1KU6B

Fasciculin 2-mouse acetylcholinesterase complex
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
61
structure length
61
Chain Sequence
TMCYSHTTTSRAILTNCGENSCYRKSRRHPPKMVLGRGCGCPPGDDNLEVKCCTSPDKCNY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site.
pubmed doi rcsb
molecule tags Hydrolase/toxin
source organism Mus musculus
molecule keywords ACETYLCHOLINESTERASE
total genus 10
structure length 61
sequence length 61
ec nomenclature
pdb deposition date 2002-01-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 1ku6B00
5DZ5A 1FFJA 4EY8B 2JQPA 4QTIU 2QC1A 1CDRA 1KC4A 4FAOC 1G6MA 2UX2A 1CXNA 1NORA 3NDSA 1VB0A 2BHIA 1NTNA 5IMYC 2CRTA 4BDTB 1FSCA 1COEA 1LXHA 3HH7A 1DRSA 1M9ZA 3EBXA 1CXOA 1HC9A 2UWRA 2PJYB 1CDTA 2QJBC 1HOYA 4AEAA 2NBTA 1IDGA 1TFSA 4XJJA 1YWHA 1NXBA 1LJZA 6EBXA 1W6BA 2ABXA 2L5SA 2MJYA 2MUPA 1TXBA 1JE9A 1KU6B 1HAJA 1ES7B 4OM4A 3KFDE 2CRSA 1CB9A 3LAQU 1ERAA 1PLOA 1TXAA 1BTEA 1CREA 1JBDA 3ERAA 1KFHA 2I9BE 2J8BA 1I02A 4OM5A 1CDSA 3FEVA 1KBAA 1S4YA 2GOOC 1MAHF 5EBXA 2H62D 1H0JA 2X8BB 4UY2C 1CODA 1LX5B 1NTXA 2ERAA 1TGXA 2N99A 2CCXA 4P7UA 4FAOE 1NYUA 5IMTD 2MFAA 3PLCA 4ZQYA 3NEQA 1FF4A 4BIKB 1CRFA 3KFDI 1JGKA 2MUOA 1F8UB 2OFSA 2HLQA 2HLRA 1KS6A 1ABTA 2H62C 1KBTA 1UG4A 3VTSA 2LA1A 3EVSC 1CTXA 1NEAA 3U74U 1CHVS 1ZADA 1FASA 1KL8A 2H64C 1FRAA 2H7ZB 2MJ0A 3BT2U 1IDLA 1KBSA 1IDIA 1CVOA 1CDQA 2QJAC 2H8UA 3BT1U 2VLWA 1IKCA 3U73U 1LSIA 1RGJA 2BTXA 2H5FA 2FD6U 3NH7A 2CDXA 2L03A 2K3GA 2CTXA 2MJ4A 1REWC 1HAAA 4DO8A 1CCQA 2JVEA 1HC9B 2GOOB 1BXPA 1QKEA 2H64B 1ONJA 1F94A 1NYSA 1V6PA 2MHYA 1QM7A 4HQPF 1IJCA 1B41B 1L4WA 1IDHA 3QB4B 5DU1A 1IQ9A 1FSSB 1RL5A 2QJ9C 5DO6A 4RUDA 1KXIA 1LXGA 1KTZB 1IK8A 1QKDA 4LFTA 1MR6A 1XT3A 2LCRA 1ERGA 2PJYC 2H7ZA 4IYEA
chains in the Genus database with same CATH superfamily
5DZ5A 1FFJA 4EY8B 2JQPA 4QTIU 2QC1A 1CDRA 1KC4A 4FAOC 1G6MA 2UX2A 1CXNA 1NORA 3NDSA 1VB0A 2BHIA 1NTNA 5IMYC 2CRTA 4BDTB 1FSCA 1COEA 1LXHA 3HH7A 1DRSA 1M9ZA 3EBXA 1CXOA 1HC9A 2UWRA 2PJYB 1CDTA 2QJBC 1HOYA 4AEAA 2NBTA 1IDGA 1TFSA 4XJJA 1YWHA 4KSNA 1NXBA 1LJZA 6EBXA 1W6BA 2ABXA 2L5SA 2MJYA 2MUPA 1TXBA 1JE9A 1KU6B 1HAJA 1ES7B 4OM4A 3KFDE 2CRSA 1CB9A 3LAQU 1ERAA 1PLOA 1TXAA 1BTEA 1CREA 1JBDA 3ERAA 1KFHA 2I9BE 2J8BA 1I02A 4OM5A 1CDSA 3FEVA 1KBAA 1S4YA 2GOOC 1MAHF 5EBXA 2H62D 1H0JA 2X8BB 4UY2C 1CODA 1LX5B 1NTXA 2ERAA 1TGXA 2N99A 2CCXA 4P7UA 4FAOE 1NYUA 5IMTD 2MFAA 3PLCA 4ZQYA 3NEQA 1FF4A 4BIKB 1CRFA 3KFDI 1JGKA 2MUOA 1F8UB 2OFSA 2HLQA 2HLRA 1KS6A 1ABTA 2H62C 1KBTA 1UG4A 3VTSA 2LA1A 3EVSC 1CTXA 1NEAA 3U74U 1CHVS 1ZADA 1FASA 1KL8A 2H64C 1FRAA 2H7ZB 2MJ0A 3BT2U 1IDLA 1KBSA 1IDIA 1CVOA 1CDQA 2QJAC 2H8UA 3BT1U 2VLWA 1IKCA 3U73U 1LSIA 1RGJA 2BTXA 2H5FA 2FD6U 3NH7A 2CDXA 2L03A 2K3GA 2CTXA 2MJ4A 1REWC 1HAAA 4DO8A 1CCQA 2JVEA 1HC9B 2GOOB 1BXPA 1QKEA 2H64B 1ONJA 1F94A 1NYSA 1V6PA 2MHYA 1QM7A 4HQPF 1IJCA 1B41B 1L4WA 1IDHA 3QB4B 5DU1A 1IQ9A 1FSSB 1RL5A 2QJ9C 5DO6A 4RUDA 1KXIA 1LXGA 1KTZB 1IK8A 1QKDA 4LFTA 1MR6A 1XT3A 2LCRA 1ERGA 2PJYC 2H7ZA 4IYEA
chains in the Genus database with same CATH topology
5DZ5A 1FFJA 4EY8B 2JQPA 4QTIU 2QC1A 1CDRA 1KC4A 4FAOC 1G6MA 2UX2A 1CXNA 1NORA 3NDSA 1VB0A 2BHIA 1NTNA 5IMYC 2CRTA 4BDTB 1FSCA 1COEA 1LXHA 3HH7A 1DRSA 1M9ZA 3EBXA 1CXOA 1HC9A 2UWRA 2PJYB 1CDTA 2QJBC 1HOYA 4AEAA 2NBTA 1IDGA 1TFSA 4XJJA 1YWHA 4KSNA 1NXBA 1LJZA 6EBXA 1W6BA 2ABXA 2L5SA 2MJYA 2MUPA 1TXBA 1JE9A 1KU6B 1HAJA 1ES7B 4OM4A 3KFDE 2CRSA 1CB9A 3LAQU 1ERAA 1PLOA 1TXAA 1BTEA 1CREA 1JBDA 3ERAA 1KFHA 2I9BE 2J8BA 1I02A 4OM5A 1CDSA 3FEVA 1KBAA 1S4YA 2GOOC 1MAHF 5EBXA 2H62D 1H0JA 2X8BB 4UY2C 1CODA 1LX5B 1NTXA 2ERAA 1TGXA 2N99A 2CCXA 4P7UA 4FAOE 1NYUA 5IMTD 2MFAA 3PLCA 4ZQYA 3NEQA 1FF4A 4BIKB 1CRFA 3KFDI 1JGKA 2MUOA 1F8UB 2OFSA 2HLQA 2HLRA 1KS6A 1ABTA 2H62C 1KBTA 1UG4A 3VTSA 2LA1A 3EVSC 1CTXA 1NEAA 3U74U 1CHVS 1ZADA 1FASA 1KL8A 2H64C 1FRAA 2H7ZB 2MJ0A 3BT2U 1IDLA 1KBSA 1IDIA 1CVOA 1CDQA 2QJAC 2H8UA 3BT1U 2VLWA 1IKCA 3U73U 1LSIA 1RGJA 2BTXA 2H5FA 2FD6U 3NH7A 2CDXA 2L03A 2K3GA 2CTXA 2MJ4A 1REWC 1HAAA 4DO8A 1CCQA 2JVEA 1HC9B 2GOOB 1BXPA 1QKEA 2H64B 1ONJA 1F94A 1NYSA 1V6PA 2MHYA 1QM7A 4HQPF 1IJCA 1B41B 1L4WA 1IDHA 3QB4B 5DU1A 1IQ9A 1FSSB 1RL5A 2QJ9C 5DO6A 4RUDA 1KXIA 1LXGA 1KTZB 1IK8A 1QKDA 4LFTA 1MR6A 1XT3A 2LCRA 1ERGA 2PJYC 2H7ZA 4IYEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DZ5 A;  1FFJ A;  4EY8 B;  2JQP A;  4QTI U;  2QC1 A;  1CDR A;  1KC4 A;  4FAO C;  1G6M A;  2UX2 A;  1CXN A;  1NOR A;  3NDS A;  1VB0 A;  2BHI A;  1NTN A;  5IMY C;  2CRT A;  4BDT B;  1FSC A;  1COE A;  1LXH A;  3HH7 A;  1DRS A;  1M9Z A;  3EBX A;  1CXO A;  1HC9 A;  2UWR A;  2PJY B;  1CDT A;  2QJB C;  1HOY A;  4AEA A;  2NBT A;  1IDG A;  1TFS A;  4XJJ A;  1YWH A;  1NXB A;  1LJZ A;  6EBX A;  1W6B A;  2ABX A;  2L5S A;  2MJY A;  2MUP A;  1TXB A;  1JE9 A;  1KU6 B;  1HAJ A;  1ES7 B;  4OM4 A;  3KFD E;  2CRS A;  1CB9 A;  3LAQ U;  1ERA A;  1PLO A;  1TXA A;  1BTE A;  1CRE A;  1JBD A;  3ERA A;  1KFH A;  2I9B E;  2J8B A;  1I02 A;  4OM5 A;  1CDS A;  3FEV A;  1KBA A;  1S4Y A;  2GOO C;  1MAH F;  5EBX A;  2H62 D;  1H0J A;  2X8B B;  4UY2 C;  1COD A;  1LX5 B;  1NTX A;  2ERA A;  1TGX A;  2N99 A;  2CCX A;  4P7U A;  4FAO E;  1NYU A;  5IMT D;  2MFA A;  3PLC A;  4ZQY A;  3NEQ A;  1FF4 A;  4BIK B;  1CRF A;  3KFD I;  1JGK A;  2MUO A;  1F8U B;  2OFS A;  2HLQ A;  2HLR A;  1KS6 A;  1ABT A;  2H62 C;  1KBT A;  1UG4 A;  3VTS A;  2LA1 A;  3EVS C;  1CTX A;  1NEA A;  3U74 U;  1CHV S;  1ZAD A;  1FAS A;  1KL8 A;  2H64 C;  1FRA A;  2H7Z B;  2MJ0 A;  3BT2 U;  1IDL A;  1KBS A;  1IDI A;  1CVO A;  1CDQ A;  2QJA C;  2H8U A;  3BT1 U;  2VLW A;  1IKC A;  3U73 U;  1LSI A;  1RGJ A;  2BTX A;  2H5F A;  2FD6 U;  3NH7 A;  2CDX A;  2L03 A;  2K3G A;  2CTX A;  2MJ4 A;  1REW C;  1HAA A;  4DO8 A;  1CCQ A;  2JVE A;  1HC9 B;  2GOO B;  1BXP A;  1QKE A;  2H64 B;  1ONJ A;  1F94 A;  1NYS A;  1V6P A;  2MHY A;  1QM7 A;  4HQP F;  1IJC A;  1B41 B;  1L4W A;  1IDH A;  3QB4 B;  5DU1 A;  1IQ9 A;  1FSS B;  1RL5 A;  2QJ9 C;  5DO6 A;  4RUD A;  1KXI A;  1LXG A;  1KTZ B;  1IK8 A;  1QKD A;  4LFT A;  1MR6 A;  1XT3 A;  2LCR A;  1ERG A;  2PJY C;  2H7Z A;  4IYE A; 
#chains in the Genus database with same CATH topology
 5DZ5 A;  1FFJ A;  4EY8 B;  2JQP A;  4QTI U;  2QC1 A;  1CDR A;  1KC4 A;  4FAO C;  1G6M A;  2UX2 A;  1CXN A;  1NOR A;  3NDS A;  1VB0 A;  2BHI A;  1NTN A;  5IMY C;  2CRT A;  4BDT B;  1FSC A;  1COE A;  1LXH A;  3HH7 A;  1DRS A;  1M9Z A;  3EBX A;  1CXO A;  1HC9 A;  2UWR A;  2PJY B;  1CDT A;  2QJB C;  1HOY A;  4AEA A;  2NBT A;  1IDG A;  1TFS A;  4XJJ A;  1YWH A;  4KSN A;  1NXB A;  1LJZ A;  6EBX A;  1W6B A;  2ABX A;  2L5S A;  2MJY A;  2MUP A;  1TXB A;  1JE9 A;  1KU6 B;  1HAJ A;  1ES7 B;  4OM4 A;  3KFD E;  2CRS A;  1CB9 A;  3LAQ U;  1ERA A;  1PLO A;  1TXA A;  1BTE A;  1CRE A;  1JBD A;  3ERA A;  1KFH A;  2I9B E;  2J8B A;  1I02 A;  4OM5 A;  1CDS A;  3FEV A;  1KBA A;  1S4Y A;  2GOO C;  1MAH F;  5EBX A;  2H62 D;  1H0J A;  2X8B B;  4UY2 C;  1COD A;  1LX5 B;  1NTX A;  2ERA A;  1TGX A;  2N99 A;  2CCX A;  4P7U A;  4FAO E;  1NYU A;  5IMT D;  2MFA A;  3PLC A;  4ZQY A;  3NEQ A;  1FF4 A;  4BIK B;  1CRF A;  3KFD I;  1JGK A;  2MUO A;  1F8U B;  2OFS A;  2HLQ A;  2HLR A;  1KS6 A;  1ABT A;  2H62 C;  1KBT A;  1UG4 A;  3VTS A;  2LA1 A;  3EVS C;  1CTX A;  1NEA A;  3U74 U;  1CHV S;  1ZAD A;  1FAS A;  1KL8 A;  2H64 C;  1FRA A;  2H7Z B;  2MJ0 A;  3BT2 U;  1IDL A;  1KBS A;  1IDI A;  1CVO A;  1CDQ A;  2QJA C;  2H8U A;  3BT1 U;  2VLW A;  1IKC A;  3U73 U;  1LSI A;  1RGJ A;  2BTX A;  2H5F A;  2FD6 U;  3NH7 A;  2CDX A;  2L03 A;  2K3G A;  2CTX A;  2MJ4 A;  1REW C;  1HAA A;  4DO8 A;  1CCQ A;  2JVE A;  1HC9 B;  2GOO B;  1BXP A;  1QKE A;  2H64 B;  1ONJ A;  1F94 A;  1NYS A;  1V6P A;  2MHY A;  1QM7 A;  4HQP F;  1IJC A;  1B41 B;  1L4W A;  1IDH A;  3QB4 B;  5DU1 A;  1IQ9 A;  1FSS B;  1RL5 A;  2QJ9 C;  5DO6 A;  4RUD A;  1KXI A;  1LXG A;  1KTZ B;  1IK8 A;  1QKD A;  4LFT A;  1MR6 A;  1XT3 A;  2LCR A;  1ERG A;  2PJY C;  2H7Z A;  4IYE A; 
#chains in the Genus database with same CATH homology
 5DZ5 A;  1FFJ A;  4EY8 B;  2JQP A;  4QTI U;  2QC1 A;  1CDR A;  1KC4 A;  4FAO C;  1G6M A;  2UX2 A;  1CXN A;  1NOR A;  3NDS A;  1VB0 A;  2BHI A;  1NTN A;  5IMY C;  2CRT A;  4BDT B;  1FSC A;  1COE A;  1LXH A;  3HH7 A;  1DRS A;  1M9Z A;  3EBX A;  1CXO A;  1HC9 A;  2UWR A;  2PJY B;  1CDT A;  2QJB C;  1HOY A;  4AEA A;  2NBT A;  1IDG A;  1TFS A;  4XJJ A;  1YWH A;  4KSN A;  1NXB A;  1LJZ A;  6EBX A;  1W6B A;  2ABX A;  2L5S A;  2MJY A;  2MUP A;  1TXB A;  1JE9 A;  1KU6 B;  1HAJ A;  1ES7 B;  4OM4 A;  3KFD E;  2CRS A;  1CB9 A;  3LAQ U;  1ERA A;  1PLO A;  1TXA A;  1BTE A;  1CRE A;  1JBD A;  3ERA A;  1KFH A;  2I9B E;  2J8B A;  1I02 A;  4OM5 A;  1CDS A;  3FEV A;  1KBA A;  1S4Y A;  2GOO C;  1MAH F;  5EBX A;  2H62 D;  1H0J A;  2X8B B;  4UY2 C;  1COD A;  1LX5 B;  1NTX A;  2ERA A;  1TGX A;  2N99 A;  2CCX A;  4P7U A;  4FAO E;  1NYU A;  5IMT D;  2MFA A;  3PLC A;  4ZQY A;  3NEQ A;  1FF4 A;  4BIK B;  1CRF A;  3KFD I;  1JGK A;  2MUO A;  1F8U B;  2OFS A;  2HLQ A;  2HLR A;  1KS6 A;  1ABT A;  2H62 C;  1KBT A;  1UG4 A;  3VTS A;  2LA1 A;  3EVS C;  1CTX A;  1NEA A;  3U74 U;  1CHV S;  1ZAD A;  1FAS A;  1KL8 A;  2H64 C;  1FRA A;  2H7Z B;  2MJ0 A;  3BT2 U;  1IDL A;  1KBS A;  1IDI A;  1CVO A;  1CDQ A;  2QJA C;  2H8U A;  3BT1 U;  2VLW A;  1IKC A;  3U73 U;  1LSI A;  1RGJ A;  2BTX A;  2H5F A;  2FD6 U;  3NH7 A;  2CDX A;  2L03 A;  2K3G A;  2CTX A;  2MJ4 A;  1REW C;  1HAA A;  4DO8 A;  1CCQ A;  2JVE A;  1HC9 B;  2GOO B;  1BXP A;  1QKE A;  2H64 B;  1ONJ A;  1F94 A;  1NYS A;  1V6P A;  2MHY A;  1QM7 A;  4HQP F;  1IJC A;  1B41 B;  1L4W A;  1IDH A;  3QB4 B;  5DU1 A;  1IQ9 A;  1FSS B;  1RL5 A;  2QJ9 C;  5DO6 A;  4RUD A;  1KXI A;  1LXG A;  1KTZ B;  1IK8 A;  1QKD A;  4LFT A;  1MR6 A;  1XT3 A;  2LCR A;  1ERG A;  2PJY C;  2H7Z A;  4IYE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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