1FSCA

Crystal structure of fasciculin 2 from green mamba snake venom: evidence for unusual loop flexibility
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
61
structure length
61
Chain Sequence
TMCYSHTTTSRAILTNCGENSCYRKSRRHPPKMVLGRGCGCPPGDDNLEVKCCTSPDKCNY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of fasciculin 2 from green mamba snake venom: evidence for unusual loop flexibility.
pubmed doi rcsb
source organism Dendroaspis angusticeps
molecule tags Snake toxin
molecule keywords FASCICULIN 2
total genus 13
structure length 61
sequence length 61
ec nomenclature
pdb deposition date 1995-03-27
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 1fscA00
5IMTD 3ERAA 2QC1A 1V6PA 2BTXA 1TXAA 1NEAA 2CRSA 1M9ZA 1RL5A 1CDRA 1IDGA 2LA1A 2L5SA 1VB0A 1YWHA 5IMYC 3NDSA 2H62D 2H64B 1KXIA 1ERAA 1QM7A 1ABTA 1NORA 1NTXA 1CODA 1I02A 1IDLA 2CCXA 1KBSA 2MHYA 1LXGA 1IJCA 1FRAA 3HH7A 3KFDI 2H8UA 1TXBA 1MR6A 2X8BB 4EY8B 4IYEA 2JVEA 2OFSA 6EBXA 1ES7B 3FEVA 1FF4A 4XJJA 2GOOC 2H7ZA 1FASA 4BIKB 1KFHA 2CRTA 1HAJA 4BDTB 1TGXA 2CTXA 4UY2C 3VTSA 1DRSA 1JE9A 1JBDA 3LAQU 1H0JA 2H7ZB 1TFSA 1B41B 1IDIA 2K3GA 1JGKA 2ABXA 1COEA 3BT2U 2CDXA 1IK8A 1CXNA 1CXOA 2LCRA 1L4WA 2QJ9C 3U73U 1QKDA 2BHIA 3BT1U 1CDQA 1KU6B 4P7UA 4ZQYA 1FFJA 2JQPA 4AEAA 1KC4A 4FAOE 1ERGA 2UWRA 1G6MA 1QKEA 1LXHA 2MJYA 3NEQA 1HC9A 1ONJA 2H62C 3NH7A 1HC9B 1LX5B 1F94A 2GOOB 4RUDA 1UG4A 4LFTA 1ZADA 1CTXA 2UX2A 1FSSB 1BXPA 3U74U 1CREA 1RGJA 2FD6U 4OM5A 2MUOA 1CHVS 2MUPA 1REWC 4FAOC 2J8BA 1F8UB 3PLCA 1KS6A 1FSCA 1PLOA 1CB9A 2MJ0A 1MAHF 1XT3A 3EBXA 3EVSC 4OM4A 2HLRA 1KTZB 1KL8A 2N99A 2QJAC 2VLWA 1LSIA 1W6BA 2H64C 1IQ9A 1NYUA 1HAAA 2MJ4A 3QB4B 4HQPF 1CCQA 2HLQA 2H5FA 1NTNA 5EBXA 1NYSA 2L03A 1KBAA 1S4YA 1CRFA 2MFAA 1CVOA 1IKCA 1HOYA 1BTEA 3KFDE 1LJZA 2NBTA 5DZ5A 4DO8A 2QJBC 1NXBA 4QTIU 5DU1A 1CDSA 2ERAA 2PJYB 1KBTA 2I9BE 2PJYC 1IDHA 1CDTA 5DO6A
chains in the Genus database with same CATH superfamily
5IMTD 3ERAA 2QC1A 1V6PA 2BTXA 1TXAA 1NEAA 2CRSA 1M9ZA 1RL5A 1CDRA 1IDGA 2LA1A 2L5SA 1VB0A 1YWHA 5IMYC 3NDSA 2H62D 2H64B 1KXIA 1ERAA 1QM7A 1ABTA 1NORA 1NTXA 1CODA 1I02A 1IDLA 2CCXA 1KBSA 2MHYA 1LXGA 1IJCA 1FRAA 3HH7A 3KFDI 2H8UA 1TXBA 1MR6A 2X8BB 4EY8B 4IYEA 2JVEA 2OFSA 6EBXA 1ES7B 3FEVA 1FF4A 4XJJA 4KSNA 2GOOC 2H7ZA 1FASA 4BIKB 1KFHA 2CRTA 1HAJA 4BDTB 1TGXA 2CTXA 4UY2C 3VTSA 1DRSA 1JE9A 1JBDA 3LAQU 1H0JA 2H7ZB 1TFSA 1B41B 1IDIA 2K3GA 1JGKA 2ABXA 1COEA 3BT2U 2CDXA 1IK8A 1CXNA 1CXOA 2LCRA 1L4WA 2QJ9C 3U73U 1QKDA 2BHIA 3BT1U 1CDQA 1KU6B 4P7UA 4ZQYA 1FFJA 2JQPA 4AEAA 1KC4A 4FAOE 1ERGA 2UWRA 1G6MA 1QKEA 1LXHA 2MJYA 3NEQA 1HC9A 1ONJA 2H62C 3NH7A 1HC9B 1LX5B 1F94A 2GOOB 4RUDA 1UG4A 4LFTA 1ZADA 1CTXA 2UX2A 1FSSB 1BXPA 3U74U 1CREA 1RGJA 2FD6U 4OM5A 2MUOA 1CHVS 2MUPA 1REWC 4FAOC 2J8BA 1F8UB 3PLCA 1KS6A 1FSCA 1PLOA 1CB9A 2MJ0A 1MAHF 1XT3A 3EBXA 3EVSC 4OM4A 2HLRA 1KTZB 1KL8A 2N99A 2QJAC 2VLWA 1LSIA 1W6BA 2H64C 1IQ9A 1NYUA 1HAAA 2MJ4A 3QB4B 4HQPF 1CCQA 2HLQA 2H5FA 1NTNA 5EBXA 1NYSA 2L03A 1KBAA 1S4YA 1CRFA 2MFAA 1CVOA 1IKCA 1HOYA 1BTEA 3KFDE 1LJZA 2NBTA 5DZ5A 4DO8A 2QJBC 1NXBA 4QTIU 5DU1A 1CDSA 2ERAA 2PJYB 1KBTA 2I9BE 2PJYC 1IDHA 1CDTA 5DO6A
chains in the Genus database with same CATH topology
5IMTD 3ERAA 2QC1A 1V6PA 2BTXA 1TXAA 1NEAA 2CRSA 1M9ZA 1RL5A 1CDRA 1IDGA 2LA1A 2L5SA 1VB0A 1YWHA 5IMYC 3NDSA 2H62D 2H64B 1KXIA 1ERAA 1QM7A 1ABTA 1NORA 1NTXA 1CODA 1I02A 1IDLA 2CCXA 1KBSA 2MHYA 1LXGA 1IJCA 1FRAA 3HH7A 3KFDI 2H8UA 1TXBA 1MR6A 2X8BB 4EY8B 4IYEA 2JVEA 2OFSA 6EBXA 1ES7B 3FEVA 1FF4A 4XJJA 4KSNA 2GOOC 2H7ZA 1FASA 4BIKB 1KFHA 2CRTA 1HAJA 4BDTB 1TGXA 2CTXA 4UY2C 3VTSA 1DRSA 1JE9A 1JBDA 3LAQU 1H0JA 2H7ZB 1TFSA 1B41B 1IDIA 2K3GA 1JGKA 2ABXA 1COEA 3BT2U 2CDXA 1IK8A 1CXNA 1CXOA 2LCRA 1L4WA 2QJ9C 3U73U 1QKDA 2BHIA 3BT1U 1CDQA 1KU6B 4P7UA 4ZQYA 1FFJA 2JQPA 4AEAA 1KC4A 4FAOE 1ERGA 2UWRA 1G6MA 1QKEA 1LXHA 2MJYA 3NEQA 1HC9A 1ONJA 2H62C 3NH7A 1HC9B 1LX5B 1F94A 2GOOB 4RUDA 1UG4A 4LFTA 1ZADA 1CTXA 2UX2A 1FSSB 1BXPA 3U74U 1CREA 1RGJA 2FD6U 4OM5A 2MUOA 1CHVS 2MUPA 1REWC 4FAOC 2J8BA 1F8UB 3PLCA 1KS6A 1FSCA 1PLOA 1CB9A 2MJ0A 1MAHF 1XT3A 3EBXA 3EVSC 4OM4A 2HLRA 1KTZB 1KL8A 2N99A 2QJAC 2VLWA 1LSIA 1W6BA 2H64C 1IQ9A 1NYUA 1HAAA 2MJ4A 3QB4B 4HQPF 1CCQA 2HLQA 2H5FA 1NTNA 5EBXA 1NYSA 2L03A 1KBAA 1S4YA 1CRFA 2MFAA 1CVOA 1IKCA 1HOYA 1BTEA 3KFDE 1LJZA 2NBTA 5DZ5A 4DO8A 2QJBC 1NXBA 4QTIU 5DU1A 1CDSA 2ERAA 2PJYB 1KBTA 2I9BE 2PJYC 1IDHA 1CDTA 5DO6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IMT D;  3ERA A;  2QC1 A;  1V6P A;  2BTX A;  1TXA A;  1NEA A;  2CRS A;  1M9Z A;  1RL5 A;  1CDR A;  1IDG A;  2LA1 A;  2L5S A;  1VB0 A;  1YWH A;  5IMY C;  3NDS A;  2H62 D;  2H64 B;  1KXI A;  1ERA A;  1QM7 A;  1ABT A;  1NOR A;  1NTX A;  1COD A;  1I02 A;  1IDL A;  2CCX A;  1KBS A;  2MHY A;  1LXG A;  1IJC A;  1FRA A;  3HH7 A;  3KFD I;  2H8U A;  1TXB A;  1MR6 A;  2X8B B;  4EY8 B;  4IYE A;  2JVE A;  2OFS A;  6EBX A;  1ES7 B;  3FEV A;  1FF4 A;  4XJJ A;  2GOO C;  2H7Z A;  1FAS A;  4BIK B;  1KFH A;  2CRT A;  1HAJ A;  4BDT B;  1TGX A;  2CTX A;  4UY2 C;  3VTS A;  1DRS A;  1JE9 A;  1JBD A;  3LAQ U;  1H0J A;  2H7Z B;  1TFS A;  1B41 B;  1IDI A;  2K3G A;  1JGK A;  2ABX A;  1COE A;  3BT2 U;  2CDX A;  1IK8 A;  1CXN A;  1CXO A;  2LCR A;  1L4W A;  2QJ9 C;  3U73 U;  1QKD A;  2BHI A;  3BT1 U;  1CDQ A;  1KU6 B;  4P7U A;  4ZQY A;  1FFJ A;  2JQP A;  4AEA A;  1KC4 A;  4FAO E;  1ERG A;  2UWR A;  1G6M A;  1QKE A;  1LXH A;  2MJY A;  3NEQ A;  1HC9 A;  1ONJ A;  2H62 C;  3NH7 A;  1HC9 B;  1LX5 B;  1F94 A;  2GOO B;  4RUD A;  1UG4 A;  4LFT A;  1ZAD A;  1CTX A;  2UX2 A;  1FSS B;  1BXP A;  3U74 U;  1CRE A;  1RGJ A;  2FD6 U;  4OM5 A;  2MUO A;  1CHV S;  2MUP A;  1REW C;  4FAO C;  2J8B A;  1F8U B;  3PLC A;  1KS6 A;  1FSC A;  1PLO A;  1CB9 A;  2MJ0 A;  1MAH F;  1XT3 A;  3EBX A;  3EVS C;  4OM4 A;  2HLR A;  1KTZ B;  1KL8 A;  2N99 A;  2QJA C;  2VLW A;  1LSI A;  1W6B A;  2H64 C;  1IQ9 A;  1NYU A;  1HAA A;  2MJ4 A;  3QB4 B;  4HQP F;  1CCQ A;  2HLQ A;  2H5F A;  1NTN A;  5EBX A;  1NYS A;  2L03 A;  1KBA A;  1S4Y A;  1CRF A;  2MFA A;  1CVO A;  1IKC A;  1HOY A;  1BTE A;  3KFD E;  1LJZ A;  2NBT A;  5DZ5 A;  4DO8 A;  2QJB C;  1NXB A;  4QTI U;  5DU1 A;  1CDS A;  2ERA A;  2PJY B;  1KBT A;  2I9B E;  2PJY C;  1IDH A;  1CDT A;  5DO6 A; 
#chains in the Genus database with same CATH topology
 5IMT D;  3ERA A;  2QC1 A;  1V6P A;  2BTX A;  1TXA A;  1NEA A;  2CRS A;  1M9Z A;  1RL5 A;  1CDR A;  1IDG A;  2LA1 A;  2L5S A;  1VB0 A;  1YWH A;  5IMY C;  3NDS A;  2H62 D;  2H64 B;  1KXI A;  1ERA A;  1QM7 A;  1ABT A;  1NOR A;  1NTX A;  1COD A;  1I02 A;  1IDL A;  2CCX A;  1KBS A;  2MHY A;  1LXG A;  1IJC A;  1FRA A;  3HH7 A;  3KFD I;  2H8U A;  1TXB A;  1MR6 A;  2X8B B;  4EY8 B;  4IYE A;  2JVE A;  2OFS A;  6EBX A;  1ES7 B;  3FEV A;  1FF4 A;  4XJJ A;  4KSN A;  2GOO C;  2H7Z A;  1FAS A;  4BIK B;  1KFH A;  2CRT A;  1HAJ A;  4BDT B;  1TGX A;  2CTX A;  4UY2 C;  3VTS A;  1DRS A;  1JE9 A;  1JBD A;  3LAQ U;  1H0J A;  2H7Z B;  1TFS A;  1B41 B;  1IDI A;  2K3G A;  1JGK A;  2ABX A;  1COE A;  3BT2 U;  2CDX A;  1IK8 A;  1CXN A;  1CXO A;  2LCR A;  1L4W A;  2QJ9 C;  3U73 U;  1QKD A;  2BHI A;  3BT1 U;  1CDQ A;  1KU6 B;  4P7U A;  4ZQY A;  1FFJ A;  2JQP A;  4AEA A;  1KC4 A;  4FAO E;  1ERG A;  2UWR A;  1G6M A;  1QKE A;  1LXH A;  2MJY A;  3NEQ A;  1HC9 A;  1ONJ A;  2H62 C;  3NH7 A;  1HC9 B;  1LX5 B;  1F94 A;  2GOO B;  4RUD A;  1UG4 A;  4LFT A;  1ZAD A;  1CTX A;  2UX2 A;  1FSS B;  1BXP A;  3U74 U;  1CRE A;  1RGJ A;  2FD6 U;  4OM5 A;  2MUO A;  1CHV S;  2MUP A;  1REW C;  4FAO C;  2J8B A;  1F8U B;  3PLC A;  1KS6 A;  1FSC A;  1PLO A;  1CB9 A;  2MJ0 A;  1MAH F;  1XT3 A;  3EBX A;  3EVS C;  4OM4 A;  2HLR A;  1KTZ B;  1KL8 A;  2N99 A;  2QJA C;  2VLW A;  1LSI A;  1W6B A;  2H64 C;  1IQ9 A;  1NYU A;  1HAA A;  2MJ4 A;  3QB4 B;  4HQP F;  1CCQ A;  2HLQ A;  2H5F A;  1NTN A;  5EBX A;  1NYS A;  2L03 A;  1KBA A;  1S4Y A;  1CRF A;  2MFA A;  1CVO A;  1IKC A;  1HOY A;  1BTE A;  3KFD E;  1LJZ A;  2NBT A;  5DZ5 A;  4DO8 A;  2QJB C;  1NXB A;  4QTI U;  5DU1 A;  1CDS A;  2ERA A;  2PJY B;  1KBT A;  2I9B E;  2PJY C;  1IDH A;  1CDT A;  5DO6 A; 
#chains in the Genus database with same CATH homology
 5IMT D;  3ERA A;  2QC1 A;  1V6P A;  2BTX A;  1TXA A;  1NEA A;  2CRS A;  1M9Z A;  1RL5 A;  1CDR A;  1IDG A;  2LA1 A;  2L5S A;  1VB0 A;  1YWH A;  5IMY C;  3NDS A;  2H62 D;  2H64 B;  1KXI A;  1ERA A;  1QM7 A;  1ABT A;  1NOR A;  1NTX A;  1COD A;  1I02 A;  1IDL A;  2CCX A;  1KBS A;  2MHY A;  1LXG A;  1IJC A;  1FRA A;  3HH7 A;  3KFD I;  2H8U A;  1TXB A;  1MR6 A;  2X8B B;  4EY8 B;  4IYE A;  2JVE A;  2OFS A;  6EBX A;  1ES7 B;  3FEV A;  1FF4 A;  4XJJ A;  4KSN A;  2GOO C;  2H7Z A;  1FAS A;  4BIK B;  1KFH A;  2CRT A;  1HAJ A;  4BDT B;  1TGX A;  2CTX A;  4UY2 C;  3VTS A;  1DRS A;  1JE9 A;  1JBD A;  3LAQ U;  1H0J A;  2H7Z B;  1TFS A;  1B41 B;  1IDI A;  2K3G A;  1JGK A;  2ABX A;  1COE A;  3BT2 U;  2CDX A;  1IK8 A;  1CXN A;  1CXO A;  2LCR A;  1L4W A;  2QJ9 C;  3U73 U;  1QKD A;  2BHI A;  3BT1 U;  1CDQ A;  1KU6 B;  4P7U A;  4ZQY A;  1FFJ A;  2JQP A;  4AEA A;  1KC4 A;  4FAO E;  1ERG A;  2UWR A;  1G6M A;  1QKE A;  1LXH A;  2MJY A;  3NEQ A;  1HC9 A;  1ONJ A;  2H62 C;  3NH7 A;  1HC9 B;  1LX5 B;  1F94 A;  2GOO B;  4RUD A;  1UG4 A;  4LFT A;  1ZAD A;  1CTX A;  2UX2 A;  1FSS B;  1BXP A;  3U74 U;  1CRE A;  1RGJ A;  2FD6 U;  4OM5 A;  2MUO A;  1CHV S;  2MUP A;  1REW C;  4FAO C;  2J8B A;  1F8U B;  3PLC A;  1KS6 A;  1FSC A;  1PLO A;  1CB9 A;  2MJ0 A;  1MAH F;  1XT3 A;  3EBX A;  3EVS C;  4OM4 A;  2HLR A;  1KTZ B;  1KL8 A;  2N99 A;  2QJA C;  2VLW A;  1LSI A;  1W6B A;  2H64 C;  1IQ9 A;  1NYU A;  1HAA A;  2MJ4 A;  3QB4 B;  4HQP F;  1CCQ A;  2HLQ A;  2H5F A;  1NTN A;  5EBX A;  1NYS A;  2L03 A;  1KBA A;  1S4Y A;  1CRF A;  2MFA A;  1CVO A;  1IKC A;  1HOY A;  1BTE A;  3KFD E;  1LJZ A;  2NBT A;  5DZ5 A;  4DO8 A;  2QJB C;  1NXB A;  4QTI U;  5DU1 A;  1CDS A;  2ERA A;  2PJY B;  1KBT A;  2I9B E;  2PJY C;  1IDH A;  1CDT A;  5DO6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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