1REWC 1B41B 2L03A 2QC1A 3FEVA 2BHIA 1KC4A 1KFHA 1KTZB 1W6BA 4AEAA 2PJYC 1BXPA 1DRSA 1FASA 2UWRA 1IKCA 2CCXA 1CRFA 1YWHA 2CRSA 4XJJA 1HC9A 2VLWA 1HAJA 1NYSA 2K3GA 1IJCA 2CRTA 1G6MA 3EVSC 3EBXA 4RUDA 2MJ4A 1IQ9A 3NH7A 2N99A 1KBTA 3ERAA 1LJZA 1JGKA 2H7ZB 2MJ0A 2ABXA 1LXGA 4DO8A 4P7UA 4UY2C 2HLRA 5DO6A 1QKDA 1COEA
chains in the Genus database with same CATH superfamily
5IMTD 3KFDI 5EBXA 4ZQYA 1NORA 3QB4B 2FD6U 2QJ9C 2QJBC 1FFJA 2H62D 1CVOA 1CCQA 1M9ZA 2MJYA 3HH7A 1QKEA 1TXAA 5DU1A 4BIKB 4LFTA 3KFDE 4QTIU 1ERGA 1F8UB 1H0JA 1KXIA 2NBTA 1TXBA 3NEQA 1LSIA 4KSNA 1KS6A 2J8BA 1LX5B 2OFSA 1FF4A 2CDXA 3BT2U 1CXOA 1KL8A 4IYEA 5DZ5A 1IDLA 1RGJA 1HAAA 1IK8A 1CODA 2MUPA 3U73U 1ERAA 1NYUA 1BTEA 1FRAA 1ABTA 2L5SA 1IDIA 2QJAC 1CDSA 1TGXA 3VTSA 3LAQU 2H7ZA 1QM7A 1UG4A 1L4WA 1CB9A 1RL5A 2MUOA 1TFSA 3BT1U 2MFAA 1NXBA 5IMYC 2JQPA 2UX2A 1HOYA 4HQPF 1CXNA 3NDSA 4OM5A 2CTXA 2LCRA 1ONJA 1KU6B 1CDQA 1JBDA 4OM4A 1I02A 1NEAA 2GOOB 2BTXA 1CTXA 4FAOC 1FSSB 1KBAA 1CDTA 1NTXA 1V6PA 2HLQA 2X8BB 1CREA 2MHYA 3U74U 2H64B 2JVEA 6EBXA 1NTNA 1CHVS 2GOOC 2H5FA 4BDTB 1JE9A 1S4YA 1ES7B 2H62C 1F94A 3PLCA 2LA1A 4FAOE 2H8UA 1XT3A 1CDRA 1HC9B 2H64C 1IDGA 1VB0A 1MR6A 2I9BE 2PJYB 1ZADA 1FSCA 2ERAA 4EY8B 1KBSA 1LXHA 1PLOA 1MAHF 1IDHA 1REWC 1B41B 2L03A 2QC1A 3FEVA 2BHIA 1KC4A 1KFHA 1KTZB 1W6BA 4AEAA 2PJYC 1BXPA 1DRSA 1FASA 2UWRA 1IKCA 2CCXA 1CRFA 1YWHA 2CRSA 4XJJA 1HC9A 2VLWA 1HAJA 1NYSA 2K3GA 1IJCA 2CRTA 1G6MA 3EVSC 3EBXA 4RUDA 2MJ4A 1IQ9A 3NH7A 2N99A 1KBTA 3ERAA 1LJZA 1JGKA 2H7ZB 2MJ0A 2ABXA 1LXGA 4DO8A 4P7UA 4UY2C 2HLRA 5DO6A 1QKDA 1COEA
chains in the Genus database with same CATH topology
5IMTD 3KFDI 5EBXA 4ZQYA 1NORA 3QB4B 2FD6U 2QJ9C 2QJBC 1FFJA 2H62D 1CVOA 1CCQA 1M9ZA 2MJYA 3HH7A 1QKEA 1TXAA 5DU1A 4BIKB 4LFTA 3KFDE 4QTIU 1ERGA 1F8UB 1H0JA 1KXIA 2NBTA 1TXBA 3NEQA 1LSIA 4KSNA 1KS6A 2J8BA 1LX5B 2OFSA 1FF4A 2CDXA 3BT2U 1CXOA 1KL8A 4IYEA 5DZ5A 1IDLA 1RGJA 1HAAA 1IK8A 1CODA 2MUPA 3U73U 1ERAA 1NYUA 1BTEA 1FRAA 1ABTA 2L5SA 1IDIA 2QJAC 1CDSA 1TGXA 3VTSA 3LAQU 2H7ZA 1QM7A 1UG4A 1L4WA 1CB9A 1RL5A 2MUOA 1TFSA 3BT1U 2MFAA 1NXBA 5IMYC 2JQPA 2UX2A 1HOYA 4HQPF 1CXNA 3NDSA 4OM5A 2CTXA 2LCRA 1ONJA 1KU6B 1CDQA 1JBDA 4OM4A 1I02A 1NEAA 2GOOB 2BTXA 1CTXA 4FAOC 1FSSB 1KBAA 1CDTA 1NTXA 1V6PA 2HLQA 2X8BB 1CREA 2MHYA 3U74U 2H64B 2JVEA 6EBXA 1NTNA 1CHVS 2GOOC 2H5FA 4BDTB 1JE9A 1S4YA 1ES7B 2H62C 1F94A 3PLCA 2LA1A 4FAOE 2H8UA 1XT3A 1CDRA 1HC9B 2H64C 1IDGA 1VB0A 1MR6A 2I9BE 2PJYB 1ZADA 1FSCA 2ERAA 4EY8B 1KBSA 1LXHA 1PLOA 1MAHF 1IDHA 1REWC 1B41B 2L03A 2QC1A 3FEVA 2BHIA 1KC4A 1KFHA 1KTZB 1W6BA 4AEAA 2PJYC 1BXPA 1DRSA 1FASA 2UWRA 1IKCA 2CCXA 1CRFA 1YWHA 2CRSA 4XJJA 1HC9A 2VLWA 1HAJA 1NYSA 2K3GA 1IJCA 2CRTA 1G6MA 3EVSC 3EBXA 4RUDA 2MJ4A 1IQ9A 3NH7A 2N99A 1KBTA 3ERAA 1LJZA 1JGKA 2H7ZB 2MJ0A 2ABXA 1LXGA 4DO8A 4P7UA 4UY2C 2HLRA 5DO6A 1QKDA 1COEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IMT D;  3KFD I;  5EBX A;  4ZQY A;  1NOR A;  3QB4 B;  2FD6 U;  2QJ9 C;  2QJB C;  1FFJ A;  2H62 D;  1CVO A;  1CCQ A;  1M9Z A;  2MJY A;  3HH7 A;  1QKE A;  1TXA A;  5DU1 A;  4BIK B;  4LFT A;  3KFD E;  4QTI U;  1ERG A;  1F8U B;  1H0J A;  1KXI A;  2NBT A;  1TXB A;  3NEQ A;  1LSI A;  1KS6 A;  2J8B A;  1LX5 B;  2OFS A;  1FF4 A;  2CDX A;  3BT2 U;  1CXO A;  1KL8 A;  4IYE A;  5DZ5 A;  1IDL A;  1RGJ A;  1HAA A;  1IK8 A;  1COD A;  2MUP A;  3U73 U;  1ERA A;  1NYU A;  1BTE A;  1FRA A;  1ABT A;  2L5S A;  1IDI A;  2QJA C;  1CDS A;  1TGX A;  3VTS A;  3LAQ U;  2H7Z A;  1QM7 A;  1UG4 A;  1L4W A;  1CB9 A;  1RL5 A;  2MUO A;  1TFS A;  3BT1 U;  2MFA A;  1NXB A;  5IMY C;  2JQP A;  2UX2 A;  1HOY A;  4HQP F;  1CXN A;  3NDS A;  4OM5 A;  2CTX A;  2LCR A;  1ONJ A;  1KU6 B;  1CDQ A;  1JBD A;  4OM4 A;  1I02 A;  1NEA A;  2GOO B;  2BTX A;  1CTX A;  4FAO C;  1FSS B;  1KBA A;  1CDT A;  1NTX A;  1V6P A;  2HLQ A;  2X8B B;  1CRE A;  2MHY A;  3U74 U;  2H64 B;  2JVE A;  6EBX A;  1NTN A;  1CHV S;  2GOO C;  2H5F A;  4BDT B;  1JE9 A;  1S4Y A;  1ES7 B;  2H62 C;  1F94 A;  3PLC A;  2LA1 A;  4FAO E;  2H8U A;  1XT3 A;  1CDR A;  1HC9 B;  2H64 C;  1IDG A;  1VB0 A;  1MR6 A;  2I9B E;  2PJY B;  1ZAD A;  1FSC A;  2ERA A;  4EY8 B;  1KBS A;  1LXH A;  1PLO A;  1MAH F;  1IDH A;  1REW C;  1B41 B;  2L03 A;  2QC1 A;  3FEV A;  2BHI A;  1KC4 A;  1KFH A;  1KTZ B;  1W6B A;  4AEA A;  2PJY C;  1BXP A;  1DRS A;  1FAS A;  2UWR A;  1IKC A;  2CCX A;  1CRF A;  1YWH A;  2CRS A;  4XJJ A;  1HC9 A;  2VLW A;  1HAJ A;  1NYS A;  2K3G A;  1IJC A;  2CRT A;  1G6M A;  3EVS C;  3EBX A;  4RUD A;  2MJ4 A;  1IQ9 A;  3NH7 A;  2N99 A;  1KBT A;  3ERA A;  1LJZ A;  1JGK A;  2H7Z B;  2MJ0 A;  2ABX A;  1LXG A;  4DO8 A;  4P7U A;  4UY2 C;  2HLR A;  5DO6 A;  1QKD A;  1COE A; 
#chains in the Genus database with same CATH topology
 5IMT D;  3KFD I;  5EBX A;  4ZQY A;  1NOR A;  3QB4 B;  2FD6 U;  2QJ9 C;  2QJB C;  1FFJ A;  2H62 D;  1CVO A;  1CCQ A;  1M9Z A;  2MJY A;  3HH7 A;  1QKE A;  1TXA A;  5DU1 A;  4BIK B;  4LFT A;  3KFD E;  4QTI U;  1ERG A;  1F8U B;  1H0J A;  1KXI A;  2NBT A;  1TXB A;  3NEQ A;  1LSI A;  4KSN A;  1KS6 A;  2J8B A;  1LX5 B;  2OFS A;  1FF4 A;  2CDX A;  3BT2 U;  1CXO A;  1KL8 A;  4IYE A;  5DZ5 A;  1IDL A;  1RGJ A;  1HAA A;  1IK8 A;  1COD A;  2MUP A;  3U73 U;  1ERA A;  1NYU A;  1BTE A;  1FRA A;  1ABT A;  2L5S A;  1IDI A;  2QJA C;  1CDS A;  1TGX A;  3VTS A;  3LAQ U;  2H7Z A;  1QM7 A;  1UG4 A;  1L4W A;  1CB9 A;  1RL5 A;  2MUO A;  1TFS A;  3BT1 U;  2MFA A;  1NXB A;  5IMY C;  2JQP A;  2UX2 A;  1HOY A;  4HQP F;  1CXN A;  3NDS A;  4OM5 A;  2CTX A;  2LCR A;  1ONJ A;  1KU6 B;  1CDQ A;  1JBD A;  4OM4 A;  1I02 A;  1NEA A;  2GOO B;  2BTX A;  1CTX A;  4FAO C;  1FSS B;  1KBA A;  1CDT A;  1NTX A;  1V6P A;  2HLQ A;  2X8B B;  1CRE A;  2MHY A;  3U74 U;  2H64 B;  2JVE A;  6EBX A;  1NTN A;  1CHV S;  2GOO C;  2H5F A;  4BDT B;  1JE9 A;  1S4Y A;  1ES7 B;  2H62 C;  1F94 A;  3PLC A;  2LA1 A;  4FAO E;  2H8U A;  1XT3 A;  1CDR A;  1HC9 B;  2H64 C;  1IDG A;  1VB0 A;  1MR6 A;  2I9B E;  2PJY B;  1ZAD A;  1FSC A;  2ERA A;  4EY8 B;  1KBS A;  1LXH A;  1PLO A;  1MAH F;  1IDH A;  1REW C;  1B41 B;  2L03 A;  2QC1 A;  3FEV A;  2BHI A;  1KC4 A;  1KFH A;  1KTZ B;  1W6B A;  4AEA A;  2PJY C;  1BXP A;  1DRS A;  1FAS A;  2UWR A;  1IKC A;  2CCX A;  1CRF A;  1YWH A;  2CRS A;  4XJJ A;  1HC9 A;  2VLW A;  1HAJ A;  1NYS A;  2K3G A;  1IJC A;  2CRT A;  1G6M A;  3EVS C;  3EBX A;  4RUD A;  2MJ4 A;  1IQ9 A;  3NH7 A;  2N99 A;  1KBT A;  3ERA A;  1LJZ A;  1JGK A;  2H7Z B;  2MJ0 A;  2ABX A;  1LXG A;  4DO8 A;  4P7U A;  4UY2 C;  2HLR A;  5DO6 A;  1QKD A;  1COE A; 
#chains in the Genus database with same CATH homology
 5IMT D;  3KFD I;  5EBX A;  4ZQY A;  1NOR A;  3QB4 B;  2FD6 U;  2QJ9 C;  2QJB C;  1FFJ A;  2H62 D;  1CVO A;  1CCQ A;  1M9Z A;  2MJY A;  3HH7 A;  1QKE A;  1TXA A;  5DU1 A;  4BIK B;  4LFT A;  3KFD E;  4QTI U;  1ERG A;  1F8U B;  1H0J A;  1KXI A;  2NBT A;  1TXB A;  3NEQ A;  1LSI A;  4KSN A;  1KS6 A;  2J8B A;  1LX5 B;  2OFS A;  1FF4 A;  2CDX A;  3BT2 U;  1CXO A;  1KL8 A;  4IYE A;  5DZ5 A;  1IDL A;  1RGJ A;  1HAA A;  1IK8 A;  1COD A;  2MUP A;  3U73 U;  1ERA A;  1NYU A;  1BTE A;  1FRA A;  1ABT A;  2L5S A;  1IDI A;  2QJA C;  1CDS A;  1TGX A;  3VTS A;  3LAQ U;  2H7Z A;  1QM7 A;  1UG4 A;  1L4W A;  1CB9 A;  1RL5 A;  2MUO A;  1TFS A;  3BT1 U;  2MFA A;  1NXB A;  5IMY C;  2JQP A;  2UX2 A;  1HOY A;  4HQP F;  1CXN A;  3NDS A;  4OM5 A;  2CTX A;  2LCR A;  1ONJ A;  1KU6 B;  1CDQ A;  1JBD A;  4OM4 A;  1I02 A;  1NEA A;  2GOO B;  2BTX A;  1CTX A;  4FAO C;  1FSS B;  1KBA A;  1CDT A;  1NTX A;  1V6P A;  2HLQ A;  2X8B B;  1CRE A;  2MHY A;  3U74 U;  2H64 B;  2JVE A;  6EBX A;  1NTN A;  1CHV S;  2GOO C;  2H5F A;  4BDT B;  1JE9 A;  1S4Y A;  1ES7 B;  2H62 C;  1F94 A;  3PLC A;  2LA1 A;  4FAO E;  2H8U A;  1XT3 A;  1CDR A;  1HC9 B;  2H64 C;  1IDG A;  1VB0 A;  1MR6 A;  2I9B E;  2PJY B;  1ZAD A;  1FSC A;  2ERA A;  4EY8 B;  1KBS A;  1LXH A;  1PLO A;  1MAH F;  1IDH A;  1REW C;  1B41 B;  2L03 A;  2QC1 A;  3FEV A;  2BHI A;  1KC4 A;  1KFH A;  1KTZ B;  1W6B A;  4AEA A;  2PJY C;  1BXP A;  1DRS A;  1FAS A;  2UWR A;  1IKC A;  2CCX A;  1CRF A;  1YWH A;  2CRS A;  4XJJ A;  1HC9 A;  2VLW A;  1HAJ A;  1NYS A;  2K3G A;  1IJC A;  2CRT A;  1G6M A;  3EVS C;  3EBX A;  4RUD A;  2MJ4 A;  1IQ9 A;  3NH7 A;  2N99 A;  1KBT A;  3ERA A;  1LJZ A;  1JGK A;  2H7Z B;  2MJ0 A;  2ABX A;  1LXG A;  4DO8 A;  4P7U A;  4UY2 C;  2HLR A;  5DO6 A;  1QKD A;  1COE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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