1KTZB

Crystal structure of the human tgf-beta type ii receptor extracellular domain in complex with tgf-beta3
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
106
structure length
106
Chain Sequence
PQLCKFCDVRFSTCDNQKSCMSNCSITSICEKPQEVCVAVWRKNDENITLETVCHDPKLPYHDFILEDAASPKCIMKEKKKPGETFFMCSCSSDECNDNIIFSEEY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the human TbetaR2 ectodomain--TGF-beta3 complex.
pubmed rcsb
molecule tags Cytokine/cytokine receptor
source organism Homo sapiens
molecule keywords TRANSFORMING GROWTH FACTOR BETA 3
total genus 23
structure length 106
sequence length 106
ec nomenclature ec 2.7.11.30: Receptor protein serine/threonine kinase.
pdb deposition date 2002-01-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF08917 ecTbetaR2 Transforming growth factor beta receptor 2 ectodomain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 1ktzB00
1CODA 1FRAA 1M9ZA 1NORA 1KBAA 2I9BE 5DU1A 3NH7A 3VTSA 2MJYA 3NDSA 1ERGA 1DRSA 1CDSA 1NTNA 1QM7A 1ZADA 5DZ5A 5IMYC 4EY8B 1KBTA 3U73U 2JQPA 1IJCA 1NEAA 1KL8A 1CDQA 1LJZA 1TXAA 1NTXA 1IK8A 3LAQU 4OM5A 1TFSA 1RGJA 2H62D 2JVEA 2ERAA 4DO8A 2HLRA 2CCXA 2X8BB 3HH7A 1CHVS 1NXBA 2NBTA 1XT3A 1LSIA 2K3GA 3ERAA 1HC9A 1ERAA 1CXNA 4HQPF 2CDXA 1TGXA 1CB9A 2ABXA 4XJJA 2FD6U 2J8BA 2QC1A 1UG4A 1QKEA 2H7ZB 1KBSA 1BXPA 3EBXA 2BTXA 4AEAA 2LA1A 2GOOB 2UX2A 4OM4A 1QKDA 2LCRA 3FEVA 1MR6A 2H64C 1CVOA 2QJBC 2QJ9C 1FASA 1HAJA 4RUDA 4QTIU 1V6PA 4BIKB 1L4WA 1ONJA 3KFDE 2CRTA 3PLCA 1KFHA 1ABTA 2MJ0A 3NEQA 1CCQA 2MHYA 3U74U 1IKCA 2N99A 1IQ9A 2MUOA 1KS6A 1F94A 1KTZB 1PLOA 2PJYB 1FSCA 5DO6A 3QB4B 1IDGA 1BTEA 1H0JA 1RL5A 4FAOE 2GOOC 2H7ZA 1F8UB 1KU6B 2CRSA 1LX5B 2H8UA 3BT2U 2H62C 1NYSA 4P7UA 4UY2C 1CDRA 1IDHA 2MFAA 5EBXA 1CTXA 1IDLA 1CDTA 1CREA 4BDTB 1KC4A 1FSSB 2VLWA 1JBDA 2PJYC 2CTXA 2L5SA 2UWRA 4IYEA 5IMTD 1REWC 1VB0A 1W6BA 1NYUA 1JGKA 1CRFA 3EVSC 1ES7B 1FF4A 1HOYA 2HLQA 2L03A 2QJAC 4FAOC 1LXGA 1JE9A 4ZQYA 1LXHA 1B41B 2H5FA 1YWHA 2MUPA 1CXOA 1HAAA 6EBXA 2H64B 1G6MA 2OFSA 4LFTA 1MAHF 2MJ4A 1KXIA 2BHIA 1IDIA 1S4YA 1I02A 1TXBA 1FFJA 1COEA 1HC9B 3KFDI 3BT1U
chains in the Genus database with same CATH superfamily
1CODA 1FRAA 1M9ZA 1NORA 1KBAA 2I9BE 5DU1A 3NH7A 3VTSA 2MJYA 3NDSA 1ERGA 1DRSA 1CDSA 1NTNA 1QM7A 1ZADA 5DZ5A 5IMYC 4EY8B 1KBTA 3U73U 2JQPA 1IJCA 1NEAA 1KL8A 1CDQA 1LJZA 1TXAA 1NTXA 1IK8A 3LAQU 4OM5A 1TFSA 1RGJA 2H62D 2JVEA 2ERAA 4DO8A 2HLRA 2CCXA 2X8BB 3HH7A 1CHVS 1NXBA 2NBTA 1XT3A 1LSIA 2K3GA 3ERAA 1HC9A 1ERAA 1CXNA 4HQPF 2CDXA 1TGXA 1CB9A 2ABXA 4XJJA 2FD6U 2J8BA 2QC1A 1UG4A 1QKEA 2H7ZB 1KBSA 1BXPA 3EBXA 2BTXA 4AEAA 2LA1A 2GOOB 2UX2A 4OM4A 1QKDA 2LCRA 3FEVA 1MR6A 2H64C 1CVOA 2QJBC 2QJ9C 1FASA 1HAJA 4RUDA 4QTIU 1V6PA 4BIKB 1L4WA 1ONJA 3KFDE 2CRTA 3PLCA 1KFHA 1ABTA 2MJ0A 3NEQA 1CCQA 2MHYA 3U74U 1IKCA 2N99A 4KSNA 1IQ9A 2MUOA 1KS6A 1F94A 1KTZB 1PLOA 2PJYB 1FSCA 5DO6A 3QB4B 1IDGA 1BTEA 1H0JA 1RL5A 4FAOE 2GOOC 2H7ZA 1F8UB 1KU6B 2CRSA 1LX5B 2H8UA 3BT2U 2H62C 1NYSA 4P7UA 4UY2C 1CDRA 1IDHA 2MFAA 5EBXA 1CTXA 1IDLA 1CDTA 1CREA 4BDTB 1KC4A 1FSSB 2VLWA 1JBDA 2PJYC 2CTXA 2L5SA 2UWRA 4IYEA 5IMTD 1REWC 1VB0A 1W6BA 1NYUA 1JGKA 1CRFA 3EVSC 1ES7B 1FF4A 1HOYA 2HLQA 2L03A 2QJAC 4FAOC 1LXGA 1JE9A 4ZQYA 1LXHA 1B41B 2H5FA 1YWHA 2MUPA 1CXOA 1HAAA 6EBXA 2H64B 1G6MA 2OFSA 4LFTA 1MAHF 2MJ4A 1KXIA 2BHIA 1IDIA 1S4YA 1I02A 1TXBA 1FFJA 1COEA 1HC9B 3KFDI 3BT1U
chains in the Genus database with same CATH topology
1CODA 1FRAA 1M9ZA 1NORA 1KBAA 2I9BE 5DU1A 3NH7A 3VTSA 2MJYA 3NDSA 1ERGA 1DRSA 1CDSA 1NTNA 1QM7A 1ZADA 5DZ5A 5IMYC 4EY8B 1KBTA 3U73U 2JQPA 1IJCA 1NEAA 1KL8A 1CDQA 1LJZA 1TXAA 1NTXA 1IK8A 3LAQU 4OM5A 1TFSA 1RGJA 2H62D 2JVEA 2ERAA 4DO8A 2HLRA 2CCXA 2X8BB 3HH7A 1CHVS 1NXBA 2NBTA 1XT3A 1LSIA 2K3GA 3ERAA 1HC9A 1ERAA 1CXNA 4HQPF 2CDXA 1TGXA 1CB9A 2ABXA 4XJJA 2FD6U 2J8BA 2QC1A 1UG4A 1QKEA 2H7ZB 1KBSA 1BXPA 3EBXA 2BTXA 4AEAA 2LA1A 2GOOB 2UX2A 4OM4A 1QKDA 2LCRA 3FEVA 1MR6A 2H64C 1CVOA 2QJBC 2QJ9C 1FASA 1HAJA 4RUDA 4QTIU 1V6PA 4BIKB 1L4WA 1ONJA 3KFDE 2CRTA 3PLCA 1KFHA 1ABTA 2MJ0A 3NEQA 1CCQA 2MHYA 3U74U 1IKCA 2N99A 4KSNA 1IQ9A 2MUOA 1KS6A 1F94A 1KTZB 1PLOA 2PJYB 1FSCA 5DO6A 3QB4B 1IDGA 1BTEA 1H0JA 1RL5A 4FAOE 2GOOC 2H7ZA 1F8UB 1KU6B 2CRSA 1LX5B 2H8UA 3BT2U 2H62C 1NYSA 4P7UA 4UY2C 1CDRA 1IDHA 2MFAA 5EBXA 1CTXA 1IDLA 1CDTA 1CREA 4BDTB 1KC4A 1FSSB 2VLWA 1JBDA 2PJYC 2CTXA 2L5SA 2UWRA 4IYEA 5IMTD 1REWC 1VB0A 1W6BA 1NYUA 1JGKA 1CRFA 3EVSC 1ES7B 1FF4A 1HOYA 2HLQA 2L03A 2QJAC 4FAOC 1LXGA 1JE9A 4ZQYA 1LXHA 1B41B 2H5FA 1YWHA 2MUPA 1CXOA 1HAAA 6EBXA 2H64B 1G6MA 2OFSA 4LFTA 1MAHF 2MJ4A 1KXIA 2BHIA 1IDIA 1S4YA 1I02A 1TXBA 1FFJA 1COEA 1HC9B 3KFDI 3BT1U
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1COD A;  1FRA A;  1M9Z A;  1NOR A;  1KBA A;  2I9B E;  5DU1 A;  3NH7 A;  3VTS A;  2MJY A;  3NDS A;  1ERG A;  1DRS A;  1CDS A;  1NTN A;  1QM7 A;  1ZAD A;  5DZ5 A;  5IMY C;  4EY8 B;  1KBT A;  3U73 U;  2JQP A;  1IJC A;  1NEA A;  1KL8 A;  1CDQ A;  1LJZ A;  1TXA A;  1NTX A;  1IK8 A;  3LAQ U;  4OM5 A;  1TFS A;  1RGJ A;  2H62 D;  2JVE A;  2ERA A;  4DO8 A;  2HLR A;  2CCX A;  2X8B B;  3HH7 A;  1CHV S;  1NXB A;  2NBT A;  1XT3 A;  1LSI A;  2K3G A;  3ERA A;  1HC9 A;  1ERA A;  1CXN A;  4HQP F;  2CDX A;  1TGX A;  1CB9 A;  2ABX A;  4XJJ A;  2FD6 U;  2J8B A;  2QC1 A;  1UG4 A;  1QKE A;  2H7Z B;  1KBS A;  1BXP A;  3EBX A;  2BTX A;  4AEA A;  2LA1 A;  2GOO B;  2UX2 A;  4OM4 A;  1QKD A;  2LCR A;  3FEV A;  1MR6 A;  2H64 C;  1CVO A;  2QJB C;  2QJ9 C;  1FAS A;  1HAJ A;  4RUD A;  4QTI U;  1V6P A;  4BIK B;  1L4W A;  1ONJ A;  3KFD E;  2CRT A;  3PLC A;  1KFH A;  1ABT A;  2MJ0 A;  3NEQ A;  1CCQ A;  2MHY A;  3U74 U;  1IKC A;  2N99 A;  1IQ9 A;  2MUO A;  1KS6 A;  1F94 A;  1KTZ B;  1PLO A;  2PJY B;  1FSC A;  5DO6 A;  3QB4 B;  1IDG A;  1BTE A;  1H0J A;  1RL5 A;  4FAO E;  2GOO C;  2H7Z A;  1F8U B;  1KU6 B;  2CRS A;  1LX5 B;  2H8U A;  3BT2 U;  2H62 C;  1NYS A;  4P7U A;  4UY2 C;  1CDR A;  1IDH A;  2MFA A;  5EBX A;  1CTX A;  1IDL A;  1CDT A;  1CRE A;  4BDT B;  1KC4 A;  1FSS B;  2VLW A;  1JBD A;  2PJY C;  2CTX A;  2L5S A;  2UWR A;  4IYE A;  5IMT D;  1REW C;  1VB0 A;  1W6B A;  1NYU A;  1JGK A;  1CRF A;  3EVS C;  1ES7 B;  1FF4 A;  1HOY A;  2HLQ A;  2L03 A;  2QJA C;  4FAO C;  1LXG A;  1JE9 A;  4ZQY A;  1LXH A;  1B41 B;  2H5F A;  1YWH A;  2MUP A;  1CXO A;  1HAA A;  6EBX A;  2H64 B;  1G6M A;  2OFS A;  4LFT A;  1MAH F;  2MJ4 A;  1KXI A;  2BHI A;  1IDI A;  1S4Y A;  1I02 A;  1TXB A;  1FFJ A;  1COE A;  1HC9 B;  3KFD I;  3BT1 U; 
#chains in the Genus database with same CATH topology
 1COD A;  1FRA A;  1M9Z A;  1NOR A;  1KBA A;  2I9B E;  5DU1 A;  3NH7 A;  3VTS A;  2MJY A;  3NDS A;  1ERG A;  1DRS A;  1CDS A;  1NTN A;  1QM7 A;  1ZAD A;  5DZ5 A;  5IMY C;  4EY8 B;  1KBT A;  3U73 U;  2JQP A;  1IJC A;  1NEA A;  1KL8 A;  1CDQ A;  1LJZ A;  1TXA A;  1NTX A;  1IK8 A;  3LAQ U;  4OM5 A;  1TFS A;  1RGJ A;  2H62 D;  2JVE A;  2ERA A;  4DO8 A;  2HLR A;  2CCX A;  2X8B B;  3HH7 A;  1CHV S;  1NXB A;  2NBT A;  1XT3 A;  1LSI A;  2K3G A;  3ERA A;  1HC9 A;  1ERA A;  1CXN A;  4HQP F;  2CDX A;  1TGX A;  1CB9 A;  2ABX A;  4XJJ A;  2FD6 U;  2J8B A;  2QC1 A;  1UG4 A;  1QKE A;  2H7Z B;  1KBS A;  1BXP A;  3EBX A;  2BTX A;  4AEA A;  2LA1 A;  2GOO B;  2UX2 A;  4OM4 A;  1QKD A;  2LCR A;  3FEV A;  1MR6 A;  2H64 C;  1CVO A;  2QJB C;  2QJ9 C;  1FAS A;  1HAJ A;  4RUD A;  4QTI U;  1V6P A;  4BIK B;  1L4W A;  1ONJ A;  3KFD E;  2CRT A;  3PLC A;  1KFH A;  1ABT A;  2MJ0 A;  3NEQ A;  1CCQ A;  2MHY A;  3U74 U;  1IKC A;  2N99 A;  4KSN A;  1IQ9 A;  2MUO A;  1KS6 A;  1F94 A;  1KTZ B;  1PLO A;  2PJY B;  1FSC A;  5DO6 A;  3QB4 B;  1IDG A;  1BTE A;  1H0J A;  1RL5 A;  4FAO E;  2GOO C;  2H7Z A;  1F8U B;  1KU6 B;  2CRS A;  1LX5 B;  2H8U A;  3BT2 U;  2H62 C;  1NYS A;  4P7U A;  4UY2 C;  1CDR A;  1IDH A;  2MFA A;  5EBX A;  1CTX A;  1IDL A;  1CDT A;  1CRE A;  4BDT B;  1KC4 A;  1FSS B;  2VLW A;  1JBD A;  2PJY C;  2CTX A;  2L5S A;  2UWR A;  4IYE A;  5IMT D;  1REW C;  1VB0 A;  1W6B A;  1NYU A;  1JGK A;  1CRF A;  3EVS C;  1ES7 B;  1FF4 A;  1HOY A;  2HLQ A;  2L03 A;  2QJA C;  4FAO C;  1LXG A;  1JE9 A;  4ZQY A;  1LXH A;  1B41 B;  2H5F A;  1YWH A;  2MUP A;  1CXO A;  1HAA A;  6EBX A;  2H64 B;  1G6M A;  2OFS A;  4LFT A;  1MAH F;  2MJ4 A;  1KXI A;  2BHI A;  1IDI A;  1S4Y A;  1I02 A;  1TXB A;  1FFJ A;  1COE A;  1HC9 B;  3KFD I;  3BT1 U; 
#chains in the Genus database with same CATH homology
 1COD A;  1FRA A;  1M9Z A;  1NOR A;  1KBA A;  2I9B E;  5DU1 A;  3NH7 A;  3VTS A;  2MJY A;  3NDS A;  1ERG A;  1DRS A;  1CDS A;  1NTN A;  1QM7 A;  1ZAD A;  5DZ5 A;  5IMY C;  4EY8 B;  1KBT A;  3U73 U;  2JQP A;  1IJC A;  1NEA A;  1KL8 A;  1CDQ A;  1LJZ A;  1TXA A;  1NTX A;  1IK8 A;  3LAQ U;  4OM5 A;  1TFS A;  1RGJ A;  2H62 D;  2JVE A;  2ERA A;  4DO8 A;  2HLR A;  2CCX A;  2X8B B;  3HH7 A;  1CHV S;  1NXB A;  2NBT A;  1XT3 A;  1LSI A;  2K3G A;  3ERA A;  1HC9 A;  1ERA A;  1CXN A;  4HQP F;  2CDX A;  1TGX A;  1CB9 A;  2ABX A;  4XJJ A;  2FD6 U;  2J8B A;  2QC1 A;  1UG4 A;  1QKE A;  2H7Z B;  1KBS A;  1BXP A;  3EBX A;  2BTX A;  4AEA A;  2LA1 A;  2GOO B;  2UX2 A;  4OM4 A;  1QKD A;  2LCR A;  3FEV A;  1MR6 A;  2H64 C;  1CVO A;  2QJB C;  2QJ9 C;  1FAS A;  1HAJ A;  4RUD A;  4QTI U;  1V6P A;  4BIK B;  1L4W A;  1ONJ A;  3KFD E;  2CRT A;  3PLC A;  1KFH A;  1ABT A;  2MJ0 A;  3NEQ A;  1CCQ A;  2MHY A;  3U74 U;  1IKC A;  2N99 A;  4KSN A;  1IQ9 A;  2MUO A;  1KS6 A;  1F94 A;  1KTZ B;  1PLO A;  2PJY B;  1FSC A;  5DO6 A;  3QB4 B;  1IDG A;  1BTE A;  1H0J A;  1RL5 A;  4FAO E;  2GOO C;  2H7Z A;  1F8U B;  1KU6 B;  2CRS A;  1LX5 B;  2H8U A;  3BT2 U;  2H62 C;  1NYS A;  4P7U A;  4UY2 C;  1CDR A;  1IDH A;  2MFA A;  5EBX A;  1CTX A;  1IDL A;  1CDT A;  1CRE A;  4BDT B;  1KC4 A;  1FSS B;  2VLW A;  1JBD A;  2PJY C;  2CTX A;  2L5S A;  2UWR A;  4IYE A;  5IMT D;  1REW C;  1VB0 A;  1W6B A;  1NYU A;  1JGK A;  1CRF A;  3EVS C;  1ES7 B;  1FF4 A;  1HOY A;  2HLQ A;  2L03 A;  2QJA C;  4FAO C;  1LXG A;  1JE9 A;  4ZQY A;  1LXH A;  1B41 B;  2H5F A;  1YWH A;  2MUP A;  1CXO A;  1HAA A;  6EBX A;  2H64 B;  1G6M A;  2OFS A;  4LFT A;  1MAH F;  2MJ4 A;  1KXI A;  2BHI A;  1IDI A;  1S4Y A;  1I02 A;  1TXB A;  1FFJ A;  1COE A;  1HC9 B;  3KFD I;  3BT1 U; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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